CN106426909A - Quick-change type multi-station 3D printing spray head based on low-temperature colloidal biological material - Google Patents
Quick-change type multi-station 3D printing spray head based on low-temperature colloidal biological material Download PDFInfo
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- CN106426909A CN106426909A CN201611007012.2A CN201611007012A CN106426909A CN 106426909 A CN106426909 A CN 106426909A CN 201611007012 A CN201611007012 A CN 201611007012A CN 106426909 A CN106426909 A CN 106426909A
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- confession
- discharge tank
- storage vat
- quick
- material feeding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
Abstract
The invention provides a quick-change type multi-station 3D printing spray head based on a low-temperature colloidal biological material and belongs to the field of tissue engineering technologies and biological 3D printing. According to the quick-change type multi-station 3D printing spray head based on the low-temperature colloidal biological material, quick change of a nozzle among three stations is achieved through mutual movement among a material storage cylinder and a feeding/discharging cylinder, materials on the idle station are stored in the material storage cylinder, the materials enter the feeding/discharging cylinder through small holes in the lower portion of the feeding/discharging cylinder during the extrusion forming process, printing forming is achieved through a needle head, the materials on the material injection station enter the material storage cylinder through small holes in the upper portion of the feeding/discharging cylinder, and quick supplementing of the materials is completed. The quick-change type multi-station 3D printing spray head has the beneficial effects that for the type of the 3D printing spray head, liquid substances such as aqueous solutions, colloid and paste can be prepared; and multiple storage cylinders can be arranged on a printer, quick change among the multiple stations is achieved, and possibility is provided for combined printing of various biological materials.
Description
Technical field
Patent of the present invention relates to a kind of biological tissue and manufactures applicable biomaterial (for the preparation of collagen/nano-cellulose composite of dermal scaffold, jelly, in preparation process, need to avoid contacting high temperature) the quick-changing type multistation 3D printing head structure of the pneumatic control of condensation extrusion modling, for the printing of Cell and organism material, belong to tissue engineering technique and biological 3D and print field.
Background technology
225009 No.88, College South Road, Yangzhou City, Jiangsu Province treatment means. but owing to there being the shortage of organ donor source, the problems such as immunological rejection, organ transplant is in actual utilization the difficulty that existence is difficult to overcome. the proposition of organizational project is for addressing the above problem the approach that provides new. and organizational project is by work cell is by conforming to someway on the biological support of biomaterial matrix or artificial preparation, constructing function tissue substitute thing. by organizer's substitute of structure is cultivated in rear patients with implantation body, substitute the side of original pathological tissues organ method is recovered original physical function, realizing the treatment to patient. the research of organization engineering skin at present and utilization are exactly tissue effective illustration of the good development prospect of engineering.
Traditional Tissue Engineering Study is subject to the restriction of cell implanted prosthetics always, " cell is implanted on support " in this sport technique segment, different types of biological material and cell cannot be navigated to exactly to the diverse location of internal stent on. in fact, along with the development of Tissue Engineering Study, research work is prolonged life to bulk soft tissue and internal organs aspect gradually, these tissues and organ often need to be made up of various kinds of cell and biomaterial, different cells or material have again separately spatial arrangement, therefore the problem that above-mentioned technical limitation causes highlights more.
In recent years, the fast development of 3D printing technique, open up new manufacture production model .3D for industry manufacture and printed skill the popularization of art, also a lot of new application in biological field, have been obtained, biomaterial is printed, the technology such as cell three-dimensional controlled tissue also to arise at the historic moment. these technology can operate for individual cells or single composition microsize drop, accurately control behaviour do the locus of object, this is for the space of realizing Cell and organism material not of the same race in bulk tissue and organ building process therefore, biometric print technology is the inexorable trend of future organization engineering research, if overcome. position deposition has huge meaning the problem that meets printing under different temperatures environment of different materials, just can realize the rapid shaping of bulk tissue and organ. in a typical biometric print machine, shower nozzle and feed, storage device is that the core of printer capability embodies.
The biological 3D printing head of the rotation switching mode of printing towards multiple material of Zhejiang University's research has been realized the printing of single spraying head to multiple material, feasible for some high-temperature materials, but for some cryogenic materials or colloidal material, the composite printing of realizing multiple material still has difficulties.
Summary of the invention
The object of the invention is: for the biomaterial that needs condensation extruding, particularly collagen/nanofiber etc. below 30 DEG C, could better ensure the composite of material property in temperature, provide one based on the gluey biomaterial 3D of low temperature the quick-changing type multistation shower nozzle of printing. by ensureing under Pneumatic extrusion that extruding condensed material has good mechanical property and structure feature, simultaneously by pneumatic control rapid adjustment shower nozzle, make in the free time, extruding, between three stations such as material feeding, realize fast and switching, realize the composite printing of multiple material, improve production efficiency, for the design of this kind equipment later provides reference function.
Technical scheme of the present invention is: the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature, its spy Levy and be, comprise lower sealing hollow storage vat, confession/discharge tank, be connected in the syringe needle of confession/discharge tank lower end, described storage vat Center is longitudinally provided with the cavity that confession/discharge tank is installed, and confession/discharge tank inserts in this cavity, and can move up and down, and cavity The sidewall of chamber wall and confession/discharge tank fit, described syringe needle communicates with confession/discharge tank inside;
Wall top, chamber, the wall bottom, chamber of described storage vat cavity are respectively equipped with aperture, the top of described confession/discharge tank sidewall, under Portion is also respectively equipped with aperture, and the upper and lower hole pitch-row of confession/discharge tank is less than the upper and lower hole pitch-row of storage vat;
Described storage vat top is connected with pressurizing unit or material injecting device, described pressurizing unit comprise extruding upper cover, extruding lower cover, The composite printing of realizing multiple material, has improved production efficiency, for the design of this kind equipment later provides reference function Confession/discharge tank top is connected and fixed, and extruding lower cover and storage vat top are connected and fixed; Described extruding upper cover place is provided with and is connected in not With Pneumatic valve mouth 1 and the Pneumatic valve mouth 2 of air compressor, extruding upper cover, extruding lower cover, extrusion piston enclose formation airtight cavity, Pneumatic valve mouth 1 and this airtight cavity UNICOM, Pneumatic valve mouth 2 and the inner UNICOM of storage vat;
Described material injecting device comprises material feeding piston, material feeding lid, and material feeding piston is placed in material feeding lid, material feeding piston and confession/discharge tank Top is connected and fixed, and material feeding lid and storage vat top are connected and fixed; Material feeding lid place is provided with the air pressure valve that is connected in air compressor Mouth 3 and the hydraulic pressure valve port being connected with material feeding hydraulic press, material feeding piston, material feeding lid form airtight cavity, and Pneumatic valve mouth 3 is close with this Close cavity UNICOM, hydraulic pressure valve port and the inner UNICOM of confession/discharge tank;
When shower nozzle is in idle station: stagger mutually in the hole up and down of storage vat and the hole up and down of confession/discharge tank, now storage vat and When shower nozzle is in material feeding station;
When shower nozzle is in extrusion position: pressurizing unit is connected with storage vat, and Pneumatic valve mouth 1 air inlet promotes extrusion piston and transports downwards Moving, confession/discharge tank bottom aperture is overlapped with storage vat bottom aperture, Pneumatic valve mouth 2 air inlets, to input pressure in storage vat, push away Material in moving storage vat, in bottom aperture flows into confession/discharge tank, enters syringe needle and completes printing;
Confession/discharge tank is two spaces spaced apart from each other, material cannot circulate: material injecting device is connected with storage vat, bleed by Pneumatic valve mouth 3, material feeding piston rises together with confession/discharge tank, confession/discharge tank top aperture is overlapped with storage vat top aperture, material enters confession/discharge tank by hydraulic pressure valve port, and enters storage vat via confession/discharge tank top aperture, completes supplementing fast of material.
Described storage vat is vinyon material, and bottom is airtight tapered.
Described confession/discharge tank is that metal material is made.
The aperture, upper and lower hole of described storage vat cavity chamber wall is 3mm, pitch-row 30mm.
The aperture, upper and lower hole of described confession/discharge tank sidewall is 3mm, pitch-row 20mm.
Described storage vat is connected by electromagnetic relay with pressurizing unit or material injecting device.
Described storage vat top exterior walls is provided with flange, and iron plate is posted at this flange place, is convenient to electromagnetic relay and captures.
Described syringe needle adopts and is threaded onto confession/discharge tank lower end.
Described syringe needle is injection needle or self-control syringe needle.
The present invention utilize the mutual movement between storage vat and confession/discharge tank realize shower nozzle between three stations fast conversion, under idle station, material storing is in storage vat, in extrusion modling process, enter by the aperture of confession/discharge tank below confession/discharge tank, complete printing shaping by syringe needle, under material feeding station, material enters storing by the aperture of confession/discharge tank top bucket, complete supplementing fast of material. by confession/discharge tank storage vat and pressurizing unit, between material injecting device, pass through electromagnetism relay device connects, can realize the quick switching of different storage vats, by operated pneumatic valve control extrusion piston or material feeding piston, can be fast speed is switched the position of confession/discharge tank in storage vat, complete the quick switching of different station. only have when confession/discharge tank is in squeezing press station, and pneumatic valve port has been opened high pressure and has been entered storage vat by pressurizing unit, the fluent material promoting in barrel passes through shower nozzle ejection, when air door closure, gas in shower nozzle is released to be realized air pressure balance shower nozzle and stops spraying gas.
The beneficial effect of patent of the present invention: the shower nozzle aqueous solution to the utmost that the 3D of this type prints, colloid, the liquid substances such as slurry. can allow printer at multiple storage vats, between multiple stations, switch fast, for the composite printing of multiple biomaterial provides possibility.
Brief description of the drawings
Fig. 1 (a) and (b), (c) are the present invention's structure chart under idle station, extrusion position, material feeding station respectively;
Fig. 2 (a) and (b), (c) are the present invention's front view under idle station, extrusion position, material feeding station respectively;
Fig. 3 (a) and (b), (c) are the present invention's top view under idle station, extrusion position, material feeding station respectively;
Fig. 4 (a) and (b), (c) are the present invention's extrusion molding unit signal under idle station, extrusion position, material feeding station respectively Figure;
In figure: 1 storage vat, 2 confession/discharge tanks, 3 syringe needles, 4 extruding upper covers, 5 extruding lower covers, 6 extrusion pistons, 7 electromagnetic relays, 8 material feeding pistons, 9 material feeding lids, 10 Pneumatic valve mouth 1,11 Pneumatic valve mouth 2,12 Pneumatic valve mouth 3,13 hydraulic pressure valve ports.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, patent of the present invention is described further:
As shown in Figure 4, the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature, under idle station, storage vat 1 with aperture on confession/discharge tank 2 staggers mutually, now storage vat 1 and confession/discharge tank 2 are two spaces spaced apart from each other, logistics cannot circulate, before beginning print job, can prepare multiple storage vats, the multiple biomaterial of preparation in bucket, and according to biology extruding upper cover 4, extruding lower cover 5, extrusion piston 6 forms airtight cavity, connect air compressor by Pneumatic valve mouth 1, in extruding. under extrusion position, extrusion piston 6 and confession/discharge tank 2 are fixing, under extruding lid 5 and storage vat 1 are fixing, Pneumatic valve mouth 1 and Pneumatic valve mouth 2 connect respectively an air pressure input pipe, logistics can flow into through storage vat 1 under confession/discharge tank 2. material feeding stations, material feeding piston 8 is fixing with confession/discharge tank 2, material feeding lid 9 and storage vat 1 are fixing, Pneumatic valve mouth 3 be connected to air pressure input pipe, hydraulic pressure valve port is connected to filling tube and carries out the injection of material.
What syringe needle 3 adopted is threaded onto confession/discharge tank 2, what adopt is injection needle, also can make syringe needle by oneself. storage vat 1 is vinyon material, bottom is airtight tapered, inwall (cavity chamber wall) top and the bottom respectively have aperture, upper and lower hole aperture 3mm, pitch-row 30mm, iron plate is posted at storage vat outer wall flange place, being convenient to electromagnetic relay 7 captures. and confession/discharge tank 2 is metal material, and lower end can be threaded connection syringe needle 3, and confession/discharge tank 2 sidewall top and the bottom respectively have aperture, upper and lower hole aperture 3mm, pitch-row 20mm.
Confession/discharge tank 2 is installed on the middle vacancy of storage vat 1, confession/discharge tank 2 can move at storage vat 1 inner hollow place, the physics of material, chemical property are equipped with different needle covers, extruding lower cover 5, storage vat 1 form airtight cavity, connecting air compressor by Pneumatic valve mouth 2. when starting, extruding work promotes extrusion piston 6 by Pneumatic valve mouth 1 air inlet, shower nozzle is adjusted to extrusion position, completes extruding by the air in Pneumatic valve mouth 2 air inlet compression storage vats 1.
Material feeding piston 8, material feeding lid 9 form airtight cavity, connect aerostatic press by Pneumatic valve mouth 3, material feeding piston 8, confession/discharge tank 2, storage vat 1 form material feeding passage, connecting material feeding hydraulic press by hydraulic pressure valve port. when starting, material feeding work bleeds by Pneumatic valve mouth 3, shower nozzle is adjusted to material feeding station, by hydraulic pressure valve port to the interior injecting material of storage vat 1.
When extruding, operation principle is: before extruding, Pneumatic valve mouth 1 is connected respectively difference with Pneumatic valve mouth 2 by appendix air compression plant, air compressor provides gas pressure, carry out the size of controlled pressure and determine that material extrudes by Pressure gauge speed. after extruding lower cover 5 is connected by electromagnetic relay with storage vat 1, gas enters extruding upper cover 4 by Pneumatic valve mouth 1, cavity between extruding lower cover 5 and extrusion piston 6, promoting extrusion piston 6 moves downward, promote confession/discharge tank 2 move downward to extrusion position (confession/discharge tank bottom aperture overlaps with storage vat bottom aperture). air compressor starts by Pneumatic valve mouth 2 to storage vat input pressure, the material promoting in bucket flows into confession/discharge tank 2 through below aperture, enter syringe needle and complete printing.
When material feeding, operation principle is: before material feeding, Pneumatic valve mouth 3 connects air compressor, hydraulic pressure valve port is used for injecting material feeding, material feeding piston 8 captures confession/discharge tank 2 by electromagnetic relay, air compressor is by Pneumatic valve mouth 3 extracting airs, make material feeding piston 8 rise to material feeding station (confession/discharge tank top aperture overlaps with storage vat top aperture) together with confession/discharge tank 2. material enters confession/discharge tank 2 by hydraulic pressure valve port, and enter storage vat 1 via the aperture of confession/discharge tank 2 tops, complete supplementing fast of material.
Patent of the present invention discloses one, and to be applicable to operating temperature lower, raw material are gluey biomaterial extrusion modling quick-changing type multistation 3D printing head structure, storage vat shown in described extruding/control module comprises, confession/discharge tank, pin head, extruding upper cover, extruding lower cover, extrusion piston, material feeding lid, material feeding piston, confession/discharge tank is arranged on vacancy in storage vat, pin head is fixed on confession/discharge tank below. when extruding work, extruding upper cover, extruding lower cover, extrusion piston composition pressurizing unit, pass through electromagnetic relay captures storage vat, with extrusion piston adjustment confession/discharge tank station, the jet velocity of valve body control extruded material. when material feeding, material feeding lid connects storage vat, material feeding piston is captured confession/discharge tank and is adjusted its station by electromagnetic relay, hydraulic pressure valve control supplements raw material.
Claims (9)
1. a quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature, is characterized in that, comprises lower sealing Hollow storage vat (1), confession/discharge tank (2), the syringe needle (3) that is connected in confession/discharge tank lower end have the Pneumatic valve mouth 1 and the Pneumatic valve mouth 2 that are connected in different air compressors, extruding upper cover, extruding lower cover, extrusion piston enclose formation Longitudinally be provided with the cavity of confession/discharge tank is installed, confession/discharge tank inserts in this cavity, and can move up and down, and the chamber wall of cavity and The sidewall laminating of confession/discharge tank, described syringe needle communicates with confession/discharge tank inside;
Wall top, chamber, the wall bottom, chamber of described storage vat cavity are respectively equipped with aperture, the top of described confession/discharge tank sidewall, under Portion is also respectively equipped with aperture, and the upper and lower hole pitch-row of confession/discharge tank is less than the upper and lower hole pitch-row of storage vat;
Described storage vat top is connected with pressurizing unit or material injecting device, and described pressurizing unit comprises under extruding upper cover (4), extruding Lid (5), extrusion piston (6), extruding upper cover gland tops under annular extrusion, extrusion piston is placed in extruding lower cover, described in Extrusion piston and confession/discharge tank top are connected and fixed, and extruding lower cover and storage vat top are connected and fixed; Described extruding upper cover place establishes , described storage vat center Airtight cavity, Pneumatic valve mouth 1 and this airtight cavity UNICOM, Pneumatic valve mouth 2 and the inner UNICOM of storage vat;
Described material injecting device comprises material feeding piston (8), material feeding lid (9), and material feeding piston is placed in material feeding lid, material feeding piston and confession/ Discharge tank top is connected and fixed, and material feeding lid and storage vat top are connected and fixed; Material feeding lid place is provided with and is connected in air compressor Pneumatic valve mouth 3 and the hydraulic pressure valve port being connected with material feeding hydraulic press, material feeding piston, material feeding lid form airtight cavity, Pneumatic valve mouth 3 With this airtight cavity UNICOM, hydraulic pressure valve port and the inner UNICOM of confession/discharge tank;
When shower nozzle is in idle station: stagger mutually in the hole up and down of storage vat and the hole up and down of confession/discharge tank, now storage vat and Confession/discharge tank is two spaces spaced apart from each other, and material cannot circulate;
When shower nozzle is in extrusion position: pressurizing unit is connected with storage vat, and Pneumatic valve mouth 1 air inlet promotes extrusion piston and transports downwards Moving, confession/discharge tank bottom aperture is overlapped with storage vat bottom aperture, Pneumatic valve mouth 2 air inlets, to input pressure in storage vat, push away Material in moving storage vat, in bottom aperture flows into confession/discharge tank, enters syringe needle and completes printing;
When shower nozzle is in material feeding station: material injecting device is connected with storage vat, bleed by Pneumatic valve mouth 3, material feeding piston rises together with confession/discharge tank, confession/discharge tank top aperture is overlapped with storage vat top aperture, material enters confession/discharge tank by hydraulic pressure valve port, and enter storage vat via confession/discharge tank top aperture, complete supplementing fast of material.
2. the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature according to claim 1, is characterized in that, described storage vat is vinyon material, and bottom is airtight tapered.
3. the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature according to claim 1, is characterized in that, described confession/discharge tank is that metal material is made.
4. the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature according to claim 1, is characterized in that, the aperture, upper and lower hole of described storage vat cavity chamber wall is 3mm, pitch-row 30mm.
5. the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature according to claim 4, is characterized in that, the aperture, upper and lower hole of described confession/discharge tank sidewall is 3mm, pitch-row 20mm.
6. the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature according to claim 1, is characterized in that, described storage vat is connected by electromagnetic relay (7) with pressurizing unit or material injecting device.
Be, described storage vat top exterior walls is provided with flange, and iron plate is posted at this flange place, is convenient to electromagnetic relay and captures the 7. quick-changing type multistation shower nozzles of printing based on the gluey biomaterial 3D of low temperature according to claim 6, its feature.
8. the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature according to claim 1, is characterized in that, described syringe needle adopts and is threaded onto confession/discharge tank lower end.
9. according to the quick-changing type multistation shower nozzle of printing based on the gluey biomaterial 3D of low temperature described in claim 1 or 8, it is characterized in that, described syringe needle is injection needle or self-control syringe needle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611007012.2A CN106426909B (en) | 2016-11-16 | 2016-11-16 | Quick-changing type multistation nozzle based on low temperature glue biomaterial 3D printing |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611007012.2A CN106426909B (en) | 2016-11-16 | 2016-11-16 | Quick-changing type multistation nozzle based on low temperature glue biomaterial 3D printing |
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| CN106426909B CN106426909B (en) | 2018-07-03 |
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| Publication number | Publication date |
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| CN106426909B (en) | 2018-07-03 |
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