CN106420787A - 一种痤疮膏及其制备方法 - Google Patents

一种痤疮膏及其制备方法 Download PDF

Info

Publication number
CN106420787A
CN106420787A CN201610786026.2A CN201610786026A CN106420787A CN 106420787 A CN106420787 A CN 106420787A CN 201610786026 A CN201610786026 A CN 201610786026A CN 106420787 A CN106420787 A CN 106420787A
Authority
CN
China
Prior art keywords
paste
acne
ointment
raw material
nepal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610786026.2A
Other languages
English (en)
Other versions
CN106420787B (zh
Inventor
陈启红
陈敏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610786026.2A priority Critical patent/CN106420787B/zh
Publication of CN106420787A publication Critical patent/CN106420787A/zh
Application granted granted Critical
Publication of CN106420787B publication Critical patent/CN106420787B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

本发明涉及一种膏剂及其制备方法,尤其涉及一种痤疮膏及其制备方法,由早用膏剂和晚用膏剂组成,早用膏剂包括第一原料和乳膏基质,晚用膏剂包括第二原料和乳膏基质,第一原料由以下物质组成:2%烟酰胺,1%水杨酸,1%克林霉素,1.5%油溶性氮酮和0.2%尼泊尔金甲酯,第二原料由以下物质组成:10%壬二酸,0.1%阿达帕林,1%克林霉素,1%水杨酸,1.5%油脂性氮酮和0.2%尼泊尔金甲酯。本发明的有益效果在于:原材料简单易得;无毒、安全;治疗效果好;制备方法简单。

Description

一种痤疮膏及其制备方法
技术领域
本发明涉及一种膏剂及其制备方法,尤其涉及一种痤疮膏及其制备方法。
背景技术
痤疮虽然大都是轻症型,说不上有什么危险,但痤疮长在脸上,又几乎都是青年人或中年人。这就会带来一些特殊问题。首先是有损美容,女性对此尤为敏感。不少需要抛头露面的行业。如外交界、新闻界、公关人员、教师、演员、歌星、运动员、导游员等,都视本病(指较重型)为大忌。对求职者来说,经常有人因此而不能通过面试关。青春痘患者本人也常自惭形秽,甚至被革职,这些人的婚恋也常受到影响。其次是有碍健康,健康当然包括心理健康,除此之外,化脓感染性损害对身体确有一定威胁。急性化脓病变可有发热、畏寒、不适、淋巴结肿大、白细胞增多等全身症状,慢性化脓性病变则可形成感染灶,对身体的影响虽较隐匿,但也更深更广。
现有技术中,CN104474090A和CN125936A等也对痤疮膏或制备痤疮膏的方法进行了研究,但仍存在不足,原材料不易得,效果不甚显著。
发明内容
本发明所要解决的技术问题是克服现有技术的不足,提出一种痤疮膏及其制备方法,其原材料简单,治疗效果好。
一种痤疮膏,由早用膏剂和晚用膏剂组成,所述的早用膏剂包括第一原料和乳膏基质,所述的晚用膏剂包括第二原料和乳膏基质。
进一步地,所述的第一原料由以下物质组成:烟酰胺,水杨酸,克林霉索,油溶性氮酮和尼泊尔金甲酯。
进一步地,所述的第一原料由以下物质组成:2%烟酰胺,1%水杨酸,1%克林霉索,1.5%油溶性氮酮和0.2%尼泊尔金甲酯。
进一步地,所述的第二原料由以下物质组成:壬二酸,阿达帕林,克林霉素,水杨酸,油脂性氮酮和尼泊尔金甲酯。
进一步地,所述的第二原料由以下物质组成:10%壬二酸,0.1%阿达帕林,1%克林霉素,1%水杨酸,1.5%油脂性氮酮和0.2%尼泊尔金甲酯。
一种制备上述痤疮膏的方法,将所述的第一原料用乳膏基质充分混合,将所述的第二原料用乳膏基质充分混合。
本发明的有益效果在于:原材料简单易得;无毒、安全;治疗效果好;制备方法简单。
具体实施方式
本申请中痤疮膏的早用膏剂,取2%烟酰胺,1%水杨酸,1%的克林霉素,1.5%油溶性氮酮和0.2%尼泊尔金甲酯,用乳膏基质充分混合。患者于早上用取少量涂于痤疮皮疹上即可。
本申请中痤疮膏的晚用膏剂,取10%壬二酸,0.1%阿达帕林,1%克林霉素,1%水杨酸,1.5%油脂性氮酮和0.2%尼泊尔金甲酯,用乳膏基质充分混合。患者于晚上用取少量涂于痤疮皮疹上即可。
以上具体实施方式仅用以说明本发明的技术方案而非限制,尽管参照实例对本发明进行了详细说明,本领域的普通技术人员应当理解,可以对本发明的技术方案进行修改或者等同替换,而不脱离本发明技术方案的精神和范围,其均应涵盖在本发明的权利要求范围当中。

Claims (6)

1.一种痤疮膏,其特征在于:由早用膏剂和晚用膏剂组成,所述的早用膏剂包括第一原料和乳膏基质,所述的晚用膏剂包括第二原料和乳膏基质。
2.如权利要求1所述的痤疮膏,其特征在于:所述的第一原料由以下物质组成:烟酰胺,水杨酸,克林霉素,油溶性氮酮和尼泊尔金甲酯。
3.如权利要求2所述的痤疮膏,其特征在于:所述的第一原料由以下物质组成:2%烟酰胺,1%水杨酸,1%克林霉素,1.5%油溶性氮酮和0.2%尼泊尔金甲酯。
4.如权利要求1所述的痤疮膏,其特征在于:所述的第二原料由以下物质组成:壬二酸,阿达帕林,克林霉素,水杨酸,油脂性氮酮和尼泊尔金甲酯。
5.如权利要求4所述的痤疮膏,其特征在于:所述的第二原料由以下物质组成:10%壬二酸,0.1%阿达帕林,1%克林霉素,1%水杨酸,1.5%油脂性氮酮和0.2%尼泊尔金甲酯。
6.一种制备如权利要求1-5中的痤疮膏的方法,其特征在于:将所述的第一原料用乳膏基质充分混合,将所述的第二原料用乳膏基质充分混合。
CN201610786026.2A 2016-08-26 2016-08-26 一种痤疮膏及其制备方法 Active CN106420787B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610786026.2A CN106420787B (zh) 2016-08-26 2016-08-26 一种痤疮膏及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610786026.2A CN106420787B (zh) 2016-08-26 2016-08-26 一种痤疮膏及其制备方法

Publications (2)

Publication Number Publication Date
CN106420787A true CN106420787A (zh) 2017-02-22
CN106420787B CN106420787B (zh) 2020-05-26

Family

ID=58090565

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610786026.2A Active CN106420787B (zh) 2016-08-26 2016-08-26 一种痤疮膏及其制备方法

Country Status (1)

Country Link
CN (1) CN106420787B (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3708152A4 (en) * 2018-07-25 2021-03-03 Chengdu Joy Young Biotechnology Co., Ltd. AZELIC ACID GEL, PROCESS OF PREPARATION AND APPLICATION

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1615152A (zh) * 2001-12-07 2005-05-11 强生消费者公司 减少痤疮或改善皮色的方法
CN102048724A (zh) * 2009-10-02 2011-05-11 强生消费者公司 用于治疗皮肤的过氧化苯甲酰组合物
CN102159216A (zh) * 2008-07-17 2011-08-17 G·莱维斯 用于痤疮治疗的方法和材料
CN102764256A (zh) * 2012-07-05 2012-11-07 渤海造船厂集团有限公司 一种治疗痤疮的药膏
WO2015114666A2 (en) * 2014-01-29 2015-08-06 Vyome Biosciences Pvt. Ltd. Treatments for resistant acne

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1615152A (zh) * 2001-12-07 2005-05-11 强生消费者公司 减少痤疮或改善皮色的方法
CN102159216A (zh) * 2008-07-17 2011-08-17 G·莱维斯 用于痤疮治疗的方法和材料
CN102048724A (zh) * 2009-10-02 2011-05-11 强生消费者公司 用于治疗皮肤的过氧化苯甲酰组合物
CN102764256A (zh) * 2012-07-05 2012-11-07 渤海造船厂集团有限公司 一种治疗痤疮的药膏
WO2015114666A2 (en) * 2014-01-29 2015-08-06 Vyome Biosciences Pvt. Ltd. Treatments for resistant acne

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3708152A4 (en) * 2018-07-25 2021-03-03 Chengdu Joy Young Biotechnology Co., Ltd. AZELIC ACID GEL, PROCESS OF PREPARATION AND APPLICATION
US11026907B2 (en) 2018-07-25 2021-06-08 Chengdu Joy Young Biotechnology Co., Ltd. Azelaic acid gel, preparation method and application thereof

Also Published As

Publication number Publication date
CN106420787B (zh) 2020-05-26

Similar Documents

Publication Publication Date Title
Coelho-de-Souza et al. Relaxant effects of the essential oil of Eucalyptus tereticornis and its main constituent 1, 8-cineole on guinea-pig tracheal smooth muscle
CN104800113B (zh) 由植物提取物、保湿剂制备的具有防腐效果的无防腐剂本草组合物及其在日用化妆品上的应用
CN102293435B (zh) 植物保健饮品
CN106420787A (zh) 一种痤疮膏及其制备方法
Li et al. An approach to the nature of Qi in TCM-Qi and bioenergy
CN104147162B (zh) 风湿止痛液及其使用方法
CN104606270A (zh) 一种含有八宝丹的药物组合物、制备方法及其用途
CN105018257B (zh) 一种抑菌止痒护肤皂及其制备方法
CN106857943A (zh) 一种保健茶
CN106551023A (zh) 一种调节血脂血压的保健茶及其加工方法
Ross Aromatic plants, spirituality, and sacred traditions II
CN104127364B (zh) 一种皮肤保健品及其制备方法
CN103519301A (zh) 一种葛根蜂蜜饮品及其制作方法
CN106821925A (zh) 元宝枫发膜配方及其使用方法
CN106421310A (zh) 一种健脑明目中药
CN106668091A (zh) 元宝枫精油配方及其使用方法
CN106728197A (zh) 一种改善便秘和腹泻的外用能量油
Mo et al. Seven-day oral intake of herbal preparation as potential stimulators for Tamm-Horsfall Protein–An ex vivo Study
CN105662994A (zh) 一种中药控油抑痘保湿水
Ahmadian et al. Effects of Aerobic exercise with spirulina supplementation on changes RBC, Hemoglobin and Hematocrit in non-athletic girls
CN108567676A (zh) 一种自制美白面膜
CN113712877A (zh) 一种烟酰胺甘菊美肤面膜液及其制备方法
CN108096164A (zh) 一种中药消肿面膜
CN104127865A (zh) 用于解酒的保健品
CN108567652A (zh) 一种自制当归活肤面膜

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
CB03 Change of inventor or designer information
CB03 Change of inventor or designer information

Inventor after: Chen Qihong

Inventor after: Zhang Li

Inventor after: Chen Yangxin

Inventor before: Chen Qihong

Inventor before: Chen Min

SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
DD01 Delivery of document by public notice
DD01 Delivery of document by public notice

Addressee: Chen Qihong

Document name: the First Notification of an Office Action

GR01 Patent grant
GR01 Patent grant