CN106420526A - Basil oil acne-removing regulating cream and preparation method thereof - Google Patents

Basil oil acne-removing regulating cream and preparation method thereof Download PDF

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Publication number
CN106420526A
CN106420526A CN201610960622.8A CN201610960622A CN106420526A CN 106420526 A CN106420526 A CN 106420526A CN 201610960622 A CN201610960622 A CN 201610960622A CN 106420526 A CN106420526 A CN 106420526A
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raw material
extract
phase
basil oil
pot
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张俊清
秦贞苗
李海龙
赖伟勇
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Hainan Medical College
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Hainan Medical College
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Abstract

The invention discloses basil oil acne-removing regulating cream and a preparation method thereof. The cream is prepared from phase A raw materials including squalene, methl glucse sesquistearate, cetostearyl alcohol, PEG-20 methl glucse sesquistearate, PEG-100 stearate, polydimethylsiloxane, aloe extract and avena sativa kernel oil, phase B raw materials including 1,3-propanediol, glycerinum, hydrolyzed sclerotium gum, sodium hyaluronate, sodium polyacrylate and deionized water, a phase C raw material including coix seed extract, tremella fuciformis extract and dipotassium glycyrrhizinate, and a phase D raw material including glycerol caprylate, basil oil and 1,2-pentanediol. Raw materials are selected through a great number of experiments, and the prepared basil oil acne-removing regulating cream has the effects of deeply regulating skin, removing toxicity, sterilizing skin, removing acnes and freckles, relieving wrinkles, whitening skin, moistening skin, promoting blood circulation to remove stasis and promoting granulation, and has the advantages of mild raw materials, no toxic or side effect and good safety.

Description

A kind of basil oil anti-acne conditioning frost and preparation method thereof
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of basil oil anti-acne conditioning frost and preparation method thereof.
Technical background
Comedo, acne, skin sore are medically referred to as acne, are a kind of common sebaceous gland chronic diseases, and its origin cause of formation is During adolescence, internal hormone can stimulate hair growth, and smegma is vigorous, cause clogging of pores to form acne Core micropowder is pierced.Micropowder thorn is invisible, and micropowder thorn grows skin surface needs 6 to 9 months from being formed to Trophophase.Micropowder thorn blocking pore induction inflammation, be pimple, pustule, tuberosity and cyst originate root.Basic reason is interior point Imbalance is secreted, androgen secretion is vigorous to be caused.The cause of disease of acne is also relevant with some pathogenic bacterial infections, it has already been proven that acne send out Life is relevant with propanoic acid corynebacterium acneses infection.This corynebacterium acneses are parasitized in hebetic pilosebaceous unit, are passed through The effect of lipase, hydrolyzable triglyceride, more free fatty is produced, these free fatties can make hair follicle and hair follicle week Generation nonspecific inflammation reaction is enclosed, when inflammation is heavier, may occur in which pustule.More for the medicine of acne at present, but curative effect Undesirable, and there is certain side effect.
Modern study shows:Oleum Ocimi Gratissimi main component is ocimene, α-trip's alkene, 1,8- cineole, linalool, ridge Geraniol, limonene, Cao's alkene one 3, estragole, eugenol, methyleugenol, mattress perfume ether, cinnamic acid first are cruel, oneself Alkene -8- alcohol -1, octanone -3 and furfural etc., with spasmolytic, sterilization, eliminate scabies, blood circulation promoting, aging resistance, control except hiding from Treat the effect such as acne, Rosemary Extract;In addition with the effect such as functional disorder, stabilizing the emotions, anti-depression of refreshing oneself, improve.Basil oil Very fresh and sweet, with grass fragrant and sweet abnormal smells from the patient.
Semen Coiciss are made skin smooth, reduce wrinkle rich in multivitamin, oils and fatss, saccharide and mineral, energy Glycerin Stricture of vagina, eliminates pigment spot, also has absorbability to ultraviolet.Wet effect, energy are mended in the moist skin whitening that Semen Coiciss have Skin metabolism and the function of moisturizing is improved, can effectively prevent scaly dry skin.
Tremella is mild-natured nontoxic, and rich in 17 kinds of aminoacid and vegetalitas colloid, it is needed by human wherein to have ten several aminoacid Aminoacid, also contain several mineral materials, such as phosphorus, ferrum, calcium, potassium, magnesium, sodium, sulfur etc., containing pentosan, mannitol, Sargassum Sugar etc., nutritive value is very high.
To sum up, act on using the extremely strong Transdermal absorption of Ocimum Basilicum quintessence oil, sterilization and except elimination scabies is hidden from so as to skin Effect with fine anti-acne, treatment acne, then scientific compatibility Aloe extract, oat kernel oil, Tremella extract, Semen Coiciss carry The composition of the effects such as the tool nourishing such as thing and glycyrrhizic acid dipotassium, moisturizing, whitening, sun-proof, anti-inflammation is taken, with preventing and treating Cuo well Effect of skin ulcer.
Content of the invention
Goal of the invention:Present invention aim to address the deficiencies in the prior art, provide one kind and independently can directly penetrate into skin Skin skin corium, it is easy to be absorbed by the skin, can solve the problem that because the problems such as scytitiss that cause of clogging of pores, the colour of skin are obscure, There is the basil oil anti-acne conditioning frost of good moisturizing, anti-acne, beauty, speckle dispelling, antiinflammatory and other effects.Another object of the present invention is to carry Preparation method for the basil oil anti-acne conditioning frost.
Technical scheme:In order to realize object above, the technical scheme that the present invention takes is:
A kind of basil oil anti-acne conditioning frost, it is made up of the raw material of following percentage by weight:
A phase raw material:Angle Trionyx sinensis Wiegmann alkane 2-7%, methyl sesquistearate 1.2-1.8%, cetearyl alcohol 1.3-1.7%, PEG-20 Methyl sesquistearate 1-4%, PEG-100 stearate 0.5-1.5%, polydimethylsiloxane 1-3%, Aloe are extracted Thing 1-5%, oat kernel oil 0.5-1.5%;
B phase raw material:1,3- Propylene Glycol 3-8%, glycerol 3-7%, hydrolysis Scleroglucan 0.08-0.14%, hyaluronate sodium 0.08- 0.13%th, sodium polyacrylate 0.2-0.8%, deionized water 62-68%;
C phase raw material:Semen Coicis extract 2-6%, Tremella extract 0.3-0.7%, glycyrrhizic acid dipotassium 0.2-0.6%;
D phase raw material:Glycerol caprylate 0.08-0.14%, basil oil 0.03-0.08%, 1,2- pentanediol 3-8%.
Preferably, above-described basil oil anti-acne conditioning frost, it is made up of the raw material of following percentage by weight:
A phase raw material:Angle Trionyx sinensis Wiegmann alkane 4%, methyl sesquistearate 1.5%, cetearyl alcohol 1.5%, PEG-20 methyl Sesquistearate 2%, PEG-100 stearate 1%, polydimethylsiloxane 1.5%, 3 % of Aloe extract, oat kernel oil 1%;
B phase raw material:1,3- Propylene Glycol 4%, glycerol 5%, hydrolysis Scleroglucan 0.1%, hyaluronate sodium 0.1%, sodium polyacrylate 0.5%th, deionized water 64.75%;
C phase raw material:Semen Coicis extract 4%, Tremella extract 0.5%, glycyrrhizic acid dipotassium 0.4%;
D phase raw material:Glycerol caprylate 0.1%, basil oil 0.05%, 1,2- pentanediol 5%.
Preferably, the above-described anti-acne facial milk cleanser containing basil oil, the preparation method of described Tremella extract is: By Tremella with deionized water with weight 1:20 ~ 60 ratios mix, and soak 30 minutes, adjust pH value between 8.5 ~ 9.0, in 75 ~ 95 DEG C of extracting at constant temperature are after 4 ~ 6 hours, then use 200 ~ 300 mesh filtered through gauze at temperature is 40 ~ 50 DEG C, and filtering residue is again by above-mentioned side Method is extracted 2 times, three filtrates is merged, is stirred(Appropriate maltodextrin can be added), then it is concentrated into 20 DEG C relatively When density is 1.03~1.05, pH is 5 ~ 7, to be finally spray-dried(140 DEG C~200 DEG C of inlet temperature, 65 DEG C of leaving air temp~ 90 DEG C, flow be 150m1/h~1000m1/h), obtain Tremella extract;
The preparation method of Semen Coicis extract is:Semen Coiciss, plus the deionized water of 5~15 times of volumes of Semen Coiciss weight is weighed, Decocting and extract 3 times, after being heated to boiling, agitator is started once every half an hour, maintain fluidized state 1~4 hour, obtains Semen Coiciss Aqueous extract, crosses 100~400 mesh filter clothes, and filtering residue adds 4 again~water of 12 times of volumes, agitating heating, maintain fluidized state 1~3 Hour, take Semen Coiciss aqueous extract, cross 100~400 mesh filter clothes, filtering residue adds 4 again~water boiling and extraction of 12 times of volumes once, Merge three extracting solution, the Semen Coiciss concentrated solution of 20 DEG C of relative densities about 1. 0~1. 03 is concentrated into, is subsequently adding appropriate Beta-schardinger dextrin-or/and maltodextrin, after stirring, are spray-dried(110 DEG C~200 DEG C of inlet temperature, 50 DEG C of leaving air temp ~90 DEG C, flow be 150m1/h~1000m1/h), obtain Semen Coicis extract.
Described basil oil preparation method is for taking Herba Ocimi (Herba Ocimi Pilosi) herb, and the water of dosing material 6 ~ 15 times of volumes of weight, using water steaming Steam distillation method is extracted and is obtained.
Described Aloe extract is the extract of Ku Suola Aloe and Aloe ferox Miller, is day to sell product, meets 2005 Or 2010 Chinese Pharmacopoeia with regard to aloe barbadensis dried object quality standard.
Described basil oil preparation method is:Herba Ocimi (Herba Ocimi Pilosi) herb is taken, the water of dosing material 6 ~ 15 times of volumes of weight, using water steaming Steam distillation method is extracted and is obtained.
The raw material of the present invention, the basil oil has spasmolytic, sterilization, blood circulation promoting, aging resistance, treats acne, Rosemary Extract etc. is acted on;And have and refresh oneself, the effects such as improve functional disorder, stabilizing the emotions, anti-depression.
The Semen Coicis extract contains rich in protein and vitamin, and skin can be made delicate fine and smooth, eliminates mottle, So as to improve skin texture, color and luster and brightness.
The Tremella extract has moisturizing water lock, activation epidermis cell, repairs photo damaged skin, accelerates skin regeneration, The effects such as wrinkle-chasing wrinkle removing.
The glycyrrhizic acid dipotassium is used as anti-freckle agent, anti-allergic agent.
The Aloe extract has moisturizing, antiinflammatory, antibacterial, antipruritic, absorption ultraviolet, antiallergic, softening skin, anti-powder Multiple effects such as thorn, elimination superoxide radical, antiperspirant deodorant.Skin contraction, softness, moisturizing, antiinflammatory can be made, released firmly Change, keratinization, improve scar.
Contain a large amount of antioxidant in the oat kernel oil, free radical can be effectively removed, reduces free radical thin to skin The injury of born of the same parents, reduces wrinkle appearance, desalinates mottle;Can effectively remove and the general red phenomenon of the skin table for causing is irradiated by ultraviolet, to mistake Quick property skin has good nursing role.
Described hydrolysis Scleroglucan can help emulsion-stabilizing and control viscosity, improve stability, and also can in case Only pigment separated;The ratio of oil in formula can also be reduced, with the innate efficacy that releives with glabrous skin.
The angle Trionyx sinensis Wiegmann alkane can suppress the peroxidating of skin lipid, can effectively infiltrate through skin, and promote skin base cell Propagation, to delay skin aging, improving and eliminate chloasma all has obvious physiologic effect.
The glycerol caprylate is used as emulsifying agent.Polydimethylsiloxane has good skin moistening effect.Cetearyl alcohol Thickening agent as gentle high-quality.Glycerol has good moisture-keeping efficacy.1.3 Propylene Glycol have good moisture-keeping function.Poly- third Olefin(e) acid sodium is the thickening agent of high-quality.
The hyaluronate sodium can form thin film in skin surface, make skin produce good smooth feeling and moistening Sense;With scavenging activated oxygen, can promote the regeneration of injury skin, the supply of skin-nourishing and waste can be promoted Excretion, so as to prevent skin aging, plays face-nursing function;Hygroscopic capacity highest under low relative humidity (33%), and high relative Hygroscopic capacity under humidity (75%) is minimum, adapts to skin and is respectively provided with preferable moisturizing work under Various Seasonal, varying environment humidity With;Thickening and Stabilization can also be played.
The present invention in prescription screening, according to effect to be reached, selected multiple safely and effectively compositions, and in each group Divide on the basis of recommending consumption, by many experiments screening and multiple verification experimental verification, finally preferably obtain the place of this facial milk cleanser Side and preparation technology, above multiple active component Basil Essential, Aloe extract, oat kernel oil, Tremella extract, Semen Coiciss are carried After taking thing and base starting material scientific compatibility, stable performance, and the skin corium that independently directly can penetrate to the skin, it is easy to inhaled by skin Receive, can solve the problem that because the problems such as scytitiss that cause of clogging of pores, the colour of skin are obscure, has to preventing and treating the dermatosis such as acne Good effect.
The preparation method of basil oil anti-acne conditioning frost of the present invention, comprises the following steps:
(1) emulsifying pot, oil phase pot and water phase pot deionized water are cleaned, uses high-temperature steam sterilization;
(2) the A phase raw material described in claim 1 or 2 is added oil phase pot, stirring is warming up to 70~90 DEG C, makes material dissolution Mix homogeneously;
(3)The deionized water in the B phase raw material described in claim 1 or 2 and glycerol is weighed, is added in water phase pot, then by water After solution Scleroglucan, hyaluronate sodium, sodium polyacrylate are uniformly dispersed with appropriate 1,3-PD, and 1,3- of surpluses the third two Alcohol is together added in water phase pot, and stirring is warming up to 75~95 DEG C, makes material dissolution mix homogeneously;
(4) by emulsifying pot be heated to 80-90 DEG C standby;
(5) by step(3)Water phase pot raw material is pumped into step(4)In the emulsifying pot of heating, under stirring state, then by step(2) In oil phase pot raw material be pumped into step(4)In the emulsifying pot of heating, vacuum state stirring after finishing, is kept;Then by emulsifying pot High speed homogenization;
(6)Then 40~49 DEG C are cooled under stirring, emulsifying pot, then will be sweet in the C phase raw material described in claim 1 or 2 Oxalic acid dipotassium is together added in emulsifying pot with Semen Coicis extract, Tremella extract with after appropriate amount of deionized water dissolving, and stirring is equal Even, emulsifying;
(7) in the case of being kept stirring for, then the D phase raw material described in claim 1 or 2 is added in emulsifying pot, stirs;
(8) stirring and emulsifying pot is then proceeded to, 35~45 DEG C is cooled to, after the assay was approved filtering and discharging, fill, pack to obtain basil oil Anti-acne conditioning frost.
Preferably, the preparation method of above-described basil oil anti-acne conditioning frost, in step (5), emulsifying pot turns Speed is maintained at 25-35r/min.
Preferably, the preparation method of above-described basil oil anti-acne conditioning frost, it is characterised in that:Step (5) Middle processing condition is:Temperature is 73-77 DEG C, and the time is that 8-12 minute, speed controlling is in 2900-3100r/min.When homogenizing Temperature mainly affects mastic outward appearance, and temperature too low mastic emulsifying effectiveness is bad, the free energy of temperature too high increase system, reduces Emulsifier molecules are deteriorated in the absorption affinity of oil-water interfaces, emulsifying;In addition, temperature is too high can affect humidity.Mixing speed is too low, breast Change incomplete, it is impossible to homogenize well, affect paste stability and outward appearance;Mixing speed is too big, can bring bubble into, make cream Body seems uneven;Suitably mixing speed can just make the uniform emulsifying of mastic, and mastic outward appearance, stability and other character are just accorded with Close and require.The time effects that homogenize mastic outward appearance and thermostability, time too short mastic poor heat resistance, the time, oversize mastic viscosity became Little, stability is poor, is therefore homogenized the time using currently preferred, meets the requirements.
Preferably, the preparation method of above-described basil oil anti-acne conditioning frost, in step (6) during stirring and emulsifying Between be 18-22 minute, speed of agitator be 25-35r/min.
Preferably, the preparation method of above-described basil oil anti-acne conditioning frost, it is characterised in that step (7) In the speed of agitator that stirs be 13-17 minute 25-35r/min, the time.
Semen Coicis extract, Tremella extract and basil oil extracting method are ibid.
Beneficial effect:Compared to the prior art the basil oil anti-acne conditioning frost that the present invention is provided has advantages below:
The present invention passes through many experiments preferred feedstock, prepares and nurses one's health skin with good deep layer, and toxin expelling sterilizes, anti-acne, Speckle dispelling, crease-resistant, whitening, moist moisturizing, the basil oil anti-acne conditioning frost of promoting blood circulation to remove blood stasis and toxin expelling granulation promoting effect, present invention composition is former Material temperature and, have no toxic side effect, nonirritant, safety is good, especially has good prevention effect to dermatosis such as acnes.
Specific embodiment
The present invention is further elucidated with reference to specific embodiment, it should be understood that these embodiments be merely to illustrate the present invention and Restriction the scope of the present invention is not used in, after the present invention has been read, various equivalence shapes of the those skilled in the art to the present invention The modification of formula all falls within the application claims limited range.
Embodiment 1
1st, a kind of basil oil anti-acne conditioning frost, it is made up of the raw material of following percentage by weight:
A phase raw material:Angle Trionyx sinensis Wiegmann alkane 4kg, methyl sesquistearate 1.5kg, cetearyl alcohol 1.5kg, PEG-20 methyl Portugal Sugared sesquistearate 2kg, PEG-100 stearate 1kg, polydimethylsiloxane 1.5kg, 3 kg of Aloe extract, Herba bromi japonici Core oil 1kg;
B phase raw material:1,3- Propylene Glycol 4kg, glycerol 5kg, hydrolysis Scleroglucan 0.1kg, hyaluronate sodium 0.1kg, polyacrylic acid Sodium 0.5kg, deionized water 64.75kg;
C phase raw material:Semen Coicis extract 4kg, Tremella extract 0.5kg, glycyrrhizic acid dipotassium 0.4kg;
D phase raw material:Glycerol caprylate 0.1kg, basil oil 0.05kg, 1,2- pentanediol 5kg.
The preparation method of described Tremella extract is:By Tremella with deionized water with weight 1:60 ratios mix, and soak 30 minutes, between regulation pH value to 8.5, after 75 DEG C of extracting at constant temperature 4 hours, then with 200 mesh gauzes at temperature is 40 DEG C Filter, filtering residue is extracted 2 times again as stated above, three filtrates merged, is stirred, appropriate maltodextrin can be added, When being then concentrated into 20 DEG C of relative densities for 1.03, pH is finally to be spray-dried(140 DEG C of inlet temperature, 65 DEG C of leaving air temp, Flow is 150m1/h), obtain Tremella extract;
The preparation method of Semen Coicis extract is:Semen Coiciss, plus the deionized water of 10 times of volumes of Semen Coiciss weight is weighed, is decocted Extracting 3 times, after being heated to boiling, agitator is started once every half an hour, maintain fluidized state 2 hours, obtains Semen Coiciss water extraction Liquid, crosses 200 mesh filter clothes, and filtering residue adds the water of 8 times of volumes again, agitating heating, maintains fluidized state 2 hours, takes Semen Coiciss water extraction Take liquid, cross 200 mesh filter clothes, filtering residue again 6 times of volumes water boiling and extraction once, merge three extracting solution, be concentrated into 20 DEG C of phases Semen Coiciss concentrated solution to density about 1.0, is subsequently adding appropriate beta-schardinger dextrin-or/and maltodextrin, after stirring, spray Mist dries(150 DEG C of inlet temperature, 60 DEG C of leaving air temp, flow are 500m1/h), obtain Semen Coicis extract.
Described basil oil preparation method is for taking Herba Ocimi (Herba Ocimi Pilosi) herb, and the water of dosing material 10 times of volumes of weight, using vapor The way of distillation is extracted 2 hours and is obtained.
2nd, the preparation method of basil oil anti-acne conditioning frost, comprises the following steps:
(1) emulsifying pot, oil phase pot and water phase pot deionized water are cleaned, uses high-temperature steam sterilization;
(2) by 4kg angle Trionyx sinensis Wiegmann alkane, 1.5 kg methyl sesquistearates, 1.5 kg cetearyl alcohol, 2 kg first of PEG-20 Base glucose sesquistearate, 1 kg PEG-100 stearate, 1.5 kg polydimethylsiloxane, 3kg Aloe extract, 1 Kg oat kernel oil, adds the stirring of oil phase pot to be warming up to 80 DEG C, makes material dissolution mix homogeneously;
(3)Weigh 64.75kg deionized water and 5kg glycerol is added in water phase pot, then 0.1kg is hydrolyzed Scleroglucan, 0.1kg Hyaluronate sodium and 0.5kg sodium polyacrylate, after being uniformly dispersed with 0.5kg 1,3-PD, and 3.5kg 1,3-PD one With water phase pot is added, stirring is warming up to 85 DEG C, makes material body dissolve mix homogeneously.
(4) by emulsifying pot be heated to 85 DEG C standby;
(5) by water phase pot raw material suction emulsifying pot, again by oil phase pot raw material suction under stirring state (30 r/min), after finishing Keep vacuum(-0.05mpa)State is stirred(30 r/min)Emulsifying 20 minutes;
(6)Temperature is 75 DEG C, and speed controlling is in 3000r/min, homogenizing 10 minutes
(7) under stirring, (30 r/min) is slowly cooled to 45 DEG C, then by glycyrrhizic acid dipotassium with after 0.4kg deionized water dissolving, Together add emulsifying pot to stir with 4kg Semen Coicis extract, 0.5kg Tremella extract, stir 15 minutes, rotating speed is 30r/ min.
(8) it is kept stirring in situation (30 r/min), then D phase raw material addition emulsifying pot is stirred, stirs 15 minutes.
(9) continue stirring and 40 DEG C are cooled to, after the assay was approved filtering and discharging, record of weighing;
(10) sampling detection, fill, outsourcing, obtain product.
Embodiment 2
1st, a kind of basil oil anti-acne conditioning frost, it is made up of the raw material of following percentage by weight:
A phase raw material:Angle Trionyx sinensis Wiegmann alkane 2kg, methyl sesquistearate 1.2kg, cetearyl alcohol 1.3kg, PEG-20 methyl Portugal Sugared sesquistearate 1kg, PEG-100 stearate 0.5kg, polydimethylsiloxane 1kg, Aloe extract 1kg, Herba bromi japonici Core oil 0.5kg;
B phase raw material:1,3- Propylene Glycol 3kg, glycerol 3kg, hydrolysis Scleroglucan 0.08kg, hyaluronate sodium 0.08kg, polypropylene Sour sodium 0.2kg, deionized water 62kg;
C phase raw material:Semen Coicis extract 2kg, Tremella extract 0.3kg, glycyrrhizic acid dipotassium 0.2kg;
D phase raw material:Glycerol caprylate 0.08kg, basil oil 0.03kg, 1,2- pentanediol 3kg.
The preparation method of Semen Coicis extract is:Semen Coiciss, plus the deionized water of 15 times of volumes of Semen Coiciss weight is weighed, Decocting and extract 3 times, after being heated to boiling, agitator is started once every half an hour, maintain fluidized state 1~4 hour, obtains Semen Coiciss Aqueous extract, crosses 100 mesh filter clothes, and filtering residue adds the water of 8 times of volumes again, agitating heating, maintains fluidized state 2 hours, takes Semen Coiciss Core aqueous extract, crosses 100 mesh filter clothes, and filtering residue adds the water boiling and extraction of 6 times of volumes once again, merges three extracting solution, concentrates To the Semen Coiciss concentrated solution of 20 DEG C of relative densities about 1.03, appropriate beta-schardinger dextrin-or/and maltodextrin is subsequently adding, is stirred After mixing uniformly, it is spray-dried(170 DEG C of inlet temperature, 80 DEG C of leaving air temp, flow are 800m1/h), obtain Semen Coiciss extraction Thing.
Described basil oil preparation method is for taking Herba Ocimi (Herba Ocimi Pilosi) herb, and the water of dosing material 12 times of volumes of weight, using vapor The way of distillation is extracted 1.5 hours and is obtained.
2nd, the preparation method of basil oil anti-acne conditioning frost, comprises the following steps:
(1) emulsifying pot, oil phase pot and water phase pot deionized water are cleaned, uses high-temperature steam sterilization;
(2) by 2kg angle Trionyx sinensis Wiegmann alkane, 1.2 kg methyl sesquistearates, 1.3 kg cetearyl alcohol, PEG-20 1kg first Base glucose sesquistearate, 0.5kg PEG-100 stearate, 1 kg polydimethylsiloxane, 1kg Aloe extract, 0.5 kg oat kernel oil, adds the stirring of oil phase pot to be warming up to 75 DEG C, makes material dissolution mix homogeneously;
(3)Weigh 62kg deionized water and 3kg glycerol is added in water phase pot, then 0.08kg is hydrolyzed Scleroglucan, 0.08kg Hyaluronate sodium and 0.2kg sodium polyacrylate, after being uniformly dispersed with 0.5kg 1,3-PD, and 2.5kg 1,3-PD one With water phase pot is added, stirring is warming up to 80 DEG C, makes material body dissolve mix homogeneously.
(4) by emulsifying pot be heated to 90 DEG C standby;
(5) by water phase pot raw material suction emulsifying pot, again by oil phase pot raw material suction under stirring state (35 r/min), after finishing Keep vacuum(-0.05mpa)State is stirred(35 r/min)Emulsifying 22 minutes;
(6)Temperature is 80 DEG C, and speed controlling is in 2900r/min, homogenizing 12 minutes
(7) under stirring, (30 r/min) is slowly cooled to 45 DEG C, then by glycyrrhizic acid dipotassium with after 0.2kg deionized water dissolving, Together add emulsifying pot to stir with 2kg Semen Coicis extract, 0.3kg Tremella extract, stir 22 minutes, rotating speed is 30r/ min.
(8) it is kept stirring in situation (30 r/min), then D phase raw material addition emulsifying pot is stirred, stirs 15 minutes.
(9) continue stirring and 40 DEG C are cooled to, after the assay was approved filtering and discharging, record of weighing;
(10) sampling detection, fill, outsourcing, obtain product.
The white actual efficacy of 3 basil oil anti-acne of embodiment conditioning:
1. Miss Gao, 21 years old, using front, the long comedo of cheek was more than 1 year;Nursed one's health using 1 basil oil anti-acne of the embodiment of the present invention Frost, using once, after one month, comedo disappears, no pockmark, and face is pale, glossy, the toxic and side effects such as non-stimulated within 1 day, Follow-up 3 months, not long pox again.
2. Miss Wang, 28 years old, using front, the multiple place length of face had acne, and there is half a year the time, has acne print and has skin dark stain; Using 1 basil oil anti-acne of embodiment of the present invention conditioning frost, after one month, medicine for treating comedo skin dark stain of becoming estranged substantially subtracts using once within 1 day Weak, acne print disappears, skin smooth, Shui Run, white touched with red, the toxic and side effects such as non-stimulated, and follow-up 3 months is not recurred again.
3. Mr. Tang, 25 years old, using front, skin pore was thick, and the colour of skin is black, around the bridge of the nose and forehead length has comedo;Make With 2 basil oil anti-acne of embodiment of the present invention conditioning frost, using once, after one month, pox disappears, no pockmark within 1 day, skin exquisiteness, The toxic and side effects such as nonirritant, follow-up 3 months, long pox again, not very satisfied to this product.
4 activity experiment of embodiment
Through antioxidation and anti-pigmentation test result indicate that, the conditioning of basil oil anti-acne that the embodiment of the present invention 1 and 2 is prepared Frost has good antioxidation and anti-pigmentation.
Embodiment 5
The basil oil anti-acne conditioning frost for being prepared using the embodiment of the present invention 1 is applied to 30 sensitive skin persons, experimental result Show, continuous using 4 weeks, only 2 slight stimulation allergy occur, show no obvious irritation, can receive.
The above is only the preferred embodiment of the present invention, it is noted that come for those skilled in the art Say, under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be regarded as Protection scope of the present invention.

Claims (8)

1. a kind of basil oil anti-acne conditioning is white, it is characterised in that it is made up of the raw material of following percentage by weight:
A phase raw material:Angle Trionyx sinensis Wiegmann alkane 2-7%, methyl sesquistearate 1.2-1.8%, cetearyl alcohol 1.3-1.7%, PEG-20 Methyl sesquistearate 1-4%, PEG-100 stearate 0.5-1.5%, polydimethylsiloxane 1-3%, Aloe are extracted Thing 1-5%, oat kernel oil 0.5-1.5%;
B phase raw material:1,3- Propylene Glycol 3-8%, glycerol 3-7%, hydrolysis Scleroglucan 0.08-0.14%, hyaluronate sodium 0.08- 0.13%th, sodium polyacrylate 0.2-0.8%, deionized water 62-68%;
C phase raw material:Semen Coicis extract 2-6%, Tremella extract 0.3-0.7%, glycyrrhizic acid dipotassium 0.2-0.6%;
D phase raw material:Glycerol caprylate 0.08-0.14%, basil oil 0.03-0.08%, 1,2- pentanediol 3-8%.
2. basil oil anti-acne conditioning according to claim 1 is white, it is characterised in that it is by the raw material of following percentage by weight Make:
A phase raw material:Angle Trionyx sinensis Wiegmann alkane 4%, methyl sesquistearate 1.5%, cetearyl alcohol 1.5%, PEG-20 methyl Sesquistearate 2%, PEG-100 stearate 1%, polydimethylsiloxane 1.5%, 3 % of Aloe extract, oat kernel oil 1%;
B phase raw material:1,3- Propylene Glycol 4%, glycerol 5%, hydrolysis Scleroglucan 0.1%, hyaluronate sodium 0.1%, sodium polyacrylate 0.5%th, deionized water 64.75%;
C phase raw material:Semen Coicis extract 4%, Tremella extract 0.5%, glycyrrhizic acid dipotassium 0.4%;
D phase raw material:Glycerol caprylate 0.1%, basil oil 0.05%, 1,2- pentanediol 5%.
3. basil oil anti-acne conditioning according to claim 1 and 2 is white, it is characterised in that the preparation side of Semen Coicis extract Method is:Semen Coiciss, plus the deionized water of 5~15 times of volumes of Semen Coiciss weight is weighed, is decocted and extract 3 times, after being heated to boiling, per Agitator being started once every half an hour, maintain fluidized state 1~4 hour, obtain Semen Coiciss aqueous extract, crosses the filter of 100~400 mesh Cloth, filtering residue adds 4 again~water of 12 times of volumes, agitating heating, maintain fluidized state 1~3 hour, Semen Coiciss aqueous extract is taken, Cross 100~400 mesh filter clothes, filtering residue adds 4 again~water boiling and extraction of 12 times of volumes once, merge three extracting solution, be concentrated into The Semen Coiciss concentrated solution of 20 DEG C of relative densities about 1. 0~1. 03, is subsequently adding appropriate beta-schardinger dextrin-or/and Fructus Hordei Germinatus paste Essence, after stirring, is spray-dried, obtains Semen Coicis extract.
The preparation method of described Tremella extract is:By Tremella with deionized water with weight 1:20 ~ 60 ratios mix, and soak 30 Minute, between regulation pH value to 8.5 ~ 9.0, after 75 ~ 95 DEG C of extracting at constant temperature 4 ~ 6 hours, then use at temperature is 40 ~ 50 DEG C 200 ~ 300 mesh filtered through gauze, filtering residue is extracted 2 times again as stated above, three filtrates is merged, is stirred, be then concentrated into When 20 DEG C of relative densities are 1.03~1.05, pH is 5 ~ 7, to be finally spray-dried, obtain Tremella extract;
Described basil oil preparation method is:Herba Ocimi (Herba Ocimi Pilosi) herb is taken, the water of dosing material 6 ~ 15 times of volumes of weight, using vapor steaming Evaporate method extraction to be obtained.
4. the basil oil anti-acne described in claim 1 or 2 nurses one's health the preparation method of frost, it is characterised in that comprise the following steps:
(1) emulsifying pot, oil phase pot and water phase pot deionized water are cleaned, uses high-temperature steam sterilization;
(2) the A phase raw material described in claim 1 or 2 is added oil phase pot, stirring is warming up to 70~90 DEG C, makes material dissolution Mix homogeneously;
(3)The deionized water in the B phase raw material described in claim 1 or 2 and glycerol is weighed, is added in water phase pot, then by water After solution Scleroglucan, hyaluronate sodium, sodium polyacrylate are uniformly dispersed with appropriate 1,3-PD, and 1,3- of surpluses the third two Alcohol is together added in water phase pot, and stirring is warming up to 75~95 DEG C, makes material dissolution mix homogeneously;
(4) by emulsifying pot be heated to 80-90 DEG C standby;
(5) by step(3)Water phase pot raw material is pumped into step(4)In the emulsifying pot of heating, under stirring state, then by step(2) In oil phase pot raw material be pumped into step(4)In the emulsifying pot of heating, vacuum state stirring after finishing, is kept;Then by emulsifying pot High speed homogenization;
(6)Then 40~49 DEG C are cooled under stirring, emulsifying pot, then will be sweet in the C phase raw material described in claim 1 or 2 Oxalic acid dipotassium is together added in emulsifying pot with Semen Coicis extract, Tremella extract with after appropriate amount of deionized water dissolving, and stirring is equal Even, emulsifying;
(7) in the case of being kept stirring for, then the D phase raw material described in claim 1 or 2 is added in emulsifying pot, stirs;
(8) stirring and emulsifying pot is then proceeded to, 35~45 DEG C is cooled to, after the assay was approved filtering and discharging, fill, pack to obtain basil oil Anti-acne conditioning frost.
5. a basil oil anti-acne according to claim 4 nurses one's health the preparation method of frost, it is characterised in that breast in step (5) The rotating speed for changing pot is maintained at 25-35r/min.
6. basil oil anti-acne according to claim 4 nurses one's health the preparation method of frost, it is characterised in that:Homogenizing in step (5) Condition is:Temperature is 73-77 DEG C, and the time is that 8-12 minute, speed controlling is in 2900-3100r/min.
7. basil oil anti-acne according to claim 4 nurses one's health the preparation method of frost, it is characterised in that:Stirring in step (6) Emulsification times are 18-22 minute, and speed of agitator is 25-35r/min.
8. basil oil anti-acne according to claim 4 nurses one's health the preparation method of frost, it is characterised in that stirring in step (7) It is 13-17 minute 25-35r/min, the time that uniform speed of agitator is.
CN201610960622.8A 2016-11-04 2016-11-04 Basil oil acne-removing regulating cream and preparation method thereof Pending CN106420526A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107802535A (en) * 2017-11-14 2018-03-16 欧诗漫生物股份有限公司 Purple bamboo shoot tea skin care face cream and preparation method thereof
KR20230038964A (en) * 2021-09-13 2023-03-21 ㈜닥터솔루션 composition

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Publication number Priority date Publication date Assignee Title
CN1078644A (en) * 1993-03-15 1993-11-24 青岛市第二人民医院 Basil cream and manufacturing process thereof and purposes
CN102885755A (en) * 2011-07-22 2013-01-23 海南医学院 Basil facial mask and preparation method thereof
CN103060096A (en) * 2011-10-24 2013-04-24 海南医学院 Extraction method of basil plant volatile oi
CN103432037A (en) * 2013-08-24 2013-12-11 上海艳紫化工科技有限公司 Clove basil oil skin cream

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1078644A (en) * 1993-03-15 1993-11-24 青岛市第二人民医院 Basil cream and manufacturing process thereof and purposes
CN102885755A (en) * 2011-07-22 2013-01-23 海南医学院 Basil facial mask and preparation method thereof
CN103060096A (en) * 2011-10-24 2013-04-24 海南医学院 Extraction method of basil plant volatile oi
CN103432037A (en) * 2013-08-24 2013-12-11 上海艳紫化工科技有限公司 Clove basil oil skin cream

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107802535A (en) * 2017-11-14 2018-03-16 欧诗漫生物股份有限公司 Purple bamboo shoot tea skin care face cream and preparation method thereof
CN107802535B (en) * 2017-11-14 2020-07-24 欧诗漫生物股份有限公司 Skin-care face cream containing purple bamboo shoot and tea and preparation method of skin-care face cream
KR20230038964A (en) * 2021-09-13 2023-03-21 ㈜닥터솔루션 composition
KR102575645B1 (en) * 2021-09-13 2023-09-07 (주)닥터솔루션 composition

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Application publication date: 20170222