CN106483480A - Based on single probe biological magnetic field detection method of GMI effect, circuit and sensor - Google Patents

Based on single probe biological magnetic field detection method of GMI effect, circuit and sensor Download PDF

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Publication number
CN106483480A
CN106483480A CN201610849945.XA CN201610849945A CN106483480A CN 106483480 A CN106483480 A CN 106483480A CN 201610849945 A CN201610849945 A CN 201610849945A CN 106483480 A CN106483480 A CN 106483480A
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magnetic field
low
gmi
circuit
pass filter
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CN106483480B (en
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周宗潭
胡德文
王志华
徐�明
郭善磁
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National University of Defense Technology
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National University of Defense Technology
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/02Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/06Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
    • G01R33/09Magnetoresistive devices
    • G01R33/093Magnetoresistive devices using multilayer structures, e.g. giant magnetoresistance sensors

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  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The invention discloses based on single probe biological magnetic field detection method of GMI effect, circuit and sensor, after method and step includes that the output signal that amorphous wire GMI pops one's head in is divided into independent and non-interfering two-way and is respectively adopted the different low pass filter filtering of cut-off frequency, then carry out differential amplification and obtain biological magnetic field detectable signal;Circuit includes isolation circuit, the first low-pass filter unit, the second low-pass filter unit and differential amplification unit;Sensor includes amorphous wire GMI probe and aforementioned circuit.The present invention by single amorphous wire GMI pop one's head in output induced signal isolation separation become two-way can the signal of independent process carry out differential amplification after low-pass filtering treatment respectively, the interference in homogeneous magnetic field in environment can be excluded, play the preposition effect of High frequency filter, without the concern for amorphous wire material coherence request, be easy to miniaturization, integrated, good have the advantages that adaptability.

Description

Based on single probe biological magnetic field detection method of GMI effect, circuit and sensor
Technical field
The present invention relates to biological magnetic field Detection Techniques, and in particular to a kind of single probe biological magnetic field based on GMI effect is visited Survey method, circuit and sensor.
Background technology
GMI effect, i.e. giant magnetoresistance effect, when silk or the bar of soft magnetic material (mostly Co base amorphous and Fe base nanometer crystal) Band passes to alternating current IacWhen, the alternating voltage U at material two endswWith external magnetic field H added by silk longitudinal directionexChange and sensitive change The phenomenon of change, its essence is the sensitive change of the impedance with externally-applied magnetic field of amorphous wire itself.Designed based on non-crystalline material GMI effect Magnetic Sensor there is good weak magnetic detection performance, detection accuracy can be used for extremely faint under unshielded environments up to pT level Detection of biological magnetic field, such as biological magnetic field etc..
Usual non-diagonal mode of the weak magnetic sensor designed based on GMI effect popping one's head in is designed, as shown in figure 1, adopting high frequency Sine wave or spike current signal iwDrive amorphous wire, it will make amorphous wire that GMI effect is produced, now the magnetic of Axial changes Field will cause the change of amorphous wire impedance, by being enclosed in the induction coil on amorphous wire surface, can be by the impedance of amorphous wire Change is converted to the induced electromotive force E of induction coil outputcoilChange.Now, exporting induced electromotive force by measuring coil is The change of corresponding external magnetic field can be extrapolated.
Based on the design of amorphous wire GMI effect when can be used for detecting biological low-intensity magnetic field sensor, its detectivity is needed Reach pT level.GMI sensor is designed using off-diagonal mode, its detectivity is extremely difficult to when using a probe PT level, generally designs magnetic field gradient meter by the way of the difference of space to realize the detection in pT level magnetic field, i.e., using two amorphous Material separately designs two probes and is placed on different locus, homogeneous magnetic field in such environment(Such as earth's magnetic field etc.)Will be Same impedance change is produced in two probes.If two probes are placed on different locus, one is placed on magnetic field sources to be measured Near, another away from magnetic field sources to be measured, two probe outputs are carried out difference and is synthesized and is amplified, can thus arrange Except the interference in homogeneous magnetic field in environment, the signal of output correspond only to magnetic source variation magnetic field and cause induced electromotive force, this side is used Method can realize the detection in pT level magnetic field, and probe schematic diagram is as shown in Fig. 2 wherein Coil1 and Coil2 represent two probes respectively Induction coil,E coil1WithE coil2Represent the induced electromotive force of the induction coil output of two probes respectively(It is connected respectively to The analog switch SH1 of back-end circuit and SH2 connection terminal),LRepresent two probe induction coils between distance certain away from From,PE represents the signal for driving amorphous wire, and G represents ground connection.But, above-mentioned employing space differential mode designs magnetic field gradient meter To realize pT level detection of magnetic field, which is very high to the coherence request that pops one's head in, and main is exactly to require that two sections of amorphous wires are electrically special Property is extremely consistent.Generally amorphous wire is in production, it is difficult to accomplish good uniformity, even if two sections of amorphous wires of same batch are electric Characteristic has been likely to than larger difference, is so caused when difference detector design is done, it is necessary to devote a tremendous amount of time choosing Two sections of extremely close amorphous wires of electrical characteristic are selected, the induction electric that otherwise homogeneous magnetic field will be produced in two probes will definitely Inconsistent, the range of Magnetic Sensor can be not only reduced during tens thousand of times of such differential amplification, be easy to cause sensor defeated when serious Go out saturation.Secondly in space parallax timesharing, two probe distances generally need to reach more than 3 centimetres, so can just make pT The induced electromotive force that the magnetic source of level change is produced in two probes has larger difference, when sensor integration, body Product is also very big, be extremely unfavorable for the miniaturization of amorphous wire GMI Magnetic Sensor with integrated.
Content of the invention
The technical problem to be solved in the present invention:For the problems referred to above of prior art, a kind of list based on GMI effect is provided Probe biological magnetic field detection method, circuit and sensor, the induced signal of single probe is become two-way mutually not through isolation separation The signal of interference carries out differential amplification after carrying out different low-pass filtering treatment respectively again, so can be used for excluding in environment all The interference in one magnetic field, plays the preposition effect of High frequency filter, it is possible to do not consider amorphous wire material coherence request, be easy to GMI Sensor miniaturization, integrated.
In order to solve above-mentioned technical problem, the technical solution used in the present invention is:
A kind of single probe biological magnetic field detection method based on GMI effect, step include:
1)The output signal isolation of amorphous wire GMI probe detection signal output part is separated into independent and non-interfering two-way letter Number;
2)One tunnel output signal is carried out cut-off frequency than high low of higher limit that detect target organism field signal frequency separation Pass filter, another road output signal carry out cut-off frequency than low low of lower limit for detecting target organism field signal frequency separation Pass filter;
3)Signal of the two-way after low-pass filtered is carried out differential amplification and obtains biological magnetic field detectable signal.
Preferably, the step 1)The middle output signal isolation that amorphous wire GMI pops one's head in is separated into independent two paths of signals Specifically refer to:Toward the reference voltage connection end input reference voltage of amorphous wire GMI probe, the detection letter that amorphous wire GMI is popped one's head in The voltage of number output end output is exported respectively to the anode of two diodes, using the negative electrode of two diodes as independent and The output connection end of non-interfering two paths of signals.
The present invention also provides a kind of single probe biological magnetic field detection circuit based on GMI effect, including isolation circuit, first Low-pass filter unit, the second low-pass filter unit and differential amplification unit, the input of the isolation circuit and amorphous wire GMI are visited The detectable signal output end of head is connected, an output end of the isolation circuit and the input phase of the first low-pass filter unit Even, another output end is connected with the input of the second low-pass filter unit, the input of the differential amplification unit respectively with First low-pass filter unit, the second low-pass filter unit are connected, and the cut-off frequency of first low-pass filter unit is than detection mesh The interval higher limit of mark biological magnetic field signal frequency is high, and the cut-off frequency of second low-pass filter unit is than detection target organism The lower limit of field signal frequency separation is low.
Preferably, the isolation circuit includes N balanced potentiometer RP, diode D1 and diode D2, N balanced potentiometer RPA fixing termination power VCC, another fixing end ground connection or reference potential, tune The reference voltage connection end that section end is popped one's head in amorphous wire GMI is connected, and the anode of the anode of diode D1 and diode D2 connects jointly It is connected to the detectable signal output end of amorphous wire GMI probe, the input phase of the negative electrode of diode D1 and the first low-pass filter unit Even, the input of the negative electrode of diode D2 and the second low-pass filter unit is connected.
Preferably, first low-pass filter unit includes electric capacity C1, resistance R1 and resistance R2, and resistance R2 is serially connected with two poles Between the negative electrode of pipe D1, an input of differential amplification unit, one end of resistance R1 is connected to the negative electrode of diode D1, resistance Between R2, the other end of resistance R1 ground connection or reference potential, one end of electric capacity C1 be connected to resistance R2, the one of differential amplification unit Between individual input, the other end of electric capacity C1 is grounded or reference potential.
Preferably, second low-pass filter unit includes electric capacity C2, resistance R3 and resistance R4, and resistance R4 is serially connected with two poles Between the negative electrode of pipe D2, another input of differential amplification unit, one end of resistance R3 is connected to the negative electrode of diode D2, electricity Between resistance R4, the other end of resistance R3 ground connection or reference potential, one end of electric capacity C2 are connected to resistance R4, differential amplification unit Between another input, the other end of electric capacity C2 is grounded or reference potential.
Preferably, the differential amplification unit includes that differential amplification module and multiplication factor adjust resistance RG, the difference Amplification module includes two groups of inputs and an output end for exporting biological magnetic field detectable signal, and each group of input includes Two connection terminals, a connection terminal of first group of input and the output end of the first low-pass filter unit are connected, second group The output end of one connection terminal of input and the second low-pass filter unit is connected, and another terminal of first group of input leads to Cross multiplication factor and adjust resistance RGDirectly it is connected with another connection terminal of second group of input.
The present invention also provides a kind of single probe biological magnetic field detection sensor based on GMI effect, visits including amorphous wire GMI Head, spike produce circuit, primary signal conditioning amplifying circuit, second signal conditioning amplifying circuit and three-level signal conditioning and amplify Circuit, the primary signal conditioning amplifying circuit are aforementioned single probe biological magnetic field detection circuit based on GMI effect, described non- Brilliant silk GMI probe includes that amorphous wire, induction coil, analog switch and detection electric capacity, described amorphous wire one end and spike are produced The output end of circuit is connected, other end ground connection, and the induction coil is set around on amorphous wire, the induction coil, analog switch, Detection electric capacity three join end to end to form loop, and the detection electric capacity is to visit as amorphous wire GMI near one end of analog switch The detectable signal output end of head, other end connection end as the reference voltage, the second signal conditioning amplifying circuit include trap Wave filter and two grades of isolating amplifier circuits, the three-level signal conditioning amplifying circuit include that bandpass filter and three-level isolation are amplified Circuit, the isolation circuit of single probe biological magnetic field detection circuit are connected with induction coil, and single probe biological magnetic field is visited The output end of slowdown monitoring circuit and notch filter, two grades of isolating amplifier circuits, bandpass filter, three-level isolating amplifier circuits phase successively Even.
The present invention is had the advantage that based on single probe biological magnetic field detection method tool of GMI effect:
1st, by analysis, homogeneous magnetic field is mainly earth's magnetic field, and when amorphous wire GMI probe orientation is fixed, these magnetic fields will Constant impedance variations can be produced in amorphous wire, the output corresponding to induction coil will be stable DC part.By amorphous wire The output signal isolation of GMI probe is separated into independent two paths of signals, it is ensured that two paths of signals is separate and does not interfere with each other, then By a road output signal carry out cut-off frequency than detect target organism field signal frequency separation the high LPF of higher limit, Another road output signal carries out the cut-off frequency LPF lower than the lower limit for detecting target organism field signal frequency separation, So that equal stable DC part comprising environmental magnetic field in signal after two-way is low-pass filtered, and a road is comprising biological magnetic field spy Survey signal, another road and do not include biological magnetic field detectable signal, signal of the two-way after low-pass filtered is carried out differential amplification and is obtained After biological magnetic field detectable signal, on the one hand can be by the stable DC partial offset of environmental magnetic field, so as to the environmental magnetic field that is eliminated Biological magnetic field detectable signal, on the other hand also function to the preposition effect of High frequency filter, play filtering environmental high frequency signal Effect.
2nd, the present invention only needs to single amorphous wire GMI probe and can achieve, therefore, it is possible to overcome prior art using two Magnetic field during probe difference near two probes may also have other magnetic interference in addition to homogeneous magnetic field, therefore differential amplification When without the concern for amorphous wire material coherence request, be easy to miniaturization, integrated, good have the advantages that adaptivity.
The present invention is based on single probe biological magnetic field detection circuit of GMI effect, the single probe biological magnetic field based on GMI effect Detection sensor is single the pop one's head in corresponding circuit of biological magnetic field detection method or transducer arrangement configuration based on GMI effect, Single probe biological magnetic field detection based on GMI effect can achieve by the structure of its circuit or sensor, therefore equally also have There are aforementioned advantages of the present invention based on single probe biological magnetic field detection method of GMI effect, therefore will not be described here.
Description of the drawings
Fig. 1 is existing based on GMI effect biological magnetic field sensor probe principle schematic.
Fig. 2 is prior art dual probe magnetic field gradient meter principle schematic.
Fig. 3 is the basic procedure schematic diagram of present invention method.
Fig. 4 is the circuit theory schematic diagram of embodiment of the present invention list probe biological magnetic field detection circuit.
Fig. 5 is the sensor construction schematic diagram for applying the embodiment of the present invention.
Marginal data:1st, isolation circuit;2nd, low-pass filter unit;3rd, the second low-pass filter unit;4th, differential amplification unit; 5th, amorphous wire GMI probe;51st, amorphous wire;52nd, induction coil;53rd, analog switch;54th, detection electric capacity;6th, spike produces electricity Road;7th, primary signal conditioning amplifying circuit;8th, second signal conditioning amplifying circuit;81st, notch filter;82nd, two grades of isolation are put Big circuit;9th, three-level signal conditioning amplifying circuit;91st, bandpass filter;92nd, three-level isolating amplifier circuit.
Specific embodiment
As shown in figure 3, the present embodiment is included based on single probe biological magnetic field detection method step of GMI effect:
1)The output signal isolation of amorphous wire GMI probe detection signal output part is separated into independent and non-interfering two-way letter Number;
2)One tunnel output signal is carried out cut-off frequency than high low of higher limit that detect target organism field signal frequency separation Pass filter, another road output signal carry out cut-off frequency than low low of lower limit for detecting target organism field signal frequency separation Pass filter;
3)Signal of the two-way after low-pass filtered is carried out differential amplification and obtains biological magnetic field detectable signal.
It should be noted that as different types of detection target organism field signal frequency is different, such as core field letter Number, brain field signal, muscle field signal etc., therefore corresponding detection target organism field signal frequency separation is not yet Same, in actual application, can be determined according to the detection target organism field signal frequency separation of amorphous wire GMI probe The cut-off frequency of two-way LPF, a road output signal is carried out cut-off frequency than detection target organism field signal frequency zones Between the high LPF of higher limit, another road output signal carry out cut-off frequency than detection target organism field signal frequency zones Between the low LPF of lower limit.
It should be noted that different detection target organism magnetic field has different detection target organism field signal frequencies Interval.In the present embodiment, step 2)In carry out cut-off frequency than detect target organism field signal frequency separation higher limit high LPF when, now DC component is not also filtered out and is retained, and detect target organism field signal also can be by Retain;Step 2)In carry out cut-off frequency than detect target organism field signal frequency separation lower limit low LPF when So in probe signal, DC component will be retained, and detect target organism field signal and be then filtered out.By above-mentioned setting, When two paths of signals difference, it is possible to which the interference for excluding homogeneous magnetic field in environment ensures that biological magnetic field signal to be detected is protected Stay.
In the present embodiment, step 1)The middle output signal isolation that amorphous wire GMI pops one's head in is separated into independence and does not interfere with each other Two paths of signals specifically refer to:Toward the reference voltage connection end input reference voltage of amorphous wire GMI probe, amorphous wire GMI is visited The voltage of the detectable signal output end output of head is exported respectively to the anode of two diodes, and the negative electrode of two diodes is distinguished Output connection end as independent and non-interfering two paths of signals.By the way, simply, easily can realize will be non- The output signal isolation of brilliant silk GMI probe is separated into independent two paths of signals, and will not be mutual when exerting oneself to two paths of signals Interference.Certainly, under conditions of cost is not considered, it would however also be possible to employ including the isolation circuit including optocoupler, which is equally The output signal isolation that can realize amorphous wire GMI pops one's head in is separated into independent two paths of signals, will not be described here.
As shown in figure 4, the present embodiment based on single probe biological magnetic field detection circuit of GMI effect include isolation circuit 1, the One low-pass filter unit 2, the second low-pass filter unit 3 and differential amplification unit 4, the input of isolation circuit 1 and amorphous wire GMI The detectable signal output end of probe is connected, an output end of isolation circuit 1 and the input phase of the first low-pass filter unit 2 Even, another output end is connected with the input of the second low-pass filter unit 3, and the input of differential amplification unit 4 is respectively with the One low-pass filter unit 2, the second low-pass filter unit 3 are connected, and the cut-off frequency of the first low-pass filter unit 1 is than detection target life The higher limit of thing field signal frequency separation is high, and the cut-off frequency of the second low-pass filter unit 2 is than detection target organism magnetic field letter The lower limit of number frequency separation is low.
As shown in figure 4, isolation circuit 1 includes N balanced potentiometer RP, diode D1 and diode D2, N balanced potentiometer RPA fixing termination power VCC, another fixing end ground connection or reference potential, tune The reference voltage connection end that section end is popped one's head in amorphous wire GMI is connected, and the anode of the anode of diode D1 and diode D2 connects jointly It is connected to the detectable signal output end of amorphous wire GMI probe, the input phase of the negative electrode of diode D1 and the first low-pass filter unit 2 Even, the input of the negative electrode of diode D2 and the second low-pass filter unit 3 is connected.N balanced potentiometer RPWith Reference voltage is improved, the conduction voltage drop of diode D1 and diode D2 is offset so that diode is in pre- conducting state, even if The induced electricity electromotive force for obtaining amorphous wire GMI probe can be passed in subsequent conditioning circuit by diode D1 and diode D2.Consider The conduction voltage drop about 0.1V of diode D1 and diode D20.7V, amorphous wire GMI probe, therefore in the present embodiment, diode is led Logical pressure drop balanced potentiometer RPAdjustable side output voltage be more than 0.8V such that it is able to guarantee offset diode D1 and diode D2 Conduction voltage drop so that diode be in pre- conducting state.
As shown in figure 4, the first low-pass filter unit 2 includes electric capacity C1, resistance R1 and resistance R2, resistance R2 is serially connected with two poles Between the negative electrode of pipe D1, an input of differential amplification unit 4, one end of resistance R1 is connected to the negative electrode of diode D1, electricity Between resistance R2, the other end of resistance R1 is grounded or reference potential, and one end of electric capacity C1 is connected to resistance R2, differential amplification unit 4 An input between, the other end of electric capacity C1 ground connection or reference potential.The effect of low pass filter is exactly to be believed by low frequency Number, filter high-frequency signal, electric capacity C1, resistance R1 and resistance R2 composition passive low ventilating filter ,-the 3dB of passive low ventilating filter Cut-off frequency f01Meet formula f01=1/(2πR2C1), wherein R2For the resistance value of resistance R2, C1Capacitance for electric capacity C1.
As shown in figure 4, the second low-pass filter unit 3 includes electric capacity C2, resistance R3 and resistance R4, resistance R4 is serially connected with two poles Between the negative electrode of pipe D2, another input of differential amplification unit 4, one end of resistance R3 be connected to the negative electrode of diode D2, Between resistance R4, the other end of resistance R3 is grounded or reference potential, and one end of electric capacity C2 is connected to resistance R4, differential amplification unit Between 4 another input, the other end of electric capacity C2 is grounded or reference potential.Second low-pass filter circuit 3 and the first low pass 2 structure of filter circuit is identical, and simply cut-off frequency is different, in the present embodiment, the cut-off frequency f of the second low-pass filter circuit 302Full Sufficient formula f02=1/(2πR3C2), wherein R3For the resistance value of resistance R3, C2Capacitance for electric capacity C2.R1=R3 in the present embodiment, Conducting resistance in view of diode D1 and D2 is greater than 6k Ω for the resistance of 400 ~ 600 Ω, R1 and R3.
As shown in figure 4, differential amplification unit 4 includes that differential amplification module and multiplication factor adjust resistance RG, differential amplification Module includes two groups of inputs and an output end for exporting biological magnetic field detectable signal, and each group of input includes two Connection terminal, a connection terminal of first group of input and the output end of the first low-pass filter unit 2 are connected, second group of input The output end of one connection terminal at end and the second low-pass filter unit 3 is connected, and another terminal of first group of input passes through Multiplication factor adjusts resistance RG and is directly connected with another connection terminal of second group of input.In the present embodiment, differential amplification Module is specifically realized using instrument amplifier, in addition can also be using other differential amplification computing chips or voluntarily using computing Realization built by amplifier.
The present embodiment both individually can be sold based on single probe biological magnetic field detection circuit of GMI effect, in addition it is also possible to The present embodiment is directly integrated into single probe biological magnetic field detection sensing based on single probe biological magnetic field detection circuit of GMI effect In device.
As shown in figure 5, being integrated with single probe life of the present embodiment based on single probe biological magnetic field detection circuit of GMI effect Thing detection of magnetic field sensor includes that amorphous wire GMI probe 5, spike produces circuit 6, primary signal 7, two grades of amplifying circuit of conditioning Signal condition amplifying circuit 8 and three-level signal conditioning amplifying circuit 9, primary signal conditioning amplifying circuit 7 is that the present embodiment is aforementioned Based on single probe biological magnetic field detection circuit of GMI effect, amorphous wire GMI probe 5 includes amorphous wire 51, induction coil 52, mould Intend switch 53 and electric capacity 54, the output end that 51 one end of amorphous wire produces circuit 6 with spike is connected, other end ground connection, the line of induction Circle 52 is set around on amorphous wire 51, and induction coil 52, analog switch 53,54 three of electric capacity join end to end to form loop, detection electricity Detectable signal output end of the appearance 54 using one end of close analog switch 53 as amorphous wire GMI probe 5, the other end are used as reference electricity Pressure connection end, second signal conditioning amplifying circuit 8 include notch filter 81(50Hz)With two grades of isolating amplifier circuits 82, three-level Signal condition amplifying circuit 9 includes bandpass filter 91 and three-level isolating amplifier circuit 92, single probe biological magnetic field detection circuit Isolation circuit 1 be connected with induction coil 52, the output end of single probe biological magnetic field detection circuit and 81, two grades of notch filter Isolating amplifier circuit 82, bandpass filter 91, three-level isolating amplifier circuit 92 are sequentially connected.Due to amorphous wire GMI probe 5 defeated Go out signal very weak, it is therefore desirable to amplifying circuit 7, second signal is nursed one's health by primary signal and nurses one's health amplifying circuit 8 and three-level signal Conditioning amplifying circuit 9 is amplified step by step, and so as to finally give the amplification of 100,000 times of ranks or so, wherein notch filter 81 is used In the impact for excluding Hz noise in environment, bandpass filter 91 is used for the effect of exclusive PCR, so that it is guaranteed that amplified signal Accuracy.
The above is only the preferred embodiment of the present invention, and protection scope of the present invention is not limited merely to above-mentioned enforcement Example, all technical schemes belonged under thinking of the present invention belong to protection scope of the present invention.It should be pointed out that for the art Those of ordinary skill for, some improvements and modifications without departing from the principles of the present invention, these improvements and modifications Should be regarded as protection scope of the present invention.

Claims (8)

1. a kind of single probe biological magnetic field detection method based on GMI effect, it is characterised in that step includes:
1)The output signal isolation of amorphous wire GMI probe detection signal output part is separated into independent and non-interfering two-way letter Number;
2)One tunnel output signal is carried out cut-off frequency than high low of higher limit that detect target organism field signal frequency separation Pass filter, another road output signal carry out cut-off frequency than low low of lower limit for detecting target organism field signal frequency separation Pass filter;
3)Signal of the two-way after low-pass filtered is carried out differential amplification and obtains biological magnetic field detectable signal.
2. the single probe biological magnetic field detection method based on GMI effect according to claim 1, it is characterised in that described Step 1)The middle output signal isolation that amorphous wire GMI pops one's head in is separated into independent two paths of signals and specifically refers to:Toward amorphous wire GMI The reference voltage connection end input reference voltage of probe, the voltage of the detectable signal output end output that amorphous wire GMI is popped one's head in divide Do not export to the anode of two diodes, using the negative electrode of two diodes as independent and non-interfering two paths of signals Output connection end.
3. a kind of single probe biological magnetic field detection circuit based on GMI effect, it is characterised in that:Including isolation circuit(1), first Low-pass filter unit(2), the second low-pass filter unit(3)And differential amplification unit(4), the isolation circuit(1)Input It is connected with the detectable signal output end of amorphous wire GMI probe, the isolation circuit(1)An output end and the first LPF Unit(2)Input be connected, another output end and the second low-pass filter unit(3)Input be connected, the difference is put Big unit(4)Input respectively with the first low-pass filter unit(2), the second low-pass filter unit(3)It is connected, described first is low Pass filtering unit(1)Cut-off frequency than detect target organism field signal frequency separation higher limit high, second low pass Filter unit(2)Cut-off frequency than detect target organism field signal frequency separation lower limit low.
4. the single probe biological magnetic field detection circuit based on GMI effect according to claim 3, it is characterised in that:Described Isolation circuit(1)Including N balanced potentiometer RP, diode D1 and diode D2, N put down Weighing apparatus potentiometer RPA fixing termination power VCC, another fixing end ground connection or reference potential, adjustable side and amorphous wire GMI The reference voltage connection end of probe is connected, and the anode of the anode of diode D1 and diode D2 is commonly connected to amorphous wire GMI spy The detectable signal output end of head, the negative electrode of diode D1 and the first low-pass filter unit(2)Input be connected, diode D2 Negative electrode and the second low-pass filter unit(3)Input be connected.
5. the single probe biological magnetic field detection circuit based on GMI effect according to claim 3, it is characterised in that:Described First low-pass filter unit(2)Including electric capacity C1, resistance R1 and resistance R2, resistance R2 is serially connected with the negative electrode of diode D1, difference Amplifying unit(4)An input between, one end of resistance R1 is connected between the negative electrode of diode D1, resistance R2, resistance The other end ground connection of R1 or reference potential, one end of electric capacity C1 is connected to resistance R2, differential amplification unit(4)An input Between, the other end of electric capacity C1 is grounded or reference potential.
6. the single probe biological magnetic field detection circuit based on GMI effect according to claim 3, it is characterised in that:Described Second low-pass filter unit(3)Including electric capacity C2, resistance R3 and resistance R4, resistance R4 is serially connected with the negative electrode of diode D2, difference Amplifying unit(4)Another input between, one end of resistance R3 is connected between the negative electrode of diode D2, resistance R4, electricity The other end ground connection of resistance R3 or reference potential, one end of electric capacity C2 is connected to resistance R4, differential amplification unit(4)Another is defeated Enter between end, the other end of electric capacity C2 is grounded or reference potential.
7. the single probe biological magnetic field detection circuit based on GMI effect according to claim 3, it is characterised in that described Differential amplification unit(4)Resistance R is adjusted including differential amplification module and multiplication factorG, the differential amplification module includes two groups Input and an output end for being used for exporting biological magnetic field detectable signal, each group of input include two connection terminals, the One connection terminal of one group of input and the first low-pass filter unit(2)Output end be connected, one of second group of input Connection terminal and the second low-pass filter unit(3)Output end be connected, another terminal of first group of input passes through times magnification Number adjusts resistance RGDirectly it is connected with another connection terminal of second group of input.
8. a kind of single probe biological magnetic field detection sensor based on GMI effect, pops one's head in including amorphous wire GMI(5), spike produce Raw circuit(6), primary signal conditioning amplifying circuit(7), second signal conditioning amplifying circuit(8)Amplify electricity with three-level signal conditioning Road(9), it is characterised in that:The primary signal nurses one's health amplifying circuit(7)Base described in any one in claim 4~9 In single probe biological magnetic field detection circuit of GMI effect, the amorphous wire GMI probe(5)Including amorphous wire(51), induction coil (52), analog switch(53)With detection electric capacity(54), the amorphous wire(51)One end and spike produce circuit(6)Output end It is connected, the other end is grounded, the induction coil(52)It is set around amorphous wire(51)On, the induction coil(52), analog switch (53), detection electric capacity(54)Three joins end to end to form loop, the detection electric capacity(54)With near analog switch(53)One End is popped one's head in as amorphous wire GMI(5)Detectable signal output end, other end connection end as the reference voltage, the second signal Conditioning amplifying circuit(8)Including notch filter(81)With two grades of isolating amplifier circuits(82), the three-level signal conditioning amplification Circuit(9)Including bandpass filter(91)With three-level isolating amplifier circuit(92), single probe biological magnetic field detection circuit Isolation circuit(1)And induction coil(52)It is connected, the output end of single probe biological magnetic field detection circuit and notch filter (81), two grades of isolating amplifier circuits(82), bandpass filter(91), three-level isolating amplifier circuit(92)It is sequentially connected.
CN201610849945.XA 2016-09-26 2016-09-26 Single probe biological magnetic field detection method, circuit and sensor based on GMI effect Active CN106483480B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110446922A (en) * 2017-04-10 2019-11-12 普乐福尼克迪特布什有限责任公司 Differential probe, detection device and manufacturing method
WO2020113467A1 (en) * 2018-12-05 2020-06-11 中国科学院地质与地球物理研究所 Inductive magnetic sensor and electromagnetic exploration device
CN112698251A (en) * 2020-11-12 2021-04-23 中国电子产品可靠性与环境试验研究所((工业和信息化部电子第五研究所)(中国赛宝实验室)) Magnetic field passive probe and magnetic field detection device
CN112729247A (en) * 2020-12-15 2021-04-30 李艳 Ground-air complementary remote sensing measurement method based on computer communication
CN116068290A (en) * 2023-03-02 2023-05-05 青岛鼎信通讯股份有限公司 Power frequency signal acquisition method for low-voltage nuclear phase instrument

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090224755A1 (en) * 2004-11-30 2009-09-10 Koninklijke Philips Electronics, N.V. Means and method for sensing a magnetic stray field in biosensors
CN103023445A (en) * 2010-05-10 2013-04-03 国民技术股份有限公司 Differential analog front end device used for low-frequency signal detection and transmission system
CN203310984U (en) * 2013-05-03 2013-11-27 中国地震局地球物理研究所 Bridge type resistor giant magneto-impedance effect magnetic field sensor
CN104980217A (en) * 2015-06-19 2015-10-14 邹骁 Visible light communication system and method, and associated device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090224755A1 (en) * 2004-11-30 2009-09-10 Koninklijke Philips Electronics, N.V. Means and method for sensing a magnetic stray field in biosensors
CN103023445A (en) * 2010-05-10 2013-04-03 国民技术股份有限公司 Differential analog front end device used for low-frequency signal detection and transmission system
CN203310984U (en) * 2013-05-03 2013-11-27 中国地震局地球物理研究所 Bridge type resistor giant magneto-impedance effect magnetic field sensor
CN104980217A (en) * 2015-06-19 2015-10-14 邹骁 Visible light communication system and method, and associated device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨慧等: "基于巨磁阻抗效应的微磁传感器设计与实现", 《微纳电子技术》 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110446922A (en) * 2017-04-10 2019-11-12 普乐福尼克迪特布什有限责任公司 Differential probe, detection device and manufacturing method
CN110446922B (en) * 2017-04-10 2024-04-02 普乐福尼克迪特布什有限责任公司 Differential probe, probe device and manufacturing method
WO2020113467A1 (en) * 2018-12-05 2020-06-11 中国科学院地质与地球物理研究所 Inductive magnetic sensor and electromagnetic exploration device
US11914092B2 (en) 2018-12-05 2024-02-27 Institute Of Geology And Geophysics, The Chinese Academy Of Sciences Inductive magnetic sensor and electromagnetic prospecting equipment
CN112698251A (en) * 2020-11-12 2021-04-23 中国电子产品可靠性与环境试验研究所((工业和信息化部电子第五研究所)(中国赛宝实验室)) Magnetic field passive probe and magnetic field detection device
CN112698251B (en) * 2020-11-12 2023-08-04 中国电子产品可靠性与环境试验研究所((工业和信息化部电子第五研究所)(中国赛宝实验室)) Magnetic field passive probe and magnetic field detection device
CN112729247A (en) * 2020-12-15 2021-04-30 李艳 Ground-air complementary remote sensing measurement method based on computer communication
CN116068290A (en) * 2023-03-02 2023-05-05 青岛鼎信通讯股份有限公司 Power frequency signal acquisition method for low-voltage nuclear phase instrument

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