CN106539730A - A kind of conditioning of the anti-acne containing basil oil essence and preparation method thereof - Google Patents
A kind of conditioning of the anti-acne containing basil oil essence and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of conditioning of the anti-acne containing basil oil essence and preparation method thereof, it includes following raw material：A phase raw materials：Trehalose, 1,3 Propylene Glycol, hyaluronate sodium, hydrolysis Scleroglucan, glycerol, deionized water；B phase raw materials：Semen Coicis extract, glycyrrhizic acid dipotassium；C phase raw materials：Polysorbate20,1,2 pentanediols, glycerol caprylate, basil oil.The present invention passes through many experiments preferred feedstock, prepare skin is nursed one's health with good deep layer, toxin expelling sterilizes, anti-acne, speckle dispelling, crease-resistant, whitening, the anti-acne conditioning essence for moistening moisturizing, promoting blood circulation to remove blood stasis and toxin expelling granulation promoting effect, constitutive material of the present invention are gentle, have no toxic side effect, safety is good, especially has good prevention effect to dermatosis such as acnes, has wide range of applications.
Description
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of conditioning essence of the anti-acne containing basil oil and its preparation
Method.
Technical background
Comedo, acne, skin sore are medically referred to as acne, are a kind of common sebaceous gland chronic diseases, and its origin cause of formation is
During adolescence, internal hormone can stimulate hair growth, and smegma is vigorous, cause clogging of pores to form an acne
Core --- micropowder is pierced.Micropowder thorn is invisible, and micropowder thorn grows skin surface needs 6 to 9 months from being formed to
Trophophase.Micropowder thorn blocking pore induction inflammation, is that pimple, pustule, tuberosity and cyst originate root.Basic reason is interior point
Imbalance is secreted, androgen secretion is vigorous to be caused.The cause of disease of acne is also relevant with some pathogenic bacterial infections, it has already been proven that acne send out
Life is relevant with propanoic acid corynebacterium acneses infection.This corynebacterium acneses are parasitized in hebetic pilosebaceous unit, are passed through
The effect of lipase, hydrolyzable triglyceride produce more free fatty, and these free fatties can make hair follicle and hair follicle week
Generation nonspecific inflammation reaction is enclosed, when inflammation is heavier, pustule, cyst is may occur in which.It is more for the medicine of acne at present, but
Curative effect is undesirable, and there is certain side effect.
Modern study shows：Basil oil main component is ocimene, α-trip's alkene, 1,8- cineoles, linalool, ridge cattle
Alcohol, limonene, Cao's alkene one 3, estragole, eugenol, methyleugenol, mattress perfume ether, cinnamic acid first are cruel, hexene -8-
Alcohol -1, octanone -3 and furfural etc., eliminate scabies, blood circulation promoting, aging resistance, treatment powder with spasmolytic, sterilization, except hiding from
Thorn, Rosemary Extract etc. are acted on；In addition with the effect such as functional disorder, stabilizing the emotions, anti-depression of refreshing oneself, improve.Basil oil is very
It is fresh and sweet, the fragrant and sweet abnormal smells from the patient with grass.
Semen Coiciss are rich in multivitamin, oils and fatss, saccharide and mineral, and energy Glycerin makes skin smooth, reduces wrinkle
Stricture of vagina, eliminates pigment spot, also has absorbability to ultraviolet.Wet effect, energy are mended in the moist skin whitening that Semen Coiciss have
The function of skin metabolism and moisturizing is improved, scaly dry skin can be effectively prevented.
To sum up, act on using the extremely strong Transdermal absorption of Basil Essential, sterilization and except elimination scabies is hidden from so as to which skin is had
Very well the tool such as anti-acne, the effect for the treatment of acne, then some Semen Coicis extracts of compatibility and glycyrrhizic acid dipotassium nourish, moisture-keeping function
Composition, has functions that to prevent and treat acne well.
The content of the invention
Goal of the invention：Present invention aim to address the deficiencies in the prior art, there is provided one kind independently can directly penetrate into skin
Skin skin corium, it is easy to be absorbed by the skin, can solve the problem that because clogging of pores cause scytitiss, the problems such as the colour of skin is obscure,
There is the conditioning essence of the anti-acne containing basil oil of preferable moisturizing anti-acne effect.Another object of the present invention is to provide containing basil oil
Anti-acne nurse one's health essence preparation method.
Technical scheme：In order to realize object above, the technical scheme that the present invention takes is：
A kind of conditioning of the anti-acne containing basil oil essence, it is made up of the raw material of following percentage by weight:
A phase raw materials：Trehalose 1～3%, 1,3- Propylene Glycol 1～5%, hyaluronate sodium 0.07～0.13%, hydrolysis Scleroglucan
0.15～0.23%, glycerol 2～6%, deionized water 75～85%；
B phase raw materials：Semen Coicis extract 2～7%, glycyrrhizic acid dipotassium 0.15～0.65%；
C phase raw materials：Polysorbate -20 0.07～0.14%, 1,2- pentanediols 3～8%, glycerol caprylate 0.06～0.15%,
Basil oil 0.01～0.05%.
Preferably, the above-described conditioning of the anti-acne containing basil oil essence, it is by following percentage by weight
Raw material is made:
A phase raw materials：Trehalose 2%, 1,3- Propylene Glycol 3%, hyaluronate sodium 0.1%；Hydrolysis Scleroglucan 0.2%, glycerol 4%, go from
Sub- water 81.08%；
B phase raw materials：Semen Coicis extract 4%, glycyrrhizic acid dipotassium 0.4%；
C phase raw materials：Polysorbate -20 0.1%, 1,2- pentanediols 5%, glycerol caprylate 0.1%, basil oil 0.02%.
Semen Coiciss, plus the deionized water of 5～15 times of volumes of Semen Coiciss weight are weighed, after being heated to boiling, is started every half an hour
Agitator once, maintain fluidized state 1～4 hour, obtain Semen Coiciss aqueous extract, cross 100～400 mesh filter clothes, medicinal residues add 4 again
The water of～12 times of amounts, agitating heating maintain fluidized state 1～3 hour, obtain Semen Coiciss aqueous extract, cross 100～400 mesh filter clothes,
Slag of getting it filled adds 4～12 times of water measured again, and agitating heating maintains fluidized state 1～3 hour, merges 3 times and extracts the filtrate for obtaining,
20 DEG C of relative densities about 1. 0～1. 03 are concentrated into, appropriate beta-schardinger dextrin-or/and Fructus Hordei Germinatus in Semen Coiciss concentrated solution, are added
Dextrin, after stirring, is spray-dried（110 DEG C～200 DEG C of inlet temperature, 50 DEG C～90 DEG C of leaving air temp, flow are
150mL/h～1000mL/h）, obtain Semen Coicis extract；
Described basil oil preparation method is：Herba Ocimi (Herba Ocimi Pilosi) herb is taken, the water of dosing material 6 ~ 15 times of volumes of weight is steamed using vapor
Evaporate method and extract prepared.
The function of above-mentioned each component is as follows：
The basil oil has spasmolytic, sterilization, blood circulation promoting, aging resistance, treats the effect such as acne, Rosemary Extract；And
And have and refresh oneself, the effects such as improve functional disorder, stabilizing the emotions, anti-depression.
The Semen Coicis extract can make skin delicate fine and smooth, eliminate mottle, so as to improve skin texture, color and luster and bright
Degree.
The glycyrrhizic acid dipotassium is used as anti-freckle agent, anti-allergic agent.
The trehalose can cell surface layer formed one layer of special protecting film, can not only keep the original nutrition of skin and
Moisture, moreover it is possible to nourishes rough skin cell.Skin sunburn can be avoided simultaneously, reduce melanin deposition, effective defying age.
Moisture is stayed in horny layer as aqueouss wetting agent by the 1,3-PD, while the vicidity of glycerol can be reduced,
Again because add glycerol it is therefore, the consumption of 1,3-PD, attenuating zest can be reduced.
The hyaluronate sodium can form thin film in skin surface, make skin produce good smooth feeling and moistening
Sense；With scavenging activated oxygen, can promote the regeneration of injury skin, supply and the waste of skin-nourishing can be promoted
Excretion, so as to prevent skin aging, plays face-nursing function；Hygroscopic capacity highest under low relative humidity (33%), and high relative
Hygroscopic capacity under humidity (75%) is minimum, adapts to skin and preferable moisturizing work is respectively provided with Various Seasonal, varying environment humidity
With；Thickening and Stabilization can also be played.
It is described hydrolysis Scleroglucan can help emulsion-stabilizing and control viscosity, improve stability, and also can in case
Only pigment separated；The ratio of oil in formula can be also reduced, with the innate efficacy releived with glabrous skin.
Moisture in the absorbable air of the glycerol, makes skin keep moistening, and moisture-keeping function is strong.
The polysorbate -20 belongs to oil-in-water emulsifiers, used as solubilizing agent.
1, the 2- pentanediols also have functions that antibacterial, solubilising as wetting agent.
The glycerol caprylate is Multifunctional protective humectant, fatting agent, and short close ester carbochain penetrates into and adsorb in human skin
Lipid part, therefore its hydrophilic group can in the more preferable moisturizing of horny layer, while have potent antibacterial activity, show
The activity of good anti-gram- bacteria.
After the multiple active component of the above and base starting material scientific compatibility, stable performance, and independently directly can penetrate to the skin
Skin corium, it is easy to be absorbed by the skin, can solve the problem that because clogging of pores cause scytitiss, the problems such as the colour of skin is obscure, it is right
Prevent and treat the dermatosis such as acne and there is good effect.It is when during prescription screening, of the invention according to effect to be reached,
Selected various safely and effectively compositions, and on the basis of each component recommends consumption, screened by many experiments, carry out repeatedly
Test, the final prescription and preparation technology for determining the invention described above essence.
Anti-acne containing basil oil of the present invention nurses one's health the preparation method of essence, comprises the following steps：
（1）Agitated kettle deionized water is cleaned, high-temperature steam sterilization is used;
（2）Deionized water in A phase raw materials is added in agitated kettle, then by the hydrolysis Scleroglucan in A phase raw materials, hyalomitome
After sour sodium is uniformly dispersed with appropriate 1,3-PD respectively, add together with the 1,3-PD of glycerol, trehalose and surpluses
To in agitated kettle, 75～85 DEG C are stirred and are warming up to, material body is uniformly incubated 15～30 minutes afterwards；
（3）Stirring is cooled to 38～50 DEG C, is incubated, and then stirs lower addition B phase raw materials, mix homogeneously；
（4）After C phase raw materials are pre-mixed uniformly, step is added（3）In agitated kettle, stir；Continue stirring and be cooled to 35
～45 DEG C, filtering and discharging, obtains anti-acne conditioning essence after the assay was approved.
Preferably, the above-described anti-acne containing basil oil nurses one's health the preparation method of essence, including following step
Suddenly：
（1）Agitated kettle deionized water is cleaned, high-temperature steam sterilization is used;
（2）Deionized water in A phase raw materials is added in agitated kettle, then by the hydrolysis Scleroglucan in A phase raw materials, hyalomitome
After sour sodium is uniformly dispersed with appropriate 1,3-PD respectively, add together with the 1,3-PD of glycerol, trehalose and surpluses
To in agitated kettle, 80 DEG C are stirred and are warming up to, material body is uniformly incubated 20 minutes afterwards；
（3）Stirring is cooled to 45 DEG C, is incubated, and then adds B phase raw materials, mix homogeneously under 35 revs/min of stirrings；
（4）After C phase raw materials are pre-mixed uniformly, step is added（3）Agitated kettle in, 35 revs/min stir；Continue stirring
40 DEG C are cooled to, after the assay was approved filtering and discharging, obtain anti-acne conditioning essence.
Beneficial effect：Compared to the prior art the conditioning of the anti-acne containing the basil oil essence that the present invention is provided has following excellent
Point：
The present invention is prepared and nurses one's health skin with good deep layer by many experiments preferred feedstock, and toxin expelling sterilizes, anti-acne,
Speckle dispelling, crease-resistant, whitening, the anti-acne conditioning essence for moistening moisturizing, promoting blood circulation to remove blood stasis and toxin expelling granulation promoting effect, constitutive material of the present invention
Gently, have no toxic side effect, nonirritant, safety is good, especially has good prevention effect to dermatosis such as acnes.
Specific embodiment
The present invention is further elucidated with reference to specific embodiment, it should be understood that these embodiments be merely to illustrate the present invention and
Restriction the scope of the present invention is not used in, after the present invention has been read, various of equal value shape of the those skilled in the art to the present invention
The modification of formula falls within the application claims limited range.
Embodiment 1
1st, a kind of conditioning of the anti-acne containing basil oil essence, it is made up of the raw material of following percentage by weight:
A phase raw materials：Trehalose 2kg, 1,3- Propylene Glycol 3kg, hyaluronate sodium 0.1kg；Hydrolysis Scleroglucan 0.2kg, glycerol
4kg, deionized water 81.08kg；
B phase raw materials：Semen Coicis extract 4kg, glycyrrhizic acid dipotassium 0.4kg；
C phase raw materials：- 20 0.1kg, 1,2- pentanediol 5kg of polysorbate, glycerol caprylate 0.1kg, basil oil 0.02kg.
The above-described anti-acne containing basil oil nurses one's health essence, and the preparation method of described Semen Coicis extract is：Weigh the heart of a lotus seed
Semen Coicis, in input extractor, plus the deionized water of 12 times of amounts, after being heated to boiling, agitator is started once every half an hour, so that
Extract complete.Maintain fluidized state 4 hours, Semen Coiciss aqueous extract crosses 300 mesh filter clothes, then plus 10 times of amounts water, agitating heating,
Maintain fluidized state 3 hours, Semen Coiciss aqueous extract crosses 300 mesh filter clothes, then extracts third time, and filtrate merges, and is concentrated into phase
1.04 are about to density, its solid content is determined.Appropriate beta-schardinger dextrin-or/and maltodextrin etc. are added in Semen Coiciss concentrated solution,
After stirring, it is spray-dried under conditions of being 750m1/h in 170 DEG C of inlet temperature, 70 DEG C of leaving air temp, flow, obtains the heart of a lotus seed
Semen Coicis extract.
Described basil oil preparation method is：Take Herba Ocimi (Herba Ocimi Pilosi) herb, the water of dosing material 12 times of volumes of weight, using vapor
The way of distillation is extracted 2 hours and is obtained.
2nd, the anti-acne containing basil oil nurses one's health the preparation method of essence, comprises the following steps：
（1）Agitated kettle deionized water is cleaned, high-temperature steam sterilization is used;
（2）81.08kg deionized waters are added in agitated kettle, 0.2kg is hydrolyzed into Scleroglucan and 0.1kg hyaluronate sodiums then
After being uniformly dispersed with 0.5kg 1,3-PDs respectively, with 4kg glycerol, 2kg trehaloses and 2kg 1,3-PDs again together with plus
Enter in agitated kettle, stir and be warming up to 80 DEG C, material body is uniformly incubated 20 minutes afterwards.
（3）Stirring is cooled to 45 DEG C, is incubated, then stirs（35 revs/min）In the case of sequentially add 0.4kg glycyrrhizic acids two
Potassium, 4kg Semen Coicis extracts, mix homogeneously.
（4）By 0.1kg polysorbate -20,5 kg 1, after 2- pentanediols, 0.1kg glycerol caprylate mix homogeneously, plus
Enter agitated kettle stirring（35 revs/min）Uniformly；Continue stirring and be cooled to 40 DEG C, after the assay was approved filtering and discharging.
Embodiment 2
1st, a kind of conditioning of the anti-acne containing basil oil essence, it is made up of the raw material of following percentage by weight:
A phase raw materials：Trehalose 3kg, 1,3- Propylene Glycol 5kg, hyaluronate sodium 0.13kg, hydrolysis Scleroglucan 0.23kg, glycerol
6kg, deionized water 85kg；
B phase raw materials：Semen Coicis extract 7kg, glycyrrhizic acid dipotassium 0.65kg；
C phase raw materials：- 20 0.14kg, 1,2- pentanediol 8kg of polysorbate, glycerol caprylate 0.15kg, basil oil 0.05kg.
The above-described anti-acne containing basil oil nurses one's health essence, and the preparation method of described Semen Coicis extract is：Claim
Semen Coiciss are taken, in input extractor, plus the deionized water of 10 times of amounts, after being heated to boiling, agitator is started once every half an hour,
So as to extract complete.Maintain fluidized state 3 hours, Semen Coiciss aqueous extract crosses 300 mesh filter clothes, then plus 8 times of amounts water, stirring plus
Heat, maintains fluidized state 2 hours, and Semen Coiciss aqueous extract crosses 300 mesh filter clothes, then extracts third time, and filtrate merges, and is concentrated into
Relative density is about 1.02, determines its solid content.Appropriate beta-schardinger dextrin-or/and maltodextrin are added in Semen Coiciss concentrated solution
Deng, after stirring, in 160 DEG C of inlet temperature, 75 DEG C of leaving air temp, flow be 550m1/h under conditions of be spray-dried, obtain
Semen Coicis extract.
Described basil oil preparation method is：Take Herba Ocimi (Herba Ocimi Pilosi) herb, the water of dosing material 10 times of volumes of weight, using vapor
The way of distillation is extracted 1.5 hours and is obtained.
2nd, the anti-acne containing basil oil nurses one's health the preparation method of essence, comprises the following steps：
（1）Agitated kettle deionized water is cleaned, high-temperature steam sterilization is used;
（2）85kg deionized waters are added in agitated kettle, 0.23kg is hydrolyzed into Scleroglucan and 0.13kg hyaluronate sodiums then
After being uniformly dispersed with 0.5kg 1,3-PDs respectively, with 6kg glycerol, 3kg trehaloses and 4kg 1,3-PDs again together with plus
Enter in agitated kettle, stir and be warming up to 80 DEG C, material body is uniformly incubated 20 minutes afterwards.
（3）Stirring is cooled to 45 DEG C, is incubated, then stirs（35 revs/min）In the case of sequentially add 0.65kg glycyrrhizic acids two
Potassium, 7kg Semen Coicis extracts, mix homogeneously.
（4）By 0.14kg polysorbate -20,8 kg 1, after 2- pentanediols, 0.15kg glycerol caprylate mix homogeneously,
Add agitated kettle stirring（35 revs/min）Uniformly；Continue stirring and be cooled to 40 DEG C, after the assay was approved filtering and discharging.
The conditioning essence actual efficacy of the anti-acne containing basil oil of embodiment 3：
1. Miss Mao, 19 years old, using front, forehead and the long pox of cheek were more than 1 year；Elite is nursed one's health using 1 anti-acne of the embodiment of the present invention
Liquid, using once, after one month, pox disappears, and without pockmark, face is pale, glossy, the toxic and side effects such as non-stimulated, follow-up 3 within 1 day
Individual month, not long pox again.
2. Miss Xu, 24 years old, using front, the multiple place length of face had acne, and there is half a year the time, and has skin dark stain；Using this
1 anti-acne of bright embodiment nurses one's health essence, and after one month, medicine for treating comedo skin dark stain of becoming estranged substantially weakens using once within 1 day, without pockmark,
Skin smooth, Shui Run, white touched with red, the toxic and side effects such as non-stimulated, follow-up 3 months do not recur again.
3. Mr. Ding, 26 years old, using front, skin pore was thick, and the colour of skin is black, around lip and forehead length has comedo；Make
Essence is nursed one's health with 2 anti-acne of the embodiment of the present invention, after one month, pox disappears using once within 1 day, and without pockmark, skin is white, stingless
The toxic and side effects such as sharp property, follow-up 3 months, long pox again, not very satisfied to this product.
4 activity experiment of embodiment
Jing antioxidation and anti-pigmentation test result indicate that, the anti-acne containing basil oil that the embodiment of the present invention 1 and 2 is prepared
Conditioning essence has functions that good antioxidation and anti-pigmentation.
Embodiment 5
30 sensitive skin persons, experimental result table are applied to using the conditioning essence of the anti-acne containing basil oil that the present invention is provided
Bright, continuous all using 2 to 4, only 2 there is slight stimulation allergy, show without obvious irritation, can receive.
The above is only the preferred embodiment of the present invention, it is noted that for those skilled in the art come
Say, under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be regarded as
Protection scope of the present invention.
Claims (5)
1. a kind of anti-acne containing basil oil nurses one's health essence, it is characterised in that it is made up of the raw material of following percentage by weight:
A phase raw materials：Trehalose 1～3%, 1,3- Propylene Glycol 1～5%, hyaluronate sodium 0.07～0.13%, hydrolysis Scleroglucan
0.15～0.23%, glycerol 2～6%, deionized water 75～85%；
B phase raw materials：Semen Coicis extract 2～7%, glycyrrhizic acid dipotassium 0.15～0.65%；
C phase raw materials：Basil oil 0.01～0.05%, polysorbate -20 0.07～0.14%, 1,2- pentanediols 3～8%, glycerol
Caprylate 0.06～0.15%.
2. the anti-acne containing basil oil according to claim 1 nurses one's health essence, it is characterised in that it is by following weight percent
The raw material of ratio is made:
A phase raw materials：Trehalose 2%, 1,3- Propylene Glycol 3%, hyaluronate sodium 0.1%；Hydrolysis Scleroglucan 0.2%, glycerol 4%, go from
Sub- water 81.08%；
B phase raw materials：Semen Coicis extract 4%, glycyrrhizic acid dipotassium 0.4%；
C phase raw materials：Basil oil 0.02%, polysorbate -20 0.1%, 1,2- pentanediols 5%, glycerol caprylate 0.1%.
3. the anti-acne containing basil oil according to claim 1 and 2 nurses one's health essence, it is characterised in that described Semen Coiciss
The preparation method of extract is：Semen Coiciss, plus the deionized water of 5～15 times of volumes of Semen Coiciss weight are weighed, after being heated to boiling,
Agitator is started once every half an hour, maintain fluidized state 1～4 hour, obtain Semen Coiciss aqueous extract, cross 100～400 mesh
Filter cloth, medicinal residues add 4～12 times of water measured again, and agitating heating maintains fluidized state 1～3 hour, obtains Semen Coiciss aqueous extract, mistake
100～400 mesh filter clothes, slag of getting it filled add 4～12 times of water measured again, and agitating heating maintains fluidized state 1～3 hour, merges 3 times
The filtrate that obtains of extraction, is concentrated into 20 DEG C of relative densities about 1. 0～1. 03, add in Semen Coiciss concentrated solution appropriate β-
Cyclodextrin or/and maltodextrin, after stirring, are spray-dried, obtain Semen Coicis extract；
Described basil oil preparation method is：Herba Ocimi (Herba Ocimi Pilosi) herb is taken, the water of dosing material 6 ~ 15 times of volumes of weight is steamed using vapor
Evaporate method and extract prepared.
4. the anti-acne containing basil oil described in claim 1 or 2 nurses one's health the preparation method of essence, it is characterised in that include with
Lower step：
（1）Agitated kettle deionized water is cleaned, high-temperature steam sterilization is used;
（2）Deionized water in A phase raw materials described in claim 1 or 2 is added in agitated kettle, then by A phase raw materials
After hydrolysis Scleroglucan, hyaluronate sodium are uniformly dispersed with appropriate 1,3-PD respectively, with glycerol, trehalose and surpluses
1,3-PD is added in agitated kettle together, stirs and be warming up to 75～85 DEG C, and material body is uniformly incubated 15～30 minutes afterwards；
（3）Stirring is cooled to 38～50 DEG C, is incubated, and then stirs the lower B phase raw materials added described in claim 1 or 2, and mixing is equal
It is even；
（4）After C phase raw materials described in claim 1 or 2 are pre-mixed uniformly, step is added（3）In agitated kettle, stirring is equal
It is even；Continue stirring and be cooled to 35～45 DEG C, after the assay was approved filtering and discharging, obtain anti-acne conditioning essence.
5. anti-acne containing basil oil according to claim 4 nurses one's health the preparation method of essence, it is characterised in that include with
Lower step：
（1）Agitated kettle deionized water is cleaned, high-temperature steam sterilization is used;
（2）Deionized water in A phase raw materials described in claim 1 or 2 is added in agitated kettle, then by A phase raw materials
After hydrolysis Scleroglucan, hyaluronate sodium are uniformly dispersed with appropriate 1,3-PD respectively, with glycerol, trehalose and surpluses
1,3-PD is added in agitated kettle together, stirs and be warming up to 80 DEG C, and material body is uniformly incubated 20 minutes afterwards；
（3）Stirring is cooled to 45 DEG C, is incubated, and the B phase raw materials described in claim 1 or 2 is then added under 35 revs/min of stirrings, is mixed
Close uniform；
（4）After C phase raw materials described in claim 1 or 2 are pre-mixed uniformly, step is added（3）In agitated kettle, 35 revs/min
Stir；Continue stirring and be cooled to 40 DEG C, after the assay was approved filtering and discharging, obtain anti-acne conditioning essence.
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Cited By (1)
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