CN106456805B - 重组单纯疱疹病毒2(hsv-2)疫苗载体 - Google Patents

重组单纯疱疹病毒2(hsv-2)疫苗载体 Download PDF

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CN106456805B
CN106456805B CN201580022222.6A CN201580022222A CN106456805B CN 106456805 B CN106456805 B CN 106456805B CN 201580022222 A CN201580022222 A CN 201580022222A CN 106456805 B CN106456805 B CN 106456805B
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hsv
glycoprotein
recombinant
virus
genome
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CN106456805A (zh
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W·雅各布
P·A·冈萨雷斯穆诺茨
B·赫罗尔德
C·佩特罗
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Albert Einstein College of Medicine
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—DNA viruses
    • C07K16/085—Orthoherpesviridae (F), e.g. pseudorabies virus or Epstein-Barr virus
    • C07K16/087—Herpes simplex virus
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    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16671—Demonstrated in vivo effect

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CN201580022222.6A 2014-03-03 2015-03-02 重组单纯疱疹病毒2(hsv-2)疫苗载体 Active CN106456805B (zh)

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US10918712B2 (en) * 2014-03-03 2021-02-16 Albert Einstein College Of Medicine Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors
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WO2019213305A1 (en) * 2018-05-01 2019-11-07 Albert Einstein College Of Medicine HSV-2-DELTA-gD VACCINES AND METHODS FOR THEIR PRODUCTION AND USE
WO2020056411A1 (en) * 2018-09-14 2020-03-19 Excell Biotech, Llc Recombinant herpes simplex virus 1 (hsv-1)
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JP2022512747A (ja) * 2018-10-17 2022-02-07 アルベルト・アインシュタイン・カレッジ・オブ・メディシン 抗体依存性細胞傷害（ａｄｃｃ）を増強する方法
KR20240116556A (ko) * 2019-01-03 2024-07-29 앨버트 아인슈타인 컬리지 오브 메디신 재조합 단순 헤르페스 바이러스 2 (hsv-2) 백신 벡터를 사용한 면역의 수동 전달
WO2021207348A1 (en) * 2020-04-07 2021-10-14 Albert Einstein College Of Medicine Method of treating and preventing ocular disease with hsv-2 delta gd
IL298288B2 (en) * 2020-05-29 2025-03-01 Albert Einstein College Medicine Methods for using Delta-gD of single-stranded HSV-2 virus and recombinant HSV-2 glycoprotein D
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WO2023245159A1 (en) * 2022-06-16 2023-12-21 Albert Einstein College Of Medicine Recombinant herpes simplex virus 2 (hsv-2) vectors and engineered transgenic vero cell lines
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US20250222112A1 (en) * 2022-10-14 2025-07-10 Arizona Board Of Regents On Behalf Of Arizona State University Recombinant immune complexes targeting herpes simplex virus
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CN101583381A (zh) * 2006-09-08 2009-11-18 宾夕法尼亚大学董事会 Hsv-1和hsv-2疫苗和其使用方法

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CN106456805A (zh) 2017-02-22
US20170202952A1 (en) 2017-07-20
JP6652497B2 (ja) 2020-02-26
US20190111127A1 (en) 2019-04-18
JP2017510262A (ja) 2017-04-13
JP2020079245A (ja) 2020-05-28
CA2942166A1 (en) 2015-09-11
JP6844045B2 (ja) 2021-03-17
US10076568B2 (en) 2018-09-18
CN110938604B (zh) 2024-04-05
AU2020217310B2 (en) 2023-07-13
CN110938604A (zh) 2020-03-31
US10391165B2 (en) 2019-08-27
US20160158343A1 (en) 2016-06-09
AU2015225499B2 (en) 2020-05-14
EP3113801A4 (en) 2017-10-25
JP7050193B2 (ja) 2022-04-07
US20200023058A1 (en) 2020-01-23
EP3113801A2 (en) 2017-01-11
WO2015134368A2 (en) 2015-09-11
JP2021088590A (ja) 2021-06-10
US10751411B2 (en) 2020-08-25
US9999665B2 (en) 2018-06-19
US20200376114A1 (en) 2020-12-03
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WO2015134368A3 (en) 2015-11-26

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