CN106540084A - A kind of blood-supplementing preparation, its preparation method and application - Google Patents
A kind of blood-supplementing preparation, its preparation method and application Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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Abstract
The invention discloses blood-supplementing preparation, which includes the raw material of following weight percent concentration：Rhizoma Polygonati 10～40%, Caulis Spatholobi 10～40%, Fructus Ligustri Lucidi 5～30%, Fructus Mori 5～30%, Fructus Lycii 5～30% and Fructus Jujubae 3～20%.The invention also discloses the preparation method of blood-supplementing preparation.By Rhizoma Polygonati, Caulis Spatholobi, Fructus Ligustri Lucidi, Fructus Mori, Fructus Lycii, Fructus Jujubae reasonable disposition together, the mutual compatibility of above-mentioned several raw medicinal materials is common to produce collaboration, potentiation, makes the blood-supplementing preparation of the present invention have significant nourishing blood function for the iron-supplementing preparation of the present invention.
Description
Technical field
The invention belongs to medicines and health protection field, more particularly to a kind of blood-supplementing preparation, its preparation method and application.
Background technology
Anemia has polytype, and iron deficiency anemia (IDA) is modal type in anemia, account for patients with various kinds of anemia 50%-
80%, belong to Deficiency disease.Malnutrition primary factor is iron deficiency.Iron deficiency anemia sickness rate accounts for 10% in world population-
20%.The sickness rate of developing country is higher than developed country, and women is higher than male, with baby, child, anemia of pregnant woman and the women of child-bearing age
Sickness rate is highest.
Although iron deficiency anemia morbidity it is not low, especially women due to physiological reason for example menorrhagia, gestation, suckling with
And other are such as bleeding hemorrhoidss, gastroenteropathy, parasite etc..But ferrous sulfate, this medicine pair are most commonly that in treatment
Gastric mucosa has stimulation, easily causes nausea and vomiting, draws melena, patient is produced panic and is difficult to receive.The serious patient of anemia is then
Blood transfusion is needed, need hospitalization.Give patient manpower, material resources, pressure economically.
The content of the invention
On the one hand, it is an object of the invention to overcome the weak point of prior art presence and provide one kind system of enriching blood
Agent, the blood-supplementing preparation of the present invention extract ferrum element from natural plants to improve Patients with iron deficiency anemia symptom, so that patient
Rehabilitate.
The technical solution used in the present invention is：A kind of blood-supplementing preparation, including the raw material of following weight percent concentration：
Used as the further improvement to above-mentioned technical proposal, described blood-supplementing preparation includes following weight percent concentration
Raw material：
Used as the further improvement to above-mentioned technical proposal, described blood-supplementing preparation includes following weight percent concentration
Raw material：
Used as the further improvement to above-mentioned technical proposal, the blood-supplementing preparation contains the ferrum element of 40～50 μ g/g.It is excellent
Selection of land, the blood-supplementing preparation contain the ferrum element of 40～50 μ g/g.
Used as the further improvement to above-mentioned technical proposal, the blood-supplementing preparation contains the calcium constituent of 180～190 μ g/g.
Preferably, the blood-supplementing preparation contains the calcium constituent of 180～190 μ g/g.
The blood-supplementing preparation can make oral liquid, tablet, granule, electuary, effervescent tablet, chewable tablet, buccal tablet, for oral administration
Piece or capsule, one of the present invention preferred embodiment in, the blood-supplementing preparation is blood-enriching oral liquid, described to enrich blood oral
Liquid also includes pharmaceutically acceptable adjuvant.
Used as the further improvement to above-mentioned technical proposal, the relative density 1.020～1.040 of the blood-supplementing preparation can
Dissolubility solid content is 6.0～10.0g/100mL.Wherein, relative density (proportion) is the relative density proportion at 25 DEG C.
On the other hand, present invention also offers the preparation method of described blood-supplementing preparation, comprises the following steps：1) will be described
Raw material is soaked 30～60 minutes, is heated to boiling, is simmered in water 1～2 hour, is collected extracting solution, is obtained the first extracting solution；
2) by Jing step 1) extract after raw material continue to add water and boil 0.8～1.5 hour, remove slag, obtain the second extracting solution；
3) merge first extracting solution and the second extracting solution, be concentrated into setting concentration, precipitate, obtain final product the system of enriching blood
Agent.
Another aspect, present invention also offers above-described blood-supplementing preparation improves nutritional anemia health food in preparation
In application.
Relative to prior art, beneficial effects of the present invention are：
The iron-supplementing preparation of the present invention is by Rhizoma Polygonati, Caulis Spatholobi, Fructus Ligustri Lucidi, Fructus Mori, Fructus Lycii, Fructus Jujubae reasonable disposition one
Rise, with excellent nourishing blood function.Wherein, Rhizoma Polygonati has functions that nourishing kidney lung moistening, spleen invigorating, supplementing QI and nourishing YIN, can play prevention
Cardiovascular disease mitigates arteriosclerosis, strengthens immunologic function, the effect of defying age；Caulis Spatholobi has a blood circulation promoting and enriching, menstruction regulating and pain relieving,
The effects such as relaxing muscles and tendons and activating QI and blood in the collateral；Fructus Ligustri Lucidi has functions that nourishing the liver and kidney, and pharmacology confirms that Fructus Ligustri Lucidi has two-ways regulation immunization,
There is rising effect and anti-senescence function to the leukopenia that radiotherapy causes；Fructus Mori have enrich blood YIN nourishing, fluid dryness it
Function, meanwhile, strengthen digestive function, strengthen intestinal fluid secretion and promote enterokinesia with gastric juice is supplemented, and immunologic function can be increased
Promote hemopoietic function；Fructus Lycii has a nourishing the liver and kidney, effect of replenishing vital essence to improve eyesight, and for insufficiency of the spleen labor asthenia of essence and blood, the deficiency of YIN is quenched one's thirst, together
When, with the function of improving immunity and slow down aging；Fructus Jujubae has mends stomach function regulating spleen invigorating, effect of supplementing QI for promoting the production of body fluid, for insufficiency of the spleen blood
Thanks to, the effects such as disharmony of nutrient QI with defensive QI.The mutual compatibility of above-mentioned several raw medicinal materials, it is common to produce collaboration, potentiation, make the benefit of the present invention
Blood preparation has significant nourishing blood function.
The iron-supplementing preparation of the present invention is docile health-oriented products, and safety coefficient is big, has no toxic side effect, it is adaptable to slight and strong
Body tonification person uses.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
There is no the title of anemia, but the syndrome presented from patient, such as pale complexion, the tired powerless, heart of body in Chinese medicine
Throb with fear, shortness of breath, dizziness, lassitude, thready pulse etc., then similar in appearance to " blood deficiency ", " deficiency of YIN " all diseases.Motherland's medical science thinks:Primary disease send out
It is raw in close relations with kidney with the heart, liver,spleen,kidney, especially spleen.The kidney being the origin of congenital constitution, and main bone gives birth to marrow, medullization blood.As kidney deficiency can
Make the heart, liver, three dirty function of spleen all empty, and then have impact on hemopoietic function；The spleen and stomach provide the material basis of the acquired, the source of blood biochemical, if taste
Damage, transporting is lost and is good for, and biochemical QI and blood hypofunction can then cause insufficiency of vital energy and blood.Therefore, in kidney not store essential substances, essence does not change blood, and liver is not
In the case of store blood, failure of the spleen to keep the blood flowing within the vessels, the not main blood of the heart, then lean blood disorder marquis is may occur in which.In treatment to blood deficiency person must QI invigorating because, "
The operation of blood depends on gas, therefore has " teacher of the gas for blood, gas row then blood, blood being the material foundation of QI, blood to gas also to " theory.So
The method for the treatment of both the principal and secondary aspects of a disease is only frequently with " qi and blood tonifying method ".The blood-enriching oral liquid of the present invention adopts medicine-food two-purpose medical material for raw material,
With QI invigorating, enrich blood with based on.
A kind of blood-supplementing preparation is embodiments provided, wherein, the blood-supplementing preparation includes that following percentage by weight is dense
The raw material of degree：
Wherein, the pharmacological property of above-mentioned raw materials medical material is as follows：
Dry rhizome of the Rhizoma Polygonati for liliaceous plant P. kingianum Polygonatum kingianum Coll.et Hemsl..
Rhizoma Polygonati has functions that nourishing kidney lung moistening, spleen invigorating, supplementing QI and nourishing YIN, for weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, asthenia of essence and blood
Card.Modern medical experiment is proved：There is Rhizoma Polygonati prevention of cardiovascular disease to mitigate arteriosclerosis, strengthen immunologic function, defying age
The effect of.Caulis Spatholobi is dried rattan for leguminous plant spatholobus suberectuss Spatholobus Suberectus Dunn's, mends with promoting blood circulation
The effects such as blood, menstruction regulating and pain relieving, relaxing muscles and tendons and activating QI and blood in the collateral.Drying of the Fructus Ligustri Lucidi for Oleaceae plants Fructus Ligustri Lucidi Ligustrum Iucidum Ait.
Mature fruit, has functions that nourishing the liver and kidney, and pharmacology confirms with two-ways regulation immunization, causes leukocyte to subtract radiotherapy
Rare rising effect and anti-senescence function.Fructus Mori is dried fruit ear plant for moraceae plants mulberry Morus alba L.'s.The Qing Dynasty eats
Treat doctor's Wang Shixiong to exist《Diet spectrum is occupied with breath》In point out, " Fructus Mori liver nourishing kidney, congested liquid, wind-damp dispelling are carried out in vigorous strides, cease asthenic fire, clearly
Asthenic fire ".Fructus Mori has the function of enrich blood YIN nourishing, fluid dryness, meanwhile, do not strengthen digestive function, strengthen with gastric juice is supplemented
Intestinal fluid secretion and promotion enterokinesia, and immunologic function promotion hemopoietic function can be increased.Fructus Lycii is matrimony vine of solanaceae plant Lyciun
The dry mature fruit of barbarum L., with nourishing the liver and kidney, effect of replenishing vital essence to improve eyesight, for insufficiency of the spleen labor asthenia of essence and blood, the deficiency of YIN
Quench one's thirst, meanwhile, with the function of improving immunity and slow down aging.Fructus Jujubae is Rhamnaceae plant Fructus Jujubae Ziziphus jujuba
Mill. mature fruit, with benefit stomach function regulating spleen invigorating, effect of supplementing QI for promoting the production of body fluid, for insufficiency of the spleen anemia, disharmony of nutrient QI with defensive QI etc..
The blood-supplementing preparation of the present invention is by Rhizoma Polygonati, Caulis Spatholobi, Fructus Ligustri Lucidi, Fructus Mori, Fructus Lycii, Fructus Jujubae reasonable disposition one
Rise, the mutual compatibility of each raw medicinal material is common to produce collaboration, potentiation, makes the nourishing blood function of blood-supplementing preparation of the present invention more
Substantially.
Preferably, above-mentioned blood-supplementing preparation includes the raw material of following weight percent concentration：
The iron supplement of the blood-supplementing preparation being made up of the raw material in above-mentioned amount ranges is better.
It is highly preferred that described blood-supplementing preparation includes the raw material of following weight percent concentration：
The iron supplement best results of the blood-supplementing preparation being made up of the raw material of above-mentioned consumption.
Blood-supplementing preparation provided by the present invention, can be obtained by various methods：Raw material Rhizoma Polygonati, Caulis Spatholobi, Fructus Ligustri Lucidi, Mulberry
Mulberry, Fructus Lycii, Fructus Jujubae are taken with medical material original powder form according to special ratios；Or by Rhizoma Polygonati, Caulis Spatholobi, Fructus Ligustri Lucidi, Fructus Mori,
Fructus Lycii, Fructus Jujubae press specific prescription proportioning, are extracted using conventional Traditional Chinese medicine extraction method；Or take accordingly according to prescription ratio
Raw medicinal material extract respectively after mixed extract.
In order to improve the effectiveness of blood-supplementing preparation of the present invention, in a kind of typical embodiment of the present invention, there is provided
A kind of preparation method of above-mentioned blood-supplementing preparation, comprises the following steps：1) raw material is soaked 30～60 minutes, is heated to
Boiling, simmers in water 1～2 hour, collects extracting solution, obtains the first extracting solution；2) by Jing step 1) extract after raw material continue to add water
Boil 0.8～1.5 hour, remove slag, obtain the second extracting solution；3) merge first extracting solution and the second extracting solution, be concentrated into setting
Concentration, precipitation, obtains final product the blood-supplementing preparation.
Relative density (25 DEG C) proportion of the blood-supplementing preparation is 1.015～1.040 (using densimeter [MC] 02810182
Number measure, Yuyao City Fang Qiao experiments instrucment and meter plant of Zhejiang Province produces)；Soluble solid therein (is adopted for 6.0～9.0g/100ml
Measured with Abbe refractometer), pH value is 4.0～5.5.
In actual applications, can add in above-mentioned blood-supplementing preparation one or more solid or liquid pharmaceutical excipients and/
Or adjuvant is combined, making can be as people with appropriate administration form or dosage form.
In a kind of typical embodiment of the present invention, blood-supplementing preparation is made into a kind of blood-enriching oral liquid, the clothes of enriching blood
Liquid also contains pharmaceutically acceptable adjuvant.
Above-mentioned blood-supplementing preparation can be used for preparation and improve nutritional anemia health food.
Effect of blood-supplementing preparation of the present invention is further illustrated below with reference to specific embodiment.
Embodiment 1
A kind of blood-supplementing preparation, wherein, the blood-supplementing preparation includes the raw material of following weight：
The blood-supplementing preparation of the present embodiment is blood-enriching oral liquid, and its preparation method comprises the following steps：Raw material (is processed into little
Section) soak 40 minutes, boiling is heated to, is simmered in water 1.5 hours, receipts extracting solution adds water 4 times and boils 1 hour, removes slag, and merges two
Liquid, is concentrated into setting concentration, precipitation, packs (standby).
Embodiment 2
A kind of blood-supplementing preparation, wherein, the blood-supplementing preparation includes the raw material of following weight：
The blood-supplementing preparation of the present embodiment is blood-enriching oral liquid, and its preparation method comprises the following steps：Raw material (is processed into little
Section) soak 30 minutes, boiling is heated to, is simmered in water 1.5 hours, receipts extracting solution adds water 4 times and boils 1 hour, removes slag, and merges two
Liquid, is concentrated into setting concentration, precipitation, packs (standby).
Embodiment 3
A kind of blood-supplementing preparation, wherein, the blood-supplementing preparation includes the raw material of following weight：
The blood-supplementing preparation of the present embodiment is blood-enriching oral liquid, and its preparation method comprises the following steps：Raw material (is processed into little
Section) soak 60 minutes, boiling is heated to, is simmered in water 1.5 hours, receipts extracting solution adds water 4 times and boils 1 hour, removes slag, and merges two
Liquid, is concentrated into setting concentration, precipitation, packs (standby).
Embodiment 4
A kind of blood-supplementing preparation, wherein, the blood-supplementing preparation includes the raw material of following weight：
The blood-supplementing preparation of the present embodiment is blood-enriching oral liquid, and its preparation method comprises the following steps：Raw material (is processed into little
Section) soak 60 minutes, boiling is heated to, is simmered in water 1.5 hours, receipts extracting solution adds water 4 times and boils 1 hour, removes slag, and merges two
Liquid, is concentrated into setting concentration, precipitation, packs (standby).
Embodiment 5
A kind of blood-supplementing preparation, wherein, the blood-supplementing preparation includes the raw material of following weight：
The blood-supplementing preparation of the present embodiment is blood-enriching oral liquid, and its preparation method comprises the following steps：Raw material (is processed into little
Section) soak 50 minutes, boiling is heated to, is simmered in water 1.5 hours, receipts extracting solution adds water 4 times and boils 1 hour, removes slag, and merges two
Liquid, is concentrated into setting concentration, precipitation, packs (standby).
Embodiment 6
A kind of blood-supplementing preparation, wherein, the blood-supplementing preparation includes the raw material of following weight：
The blood-supplementing preparation of the present embodiment is blood-enriching oral liquid, and its preparation method comprises the following steps：Raw material (is processed into little
Section) soak 60 minutes, boiling is heated to, is simmered in water 1.5 hours, receipts extracting solution adds water 4 times and boils 1 hour, removes slag, and merges two
Liquid, is concentrated into setting concentration, precipitation, packs (standby).
Embodiment 7
A kind of blood-supplementing preparation, wherein, the blood-supplementing preparation includes the raw material of following weight：
The blood-supplementing preparation of the present embodiment is blood-enriching oral liquid, and its preparation method comprises the following steps：Raw material (is processed into little
Section) soak 30 minutes, boiling is heated to, is simmered in water 1.5 hours, receipts extracting solution adds water 4 times and boils 1 hour, removes slag, and merges two
Liquid, is concentrated into setting concentration, precipitation, packs (standby).
Embodiment 8
Think according to WHO:Iron deficiency and iron deficiency anemia are global problems.In Asia iron deficiency anemia sickness rate, grow up
Male is 10%, and, more than 20%, child is more than 50% for women.China's sickness rate surpasses the world average level.Especially women with
The quickening of modern life rhythm, and is periodically lost blood on female pathology etc. and to be caused the loss of ferrum so that iron deficiency anemia is sent out
Sick rate constantly rises.The blood-supplementing preparation of the present invention uses medicine-food two-purpose medical material as raw material, through meticulous, rational formula, makes
Improve the health food of iron deficiency anemia.It is verified by experiments：After taking this product, serum levels of iron, hemoglobin, reticulocyte counts can
Increase significantly, therefore this product has preferable nourishing blood function.The effect of the present invention is proved below by way of pharmacodynamics test.Test
Used in blood-supplementing preparation be blood-enriching oral liquid, the relative density of the blood-supplementing preparation is 1.020～1.040, solubility solid
Thing is 6.0～10.0g/100mL.
1st, experiment material and method
The SD male rats 100 that laboratory animal is provided by No.1 Military Medical Univ.'s Experimental Animal Center, body weight 50-70 gram
(quality certification number:The dynamic inspection space in Guangdong:2001A034).Animal model is fed using low iron base feed formula, and this formula Jing is former
It is 8.5PPM that sub- absorptiometry determines iron-holder.Laboratory sample is by No.1 Military Medical Univ.'s natural plants applied research center
There is provided.Experiment point 2 stages are carried out, and the first stage uses 100 healthy SD rats, wherein 10 feeding chow diets, 90 hello
Eat low iron base feedstuff 3 weeks, then heart extracting blood determines each item data, to obtain the animal model of iron deficiency anemia.Second-order
Anemia in Rats is divided at random by Duan Ze by Hemoglobin Value and body weight：Normal raising group, model group, in pre- ferrum group, experiment (it is high, in,
It is low) dosage group.Wherein, normal raising group feeding chow diet, the low iron base feedstuff of model group feeding, in it is pre- in pre- ferrum group feeding
Ferrum, tests the blood-supplementing preparation of the equal feeding present invention of (high, medium and low) dosage group, wherein, the dosage for testing high dose group is 10ml/
Kg, the dosage for testing middle dose group are 5ml/kg, and the dosage for testing low dose group is 2.5ml/kg.Each group animal uses rustless steel
Mouse cage single cage is raised, and is drunk deionized water etc., is strictly prevented the pollution and cross-contamination to each other of external ferrum.
2nd, experimental result
2.1Resistance to iron deficiency anemia effect is determined
Suffer from iron deficiency anemia person it is common the reason for be physiological need increase as it is pregnant shake, suckling, chronic hemorrhage such as disease of bursting, hemorrhoid go out
Caused by blood, ferrum suction deficiency etc..This experiment replicates anemia in rats model using low ferrum forage feed, treats through blood-enriching oral liquid
After three weeks, some leading indicators such as serum levels of iron, hemoglobin, reticulocyte are significantly changed, as a result such as 1～table of table, 3 institute
Show.
1 blood-supplementing preparation of the present invention of table is to improving the experimental result of iron deficiency anemia serum levels of iron
Explanation：Compare with normal group, * * P<0.01；Compare with model group, ▲ ▲ P<0.01；
Compare with before treatment, #P<0.05, ##P<0.01.
Above it is demonstrated experimentally that the serum levels of iron value of each dosage group of experimental group is than being significantly increased before experiment, and it is in dose-effect relationship.
2 blood-supplementing preparation of the present invention of table is to improving the result of hemoglobin
Explanation：Compare with normal group, * * P<0.01；
Compare with before treatment, #P<0.05, ##P<0.01.
The blood red white value ratio of each dosage group of Jing blood-supplementing preparations is than being significantly increased before treatment as can be seen from Table 2, and is in
Dose-effect relationship.
3 blood-supplementing preparation of the present invention of table is to improving the result of reticulocyte
Explanation：Compare with before treatment, #P<0.05, ##P<0.01.
Jing after blood-supplementing preparation of the present invention treatment, the reticulocyte counts of each experimental group are significantly increased as can be seen from Table 3, and
In dose-effect relationship.
Summary result:The serum levels of iron of each group animal, hemoglobin, reticulocyte after oral blood-supplementing preparation of the present invention
Be significantly increased, therefore, the present invention blood-supplementing preparation with to improving iron deficiency anemia the effect of.
2.2Nutrient is determined
Trace elements iron, calcium catalyst：
Ferrum content in vivo has very big difference with age, sex, nutrition and health status.Ferrum presses its function in vivo
Feature ferrum and storage ferrum can be divided into.Feature ferrum accounts for 70%, is distributed in hemoglobin mostly.Remaining storage ferrum is accounted for
30%.Human body iron deficiency is a progressive process, and from the incomplete absorption of ferrum, numerous storage in vivo is consumed, and engender form it is scarce
Ferrum anemia.Therefore, the measure of ferrum contributes to the situation for judging iron content.In body in the presence of calcium, ferrum absorption of disinthibiting can be removed
Phosphate radical, oxalate and phytic acid root.Contribute to the absorption of ferrum.Blood-supplementing preparation 40～50 μ g/g containing ferrum element of the present invention, calcium unit
180～190 μ g/g of element；In the embodiment above, blood-supplementing preparation 45.8 μ g/g containing ferrum element, 184 μ g/g of calcium constituent of the invention.
2.3Determination of acute toxicity
Fed 7 days with blood-enriching oral liquid, each group mouse diet, activity are normal, hair color gloss, none is dead.Mouse stomach
Maximum tolerated dose (MTD) is 2400ml/kg, then mice to the maximum tolerated dose multiple of people be (0.8ml × 3 × 2/20g)/
(50000g+30ml)=400 times.Show that people is fool proof with blood-enriching oral liquid
Last should be noted that above example is only to illustrate technical scheme rather than the present invention is protected
The restriction of shield scope, although being explained in detail to the present invention with reference to preferred embodiment, one of ordinary skill in the art should
Understand, technical scheme can be modified or equivalent, without deviating from the essence of technical solution of the present invention
And scope.
Claims (9)
1. a kind of blood-supplementing preparation, it is characterised in that：Including the raw material of following weight percent concentration：
2. blood-supplementing preparation according to claim 1, it is characterised in that：Including the raw material of following weight percent concentration：
3. blood-supplementing preparation according to claim 1, it is characterised in that：Including the raw material of following weight percent concentration：
4. blood-supplementing preparation according to claim 1, it is characterised in that：The blood-supplementing preparation contains the ferrum unit of 40～50 μ g/g
Element.
5. blood-supplementing preparation according to claim 1, it is characterised in that：The blood-supplementing preparation contains the calcium of 180～190 μ g/g
Element.
6. blood-supplementing preparation according to claim 1, it is characterised in that：The blood-supplementing preparation be blood-enriching oral liquid, the benefit
Blood oral liquor also includes pharmaceutically acceptable adjuvant.
7. blood-supplementing preparation according to claim 6, it is characterised in that：The relative density of the blood-supplementing preparation be 1.020～
1.040, soluble solid is 6.0～10.0g/100mL.
8. the preparation method of the blood-supplementing preparation according to any one of claim 1～7, it is characterised in that：Including following step
Suddenly：
1) raw material is soaked 30～60 minutes, is heated to boiling, simmers in water 1～2 hour, collect extracting solution, obtain the
One extracting solution；
2) by Jing step 1) extract after raw material continue to add water and boil 0.8～1.5 hour, remove slag, obtain the second extracting solution；
3) merge first extracting solution and the second extracting solution, be concentrated into setting concentration, precipitate, obtain final product the blood-supplementing preparation.
9. the blood-supplementing preparation according to any one of claim 1～7 improves in nutritional anemia health food in preparation
Using.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108721498A (en) * | 2017-04-21 | 2018-11-02 | 霍叶兰 | A kind of profound female's fair complexion cream Ci |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112832A (en) * | 1993-12-03 | 1995-12-06 | 李应昆 | Qi-blood nourishing oral liquid |
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2016
- 2016-12-12 CN CN201611139010.9A patent/CN106540084A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1112832A (en) * | 1993-12-03 | 1995-12-06 | 李应昆 | Qi-blood nourishing oral liquid |
Non-Patent Citations (1)
| Title |
|---|
| 张彩山: "《<本草纲目>中药养生速查全书》", 30 September 2013, 天津科学技术出版社 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108721498A (en) * | 2017-04-21 | 2018-11-02 | 霍叶兰 | A kind of profound female's fair complexion cream Ci |
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