CN106483047A - A kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer - Google Patents

A kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer Download PDF

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Publication number
CN106483047A
CN106483047A CN201510528698.9A CN201510528698A CN106483047A CN 106483047 A CN106483047 A CN 106483047A CN 201510528698 A CN201510528698 A CN 201510528698A CN 106483047 A CN106483047 A CN 106483047A
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China
Prior art keywords
freezing solution
freezing
solution case
osmotic pressure
case
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CN201510528698.9A
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陈鹤
周小玲
陈良钜
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SHANGHAI YIDA MEDICAL INSTRUMENT CO Ltd
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SHANGHAI YIDA MEDICAL INSTRUMENT CO Ltd
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Abstract

The present invention discloses a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer, and it includes main non-freezing solution case, the heat-insulation layer being arranged on around main non-freezing solution case, semiconductor chilling plate and fin;It is provided with measured test tube, test tube bracket, the spring below test tube bracket in main non-freezing solution case, main non-freezing solution case side is provided with secondary non-freezing solution case, it is provided with the chilled tubes equipped with sample in secondary non-freezing solution case, secondary non-freezing solution upper box part is provided with heat-insulated upper lid, cover on heat-insulated and be additionally provided with chilled tubes lift lug, be provided with the chilled tubes bracket supporting chilled tubes in the lower section of chilled tubes lift lug;Secondary non-freezing solution case is connected with described main non-freezing solution case.By adding secondary non-freezing solution case in main non-freezing solution case side, sample is carried out with pre-cooling cooling, and then realizes the fast cooling detection to sample, shorten sample detection time.Meanwhile, also add liquid level detection device, visual interpolation non-freezing solution can be realized on liquid crystal display screen with the liquid level of real-time detection non-freezing solution.

Description

A kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer
Technical field
The invention belongs to the automatization of the freezing point osmotic pressure analyzer in medical apparatus and instruments improves device, more particularly, to a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer.
Background technology
Various biological fluids typically each can be considered the solution forming with water as solvent with the various electrolyte closely related with organism metabolism and non-electrolyte, though the material composition of intraor extracellular is not quite similar, but the osmotic pressure of intraor extracellular is but identical, and the certain osmotic pressure of body fluid maintenance is to constitute one of metastable essential condition of organismic internal environment.
Osmometry applies the pharmacology analysis in Chinese herbal medicine, the development of medicine and different kind organism reagent, production, monitoring, and osmotic pressure molar density algoscopy is included newly-increased regulation detection method by state-promulgated pharmacopoeia.
Crystal freezing point osmotic tester principle is based on the molar concentration direct proportionality of freeze point depression and solution.Freezing point osmotic pressure analyzer is widely used to the detection of the liquid such as the blood of hospital clinical, urine, dialysis solution, histiocyte culture fluid, osmotic pressure index is becoming pregnant, gestation, artificial fertilization are increasingly taken seriously, and applies in section office such as kidney, nerve, endocrine, burn, ICU, infertility.
Freezing point osmotic pressure analyzer is typically made up of refrigerating plant, disturbance device, temperature transducer and computer system and display apparatus.Disturbance device can be divided into stirring structure form and two kinds of forms of vibrational structure form at present, stirring structure is typically in the form of a stainless pin in the form of moving up and down, and the once or several times moment insertion when detected solution temperature reaches apparent freezing point forms violent disturbance.Vibrational structure is typically in the form of a steel push rod in the form of side-to-side movement, and the once or several times moment impact when detected solution temperature reaches apparent freezing point takes up the sample cell of detected solution and forms violent disturbance.
Only one non-freezing solution casing being used for refrigeration of freezing point osmotic pressure analyzer of the prior art.There is shortcoming in existing equipment:
1st, using monocyte sample detection, sample drops to the zubzero temperature of detection from room temperature to instrument custom, it usually needs about 100 seconds cool time, therefore work efficiency is relatively low.
2nd, the non-freezing solution casing top of existing instrument has sample holes, often in -9 DEG C of working environment, surrounding is required to be provided with thermal-insulating sealing, the number of non-freezing solution in casing cannot intuitively be understood, take part non-freezing solution out of in the evaporation of non-freezing solution and each detection process in use and reduce, therefore cannot know and accurately be aware of when that this adds non-freezing solution into casing, and the non-freezing solution of this interpolation quantity.
Content of the invention
In order to solve the above-mentioned problems in the prior art, it is an object of the invention to provide a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer.By adding secondary non-freezing solution case in main non-freezing solution case side, treat the sample in testing tube and carry out pre-cooling, realize for the sample under room temperature state being reduced to 0 DEG C about, then when test, it is reduced to detection temperature by 0 DEG C(Generally -6 DEG C about);And then realize quick detection, shorten sample detection time.Meanwhile, also add liquid level detection device, can realize visual attaching non-freezing solution with the liquid level of real-time detection non-freezing solution.
To achieve these goals, the technical solution used in the present invention is:A kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer, including main non-freezing solution case, the heat-insulation layer of the surrounding being arranged on main non-freezing solution case, semiconductor chilling plate and fin;It is provided with measurement test tube, the test tube bracket supporting measurement test tube, the spring below test tube bracket in described main non-freezing solution case, it is additionally provided with secondary non-freezing solution case in main non-freezing solution case side, it is provided with the chilled tubes equipped with sample in described pair non-freezing solution case, secondary non-freezing solution upper box part is provided with heat-insulated upper lid, described heat-insulated on cover and be additionally provided with chilled tubes lift lug, be provided with the chilled tubes bracket supporting chilled tubes in the lower section of chilled tubes;Described pair non-freezing solution case is connected with described main non-freezing solution case.
Preferably technical scheme, is additionally provided with liquid level detection device in described pair non-freezing solution case.Increased liquid level detection device, can realize that enclosed environment is visual to attach non-freezing solution with the liquid level of real-time detection non-freezing solution.
Described liquid level detection device includes each of three electrodes detecting head, and wherein one is the upper liquid level detecting head of non-freezing solution, and another two is the lower level detection head of non-freezing solution.
The length of described two lower level detection heads and investigation depth are equal.
Described liquid level detection device also includes LCDs, and described each of three electrodes detecting head is all connected by control circuit and connects with the real-time height showing liquid level with LCDs.The liquid level of the non-freezing solution in equipment can be visualized by LCDs, when needing to add non-freezing solution, appropriate non-freezing solution can be added to non-freezing solution casing in time, it is to avoid because the accuracy of detection of non-freezing solution not enough impact sample and time.
Preferably technical scheme, the 3/5 of the depth of non-freezing solution case based on the depth of described pair non-freezing solution case.Make 3/5 depth of non-freezing solution case based on the depth of secondary non-freezing solution case, with the proportionate relationship of the non-freezing solution amount between effective control pair non-freezing solution case and main non-freezing solution case, and then the temperature relation between secondary non-freezing solution case and main non-freezing solution case can be controlled.Accurately accomplish when the temperature of main non-freezing solution case is at -9 DEG C about, the temperature of secondary non-freezing solution case is at -6 DEG C about.
Preferably technical scheme, is provided with dividing plate between described pair non-freezing solution case and main non-freezing solution case, has the intercommunicating pore of the secondary non-freezing solution case of connection and main non-freezing solution case in described the lower partition.Upper spacer will be set between master/slave non-freezing solution case, then open up intercommunicating pore so that constituting the structure of approximate linker between secondary non-freezing solution case and main non-freezing solution case in the lower partition.So that the non-freezing solution between them can be circulated, and then realize the temperature difference relation between secondary non-freezing solution case and main non-freezing solution case.
It is additionally provided with temperature probe in described main non-freezing solution case.
Using above technical scheme, the non-freezing solution box assembly of the freezing point osmotic pressure analyzer of the present invention solves existing non-freezing solution casing cooling sample time length, work efficiency is low, the problems such as be unable to the height of liquid level of non-freezing solution in monitor in real time casing.
The non-freezing solution box assembly of the present invention, compared with existing non-freezing solution case, has advantages below:
1., because cooling piece is close to non-freezing solution main box so as to quickly cold can be supplemented, stablize at -9 DEG C, and auxiliary box body be at -6 DEG C.
2. auxiliary box body can allow sample in test tube from room temperature(30℃)It is quickly reduced to and closes on 0 DEG C of operating temperature of detection, allow the sample direct detection time shorten about 30%;
3. directly perceived understand enclosed environment in casing in non-freezing solution number, when reaching upper liquid level when liquid feeding, liquid crystal display screen is pointed out immediately, can stop liquid feeding.
4. when non-freezing solution gradually decreases and reaches lower liquid level, liquid feeding can be pointed out on liquid crystal display screen, to guarantee the accuracy of test data and to accelerate detection time.
Brief description
Fig. 1 is the main view cross section structure diagram of the non-freezing solution box assembly of freezing point osmotic pressure analyzer of the present invention.
Fig. 2 is the overlooking the structure diagram of the non-freezing solution box assembly of freezing point osmotic pressure analyzer of the present invention;
Fig. 3 is the partial structural diagram of the liquid level detection device of non-freezing solution box assembly of freezing point osmotic pressure analyzer of the present invention.
Specific embodiment
For making the object, technical solutions and advantages of the present invention of greater clarity, with reference to instantiation, the present invention is described in more detail.It should be understood that these descriptions are simply exemplary, and it is not intended to limit the scope of the present invention.Additionally, in the following description, eliminate the description to known features and technology, to avoid unnecessarily obscuring idea of the invention.
Embodiment 1:
As shown in Figure 1 to Figure 3, a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer, including main non-freezing solution case 05, the heat-insulation layer 17 of the surrounding being arranged on main non-freezing solution case 05, semiconductor chilling plate 16 and fin 15;It is provided with measurement test tube 06 in described main non-freezing solution case 05, support the test tube bracket 07 of measurement test tube 06, be located at the spring 08 of test tube bracket 07 lower section, it is additionally provided with secondary non-freezing solution case 04 in main non-freezing solution case 05 side, it is provided with chilled tubes 03 in described pair non-freezing solution case 04, secondary non-freezing solution case 04 top is provided with heat-insulated upper lid 02, it is additionally provided with chilled tubes lift lug 01 on described heat-insulated upper lid 02, be provided with the chilled tubes bracket 09 supporting chilled tubes 03 in the lower section of chilled tubes 03;Described pair non-freezing solution case 04 is connected with described main non-freezing solution case 05.
It is additionally provided with liquid level detection device 18 in described pair non-freezing solution case 04.Increased liquid level detection device 18, can realize that enclosed environment is visual to attach non-freezing solution with the liquid level of real-time detection non-freezing solution.
Described liquid level detection device 18 includes each of three electrodes detecting head 12,13, and wherein one is the upper liquid level detecting head 12 of non-freezing solution, and another two is the lower level detection 13 of non-freezing solution.
The length of described two lower level detection 13 and investigation depth are equal.
Described liquid level detection device 18 also includes LCDs(In figure is not drawn into), described each of three electrodes detecting head 12,13 is all connected by control circuit and connects with the real-time height showing liquid level with LCDs.The liquid level of the non-freezing solution of equipment inner sealing environment can be visualized by LCDs, when needing to add non-freezing solution, appropriate non-freezing solution can be added to non-freezing solution casing in time, it is to avoid because the accuracy of detection of non-freezing solution not enough impact sample and time.
The 3/5 of the depth of non-freezing solution case 05 based on the depth of described pair non-freezing solution case 04.Make 3/5 depth of non-freezing solution case 05 based on the depth of secondary non-freezing solution case 04, with the proportionate relationship of the non-freezing solution amount between effective control pair non-freezing solution case 04 and main non-freezing solution case 05, and then the temperature relation between secondary non-freezing solution case 04 and main non-freezing solution case 05 can be controlled.Accurately accomplish when the temperature of main non-freezing solution case 05 is at -9 DEG C about, the temperature of secondary non-freezing solution case 04 is at -6 DEG C about.
It is provided with dividing plate 10 between described pair non-freezing solution case 04 and main non-freezing solution case 05, have the intercommunicating pore 11 of the secondary non-freezing solution case 04 of connection and main non-freezing solution case 05 in described dividing plate 10 bottom.Upper spacer 10 will be set between master/slave non-freezing solution case 05,04, then open up intercommunicating pore 11 so that constituting the structure of approximate linker between secondary non-freezing solution case 04 and main non-freezing solution case 05 in dividing plate 10 bottom.So that the non-freezing solution between them can be circulated, and then the temperature relation realized between secondary non-freezing solution case 04 and main non-freezing solution case 05 is controlled.It is additionally provided with temperature probe 14 in described main non-freezing solution case 05.
It should be appreciated that the principle that the above-mentioned specific embodiment of the present invention is used only for exemplary illustration or explains the present invention, and be not construed as limiting the invention.Therefore, any modification, equivalent substitution and improvement done in the case of the thought without departing from the present invention and scope etc., should be included within the scope of the present invention.Additionally, claims of the present invention whole changing and modifications of being intended to fall in scope and border or the equivalents on this scope and border.

Claims (8)

1. a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer, including main non-freezing solution case, the heat-insulation layer of the surrounding being arranged on main non-freezing solution case, semiconductor chilling plate and fin;Be provided with described main non-freezing solution case measured test tube, support measure test tube test tube bracket, be located at test tube bracket below spring it is characterised in that:It also includes being arranged on the secondary non-freezing solution case of main non-freezing solution case side, it is provided with the chilled tubes equipped with sample in described pair non-freezing solution case, secondary non-freezing solution upper box part is provided with heat-insulated upper lid, described heat-insulated on cover and be additionally provided with chilled tubes lift lug, be provided with the chilled tubes bracket supporting chilled tubes in the lower section of chilled tubes lift lug;Described pair non-freezing solution case is connected with described main non-freezing solution case.
2. according to claim 1 a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer it is characterised in that:It is additionally provided with liquid level detection device in described pair non-freezing solution case.
3. according to claim 2 a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer it is characterised in that:Described liquid level detection device includes each of three electrodes detecting head, and wherein one is the upper liquid level detecting head of non-freezing solution, and another two is the lower level detection head of non-freezing solution.
4. according to claim 3 a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer it is characterised in that:The length of described two lower level detection heads and investigation depth are equal.
5. according to claim 3 a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer it is characterised in that:Described liquid level detection device also includes LCDs, after described each of three electrodes detecting head is all connected by control circuit, then connects with LCDs, with the real-time height showing liquid level.
6. according to claim 1 a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer it is characterised in that:The 3/5 of the depth of non-freezing solution case based on the depth of described pair non-freezing solution case.
7. according to claim 1 a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer it is characterised in that:It is provided with dividing plate between described pair non-freezing solution case and main non-freezing solution case, have the intercommunicating pore of the secondary non-freezing solution case of connection and main non-freezing solution case in described the lower partition.
8. according to claim 1 a kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer it is characterised in that:It is additionally provided with temperature probe in described main non-freezing solution case.
CN201510528698.9A 2015-08-26 2015-08-26 A kind of non-freezing solution box assembly of freezing point osmotic pressure analyzer Pending CN106483047A (en)

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Application publication date: 20170308