CN106491814A - A kind of treat Traditional Chinese medicinal patch of gout and preparation method thereof - Google Patents
A kind of treat Traditional Chinese medicinal patch of gout and preparation method thereof Download PDFInfo
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- CN106491814A CN106491814A CN201611000066.6A CN201611000066A CN106491814A CN 106491814 A CN106491814 A CN 106491814A CN 201611000066 A CN201611000066 A CN 201611000066A CN 106491814 A CN106491814 A CN 106491814A
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The present invention relates to the field of Chinese medicines, and in particular to a kind of treat Traditional Chinese medicinal patch of gout and preparation method thereof, the Traditional Chinese medicinal patch of the treatment gout is made up of the bulk drug of following weight portion：24 28 parts of giant knotweed, 15 22 parts of prepared rhizome of rehmannia, 20 25 parts of honeysuckle, 10 15 parts of Polygonum multiflower knotweed, 18 25 parts of bark of ash, 12 18 parts of earthworm, 10 15 parts of corydalis tuber, 10 18 parts of Flos Albiziae, 8 12 parts of the root bark of tree peony, 6 14 parts of teasel root, 12 16 parts of Radix Glycyrrhizae, 16 20 parts of Ligusticum wallichii, 18 22 parts of pseudo-ginseng, 12 15 parts of the Radix Astragali, 8 12 parts of the banksia rose, its preparation method includes drying and crushes, extract, concentrate and dry, four big step of preparation, the present invention has swelling and pain relieving, dredging collateral wind-dispelling, promoting blood circulation and removing blood stasis, the effects such as anti-inflammatory, there is significant curative effect to treating gout, and it is easy to use, have no toxic side effect, non-stimulated to skin, preparation method is simply efficient, achievable industrialized production.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of treat Traditional Chinese medicinal patch of gout and preparation method thereof.
Background technology
Gout be by monosodium urate salt (MSU) deposit caused by crystal correlation arthropathy, with purine metabolic disturbance and
(or) hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis and chronic gout stone disease
Disease, mainly includes acute attack arthritis, tophus formation, tophaceous chornic arthritis, urate nephropathy and uric acid
Lithangiuria, severe one may occur in which joint deformity and renal insufficiency.Gout is often with Central obesity, hyperlipidemia, hypertension, 2 types
Diabetes and cardiovascular disease etc. are showed.Gout is more common in middle-aged male, and women only accounts for 5%, mainly postmenopausal women, and gout is sent out
There is rejuvenation trend.The natural history of gout can be divided into the fourth phase, i.e., the asymptomatic hyperuricemia phase, acute stage, the intermittent phase, slow
The property phase.
The forced-ventilated acid medicine and anti-inflammatory analgesic class medicine of antipodagric medicine, doctor trained in Western medicine in terms of multiplex colchicin etc are cured at present
Thing, though effective in cure side effect is also very serious.And modern doctor has extensively carried out the clinic of traditional Chinese medicine prevention gout and experiment is ground
Study carefully, make great progress, it is shown that there is to gout traditional Chinese medicine anti-inflammatory, analgesia, anti-trioxypurine, preventing and treating recurrence etc. preferably to face
Bed curative effect, and toxic and side effect is little, therefore have good application and DEVELOPMENT PROSPECT.But the soup type prescription of traditional Chinese medicine, need because people, because
When, prescription is constantly adjusted according to the course of disease, also limited by doctor's level and quality of medicinal material, lacked universality and convenience.
Content of the invention
The invention provides a kind of treat Traditional Chinese medicinal patch of gout and preparation method thereof, the Traditional Chinese medicinal patch of the treatment gout
Easy to use and have no toxic side effect, evident in efficacy to treating gout.
For realizing that object above, the present invention are achieved by the following technical programs：
A kind of Traditional Chinese medicinal patch for treating gout, is made up of the bulk drug of following weight portion：Giant knotweed 24-28 parts, prepared rhizome of rehmannia 15-
22 parts, honeysuckle 20-25 parts, Polygonum multiflower knotweed 10-15 parts, bark of ash 18-25 parts, earthworm 12-18 parts, corydalis tuber 10-15 parts, Flos Albiziae
10-18 parts, root bark of tree peony 8-12 parts, teasel root 6-14 parts, Radix Glycyrrhizae 12-16 parts, Ligusticum wallichii 16-20 parts, pseudo-ginseng 18-22 parts, Radix Astragali 12-15
Part, banksia rose 8-12 parts.
Preferably, the Traditional Chinese medicinal patch of the treatment gout is made up of the bulk drug of following weight portion：26 parts of giant knotweed, prepared rhizome of rehmannia
18 parts, 22 parts of honeysuckle, 13 parts of Polygonum multiflower knotweed, 22 parts of bark of ash, 15 parts of earthworm, 12 parts of corydalis tuber, 14 parts of Flos Albiziae, 10 parts of the root bark of tree peony, continuous
Disconnected 8 parts, 14 parts of Radix Glycyrrhizae, 18 parts of Ligusticum wallichii, 20 parts of pseudo-ginseng, 13 parts of the Radix Astragali, 10 parts of the banksia rose.
The preparation method of the Traditional Chinese medicinal patch for the treatment of gout, comprises the following steps：
(1) dry and crush：Each bulk drug is dried 2-4h at 60-70 DEG C respectively, is crushed afterwards, cross 30-50 mesh sieves,
Obtain each bulk drug meal；
(2) extract：Weigh each bulk drug meal in proportion, each bulk drug meal is sufficiently mixed, compound is obtained；To mixing
Add the 12-14 times of 40-60% ethanol immersion 30-40min for measuring in material, 30-40min is extracted with ultrasonic extractor, filter, must filter
Liquid one, residue add the 8-10 times of 40-60% ethanol ultrasonic extractor that measures to extract 20-25min, filter, obtain filtrate two, merge
Filtrate one and filtrate two, obtain extract；
(3) concentrate and dry：Extract is carried out reduced pressure concentration, concentrate drying, crush, sieve to obtain herb powder；
(4) preparation：Herb powder addition auxiliary material is mixed thoroughly, is spread out in patch and is cut into small pieces, obtain final product the Chinese medicine for the treatment of gout
Drug paste.
Preferably, it is 40 mesh to cross grit number in step (1).
Preferably, the 50% ethanol immersion 35min of 13 times of amounts are added in step (2) in compound.
Preferably, in step (3), drying means is spray drying.
Preferably, it is 120-160 mesh to cross grit number in step (3).
In the present invention, effect of each important source material medicinal material is as follows：
Giant knotweed：Slight bitter, it is slightly cold, Return liver, courage, lung channel.Removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, blood stasis removing analgesic is relieving cough and reducing sputum, is used for
Treatment arthralgia due to wind-dampness, carbuncle sore tumefacting virus, scald, instep beat the diseases such as damage, cough with lung heat.
Prepared rhizome of rehmannia：Sweet, tepor, the thoughts of returning home, liver and kidney channel.Nourishing yin and supplementing blood, beneficial essence fill out marrow, for the deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees,
The diseases such as osteopyrexia and fever, blood deficiency chlorosis, palpitation and severe palpitation.
Honeysuckle：Sweet, cold, return lung, the heart, stomach.There is clearing heat and detoxicating, anti-inflammatory, qi-restoratives to treat wind, cure mainly warm disease and send out
The diseases such as heat, heat toxin large carbuncle.
Polygonum multiflower knotweed：Sweet, slight bitter, flat, nourishing heart, the thoughts of returning home, spleen, kidney, Liver Channel are calmed the nerves, dredging collateral, wind-dispelling.
Bark of ash：Pungent, bitter, put down.Return stomach, liver, gallbladder channel.Wines used as antirheumatic, clearing away damp-heat, stopping numbness pain.For muscle arteries and veins contraction, joint acid
Bitterly, the diseases such as afternoon tidal fever, infantile malnutrition generates heat.
Earthworm：Cold, salty, Return liver, stomach, lung, bladder warp.The effects such as there is heat-clearing, flat liver, Zhichuan, dredging collateral, cures mainly hyperpyrexia and is tired of
Hot-tempered, twitch, dyspnea and cough due to lung-heat, numbness pain limb fiber crops etc. are demonstrate,proved.
Corydalis tuber：Temperature, pungent, bitter, the thoughts of returning home, spleen, liver, lung have promoting blood circulation to remove blood stasis, the effect of regulating qi-flowing for relieving pain to cure mainly stomachache, bruise and damage
Wound etc..
Flos Albiziae：Sweet, flat, the thoughts of returning home, spleen etc. are passed through, Shu Yu, qi-regulating, calm the nerves, active, blood-nourishing, enriching yin kidney, clear away heart-fire improving eyesight.
The root bark of tree peony：Bitter, pungent, be slightly cold, the thoughts of returning home, liver and kidney channel.Clearing heat and cooling blood, promoting blood circulation to remove blood stasis cure mainly the pain of injury caused by falling and tumbling, beriberoid pyretic arthralgia
Deng disease.
Teasel root：Tepor, hardship, pungent, return liver and kidney channel.The effects such as having filling liver kidney, strengthening the bones and muscles, continuous injured, cure mainly kidney deficiency and liver,
The diseases such as soreness and weakness of waist and knees, arthralgia due to wind-dampness, injury of tendon and muscle fracture.
Radix Glycyrrhizae：Sweet, flat, returns spleen, stomach, lung channel.There is nourishing the stomach, enrich blood, invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, rush down
The effects such as fire, removing toxic substances, coordinating the drug actions of a prescription.
Ligusticum wallichii：Pungent, temperature, Return liver, gallbladder channel.Former times people meaning Ligusticum wallichii is the gas medicine in blood, nearly say its reside pungent dissipate, Xie Yu, sensible, only
The functions such as pain.
Pseudo-ginseng：Temperature, sweet, slight bitter, Return liver, stomach, large intestine channel.There is hemostasis, promoting blood circulation and removing blood stasis, detumescence ding-tong, strengthening by means of tonics, resist
The effects such as fatigue, raising body's immunity.
The Radix Astragali：Sweet, tepor, return lung, spleen, liver and kidney channel.The Radix Astragali have enhancing body's immunity, liver protection, diuresis, anti-aging,
Resisting stress, step-down and wide antibacterial action.Radix Astragali energy coronary artery dilator, improves myocardial blood supply, improves immunologic function.
The banksia rose：Pungent, bitter, temperature, returns spleen, large intestine, tri-jiao channel.Promoting the circulation of qi, pain relieving, invigorating the spleen help digestion, and cure mainly abdominal distention, tell
Have loose bowels, weight after dysentery, it may also be used for the disease such as chest gastral cavity distending pain, weight after rush down dysentery, dyspepsia, do not feel like eating.
Beneficial effects of the present invention are：
1. the effects such as present invention has swelling and pain relieving, dredging collateral wind-dispelling, promoting blood circulation and removing blood stasis, anti-inflammatory, to treating arthralgia due to wind-dampness, tendon and vessel
The diseases such as contraction, soreness and weakness of waist and knees have good curative effect, while internal uric acid can be reduced, make human body recover original autonomous acid discharge work(
Can, metabolic mechanism is rebuild, fundamentally cures gout.The Traditional Chinese medicinal patch of present invention treatment gout can avoid oral drugs to digestion
The damage of system and the impact to hepatic and renal function.The present invention is easy to use, has no toxic side effect, non-stimulated to skin.
2. preparation method of the present invention adopts ultrasonic wave extraction, and extraction efficiency is high, is conducive to the precipitation of active ingredient, it is to avoid
Because the heat time is long, the fearness of the material strong to thermal sensitivity in medicinal material is destroyed.It is that gained traditional Chinese medicine powder quality is good using spray drying,
There is good dispersiveness, mobility, the preparation method is simply efficient, and preparation process parameter is easy to control, can achieve industry metaplasia
Produce.
Specific embodiment
With reference to the technical solution that specific embodiment further illustrates the present invention, embodiment is not to be construed as right
The restriction of technical solution.
Embodiment 1：
A kind of Traditional Chinese medicinal patch for treating gout, is made up of the bulk drug of following weight portion：26 parts of giant knotweed, 18 parts of prepared rhizome of rehmannia,
22 parts of honeysuckle, 13 parts of Polygonum multiflower knotweed, 22 parts of bark of ash, 15 parts of earthworm, 12 parts of corydalis tuber, 14 parts of Flos Albiziae, 10 parts of the root bark of tree peony, 8 parts of teasel root,
14 parts of Radix Glycyrrhizae, 18 parts of Ligusticum wallichii, 20 parts of pseudo-ginseng, 13 parts of the Radix Astragali, 10 parts of the banksia rose.
The preparation method of the Traditional Chinese medicinal patch for the treatment of gout, comprises the following steps：
(1) dry and crush：Each bulk drug is dried 2h at 70 DEG C respectively, is crushed afterwards, crossed 40 mesh sieves, obtain each raw material
Medicine meal；
(2) extract：Weigh each bulk drug meal in proportion, each bulk drug meal is sufficiently mixed, compound is obtained；To mixing
Adding the 50% ethanol immersion 35min of 13 times of amounts in material, 35min being extracted with ultrasonic extractor, filter, obtain filtrate one, residue adds 9
50% ethanol of amount extracts 25min with ultrasonic extractor again, filters, obtains filtrate two, merging filtrate one and filtrate two, must extract
Liquid；
(3) concentrate and dry：Extract is carried out reduced pressure concentration, concentrate is spray-dried, crush, cross 160 mesh sieves obtains
Herb powder；
(4) preparation：Herb powder addition auxiliary material is mixed thoroughly, is spread out in patch and is cut into small pieces, obtain final product the Chinese medicine for the treatment of gout
Drug paste.
Embodiment 2：
A kind of Traditional Chinese medicinal patch for treating gout, is made up of the bulk drug of following weight portion：28 parts of giant knotweed, 15 parts of prepared rhizome of rehmannia,
25 parts of honeysuckle, 10 parts of Polygonum multiflower knotweed, 25 parts of bark of ash, 12 parts of earthworm, 15 parts of corydalis tuber, 10 parts of Flos Albiziae, 12 parts of the root bark of tree peony, 6 parts of teasel root,
16 parts of Radix Glycyrrhizae, 16 parts of Ligusticum wallichii, 22 parts of pseudo-ginseng, 12 parts of the Radix Astragali, 12 parts of the banksia rose.
The preparation method of the Traditional Chinese medicinal patch for the treatment of gout, comprises the following steps：
(1) dry and crush：Each bulk drug is dried 4h at 60 DEG C respectively, is crushed afterwards, cross 350 mesh sieves, get Ge Yuan
Material medicine meal；
(2) extract：Weigh each bulk drug meal in proportion, each bulk drug meal is sufficiently mixed, compound is obtained；To mixing
Adding the 40% ethanol immersion 40min of 14 times of amounts in material, 30min being extracted with ultrasonic extractor, filter, obtain filtrate one, residue adds
40% ethanol of 10 times of amounts extracts 20min with ultrasonic extractor, filters, obtains filtrate two, merging filtrate one and filtrate two, must carry
Take liquid；
(3) concentrate and dry：Extract is carried out reduced pressure concentration, concentrate is spray-dried, crush, cross 120 mesh sieves obtains
Herb powder；
(4) preparation：Herb powder addition auxiliary material is mixed thoroughly, is spread out in patch and is cut into small pieces, obtain final product the Chinese medicine for the treatment of gout
Drug paste.
Embodiment 3：
A kind of Traditional Chinese medicinal patch for treating gout, is made up of the bulk drug of following weight portion：24 parts of giant knotweed, 22 parts of prepared rhizome of rehmannia,
20 parts of honeysuckle, 15 parts of Polygonum multiflower knotweed, 18 parts of bark of ash, 18 parts of earthworm, 10 parts of corydalis tuber, 18 parts of Flos Albiziae, 8 parts of the root bark of tree peony, 14 parts of teasel root,
12 parts of Radix Glycyrrhizae, 20 parts of Ligusticum wallichii, 18 parts of pseudo-ginseng, 15 parts of the Radix Astragali, 8 parts of the banksia rose.
The preparation method of the Traditional Chinese medicinal patch for the treatment of gout, comprises the following steps：
(1) dry and crush：Each bulk drug is dried 3h at 65 DEG C respectively, is crushed afterwards, crossed 30 mesh sieves, obtain each raw material
Medicine meal；
(2) extract：Weigh each bulk drug meal in proportion, each bulk drug meal is sufficiently mixed, compound is obtained；To mixing
Adding the 60% ethanol immersion 30min of 12 times of amounts in material, 40min being extracted with ultrasonic extractor, filter, obtain filtrate one, residue adds 8
60% ethanol of amount extracts 25min with ultrasonic extractor again, filters, obtains filtrate two, merging filtrate one and filtrate two, must extract
Liquid；
(3) concentrate and dry：Extract is carried out reduced pressure concentration, concentrate is spray-dried, crush, cross 140 mesh sieves obtains
Herb powder；
(4) preparation：Herb powder addition auxiliary material is mixed thoroughly, is spread out in patch and is cut into small pieces, obtain final product the Chinese medicine for the treatment of gout
Drug paste.
Embodiment 4：
A kind of Traditional Chinese medicinal patch for treating gout, is made up of the bulk drug of following weight portion：28 parts of giant knotweed, 22 parts of prepared rhizome of rehmannia,
20 parts of honeysuckle, 10 parts of Polygonum multiflower knotweed, 25 parts of bark of ash, 18 parts of earthworm, 10 parts of corydalis tuber, 18 parts of Flos Albiziae, 8 parts of the root bark of tree peony, 6 parts of teasel root,
16 parts of Radix Glycyrrhizae, 20 parts of Ligusticum wallichii, 18 parts of pseudo-ginseng, 12 parts of the Radix Astragali, 12 parts of the banksia rose.
The preparation method of the Traditional Chinese medicinal patch for the treatment of gout, comprises the following steps：
(1) dry and crush：Each bulk drug is dried 4h at 70 DEG C respectively, is crushed afterwards, crossed 50 mesh sieves, obtain each raw material
Medicine meal；
(2) extract：Weigh each bulk drug meal in proportion, each bulk drug meal is sufficiently mixed, compound is obtained；To mixing
Adding the 40% ethanol immersion 40min of 12 times of amounts in material, 30min being extracted with ultrasonic extractor, filter, obtain filtrate one, residue adds 8
40% ethanol of amount extracts 20min with ultrasonic extractor again, filters, obtains filtrate two, merging filtrate one and filtrate two, must extract
Liquid；
(3) concentrate and dry：Extract is carried out reduced pressure concentration, concentrate is spray-dried, crush, cross 160 mesh sieves obtains
Herb powder；
(4) preparation：Herb powder addition auxiliary material is mixed thoroughly, is spread out in patch and is cut into small pieces, obtain final product the Chinese medicine for the treatment of gout
Drug paste.
Embodiment 5：
A kind of Traditional Chinese medicinal patch for treating gout, is made up of the bulk drug of following weight portion：25 parts of giant knotweed, 20 parts of prepared rhizome of rehmannia,
23 parts of honeysuckle, 12 parts of Polygonum multiflower knotweed, 20 parts of bark of ash, 14 parts of earthworm, 15 parts of corydalis tuber, 12 parts of Flos Albiziae, 9 parts of the root bark of tree peony, 12 parts of teasel root,
12 parts of Radix Glycyrrhizae, 16 parts of Ligusticum wallichii, 22 parts of pseudo-ginseng, 12 parts of the Radix Astragali, 9 parts of the banksia rose.
The preparation method of the Traditional Chinese medicinal patch for the treatment of gout is with embodiment 1.
Embodiment 6：
A kind of Traditional Chinese medicinal patch for treating gout, is made up of the bulk drug of following weight portion：24 parts of giant knotweed, 15 parts of prepared rhizome of rehmannia,
25 parts of honeysuckle, 15 parts of Polygonum multiflower knotweed, 18 parts of bark of ash, 12 parts of earthworm, 15 parts of corydalis tuber, 10 parts of Flos Albiziae, 12 parts of the root bark of tree peony, 8 parts of teasel root,
14 parts of Radix Glycyrrhizae, 18 parts of Ligusticum wallichii, 20 parts of pseudo-ginseng, 15 parts of the Radix Astragali, 8 parts of the banksia rose.
The preparation method of the Traditional Chinese medicinal patch for the treatment of gout is with embodiment 2.
Clinical efficacy is summarized：
1. general data：The Traditional Chinese medicinal patch of this treatment gout is used for treating patient with gout 80, wherein man 55, and female 25
Example, age 35-70 year, the course of disease-five years a year.
2. usage and dosage：Traditional Chinese medicinal patch daily one prepared by embodiment 1 is affixed on affected part, is within one week a course for the treatment of, root
According to the state of an illness continuously using the 3-4 courses for the treatment of.
3. diagnosis basis：
(1) how with single toe joint, the tcm diagnosis specification of gout.The right congestion and swelling pain of soldier, gradually pain is acute stings such as tiger, and daytime is light
Night very, recurrent exerbation, can occur together heat, headache etc. disease.
(2) aging male is more common in, there can be gout family history.Often because tired, eat and drink immoderately, eat containing high purine diet,
The induction such as drink and catch cold.
(3) from the beginning of can simple joint morbidity, with the first toe joint as common.After then ankle, with, finger and other Minor articulus,
Occur red, swollen, hot, bitterly, very then articular cavity can have sepage.After recurrent exerbation, can with periarticular and auricle helix and toe, refer to
Occurs " block " tophus between bone.
(4) blood uric acid, urine uric acid increase.Stage of attack total white blood cells can be raised.
(5) make the inspection such as the scanning of kidney B ultrasonic, routine urinalysis, renal function if necessary, to understand nephropathy situation after gout.X-ray is taken the photograph
Piece inspection can show that the sclerotin of cartilage edge adjacent joints has irregular sample round defect of giving a farfetched interpretation.
4. criterion of therapeutical effect：
(1) cure：Symptom disappears, and laboratory examination is normal.
(2) take a turn for the better：Arthroncus is disappeared, and pain relief, laboratory examination make moderate progress.
(3) invalid：Symptom laboratory examination is unchanged.
5. therapeutic effect：In the clinical observation case, 3-4 course for the treatment of of medicine is pasted, cure 22, taken a turn for the better 52, invalid 6,
Total effective rate is 92.5%, and toxic and side effect does not occur during treatment.It can thus be appreciated that Traditional Chinese medicinal patch obtained in the present invention can be safe
Gout is effectively treated.
6. model case：
Case 1：Lee, man 55 years old, suffer from gout and have 2 years, leg painful swelling of joints, hurt like hell.Take western medicine,
But curative effect is unstable, can usually recur.Good using Traditional Chinese medicinal patch 1 course for the treatment of posterior joint swelling prepared by the embodiment of the present invention 1
Turn, pain relief, after being continuing with 1 course for the treatment of of Traditional Chinese medicinal patch of the present invention, arthroncus disappears, and without pain is continuing with this
1 course for the treatment of of bright Traditional Chinese medicinal patch consolidates curative effect, has fully recovered, and does not recur within nearly 2 years.
Case 2：Chen, man 64 years old, suffer from gout and have 4 years, and leg painful swelling of joints is serious, frequently shows effect.It is continuing with this
After 2 courses for the treatment of of invention Traditional Chinese medicinal patch, arthroncus disappears, pain relief, is continuing with 2 courses for the treatment of of Traditional Chinese medicinal patch of the present invention and consolidates
Curative effect, has fully recovered, and does not recur within nearly 2 years.
Claims (7)
1. a kind of Traditional Chinese medicinal patch for treating gout, it is characterised in that be made up of the bulk drug of following weight portion：Giant knotweed 24-28 parts,
Prepared rhizome of rehmannia 15-22 parts, honeysuckle 20-25 parts, Polygonum multiflower knotweed 10-15 parts, bark of ash 18-25 parts, earthworm 12-18 parts, corydalis tuber 10-15
Part, Flos Albiziae 10-18 parts, root bark of tree peony 8-12 parts, teasel root 6-14 parts, Radix Glycyrrhizae 12-16 parts, Ligusticum wallichii 16-20 parts, pseudo-ginseng 18-22 parts, Huang
Stilbene 12-15 parts, banksia rose 8-12 parts.
2. according to claim 1 treatment gout Traditional Chinese medicinal patch, it is characterised in that by the bulk drug system of following weight portion
Into：26 parts of giant knotweed, 18 parts of prepared rhizome of rehmannia, 22 parts of honeysuckle, 13 parts of Polygonum multiflower knotweed, 22 parts of bark of ash, 15 parts of earthworm, 12 parts of corydalis tuber, silk tree
Spend 14 parts, 10 parts of the root bark of tree peony, 8 parts of teasel root, 14 parts of Radix Glycyrrhizae, 18 parts of Ligusticum wallichii, 20 parts of pseudo-ginseng, 13 parts of the Radix Astragali, 10 parts of the banksia rose.
3. the preparation method of the Traditional Chinese medicinal patch of the treatment gout according to any one of claim 1-2, it is characterised in that include
Following steps：
(1) dry and crush：Each bulk drug is dried 2-4h at 60-70 DEG C respectively, is crushed afterwards, crossed 30-50 mesh sieves, obtain respectively
Bulk drug meal；
(2) extract：Weigh each bulk drug meal in proportion, each bulk drug meal is sufficiently mixed, compound is obtained；To in compound
Plus the 12-14 times of 40-60% ethanol immersion 30-40min for measuring, 30-40min is extracted with ultrasonic extractor, filter, obtain filtrate
One, residue adds the 8-10 times of 40-60% ethanol ultrasonic extractor that measures to extract 20-25min, filters, obtains filtrate two, merges filter
Liquid one and filtrate two, obtain extract；
(3) concentrate and dry：Extract is carried out reduced pressure concentration, concentrate drying, crush, sieve to obtain herb powder；
(4) preparation：Herb powder addition auxiliary material is mixed thoroughly, is spread out in patch and is cut into small pieces, obtain final product the Traditional Chinese medicinal patch for the treatment of gout.
4. according to claim 3 treatment gout Traditional Chinese medicinal patch preparation method, it is characterised in that step (1)
Middle grit number of crossing is 40 mesh.
5. according to claim 3 treatment gout Traditional Chinese medicinal patch preparation method, it is characterised in that step (2)
The middle 50% ethanol immersion 35min for adding 13 times of amounts in compound.
6. according to claim 3 treatment gout Traditional Chinese medicinal patch preparation method, it is characterised in that step (3)
Middle drying means is spray drying.
7. according to claim 3 treatment gout Traditional Chinese medicinal patch preparation method, it is characterised in that step (3)
Middle grit number of crossing is 120-160 mesh.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN116327826A (en) * | 2023-04-25 | 2023-06-27 | 国药集团健康产业研究院有限公司 | A Chinese medicinal composition with antiinflammatory, analgesic or uric acid reducing effects and its preparation |
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| CN102793878A (en) * | 2012-09-03 | 2012-11-28 | 吴鎏桢 | Gout fast analgesic paste |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793878A (en) * | 2012-09-03 | 2012-11-28 | 吴鎏桢 | Gout fast analgesic paste |
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| 唐丽等: "中医药治疗慢性痛风性关节炎临床观察", 《世界中西医结合杂志》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN116327826A (en) * | 2023-04-25 | 2023-06-27 | 国药集团健康产业研究院有限公司 | A Chinese medicinal composition with antiinflammatory, analgesic or uric acid reducing effects and its preparation |
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