CN106420644A - Dendrobium officinale buccal tablet and preparation method thereof - Google Patents
Dendrobium officinale buccal tablet and preparation method thereof Download PDFInfo
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- CN106420644A CN106420644A CN201611031534.6A CN201611031534A CN106420644A CN 106420644 A CN106420644 A CN 106420644A CN 201611031534 A CN201611031534 A CN 201611031534A CN 106420644 A CN106420644 A CN 106420644A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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Abstract
The invention belongs to the field of food, and particularly relates to a Dendrobium officinale buccal tablet and a preparation method thereof. The Dendrobium officinale buccal tablet is prepared from the following raw materials in parts by weight: 60-80 parts of Dendrobium officinale, 10-30 parts of olive and 8-12 parts of dried orange peel. The Dendrobium officinale buccal tablet is reasonable in formula, has obvious effects on preventing and treating faucitis, gastroenteritis, angiosclerosis and the like, and does not have any toxic or side effect. The production technique is simple, and is suitable for industrial production.
Description
【Technical field】
The present invention relates to field of food is and in particular to a kind of Herba Dendrobii buccal tablet and preparation method thereof.
【Background technology】
Herba Dendrobii, also known as ferrum bracketplant, Herba hedyotis costatae, it is gained the name because epidermis is in ferrum green.Herba Dendrobii is Traditional Chinese Medicine
In a wonderful work, by common people be considered as Chinese Herba mesonae chinensis, have nourishing the stomach of promoting the production of body fluid, nourishing YIN and clearing away heat, lung moistening kidney tonifying, the strong waist of improving eyesight it
Effect.Herba Dendrobii is ancient Chinese medicine doctor, expert in health preserving is praised highly, and is considered as the good medicine that yin nourishing is empty, get rid of illness.
Modern medicine and pharmacology research shows：The main active ingredient of Herba Dendrobii be dendrobium polysaccharide, dendrobine, trace element and
Aminoacid etc., can significantly improve the immunologic function of human body, have YIN nourishing, removing toxic substances, anticancer, arteriosclerosis, expansion of blood vessels, fall blood
Pressure, resisting fatigue, radioprotective, slow down aging etc. act on, and Herba Dendrobii is even more reputation passeris montani saturati and rises in recent years, widely spreads at home and abroad.With iron sheet
Herba Dendrobii is that the relevant healthcare food of raw material all has one at aspects such as enhance immunity, antioxidation, slow down aging and cleaning throat and moistening larynx
Fixed effect；Also have certain auxiliary therapeutic action to cancer, particularly cancer patient is occurred after Radiotherapy chemotherapy thirsty,
The symptom such as dry pharynx and retch, has good curative effect.With the quickening of modern life rhythm, the increase of life stress, increasingly
Many crowds are in the sub-health state of " not having disease but unhealthy ".The health food that body function can be adjusted will necessarily play
Certain effect, becomes the new fulcrum of food service industry development.
Excavation with Herba Dendrobii effect and the development of Modern preparations technique, the health product with Herba Dendrobii as raw material
Initially enter market, form is gradually enriched, in addition to Herba Dendrobii extract, also Herba Dendrobii beverage, Herba Dendrobii crystalline substance, Herba Dendrobii
The plurality kinds of health care product such as grain.But not yet have for preventing and treating pharyngolaryngitis, gastroenteritis, sclerosis of blood vessels and other effects significantly Herba Dendrobii buccal tablet
Related product listing.
【Content of the invention】
The goal of the invention of the present invention is：For above-mentioned problem, provide a kind of Herba Dendrobii buccal tablet and its preparation
Method, described reasonable containing slice prescription, notable to preventing and treating pharyngolaryngitis, gastroenteritis, sclerosis of blood vessels and other effects, without any side effects,
Simple production process, suitable industrialized production.
To achieve these goals, the technical solution used in the present invention is as follows：
A kind of Herba Dendrobii buccal tablet, is prepared by the raw materials in：60～80 parts of Herba Dendrobii, Fructus Canarii albi 10～30
Part, 8～12 parts of Pericarpium Citri Reticulatae.
Preferably, described buccal tablet, is prepared by the raw materials in：70 parts of Herba Dendrobii, 20 parts of Fructus Canarii albi, Pericarpium Citri Reticulatae 10
Part.
A kind of method preparing Herba Dendrobii buccal tablet of the present invention, comprises the steps：
A. Fructus Canarii albi, the preparation of Pericarpium Citri Reticulatae mixed powder：Take Fructus Canarii albi, Pericarpium Citri Reticulatae, steam respectively, bakee, be ground into 200 mesh～300 mesh
Superfine powder, ratio mix homogeneously by weight, obtain mixed powder；
B. the preparation of dendrobium candidum ultrafine powder：
(1) wine is processed：Choose the raw fresh stem of Herba Dendrobii of 1-2, remove fibrous root and impurity, take its stem, with appropriate 30 °～
50 ° of rice wine mix moistening thoroughly 24 hours；
(2) bakee：With charcoal fire disk or circulating electric baking machine, the Herba Dendrobii that step (1) is obtained toasts prepared
The dry bar of Herba Dendrobii；
(3) the dry bar of Herba Dendrobii taking step (2) to be obtained, is ground into the iron sheet of 200 mesh～300 mesh using super micron mill
Dendrobe ultrafine powder, weighs up according to weight portion, standby；
C. the dendrobium candidum ultrafine powder taking step B adds in the Fructus Canarii albi of step A, Pericarpium Citri Reticulatae mixed powder, mixes, is rushed with hot water
Slurry, boils to moisture below 7%, cooling, and tabletting obtains final product product.
Further, in step A, described steaming is that medical material is placed in digester, keeps steam pressure in 0.3-
0.5MP, at 75 ± 5 DEG C, described stoving temperature is 80-100 DEG C to temperature control, and the baking time is 2-3 hour.
Further, in step C, the temperature of hot water is 80～100 DEG C.
Further, in step C, the proportioning of dendrobium candidum ultrafine powder and hot water is 25g～50g：1000ml.
Raw material effect used by the present invention is as follows：
Herba Dendrobii：Drying for orchid Herba Dendrobii Dendrobium officinale Kimura et Migo
Stem.There is nourishing YIN and clearing away heat, blood circulation promoting and blood stasis dispelling.
Fructus Canarii albi：Dry mature fruit for olive subject plant Fructus Canarii albi Canarium album Raeusch.The acid of Fructus Canarii albi sweet in the mouth,
Mild-natured, people's spleen, stomach, lung meridian, the work(having heat-clearing and toxic substances removing, sore-throat relieving resolving sputum, promoting the production of body fluid to quench thirst, relieving restlessness relieving alcoholic intoxication is it is adaptable to laryngopharynx swelling and pain, tired
Yearningly, cough expectorant blood etc..
Pericarpium Citri Reticulatae：Drying and ripening fruit for rutaceae orange Citrus reticulata Blanco and its variety
Skin.There is regulating qi-flowing for strengthening spleen, effect of drying dampness to eliminate phlegm.
In sum, due to employing technique scheme, the invention has the beneficial effects as follows：
(1) rationally, in side, Herba Dendrobii nourishing YIN and clearing away heat, the function of blood circulation promoting and blood stasis dispelling think monarch to scientific formula of the present invention；Assistant with
Fructus Canarii albi heat-clearing and toxic substances removing, sore-throat relieving resolving sputum, promoting the production of body fluid to quench thirst；Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Play nourishing YIN to relieve dryness, activating blood circulation to dissipate blood stasis, change altogether
The work(of expectorant sore-throat relieving.It is suitable for through clinical, notable to preventing and treating pharyngolaryngitis, gastroenteritis, sclerosis of blood vessels and other effects.
(2) with Herba Dendrobii punching slurry itself as binding agent, both improved the viscosity of made granule, reached no adjuvant again
Composition adds, and the active ingredient of the inventive method made buccal tablet is high compared with general technology, and nutritive value is good it is therefore prevented that other are auxiliary
Material composition reduces the probability of buccal tablet effect, avoids the harm of additive simultaneously.
(3) simple production process of the present invention, suitable industrialized production.
【Specific embodiment】
Embodiment 1
A kind of Herba Dendrobii buccal tablet of the present embodiment, is prepared by the raw materials in：60 parts of Herba Dendrobii, Fructus Canarii albi 10
Part, 8 parts of Pericarpium Citri Reticulatae.
The preparation method of the present embodiment Herba Dendrobii buccal tablet, comprises the steps：
A. Fructus Canarii albi, the preparation of Pericarpium Citri Reticulatae mixed powder：Take Fructus Canarii albi, Pericarpium Citri Reticulatae, steam respectively, bakee, be ground into 200 mesh～300 mesh
Superfine powder, ratio mix homogeneously by weight, obtain mixed powder；Wherein said steaming is that medical material is placed in digester, keeps
In 0.3-0.5MP, at 75 ± 5 DEG C, steaming time is 0.5 hour to temperature control to steam pressure；Described stoving temperature is 80-100
DEG C, the baking time is 2-3 hour；
B. the preparation of dendrobium candidum ultrafine powder：
(1) wine is processed：Choose the raw fresh stem of Herba Dendrobii of 1-2, remove fibrous root and impurity, take its stem, with appropriate 30 ° of rice
Wine mixes moistening thoroughly 24 hours；
(2) bakee：With circulating electric baking machine, it is dry that the Herba Dendrobii baking that step (1) is obtained is obtained Herba Dendrobii
Bar；
(3) take the dry bar of Herba Dendrobii that step (2) is obtained, surpassed using the Herba Dendrobii that super micron mill is ground into 200 mesh
Micropowder, weighs up according to weight portion, standby；
C. the dendrobium candidum ultrafine powder taking step B adds in the Fructus Canarii albi of step A, Pericarpium Citri Reticulatae mixed powder, mixes, with 80 DEG C of hot water
Punching slurry, the proportioning of dendrobium candidum ultrafine powder and hot water is 25g：1000ml, boils to moisture below 7%, cooling, tabletting, that is,
Obtain product.
Embodiment 2
A kind of Herba Dendrobii buccal tablet of the present embodiment, is prepared by the raw materials in：80 parts of Herba Dendrobii, Fructus Canarii albi 30
Part, 12 parts of Pericarpium Citri Reticulatae.
The preparation method of the present embodiment Herba Dendrobii buccal tablet, comprises the steps：
A. Fructus Canarii albi, the preparation of Pericarpium Citri Reticulatae mixed powder：Take Fructus Canarii albi, Pericarpium Citri Reticulatae, steam respectively, bakee, be ground into 200 mesh～300 mesh
Superfine powder, ratio mix homogeneously by weight, obtain mixed powder；Wherein said steaming is that medical material is placed in digester, keeps
In 0.3-0.5MP, at 75 ± 5 DEG C, steaming time is 45 minutes to temperature control to steam pressure；Described stoving temperature is 80-100
DEG C, the baking time is 2-3 hour；
B. the preparation of dendrobium candidum ultrafine powder：
(1) wine is processed：Choose the raw fresh stem of Herba Dendrobii of 1-2, remove fibrous root and impurity, take its stem, with appropriate 50 ° of rice
Wine mixes moistening thoroughly 24 hours；
(2) bakee：Use charcoal fire disk, the Herba Dendrobii baking that step (1) is obtained is obtained the dry bar of Herba Dendrobii；
(3) take the dry bar of Herba Dendrobii that step (2) is obtained, surpassed using the Herba Dendrobii that super micron mill is ground into 300 mesh
Micropowder, weighs up according to weight portion, standby；
C. the dendrobium candidum ultrafine powder taking step B adds in the Fructus Canarii albi of step A, Pericarpium Citri Reticulatae mixed powder, mixes, with 100 DEG C of heat
Water punching slurry, the proportioning of dendrobium candidum ultrafine powder and hot water is 40g：1000ml, boils to moisture below 7%, cooling, tabletting,
Obtain final product product.
Embodiment 3
A kind of Herba Dendrobii buccal tablet of the present embodiment, is prepared by the raw materials in：
70 parts of Herba Dendrobii, 20 parts of Fructus Canarii albi, 10 parts of Pericarpium Citri Reticulatae.
The preparation method of the present embodiment Herba Dendrobii buccal tablet, comprises the steps：
A. Fructus Canarii albi, the preparation of Pericarpium Citri Reticulatae mixed powder：Take Fructus Canarii albi, Pericarpium Citri Reticulatae, steam respectively, bakee, be ground into 200 mesh～300 mesh
Superfine powder, ratio mix homogeneously by weight, obtain mixed powder；Wherein said steaming is that medical material is placed in digester, keeps
In 0.3-0.5MP, at 75 ± 5 DEG C, steaming time is 1 hour to temperature control to steam pressure；Described stoving temperature is 80-100 DEG C,
The baking time is 2-3 hour；
B. the preparation of dendrobium candidum ultrafine powder：
(1) wine is processed：Choose the raw fresh stem of Herba Dendrobii of 1-2, remove fibrous root and impurity, take its stem, with appropriate 40 ° of rice
Wine mixes moistening thoroughly 24 hours；
(2) bakee：With circulating electric baking machine, it is dry that the Herba Dendrobii baking that step (1) is obtained is obtained Herba Dendrobii
Bar；
(3) take the dry bar of Herba Dendrobii that step (2) is obtained, surpassed using the Herba Dendrobii that super micron mill is ground into 250 mesh
Micropowder, weighs up according to weight portion, standby；
C. the dendrobium candidum ultrafine powder taking step B adds in the Fructus Canarii albi of step A, Pericarpium Citri Reticulatae mixed powder, mixes, with 90 DEG C of hot water
Punching slurry, the proportioning of dendrobium candidum ultrafine powder and hot water is 50g：1000ml, boils to moisture below 7%, cooling, tabletting, that is,
Obtain product.
Experimental example：The curative effect to pharyngolaryngitis for the Herba Dendrobii buccal tablet of the present invention
1st, physical data：
Diagnostic criteria：Pharyngeal pain, is dried uncomfortable, has foreign body sensation, burning sensation, pharyngeal mucosa diffusivity is congested.
300 patients are carried out with clinical observation treatment, age 23-58 year, the mean age is 36 years old, meets above-mentioned diagnosis mark
Accurate；300 all through upper digestive tract x-ray barivm meal fluoroscopy (screem) or fibergastroscopy no abnormality seen.
2nd, medicine：Embodiment 1～3.
3rd, Therapeutic Method：
Take the product of the present embodiment, mouth containing takes, one at a time, six times a day.It is within one month a course for the treatment of.
4th, efficacy assessment standard
Recovery from illness：Pharyngalgia, dry, scorching hot, foreign body sensation disappears, pharyngeal mucosa no substantially diffusivity hyperemia；
Take a turn for the better：Pharyngalgia, dry, scorching hot, foreign body sensation substantially mitigates, and diffusivity that pharyngeal mucosa is slight is congested；
Invalid：Pharyngalgia, dry, scorching hot, foreign body sensation no substantially mitigates, and pharyngeal mucosa is in still that diffusivity is congested.
5th, experimental result
The curative effect to treatment pharyngolaryngitis for table 1 embodiment 1～3
| Group | Recovery from illness | Take a turn for the better | Invalid | Total effective rate |
| Embodiment 1 | 65 | 34 | 1 | 99% |
| Embodiment 2 | 63 | 34 | 3 | 97% |
| Embodiment 3 | 67 | 33 | 0 | 100% |
It can be seen that present invention application clinically has significant curative effect.
Hereinafter lift several exemplary to further illustrate.
1st, open ××, 58 years old, suffer from gastroenteritis, take the buccal tablet two months of present invention making, daily 3, basic just recover
Often.
2nd, Liu's ××, 62 years old, suffers from hyperlipidemia, and sclerosis of blood vessels is often dizzy, tired, takes the buccal tablet four of present invention making
Individual month, daily 3, blood fat returned to normal, and spirit is clearly better.
Described above is the detailed description for the preferable possible embodiments of the present invention, but embodiment is not limited to this
Bright patent claim, the equal change being completed under the technical spirit suggested by all present invention or modification change, all should belong to
In the covered the scope of the claims of the present invention.
Claims (6)
1. a kind of Herba Dendrobii buccal tablet it is characterised in that：It is prepared by the raw materials in：60～80 parts of Herba Dendrobii,
10～30 parts of Fructus Canarii albi, 8～12 parts of Pericarpium Citri Reticulatae.
2. buccal tablet as claimed in claim 1 it is characterised in that：It is prepared by the raw materials in：70 parts of Herba Dendrobii,
20 parts of Fructus Canarii albi, 10 parts of Pericarpium Citri Reticulatae.
3. a kind of method preparing Herba Dendrobii buccal tablet described in claim 1 or 2 is it is characterised in that comprise the steps：
A. Fructus Canarii albi, the preparation of Pericarpium Citri Reticulatae mixed powder：Take Fructus Canarii albi, Pericarpium Citri Reticulatae, steam respectively, bakee, be ground into 200 mesh～300 purposes and surpass
Micropowder, ratio mix homogeneously by weight, obtain mixed powder；
B. the preparation of dendrobium candidum ultrafine powder：
(1) wine is processed：Choose the raw fresh stem of Herba Dendrobii of 1-2, remove fibrous root and impurity, take its stem, with appropriate 30 °～50 °
Rice wine mixes moistening thoroughly 24 hours；
(2) bakee：With charcoal fire disk or circulating electric baking machine, the prepared iron sheet of Herba Dendrobii baking that step (1) is obtained
The dry bar of Herba Dendrobii；
(3) the dry bar of Herba Dendrobii taking step (2) to be obtained, is ground into the Herba Dendrobii of 200 mesh～300 mesh using super micron mill
Superfine powder, weighs up according to weight portion, standby；
C. the dendrobium candidum ultrafine powder taking step B adds in the Fructus Canarii albi of step A, Pericarpium Citri Reticulatae mixed powder, mixes, rushes slurry with hot water, endure
Make to moisture below 7%, cooling, tabletting, obtain final product product.
4. buccal tablet as claimed in claim 3 method it is characterised in that：In step A, described steaming is that medical material is placed on digester
In, keep steam pressure in 0.3-0.5MP, at 75 ± 5 DEG C, described stoving temperature is 80-100 DEG C to temperature control, bakees the time
For 2-3 hour.
5. method as claimed in claim 3 it is characterised in that：In step C, the temperature of hot water is 80～100 DEG C.
6. method as claimed in claim 3 it is characterised in that：In step C, the proportioning of dendrobium candidum ultrafine powder and hot water is 25g
～50g：1000ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611031534.6A CN106420644A (en) | 2016-11-22 | 2016-11-22 | Dendrobium officinale buccal tablet and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611031534.6A CN106420644A (en) | 2016-11-22 | 2016-11-22 | Dendrobium officinale buccal tablet and preparation method thereof |
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| CN106420644A true CN106420644A (en) | 2017-02-22 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524234A (en) * | 2014-12-29 | 2015-04-22 | 广西玉林容山堂生物科技有限公司 | Dendrobium candidum dry strip and processing method thereof |
| CN104958567A (en) * | 2015-08-04 | 2015-10-07 | 桂林伯林生物技术有限公司 | Dendrobium candidum wall.ex lindl lozenge and preparation method thereof |
| CN105456800A (en) * | 2016-01-12 | 2016-04-06 | 陈翠玲 | Formula for treating swollen sore throat and preparing method of formula |
-
2016
- 2016-11-22 CN CN201611031534.6A patent/CN106420644A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524234A (en) * | 2014-12-29 | 2015-04-22 | 广西玉林容山堂生物科技有限公司 | Dendrobium candidum dry strip and processing method thereof |
| CN104958567A (en) * | 2015-08-04 | 2015-10-07 | 桂林伯林生物技术有限公司 | Dendrobium candidum wall.ex lindl lozenge and preparation method thereof |
| CN105456800A (en) * | 2016-01-12 | 2016-04-06 | 陈翠玲 | Formula for treating swollen sore throat and preparing method of formula |
Non-Patent Citations (1)
| Title |
|---|
| 耿鉴庭: "咽部慢性炎症防治用药备选", 《陕西新医药》 * |
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Application publication date: 20170222 |