CN106421384A - Traditional Chinese medicinal preparation for treating senile chronic bronchitis - Google Patents

Traditional Chinese medicinal preparation for treating senile chronic bronchitis Download PDF

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Publication number
CN106421384A
CN106421384A CN201610869622.7A CN201610869622A CN106421384A CN 106421384 A CN106421384 A CN 106421384A CN 201610869622 A CN201610869622 A CN 201610869622A CN 106421384 A CN106421384 A CN 106421384A
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chronic bronchitis
chinese medicine
traditional chinese
senile chronic
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邓新平
黄庭宝
傅小妮
李小周
卢煜海
聂伊芷
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Guangxi University
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Guangxi University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/424Gynostemma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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Abstract

The invention belongs to the technical field of traditional Chinese medicine research and development, and in particular relates to a traditional Chinese medicinal preparation for treating senile chronic bronchitis. The traditional Chinese medicinal preparation is prepared from the following raw materials in parts by weight: 3-9 parts of corn cervi pantotrichum, 3-9 parts of root slices of common monkshood, 6-10 parts of radix morindae officinalis, 12-18 parts of trichosanthes peel, 15-30 parts of herba gynostemmae pentaphylli, 3-9 parts of herba pimpinellae thellungianae, 6-15 parts of fructus phellodendri, 10-15 parts of all-grass of begonia fimbristipulata hance, 12-21 parts of radix habenariae dentatae, 10-15 parts of folium mahoniae, 10-30 parts of stem and leaf of Japanese ardisia, and 9-18 parts of herba buddlejae lindleyanae. The traditional Chinese medicinal preparation for treating senile chronic bronchitis is small in toxic and side effects, obvious in curative effects, and treats both symptoms and root causes, and the relapse rate is low after the senile chronic bronchitis is completely treated. A preparation method of the traditional Chinese medicinal preparation for treating senile chronic bronchitis is simple, is low in cost and easy to operate, and is easy to popularize and apply.

Description

A kind of Chinese medicine preparation treating senile chronic bronchitis
Technical field
The invention belongs to Chinese medicine research and development technology field, a kind of particularly Chinese medicine treating senile chronic bronchitis Preparation.
Background technology
Chronic bronchitis is the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucous membrane and its surrounding tissue.Clinically with Cough, expectoration are cardinal symptom, continue 3 months every year, continuous 2 years or more than 2 years.The main cause that it forms is viral and thin The repeated infection of bacterium defines bronchial chronic nonspecific inflammation.When mercury dropped, respiratory tract small blood vessel spasm ischemic, prevent Imperial function reduction etc. is beneficial to cause a disease;The chronic stimulations such as smog dust, atmosphere pollution also can be fallen ill;Smoking makes bronchial spasm, sticks Film variation, ciliary movement reduction, mucilage secretion increase advantageous infectivity;Intolerance factors also have certain relation.This disease is old in being common in Year people, particularly the elderly, with the development of the state of an illness, usually concurrent obstructive emphysema, pulmonary hypertension, pulmonary heart The diseases such as disease, serious even entail dangers to patient vitals.
At present treat this sick Western medicine on medical market, such as all kinds of antibiotic etc, not only costly, therapeutic effect not Enough satisfactory, and take that too many antibiotic is harmful unhelpful, abuse of antibiotics may lead to resistance to be strengthened, Immune function of human body goes down, and causes Relapse rate difficulty to heal.
Traditional Chinese Medicine can overcome the defect that doctor trained in Western medicine is cured the symptoms, not the disease, and treats both principal and secondary aspect of disease, and effectively treats bronchitis, makes patient Break away from misery.
The information being disclosed in this background section is merely intended to increase the understanding of the general background to the present invention, and should not Recognize when being considered or imply in any form that this information structure has been the prior art well known to persons skilled in the art.
Content of the invention
The present invention treats to senile chronic bronchitis to overcome the shortcomings of present technology, open a kind of slow for old age Property bronchitis treatment have evident in efficacy, treat both principal and secondary aspect of disease, to control recurrence rate after healing low, and the less Chinese medicine preparation of toxic and side effect.
Technical scheme provided by the present invention is:
A kind of Chinese medicine preparation treating senile chronic bronchitis, is made up of following raw material by counting by weight:Pilose antler 3-9 part, tag 3-9 part, Morinda officinalis 6-10 part, fruit-rind of Chinese trichosanthes 12-18 part, seven leaf courage 15-30 parts, pimpinella thellungiana 3-9 part, amur corktree fruit 6-15 part, scattered blood 10-15 part, toothed habenaria root 12-21 part, Chinese mahonia leaf 10-15 part, Japanese ardisia 10-30 part and Lindley Butterflybush Herb 9- 18 parts.
Preferably, the Chinese medicine preparation of described treatment senile chronic bronchitis, by counting by weight by following former Material composition:7 parts of pilose antler, 6 parts of tag, 8 parts of Morinda officinalis, 15 parts of the fruit-rind of Chinese trichosanthes, 23 parts of seven leaf courage, 7 parts of pimpinella thellungiana, amur corktree fruit 13 Part, scattered 12 parts of blood, 20 parts of toothed habenaria root, 14 parts of Chinese mahonia leaf, 25 parts of the Japanese ardisia and 16 parts of Lindley Butterflybush Herb.
Present invention also offers a kind of preparation method of the Chinese medicine preparation treating senile chronic bronchitis, walk including following Suddenly:
Weigh above-mentioned each Chinese medicine material by weight, mixing is cleaned, and inserts in Traditional Chinese medicine decocting earthen pot or crock in addition to pilose antler, Add clean water, amount of water is advisable with dipped powder 3-4cm, first soaks 30-40min, then, boil with high heat before decocting, then Use slow fire instead to decoct, decoct to adding pilose antler to boil pass fire after 5min again during 180-200mL concoction for every dose, filter off the dregs of a decoction, take concoction, that is, The Chinese medicine preparation of senile chronic bronchitis must be treated.
Compared with prior art, the present invention has the advantages that:
(1) the treatment senile chronic bronchitis of the present invention Chinese medicine preparation toxic and side effect is little, evident in efficacy, sample and Control, to control recurrence rate after healing low.
(2) the Chinese medicine preparation preparation method of the treatment senile chronic bronchitis of the present invention is simple, low cost, easy to operate, Easy to spread and application.
Specific embodiment
With reference to concrete example, the present invention is further detailed explanation.The Chinese herbal medicine being previously mentioned in embodiment is by pharmacopeia Regulation medicinal part
Embodiment 1
A kind of Chinese medicine preparation treating senile chronic bronchitis, is made up of following raw material by counting by weight:Pilose antler 3g, tag 3g, Morinda officinalis 6g, fruit-rind of Chinese trichosanthes 12g, seven leaf courage 15g, pimpinella thellungiana 3g, amur corktree fruit 6g, scattered blood 10g, toothed habenaria root 12g, Chinese mahonia leaf 10g, Japanese ardisia 10g and Lindley Butterflybush Herb 9g.
Present invention also offers the preparation method of the described Chinese medicine preparation for the treatment of senile chronic bronchitis, including following Step:
Weigh above-mentioned each Chinese medicine material by weight, mixing is cleaned, and inserts in Traditional Chinese medicine decocting earthen pot or crock in addition to pilose antler, Add clean water, amount of water is advisable with dipped powder 3cm, first soaks 30min, then, boil with high heat, then use literary composition instead before decocting Fire decocts, and decocts to adding pilose antler to boil pass fire after 5min again during 180mL concoction for every dose, filters off the dregs of a decoction, take concoction, obtain final product treatment old The Chinese medicine preparation of chronic bronchitis.
Embodiment 2
A kind of Chinese medicine preparation treating senile chronic bronchitis, is made up of following raw material by counting by weight:Pilose antler 9g, tag 9g, Morinda officinalis 10g, fruit-rind of Chinese trichosanthes 18g, seven leaf courage 30g, pimpinella thellungiana 9g, amur corktree fruit 15g, scattered blood 15g, toothed habenaria root 21g, Chinese mahonia leaf 15g, Japanese ardisia 30g and Lindley Butterflybush Herb 18g.
Present invention also offers the preparation method of the described Chinese medicine preparation for the treatment of senile chronic bronchitis, including following Step:
Weigh above-mentioned each Chinese medicine material by weight, mixing is cleaned, and inserts in Traditional Chinese medicine decocting earthen pot or crock in addition to pilose antler, Add clean water, amount of water is advisable with dipped powder 4cm, first soaks 40min, then, boil with high heat, then use literary composition instead before decocting Fire decocts, and decocts to adding pilose antler to boil pass fire after 5min again during 200mL concoction for every dose, filters off the dregs of a decoction, take concoction, obtain final product treatment old The Chinese medicine preparation of chronic bronchitis.
Embodiment 3
A kind of Chinese medicine preparation treating senile chronic bronchitis, is made up of following raw material by counting by weight:Pilose antler 6g, tag 6g, Morinda officinalis 8g, fruit-rind of Chinese trichosanthes 15g, seven leaf courage 25g, pimpinella thellungiana 6g, amur corktree fruit 9g, scattered blood 12g, toothed habenaria root 16g, Chinese mahonia leaf 12g, Japanese ardisia 20g and Lindley Butterflybush Herb 15g.
Present invention also offers the preparation method of the described Chinese medicine preparation for the treatment of senile chronic bronchitis, including following Step:
Weigh above-mentioned each Chinese medicine material by weight, mixing is cleaned, and inserts in Traditional Chinese medicine decocting earthen pot or crock in addition to pilose antler, Add clean water, amount of water is advisable with dipped powder 3cm, first soaks 35min, then, boil with high heat, then use literary composition instead before decocting Fire decocts, and decocts to adding pilose antler to boil pass fire after 5min again during 200mL concoction for every dose, filters off the dregs of a decoction, take concoction, obtain final product treatment old The Chinese medicine preparation of chronic bronchitis.
Embodiment 4:The effect test of the Chinese medicine preparation of the present invention
4.1 case selection
Treat the effect of the Chinese medicine of bronchitis for the checking present invention, select the chronic bronchitis patient 400 made a definite diagnosis Clinical observation, patient is randomly divided into treatment group and two groups of control group.Treatment group 300 (be randomly divided into 3 groups, that is, treatment group 1, control Treatment group 2 and treatment group 3), the wherein male sex 150, women 150, age 46-75 year, average age 60.5 years old, course of disease 1-5; Control group 100, the wherein male sex 48, women 52, age 45-74 year, average age 59.5 years old, course of disease 1-4.
The course of disease for the treatment of group and two groups of cases of control group, degrees of symptoms are basically identical, and no significant difference has comparable Property.
4.2 medicament selection
Treatment group 1-3 takes the Chinese medicine preparation of preparation in embodiment of the present invention 1-3 respectively, takes 1 dose daily, divides early, late Take twice, took after after meal 1 hour, 16 days is 1 course for the treatment of, continuously takes 2 courses for the treatment of.
Control group uses amoxicillin sodium for injection sulbactam, drip-feed, and each 0.75g (Amoxicillin 0.5g, relaxes Batan 0.25g) -1.5 (Amoxicillin 1.0g. Sulbactam 0.5g) g, daily 3-4 time, increasing dosage can be taken the circumstances into consideration according to the state of an illness, but The daily maximum dose of Sulbactam not can exceed that 4.0g, and the course for the treatment of is depending on the state of an illness.
4.3 curative effect determinate standard
(1) cure:Persistent cough, acutely cough and the clinical symptoms such as Nausea and vomiting, chest, abdominal muscles pain All disappear, physical recovery is normal.
(2) effective:Above-mentioned symptom substantially mitigates, and body is clearly better.
(3) effective:Above-mentioned symptom has mitigated, and body has taken a turn for the better.
(4) invalid:After treatment, symptom no mitigates or increases.
4.4 results statistics (referring to table 1)
The effect test of the Chinese medicine preparation of table 1 present invention
As shown in Table 1, efficient in embodiment 1-3 is all more than 90;And cure 24 in control group, effective 14, Effective 19, invalid 40, cure rate 24%, efficient 63%.In a word, the cure rate for the treatment of group and total effective rate apparently higher than Control group.
The description of the aforementioned specific illustrative embodiment to the present invention illustrate that and illustration purpose.These descriptions It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, can much be changed And change.The purpose of selecting and describing the exemplary embodiment is that explaining that the certain principles of the present invention and its reality should With so that those skilled in the art be capable of and utilize the present invention various different exemplary and Various different selections and change.The scope of the present invention is intended to be limited by claims and its equivalents.

Claims (3)

1. a kind of Chinese medicine preparation treating senile chronic bronchitis is it is characterised in that by counting by weight by following raw material Composition:Pilose antler 3-9 part, tag 3-9 part, Morinda officinalis 6-10 part, fruit-rind of Chinese trichosanthes 12-18 part, seven leaf courage 15-30 parts, pimpinella thellungiana 3-9 Part, amur corktree fruit 6-15 part, scattered blood 10-15 part, toothed habenaria root 12-21 part, Chinese mahonia leaf 10-15 part, Japanese ardisia 10-30 part With Lindley Butterflybush Herb 9-18 part.
2. the Chinese medicine preparation for the treatment of senile chronic bronchitis according to claim 1 is it is characterised in that by by weight Number meter is made up of following raw material:7 parts of pilose antler, 6 parts of tag, 8 parts of Morinda officinalis, 15 parts of the fruit-rind of Chinese trichosanthes, 23 parts of seven leaf courage, 7 parts of pimpinella thellungiana, 13 parts of amur corktree fruit, scattered 12 parts of blood, 20 parts of toothed habenaria root, 14 parts of Chinese mahonia leaf, 25 parts of the Japanese ardisia and 16 parts of Lindley Butterflybush Herb.
3. the preparation method of the Chinese medicine preparation for the treatment of senile chronic bronchitis according to claim 1 and 2, its feature exists In comprising the following steps:
Weigh above-mentioned each Chinese medicine material by weight, mixing is cleaned, inserted in Traditional Chinese medicine decocting earthen pot or crock in addition to pilose antler, adds Clean water, amount of water is advisable with dipped powder 3-4cm, first soaks 30-40min, then, boil with high heat, then use instead before decocting Slow fire decocts, and decocts to adding pilose antler to boil pass fire after 5min again during 180-200mL concoction for every dose, filters off the dregs of a decoction, take concoction, obtain final product and control Treat the Chinese medicine preparation of senile chronic bronchitis.
CN201610869622.7A 2016-09-29 2016-09-29 Traditional Chinese medicinal preparation for treating senile chronic bronchitis Pending CN106421384A (en)

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Application Number Priority Date Filing Date Title
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102755506A (en) * 2012-06-28 2012-10-31 凌志贤 Oral traditional Chinese medicine for treating simple chronic bronchitis
CN105079479A (en) * 2015-09-01 2015-11-25 高丙军 Method for preventing silicosis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102755506A (en) * 2012-06-28 2012-10-31 凌志贤 Oral traditional Chinese medicine for treating simple chronic bronchitis
CN105079479A (en) * 2015-09-01 2015-11-25 高丙军 Method for preventing silicosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨晓海: "补肾活血化痰治疗老年慢性气管炎53例", 《甘肃中医》 *

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Application publication date: 20170222