CN106442702A - Thrombelastograph coagulation analyzer and application method thereof - Google Patents
Thrombelastograph coagulation analyzer and application method thereof Download PDFInfo
- Publication number
- CN106442702A CN106442702A CN201610754356.3A CN201610754356A CN106442702A CN 106442702 A CN106442702 A CN 106442702A CN 201610754356 A CN201610754356 A CN 201610754356A CN 106442702 A CN106442702 A CN 106442702A
- Authority
- CN
- China
- Prior art keywords
- support portion
- rotary shaft
- magnet
- moveable support
- fixed support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention provides a thrombelastograph coagulation analyzer and an application method thereof. The thrombelastograph coagulation analyzer comprises a movable supporting part, a fixed supporting part, a connecting part, a rotary shaft, a working magnetic body, a Hall element and a processing unit, wherein one end of the movable supporting part is fixedly connected with the rotary shaft and the other end of the movable supporting part is connected with the fixed supporting part through the connecting part; the movable supporting part is fixedly connected with the working magnetic body; the rotary shaft has rotation relative to the fixed supporting part under a driving effect of detected blood; the rotary shaft drives the movable supporting part to rotate; the movable supporting part drives the working magnetic body to move; the Hall element is connected with the processing unit; the Hall element is used for outputting a detection electric signal according to changes of a magnetic field of the working magnetic body; the processing unit is used for determining blood coagulation data of the detected blood according to the detection electric signal. According to the thrombelastograph coagulation analyzer and the application method thereof, provided by the invention, the accuracy of detecting the detected blood can be improved.
Description
Technical field
The present invention relates to detection technique field, particularly to a kind of thrombus elastometer and its using method.
Background technology
Thrombus elastometer is a kind of laboratory apparatus for vitro detection blood blood clotting, from platelet aggregation, blood coagulation, fibrinolytic
Etc. whole dynamic process, blood clotting process is monitored, thus obtaining blood clotting and the speed of fibrinolytic and the intensity of condensation.
Blood clotting can be used as the foundation of the clinical diagnosis of cardio-cerebrovascular diseases with the speed of fibrinolytic and the intensity of condensation.
In existing thrombus elastometer, the rotary shaft of thrombus elastometer is connected with rheostat, tested blood drives rotation
Axis of rotation, rotary shaft rotates and the resistance of rheostat output is changed, and the change of the resistance according to output is to tested blood
The blood clotting of liquid is detected.
Visible by foregoing description, in existing thrombus elastometer, rheostat output is made by the rotation of rotary shaft
Resistance changes, and the resistance that the change of tested blood is exported by rheostat embodies, but, rheostat is in the mistake using
Can temperature raise in journey, the rising of temperature can apply the resistance of output so that relatively low to the accuracy of the detection of tested blood.
Content of the invention
Embodiments provide a kind of thrombus elastometer and its using method, it is possible to increase detect the standard of tested blood
Really property.
In a first aspect, embodiments providing a kind of thrombus elastometer, including：
Moveable support portion, fixed support portion, connecting portion, rotary shaft, working magnet, Hall element, processing unit；
The one end in described moveable support portion is fixedly connected with described rotary shaft, and the other end is propped up with described fixation by connecting portion
Support part connects；
Described moveable support portion is fixedly connected with described working magnet；
Described rotary shaft produces the rotation with respect to described fixed support portion under the driving effect of tested blood；
Described rotary shaft drives described moveable support portion to rotate；
Described moveable support portion drives described working magnet to move；
Described Hall element is connected with described processing unit；
Described Hall element, for the changes of magnetic field according to described working magnet, output detection electric signal；
Described processing unit, for according to described detection electric signal, determining the blood clotting data of described tested blood.
Further, described connecting portion includes：Rolling bearing；
The inner ring of described rolling bearing is fixedly connected with described moveable support portion；
The outer ring of described rolling bearing is fixedly connected with described fixed support portion.
Further, described connecting portion includes：Addendum cone, jewel bearing；
Described jewel bearing is fixed on described fixed support portion；
Described addendum cone is fixed in described moveable support portion；
Described addendum cone passes through a form contacting with described jewel bearing and is connected.
Further, described connecting portion includes：First magnet, the second magnet；
Described first magnet is fixed on described fixed support portion；
Described second magnet is fixed in described moveable support portion；
Form magnetic suspension so that described fixed support portion is movable with described between described first magnet and described second magnet
Supporting part is connected by magnetic suspension.
Further, also include：At least one hairspring spring；
The inner ring of described hairspring spring is fixedly connected with the outer circumference surface of described rotary shaft；
The outer ring of described hairspring spring is fixedly connected with described fixed support portion；
Described hairspring spring, for, after described rotary shaft rotates deviation equilbrium position, producing makes described rotary shaft
The active force rotating to described equilbrium position direction.
Further, also include：Rail plate, sliding part, motor；
Described sliding part is connected with described rail plate；
Described motor is connected with described sliding part；
Described sliding part is connected with described fixed support portion；
Described motor, for receiving control signal, drives described sliding part to lead along described slip according to described control signal
Sliding in the direction of rail, drives described rotary shaft to slide along the direction of described rail plate.
Further, described processing unit, for the amplitude according to described detection electric signal and formula one, determines described rotation
The rotational angle of rotating shaft, determines the blood clotting data of described tested blood according to described rotational angle；
Wherein, formula one is：W=D × I, wherein, W is described rotational angle, and I is the amplitude of described detection electric signal, D
For detecting the amplitude of electric signal and the proportionality coefficient of rotational angle.
Further, also include：Described Hall element is fixedly connected with described fixed support portion.
Further, also include：The N pole of described working magnet and S pole are on the same face.
Second aspect, embodiments provides a kind of user of arbitrary described thrombus elastometer in first aspect
Method, including：
Described rotary shaft is placed in tested blood；
By rotary shaft described in described tested blood drive, described rotary shaft is made to produce with respect to described fixed support portion
Rotate；
Described moveable support portion is driven to rotate by described rotary shaft；
Described working magnet is driven to move by described moveable support portion；
By described Hall element according to the changes of magnetic field of described working magnet, export detection electric signal；
Using described processing unit according to described detection electric signal, determine the blood clotting data of described tested blood.
Further, when described thrombus elastometer includes：When rail plate, sliding part, motor,
Described described rotary shaft is placed in tested blood, including：
Send control signal to described motor, make described motor drive described sliding part edge according to according to described control signal
Sliding in the direction of described rail plate, so that a part for described rotary shaft is placed in described tested blood.
In embodiments of the present invention, rotary shaft produces turning with respect to fixed support portion under the driving effect of tested blood
Dynamic, rotary shaft drives moveable support portion to rotate, and moveable support portion drives working magnet to move, working magnet movement make work
The magnetic field of magnet changes, Hall element according to the changes of magnetic field of working magnet output detection electric signal, processing unit according to
Detection electric signal determines the blood clotting data of tested blood, the good stability of Hall element, high precision, and the magnetic field of working magnet is become
The detection changed is affected by the surrounding environment less, improves the accuracy detecting tested blood.
Brief description
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
Have technology description in required use accompanying drawing be briefly described it should be apparent that, drawings in the following description are the present invention
Some embodiments, for those of ordinary skill in the art, on the premise of not paying creative work, can also basis
These accompanying drawings obtain other accompanying drawings.
Fig. 1 is a kind of schematic diagram of thrombus elastometer that one embodiment of the invention provides；
Fig. 2 is the schematic diagram of another kind of thrombus elastometer that one embodiment of the invention provides；
Fig. 3 is a kind of flow chart of the using method of thrombus elastometer that one embodiment of the invention provides.
Specific embodiment
Purpose, technical scheme and advantage for making the embodiment of the present invention are clearer, below in conjunction with the embodiment of the present invention
In accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described it is clear that described embodiment is
The a part of embodiment of the present invention, rather than whole embodiments, based on the embodiment in the present invention, those of ordinary skill in the art
The every other embodiment being obtained on the premise of not making creative work, broadly falls into the scope of protection of the invention.
As shown in figure 1, embodiments providing a kind of thrombus elastometer, including：
Moveable support portion 101, fixed support portion 102, connecting portion 103, rotary shaft 104, working magnet 105, Hall element
106th, processing unit 107；
The one end in described moveable support portion 101 is fixedly connected with described rotary shaft 104, the other end pass through connecting portion 103 with
Described fixed support portion 102 connects；
Described moveable support portion 101 is fixedly connected with described working magnet 105；
Described rotary shaft 104 produces the rotation with respect to described fixed support portion 102 under the driving effect of tested blood；
Described rotary shaft 104 drives described moveable support portion 101 to rotate；
Described moveable support portion 101 drives described working magnet 105 mobile；
Described Hall element 106 is connected with described processing unit 107；
Described Hall element 106, for the changes of magnetic field according to described working magnet 105, output detection electric signal；
Described processing unit 107, for according to described detection electric signal, determining the blood clotting data of described tested blood.
In embodiments of the present invention, rotary shaft produces turning with respect to fixed support portion under the driving effect of tested blood
Dynamic, rotary shaft drives moveable support portion to rotate, and moveable support portion drives working magnet to move, working magnet movement make work
The magnetic field of magnet changes, Hall element according to the changes of magnetic field of working magnet output detection electric signal, processing unit according to
Detection electric signal determines the blood clotting data of tested blood, the good stability of Hall element, high precision, and the magnetic field of working magnet is become
The detection changed is affected by the surrounding environment less, improves the accuracy detecting tested blood.
In embodiments of the present invention, fixed support portion in the vertical direction is played a supporting role to moveable support portion, in order to
Make the blood clotting data of tested blood more accurate, need to reduce the frictional force with fixed support portion when moveable support portion rotates.
In order to reduce the frictional force between moveable support portion and fixed support portion, the connecting portion in the embodiment of the present invention can pass through following
Mode is realized：
In an embodiment of the invention, described connecting portion includes：Rolling bearing；
The inner ring of described rolling bearing is fixedly connected with described moveable support portion；
The outer ring of described rolling bearing is fixedly connected with described fixed support portion.
In embodiments of the present invention, it is rolling element between the inner ring of rolling bearing and outer ring, this rolling element can be ball
Deng outer ring is fixedly connected with fixed support portion, remains stationary as, and inner ring is fixedly connected with moveable support portion, with moveable support portion
Rotate.Rotary shaft produces the rotation with respect to fixed support portion under the driving effect of tested blood, and rotary shaft drives movable
Support part rotates, and reduces the frictional force in moveable support portion and fixed support portion by rolling bearing, reduces frictional force to movable
The impact that supporting part rotates, and then reduce the impact of the changes of magnetic field to working magnet for the frictional force so that making the magnetic field of magnet
Change more accurately reflects the blood clotting data of tested blood.
In an embodiment of the invention, described connecting portion includes：Addendum cone, jewel bearing；
Described jewel bearing is fixed on described fixed support portion；
Described addendum cone is fixed in described moveable support portion；
Described addendum cone passes through a form contacting with described jewel bearing and is connected.
In embodiments of the present invention, jewel bearing can be round pie structure, sets in a plane of round pie structure
Be equipped with conical socket, addendum cone can be cone structure, the tip of addendum cone is located in the conical socket on jewel bearing, addendum cone with precious
The point contact form that stone bearing is less than preset area with contact area is connected.
In embodiments of the present invention, rotary shaft produces turning with respect to fixed support portion under the driving effect of tested blood
Dynamic, rotary shaft drives moveable support portion to rotate, and moveable support portion is rotated with connecting portion for axle, in connecting portion, due to top
Cone is less with the contact area of jewel bearing, and therefore, addendum cone is less with the frictional force of jewel bearing, when moveable support portion is with rotation
During axis of rotation, frictional force is less to the resistance rotating, and then reduces the impact of the changes of magnetic field to working magnet for the frictional force,
The changes of magnetic field making working magnet more accurately reflects the blood clotting data of tested blood.
In order to reduce the frictional force between cone and jewel bearing further, also include：3rd magnet, the 4th magnet；
Described 3rd magnet is fixed on described fixed support portion；
Described 4th magnet is fixed in described moveable support portion；
Mutual exclusion between described 3rd magnet and described 4th magnet is so that rubbing between described addendum cone and described jewel bearing
Wiping power reduces.
In embodiments of the present invention, by the interaction force between the 3rd magnet and the 4th magnet, so that addendum cone
Pressure and jewel bearing between reduces, and then reduces frictional force between addendum cone and jewel bearing so that frictional force is to can
The resistance of the rotation of dynamic supporting part is less.For example, the 3rd magnet and the 4th magnet are parallel to each other, and are located with jewel bearing
Plane parallel.In the vertical direction, moveable support portion is by the active force of addendum cone and jewel bearing in the vertical direction, Yi Ji
Active force between three magnets and the 4th magnet is supported, and so, reduces addendum cone and jewel bearing in the vertical direction
Active force, and then reduce the frictional force between addendum cone and jewel bearing.
In an embodiment of the invention, described connecting portion includes：First magnet, the second magnet；
Described first magnet is fixed on described fixed support portion；
Described second magnet is fixed in described moveable support portion；
Form magnetic suspension so that described fixed support portion is movable with described between described first magnet and described second magnet
Supporting part is connected by magnetic suspension.
Moveable support portion is mainly coupled together so that moveable support portion can by the effect of connecting portion with fixed support portion
Rotated under the support of fixed support portion.In embodiments of the present invention, by the phase between the first magnet and the second magnet
Interreaction force moveable support portion is supported, after the first magnet and the second magnet form magnetic suspension, the first magnet and the
It is not in contact between two magnets, there is not frictional force.Rotary shaft produces with respect to fixing under the driving effect of tested blood
The rotation of support part, rotary shaft drives moveable support portion to rotate, and moveable support portion carries out turning in the presence of the magnetic suspension of connecting portion
Dynamic, in connecting portion, due to there is not frictional force between the first magnet and the second magnet, so to the rotation in moveable support portion
Resistance is less, and then makes the changes of magnetic field of working magnet more accurately reflect the blood clotting data of tested blood.
For example, the first magnet and the second magnet are parallel to each other, and the active force between the first magnet and the second magnet exists
Moveable support portion can be supported on vertical direction, and not contact between the first magnet and the second magnet, form magnetic suspension.
In an embodiment of the present invention, also include：At least one hairspring spring；
The inner ring of described hairspring spring is fixedly connected with the outer circumference surface of described rotary shaft；
The outer ring of described hairspring spring is fixedly connected with described fixed support portion；
Described hairspring spring, for, after described rotary shaft rotates deviation equilbrium position, producing makes described rotary shaft
The active force rotating to described equilbrium position direction.
In embodiments of the present invention, the inner ring of hairspring spring and rotary shaft phase are fixed, and outer ring is connected with fixed support portion,
When rotary shaft rotates deviation equilbrium position under the driving of tested blood, hairspring spring is tightened or launches, hairspring bullet
Spring deformation produce recover elastic force, when tested blood driving effect remove after, rotary shaft recover elastic force in the presence of recover to
It is achieved that the automatic calibration of rotary shaft, the mode that need not be manually operated is calibrated to rotary shaft for equilbrium position, thus
Further increase, during the follow-on test tested blood of difference, the efficiency that tested blood blood clotting is detected.
In embodiments of the present invention, when thrombus elastometer includes at least two hairspring springs, at least two hairspring bullets
The hand of spiral of spring is contrary.So, when rotating, there is the hairspring spring being tightened and the hairspring bullet being unfolded in rotary shaft simultaneously
Spring, improves the service life of hairspring spring it is ensured that the rotation of rotary shaft is more steady.
In an embodiment of the present invention, also include：Rail plate, sliding part, motor；
Described sliding part is connected with described rail plate；
Described motor is connected with described sliding part；
Described sliding part is connected with described fixed support portion；
Described motor, for receiving control signal, drives described sliding part to lead along described slip according to described control signal
Sliding in the direction of rail, drives described rotary shaft to slide along the direction of described rail plate.
In embodiments of the present invention, after motor receives control signal, Motor drive sliding part is along the direction of rail plate
Slide, because sliding part is connected with fixed support portion, sliding part drives fixed support portion to slide along the direction of rail plate, by
It is connected by connecting portion with moveable support portion in fixed support portion, fixed support portion drives moveable support portion along rail plate
Slide in direction, because moveable support portion is fixedly connected with rotary shaft, moveable support portion is rotated axle along the side of rail plate
To slip, slide along the direction of rail plate with rotary shaft, rotary shaft can be inserted tested blood or from tested blood
Middle taking-up.The motion of axle rotary shaft in this embodiment, is rotated by motor, without manual hand manipulation, convenient
The use of thrombus elastometer.
In an embodiment of the present invention, described processing unit, for according to described detection electric signal, determining described rotary shaft
Rotational angle, determine the blood clotting data of described tested blood according to described rotational angle.
Wherein, detection electric signal can be voltage or electric current.
In an embodiment of the present invention, described processing unit, for the amplitude according to described detection electric signal and formula one,
Determine the rotational angle of described rotary shaft, determine the blood clotting data of described tested blood according to described rotational angle；
Wherein, formula one is：W=D × I, wherein, W is described rotational angle, and I is the amplitude of described detection electric signal, D
For detecting the amplitude of electric signal and the proportionality coefficient of rotational angle.
In embodiments of the present invention, detection electric signal can be voltage or electric current；The amplitude of detection electric signal and rotation
The proportionality coefficient of angle can conclude out with the historical data of corresponding rotational angle by detecting the amplitude of electric signal, also may be used
Rule of thumb to obtain.
In an embodiment of the present invention, also include：Described Hall element is fixedly connected with described fixed support portion.
In the present embodiment, Hall element is fixedly connected with fixed support portion, because Hall element is constant, works as work
Magnet moves with moveable support portion, and Hall element can accurately detect the changes of magnetic field of working magnet.
In an embodiment of the present invention, also include：The N pole of described working magnet and S pole are on the same face.
Specifically, working magnet is disc, the N extremely semicircle of working magnet, the S extremely semicircle of working magnet.Work
Magnet is bar shaped, the half of the N extremely bar shaped of working magnet, the half of the S extremely bar shaped of working magnet.
In an embodiment of the present invention, working magnet is annulus row, N pole and the distribution of S pole uniform intervals on working magnet.
In addition, so that Hall element can more accurately detect the changes of magnetic field of working magnet, working magnet
Surface is parallel with the surface of Hall element.
As shown in Fig. 2 embodiments providing a kind of thrombus elastometer, including：
Moveable support portion 201, fixed support portion 202, connecting portion, rotary shaft 203, working magnet 204, Hall element 205,
Processing unit 206, the first hairspring spring 209, the second hairspring spring 210；
Connecting portion includes：Addendum cone 207, jewel bearing 208；
Jewel bearing 208 is fixed on fixed support portion 202；
Addendum cone 207 is fixed in moveable support portion 201；
Addendum cone 207 passes through a form contacting with jewel bearing 208 and is connected；
The one end in moveable support portion 201 is fixedly connected with rotary shaft 203；
Hall element 205 is fixedly connected with fixed support portion 202；
Moveable support portion 201 is fixedly connected with working magnet 204；
The inner ring of the first hairspring spring 209 and the second hairspring spring 210 is all fixing with the outer circumference surface of rotary shaft 203 even
Connect；
First hairspring spring 209 is all fixedly connected with fixed support portion 202 with the outer ring of the second hairspring spring 210；
First hairspring spring 209 and the second hairspring spring 210, are used to rotate deviation balance position in rotary shaft 203
Postpone, produce the active force making rotary shaft 203 rotate to equilbrium position direction.
Rotary shaft 203 produces the rotation with respect to fixed support portion 202 under the driving effect of tested blood；
Rotary shaft 203 drives moveable support portion 201 to rotate；
Moveable support portion 201 drives working magnet 204 to rotate；
Hall element 205 is connected with processing unit 206；
Hall element 205, for the changes of magnetic field according to working magnet 204, output detection electric signal；
Processing unit 206, for according to detection electric signal, determining the blood clotting data of tested blood.
Wherein, the N pole of working magnet 204 and S pole is on the same face, the first hairspring spring 209 and the second hairspring spring 210
The hand of spiral contrary.
In embodiments of the present invention, Hall element can export detection electric signal according to the magnetic induction intensity of working magnet；
Here detection electric signal can be voltage or electric current.When using Hall element, can first Hall element energising be preset
Duration, after making Hall element stable, begins to use thrombus elastometer.
In embodiments of the present invention, when using thrombus elastometer, rotary shaft is placed into the container holding tested blood
In, this container is rotated with external motivating force, and tested blood also rotates with container, tested blood drive rotary shaft
Produce the rotation with respect to fixed support portion, rotary shaft drives moveable support portion to rotate；Moveable support portion drives working magnet to turn
Dynamic；With the rotation of working magnet, Hall element detects the changes of magnetic field of working magnet, output detection electric signal；Process single
Unit, according to detection electric signal, determines the blood clotting data of tested blood.
Wherein, the container holding tested blood includes heater, and this container can heat to tested blood, makes
Tested blood is within the scope of default temperature it is ensured that residing temperature during tested blood blood clotting and human body temperature phase
Seemingly, improve the accuracy of test result.
Processing unit, can be specifically for according to detection electric signal, determining rotation when determining the blood clotting data of tested blood
The rotational angle of rotating shaft, determines the blood clotting data of tested blood according to the rotational angle of rotary shaft.
Working magnet in the embodiment of the present invention can be including：Permanent-magnet steel, for example：No. II magnet steel of neodymium iron boron.
In addition, the connecting portion in the embodiment of the present invention can also be realized by the first magnet and the second magnet or logical
Cross rolling bearing to realize.
As shown in figure 3, embodiments providing a kind of arbitrary thrombus elastometer provided in an embodiment of the present invention
Using method, including：
Step 301：Rotary shaft is placed in tested blood；
Step 302：By rotary shaft described in described tested blood drive, described rotary shaft is made to produce with respect to described fixation
The rotation of supporting part；
Step 303：Described moveable support portion is driven to rotate by described rotary shaft；
Step 304：Described working magnet is driven to move by described moveable support portion；
Step 305：By described Hall element according to the changes of magnetic field of described working magnet, export detection electric signal；
Step 306：Using described processing unit according to described detection electric signal, determine the blood clotting number of described tested blood
According to.
In an embodiment of the present invention, when described thrombus elastometer includes：When rail plate, sliding part, motor,
Described described rotary shaft is placed in tested blood, including：
Send control signal to described motor, make described motor drive described sliding part edge according to according to described control signal
Sliding in the direction of described rail plate, so that a part for described rotary shaft is placed in described tested blood.
Each embodiment of the present invention at least has the advantages that：
1st, in embodiments of the present invention, rotary shaft produces with respect to fixed support portion under the driving effect of tested blood
Rotate, rotary shaft drive moveable support portion rotate, moveable support portion drive working magnet move, working magnet movement make work
The magnetic field making magnet changes, and Hall element is according to the changes of magnetic field output detection electric signal of working magnet, processing unit root
Determine the blood clotting data of tested blood, the good stability of Hall element, high precision, the magnetic field to working magnet according to detection electric signal
The detection of change is affected by the surrounding environment less, improves the accuracy detecting tested blood.
2nd, in embodiments of the present invention, the frictional force in moveable support portion and fixed support portion is reduced by rolling bearing,
Reduce the impact that frictional force rotates to moveable support portion, and then reduce the shadow of the changes of magnetic field to working magnet for the frictional force
Ring so that the changes of magnetic field making magnet more accurately reflects the blood clotting data of tested blood.
3rd, in embodiments of the present invention, rotary shaft produces with respect to fixed support portion under the driving effect of tested blood
Rotate, rotary shaft drives moveable support portion to rotate, and moveable support portion is rotated with connecting portion for axle, in connecting portion, due to
Addendum cone is less with the contact area of jewel bearing, and therefore, addendum cone is less with the frictional force of jewel bearing, when moveable support portion with
When rotary shaft rotates, frictional force is less to the resistance rotating, and then reduces the shadow of the changes of magnetic field to working magnet for the frictional force
Ring so that the changes of magnetic field of working magnet more accurately reflects the blood clotting data of tested blood.
4th, in embodiments of the present invention, by the interaction force between the first magnet and the second magnet come to moveable support
Portion is supported, and after the first magnet and the second magnet form magnetic suspension, is not in contact with, no between the first magnet and the second magnet
There is frictional force.Rotary shaft produces the rotation with respect to fixed support portion under the driving effect of tested blood, and rotary shaft drives
Moveable support portion rotates, and moveable support portion is rotated in the presence of the magnetic suspension of connecting portion, in connecting portion, due to first
There is not frictional force between magnet and the second magnet, thus less to the resistance of the rotation in moveable support portion, and then make work
The changes of magnetic field of magnet more accurately reflects the blood clotting data of tested blood.
It should be noted that herein, such as first and second etc relational terms are used merely to an entity
Or operation is made a distinction with another entity or operation, and not necessarily requires or imply exist between these entities or operation
Any this actual relation or order.And, term " inclusion ", "comprising" or its any other variant are intended to non-
The comprising of exclusiveness, so that including a series of process of key elements, method, article or equipment not only include those key elements,
But also include other key elements being not expressly set out, or also include being consolidated by this process, method, article or equipment
Some key elements.In the absence of more restrictions, the key element being limited by sentence " including ", does not arrange
Remove and also there is other identical factor in the process including described key element, method, article or equipment.
One of ordinary skill in the art will appreciate that：The all or part of step realizing said method embodiment can be passed through
Completing, aforesaid program can be stored in the storage medium of embodied on computer readable the related hardware of programmed instruction, this program
Upon execution, execute the step including said method embodiment；And aforesaid storage medium includes：ROM, RAM, magnetic disc or light
Disk etc. is various can be with the medium of store program codes.
Last it should be noted that：The foregoing is only presently preferred embodiments of the present invention, be merely to illustrate the skill of the present invention
Art scheme, is not intended to limit protection scope of the present invention.All any modifications made within the spirit and principles in the present invention,
Equivalent, improvement etc., are all contained in protection scope of the present invention.
Claims (10)
1. a kind of thrombus elastometer is it is characterised in that include：
Moveable support portion, fixed support portion, connecting portion, rotary shaft, working magnet, Hall element, processing unit；
The one end in described moveable support portion is fixedly connected with described rotary shaft, and the other end passes through connecting portion and described fixed support portion
Connect；
Described moveable support portion is fixedly connected with described working magnet；
Described rotary shaft produces the rotation with respect to described fixed support portion under the driving effect of tested blood；
Described rotary shaft drives described moveable support portion to rotate；
Described moveable support portion drives described working magnet to move；
Described Hall element is connected with described processing unit；
Described Hall element, for the changes of magnetic field according to described working magnet, output detection electric signal；
Described processing unit, for according to described detection electric signal, determining the blood clotting data of described tested blood.
2. thrombus elastometer according to claim 1 it is characterised in that
Described connecting portion includes：Rolling bearing；
The inner ring of described rolling bearing is fixedly connected with described moveable support portion；
The outer ring of described rolling bearing is fixedly connected with described fixed support portion.
3. thrombus elastometer according to claim 1 it is characterised in that
Described connecting portion includes：Addendum cone, jewel bearing；
Described jewel bearing is fixed on described fixed support portion；
Described addendum cone is fixed in described moveable support portion；
Described addendum cone passes through a form contacting with described jewel bearing and is connected.
4. thrombus elastometer according to claim 1 it is characterised in that
Described connecting portion includes：First magnet, the second magnet；
Described first magnet is fixed on described fixed support portion；
Described second magnet is fixed in described moveable support portion；
Form magnetic suspension so that described fixed support portion and described moveable support between described first magnet and described second magnet
Portion is connected by magnetic suspension.
5. thrombus elastometer according to claim 1 it is characterised in that
Also include：At least one hairspring spring；
The inner ring of described hairspring spring is fixedly connected with the outer circumference surface of described rotary shaft；
The outer ring of described hairspring spring is fixedly connected with described fixed support portion；
Described hairspring spring, for, after described rotary shaft rotates deviation equilbrium position, producing makes described axial rotary institute
State the active force of equilbrium position direction rotation.
6. thrombus elastometer according to claim 1 it is characterised in that
Also include：Rail plate, sliding part, motor；
Described sliding part is connected with described rail plate；
Described motor is connected with described sliding part；
Described sliding part is connected with described fixed support portion；
Described motor, for receiving control signal, drives described sliding part along described rail plate according to described control signal
Sliding in direction, drives described rotary shaft to slide along the direction of described rail plate.
7. according to described thrombus elastometer arbitrary in claim 1-6 it is characterised in that
Described processing unit, for the amplitude according to described detection electric signal and formula one, determines the angle of rotation of described rotary shaft
Degree, determines the blood clotting data of described tested blood according to described rotational angle；
Wherein, formula one is：W=D × I, wherein, W is described rotational angle, and I is the amplitude of described detection electric signal, and D is inspection
Survey the amplitude of electric signal and the proportionality coefficient of rotational angle.
8. according to described thrombus elastometer arbitrary in claim 1-6 it is characterised in that
Also include：Described Hall element is fixedly connected with described fixed support portion；
And/or,
Also include：The N pole of described working magnet and S pole are on the same face.
9. in a kind of claim 1 to 8 arbitrary described thrombus elastometer using method it is characterised in that include：
Described rotary shaft is placed in tested blood；
By rotary shaft described in described tested blood drive, described rotary shaft is made to produce turning with respect to described fixed support portion
Dynamic；
Described moveable support portion is driven to rotate by described rotary shaft；
Described working magnet is driven to move by described moveable support portion；
By described Hall element according to the changes of magnetic field of described working magnet, export detection electric signal；
Using described processing unit according to described detection electric signal, determine the blood clotting data of described tested blood.
10. method according to claim 9 is it is characterised in that when described thrombus elastometer includes：Rail plate, slip
When portion, motor,
Described described rotary shaft is placed in tested blood, including：
Send control signal to described motor, make described motor drive described sliding part along described according to according to described control signal
Sliding in the direction of rail plate, so that a part for described rotary shaft is placed in described tested blood.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610754356.3A CN106442702A (en) | 2016-08-30 | 2016-08-30 | Thrombelastograph coagulation analyzer and application method thereof |
| US16/097,565 US11016013B2 (en) | 2016-04-29 | 2017-05-02 | Apparatus for measuring blood coagulation data, and use method and calibration method thereof |
| PCT/CN2017/082754 WO2017186183A1 (en) | 2016-04-29 | 2017-05-02 | Apparatus for measuring blood coagulation data, and use method and calibration method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610754356.3A CN106442702A (en) | 2016-08-30 | 2016-08-30 | Thrombelastograph coagulation analyzer and application method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106442702A true CN106442702A (en) | 2017-02-22 |
Family
ID=58090026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610754356.3A Pending CN106442702A (en) | 2016-04-29 | 2016-08-30 | Thrombelastograph coagulation analyzer and application method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106442702A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107024312A (en) * | 2017-05-15 | 2017-08-08 | 深圳麦科田生物医疗技术有限公司 | Detection means with micro- damping structure |
| WO2017186183A1 (en) * | 2016-04-29 | 2017-11-02 | 诺泰科生物科技（苏州）有限公司 | Apparatus for measuring blood coagulation data, and use method and calibration method thereof |
| CN109142698A (en) * | 2018-07-27 | 2019-01-04 | 深圳优迪生物技术有限公司 | Solution elasticity testing device |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4193293A (en) * | 1977-04-28 | 1980-03-18 | E.L.V.I. S.P.A. | Apparatus for determining blood elasticity parameters |
| CN201666795U (en) * | 2010-03-31 | 2010-12-08 | 比亚迪股份有限公司 | Angle sensor |
| CN102830041A (en) * | 2012-09-04 | 2012-12-19 | 济南美医林电子仪器有限公司 | Stepping scanning torque measuring device in magnetic-levitation bearing support structure |
| CN104181311A (en) * | 2014-08-22 | 2014-12-03 | 中国科学院苏州生物医学工程技术研究所 | Thrombus elasticity testing device |
| CN105807039A (en) * | 2016-04-29 | 2016-07-27 | 苏州品诺维新医疗科技有限公司 | Thrombus elastometer |
| CN105805176A (en) * | 2016-04-29 | 2016-07-27 | 苏州品诺维新医疗科技有限公司 | Stent, thrombelastogram instrument and supporting system |
-
2016
- 2016-08-30 CN CN201610754356.3A patent/CN106442702A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4193293A (en) * | 1977-04-28 | 1980-03-18 | E.L.V.I. S.P.A. | Apparatus for determining blood elasticity parameters |
| CN201666795U (en) * | 2010-03-31 | 2010-12-08 | 比亚迪股份有限公司 | Angle sensor |
| CN102830041A (en) * | 2012-09-04 | 2012-12-19 | 济南美医林电子仪器有限公司 | Stepping scanning torque measuring device in magnetic-levitation bearing support structure |
| CN104181311A (en) * | 2014-08-22 | 2014-12-03 | 中国科学院苏州生物医学工程技术研究所 | Thrombus elasticity testing device |
| CN105807039A (en) * | 2016-04-29 | 2016-07-27 | 苏州品诺维新医疗科技有限公司 | Thrombus elastometer |
| CN105805176A (en) * | 2016-04-29 | 2016-07-27 | 苏州品诺维新医疗科技有限公司 | Stent, thrombelastogram instrument and supporting system |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017186183A1 (en) * | 2016-04-29 | 2017-11-02 | 诺泰科生物科技（苏州）有限公司 | Apparatus for measuring blood coagulation data, and use method and calibration method thereof |
| US11016013B2 (en) | 2016-04-29 | 2021-05-25 | Neotek Bioscience Co., Ltd. | Apparatus for measuring blood coagulation data, and use method and calibration method thereof |
| CN107024312A (en) * | 2017-05-15 | 2017-08-08 | 深圳麦科田生物医疗技术有限公司 | Detection means with micro- damping structure |
| CN107024312B (en) * | 2017-05-15 | 2023-09-15 | 深圳麦科田生物医疗技术股份有限公司 | Detection device with micro damping structure |
| CN109142698A (en) * | 2018-07-27 | 2019-01-04 | 深圳优迪生物技术有限公司 | Solution elasticity testing device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104181311B (en) | A kind of thrombus elasticity testing device | |
| CN204065105U (en) | A kind of thrombus elasticity testing device | |
| CN106442702A (en) | Thrombelastograph coagulation analyzer and application method thereof | |
| CN103064039B (en) | High-precision method of magnetic field measurement for compact intermediate energy cyclothron | |
| CN103528676B (en) | A kind of semiconductor laser light intensity distribution testing method and device thereof | |
| CN102830041A (en) | Stepping scanning torque measuring device in magnetic-levitation bearing support structure | |
| CN105805176A (en) | Stent, thrombelastogram instrument and supporting system | |
| CN105091799A (en) | Coaxiality measuring system of motor end cover | |
| CN106705993A (en) | Micromechanical gyroscope swing arm type testing device | |
| CN105973130B (en) | Interlayer displacement angle measuring device | |
| CN108151697A (en) | A kind of drive shaft assembly pivot angle detection instrument | |
| CN102679939B (en) | Roundness detecting method for eccentric shaft part | |
| CN100501334C (en) | Swing arm type tester for micromechanical gyro | |
| CN207852158U (en) | Centripetal force test device in physics teaching experiment | |
| CN202048878U (en) | Moving angle measurer of air conditioner air door | |
| CN109596358A (en) | A kind of full-automatic bearing vibration velocity test device | |
| CN206269750U (en) | Ball screw assembly, helical pitch precision measurer | |
| CN203276404U (en) | Non-contact radio frequency IC card POS detecting device | |
| WO2017186188A1 (en) | Bracket,thrombelastography device, and support system | |
| CN207556521U (en) | A kind of drive shaft assembly pivot angle detection instrument | |
| CN106404888A (en) | Thromboelastography instrument and use method thereof | |
| CN106908620A (en) | A kind of haulage cable linear velocity detector | |
| CN102116615B (en) | Method for measuring roundness of eccentric part | |
| CN207689052U (en) | A kind of Torsion Pendulum system | |
| CN202372349U (en) | Bearing flexibility detection disk |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170222 |
|
| RJ01 | Rejection of invention patent application after publication |