CN106490345A - A kind of acidulant preparation method and its prepared acidulant - Google Patents
A kind of acidulant preparation method and its prepared acidulant Download PDFInfo
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- CN106490345A CN106490345A CN201610830843.3A CN201610830843A CN106490345A CN 106490345 A CN106490345 A CN 106490345A CN 201610830843 A CN201610830843 A CN 201610830843A CN 106490345 A CN106490345 A CN 106490345A
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- acid
- acidulant
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Abstract
The invention provides a kind of acidulant preparation method, first adsorb short-chain fatty acid with carrier one and lactic acid forms core A, lipid envelope material spraying forms microcapsule acid B in core A, adsorb phosphoric acid and/or lactic acid with carrier two again, powdery acid C is mixed to get with solid organic acid, then spherical pellet D is formed with powdery acid C parcel microcapsule acid B, finally in spherical pellet D surface spraying lipid envelope materials, obtain final product final acidulant product.The method can make acidulant realize that site-directed quantitative discharges, and outermost lipid envelope material enters the rapid corrosion of meeting and disintegrate after digestive tract, and then discharges substantial amounts of phosphoric acid and solid organic acid, so as to reduce rapidly gastric pH；And the lipid envelope material layer outside the inner core based on short-chain fatty acid is thicker, intestinal can be entered by stomach, slowly release short-chain fatty acid therein in intestinal, suppress harmful intestinal tract microorganism, regulating intestinal canal microecological balance.
Description
Technical field
The invention belongs to feed additive preparing technical field, and in particular to a kind of acidulant preparation method and its prepared
Acidulant.
Background technology
Acidulant has become the important feed additive after antibiotic with probiotics, enzyme preparation etc. with par
One of, lot of experiments research shows that acidulant is applied in animal productiong, can substitute part antibiotic agents, and this point is
Have been widely recognized.Acidulant topmost effect in animal cultivation has two aspects, and one is to reduce feedstuff and animal
Digestive tract pH value, provides most suitable digestive tract environment for animal, so as to improve digestive enzyme activity, and promotes animal to feed nutrients
The digestion and utilization of matter；Two is that acidulant can pass through to reduce gastrointestinal tract pH value and then suppress harmful microorganism breeding, promotes to have
Beneficial bacteria is bred, and so as to play regulating intestinal canal microecological balance, reduces the diarrhoea of animal and the generation of other diseases.
Acidulant is typically by the one kind in several acid such as phosphoric acid, lactic acid, citric acid, fumaric acid, formic acid, acetic acid and propanoic acid
Or several compositions, and substantial amounts of research shows that the acid stronger acid such as phosphoric acid, citric acid, fumaric acid disappears to reducing feedstuff and animal
Change road pH more favourable, and the short-chain fatty acid such as lactic acid and formic acid, acetic acid, propanoic acid has more preferable anti-microbial property, to animal intestinal
More beneficial.Or and acidulant common at present is directly to be simply mixed and be re-dubbed product various acid and carrier, or being
Product is formed by peplos are unified again after various acid mixing.There is certain defect in the product that both processing modes are obtained, right
In the product that former directly mixes compounding, which does not have sustained release performance, can discharge rapidly in gastric, under causing gastric pH drastically
Drop, and then suppress the gastric acid secretion of animal itself, and also too low pH is also possible to injure the tissue such as gastric mucosa；For latter is mixed
The product of peplos after conjunction, then there may be contrary problem, due to adopting lipid envelope mostly, in order which has preferably
Slow release effect, required membrane material are thicker, which may be caused to discharge comparatively large number of acid after entering animal gastric so that animal
Gastric pH cannot comparatively fast reach suitable scope, and then affect the activation of pepsinogen.
Therefore, study a kind of both can go out substantial amounts of acid in gastric quick release and its pH is declined rapidly, and can be suitable
Profit enters intestinal sustained release organic acid and causes intestinal microbial population to be able to the acidulant for adjusting, for the development of acidulant,
Tool is of great significance.
Content of the invention
It is an object of the invention to provide a kind of both can go out substantial amounts of acid in gastric quick release, can guarantee that again and hold in intestinal
The acidulant preparation method of continuous release organic acid,
The technical scheme is that there is provided a kind of acidulant preparation method, comprise the steps：
1) short-chain fatty acid and lactic acid are mixed, then is adsorbed with carrier one, formed core A.
2) core A is placed in side spray fluid bed, by lipid envelope material heating and melting, is sprayed at core A while hot
Form microcapsule acid B.
3) phosphoric acid and/or lactic acid carrier two are adsorbed, while solid organic acid is crushed, then the two mix homogeneously is obtained
Arrive powdery acid C.
4) microcapsule acid B is placed in dusting pellet processing machine, is added thereto to powdery acid C, while spraying into binding agent, make powdery acid
C is progressively enriched with the surface for being wrapped in microcapsule acid B, until final form spherical pellet D completely.
5) the lipid envelope material for melting is sprayed into spherical pellet D, obtains final product final acidulant product.
Further, above-mentioned short-chain fatty acid be formic acid, acetic acid, one or more in propanoic acid；The short-chain fatty acid
Mass fraction is 5～15 parts, and lactic acid mass fraction is 0～10 part, and one mass fraction of carrier is 10～20 parts.
Further, silicon dioxide of the above-mentioned carrier one for 80～120 mesh of particle diameter, carrier two are below 120 mesh of particle diameter
Silicon dioxide.
Further, above-mentioned lipid envelope material includes the one kind or several in stearic acid, stearic acid monoglycerides, palm stearin
Kind.
Further, above-mentioned microcapsule acid B is than core A weightenings 40～80%.
Further, above-mentioned steps 5) in lipid envelope material quality for spherical pellet D mass 5～15%.
Further, above-mentioned steps 3) in solid organic acid be citric acid and/or fumaric acid, and solid organic acid is crushed to
Below 120 mesh；The phosphoric acid quality number is 0～25 part, and lactic acid mass fraction is 0～30 part, solid organic acid mass fraction
For 5～20 parts.
Further, above-mentioned steps 4) in the mass ratio of powdery acid C and microcapsule acid B be 1:1～1.5.
Further, above-mentioned steps 4) in binding agent be dextrin, methylcellulose, the one kind or several in carboxy-propyl cellulose
The aqueous solution that plants；The consumption of binding agent for the quality of powdery acid C 5～10%.
In addition, the present invention also protects acidulant prepared by any of the above-described method.
Beneficial effects of the present invention：
(1) this acidulant preparation method that the present invention is provided allows the acidulant to realize that site-directed quantitative discharges, outermost layer
Lipid envelope material due to amount of coating material few, clothing film is relatively thin, enter after the digestive tract of animal can rapid corrosion and disintegrate, and then
Substantial amounts of phosphoric acid and solid organic acid is discharged, so as to reduce rapidly gastric pH；And the inner core based on short-chain fatty acid due to
Amount of coating material is more, and lipid envelope material layer is thicker, so intestinal can be entered by stomach, the Digestive Enzyme and aqueouss in intestinal
Further corrosion and disintegrate under environment, so as to slowly release short-chain fatty acid therein, suppress harmful intestinal tract microorganism, adjust
Intestinal microecology is balanced.
(2) the acidulant fat a small amount of as outermost layer has been coated obtained in this acidulant preparation method that the present invention is provided
Matter coated fertilizer so which stably can preserve, and do not react with the other compositions in feedstuff, it is to avoid cause in feedstuff
The loss of nutritional labeling.
Specific embodiment
Below to the embodiment of the present invention in technical scheme be clearly and completely described, it is clear that described embodiment
Only a part of embodiment of the invention, rather than whole embodiments.Embodiment in based on the present invention, the common skill in this area
All other embodiment that art personnel are obtained under the premise of creative work is not made, belongs to the model of present invention protection
Enclose.
Embodiment 1：
A kind of preparation method of acidulant is present embodiments provided, following steps are specifically included：
(1) 2 parts of formic acid, 5 parts of acetic acid, 8 parts of propanoic acid are mixed, is sprayed into
Mixing and absorption, obtains core A.
(2) above-mentioned core A is placed in side spray fluid bed, by 15 parts of stearic acid heating and meltings, is sprayed at core while hot
Microcapsule acid B is formed on material A.
(3) 25 parts of phosphoric acid silicon dioxide of 400 mesh is adsorbed, 15 parts of citric acids and 5 parts of fumaric acid is crushed to 120 mesh
Hereinafter, then by the two mix homogeneously powdery acid C is obtained.
(4) microcapsule acid B is placed in dusting pellet processing machine, opens machine, powdery acid C is repeatedly added thereto on a small quantity, while
Spray into 5% dextrin in aqueous solution thereto and make binding agent so that powdery acid C is progressively enriched with the surface for being wrapped in microcapsule acid B, until most
Spherical pellet D is formed eventually completely.
(5) stearic acid of the thawing of its quality 5% is sprayed into in spherical pellet D, obtains final acidulant product.
Embodiment 2：
A kind of preparation method of acidulant is present embodiments provided, following steps are specifically included：
(1) 2 parts of formic acid, 3 parts of acetic acid, 10 parts of lactic acid are mixed, is sprayed into
Even mixing and absorption, obtains core A.
(2) above-mentioned core A is placed in side spray fluid bed, 24 parts of palm stearin heating and meltings is sprayed at while hot
Microcapsule acid B is formed on core A.
(3) 30 parts of lactic acid silicon dioxide of 400 mesh is adsorbed, 10 parts of citric acids and 1 part of fumaric acid is crushed to 120 mesh
Hereinafter, then by the two mix homogeneously powdery acid C is obtained.
(4) microcapsule acid B is placed in dusting pellet processing machine, opens machine, powdery acid C is repeatedly added thereto on a small quantity, while
Spray into 1% methocel solution thereto and make binding agent so that powdery acid C is progressively enriched with the surface for being wrapped in microcapsule acid B, directly
Spherical pellet D is formed completely to final.
(5) palm stearin of the thawing of its quality 10% is sprayed into in spherical pellet D, obtains final acidulant product.
Embodiment 3：
A kind of preparation method of acidulant is present embodiments provided, following steps are specifically included：
(1) 5 parts of acetic acid, 5 parts of propanoic acid, 10 parts of lactic acid are mixed, is sprayed into
Even mixing and absorption, obtains core A.
(2) above-mentioned core A is placed in side spray fluid bed, 25 parts of palm stearin heating and meltings is sprayed at while hot
Microcapsule acid B is formed on core A.
(3) the 15 parts of phosphoric acid and 10 parts of lactic acid silicon dioxide of 400 mesh is adsorbed, by 5 parts of citric acid powders be broken to 120 mesh with
Under, then the two mix homogeneously is obtained powdery acid C.
(4) microcapsule acid B is placed in dusting pellet processing machine, opens machine, powdery acid C is repeatedly added thereto on a small quantity, while
Spray into 2% carboxy-propyl cellulose solution thereto and make binding agent so that powdery acid C is progressively enriched with the surface for being wrapped in microcapsule acid B,
Until final form spherical pellet D completely.
(5) palm stearin of the thawing of its quality 15% is sprayed into in spherical pellet D, obtains final acidulant product.
Exemplified as above is only to illustration of the invention, does not constitute the restriction to protection scope of the present invention, all
It is that design same or analogous with the present invention is belonged within protection scope of the present invention.
Claims (10)
1. a kind of acidulant preparation method, it is characterised in that：Comprise the steps：
1) short-chain fatty acid and lactic acid are mixed, then is adsorbed with carrier one, formed core A；
2) core A is placed in side spray fluid bed, by lipid envelope material heating and melting, is sprayed at core A while hot and is formed
Microcapsule acid B；
3) phosphoric acid and/or lactic acid carrier two are adsorbed, while solid organic acid is crushed, then the two mix homogeneously is obtained powder
Shape acid C；
4) microcapsule acid B is placed in dusting pellet processing machine, is added thereto to powdery acid C, at the same spray into binding agent, make powdery acid C by
Gradually enrichment is wrapped in the surface of microcapsule acid B, until final form spherical pellet D completely；
5) the lipid envelope material for melting is sprayed into spherical pellet D, obtains final product final acidulant product.
2. acidulant preparation method as claimed in claim 1, it is characterised in that：The short-chain fatty acid be formic acid, acetic acid, third
One or more in acid；The short-chain fatty acid mass fraction is 5～15 parts, and lactic acid mass fraction is 0～10 part, carrier one
Mass fraction is 10～20 parts.
3. acidulant preparation method as claimed in claim 1, it is characterised in that：The carrier one is 80～120 purpose of particle diameter
Silicon dioxide, carrier two are the silicon dioxide of below 120 mesh of particle diameter.
4. acidulant preparation method as claimed in claim 1, it is characterised in that：The lipid envelope material include stearic acid,
One or more in stearic acid monoglycerides, palm stearin.
5. acidulant preparation method as claimed in claim 4, it is characterised in that：The microcapsule acid B than core A weightening 40～
80%.
6. acidulant preparation method as claimed in claim 4, it is characterised in that：The step 5) in lipid envelope material matter
Measure 5～15% for spherical pellet D mass.
7. acidulant preparation method as claimed in claim 1, it is characterised in that：The step 3) in solid organic acid be Fructus Citri Limoniae
Acid and/or fumaric acid, and solid organic acid is crushed to below 120 mesh；The phosphoric acid quality number is 0～25 part, lactic acid quality
Number is 0～30 part, and solid organic acid mass fraction is 5～20 parts.
8. acidulant preparation method as claimed in claim 1, it is characterised in that：The step 4) in powdery acid C and microcapsule acid B
Mass ratio be 1:1～1.5.
9. acidulant preparation method as claimed in claim 1, it is characterised in that：The step 4) in binding agent be dextrin, first
The aqueous solution of one or more in base cellulose, carboxy-propyl cellulose；The consumption of binding agent for powdery acid C quality 5～
10%.
10. such as the acidulant of claim 1～9 either method preparation.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107821788A (en) * | 2017-10-18 | 2018-03-23 | 潍坊加易加生物科技有限公司 | Small molecular organic acid type acid supplement coated slow release formulation |
| CN107950808A (en) * | 2017-12-07 | 2018-04-24 | 常州市瑞泰物资有限公司 | A kind of preparation method of the special acidulant of egg feedstuff |
| CN108174978A (en) * | 2017-12-26 | 2018-06-19 | 广州美瑞泰科生物工程技术有限公司 | A kind of acidulant for adjusting stomach health and preparation method thereof |
| CN109566878A (en) * | 2018-12-25 | 2019-04-05 | 乐山市瑞和祥动物保健药业有限公司 | A kind of compound acidulant sustained release pellet and preparation method thereof |
| CN111154477A (en) * | 2020-02-03 | 2020-05-15 | 西南石油大学 | Efficient retarded solid acid system without damage to reservoir |
| CN112868909A (en) * | 2021-01-22 | 2021-06-01 | 湖北神舟化工有限公司 | Odorless sodium butyrate and production method thereof |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101965909A (en) * | 2010-10-20 | 2011-02-09 | 无锡正大畜禽有限公司 | Method for producing coated acidifier granules for feed |
| CN102106461A (en) * | 2010-12-28 | 2011-06-29 | 安徽泰格生物技术股份有限公司 | Enveloping acidifier for feed and preparation method thereof |
| CN103637003A (en) * | 2013-12-02 | 2014-03-19 | 上海美农生物科技股份有限公司 | Preparation method of controlled-release compound type acidifier for pigs |
| CN104187010A (en) * | 2014-09-28 | 2014-12-10 | 重庆民泰香料化工有限责任公司 | Slow release type feed acidifying agent preparing method |
| CN104222630A (en) * | 2014-09-09 | 2014-12-24 | 上海邦成生物工程有限公司 | Coated acidifying agent for feed and preparation method thereof |
| CN104397349A (en) * | 2014-10-31 | 2015-03-11 | 广东绿生源饲料科技有限公司 | Feeding intestinal tract sustained-release type compound acidifier and preparation method thereof |
| CN104719630A (en) * | 2013-12-18 | 2015-06-24 | 上海美农生物科技股份有限公司 | Poultry feed acidifier and preparation method thereof |
| CN105724821A (en) * | 2016-03-04 | 2016-07-06 | 江苏省家禽科学研究所 | Chicken feed composite acidifier as well as preparation method and application thereof |
-
2016
- 2016-09-20 CN CN201610830843.3A patent/CN106490345A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101965909A (en) * | 2010-10-20 | 2011-02-09 | 无锡正大畜禽有限公司 | Method for producing coated acidifier granules for feed |
| CN102106461A (en) * | 2010-12-28 | 2011-06-29 | 安徽泰格生物技术股份有限公司 | Enveloping acidifier for feed and preparation method thereof |
| CN103637003A (en) * | 2013-12-02 | 2014-03-19 | 上海美农生物科技股份有限公司 | Preparation method of controlled-release compound type acidifier for pigs |
| CN104719630A (en) * | 2013-12-18 | 2015-06-24 | 上海美农生物科技股份有限公司 | Poultry feed acidifier and preparation method thereof |
| CN104222630A (en) * | 2014-09-09 | 2014-12-24 | 上海邦成生物工程有限公司 | Coated acidifying agent for feed and preparation method thereof |
| CN104187010A (en) * | 2014-09-28 | 2014-12-10 | 重庆民泰香料化工有限责任公司 | Slow release type feed acidifying agent preparing method |
| CN104397349A (en) * | 2014-10-31 | 2015-03-11 | 广东绿生源饲料科技有限公司 | Feeding intestinal tract sustained-release type compound acidifier and preparation method thereof |
| CN105724821A (en) * | 2016-03-04 | 2016-07-06 | 江苏省家禽科学研究所 | Chicken feed composite acidifier as well as preparation method and application thereof |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107821788A (en) * | 2017-10-18 | 2018-03-23 | 潍坊加易加生物科技有限公司 | Small molecular organic acid type acid supplement coated slow release formulation |
| CN107950808A (en) * | 2017-12-07 | 2018-04-24 | 常州市瑞泰物资有限公司 | A kind of preparation method of the special acidulant of egg feedstuff |
| CN108174978A (en) * | 2017-12-26 | 2018-06-19 | 广州美瑞泰科生物工程技术有限公司 | A kind of acidulant for adjusting stomach health and preparation method thereof |
| CN109566878A (en) * | 2018-12-25 | 2019-04-05 | 乐山市瑞和祥动物保健药业有限公司 | A kind of compound acidulant sustained release pellet and preparation method thereof |
| CN111154477A (en) * | 2020-02-03 | 2020-05-15 | 西南石油大学 | Efficient retarded solid acid system without damage to reservoir |
| CN111154477B (en) * | 2020-02-03 | 2020-07-31 | 西南石油大学 | Efficient retarded solid acid system without damage to reservoir |
| CN112868909A (en) * | 2021-01-22 | 2021-06-01 | 湖北神舟化工有限公司 | Odorless sodium butyrate and production method thereof |
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Application publication date: 20170315 |