CN106421200A - Traditional Chinese medicine composition for curing infertility - Google Patents

Traditional Chinese medicine composition for curing infertility Download PDF

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CN106421200A
CN106421200A CN201611024078.2A CN201611024078A CN106421200A CN 106421200 A CN106421200 A CN 106421200A CN 201611024078 A CN201611024078 A CN 201611024078A CN 106421200 A CN106421200 A CN 106421200A
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chinese medicine
medicine composition
extractum
radix
fructus
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CN106421200B (en
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白长川
王宝成
翁小斌
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Abstract

The invention relates to a traditional Chinese medicine composition for curing infertility. The traditional Chinese medicine composition is prepared by taking herbs of an antler tablet, human placenta, saffron crocus, a pulp of dogwood fruit, cuscuta chinensis, eucommia, morinda officinalis, fructus psoraleae, epimedium, glossy privet fruit, eclipta alba, loranthus parasiticus, angelica sinensis, parched white peony root, prepared rehmannia root,raspberry and the like as the bulk pharmaceutical chemicals.

Description

A kind of Chinese medicine composition treating infertility
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly to a kind of Chinese medicine treating infertility, it is by piece of antler, Zi He Car, Stigma Croci, Fructus Corni, Semen Cuscutae, the Cortex Eucommiae, Radix Morindae Officinaliss, Fructus Psoraleae, Herba Epimedii, Fructus Ligustri Lucidi, Herba Ecliptae, Herba Taxilli, Radix Angelicae Sinensis, The Chinese medicines such as Radix Paeoniae Alba (parched), Radix Rehmanniae Preparata, Fructus Rubi are prepared from for crude drug.
Background technology
Infertility (infertility) means that all Mr. and Mrs after marriage have normal sexual life, do not practise contraception, live together 2 years and be not subject to A kind of pregnant disease.
The method of existing treatment infertility mainly includes pharmacotherapy, and key agents have bromocriptine, Chloramiphene, urine rush property Plain (HMG), chorionic gonadotrophin (HCG), prednisone etc., Chinese medicine then has the female ball of training, spirit of preventing miscarriage etc..
In recent years, going deep into clinical research, market also the Chinese medicine preparation of some treatment infertility occurs, but existing Medicine belongs to a bit cures the symptoms, not the disease, and some use expensive composition, and some are in application process because uncertain therapeutic efficacy is cut And interrupt using.
In order to preferably excavate elite in traditional Chinese medical science department of obstetrics and gynecology ancient books, it is modern Chinese medicine department of obstetrics and gynecology clinical service, inventor's warp Obtain a kind of the kidney warming regulating menstruation and assisting pregnancy ball prescription after research for many years, the work(such as the party has warming the kidney to activate YANG, YIN nourishing adjusts blood, warm palace gravidity assisting Effect, cures mainly the blood deficiency stagnation of QI, irregular menstruation, leucorrhea with red and white discharge, cold uterus, fails to be impregnated for a long time, inadequate luteal function, adjustment estrogen and progestogen Deng disease.The present invention overcomes other prescriptions to treat the unicity of infertility type, from organic conception, with traditional Chinese medical science differential diagnosis of diseases with dialectical Based on, project and embody Clinical Treatment Thoughts Based on Syndrome Differentiation, prescription Chinese crude drug fine powder or medicinal substances extract are added suitable bonding adjuvant and makes ball Agent.
Clinic thinks, with Chinese medicine to improve estrogen and progestogen level in body, to follicle grow up and inner membrance thickness have substantially Improvement, and also have the effect of regulating menstruation induced ovulation, can increase and obtain ovum number and improve Clinical Pregnancy Rate in;The sun of the present invention rises blood The long, rule for the treatment of of regulating menstruation and assisting pregnancy, makes body reach equilibrium between yin and yang, QI and blood is smooth, function is coordinated, and can be obviously improved facing of patient Bed symptom and tcm syndrome.
Content of the invention
The present invention provides a kind of Chinese medicine composition treating infertility, and it is by the raw material of Chinese medicine medicine preparation of following weight proportion Form:
Piece of antler 0.8-1.2g, Placenta Hominiss 2.8-3.2g, Stigma Croci 0.8-1.2g, Fructus Corni 8-12g, Semen Cuscutae 23- 27g, Cortex Eucommiae 14-16g, Radix Morindae Officinaliss 14-16g, Fructus Psoraleae 14-16g, Herba Epimedii 14-16g, Fructus Ligustri Lucidi 14-16g, Herba Ecliptae 14- 16g, Herba Taxilli 18-22g, Radix Angelicae Sinensis 14-16g, Radix Paeoniae Alba (parched) 14-16g, Radix Rehmanniae Preparata 14-16g, Fructus Rubi 14-16g.
Preferably, the Chinese medicine composition of the present invention, it is prepared from by the raw material of Chinese medicine medicine of following weight proportion:
Piece of antler 1g, Placenta Hominiss 3g, Stigma Croci 1g, Fructus Corni 10g, Semen Cuscutae 25g, Cortex Eucommiae 15g, Radix Morindae Officinaliss 15g, Psoralen Fat 15g, Herba Epimedii 15g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba (parched) 15g, Radix Rehmanniae Preparata 15g, cover Basin 15g.
In composition described above, the weight of each taste medicine is to be calculated with crude drug, can increase according to corresponding proportion when producing or subtract Few, such as large-scale production can by kilogram in units of, or in units of ton, small-scale production can also with gram or milligram as list Position, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
The ratio of above weight proportion obtains through science screening, for especial patient, such as serious symptom or mild, and fat Or the patient of slight of stature, can accordingly adjust the proportioning of the amount of composition, increase or decrease less than 100%, drug effect is constant.
The Chinese medicine composition of the present invention, is through extraction or its other party by the raw material of Chinese medicine medical material forming above-mentioned formula Formula is processed, and makes pharmaceutically active substance, subsequently, with this material as raw material, adds pharmaceutically acceptable carrier, according to medicine when needing The routine techniquess of thing galenic pharmacy are made.Described active substance can be obtained it is also possible to pass through by extracting raw material of Chinese medicine respectively The common raw material of Chinese medicine medical material that extracts obtains it is also possible to obtain by other means, such as:By pulverizing, squeezing, grind, sieve, ooze Filter, extract, water extraction, alcohol extraction, ester carry, chromatograph etc. method obtain, these active substances can be extractum form material, Ke Yishi Dry extract can also be fluid extract, and different according to preparation need to determine to make different concentration.
The pharmaceutical dosage forms of the Chinese medicine composition of the present invention, preferably unit dose, can when making pharmaceutical preparation To make any pharmaceutically useful dosage form, these dosage forms are selected from:Tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule Agent, hard capsule, soft capsule, oral liquid, mouth containing agent, granule, pill, powder, unguentum, sublimed preparation, suspensoid, solution, Injection, suppository, ointment, plaster, cream, spray, patch.Preferably oral dosage form, most preferably ball Agent.
The Chinese medicine composition of the present invention, can add some pharmaceutically acceptable carriers as needed, can adopt preparation Learn routine techniquess and prepare this pharmaceutical preparation, such as pharmaceutically active substance is mixed with pharmaceutically acceptable carrier.Described medicine can connect Be subject to carrier be selected from:Mannitol, Sorbitol, sorbic acid or potassium salt, sodium pyrosulfite, sodium sulfite, sodium thiosulfate, salt Sour cysteine, TGA, Methionine, vitamin A, vitamin C, Vitamin E, vitamin D, azone, EDETATE SODIUM, EDTA Calcium sodium, the alkali-metal carbonate of monovalence, acetate, phosphate or its aqueous solution, hydrochloric acid, acetic acid, sulphuric acid, phosphoric acid, aminoacid, chlorine Change sodium, potassium chloride, sodium lactate, xylitol, maltose, glucose, Fructose, dextran, glycine, starch, sucrose, Lactose, Mannitol, silicon derivative, cellulose and its derivates, alginate, gelatin, Polyvinylpyrrolidone, glycerol, propylene glycol, second Alcohol, soil temperature 60-80, span-80, Cera Flava, lanoline, liquid paraffin, hexadecanol, gallate ester, agar, triethanolamine, Basic amino acid, carbamide, allantoin, Calcium Carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, Phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc..
The Chinese medicine composition of the present invention determines usage and dosage when using according to the situation of patient.
The Chinese medicine composition of the present invention, when making medicament, the medicament of unit dose can the pharmaceutically active containing the present invention Material 0.1-1000mg, remaining is pharmaceutically acceptable carrier.Pharmaceutically acceptable carrier can be preparation by weight The 0.1-99.9% of gross weight.
The Chinese medicine composition of the present invention, its pharmaceutically active substance is to be obtained through extracting processing, such as following processing method:
1) take Chinese crude drug, plus the decocting of 3-8 times of weight boils 1-3 time, each 1-3 hour, obtain extracting solution, filtration, concentrate To appropriate, it is prepared into extractum, with this extractum as active component, add pharmaceutically acceptable carrier when needing, according to pharmaceutical preparation The routine techniquess learned make pharmaceutical preparation.
Or
2) take Chinese crude drug, plus the decocting of 3-8 times of weight boils 1-3 time, each 1-3 hour, obtain extracting solution, filtration, concentrate To appropriate, adds ethanol to make to reach 70% concentration of alcohol, filter after standing, solution distills out ethanol, is condensed into extractum, with this Extractum is active component, adds pharmaceutically acceptable carrier, the routine techniquess according to pharmaceutics make medicine system when needing Agent.
Or
3) take Chinese crude drug, plus the alcohol reflux of the 90-95% (v/v) of 3-8 times of weight 1-3 time, each 1-3 hour, Divide and take extracting solution, filtration, solution distills out ethanol, is condensed into extractum, and with this extractum as active component, when needing, addition medicine can The carrier accepting, the routine techniquess according to pharmaceutics make pharmaceutical preparation.
The Chinese medicine composition of the present invention, side in Cornu Cervi Pantotrichum, Placenta Hominiss compatibility Semen Cuscutae etc. can the kidney warming replenishing essence, warm palace gravidity assisting;Bar Halberd sky have functions that reinforcing the kidney and supporting YANG, wind-dispelling remove, strengthening the tendons and bones, impotence and seminal emission, uterus cold infertile, menoxenia, few abdomen can be treated cold Bitterly, the card such as rheumatic arthralgia, muscles and bones impotence.Fructus Psoraleae has kidney invigorating and YANG supporting, astringent sperm contracting urine, the effect such as warming spleen and stopping diarrha, with Herba Epimedii Compatibility, strengthens the effect of Kidney-invigorating and tendon-reinforcing bone, Radix Morindae Officinaliss, Semen Cuscutae, Fructus Psoraleae compatibility can play the work of YIN nourishing Yiyang, regulating menstruation and assisting pregnancy With.Fructus Ligustri Lucidi has nourishing kidney tonifying liver, clearind deficient heat, and improving eyesight black hair etc. acts on, Herba Ecliptae enriching yin and nourishing kidney, cooling blood for hemostasis, two medicine compatibilities, The moon power of nourishing the liver and kidney strengthens, and controls the card of the hepatic and renal YIN deficiency more.It is monarch drug altogether;Fructus Rubi the kidney warming replenishing essence, joins in nourishing kidney yin medicine With yang-tonifying drug it is intended to treating YIN within YANG, make " YIN matched with sufficient YANG making living things fully vivid ";Radix Angelicae Sinensis, Radix Paeoniae Alba nourishing blood for regulating menstruation, tonifying Chong and Ren channels, with temperature Kidney Yang-strengthening drug is ministerial drug altogether;Slightly help Radix Rehmanniae Preparata, Herba Taxilli, the Cortex Eucommiae, Stigma Croci vital energy regualting and blood circulation-promoting, traffic negative and positive again.All medicines share, grows Invigorating the liver and kidney, replenishing essence blood-nourishing, tonifying Chong and Ren channels, negative and positive in balance kidney, adjust " kidney menses one rushes arbitrary born of the same parents official " Reproductive Axis, finally reach It is in harmonious proportion to " through water ", hemapodium essence is prosperous, punching times purpose smoothly, embody the traditional Chinese medical science " kidney governing reproduction ", " Tai Yunzhi road ", be really achieved Sun liter blood is long, the effect of regulating menstruation and assisting pregnancy.
Further illustrate beneficial effects of the present invention below by way of experimental data:
Case 1
【Physical data】Wang's sex:Female's age:28 the beginning of the year examined:On January 3rd, 2015
【Medical history】Main suit:Marriage unpregnancy 3 years companions menstrual period entanglement more than 2 years, excessive menstruation.7-9 after menstruation all mistakes every time My god, amount is special many, and color purple is black little clot, abdominal pain with tenesmus, dizziness, is in a cold sweat.Last menstrual period 2014.12.8
【Have a medical check-up】, arteries and veins two chi string disease greatly, pass chi all sinks weak;Yellowish fur.Doctor trained in Western medicine auxiliary examination:Gonadal hormone six carries Show:LH, P are substantially low;E2, T are substantially higher;B ultrasonic is pointed out:Uterus adnexa shows no obvious abnormalities, and Endometrium is thin, in conjunction with clinic.
【Diagnosis】, tcm diagnosis:Menoxenia, infertile, Western medicine diagnose:Abnormal uterine bleeding
【Method for the treatment of】, warming YANG and invigorating QI, regulating menstruation and assisting pregnancy
Prescription:
Piece of antler 1g, Placenta Hominiss 3g, Stigma Croci 1g, Fructus Corni 10g, Semen Cuscutae 25g, Cortex Eucommiae 15g, Radix Morindae Officinaliss 15g, Psoralen Fat 15g, Herba Epimedii 15g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba (parched) 15g, Radix Rehmanniae Preparata 15g, cover Basin 15g.
Two examine on January 10th, 2015:After medication, menstrual blood volume reduces earlier above, and color is red, and not bitterly, arteries and veins cun chi is all heavy for abdominal part, right Close heavy late, left close heavy string.
Continuously take after two months, menstruation i.e. net, normochromic on the 5th, not bitterly, headache is inconspicuous, in menstrual period the 3rd for abdomen Its six prompting " LH is slightly biased low, and remaining hormone at different levels has all recovered normal " of check gonadal hormone, top plus-minus is continuous to be treated three months, in In October, 2015 incoming all announcement is pregnant.
Case 2
Zhai, female, 34 years old.The first visit date:On August 24th, 2014.Main suit:Menstruation is delayed more than 12 years, infertile
History of present illness:The long-term menoxenia of patient, amount less, darkish complexion, have block, doctor trained in Western medicine once gave the treatment such as Progesterone and did not imitated, front Doctor was once neither imitated with the treatment such as warming the meridian and activating blood circulation, tonifying kidney and nourishing liver nourshing blood and promoting blood circulation, and 2002 because of ectopic pregnancy excision one oviductus lateraliss. Patient existing symptoms include:The menstruation amount of delaying is few, darkish complexion, fixture block, dim complexion, and fatigue is weak, fine inquiry patient's irascible temperament on ordinary days Irritability, susceptible to sorrow and being about to weep, hypochondriac pain, sighing frequently, dry mouth with bitter taste, receive food still, eating is cold and cool, lower abdomen pain fear of cold, two flanks Butt crack tenderness weakly positive, rebound tenderness is positive, soreness of waist pain, profuse leukorrhea, stool first being dry and then watery, day row 1 time, it is poor to sleep.Purplish tongue Side cusp thorn, in tongue, root thickness is greasy, deep and hesitant pulse.Estrogen level measures and reaches normal value.Because feelings will is unsuccessful before interrogating further 3 months Menstruation is caused not rise so far again again, existing waist and knee is cold, lack when the cold pain of abdomen, nocturia frequency, hyposexuality or the enuresis.Have a strong impact on trouble Person's Working Life,
Western medicine diagnose:Menoxenia, tcm diagnosis:Delayed menstrual cycle, Chinese medical discrimination:Depression of liver-QI kidney yang declines tired, the rule for the treatment of:Dredge Liver resolving depression, liver and kidney tonifying
Prescription:
Piece of antler 1g, Placenta Hominiss 3g, Stigma Croci 1g, Fructus Corni 10g, Semen Cuscutae 25g, Cortex Eucommiae 15g, Radix Morindae Officinaliss 15g, Psoralen Fat 15g, Herba Epimedii 15g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba (parched) 15g, Radix Rehmanniae Preparata 15g, cover Basin 15g.
7 pairs, it is decocted in water for oral dose, day is one, sooner or later point Winton clothes.
Two examine:The readme 7 pairs of personality that take traditional Chinese medicine are clearly better, and hypochondriac pain bitter taste cold and pain in the lower abdomen soreness of waist alleviation of pain is light, and the enuresis takes a turn for the better, band Lower amount reduces, and purplish tongue side cusp pierces, and in tongue, root thickness is greasy, deep and hesitant pulse.
Three examine:Modern patient is joyful and arrive, readme take traditional Chinese medicine the 15th secondary when menstrual onset, polychrome is dark red accompanies a large amount of blood for amount Block, rises the 3rd day and turns red through color, and patient feels refreshed, and hypochondriac pain bitter taste cold and pain in the lower abdomen soreness of waist pain is relieved, and the enuresis disappears Move back, dimly red tongue, tongue is slightly greasy in vain, deep-thready pulse.Take traditional Chinese medicine altogether 3 months with disease plus-minus afterwards, menstruation monthly comes twice again, spirit is refreshing Hurry up, Working Life recovers normal, and follow-up menstruation in 10 months connects and normally comes at the appointed time.
Case 3
Huang, female, 34 years old.Dalian government functionary.
【History of present illness】Married 7 years unpregnancies, physiology is normal on inspection for men and women.Winter in 2013, feel dizzy, weary Power, morning face swells, afternoon swelling of the feet, menses is uncomfortable.Spring in 2015, PD is serious.July 20 the same year to examine.Amenorrhea half a year, Leucorrhea is many.Soreness of the waist and knees, fear of cold, dreaminess, poor appetite, dysuria, stool is half congealed after first tying.Body of the tongue is light red, while there being indentation, tongue is white Sliding, deep-thready pulse.
【Through pregnant history】Nearly 3 years of menoxenia, on July 3 2015 last menstrual period time, does not give birth to.
【Diagnosis】Tcm diagnosis:Infertility, Western medicine diagnose:Infertility
【Method for the treatment of】Tonify Qi of the kidney, warming YANG gravidity assisting
【Prescription】
Piece of antler 1g, Placenta Hominiss 3g, Stigma Croci 1g, Fructus Corni 10g, Semen Cuscutae 25g, Cortex Eucommiae 15g, Radix Morindae Officinaliss 15g, Psoralen Fat 15g, Herba Epimedii 15g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba (parched) 15g, Radix Rehmanniae Preparata 15g, cover Basin 15g.
7 pairs, it is decocted in water for oral dose, day is one, sooner or later point Winton clothes.
【Two examine】Above clothes, anasarca significantly disappears, and appetite increases.Former side takes 15 days again.
【Three examine】Though the card such as Mental fatigue, aversion to cold take a favorable turn, passes through, taking every menstrual phase 28 days, the 10th day menstrual period after two months Detection follicle:18*19*18mm and inner membrance 9 all reach
Case 4
【Physical data】Lee, female, 27 years old, married 3 years unpregnancies.On March 10th, 2015 examines.
【Main suit】Married 3 years unpregnancies
【History of present illness】3 years unpregnancies after marriage, nearly half a year menstruation is gradually delayed, smooth less and not than before through row amount, and color is purple dark, has Clot pass through every time first 2 days first sense waist aching and tired, few abdomen tenesmus, few abdomen pain occurs immediately, the pain increased within second day through row, no Can stand, cool with extremity, it is in a cold sweat, nausea and vomiting, pale complexion, 5 days about through to the greatest extent, leucorrhea color measures many, lower abdomen in vain at ordinary times Both sides dull pain.Look into lower abdomen tenderness, on the left of lower abdomen, have streak lump.Pale tongue is dark, white and thin fur, stringy and hesitant pulse.
【Diagnosis】Tcm diagnosis:Infertility, Western medicine diagnose:Infertility
【Method for the treatment of】Blood circulation promoting and blood stasis dispelling, Chong and Ren Meridians regulating
Piece of antler 1g, Placenta Hominiss 3g, Stigma Croci 1g, Fructus Corni 10g, Semen Cuscutae 25g, Cortex Eucommiae 15g, Radix Morindae Officinaliss 15g, Psoralen Fat 15g, Herba Epimedii 15g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba (parched) 15g, Radix Rehmanniae Preparata 15g, cover Basin 15g continuously takes two months and becomes pregnant.
The present invention compares with medicine of the prior art, and advantage is as follows:
The advantage one regulating menstruation cycle
Advantage two patient thin to follicular development and endometrium has improvement
Advantage three improves Uterine Artery Blood Flow
Specific embodiment
Further illustrate the present invention by the following examples, but not as limitation of the present invention.
Embodiment 1
Piece of antler 1g, Placenta Hominiss 3g, Stigma Croci 1g, Fructus Corni 10g, Semen Cuscutae 25g, Cortex Eucommiae 15g, Radix Morindae Officinaliss 15g, Psoralen Fat 15g, Herba Epimedii 15g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba (parched) 15g, Radix Rehmanniae Preparata 15g, cover Basin 15g.
Take Chinese crude drug, plus the decocting of 5 times of weight boils 3 times, 2 hours every time, obtains extracting solution, filtration, it is concentrated into appropriate, system Standby one-tenth extractum, with this extractum as active component, adds pharmaceutically acceptable carrier, according to the conventional skill of pharmaceutics when needing Art makes pill.
Embodiment 2
Piece of antler 0.8g, Placenta Hominiss 2.8g, Stigma Croci 0.8g, Fructus Corni 8g, Semen Cuscutae 23g, Cortex Eucommiae 14g, Radix Morindae Officinaliss 14g, Fructus Psoraleae 14g, Herba Epimedii 14g, Fructus Ligustri Lucidi 14g, Herba Ecliptae 14g, Herba Taxilli 18g, Radix Angelicae Sinensis 14g, Radix Paeoniae Alba (parched) 14g, Radix Rehmanniae Preparata Yellow 14g, Fructus Rubi 14g.Take Chinese crude drug, plus the decocting of 5 times of weight boils 2 times, 2 hours every time, obtains extracting solution, filtration, concentrate To appropriate, adds ethanol to make to reach 70% concentration of alcohol, filter after standing, solution distills out ethanol, is condensed into extractum, with this Extractum is active component, adds pharmaceutically acceptable carrier, the routine techniquess according to pharmaceutics make tablet when needing.
Or
Embodiment 3
Piece of antler 1.2g, Placenta Hominiss 3.2g, Stigma Croci 1.2g, Fructus Corni 12g, Semen Cuscutae 27g, Cortex Eucommiae 16g, Radix Morindae Officinaliss 16g, Fructus Psoraleae 16g, Herba Epimedii 16g, Fructus Ligustri Lucidi 16g, Herba Ecliptae 16g, Herba Taxilli 122g, Radix Angelicae Sinensis 16g, Radix Paeoniae Alba (parched) 16g, Radix Rehmanniae Preparata Yellow 16g, Fructus Rubi 16g.
Take Chinese crude drug, plus the alcohol reflux of 95% (v/v) of 5 times of weight 2 times, 2 hours every time, point take extracting solution, Filtration, solution distills out ethanol, is condensed into extractum, with this extractum as active component, adds pharmaceutically acceptable carrier when needing, Routine techniquess according to pharmaceutics make capsule.

Claims (8)

1. a kind of Chinese medicine composition treating infertility, it is prepared from by the raw material of Chinese medicine medicine of following weight proportion:
Piece of antler 0.8-1.2g, Placenta Hominiss 2.8-3.2g, Stigma Croci 0.8-1.2g, Fructus Corni 8-12g, Semen Cuscutae 23-27g, Du Secondary 14-16g, Radix Morindae Officinaliss 14-16g, Fructus Psoraleae 14-16g, Herba Epimedii 14-16g, Fructus Ligustri Lucidi 14-16g, Herba Ecliptae 14-16g, Mulberry Parasitic 18-22g, Radix Angelicae Sinensis 14-16g, Radix Paeoniae Alba (parched) 14-16g, Radix Rehmanniae Preparata 14-16g, Fructus Rubi 14-16g.
2. Chinese medicine composition according to claim 1, it is prepared from by the raw material of Chinese medicine medicine of following weight proportion:
Piece of antler 1g, Placenta Hominiss 3g, Stigma Croci 1g, Fructus Corni 10g, Semen Cuscutae 25g, Cortex Eucommiae 15g, Radix Morindae Officinaliss 15g, Fructus Psoraleae 15g, Herba Epimedii 15g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Herba Taxilli 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba (parched) 15g, Radix Rehmanniae Preparata 15g, cover basin Sub- 15g.
3. Chinese medicine composition according to claim 1, is through carrying by the raw material of Chinese medicine medical material forming above-mentioned formula Take or other modes processing, make pharmaceutically active substance, subsequently, with this material as raw material, add pharmaceutically acceptable when needing Carrier, the routine techniquess according to pharmaceutics are made.
4. Chinese medicine composition according to claim 1, can make any pharmaceutically useful dosage form when making pharmaceutical preparation.
5. Chinese medicine composition according to claim 1, described dosage form is selected from:Tablet, capsule, oral liquid, mouth containing agent, Granule, pill, powder, unguentum, sublimed preparation, suspensoid, injection, suppository, ointment, plaster, cream, spray, patch, Drop pill.
6. the preparation method of the Chinese medicine composition described in claim 1, step is as follows:
1) take Chinese crude drug, plus the decocting of 3-8 times of weight boils 1-3 time, each 1-3 hour, obtain extracting solution, filtration, it is concentrated into suitable Amount, is prepared into extractum, with this extractum as active component, adds pharmaceutically acceptable carrier, according to pharmaceutics when needing Routine techniquess make pharmaceutical preparation.
7. the preparation method of the Chinese medicine composition described in claim 1, step is as follows:
2) take Chinese crude drug, plus the decocting of 3-8 times of weight boils 1-3 time, each 1-3 hour, obtain extracting solution, filtration, it is concentrated into suitable Amount, adds ethanol to make to reach 70% concentration of alcohol, filters, solution distills out ethanol, is condensed into extractum, with this extractum after standing For active component, when needing, add pharmaceutically acceptable carrier, the routine techniquess according to pharmaceutics make pharmaceutical preparation.
8. the preparation method of the Chinese medicine composition described in claim 1, step is as follows:
3) take Chinese crude drug, plus the alcohol reflux of the 90-95% (v/v) of 3-8 times of weight 1-3 time, each 1-3 hour, point take Extracting solution, filtration, solution distills out ethanol, is condensed into extractum, with this extractum as active component, adds medicine to be subjected to when needing Carrier, the routine techniquess according to pharmaceutics make pharmaceutical preparation.
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