CN106470683A - 针对犬心丝虫的抗蠕虫剂的用途 - Google Patents

针对犬心丝虫的抗蠕虫剂的用途 Download PDF

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Publication number
CN106470683A
CN106470683A CN201580037488.8A CN201580037488A CN106470683A CN 106470683 A CN106470683 A CN 106470683A CN 201580037488 A CN201580037488 A CN 201580037488A CN 106470683 A CN106470683 A CN 106470683A
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CN
China
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alkyl
optionally substituted
group
independently selected
alkoxy
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201580037488.8A
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English (en)
Chinese (zh)
Inventor
C.P.A.查斯赛宁
J.鲁茨
A.R.赫克奥斯
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Intervet International BV
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Intervet International BV
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Application filed by Intervet International BV filed Critical Intervet International BV
Publication of CN106470683A publication Critical patent/CN106470683A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201580037488.8A 2014-07-11 2015-07-10 针对犬心丝虫的抗蠕虫剂的用途 Pending CN106470683A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14176737 2014-07-11
EP14176737.6 2014-07-11
PCT/EP2015/065870 WO2016005577A1 (en) 2014-07-11 2015-07-10 Use of anthelmintic agents against dirofilaria immitis

Publications (1)

Publication Number Publication Date
CN106470683A true CN106470683A (zh) 2017-03-01

Family

ID=51167759

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580037488.8A Pending CN106470683A (zh) 2014-07-11 2015-07-10 针对犬心丝虫的抗蠕虫剂的用途

Country Status (7)

Country Link
US (1) US20170196854A1 (enExample)
EP (1) EP3166605A1 (enExample)
JP (1) JP2017519801A (enExample)
CN (1) CN106470683A (enExample)
AU (1) AU2015286635A1 (enExample)
BR (1) BR112017000520A2 (enExample)
WO (1) WO2016005577A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113354660A (zh) * 2020-03-06 2021-09-07 广州再极医药科技有限公司 噻吩并嘧啶类衍生物及其制备方法
CN114206860A (zh) * 2019-06-07 2022-03-18 礼蓝动物保健有限公司 用于治疗体内寄生虫的双环衍生物

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11014927B2 (en) 2017-03-20 2021-05-25 Forma Therapeutics, Inc. Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators
JOP20190223A1 (ar) 2017-04-01 2019-09-26 Novartis Ag عملية لتحضير حمض 1-(4- ميثان سلفونيل -2- تراي فلورو ميثيل - بنزيل)-2- ميثيل -1h- بيرولو [2، 3-b] بيريدين -3- يل- أسيتيك
US12053458B2 (en) 2018-09-19 2024-08-06 Novo Nordisk Health Care Ag Treating sickle cell disease with a pyruvate kinase R activating compound
ES2989438T3 (es) 2018-09-19 2024-11-26 Novo Nordisk Healthcare Ag Activación de la piruvato cinasa R
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
EP4031132A4 (en) 2019-09-19 2023-09-13 Forma Therapeutics, Inc. Activating pyruvate kinase r
EP4110336A4 (en) 2020-02-28 2024-06-05 Auburn University SIGNATURES OF DIROFILARIA VOLATILE ORGANIC COMPOUNDS AND THEIR USES
US12128035B2 (en) 2021-03-19 2024-10-29 Novo Nordisk Health Care Ag Activating pyruvate kinase R

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115688A1 (en) * 2009-03-20 2010-10-14 Intervet International B.V. Anthelmintic agents and their use
WO2010146083A1 (en) * 2009-06-18 2010-12-23 Intervet International B.V. Anthelmintic agents and their use
WO2014081697A2 (en) * 2012-11-20 2014-05-30 Merial Limited Anthelmintic compounds and compositions and method of using thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200938203A (en) * 2007-12-17 2009-09-16 Intervet Int Bv Anthelmintic agents and their use
EP2468096A1 (en) * 2010-12-21 2012-06-27 Intervet International BV Anthelmintic combinations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115688A1 (en) * 2009-03-20 2010-10-14 Intervet International B.V. Anthelmintic agents and their use
WO2010146083A1 (en) * 2009-06-18 2010-12-23 Intervet International B.V. Anthelmintic agents and their use
WO2014081697A2 (en) * 2012-11-20 2014-05-30 Merial Limited Anthelmintic compounds and compositions and method of using thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114206860A (zh) * 2019-06-07 2022-03-18 礼蓝动物保健有限公司 用于治疗体内寄生虫的双环衍生物
US12448391B2 (en) 2019-06-07 2025-10-21 Elanco Tiergesundheit Ag Bicyclic derivatives for treating endoparasites
CN113354660A (zh) * 2020-03-06 2021-09-07 广州再极医药科技有限公司 噻吩并嘧啶类衍生物及其制备方法
CN113354660B (zh) * 2020-03-06 2024-04-23 广州再极医药科技有限公司 噻吩并嘧啶类衍生物及其制备方法
TWI887367B (zh) * 2020-03-06 2025-06-21 大陸商北京再極醫藥科技有限公司 噻吩并嘧啶類衍生物及其製備方法
US12473300B2 (en) 2020-03-06 2025-11-18 Guangzhou Maxinovel Pharmaceuticals Co., Ltd. Thienopyrimidine derivative and preparation method therefor

Also Published As

Publication number Publication date
JP2017519801A (ja) 2017-07-20
US20170196854A1 (en) 2017-07-13
AU2015286635A1 (en) 2017-01-19
WO2016005577A1 (en) 2016-01-14
BR112017000520A2 (pt) 2017-11-14
EP3166605A1 (en) 2017-05-17

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Application publication date: 20170301