CN106526203A - 一种用于左半结肠癌检测的试剂盒 - Google Patents
一种用于左半结肠癌检测的试剂盒 Download PDFInfo
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- G—PHYSICS
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
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Abstract
Description
名称 | 解离常数Kd(单位nM) |
KLK6-1 | 8.7 |
KLK6-2 | 8.9 |
KLK6-3 | 10.5 |
KLK6-4 | 11.3 |
KLK6-5 | 12.5 |
KLK6-6 | 7.9 |
KLK6-7 | 14.6 |
KLK6-8 | 16.7 |
KLK6-9 | 15.0 |
KLK6-10 | 9.3 |
KLK6-11 | 8.4 |
KLK6-12 | 10.0 |
KLK6-13 | 11.4 |
KLK6-14 | 8.9 |
KLK6-15 | 12.5 |
KLK6-16 | 13.4 |
BB缓冲液空白对照 | 无结合能力 |
Claims (5)
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CN201611031356.7A CN106526203B (zh) | 2016-11-22 | 2016-11-22 | 一种用于左半结肠癌检测的试剂盒 |
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CN201611031356.7A CN106526203B (zh) | 2016-11-22 | 2016-11-22 | 一种用于左半结肠癌检测的试剂盒 |
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Publication Number | Publication Date |
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CN106526203A true CN106526203A (zh) | 2017-03-22 |
CN106526203B CN106526203B (zh) | 2018-10-09 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111936858A (zh) * | 2019-04-04 | 2020-11-13 | 清华大学 | 一种胃癌极早期细胞标志和胃癌前病变早期细胞标志及其在诊断试剂盒中的应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009057849A1 (en) * | 2007-10-30 | 2009-05-07 | Korea Research Institute Of Bioscience And Biotechnology | Colon cancer diagnostic markers using up-regulated genes |
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2016
- 2016-11-22 CN CN201611031356.7A patent/CN106526203B/zh active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009057849A1 (en) * | 2007-10-30 | 2009-05-07 | Korea Research Institute Of Bioscience And Biotechnology | Colon cancer diagnostic markers using up-regulated genes |
Non-Patent Citations (1)
Title |
---|
TEVE ARNOLD等: "One round of SELEX for the generation of DNA aptamers directed against KLK6", 《BIOL. CHEM.》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111936858A (zh) * | 2019-04-04 | 2020-11-13 | 清华大学 | 一种胃癌极早期细胞标志和胃癌前病变早期细胞标志及其在诊断试剂盒中的应用 |
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