CN106491854A - For treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof - Google Patents
For treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof Download PDFInfo
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- CN106491854A CN106491854A CN201611007795.4A CN201611007795A CN106491854A CN 106491854 A CN106491854 A CN 106491854A CN 201611007795 A CN201611007795 A CN 201611007795A CN 106491854 A CN106491854 A CN 106491854A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The present invention is disclosed for treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof, wherein, is counted by weight, mainly composed of the following components:25 35 parts of Herba Centellae;25 35 parts of Herba Hydrocotyleses;15 25 parts of Herba potentillae kleinianae Herba Potentillae Chinensis;5 15 parts of Herba Violae japonicae;5 15 parts of Hemerocallis citrina Baroni Herba Oxalidis Corniculatae;10 15 parts of glycerol;10 30 parts of starch;45 55 parts of distilled water;0.3 0.7 parts of sodium benzoate.Effect of the Chinese medicine composition be anti-inflammatory analgetic, dial the pus, eliminating stagnation, anti-virus sterilizing, infection, have prevention trauma infection contamination effect, without using any antibiotic.
Description
Technical field
The present invention relates to drug world, more particularly to a kind of Chinese medicine composition for treating skin and soft tissue infection and
Its preparation method.
Background technology
Skin and soft tissue infection, also known as skin and skin structure infection, is that pathogenic bacterium invade epidermis, corium and subcutaneous group
Knit the diseases associated with inflammation for causing.Skin and soft tissue infection is clinically commonly encountered diseases and frequently-occurring disease, with sending out for society and economy
Undesirable substance (such as pollutant, chemicals etc.) more and more, diabetes, the wound contacted in exhibition, people's daily life and work
Constantly rise etc. incidence rate, the sickness rate of such disease is also continuously increased, the only a few severe patient of the disease can concurrent deep group
Infection or pyemia is knitted, can threat to life.Major part show as gently-medium-sized, do not jeopardize patient's major organs and life, but with
Sample produces harmful effect to life, work.Wherein, neck, the infection of face can affect the image attractive in appearance of people, directly affect people's
Orthobiosiss and work, meanwhile, cause larger mental pressure.And surgical incision and drainage, antibiosis used in conventional Therapeutic Method
Extract for treating etc., surgical incision and drainage wound are big, easily produce larger cicatrix;The a large amount of frequent use of antibiotic, not only gives people
Liver, the vitals such as kidney cause larger infringement, while stronger dependency and drug resistance can be produced.Therefore, study
Invention one kind treats such disease, and reduces the natural drug of skin scar formation, be clinicing aspect in the urgent need to.
Content of the invention
In view of above-mentioned the deficiencies in the prior art, it is an object of the invention to provide a kind of be used for treating skin and soft tissue sense
Chinese medicine composition of dye and preparation method thereof, for the acute and chronic infectious diseases of skin soft tissue, such as folliculitises, furuncle, carbuncle, pouring
Hand shaft inflammation, acute cellulitis, Burn Infection, postoperative infection and decubital ulcer infection etc..
Technical scheme is as follows:
A kind of Chinese medicine composition for treating skin and soft tissue infection, wherein, is counted, by weight mainly by following
Group is grouped into:
The described Chinese medicine composition for treating skin and soft tissue infection, wherein, is counted by weight, also include with
The following group is grouped into;
Sodium benzoate 0.3-0.7 parts.
The described Chinese medicine composition for treating skin and soft tissue infection, wherein, is counted by weight, mainly by with
The following group is grouped into:
The described Chinese medicine composition for treating skin and soft tissue infection, wherein, is counted by weight, also include with
The following group is grouped into;
0.5 part of sodium benzoate.
The described Chinese medicine composition for treating skin and soft tissue infection, wherein, described for treating skin and soft
The Chinese medicine composition of tissue infection is paste.
A kind of preparation method of the Chinese medicine composition for being used for treating skin and soft tissue infection as above, wherein, bag
Include following steps:
Herba Centellae, Herba Hydrocotyleses, Herba potentillae kleinianae Herba Potentillae Chinensis, Herba Violae japonicae, Hemerocallis citrina Baroni Herba Oxalidis Corniculatae decocting are boiled 2-3 time, filtered while hot, are merged
Filtrate, is concentrated into 1: 4-5, obtains concentrated solution;
Concentrated solution is dried, is crushed, is sieved, obtain dry extract;
Glycerol is added in extract powder, is ground well, is added starch and stir evenly, obtain mixture;
Distilled water is boiled, sodium benzoate is added;
Distilled water is poured in mixture, is stirred continuously, water-bath is to gelatinizing;
Stir to cooling.
The described preparation method for treating the Chinese medicine composition of skin and soft tissue infection, wherein, the temperature of drying
For 60 DEG C;The size that sieves is 100 mesh.
Beneficial effect:The present invention is suitable for for treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof
In the acute and chronic infectious diseases of skin soft tissue, the such as skin such as folliculitises, furuncle, carbuncle, acute cellulitises, abscess, erysipelas
Local treatment;The malunited auxiliary treatment of postoperative wound.Effect of the Chinese medicine composition be antiinflammatory, pain relieving, dial the pus, eliminating stagnation,
Anti-virus sterilizing, have prevention trauma infection contamination effect, can replace topical antibiotic use.Herba Hydrocotyleses, Herba Centellae, Herba potentillae kleinianae Herba Potentillae Chinensis,
Herba Violae japonicae, Hemerocallis citrina Baroni Herba Oxalidis Corniculatae belong to Common Chinese Herbs, and edible is nontoxic.Remove during life-time service and slight prurituss occur individually
Uncomfortable outer, other untoward reaction are had no, safe.
Specific embodiment
Present invention offer is a kind of for treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof, for making this
The purpose of invention, technical scheme and effect are clearer, clear and definite, and the present invention is described in more detail below.It should be appreciated that this
The described specific embodiment in place is not intended to limit the present invention only in order to explain the present invention.
Chinese medicine composition for treating skin and soft tissue infection provided by the present invention, is counted, mainly by weight
Composed of the following components:
The Chinese medicine composition directed toward bacteria property skin and soft tissue infection, mainly takes heat clearing away, the antiinflammatory of Herba Hydrocotyleses, and accumulated snow
The eliminating inflammation and expelling toxin of grass, the pharmacological action for suppressing proliferation of fibrous tissue, coordinate Hemerocallis citrina Baroni Herba Oxalidis Corniculatae eliminating stasis to stop pain, the solution of Herba potentillae kleinianae Herba Potentillae Chinensis
Poison promoting blood circulation, effect of Herba Violae japonicae detumescence and drawing out poison, the four big symptoms for eliminating scytitiss are red, swollen, hot, bitterly, so as to reach treatment skin
The effect of skin furuncle carbuncle poison.
Wherein, Herba Hydrocotyleses have heat clearing away, detumescence, Detoxication, play main antiinflammatory action.Herba Centellae has heat-clearing and toxic substances removing,
Inducing diuresis and reducing edema effect.Proliferation of fibrous tissue can be suppressed and stimulate the replacement of deep skin cell.Play in said composition and promote
Wound healing, reduces cicatrization effect, and plays auxiliary antiinflammatory action.Hemerocallis citrina Baroni Herba Oxalidis Corniculatae has clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain
Effect, plays in the composition and reduces local pain effect.Herba potentillae kleinianae Herba Potentillae Chinensis have heat clearing away, removing toxic substances, promoting blood circulation effect, in the combination
Removing toxic substances promoting blood circulation effect is played in thing, is promoted inflammation to remove, is helped out.Herba Violae japonicae has heat-clearing and toxic substances removing, cool blood detumescence, external to have
The effect that antiinflammatory is drawn out pus by applying a plaster to the affected part, plays detumescence, the effect of evacuation of pus in the composition.Glycerol is substrate, belongs to secondary solvent.Starch is powder
Last composition, can absorb the purulent secretion that discharges, beneficial to medicine molding, convenient use.Distilled water be used for make powder starch into
Pasty state.Sodium benzoate is preservative, prevents mouldy and fermentation.
Herba Hydrocotyleses, Herba Centellae, Herba potentillae kleinianae Herba Potentillae Chinensis, Herba Violae japonicae, Hemerocallis citrina Baroni Herba Oxalidis Corniculatae belong to Common Chinese Herbs, and edible is nontoxic.
During life-time service in addition to there is individually slight prurituss discomfort, other untoward reaction are had no, safe.
Most preferred embodiment scheme is also provided in the present invention, the compositionss drug effect prepared using following proposal is optimal, tool
Count by weight, mainly by following components group in body ground, the Chinese medicine composition for treating skin and soft tissue infection
Into:
Provided by the present invention for treating the Chinese medicine composition of skin and soft tissue infection through clinical verification for many years,
Safe and reliable, determined curative effect, in combination with the Chinese drug preparation technique of modernization, has produced Chinese medicine easy to use, eutherapeutic
Paste, is applied directly to affected part.The preparation method of the Chinese medicine composition is also provided in the present invention, following step is specifically included
Suddenly:
Herba Hydrocotyleses, Herba Centellae, Herba potentillae kleinianae Herba Potentillae Chinensis, Herba Violae japonicae, Hemerocallis citrina Baroni Herba Oxalidis Corniculatae decocting are boiled 2-3 time, filtered while hot, are merged
Filtrate, is concentrated into 1: 4-5, obtains concentrated solution;
Concentrated solution is positioned over 60 DEG C of drying of baking box, is crushed, is crossed 100 mesh sieves, obtain dry extract;
Glycerol is added in extract powder, is ground well, is added starch and stir evenly, obtain mixture;
Distilled water is boiled, sodium benzoate is added;
Distilled water is poured in mixture, is stirred continuously, water-bath is to gelatinizing;
Stir to cooling.
Below by way of specific embodiment, the invention will be further described
Embodiment 1
Preparation technology:Herba Centellae, Herba Hydrocotyleses, Herba potentillae kleinianae Herba Potentillae Chinensis, Herba Violae japonicae, Hemerocallis citrina Baroni Herba Oxalidis Corniculatae decocting are boiled 2-3 time, while hot
Filter, merging filtrate is concentrated into 1: 4-5, obtain concentrated solution.Concentrated solution is put 60 DEG C of drying of baking box, is crushed, is crossed 100 mesh sieves, obtain
Dry extract.In extract powder, add glycerol 10ml to grind well, add 10-30 gram of starch and stir evenly, obtain mixture;By distilled water
50ml boils 0.5 gram of sodium benzoate of addition.The distilled water for being added with sodium benzoate is poured in mixture, is stirred continuously, water-bath
To gelatinizing.Finally stir to cooling, both obtained external application paste.
The Chinese medicine composition for treating skin carbuncle furuncle described in being made using this proportioning, used in clinic, external application,
Daily two~tri- times.External reaches red and swollen range shorter after 1-2 days, local skin tight feeling disappears, and pain relief, pus point go out
Existing, 3-5 days, red and swollen basic regression, puss were discharged, 7-10 days wound healings.Diabeticss concurrent lower limb infection etc. is such as treated
Chronic skin infectious disease needs the extended treatment time to be healed to wound completely, about needs 20-30 days.
Case 1:Xx, female, 10 years old, because " right lateral thigh lateral cutaneous pain 2 days " was examined in 201x July 10.Suffer from
Person goes to a doctor first 2 days and thigh lateral cutaneous pain occurs without obvious inducement, without heating, does not give treatment, pain to increase in progressive, then
To examine.Have a medical check-up:36.5 DEG C of body temperature, psychoreaction is good, and the heart, lung, abdomen are had a medical check-up without exception, and extremity acra is warm, capillary filling
2 seconds time.The red knot property enclosed mass of the visible 5*5cm sizes of the outer middle side part of right lateral thigh, with surrounding skin unclear, the no pus of boundary
Point, local Pi Wengao, skin tension are high, and pressing pain is obvious.Diagnosis:Skin furuncle and phyma.1 gained paste of embodiment is spread on trouble
Place, changes, pain relief in second day, local skin Wen Bugao sooner or later, and skin tension is alleviated;After treatment 3 days, see pus point, puncture
Pus point, the more pus and blood of outflow, continual cure, the 5th day, non-goodbye pus flowed out, without pain, the red range shorter of skin to 1*1cm
Size, is further continued for treating 2 days, heals completely, have no obvious cicatrix at present, has slight pigmentation, pigmentation area about 1*
1cm sizes.
Case 2:Multitude xx, man, 47 years old, because " wound protracted course of disease 20 days after the instep wound of right side " comes in 201x Augusts on the 2nd
Examine.Because surprisingly being damaged by irony agriculture device during farming before 20 days, there is the irregular wound of a 3cm length to patient assessment in right crus of diaphragm instep, from
Row gives and cleaning a wound, and does not go regular debridement and suturing and sterilizing bandaging is processed, and after 3 days, oozing out occurs in wound, transudate be septic,
To local clinic, local clinic gives Mupirocin Ointment to smear affected part, and hands over holding wound clean, it is to avoid touch water;Patient medication
Five days, period did not followed the doctor's advice, and continued to be engaged in farm work, and wound is without improvement, and has and increase trend, then examining.Have a medical check-up:Body weight 36.5
DEG C, psychoreaction is good, and the heart, lung, abdomen are had a medical check-up without exception.Instep visible 3*2cm sizes in right side are festered, and periphery skin is slightly red, office
Portion's skin temperature is slightly higher, the visible purulent secretion in injury.Diagnosis:Skin ulceration.1 gained paste of embodiment is spread on affected part, sooner or later more
Plastic sheeting parcel protection, other times is given to keep ventilation when changing, and handing over farming.After treatment 3 days, secretions are reduced, locally
Dry clean, wound circumference is not red, continuously uses paste 15 days, wound healing.Current patient's freedom of movement, partially visible cicatrix, scar
Trace area about 2*2cm sizes.
It should be appreciated that the application of the present invention is not limited to above-mentioned citing, and for those of ordinary skills, can
To be improved according to the above description or be converted, all these modifications and variations should all belong to the guarantor of claims of the present invention
Shield scope.
Claims (7)
1. a kind of Chinese medicine composition for treating skin and soft tissue infection, it is characterised in that count by weight, mainly by
Following components is constituted:
2. the Chinese medicine composition for treating skin and soft tissue infection according to claim 1, it is characterised in that by weight
Amount number meter, also includes that following components is constituted;
Sodium benzoate 0.3-0.7 parts.
3. the Chinese medicine composition for treating skin and soft tissue infection according to claim 1, it is characterised in that by weight
Amount number meter, mainly composed of the following components:
4. the Chinese medicine composition for treating skin and soft tissue infection according to claim 3, it is characterised in that by weight
Amount number meter, also includes that following components is constituted;
0.5 part of sodium benzoate.
5., according to the arbitrary described Chinese medicine composition for treating skin and soft tissue infection of Claims 1 to 4, its feature exists
In the Chinese medicine composition for treating skin and soft tissue infection is paste.
6. a kind of as claimed in claim 2 for treating the preparation method of the Chinese medicine composition of skin and soft tissue infection, its
It is characterised by, comprises the following steps:
Herba Centellae, Herba Hydrocotyleses, Herba potentillae kleinianae Herba Potentillae Chinensis, Herba Violae japonicae, Hemerocallis citrina Baroni Herba Oxalidis Corniculatae decocting are boiled 2-3 time, filtered while hot, merge filter
Liquid, is concentrated into 1: 4-5, obtains concentrated solution;
Concentrated solution is dried, is crushed, is sieved, obtain dry extract;
Glycerol is added in extract powder, is ground well, is added starch and stir evenly, obtain mixture;
Distilled water is boiled, sodium benzoate is added;
Distilled water is poured in mixture, is stirred continuously, water-bath is to gelatinizing;
Stir to cooling.
7. the preparation method for treating the Chinese medicine composition of skin and soft tissue infection according to claim 6, its are special
Levy and be, the temperature of drying is 60 DEG C;The size that sieves is 100 mesh.
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CN201611007795.4A CN106491854A (en) | 2016-11-16 | 2016-11-16 | For treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof |
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CN201611007795.4A CN106491854A (en) | 2016-11-16 | 2016-11-16 | For treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof |
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CN201611007795.4A Pending CN106491854A (en) | 2016-11-16 | 2016-11-16 | For treating Chinese medicine composition of skin and soft tissue infection and preparation method thereof |
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