CN106511911A - Traditional Chinese medicine patch for treating coronary heart disease and preparation method thereof - Google Patents

Traditional Chinese medicine patch for treating coronary heart disease and preparation method thereof Download PDF

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CN106511911A
CN106511911A CN201611258306.2A CN201611258306A CN106511911A CN 106511911 A CN106511911 A CN 106511911A CN 201611258306 A CN201611258306 A CN 201611258306A CN 106511911 A CN106511911 A CN 106511911A
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parts
root
chinese medicine
application agent
herbal application
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刘永祥
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Changxin Huzhou Yi Jian Medical Technology Co Ltd
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Changxin Huzhou Yi Jian Medical Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins

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Abstract

The invention discloses a traditional Chinese medicine patch for treating coronary heart disease. The traditional Chinese medicine patch is prepared mainly from the following traditional Chinese medicinal materials in parts by weight: 210-230 parts of root of kudzu vine, 180-200 parts of root of red-rooted salvia, 130-150 parts of rhizoma alismatis, 140-160 parts of leonurus, 210-230 parts of pubescent holly root, 140-160 parts of pseudo-ginseng, 90-110 parts of cassia twig, 130-150 parts of common burreed rhizome, 130-150 parts of curcuma zedoary, 110-130 parts of chrysanthemum morifolium, 90-110 parts of rhizoma menispermi, 130-150 parts of hawthorn, 130-150 parts of radix stephaniae tetrandrae, 130-150 parts of ligusticum wallichii, 90-110 parts of red flowers and 90-110 parts of cinnamon. In addition, the invention also discloses a preparation method of the traditional Chinese medicine patch. Under the synergic effect of various medicines, various vascular lesions can be gradually repaired, blood circulation can be improved and normal cardiovascular functions can be recovered.

Description

It is a kind of to treat herbal application agent of coronary heart disease and preparation method thereof
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of herbal application agent for treating coronary heart disease and its preparation side Method.
Background technology
Coronary heart disease is the abbreviation of coronary atherosclerotic heart disease, refers to the coronary artery of supply cardiotrophin material There is serious atherosis or spasm, make coronary artery stenosis or blocking, and the obliteration that thrombosis is caused, cause the heart A kind of heart disease of myocardial ischemia anoxic or infraction, also known as ischemic heart disease.Coronary heart disease is that atherosclerotic causes organopathy The most common type of change, is the common disease of harm the elderly's health, and rejuvenation tendency is presented.The reason for coronary artery narrows exists In:The long-term too high, cholesterol of blood fat in blood is deposited on the inner membrance of coronary artery tube chamber with accumulating over a long period, and forms ground pattern Patch, make that the inner membrance of otherwise smooth becomes are coarse, and soft tube wall becomes stiff, and on this basis, the blood platelet of rupture also coagulates Poly- adhesion is got on, and then just as river course is by mud blocking, makes coronary lumen narrow, or even entirely shuts.Coronary artery it is not smooth Even entirely shut, cause myocardial blood supply bad, cardiac muscle cannot get the nutrition of blood and necrosis is referred to as myocardial infarction, and this is coronary disease The performance of sick most serious.Once myocardium large area infarct, if quickly can not eliminating again, then the life of people also just finishes.
Coronary heart disease mostly is asthenia in origin and asthenia in superficiality, and this void is marked actually based on heart arteries and veins stasis blocking based on the deficiency of vital energy, and the deficiency of vital energy is then difficult row Blood, makes hematogenous blockage, causes heart vessel blockage stasis, heart row mistake degree, the heart to become homeless foster, and with the passing of time the course of disease, causes to stop in hemostasis, and asthenia of qi and blood declines, Performance symptom has arrhythmia cordis, angina pectoris, miocardial infarction, heart failure etc., and vicious circle.
Drug therapy such as nitric acid lipid, anti-platelet agent etc. medicine is typically adopted at present clinically, major part is all It is to need lifelong medication to control.Severe case's operative treatment is put up a bridge with coronary arteries or PCI mounting bracket, and heart rises Fight the methods such as device, so only made physics and sexually revised, and also needed Long-term taking medicine to maintain.Oral drugs have either large or small pair Effect, as antiarrhythmic medicine, while anti-arrhythmia, itself also has and causes ARR side effect, and Taboo is many, and Long-Time Service can cause drug resistance, and so as to escalated dose of having to, this more causes the generation of side effect, in addition Increasing drug dose makes drug toxicity in a large number in people's cylinder accumulation, and function is damaged.Operative treatment and PCI Although having cured local lesion, plugged after the several years of curing the symptoms, not the disease again, also simultaneously human body is integrally caused greatly Injury.Chinese traditional treatment coronary heart disease has prescriptions and the method such as acupuncture-moxibustion, massage of many classics, but to critically ill patient and man at an advanced age Therapeutic effect difference risk is high.
Theory of traditional Chinese medical science thinks:Human body be one centered on internal organs, get in touch with channels and collaterals, essence, gas, blood, god high unity body. The sole of the mankind is most flourishing in animal, and it is the passage for running qi and blood that it has abundant blood vessel and nerve, blood vessel and nerve, If human vas, channels and collaterals are unobstructed, vital essence is abundant, equilibrium between yin and yang, Metabolism of Normal will not generally occur disease, if Circulation is obstructed then, and All kinds of diseases and ailments break out.It is to affect circulation, the major reason of metabolic function that the stagnation of the circulation of vital energy, blood stasis, wet (phlegm) product, poison are poly-, is being controlled When treating illness, it is circulation, the metabolic function for how improving, repairing human body first.Have in 12 channels and collaterals of human body six directly with Foot is connected, and each internal organs organ of human body has its corresponding echo area in foot, can be taken by stimulating these echo areas To the regulation of qi and blood, coordinate the effect of internal organs, Yin Yang balancing, the Yongquan acupoint in vola is that the kidney channel of foot-Shaoyin wants cave, is body discharges The passage of the turbid gas of disease.《The Yellow Emperor's Canon of Internal Medicine》Middle theory:" kidney is for spring, spring person sole center." kidney be the congenital foundation, vigour it Root, thus Yongquan acupoint human health-preserving, diseases prevention, cure the disease, the various aspects such as health care show its important function.
The content of the invention
To achieve these goals, the present invention is proposed and a kind of treats herbal application agent of coronary heart disease and preparation method thereof.
A kind of herbal application agent for treating coronary heart disease, described herbal application agent is mainly by the Chinese medicine of following weight proportioning Make:210~230 parts of the root of kudzu vine, 180~200 parts of the red sage root, 130~150 parts of rhizoma alismatis, 140~160 parts of motherwort, ilex pubescens 210 ~230 parts, 140~160 parts of pseudo-ginseng, 90~110 parts of cassia twig, 130~150 parts of Rhizoma Sparganii, 130~150 parts of curcuma zedoary, FLOS CHRYSANTHEMI ALBA from Haizhou of China 110 ~130 parts, 90~110 parts of rhizoma menispermi, 130~150 parts of hawthorn, 130~150 parts of tetrandra root, 130~150 parts of Ligusticum wallichii, safflower 90~ 110 parts, 90~110 parts of Chinese cassia tree.
Further preferably, described herbal application agent is made up of the Chinese medicine of following weight proportioning:220 parts of the root of kudzu vine, cassia twig 100 parts, 130 parts of Rhizoma Sparganii, 130 parts of curcuma zedoary, 190 parts of the red sage root, 140 parts of rhizoma alismatis, 120 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 150 parts of motherwort, ilex pubescens 220 parts, 100 parts of rhizoma menispermi, 140 parts of hawthorn, 140 parts of tetrandra root, 140 parts of Ligusticum wallichii, 100 parts of safflower, 90 parts of Chinese cassia tree, 150 parts of pseudo-ginseng, In the preferred scope, drug effect is optimal.
Further preferably, described herbal application agent is made up of the Chinese medicine of following weight proportioning:230 parts of the root of kudzu vine, cassia twig 90 parts, 150 parts of Rhizoma Sparganii, 130 parts of curcuma zedoary, 200 parts of the red sage root, 130 parts of rhizoma alismatis, 130 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 140 parts of motherwort, ilex pubescens 230 parts, 90 parts of rhizoma menispermi, 150 parts of hawthorn, 130 parts of tetrandra root, 150 parts of Ligusticum wallichii, 90 parts of safflower, 110 parts of Chinese cassia tree, 140 parts of pseudo-ginseng.
Further preferably, described herbal application agent is made up of the Chinese medicine of following weight proportioning:210 parts of the root of kudzu vine, cassia twig 110 parts, 130 parts of Rhizoma Sparganii, 150 parts of curcuma zedoary, 180 parts of the red sage root, 150 parts of rhizoma alismatis, 110 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 160 parts of motherwort, ilex pubescens 210 parts, 110 parts of rhizoma menispermi, 130 parts of hawthorn, 150 parts of tetrandra root, 130 parts of Ligusticum wallichii, 110 parts of safflower, 90 parts of Chinese cassia tree, 160 parts of pseudo-ginseng.
Present invention also offers a kind of preparation method of the herbal application agent of above-mentioned treatment coronary heart disease, specially:By the root of kudzu vine, Cassia twig, Rhizoma Sparganii, curcuma zedoary, the red sage root, rhizoma alismatis, FLOS CHRYSANTHEMI ALBA from Haizhou of China, motherwort, ilex pubescens, rhizoma menispermi, hawthorn, tetrandra root, Ligusticum wallichii, safflower, Chinese cassia tree With pseudo-ginseng decontamination, herb powder of the mixed grinding into 150~200 mesh by weight ratio after drying sterilizing, gained Chinese medicine Powder adds auxiliary material, and at 45~80 DEG C, heating stirring makes the herbal application agent.
Preferably, the auxiliary material is made up of the Chinese medicine of following weight proportioning:600~620 parts of sesame oil, glycerine 440~ 460 parts, 400~420 parts of vaseline, 580~600 parts of lanolin.
Further preferably, the auxiliary material is made up of the Chinese medicine of following weight proportioning:It is 620 parts of sesame oil, 460 parts of glycerine, all 420 parts of intellectual circle, 580 parts of lanolin.
The present invention passes through medicament plaster on human foot Yongquan acupoint, and herbal application agent is directly contacted with skin, is passed through Transdermal absorption, the conduction of channels and collaterals, the regulation of body fluid, the reflection of nerve, while therapeutic action is reached, improve body tissue's device The physiological function of official, strengthens immunity of organisms, is repaired the various physiological functions of human body, and dosage is few, easy to use, Jing Ji material benefit, and therapeutic process hurtless measure, no pain, have no side effect, meet humane treatment.
Preferably, heating plate is configured outside herbal application agent, above-mentioned heating plate can pass through heating wire, the electricity arranged in which Magnetic coil, pct heaters, resistance, electronic component, semiconductor heating plate etc. and other physical heating modes are heated.Heat is A kind of physical agent, it is the flesh muscle that can relax, loose reason, promoting blood circulation and removing obstruction in channels, stimulated by the warm of herbal fomentation, local blood can be caused Enlargement of pipe, stimulates circulation, and improves metabolism, accelerates the recovery from illness of disease, obtains the effect got twice the result with half the effort.
Crude drug of the present invention is described in detail below:
The root of kudzu vine:Expelling pathogenic factors from muscles and skin promotes the production of body fluid, rise carry yang-energy, expansion of blood vessels, increase coronary flow, reduce myocardial oxygen consumption, reduction blood fat, Blood sugar, blood pressure;
Cassia twig:Warming meridian, supporing yang, expelling pathogenic factors from muscles and skin, expansion of blood vessels, anti-inflammatory;
Rhizoma Sparganii, curcuma zedoary:Blood-breaking, Xiao Ji Zhi Tong, antithrombotic;
The red sage root:Invigorate blood circulation, dissolving stasis, clear away heart-fire, coronary artery dilating, flow increasing;
Rhizoma alismatis:Slightly sweet flavor cold in nature, returns kidney, bladder warp, and clearing damp and promoting diuresis, heat-clearing benefit are cloudy, reducing blood lipid, reduce serum cholesterol;
FLOS CHRYSANTHEMI ALBA from Haizhou of China:With only dysentery, anti-inflammatory, improving eyesight, step-down, lipid-loweringing, the effect of salubrity;
Motherwort:Promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, suppression platelet aggregation, antithrombotic;
Ilex pubescens:Blood circulation and channel invigorating, clearing heat and detoxicating, coronary dilatation, flow increasing, enhancing myocardial contractive power, reduce serum cholesterol, reduction Triglycerides;
Rhizoma menispermi:Clearing heat and detoxicating, swelling and pain relieving, reduce blood pressure, coronary dilatation flow increasing, anti-arrhythmia, antibacterial;
Hawthorn:Promoting the circulation of qi disappear the stasis of blood, cardiac stimulant, flow increasing, hypotensive, blood fat;
Tetrandra root:Inducing diuresis for removing edema, wind-expelling pain-stopping, step-down, expansion myocardial ischemia, anti-ventricular hypertrophy;
Ligusticum wallichii:Blood-activating and qi-promoting, wind-expelling pain-stopping, flow increasing, calmness, improve myocardial oxygen delivery;
Safflower:Invigorate blood circulation, blood stasis removing analgesic, coronary dilatation flow increasing, anticoagulation, calmness, anti-inflammatory;
Chinese cassia tree:Mends fire supporing yang, eliminating cold to stop pain, invigorate blood circulation, step-down, coronary dilatation, increasing leucocyte, antithrombus formation;
Pseudo-ginseng:Dissipate stasis of blood hemostasis, detumescence ding-tong, increasing are preced with flow, suppress platelet aggregation, reduce blood viscosity, reduce blood pressure Blood fat, enhance immunity.
The invention has the advantages that:
Herbal application agent of the present invention is applied on Human Sole Yongquan acupoint, outer additional backing, due to directly contacting with skin, By Transdermal absorption, warming meridian, mends fire supporing yang, eliminating cold to stop pain, expansion of blood vessels, invigorate blood circulation, scattered stasis of blood wind-dispelling, coronary dilatation increasing are played Stream, anti-inflammation, dissolving stasis blood, anticoagulation, inducing diuresis for removing edema, increasing leucocyte, antithrombus formation, anti-arrhythmia, expand myocardial ischemia, Anti- ventricular hypertrophy;Promoting the circulation of qi disappear the stasis of blood, cardiac stimulant, hypotensive, blood fat;The various pathologies of blood vessel are progressively repaired, improves blood circulation, recovered Cardiovascular normal function.
Specific embodiment
Embodiment 1
A kind of herbal application agent for treating coronary heart disease, is made up of the Chinese medicine of following weight proportioning:220 parts of the root of kudzu vine, cassia twig 100 parts, 130 parts of Rhizoma Sparganii, 130 parts of curcuma zedoary, 190 parts of the red sage root, 140 parts of rhizoma alismatis, 120 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 150 parts of motherwort, ilex pubescens 220 parts, 100 parts of rhizoma menispermi, 140 parts of hawthorn, 140 parts of tetrandra root, 140 parts of Ligusticum wallichii, 100 parts of safflower, 90 parts of Chinese cassia tree, 150 parts of pseudo-ginseng.
Method of preparation and use:By above-mentioned Chinese medicine decontamination, after drying sterilizing, by weight ratio mixed grinding into The powder of 150~200 mesh, gained Chinese medicine powder add 680 parts of sesame oil, 400 parts of glycerine, 380 parts of vaseline, 620 parts of lanolin, At 55 DEG C, heating stirring makes the herbal application agent.Gained herbal application agent is directly applied at human foot Yongquan acupoint, More renew within 24 hours patch, be within 30 days a course for the treatment of.
Embodiment 2
A kind of herbal application agent for treating coronary heart disease, is made up of the Chinese medicine of following weight proportioning:230 parts of the root of kudzu vine, cassia twig 90 parts, 150 parts of Rhizoma Sparganii, 130 parts of curcuma zedoary, 200 parts of the red sage root, 130 parts of rhizoma alismatis, 130 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 140 parts of motherwort, ilex pubescens 230 parts, 90 parts of rhizoma menispermi, 150 parts of hawthorn, 130 parts of tetrandra root, 150 parts of Ligusticum wallichii, 90 parts of safflower, 110 parts of Chinese cassia tree, 140 parts of pseudo-ginseng.
Method of preparation and use:By above-mentioned Chinese medicine decontamination, after drying sterilizing, by weight ratio mixed grinding into The powder of 150~200 mesh, gained Chinese medicine powder add 650 parts of sesame oil, 420 parts of glycerine, 400 parts of vaseline, 610 parts of lanolin, At 65 DEG C, heating stirring makes the herbal application agent.Gained herbal application agent is directly applied at human foot Yongquan acupoint, More renew within 24 hours patch, be within 30 days a course for the treatment of.
Embodiment 3
A kind of herbal application agent for treating coronary heart disease, is made up of the Chinese medicine of following weight proportioning:210 parts of the root of kudzu vine, cassia twig 110 parts, 130 parts of Rhizoma Sparganii, 150 parts of curcuma zedoary, 180 parts of the red sage root, 150 parts of rhizoma alismatis, 110 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 160 parts of motherwort, ilex pubescens 210 parts, 110 parts of rhizoma menispermi, 130 parts of hawthorn, 150 parts of tetrandra root, 130 parts of Ligusticum wallichii, 110 parts of safflower, 90 parts of Chinese cassia tree, 160 parts of pseudo-ginseng.
Method of preparation and use:By above-mentioned Chinese medicine decontamination, after drying sterilizing, by weight ratio mixed grinding into The powder of 150~200 mesh, gained Chinese medicine powder add 650 parts of sesame oil, 430 parts of glycerine, 410 parts of vaseline, 600 parts of lanolin, At 50 DEG C, heating stirring makes the herbal application agent.Gained herbal application agent is directly applied at human foot Yongquan acupoint, More renew within 24 hours patch, be within 30 days a course for the treatment of.
Embodiment 4
A kind of herbal application agent for treating coronary heart disease, is made up of the Chinese medicine of following weight proportioning:225 parts of the root of kudzu vine, cassia twig 90 parts, 145 parts of Rhizoma Sparganii, 130 parts of curcuma zedoary, 180 parts of the red sage root, 145 parts of rhizoma alismatis, 110 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 160 parts of motherwort, ilex pubescens 220 parts, 110 parts of rhizoma menispermi, 140 parts of hawthorn, 145 parts of tetrandra root, 130 parts of Ligusticum wallichii, 105 parts of safflower, 90 parts of Chinese cassia tree, 150 parts of pseudo-ginseng.
Method of preparation and use:By above-mentioned Chinese medicine decontamination, after drying sterilizing, by weight ratio mixed grinding into The powder of 150~200 mesh, gained Chinese medicine powder add 620 parts of sesame oil, 460 parts of glycerine, 420 parts of vaseline, 580 parts of lanolin, The herbal application agent is made in 80 DEG C of heating stirrings.Gained herbal application agent is directly applied at human foot Yongquan acupoint, and 24 Hour more renews patch, is within 30 days a course for the treatment of.
Curative effect determinate standard:
It is effective:The cardinal symptoms such as angina pectoris disappear or reach effective standard, and electrocardiogram recovers to normal ECG or reaches It is substantially normal (i.e. normal range (NR) electrocardiogram).Effectively:The disappearance of the cardinal symptoms such as angina pectoris reaches effective standard, and electrocardiogram improves Reach effective standard.It is invalid:, without improvement, electrocardiogram is substantially identical with before treatment for the cardinal symptoms such as angina pectoris.Sentence in comprehensive therapeutic effect When disconnected, if the cardinal symptom such as angina pectoris curative effect is inconsistent with both ECG curative effects, should be with the low result of curative effect as comprehensive treatment Effect.
General clinical data:Clinical observation case totally 200, the herbal application agent prepared using the embodiment of the present invention 1 are treated Effect see the table below:
As shown in Table 1, clinical observation case of the present invention 200, the herbal application agent prepared using the embodiment of the present invention 1 Directly application more renews patch for 24 hours at human foot Yongquan acupoint, is within 30 days a course for the treatment of.After one course for the treatment of of treatment, curative effect As a result it is:Effective 121,60.5% is accounted for, effective 77,38.5% is accounted for, invalid 2, is accounted for 1%, total effective rate 99%.The present invention Herbal application agent is applied on Human Sole Yongquan acupoint, outer additional backing, due to directly contacting with skin, by Transdermal absorption, Play warming meridian, mends fire supporing yang, eliminating cold to stop pain, expansion of blood vessels, invigorate blood circulation, dissipate stasis of blood wind-dispelling, coronary dilatation flow increasing, anti-inflammation, Dissolving stasis blood, anticoagulation, inducing diuresis for removing edema, increasing leucocyte, antithrombus formation, anti-arrhythmia, expansion myocardial ischemia, anti-ventricular hypertrophy; Promoting the circulation of qi disappear the stasis of blood, cardiac stimulant, hypotensive, blood fat;The various pathologies of blood vessel are progressively repaired, improves blood circulation, recovery is cardiovascular just Chang Gongneng, is adapted to marketing drugs and promotes.
Model case
Case 1
Liu so-and-so, man, 80 years old, Shanghai retired veteran cadre, Jing examination in hospital, patient's sinus rhythm severe cardiac delayed (heart rate 38 Jump/minute), early rich, atrial fibrillation, atrial expansion, expert advice are first installed heart heartstart and are nursed one's health with medicine again.Due to working as old man 80 years old advanced age, body are very weak, and pacemaker also brings along other side effects in addition, therefore peace of being unwilling in person Dress, applies vola Yongquan acupoint with herbal application agent afterwards, and after 30 days, symptom is substantially eliminated, and heart rate returns to or so 60 jumps/minute.With Health care is carried out with the herbal application agent application vola every year afterwards, is also still living and in good health so far, annual health check-up cardiovascular diseases index is basically reached Health requirements.And cardiovascular drugs were not taken over more than ten years.
Case 2
Chen, man, 68 years old, due to checking UP to hospital after multiple faintness, 24 hr Ambulatory EKG Monitorings showed, Fang Xing Premature beat 34 times, single 31 times, short battle array room speed 1 time, VPB 12105 times, single 11834 times, bigeminy 4750 times, in pairs It is 130 times, more than 2.0 seconds intervals 39 times, most long 2.3 seconds, it is diagnosed as (1) sinus rhythm, (2) frequent premature ventricular beatss, is in partly two Connection rule, (3) two degree of I type atrioventricular block, (4) Left ventricular hypervoltage V5-6ST sections are forced down.Vola is applied using herbal application agent Yongquan acupoint after 30 days (course for the treatment of) symptom of not relaxing substantially eliminate, period do not took medicine, without other any treatment hands Section.Interval reuses herbal application agent after 1 year and carries out health care in 30 days, shows during further consultation:Room morning sum is reduced to 266 accountings 0.32%, room morning bigeminy is reduced to 26 times, atrial premature beats 7 times, has no that Left ventricular hypervoltage V5-6ST sections are forced down and hinders with Atrioventricular Conduction The symptom such as stagnant.
Case 3
Money so-and-so, female, 84 years old, careful electrograph showed and is diagnosed as sinus bradycardia (40 beats/min), II degree I type chambers Block, T ripples change, cardiac electric axis severe left avertence, the right beam branch block of imperfection.Using herbal application agent of the present invention 30 My god, during further consultation, heart rate returns to 67 beats/min, has no II degree I type atrioventricular blocks, and T ripples change, cardiac electric axis severe left avertence etc. Symptom, during this period without other any treatment means, annual hospitalization 4 to 5 times before the patient, every time 10 to 15 My god, have no within 18 months so far after herbal application.
Case 4
Chen, female, 52 years old, patient implanted a pacemaker more than 2 years because of heart disease, and body does not relax always, daily in Medicine, Western medicine are not interrupted, and afterwards using herbal application agent of the present invention 30 days, malaise symptoms are all eliminated, without the need for medication, heart during further consultation Dirty pacemaker already without will supplement can reach blood supply requirement.

Claims (7)

1. a kind of herbal application agent for treating coronary heart disease, it is characterised in that described herbal application agent is mainly matched somebody with somebody by following weight The Chinese medicine of ratio is made:210~230 parts of the root of kudzu vine, 180~200 parts of the red sage root, 130~150 parts of rhizoma alismatis, 140~160 parts of motherwort, 210~230 parts of ilex pubescens, 140~160 parts of pseudo-ginseng.90~110 parts of cassia twig, 130~150 parts of Rhizoma Sparganii, 130~150 parts of curcuma zedoary, 110~130 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 90~110 parts of rhizoma menispermi, 130~150 parts of hawthorn, 130~150 parts of tetrandra root, Ligusticum wallichii 130~150 Part, 90~110 parts of safflower, 90~110 parts of Chinese cassia tree.
2. it is according to claim 1 treatment coronary heart disease herbal application agent, it is characterised in that described herbal application agent by The Chinese medicine of following weight proportioning is made:220 parts of the root of kudzu vine, 100 parts of cassia twig, 130 parts of Rhizoma Sparganii, 130 parts of curcuma zedoary, 190 parts of the red sage root, pool Rush down 140 parts, 120 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 150 parts of motherwort, 220 parts of ilex pubescens, 100 parts of rhizoma menispermi, 140 parts of hawthorn, 140 parts of tetrandra root, 140 parts of Ligusticum wallichii, 100 parts of safflower, 90 parts of Chinese cassia tree, 150 parts of pseudo-ginseng.
3. it is according to claim 1 treatment coronary heart disease herbal application agent, it is characterised in that described herbal application agent by The Chinese medicine of following weight proportioning is made:230 parts of the root of kudzu vine, 90 parts of cassia twig, 150 parts of Rhizoma Sparganii, 130 parts of curcuma zedoary, 200 parts of the red sage root, pool Rush down 130 parts, 130 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 140 parts of motherwort, 230 parts of ilex pubescens, 90 parts of rhizoma menispermi, 150 parts of hawthorn, 130 parts of tetrandra root, river 150 parts of rhizome of chuanxiong, 90 parts of safflower, 110 parts of Chinese cassia tree, 140 parts of pseudo-ginseng.
4. it is according to claim 1 treatment coronary heart disease herbal application agent, it is characterised in that described herbal application agent by The Chinese medicine of following weight proportioning is made:210 parts of the root of kudzu vine, 110 parts of cassia twig, 130 parts of Rhizoma Sparganii, 150 parts of curcuma zedoary, 180 parts of the red sage root, pool Rush down 150 parts, 110 parts of FLOS CHRYSANTHEMI ALBA from Haizhou of China, 160 parts of motherwort, 210 parts of ilex pubescens, 110 parts of rhizoma menispermi, 130 parts of hawthorn, 150 parts of tetrandra root, 130 parts of Ligusticum wallichii, 110 parts of safflower, 90 parts of Chinese cassia tree, 160 parts of pseudo-ginseng.
5. a kind of preparation method of the herbal application agent of the treatment coronary heart disease according to any one of claim 2~4, its feature It is, by the root of kudzu vine, cassia twig, Rhizoma Sparganii, curcuma zedoary, the red sage root, rhizoma alismatis, FLOS CHRYSANTHEMI ALBA from Haizhou of China, motherwort, ilex pubescens, rhizoma menispermi, hawthorn, tetrandra root, river Rhizome of chuanxiong, safflower, Chinese cassia tree and pseudo-ginseng decontamination, traditional Chinese medicine powder of the mixed grinding into 150~200 mesh by weight ratio after drying sterilizing End, gained Chinese medicine powder add auxiliary material, and at 45~80 DEG C, heating stirring makes the herbal application agent.
6. it is according to claim 5 treatment coronary heart disease herbal application agent preparation method, it is characterised in that the auxiliary material It is made up of the Chinese medicine of following weight proportioning:600~620 parts of sesame oil, 440~460 parts of glycerine, 400~420 parts of vaseline, sheep 580~600 parts of fat of hair.
7. it is according to claim 6 treatment coronary heart disease herbal application agent preparation method, it is characterised in that the auxiliary material It is made up of the Chinese medicine of following weight proportioning:620 parts of sesame oil, 460 parts of glycerine, 420 parts of vaseline, 580 parts of lanolin.
CN201611258306.2A 2016-12-30 2016-12-30 Traditional Chinese medicine patch for treating coronary heart disease and preparation method thereof Pending CN106511911A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101850038A (en) * 2010-01-18 2010-10-06 郑延明 Transdermal medicament delivery patch preparation for treating coronary heart disease and method for preparing same
CN102139025A (en) * 2010-02-03 2011-08-03 北京阜康仁生物制药科技有限公司 Chinese medicinal preparation for treating coronary disease and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101850038A (en) * 2010-01-18 2010-10-06 郑延明 Transdermal medicament delivery patch preparation for treating coronary heart disease and method for preparing same
CN102139025A (en) * 2010-02-03 2011-08-03 北京阜康仁生物制药科技有限公司 Chinese medicinal preparation for treating coronary disease and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孙立滨: "中西医结合治疗冠心病50例疗效观察", 《中国当代医药》 *

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