CN106483480B - Single probe biological magnetic field detection method, circuit and sensor based on GMI effect - Google Patents
Single probe biological magnetic field detection method, circuit and sensor based on GMI effect Download PDFInfo
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- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
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- G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
- G01R33/06—Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
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Abstract
The invention discloses single probe biological magnetic field detection method, circuit and sensors based on GMI effect, method and step includes after the output signal that amorphous wire GMI pops one's head in be divided into independent and non-interfering two-way and the different low-pass filter filtering of cutoff frequency is respectively adopted, then carrying out differential amplification and obtaining biological magnetic field detectable signal;Circuit includes isolation circuit, the first low-pass filter unit, the second low-pass filter unit and differential amplification unit;Sensor includes amorphous wire GMI probe and aforementioned circuit.The present invention by the inductive signal isolation separation of single amorphous wire GMI probe output become two-way can the signal of independent process carry out differential amplification after low-pass filtering treatment respectively, it can exclude the interference in uniform magnetic field in environment, play the preposition effect of High frequency filter, without the concern for amorphous wire material coherence request, convenient for micromation, integrated, adaptable good advantage.
Description
Technical field
The present invention relates to biological magnetic field Detection Techniques, and in particular to a kind of single probe biological magnetic field spy based on GMI effect
Survey method, circuit and sensor.
Background technique
GMI effect, i.e. giant magnetoresistance effect, when the silk or item of soft magnetic material (mostly Co base amorphous and Fe base nanometer crystal)
Band passes to alternating current IacWhen, the alternating voltage U of material endswWith external magnetic field H added by silk longitudinal directionexVariation and sensitive change
The phenomenon that change, its essence is the impedances of amorphous wire itself with the sensitive variation of externally-applied magnetic field.It is designed based on non-crystalline material GMI effect
Magnetic Sensor there is good weak magnetic detection performance, detection accuracy can be used for extremely faint under unshielded environments up to pT grades
Detection of biological magnetic field, such as biological magnetic field etc..
Usual non-diagonal mode of weak magnetic sensor based on the design of GMI effect popping one's head in designs, as shown in Figure 1, using high frequency
Sine wave or sharp pulse current signal iwDrive amorphous wire, it will so that amorphous wire is generated GMI effect, at this time the magnetic of Axial changes
Field will cause the variation of amorphous wire impedance can be by the impedance of amorphous wire by being enclosed in the induction coil on amorphous wire surface
Variation is converted to the induced electromotive force E of induction coil outputcoilVariation.At this point, being by measuring coil output induced electromotive force
Corresponding external magnetic field variation can be extrapolated.
Based on the design of amorphous wire GMI effect when can be used for detecting biological low-intensity magnetic field sensor, detectivity is needed
Reach pT grades.GMI sensor is designed in the way of off-diagonal, its detectivity is extremely difficult to when using a probe
PT grades, the mode for generalling use space difference designs magnetic field gradient meter to realize the detection in pT grades of magnetic field, that is, uses two amorphous
Material separately designs two probes and is placed on different spatial positions, and uniform magnetic field (such as earth's magnetic field etc.) will be in such environment
Same impedance variation is generated in two probes.If two probes are placed on different spatial positions, one is placed on magnetic field sources to be measured
Near, two probe outputs are carried out difference synthesis and amplified, can thus arranged by another separate magnetic field sources to be measured
Except the interference in magnetic field uniform in environment, the signal of output corresponds only to magnetic source variation magnetic field and causes induced electromotive force, with this side
The detection in pT grades of magnetic field may be implemented in method, and schematic diagram of popping one's head in is as shown in Fig. 2, wherein Coil1 and Coil2 respectively indicates two probes
Induction coil,E coil1WithE coil2The induced electromotive force of induction coil output of two probes is respectively indicated (after being connected respectively to
Analog switch SH1 and the SH2 connection terminal of terminal circuit),LIt indicates between the induction coil of two probes apart from a certain distance,PE indicates that the signal of driving amorphous wire, G indicate ground connection.But above-mentioned magnetic field gradient meter is designed come real using space differential mode
Existing pT grades of detection of magnetic field, very high to the coherence request of probe, main is exactly to require two sections of amorphous wire electrical characteristic poles
It is consistent.Usual amorphous wire is difficult to accomplish good consistency, even if two sections of amorphous wire electrical characteristics of same batch in production
There may also be bigger difference, cause when doing differential probe design in this way, it is necessary to devote a tremendous amount of time selection two
The extremely close amorphous wire of section electrical characteristic, the induction electric that otherwise uniform magnetic field will generate in two probes will definitely be different
It causes, tens of thousands of times of such differential amplification whens can not only reduce the range of Magnetic Sensor, be easy to cause sensor output full when serious
With.Secondly in space parallax timesharing, two probe distances usually require to reach 3 centimetres or more, can just make pT grades of changes in this way
The induced electromotive force that the magnetic source of change generates in two probes has biggish difference, when sensor integration, volume
It is very big, be extremely unfavorable for the miniaturization of amorphous wire GMI Magnetic Sensor with it is integrated.
Summary of the invention
The technical problem to be solved in the present invention: in view of the above problems in the prior art, a kind of list based on GMI effect is provided
The inductive signal of single probe is become two-way mutually not through isolation separation by probe biological magnetic field detection method, circuit and sensor
The signal of interference carries out differential amplification after carrying out different low-pass filtering treatments respectively again, can be used for excluding in this way in environment
The interference in one magnetic field plays the preposition effect of High frequency filter, and can not consider amorphous wire material coherence request, is convenient for GMI
Sensor is miniaturized, is integrated.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention are as follows:
A kind of single probe biological magnetic field detection sensor based on GMI effect, including amorphous wire GMI probe, sharp pulse produce
Raw circuit, primary signal conditioning amplifying circuit, second signal conditioning amplifying circuit and three-level signal improve amplifying circuit, described first
Grade signal condition amplifying circuit is single probe biological magnetic field detection circuit based on GMI effect, and the amorphous wire GMI probe includes
Amorphous wire, induction coil, analog switch and detection capacitor, the output end phase of described amorphous wire one end and sharp pulse generation circuit
Even, other end ground connection, the induction coil are set around on amorphous wire, and the induction coil, analog switch, detection capacitor three are first
Tail is connected to form circuit, and the detectable signal that the detection capacitor is popped one's head in using one end close to analog switch as amorphous wire GMI is defeated
Outlet, the other end connecting pin as the reference voltage, the second signal conditioning amplifying circuit include notch filter and second level every
From amplifying circuit, the three-level signal conditioning amplifying circuit includes bandpass filter and three-level isolating amplifier circuit, single spy
The isolation circuit of first-born object detection of magnetic field circuit is connected with induction coil, the output end of single probe biological magnetic field detection circuit
It is sequentially connected with notch filter, second level isolating amplifier circuit, bandpass filter, three-level isolating amplifier circuit;It is described to be based on GMI
Single probe biological magnetic field detection circuit of effect include isolation circuit, the first low-pass filter unit, the second low-pass filter unit and
The input terminal of differential amplification unit, the isolation circuit is connected with the detectable signal output end that amorphous wire GMI pops one's head in, the isolation
The input terminal of one output end of circuit and the first low-pass filter unit is connected, another output and the second low-pass filter unit
Input terminal be connected, the input terminal of the differential amplification unit respectively with the first low-pass filter unit, the second low-pass filter unit
It is connected, the cutoff frequency of first low-pass filter unit is higher than the upper limit value for detecting target organism magnetic field signal frequency separation,
The cutoff frequency of second low-pass filter unit is lower than the lower limit value for detecting target organism magnetic field signal frequency separation.
The present invention is based on single probe biological magnetic field detection methods of GMI effect to have an advantage that
1, by analysis it is found that uniform magnetic field is mainly earth's magnetic field, when amorphous wire GMI probe orientation is fixed, these magnetic
Field will generate constant impedance variations in amorphous wire, and the output corresponding to induction coil will be stable DC part.It will be non-
The output signal isolation separation of brilliant silk GMI probe is independent two paths of signals, it is ensured that and two paths of signals is mutually indepedent and does not interfere with each other,
Then output signal all the way is subjected to the cutoff frequency low pass higher than the upper limit value for detecting target organism magnetic field signal frequency separation
Filtering, another output signal carry out the cutoff frequency low pass lower than the lower limit value for detecting target organism magnetic field signal frequency separation
It filters, so that including the stable DC part of environmental magnetic field in the signal after two-way is low-pass filtered, and all the way comprising biology
Detection of magnetic field signal, another way do not include biological magnetic field detectable signal, and signal of the two-way after low-pass filtered is carried out difference and is put
It, on the one hand can be by the stable DC partial offset of environmental magnetic field, thus the ring that is eliminated after obtaining biological magnetic field detectable signal greatly
On the other hand the biological magnetic field detectable signal in border magnetic field also functions to the preposition effect of High frequency filter, plays filtering environmental medium-high frequency
The effect of signal.
2, the present invention only needs single amorphous wire GMI probe can be realized, therefore the prior art can be overcome to use two
Magnetic field when difference of popping one's head near two probes may be in addition to uniform magnetic field there are also other magnetic interferences, therefore differential amplification
When without the concern for amorphous wire material coherence request, convenient for micromation, integrated, have the advantages that adaptivity is good.
The present invention is based on single probe biological magnetic field detection circuits of GMI effect, single probe biological magnetic field based on GMI effect
Detection sensor is the corresponding circuit of single probe biological magnetic field detection method or transducer arrangement configuration based on GMI effect,
Single probe biological magnetic field detection based on GMI effect can be realized by the structure of its circuit or sensor, therefore equally also have
There are the aforementioned advantages of single probe biological magnetic field detection method the present invention is based on GMI effect, therefore details are not described herein.
Detailed description of the invention
Fig. 1 is existing based on GMI effect biological magnetic field sensor probe schematic illustration.
Fig. 2 is prior art dual probe magnetic field gradient meter schematic illustration.
Fig. 3 is the basic procedure schematic diagram of present invention method.
Fig. 4 is the circuit theory schematic diagram of list of embodiment of the present invention probe biological magnetic field detection circuit.
Fig. 5 is the sensor structure schematic diagram using the embodiment of the present invention.
Marginal data: 1, isolation circuit;2, low-pass filter unit;3, the second low-pass filter unit;4, differential amplification unit;
5, amorphous wire GMI pops one's head in;51, amorphous wire;52, induction coil;53, analog switch;54, detection capacitor;6, sharp pulse generates electricity
Road;7, primary signal improves amplifying circuit;8, second signal improves amplifying circuit;81, notch filter;82, second level isolation is put
Big circuit;9, three-level signal improves amplifying circuit;91, bandpass filter;92, three-level isolating amplifier circuit.
Specific embodiment
As shown in figure 3, single probe biological magnetic field detection method step of the present embodiment based on GMI effect includes:
1) the output signal isolation of amorphous wire GMI probe detection signal output end is separated into independent and non-interfering two
Road signal;
2) the progress cutoff frequency of output signal all the way is higher than the upper limit value for detecting target organism magnetic field signal frequency separation
Low-pass filtering, another output signal carry out cutoff frequency than detect target organism magnetic field signal frequency separation lower limit value it is low
Low-pass filtering;
3) signal by two-way after low-pass filtered carries out differential amplification and obtains biological magnetic field detectable signal.
It should be noted that since different types of detection target organism magnetic field signal frequency is different, such as core field letter
Number, brain magnetic field signal, muscle magnetic field signal etc., therefore corresponding detection target organism magnetic field signal frequency separation is not yet
Together, in actual application, it can be determined according to the detection target organism magnetic field signal frequency separation that amorphous wire GMI pops one's head in
The cutoff frequency of two-way low-pass filtering output signal will carry out cutoff frequency than detection target organism magnetic field signal frequency zones all the way
Between the high low-pass filtering of upper limit value, another output signal carry out cutoff frequency than detection target organism magnetic field signal frequency zones
Between the low low-pass filtering of lower limit value.
It should be noted that different detection target organism magnetic field has different detection target organism magnetic field signal frequencies
Section.It is higher than the upper limit value for detecting target organism magnetic field signal frequency separation that cutoff frequency is carried out in the present embodiment, in step 2
Low-pass filtering when, DC component is not also filtered out and is retained at this time, and detecting target organism magnetic field signal also can be by
Retain;When carrying out lower limit value low low-pass filtering of the cutoff frequency than detecting target organism magnetic field signal frequency separation in step 2
DC component will be retained in probe signal in this way, and be detected target organism magnetic field signal and be then filtered out.By above-mentioned setting,
When two paths of signals difference, so that it may which the interference for excluding uniform magnetic field in environment guarantees that the biological magnetic field signal to be detected is protected
It stays.
In the present embodiment, the output signal isolation that amorphous wire GMI pops one's head in is separated into independence in step 1) and is not interfere with each other
Two paths of signals specifically refer to: toward amorphous wire GMI probe reference voltage connecting pin input reference voltage, amorphous wire GMI is visited
The voltage of the detectable signal output end output of head is exported respectively to the anode of two diodes, and the cathode of two diodes is distinguished
Output connector as independent and non-interfering two paths of signals.By the above-mentioned means, can simply, easily realize will be non-
The output signal isolation separation of brilliant silk GMI probe is independent two paths of signals, and while contributing to two paths of signals will not be mutual
Interference.It unquestionably, can also be using the isolation circuit including optocoupler, equally under conditions of not considering cost
It may be implemented the output signal isolation separation that amorphous wire GMI pops one's head in being independent two paths of signals, details are not described herein.
As shown in figure 4, single probe biological magnetic field detection circuit of the present embodiment based on GMI effect includes isolation circuit 1, the
One low-pass filter unit 2, the second low-pass filter unit 3 and differential amplification unit 4, the input terminal and amorphous wire GMI of isolation circuit 1
The detectable signal output end of probe is connected, an output end of isolation circuit 1 and the input terminal phase of the first low-pass filter unit 2
Even, another output is connected with the input terminal of the second low-pass filter unit 3, and the input terminal of differential amplification unit 4 is respectively with the
One low-pass filter unit 2, the second low-pass filter unit 3 are connected, and the cutoff frequency of the first low-pass filter unit 1 is more raw than detection target
The upper limit value of object magnetic field signal frequency separation is high, and the cutoff frequency of the second low-pass filter unit 2 is than detection target organism magnetic field letter
The lower limit value of number frequency separation is low.
As shown in figure 4, isolation circuit 1 includes diode conduction voltage drop balanced potentiometer RP, diode D1 and diode D2,
Diode conduction voltage drop balanced potentiometer RPA fixed termination power VCC, another fixing end ground connection or reference potential, tune
Section end is connected with the reference voltage connecting pin that amorphous wire GMI pops one's head in, and the anode of diode D1 and the anode of diode D2 connect jointly
It is connected to the detectable signal output end of amorphous wire GMI probe, the input terminal phase of the cathode of diode D1 and the first low-pass filter unit 2
Even, the input terminal of the cathode of diode D2 and the second low-pass filter unit 3 is connected.Diode conduction voltage drop balanced potentiometer RPWith
It improves reference voltage, offsets the conduction voltage drop of diode D1 and diode D2, so that diode is in pre- on state, even if
The induced electricity electromotive force for obtaining amorphous wire GMI probe can be passed in subsequent conditioning circuit by diode D1 and diode D2.It considers
The conduction voltage drop about 0.1V of diode D1 and diode D20.7V, amorphous wire GMI probe, therefore in the present embodiment, diode is led
Logical pressure drop balanced potentiometer RPAdjustable side output voltage be greater than 0.8V, so as to ensure offset diode D1 and diode D2
Conduction voltage drop so that diode is in pre- on state.
As shown in figure 4, the first low-pass filter unit 2 includes capacitor C1, resistance R1 and resistance R2, resistance R2 is serially connected with two poles
Between the cathode of pipe D1, an input terminal of differential amplification unit 4, one end of resistance R1 is connected to the cathode of diode D1, electricity
It hinders between R2, the other end ground connection of resistance R1 or reference potential, one end of capacitor C1 are connected to resistance R2, differential amplification unit 4
An input terminal between, the other end of capacitor C1 ground connection or reference potential.The effect of low-pass filter is exactly to be believed by low frequency
Number, filter out high-frequency signal, capacitor C1, resistance R1 and resistance R2 form the passive low ventilating filter, -3dB of passive low ventilating filter
Cutoff frequency f01Meet formula f01=1/(2πR2C1), wherein R2For the resistance value of resistance R2, C1For the capacitance of capacitor C1.
As shown in figure 4, the second low-pass filter unit 3 includes capacitor C2, resistance R3 and resistance R4, resistance R4 is serially connected with two poles
Between the cathode of pipe D2, another input terminal of differential amplification unit 4, one end of resistance R3 be connected to diode D2 cathode,
Between resistance R4, the other end ground connection of resistance R3 or reference potential, one end of capacitor C2 are connected to resistance R4, differential amplification unit
Between 4 another input terminal, the other end ground connection of capacitor C2 or reference potential.Second low-pass filter circuit 3 and the first low pass
2 structure of filter circuit is identical, and only cutoff frequency is different, in the present embodiment, the cutoff frequency f of the second low-pass filter circuit 302It is full
Sufficient formula f02=1/(2πR3C2), wherein R3For the resistance value of resistance R3, C2For the capacitance of capacitor C2.R1=R3 in the present embodiment,
In view of the resistance value that the conducting resistance of diode D1 and D2 are 400 ~ 600 Ω, R1 and R3 is greater than 6k Ω.
As shown in figure 4, differential amplification unit 4 includes that differential amplification module and amplification factor adjust resistance RG, differential amplification
Module includes the output end that two groups of input terminals and one are used to export biological magnetic field detectable signal, and each group of input terminal includes two
Connection terminal, a connection terminal of first group of input terminal and the output end of the first low-pass filter unit 2 are connected, second group of input
One connection terminal at end and the output end of the second low-pass filter unit 3 are connected, another terminal of first group of input terminal passes through
Amplification factor adjusts resistance RG and is directly connected with another connection terminal of second group of input terminal.In the present embodiment, differential amplification
Module specifically uses instrument amplifier to realize, operation furthermore can also be used using other differential amplification operation chips or voluntarily
Amplifier builds realization.
The present embodiment both can individually have been sold based on single probe biological magnetic field detection circuit of GMI effect, in addition it is also possible to
The present embodiment is directly integrated into single probe biological magnetic field detection sensing based on single probe biological magnetic field detection circuit of GMI effect
In device.
As shown in figure 5, being integrated with single probe life of single probe biological magnetic field detection circuit of the present embodiment based on GMI effect
Object detection of magnetic field sensor includes amorphous wire GMI probe 5, sharp pulse generation circuit 6, primary signal conditioning amplifying circuit 7, second level
Signal condition amplifying circuit 8 and three-level signal improve amplifying circuit 9, and it is that the present embodiment is aforementioned that primary signal, which improves amplifying circuit 7,
Single probe biological magnetic field detection circuit based on GMI effect, amorphous wire GMI probe 5 includes amorphous wire 51, induction coil 52, mould
Quasi- switch 53 and capacitor 54,51 one end of amorphous wire is connected with the output end of sharp pulse generation circuit 6, the other end is grounded, the line of induction
Circle 52 is set around on amorphous wire 51, and induction coil 52, analog switch 53,54 three of capacitor join end to end forming circuit, and detection is electric
Holding 54, the detectable signal output end of probe 5, the other end are electric as reference using one end close to analog switch 53 as amorphous wire GMI
Connecting pin is pressed, it includes notch filter 81(50Hz that second signal, which improves amplifying circuit 8) and second level isolating amplifier circuit 82, three-level
Signal condition amplifying circuit 9 includes bandpass filter 91 and three-level isolating amplifier circuit 92, single biological magnetic field detection circuit of popping one's head in
Isolation circuit 1 be connected with induction coil 52, the output end and notch filter 81, second level of single biological magnetic field detection circuit of popping one's head in
Isolating amplifier circuit 82, bandpass filter 91, three-level isolating amplifier circuit 92 are sequentially connected.Due to amorphous wire GMI probe 5 it is defeated
Signal is very weak out, it is therefore desirable to improve amplifying circuit 7 by primary signal, second signal improves amplifying circuit 8 and three-level signal
Conditioning amplifying circuit 9 is amplified step by step, to finally obtain the amplification of 100,000 times of ranks or so, wherein notch filter 81 is used
In the influence for excluding Hz noise in environment, bandpass filter 91 is used for the effect of exclusive PCR, so that it is guaranteed that amplified signal
Accuracy.
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-mentioned implementation
Example, all technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art
Those of ordinary skill for, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications
It should be regarded as protection scope of the present invention.
Claims (1)
1. a kind of single probe biological magnetic field detection sensor based on GMI effect, including amorphous wire GMI probe (5), sharp pulse produce
Raw circuit (6), primary signal conditioning amplifying circuit (7), second signal conditioning amplifying circuit (8) and three-level signal conditioning amplification electricity
Road (9), it is characterised in that: primary signal conditioning amplifying circuit (7) is single probe biological magnetic field detection based on GMI effect
Circuit, the amorphous wire GMI probe (5) includes amorphous wire (51), induction coil (52), analog switch (53) and detection capacitor
(54), described amorphous wire (51) one end is connected with the output end of sharp pulse generation circuit (6), the other end is grounded, the line of induction
Circle (52) is set around on amorphous wire (51), the induction coil (52), analog switch (53), detection capacitor (54) three's head and the tail phase
It is even formed into a loop, the detection of the detection capacitor (54) probe (5) using one end close to analog switch (53) as amorphous wire GMI
Signal output end, the other end connecting pin as the reference voltage, second signal conditioning amplifying circuit (8) includes notch filter
(81) and second level isolating amplifier circuit (82), three-level signal conditioning amplifying circuit (9) includes bandpass filter (91) and three
The isolation circuit (1) of grade isolating amplifier circuit (92), single probe biological magnetic field detection circuit is connected with induction coil (52),
The output end and notch filter (81), second level isolating amplifier circuit (82), band logical of single probe biological magnetic field detection circuit
Filter (91), three-level isolating amplifier circuit (92) are sequentially connected;Single probe biological magnetic field detection electricity based on GMI effect
Road includes isolation circuit (1), the first low-pass filter unit (2), the second low-pass filter unit (3) and differential amplification unit (4), institute
It states the input terminal of isolation circuit (1) and detectable signal output end that amorphous wire GMI pops one's head in is connected, the one of the isolation circuit (1)
The input terminal of a output end and the first low-pass filter unit (2) is connected, another output and the second low-pass filter unit (3)
Input terminal be connected, the input terminal of the differential amplification unit (4) respectively with the first low-pass filter unit (2), the second low-pass filtering
Unit (3) is connected, and the cutoff frequency of first low-pass filter unit (1) is than detection target organism magnetic field signal frequency separation
Upper limit value is high, and the cutoff frequency of second low-pass filter unit (2) is than under detection target organism magnetic field signal frequency separation
Limit value is low.
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CN112729247B (en) * | 2020-12-15 | 2022-09-30 | 李艳 | Ground-air complementary remote sensing measurement method based on computer communication |
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