CN106472560A - 一种氧气湿化液抑菌剂 - Google Patents

一种氧气湿化液抑菌剂 Download PDF

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CN106472560A
CN106472560A CN201610813504.4A CN201610813504A CN106472560A CN 106472560 A CN106472560 A CN 106472560A CN 201610813504 A CN201610813504 A CN 201610813504A CN 106472560 A CN106472560 A CN 106472560A
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bacteriostatic agent
humidifying liquid
oxygen
hydrogen peroxide
oxygen humidifying
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吴百乐
吴非逸
徐亚昌
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Zhejiang University ZJU
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Zhejiang University ZJU
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/06—Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/10—Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

本发明公开了一种氧气湿化液抑菌剂，本发明的主要成分是低浓度的过氧化氢水溶液，并添加了少量调节剂。其中，每1000mL蒸馏水或去离子水中过氧化氢含量为0.01～2.0g，调节剂为苯甲酸、山梨酸、乙酸、甲酸、甘氨酸或柠檬中的一种，调节剂的含量是每1000mL湿化液抑菌剂中含0.1‑10g。本氧气湿化液抑菌剂能够有效抑制细菌的繁殖，保证湿化液不被感染，从而避免交叉感染的发生，进入人体后无毒副作用，并可进一步提高病人吸氧的舒适度和护理人员的工作效率。

Description

一种氧气湿化液抑菌剂
技术领域
本发明涉及医疗用品技术领域，尤其涉及一种氧气湿化液抑菌剂。
背景技术
氧疗是临床最常用的护理技术及抢救治疗手段。氧气湿化液的使用可避免干燥的氧气对呼吸道黏膜的刺激，提高氧疗效果和患者的舒适度。目前临床上仍广泛使用蒸馏水作为氧气湿化液，但由于蒸馏水本身不具备消毒、抑菌作用，在潮湿温暖环境中又极易使细菌生长繁殖，所以不是一种理想的氧气湿化液。
发明内容
本发明目的是克服上述背景技术的不足，提供一种氧气湿化液抑菌剂，该抑菌剂应能有效代替蒸馏水用作氧气湿化液，具有抑菌效果好，安全性高，进入人体后无毒副作用的特点。
本发明提供的技术方案是：一种氧气湿化液抑菌剂，它包含过氧化氢和水，所述过氧化氢和水的质量体积比(g/mL)为0.01～2.0:1000；所述水为蒸馏水或去离子水。
进一步地，每1000mL湿化液抑菌剂还包括0.1-10g的苯甲酸、山梨酸、乙酸、甲酸、甘氨酸或柠檬酸。苯甲酸、山梨酸、乙酸、甲酸、甘氨酸、柠檬酸作为调节剂，其作用是增加过氧化氢稳定性、增强抑菌和杀菌能力、调节抑菌剂的pH值。
本发明的有益效果是：过氧化氢水溶液俗称双氧水，医用双氧水可杀灭肠道致病菌、化脓性球菌，致病酵母菌，一般用于物体表面消毒。过氧化氢分解为水和氧分子(初生态氧)，从而将微生物的酶系统氧化，从而达到抑菌目的，抑菌效果好，安全性高，进入人体后无毒副作用。浓度大于3％的双氧水虽抑菌效果强，但对呼吸系统有刺激，不宜作为吸氧湿化液。本发明的氧气湿化液抑菌剂中的过氧化氢的含量浓度极低(仅为0.001～0.2％)，对呼吸系统无刺激作用。用氧气湿化液抑菌剂代替蒸馏水作氧气湿化液，可以预防吸氧湿化液在瓶中细菌、微生物滋生，极大地降低因吸氧引起院内感染的风险，杜绝吸氧有关的交叉感染；可广泛应用于临床上吸氧治疗、呼吸机治疗、新生儿暖箱以及气道润湿等，并能进一步提高病人吸氧的舒适度和护理人员的工作效率。此外，本发明制备工艺简单，成本低廉，具有普遍推广使用的社会意义。
具体实施方式
本发明可用下面实施例加以说明。
实施例1：
在容器中加入1.0mL30％医用双氧水和一定量的去离子水，再加入1.0g苯甲酸，最后加入去离子水定容至1000mL，得到可直接使用的氧气湿化液抑菌剂。
检验合格后分装入湿化瓶中供临床使用。
实施例2：
在容器中加入0.5mL30％医用双氧水和一定量的去离子水，再加入1.0g苯甲酸，最后加入去离子水定容至1000mL，得到可直接使用的氧气湿化液抑菌剂。
检验合格后分装入湿化瓶中供临床使用。
实施例3：
在容器中加入1.0mL30％医用双氧水和一定量的去离子水，再加入1.0g山梨酸，最后加入去离子水定容至1000mL，得到可直接使用的氧气湿化液抑菌剂。
检验合格后分装入湿化瓶中供临床使用。
实施例4：
在容器中加入1.0mL30％医用双氧水和一定量的去离子水，再加入1.0g甲酸，最后加入去离子水定容至1000mL，得到可直接使用的氧气湿化液抑菌剂。
检验合格后分装入湿化瓶中供临床使用。
实施例5：
在容器中加入1.0mL30％医用双氧水和一定量的去离子水，再加入1.0g乙酸，最后加入去离子水定容至1000mL，得到可直接使用的氧气湿化液抑菌剂。
检验合格后分装入湿化瓶中供临床使用。
实施例6：
在容器中加入1.0mL30％医用双氧水和一定量的去离子水，再加入1.0g甘氨酸，最后加入去离子水定容至1000mL，得到可直接使用的氧气湿化液抑菌剂。
检验合格后分装入湿化瓶中供临床使用。
实施例7：
在容器中加入1.0mL30％医用双氧水和一定量的去离子水，再加入1.0g柠檬酸，最后加入去离子水定容至1000mL，得到可直接使用的氧气湿化液抑菌剂。
检验合格后分装入湿化瓶中供临床使用。

Claims (2)

1.一种氧气湿化液抑菌剂，其特征在于，它包含过氧化氢和水，所述过氧化氢和水的质量体积比(g/mL)约为0.01～2.0:1000；所述水为蒸馏水或去离子水。
2.根据权利要求1所述的氧气湿化液抑菌剂，其特征在于：每1000mL湿化液抑菌剂还包括0.1-10g的苯甲酸、山梨酸、乙酸、甲酸、甘氨酸或柠檬酸。
CN201610813504.4A 2016-09-11 2016-09-11 一种氧气湿化液抑菌剂 Pending CN106472560A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111838176A (zh) * 2020-08-05 2020-10-30 江苏中新瑞光学材料有限公司 一种氧气湿化液抑菌剂

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIBEKRAY等主编: "《基础食品微生物学 第4版》", 28 February 2014, 中国轻工业出版社 *
郭瑞华: ""1.5%的过氧化氢溶液作氧气湿化液的临床应用研究"", 《中外妇儿健康》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111838176A (zh) * 2020-08-05 2020-10-30 江苏中新瑞光学材料有限公司 一种氧气湿化液抑菌剂

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