CN106478776A - 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 - Google Patents
抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 Download PDFInfo
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Classifications
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
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Landscapes
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Applications Claiming Priority (5)
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| US201161509340P | 2011-07-19 | 2011-07-19 | |
| US61/509340 | 2011-07-19 | ||
| US201261662337P | 2012-06-20 | 2012-06-20 | |
| US61/662337 | 2012-06-20 | ||
| CN201280045650.7A CN103890003B (zh) | 2011-07-19 | 2012-07-19 | 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201280045650.7A Division CN103890003B (zh) | 2011-07-19 | 2012-07-19 | 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 |
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| CN106478776A true CN106478776A (zh) | 2017-03-08 |
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| CN201610543024.0A Pending CN106478776A (zh) | 2011-07-19 | 2012-07-19 | 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 |
| CN201280045650.7A Expired - Fee Related CN103890003B (zh) | 2011-07-19 | 2012-07-19 | 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201280045650.7A Expired - Fee Related CN103890003B (zh) | 2011-07-19 | 2012-07-19 | 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 |
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| Country | Link |
|---|---|
| US (2) | US20140057831A1 (enExample) |
| EP (1) | EP2734220A4 (enExample) |
| JP (1) | JP2014527040A (enExample) |
| CN (2) | CN106478776A (enExample) |
| AU (1) | AU2012283924A1 (enExample) |
| BR (1) | BR112014001268A2 (enExample) |
| CA (1) | CA2842330A1 (enExample) |
| HK (1) | HK1198333A1 (enExample) |
| IL (1) | IL230510A0 (enExample) |
| RU (1) | RU2014105513A (enExample) |
| WO (1) | WO2013013085A2 (enExample) |
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| WO2016054155A1 (en) * | 2014-09-30 | 2016-04-07 | Primegen Biotech, Llc. | Treatment of fibrosis using deep tissue heating and stem cell therapy |
| US20160137714A1 (en) * | 2014-11-12 | 2016-05-19 | Thrasos Innovation, Inc. | Peptides with enhanced stability and their use in methods for treating diseases |
| EP3289073A4 (en) | 2015-05-01 | 2019-07-17 | University of Miami | METHOD AND COMPOSITIONS FOR THE CONVERSION OF NON-ENDOCRINE PANCREATIC TISSUE IN INSULIN-PRODUCING CELLS |
| US10434134B2 (en) * | 2015-05-12 | 2019-10-08 | The Regents Of The University Of California | Peptide treatment for inflammation and fibrosis |
| EP3303383A1 (en) * | 2015-06-05 | 2018-04-11 | iBio, Inc. | Endostatin fragments and variants for use in treating fibrosis |
| WO2019133950A1 (en) * | 2017-12-30 | 2019-07-04 | The Regents Of The University Of Colorado, A Body Corporate | Smad7 for treatment and prevention of posterior capsule opacification |
| ES2906715T3 (es) * | 2018-09-06 | 2022-04-20 | Marine Essence Biosciences Corp Of Usa | Dispositivos de biomaterial para la regeneración de tejidos guiada |
| CA3117323A1 (en) * | 2018-10-22 | 2020-04-30 | William D. Carlson | Therapeutic combinations of tdfrps and additional agents and methods of use |
| US20210008173A1 (en) * | 2019-07-10 | 2021-01-14 | Musc Foundation For Research Development | Endostatin peptides for the treatment of tumors, fibrosis and acute lung injury |
| CN117106029A (zh) * | 2020-06-08 | 2023-11-24 | 深圳市图微安创科技开发有限公司 | 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途 |
| CA3212468A1 (en) * | 2021-03-16 | 2022-09-22 | William D. Carlson | Therapeutic combinations of tdfrps and additional agents and methods of use for the reversal of fibrosis |
| CN113069531B (zh) * | 2021-04-09 | 2023-02-28 | 南开大学 | 一种防疤痕皮肤创伤修复用水凝胶及其制备方法 |
| CN116768974A (zh) * | 2022-03-11 | 2023-09-19 | 中山大学 | 用于预防和/或治疗肾纤维化的多肽化合物 |
| EP4601667A1 (en) | 2022-10-10 | 2025-08-20 | Therapeutics by Design, LLC | Tissue differentiation factor related polypeptides (tdfrps) for the treatment of myocardial injury |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1219133A (zh) * | 1996-03-22 | 1999-06-09 | 通用医疗公司 | 中枢神经系统局部缺血或损伤后多肽生长因子的给药 |
| WO2007035872A2 (en) * | 2005-09-20 | 2007-03-29 | Thrasos Therapeutics, Inc. | Tdf-related compounds and analogs thereof |
| US20100015150A1 (en) * | 2004-06-17 | 2010-01-21 | Thrasos Therapeutics, Inc. | Tdf-related compounds and analogs thereof |
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| EP2392659B1 (en) * | 2002-06-17 | 2015-01-14 | Thrasos Innovation, Inc. | Single domain TDF-related compounds and analogs thereof |
| CN102405287A (zh) * | 2009-01-16 | 2012-04-04 | 新加坡科技研究局 | 抑制肝星状细胞增殖的方法 |
| EP2401614A1 (en) * | 2009-02-27 | 2012-01-04 | OSI Pharmaceuticals, LLC | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
| EP2427494B1 (en) * | 2009-05-08 | 2017-10-18 | Novartis AG | Methods of modulating fibrosis using bone morphogenetic protein-9 (bmp-9) modulators |
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- 2012-07-19 RU RU2014105513/04A patent/RU2014105513A/ru not_active Application Discontinuation
- 2012-07-19 BR BR112014001268A patent/BR112014001268A2/pt not_active IP Right Cessation
- 2012-07-19 US US13/553,685 patent/US20140057831A1/en not_active Abandoned
- 2012-07-19 CA CA2842330A patent/CA2842330A1/en not_active Abandoned
- 2012-07-19 HK HK14111848.5A patent/HK1198333A1/zh unknown
- 2012-07-19 EP EP12814119.9A patent/EP2734220A4/en not_active Withdrawn
-
2014
- 2014-01-16 IL IL230510A patent/IL230510A0/en unknown
-
2015
- 2015-08-05 US US14/818,652 patent/US20160058829A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1219133A (zh) * | 1996-03-22 | 1999-06-09 | 通用医疗公司 | 中枢神经系统局部缺血或损伤后多肽生长因子的给药 |
| US20100015150A1 (en) * | 2004-06-17 | 2010-01-21 | Thrasos Therapeutics, Inc. | Tdf-related compounds and analogs thereof |
| WO2007035872A2 (en) * | 2005-09-20 | 2007-03-29 | Thrasos Therapeutics, Inc. | Tdf-related compounds and analogs thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014105513A (ru) | 2015-08-27 |
| EP2734220A2 (en) | 2014-05-28 |
| US20160058829A1 (en) | 2016-03-03 |
| WO2013013085A2 (en) | 2013-01-24 |
| CN103890003B (zh) | 2016-08-24 |
| CN103890003A (zh) | 2014-06-25 |
| US20140057831A1 (en) | 2014-02-27 |
| HK1198333A1 (zh) | 2015-04-02 |
| JP2014527040A (ja) | 2014-10-09 |
| EP2734220A4 (en) | 2015-01-21 |
| CA2842330A1 (en) | 2013-01-24 |
| WO2013013085A3 (en) | 2014-03-13 |
| BR112014001268A2 (pt) | 2017-02-21 |
| IL230510A0 (en) | 2014-03-31 |
| AU2012283924A1 (en) | 2014-02-06 |
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