CN106539946A - Easypro dormancy medicated pillow of a kind of macadimia nut Pericarpium Citri Reticulatae Viride and preparation method thereof - Google Patents

Easypro dormancy medicated pillow of a kind of macadimia nut Pericarpium Citri Reticulatae Viride and preparation method thereof Download PDF

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CN106539946A
CN106539946A CN201611139499.XA CN201611139499A CN106539946A CN 106539946 A CN106539946 A CN 106539946A CN 201611139499 A CN201611139499 A CN 201611139499A CN 106539946 A CN106539946 A CN 106539946A
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macadimia nut
parts
pericarpium citri
citri reticulatae
reticulatae viride
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徐斌
万举河
卢淼
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JIANGCHENG ZHONGAO AGRICULTURE TECHNOLOGY DEVELOPMENT Co Ltd
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JIANGCHENG ZHONGAO AGRICULTURE TECHNOLOGY DEVELOPMENT Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47GHOUSEHOLD OR TABLE EQUIPMENT
    • A47G9/00Bed-covers; Counterpanes; Travelling rugs; Sleeping rugs; Sleeping bags; Pillows
    • A47G9/007Bed-covers; Counterpanes; Travelling rugs; Sleeping rugs; Sleeping bags; Pillows comprising deodorising, fragrance releasing, therapeutic or disinfecting substances
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47GHOUSEHOLD OR TABLE EQUIPMENT
    • A47G9/00Bed-covers; Counterpanes; Travelling rugs; Sleeping rugs; Sleeping bags; Pillows
    • A47G9/10Pillows
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

A kind of easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride, is made up of the component of following mass ratio:40 60 parts of macadimia nut Pericarpium Citri Reticulatae Viride extract, 20 30 parts of pine needle powder, 20 30 parts of Herba Albiziae corium farinosum, 10 15 parts of Radix Polygalae powder, 0.1 1.0 parts of macadimia nut flower essential oil, 0.1 1.0 parts of Herba Lysimachiae foenum-graeci quintessence oil, 0.1 1.0 parts of Fructus Citri Limoniae quintessence oil, 0.1 1.0 parts of cypress quintessence oil, 0.1 1.0 parts of Bergamot.Macadimia nut Pericarpium Citri Reticulatae Viride relaxes the preparation method of dormancy medicated pillow:Macadimia nut Pericarpium Citri Reticulatae Viride extract, pine needle powder, Herba Albiziae corium farinosum, Radix Polygalae powder are mixed in a ratio, add the ethanol solution of quintessence oil sustained-release preparation, load after fully mixing in non-woven bag, the easypro dormancy medicated bag of macadimia nut Pericarpium Citri Reticulatae Viride of every part of 10g is obtained, medicated pillow in-core is put into, the easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride after suture, is prepared into.

Description

Easypro dormancy medicated pillow of a kind of macadimia nut Pericarpium Citri Reticulatae Viride and preparation method thereof
Technical field
The invention belongs to health care product scope, and in particular to a kind of easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride and its preparation side Method.
Background technology
Macadimia nut Macadamia ternifoliaF.Muell be Proteaceae (Proteaceae), macadimia nut category (Macadamia), belong to aiphyllium, dicotyledon originates in the subtropical zones rain of Queensland ,Australia and New South Wales Woods.Macadamia kernel has unique local flavor and abundant nutritional labeling, is one of world-renowned four big nuts, America and Europe is considered as one of nut on table best in the world, has " dry fruit queen " good reputation.
Start 60~seventies of 20th century of macadimia nut to introduce China.In recent years, Yunnan Province of China is saved and is greatly developed, tentatively Formation industry, especially after Dehong prefecture introducing and planting, implantation in large scale, and will progressively become Dehong prefecture Main Economic forest products Product.With the development of China's economic, growth in the living standard, macadimia nut are generally received as Semen Juglandiss, Semen Armeniacae Amarum, Fructus anacardii.
Macadimia nut has been cultivated in a large number in Yunnan Province suitable area, has achieved appreciable Jing since introduce a fine variety Yunnan Ji benefit.Macadimia nut has become one of Major agro-industries on ground such as Dehong prefecture.The main utilization portion of current macadimia nut It is kernel to divide, therefore, the basis and exploitation research to kernel achieves great successes, has defined industrialization.But It is to carry out rational full fruit to develop and comprehensively utilize to Yunnan nut, remains our province macadimia nut industry extension industry chain synthesis Using and improve the major issue that faces of macadimia nut added value.
The Pericarpium Citri Reticulatae Viride of macadimia nut is used as to make compost and feedstuff on a small quantity, and the overwhelming majority is not exploited, and big as garbage Amount is abandoned, and a large amount of active substances contained in Pericarpium Citri Reticulatae Viride are not reasonably developed substantially, and utilization ratio is extremely low.The present invention Early-stage Study and data show that the Pericarpium Citri Reticulatae Viride of macadimia nut, rich in medicine adornment active component such as vitamin, tannin, arbutin, is developed It is feasible to become the high product of added value.
The present invention carries out systematic quantification analysis to Pericarpium Citri Reticulatae Viride medicine adornment active component, and the exploitation for medicine adornment product is provided in theory Support;Effective extraction to Pericarpium Citri Reticulatae Viride medicine adornment active component, the exploitation for medicine adornment product provide technical guarantee;Finally develop Comfortable health-care medicated pillow with macadimia nut Pericarpium Citri Reticulatae Viride extract, macadimia nut flower essential oil as key component, is later stage Pericarpium Citri Reticulatae Viride comprehensive exploitation Using laying the first stone.
By literature survey, from equal Helicia plant Helicia nilagirica, former name Radix Raphani tree H.erraticaHook. Seed in isolate helicide (helicid) [5] and helicide II (helicid II), to methylol benzene-O- β-D- Ahs Lip river pyranoside);Helicide, helicide III (helicid III, PARA FORMALDEHYDE PRILLS(91,95) base are isolated from the fruit of mountain region mountain longan Benzene-O- β-D- glucopyranosides), nakedness nakedness chestnut glycosides (clivicolide, to group-4 ethyl formate benzene-O- β-D- glucopyanosyls Glycosides);Helicide, helicide III, nakedness nakedness chestnut glycosides, flame sequence glycosides are isolated from the fruit of flame sequence mountain longan (pyrrhobotryide, 2- carboxaldehyde radicals benzene-O- β-D- A Luo pyranoses (6 → 1)-O- β-D- A Luo pyranosides) and β-paddy steroid Alcohol.Isolate 5 kinds of methods of glycosides and cupreol so far from the platymiscium.And the chemical composition of macadimia nut Pericarpium Citri Reticulatae Viride Report is had no, early-stage Study shows, the chemistry that arbutin, tannic acid etc. can be used for medicine adornment product is contained in this kind of plant Pericarpium Citri Reticulatae Viride part Composition, therefore with very big potentiality to be exploited.
Macadimia nut Pericarpium Citri Reticulatae Viride mainly contains macadimia nut Pericarpium Citri Reticulatae Viride glue, phlegmatic temperament and polysaccharide etc., and " natural " is present tense for institute Pursue, natural health care product, with wide development space and application prospect.Macadimia nut Pericarpium Citri Reticulatae Viride extract is slow Decompression force, pressure of releiving, calm the nerves, sleeping etc. is all many-sided has good effect, therefore the health care containing macadimia nut Pericarpium Citri Reticulatae Viride The research of product is also into a kind of trend of macadimia nut Pericarpium Citri Reticulatae Viride economic worth research.At present, not yet have with Australia in prior art Nut Pericarpium Citri Reticulatae Viride extract, macadimia nut flower essential oil are the report of the comfortable health-care medicated pillow of key component and preparation method thereof.
The content of the invention
Present invention aims to the blank that prior art is present, there is provided it is a kind of with macadimia nut Pericarpium Citri Reticulatae Viride extract, Comfortable health-care medicated pillow of the macadimia nut flower essential oil for key component, and preparation method and application.
In order to realize the above-mentioned purpose of the present invention, the invention provides following technical scheme:
A kind of easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride, which is made up of the component of following mass ratio:Macadimia nut Pericarpium Citri Reticulatae Viride Extract 40-60 parts, pine needle powder 20-30 parts, Herba Albiziae corium farinosum 20-30 part, Radix Polygalae powder 10-15 parts, macadimia nut flower essential oil 0.1- 1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae quintessence oil 0.1-1.0 parts, cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1- 1.0 part.
According to a kind of easypro dormancy medicated pillow of described macadimia nut Pericarpium Citri Reticulatae Viride, described macadimia nut flower essential oil is to make according to the following steps Standby:By macadimia nut fresh inflorescence distilled water immersion 20-30min, distilled using vapor, distillation axe temperature is 90-110 DEG C, 4-6h is distilled, collect distillate and quintessence oil, be placed in 4-6 DEG C of refrigerator, separated out quintessence oil, obtain macadimia nut HUAJING Oil.
According to a kind of easypro dormancy medicated pillow of described macadimia nut Pericarpium Citri Reticulatae Viride, described macadimia nut Pericarpium Citri Reticulatae Viride extract is by following step Rapid preparation:Macadimia nut is dried Pericarpium Citri Reticulatae Viride to be crushed, is all sieved by 20 mesh medicines, add the alcohol reflux of 60-80% to carry Take 2-3 time, each 2-3h, filter, merging filtrate, concentrating under reduced pressure, 60-80 DEG C of thickening temperature, relative density is concentrated into for 0.9- 1.2mg/mL, obtains macadimia nut Pericarpium Citri Reticulatae Viride extract.
Relaxed dormancy medicated pillow according to a kind of described macadimia nut Pericarpium Citri Reticulatae Viride, described pine needle powder, Herba Albiziae corium farinosum and Radix Polygalae powder be by What following methods were prepared:Above-mentioned medical material is crushed to respectively and is all sieved by No. 9 medicines, respectively obtain Folium Pini powder, Herba Albiziae Corium farinosum end and Thinleaf Milkwort Root.
According to a kind of easypro dormancy medicated pillow of described macadimia nut Pericarpium Citri Reticulatae Viride, described quintessence oil makes sustained-release preparation, by such as lower section Method is prepared:By macadimia nut flower essential oil 0.1-1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae quintessence oil 0.1-1.0 parts, silk Cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1-1.0 parts are proportionally added into the ethanol of the 70-95% containing sustained-release preparation In solution, quintessence oil sustained-release preparation is obtained.
According to a kind of easypro dormancy medicated pillow of described macadimia nut Pericarpium Citri Reticulatae Viride, described quintessence oil is with vanillin, neck phthalic acid ethyl ester Or benzyl benzoate a kind or several constituted sustained-release preparations therein are substituted.
According to a kind of easypro dormancy medicated pillow of described macadimia nut Pericarpium Citri Reticulatae Viride, described quintessence oil sustained-release preparation is made into ethanol molten Liquid, is prepared by the following method:The sustained-release preparation is added into ethanol solution, concentration is prepared into for 1.0-2.0 μm of ol/mL Ethanol solution, obtain the ethanol solution of sustained-release preparation.
The preparation method of dormancy medicated pillow invention also provides a kind of macadimia nut Pericarpium Citri Reticulatae Viride relaxes, the method are blue or green by macadimia nut Peel extract, pine needle powder, Herba Albiziae corium farinosum, Radix Polygalae powder are mixed in a ratio, add the ethanol of quintessence oil sustained-release preparation Solution, loads the easypro dormancy medicated bag of macadimia nut Pericarpium Citri Reticulatae Viride that every part of 10g is obtained in non-woven bag, is put into medicated pillow in-core after fully mixing, The easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride is prepared into after suture.The described ethanol solution that sustained-release preparation is made containing quintessence oil, by as follows Method is prepared:By macadimia nut flower essential oil 0.1-1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae quintessence oil 0.1-1.0 parts, Cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1-1.0 parts are proportionally added into the second of the 70-95% containing sustained-release preparation In alcoholic solution, quintessence oil sustained-release preparation is obtained;Or described whole quintessence oils are with vanillin, neck phthalic acid ethyl ester or benzoic acid Benzyl ester a kind or several constituted sustained-release preparations therein are substituted;Then the sustained-release preparation is added into 70-95%'s Ethanol solution, is prepared into the ethanol solution that concentration is 1.0-2.0 μm of ol/mL, obtains the ethanol solution of sustained-release preparation.
Macadimia nut Macadamia ternifoliaF.Muell be Proteaceae (Proteaceae), macadimia nut category (Macadamia) plant.Macadimia nut Pericarpium Citri Reticulatae Viride mainly contains macadimia nut Pericarpium Citri Reticulatae Viride polyphenol, natural arbutin and polysaccharide etc., this Bright employing phytochemistry separation means extract macadimia nut Pericarpium Citri Reticulatae Viride polysaccharide, macadimia nut Pericarpium Citri Reticulatae Viride water from macadimia nut Pericarpium Citri Reticulatae Viride medical material The difference extract such as extract, macadimia nut Pericarpium Citri Reticulatae Viride polyphenol, determines the antioxidation and cheese ammonia of different macadimia nut Pericarpium Citri Reticulatae Viride extract Sour enzyme inhibition activity, by determining macadimia nut Pericarpium Citri Reticulatae Viride water extract antityrosinase activity highest, its concentration presses down for 60mg/ml Rate processed is 68.5%, and macadimia nut Pericarpium Citri Reticulatae Viride water extract antioxidant activity is also highest, and its concentration is 40mg/ml antioxidant activity For 95.1%, therefore, macadimia nut Pericarpium Citri Reticulatae Viride water extract is prepared into macadimia nut Pericarpium Citri Reticulatae Viride moisturizing by 60mg/ml of concentration by the present invention Aquation adornment breast, is that the exploitation of macadimia nut Pericarpium Citri Reticulatae Viride extract lay the foundation.
Specific embodiment:
Below with embodiments of the invention further illustrating the essentiality content of the present invention, but not with this limiting this Invention.
Embodiment 1:
A kind of easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride, is made up of the component of following mass ratio:Macadimia nut Pericarpium Citri Reticulatae Viride extract 40-60 parts, pine needle powder 20-30 parts, Herba Albiziae corium farinosum 20-30 part, Radix Polygalae powder 10-15 parts, macadimia nut flower essential oil 0.1-1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae quintessence oil 0.1-1.0 parts, cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1-1.0 parts.
Described macadimia nut flower essential oil is prepared according to the following steps:By macadimia nut fresh inflorescence distilled water immersion 20-30min, is distilled using vapor, and distillation axe temperature is 90-110 DEG C, distills 4-6h, collects distillate and quintessence oil, puts Put in 4-6 DEG C of refrigerator, separate out quintessence oil, obtain macadimia nut flower essential oil.
Described macadimia nut Pericarpium Citri Reticulatae Viride extract is prepared by the following step:Macadimia nut is dried Pericarpium Citri Reticulatae Viride carries out powder It is broken, all sieved by 20 mesh medicines, the alcohol reflux of addition 60-80% 2-3 time, each 2-3h are filtered, and merging filtrate subtracts Pressure concentration, 60-80 DEG C of thickening temperature, it is 0.9-1.2mg/mL to be concentrated into relative density, obtains macadimia nut Pericarpium Citri Reticulatae Viride extract.
Described pine needle powder, Herba Albiziae corium farinosum and Radix Polygalae powder are prepared by following methods:Above-mentioned medical material is pressed respectively Weighed according to the above-mentioned part by weight of medicated pillow, be crushed to and all sieved by No. 9 medicines, respectively obtain Folium Pini powder, Herba Albiziae corium farinosum End and Thinleaf Milkwort Root.
Described quintessence oil makes sustained-release preparation, is prepared by the following method:By macadimia nut flower essential oil 0.1-1.0 Part, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae quintessence oil 0.1-1.0 parts, cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1-1.0 Part is proportionally added in the ethanol solution of the 70-95% containing sustained-release preparation, obtains quintessence oil sustained-release preparation.
Described quintessence oil a kind or several is constituted so that vanillin, neck phthalic acid ethyl ester or benzyl benzoate are therein Sustained-release preparation substituted.
Then described quintessence oil sustained-release preparation is made into ethanol solution, is prepared by the following method:By the slow control Release formulation adds ethanol solution, is prepared into the ethanol solution that concentration is 1.0-2.0 μm of ol/mL, and the ethanol for obtaining sustained-release preparation is molten Liquid.
The preparation method of dormancy medicated pillow invention also provides a kind of macadimia nut Pericarpium Citri Reticulatae Viride relaxes, the method are blue or green by macadimia nut The mass ratio of peel extract, pine needle powder, Herba Albiziae corium farinosum, Radix Polygalae powder as described in above-mentioned formula is mixed, and adds quintessence oil to delay The ethanol solution of controlled release preparation, loads the easypro dormancy medicine of macadimia nut Pericarpium Citri Reticulatae Viride that every part of 10g is obtained in non-woven bag after fully mixing Bag, is put into medicated pillow in-core, and the easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride is prepared into after suture.Described makes sustained-release preparation containing quintessence oil Ethanol solution, is prepared by the following method:By macadimia nut flower essential oil 0.1-1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, lemon Lemon quintessence oil 0.1-1.0 parts, cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1-1.0 parts are proportionally added into containing sustained-release preparation 70-95% ethanol solution in, obtain quintessence oil sustained-release preparation;Or described whole quintessence oils are with vanillin, neck benzene diformazan Acetoacetic ester or benzyl benzoate a kind or several constituted sustained-release preparations therein are substituted;Then by the slow controlled release Preparation adds the ethanol solution of 70-95%, is prepared into the ethanol solution that concentration is 1.0-2.0 μm of ol/mL, obtains sustained-release preparation Ethanol solution.
It is an advantage of the current invention that prepare tranquilizing by nourishing the heart medicated pillow using herbal raw material, without chemistry addition, without it is poisonous into Point, pure Chinese medicine compatibility, along with sustained-release preparation is prepared into using medicament novel technique, is conducive to medicine slowly to discharge, and increases The effectiveness and long-term effectiveness of dosing pillow, simultaneously, mind tranquilizing and the heart calming can treat many social mentalities disease at present to hypnotic, Such as climacteric syndrome, depression, neurasthenia etc..A kind of in July, 2016 invention disclosed patent application " Radix Rhodiolae synthesis Using make sedative health-care pillow method " Radix Rhodiolae is extracted only with common Chinese medicine pretreatment technology after medicinal residues sterilization after Load medicated pillow and prepare medicated pillow, single medicinal material effect is not complete, and medicinal residues cannot also play curative effect, and traditional Chinese medicine medical pillow plays the master of effect Mode is wanted to be absorption of human body during volatile small molecule is slept by diffusion and play the effect calmed the nerves, with the present invention Compare, will original based on the functional component bean curd glycoside of the sedative action is rich in using macadimia nut Pericarpium Citri Reticulatae Viride itself by the present invention Material, compatibility other Traditional Chinese medicine for tranquilization, along with the compound action of volatile oil, can be calmed the nerves composition by sleep absorption small molecule, directly Effect is picked up, the medicated pillow instant effect has no toxic side effect, in conjunction with slow controlled-release technology by the efficacy exertion of medicated pillow to maximum, can be effective Hypnotic, tranquilizing by nourishing the heart, are a kind of effective health-care medicine pillows of natural environmental-protective.

Claims (8)

1. a kind of macadimia nut Pericarpium Citri Reticulatae Viride relaxes dormancy medicated pillow, it is characterised in which is made up of the component of following mass ratio:Australia Nut Pericarpium Citri Reticulatae Viride extract 40-60 parts, pine needle powder 20-30 parts, Herba Albiziae corium farinosum 20-30 part, Radix Polygalae powder 10-15 parts, macadimia nut flower Quintessence oil 0.1-1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae quintessence oil 0.1-1.0 parts, cypress quintessence oil 0.1-1.0 parts, Fructus Citri Sarcodactyliss Quintessence oil 0.1-1.0 parts.
2. a kind of easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride according to claims 1, it is characterised in that described macadimia nut Flower essential oil is prepared according to the following steps:By macadimia nut fresh inflorescence distilled water immersion 20-30min, entered using vapor Row distillation, distillation axe temperature are 90-110 DEG C, distill 4-6h, collect distillate and quintessence oil, are placed in 4-6 DEG C of refrigerator, are separated out Quintessence oil, obtains macadimia nut flower essential oil.
3. a kind of easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride according to claims 1, it is characterised in that described macadimia nut Pericarpium Citri Reticulatae Viride extract is prepared by the following step:Macadimia nut is dried Pericarpium Citri Reticulatae Viride to be crushed, is all sieved by 20 mesh medicines, added The alcohol reflux of 60-80% 2-3 time, each 2-3h are filtered, and merging filtrate, concentrating under reduced pressure, 60-80 DEG C of thickening temperature are dense It is 0.9-1.2mg/mL to be reduced to relative density, obtains macadimia nut Pericarpium Citri Reticulatae Viride extract.
4. a kind of macadimia nut Pericarpium Citri Reticulatae Viride according to claims 1 relaxes dormancy medicated pillow, it is characterised in that described pine needle powder, close Joyous corium farinosum and Radix Polygalae powder are prepared by following methods:Above-mentioned medical material is crushed to respectively and is all sieved by No. 9 medicines, respectively Obtain Folium Pini powder, Silktree Albizia Bark and Thinleaf Milkwort Root.
5. the easypro dormancy medicated pillow of a kind of macadimia nut Pericarpium Citri Reticulatae Viride according to claims 1, it is characterised in that described quintessence oil is made Sustained-release preparation, is prepared by the following method:By macadimia nut flower essential oil 0.1-1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae quintessence oil 0.1-1.0 parts, cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1-1.0 parts are proportionally added into containing slow controlled release system In the ethanol solution of the 70-95% of agent, quintessence oil sustained-release preparation is obtained.
6. the easypro dormancy medicated pillow of a kind of macadimia nut Pericarpium Citri Reticulatae Viride according to claims 5, it is characterised in that described quintessence oil is with perfume (or spice) Lan Su, neck phthalic acid ethyl ester or benzyl benzoate a kind or several constituted sustained-release preparations therein are substituted.
7. the easypro dormancy medicated pillow of a kind of macadimia nut Pericarpium Citri Reticulatae Viride according to claims 5 or 6, it is characterised in that by described quintessence oil Sustained-release preparation makes ethanol solution, is prepared by the following method:Will be the ethanol of sustained-release preparation addition 70-95% molten Liquid, is prepared into the ethanol solution that concentration is 1.0-2.0 μm of ol/mL, obtains the ethanol solution of sustained-release preparation.
8. a kind of macadimia nut Pericarpium Citri Reticulatae Viride described in claims 1 relaxes the preparation method of dormancy medicated pillow, it is characterised in that the method will Macadimia nut Pericarpium Citri Reticulatae Viride extract, pine needle powder, Herba Albiziae corium farinosum, Radix Polygalae powder are mixed in a ratio, are added containing the slow control of quintessence oil The ethanol solution of release formulation, loads the easypro dormancy medicated bag of macadimia nut Pericarpium Citri Reticulatae Viride that every part of 10g is obtained in non-woven bag after fully mixing, Medicated pillow in-core is put into, the easypro dormancy medicated pillow of macadimia nut Pericarpium Citri Reticulatae Viride, the described second that sustained-release preparation is made containing quintessence oil after suture, is prepared into Alcoholic solution, is prepared by the following method:By macadimia nut flower essential oil 0.1-1.0 parts, Herba Lysimachiae foenum-graeci quintessence oil 0.1-1.0 parts, Fructus Citri Limoniae Quintessence oil 0.1-1.0 parts, cypress quintessence oil 0.1-1.0 parts, Bergamot 0.1-1.0 parts are proportionally added into containing sustained-release preparation In the ethanol solution of 70-95%, quintessence oil sustained-release preparation is obtained;Or described whole quintessence oils are with vanillin, neck phthalic acid Ethyl ester or benzyl benzoate a kind or several constituted sustained-release preparations therein are substituted;Then by the slow controlled release system Agent adds the ethanol solution of 70-95%, is prepared into the ethanol solution that concentration is 1.0-2.0 μm of ol/mL, obtains the second of sustained-release preparation Alcoholic solution.
CN201611139499.XA 2016-12-12 2016-12-12 Easypro dormancy medicated pillow of a kind of macadimia nut Pericarpium Citri Reticulatae Viride and preparation method thereof Pending CN106539946A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101438658A (en) * 2008-12-24 2009-05-27 吴江市农业生态科技有限公司 Fragrance-smelling section for improving sleep
CN102319305A (en) * 2011-08-08 2012-01-18 蔡欣 Dormitive incense
CN104855434A (en) * 2015-04-28 2015-08-26 何睿杰 Mosquito-repellent incense
CN105219554A (en) * 2015-10-14 2016-01-06 周庆莉 A kind of hair washing of mind-tranquilizing brain-strengthening is taken a shower and is mixed soap
CN105695270A (en) * 2016-04-06 2016-06-22 暨南大学 Macadamia nut wine with sleep improvement function and production method thereof
CN105713725A (en) * 2016-03-17 2016-06-29 南京大塘金药用与芳香植物研究所 Space capsule and plant compound essential oil for lowering blood pressure and application method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101438658A (en) * 2008-12-24 2009-05-27 吴江市农业生态科技有限公司 Fragrance-smelling section for improving sleep
CN102319305A (en) * 2011-08-08 2012-01-18 蔡欣 Dormitive incense
CN104855434A (en) * 2015-04-28 2015-08-26 何睿杰 Mosquito-repellent incense
CN105219554A (en) * 2015-10-14 2016-01-06 周庆莉 A kind of hair washing of mind-tranquilizing brain-strengthening is taken a shower and is mixed soap
CN105713725A (en) * 2016-03-17 2016-06-29 南京大塘金药用与芳香植物研究所 Space capsule and plant compound essential oil for lowering blood pressure and application method thereof
CN105695270A (en) * 2016-04-06 2016-06-22 暨南大学 Macadamia nut wine with sleep improvement function and production method thereof

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Application publication date: 20170329