CN106420383A - Facial cleanser and preparation method thereof - Google Patents

Facial cleanser and preparation method thereof Download PDF

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Publication number
CN106420383A
CN106420383A CN201611211843.1A CN201611211843A CN106420383A CN 106420383 A CN106420383 A CN 106420383A CN 201611211843 A CN201611211843 A CN 201611211843A CN 106420383 A CN106420383 A CN 106420383A
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CN
China
Prior art keywords
cleansing milk
aloe
weight
glycerol
emodin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611211843.1A
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Chinese (zh)
Inventor
胡波
钟勇财
谢玉国
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JIANGXI YIXINTANG MEDICAL TECHNOLOGY Co Ltd
Original Assignee
JIANGXI YIXINTANG MEDICAL TECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by JIANGXI YIXINTANG MEDICAL TECHNOLOGY Co Ltd filed Critical JIANGXI YIXINTANG MEDICAL TECHNOLOGY Co Ltd
Priority to CN201611211843.1A priority Critical patent/CN106420383A/en
Publication of CN106420383A publication Critical patent/CN106420383A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the field of cosmetics, and in particular relates to facial cleanser and a preparation method thereof. The facial cleanser is prepared from the following components by weight percent: 20-30% of a surface active agent, 1-5% of glyceryl monostearate, 10-15% of a repairing additive, 2-6% of aloe-emodin, 1-5% of chlorogenic acid, 3-7% of dipotassium glycyrrhizinate, 15-25% of glycerol, 0.1-1% of hydroxyethyl cellulose, 0.1-0.5% of essence and 5.5-47.8% of water. The facial cleanser provided by the invention not only has the functions of cleaning skin, resisting bacteria, eliminating inflammation, moisturizing and nourishing, but is also capable of repairing the skin and promoting wound healing; furthermore, the facial cleanser is safe without stimulation, thus being suitable for most people.

Description

A kind of cleansing milk and preparation method thereof
Technical field
The invention belongs to cosmetic field is and in particular to a kind of cleansing milk and preparation method thereof.
Background technology
The impaired factor of skin is varied, has extraneous physical factor, inherited genetic factorss, biological factor, health factor, doctor source Sexual factor etc..Such as, excessive ultraviolet irradiates can make skin damage, and make skin aging become coarse;Supercool, mistake Hot, excessive mechanical irritation etc. all can cause to skin to damage.And with ecological deterioration, the skin of people, or even connect maiden The physiological function of skin is also easy to impaired.At present, cleansing milk on the market is mainly used in cleaning facial dirt such as perspiration, dust Color make-up etc. is although also there is the cleansing milk of repair function, but the effect of its impaired skin of reparation is unsatisfactory.
Chinese patent CN103340806B discloses a kind of cleansing milk for repairing skin, by weight percentage, by Following components forms:Aloe extraction solution 1.2%, Herba Centellae 3%, the Radix Paeoniae Alba 4%, Semen Armeniacae Amarum 3%, Herba Violae 4%, Radix Salviae Miltiorrhizae 4%, dimension Raw element E 0.3%, Ah's glycerol 30%, stearic acid 1%, C12-13 alcohol phosphate ester potassium 0.3%, cetearyl alcohol 5%, glyceryl stearate Acid esters 2%, sodium lauryl sulfate 0.2%, sodium hydroxide 2%, oxybenzene potassium ester 0.3%, imidazolidinyl urea 0.12%, oxybenzene third Ester 0.6%, nicotiamide 0.15%, essence 0.5% and water surplus.This invention energy effective cleaning face dirt, and have whitening and The effect repaired, but its repairing performance has much room for improvement.
Chinese patent application CN105395402A discloses a kind of cleansing milk and preparation method thereof, and it is former by following weight portion Material is made:Aloe extraction solution 70-90 part, dendrobium candidum solution 40-60 part, surfactant 12-20 part, Palmic acid 6-10 part, go Ionized water 210-270 part, glycerol 8-16 part, glycol stearate 2-6 part, propylene glycol 4-10 part;Preparation method includes:Mixed Conjunction, interpolation, finished product.This cleansing milk has the effect of cleaning, moisturizing and defying age.
Content of the invention
In order to solve problems of the prior art, it is an object of the invention to provide a kind of cleansing milk and its preparation side Method.The cleansing milk that the present invention provides not only has the effect of cleaning skin, anti-inflammation, moisturizing moreover it is possible to repair skin, rush Enter the healing of wound, and the cleansing milk that the present invention provides is safe and non-stimulating, it is wide to be suitable for crowd.
The invention provides a kind of cleansing milk, including following components and its percentage by weight:
Surfactant 20-30%, glyceryl monostearate 1-5%, renovation agent 10-15%, aloe-emodin 2-6%, Chlorogenic acid 1-5%, glycyrrhizic acid dipotassium 3-7%, glycerol 15-25%, hydroxyethyl cellulose 0.1-1%, essence 0.1-0.5% and water 5.5-47.8%.
The reasonable science of compatibility of the present invention, each group split-phase interaction, work in coordination with cleaning, anti-inflammation, repair the effect of skin.
Further, described cleansing milk is made up of following components and its percentage by weight:
Surfactant 25%, glyceryl monostearate 3%, renovation agent 12.5%, aloe-emodin 4%, chlorogenic acid 3%th, glycyrrhizic acid dipotassium 5%, glycerol 20%, hydroxyethyl cellulose 0.5%, essence 0.3% and water 26.7%.Glycerol monostearate Ester CAS NO:31566-31-1, hydroxyethyl cellulose CAS NO:9004-62-0.
Further, described surfactant is by cocamido propyl betaine and alkyl polyglucoside by weight 2:3 compositions. Cocamido propyl betaine CAS NO:86438-79-1, alkyl polyglucoside is purchased from Guangzhou Jian Chuan bio tech ltd.
Further, described renovation agent is by barbaloin, Vitamin E and hesperidin by weight 2:1:2 compositions.
Meanwhile, present invention provides a kind of preparation method of cleansing milk, comprise the following steps:
S1, by water and glycerol mix homogeneously, is heated to 50-60 DEG C, and stirring adds surfactant and tristerin, Stirring, obtains solution A;
Step S1 resulting solution A is cooled to 40-50 DEG C by S2, and stirring adds renovation agent, aloe-emodin, chlorogenic acid and sweet Oxalic acid dipotassium, stirs, and obtains solution B;
Hydroxyethyl cellulose is added in step S3 resulting solution B by S3, after stirring, adds essence, stirring, obtains final product.
Aloe-emodin (C in the cleansing milk that the present invention provides15H10O5, CAS NO:481-72-1) there is antibacterial, antiinflammatory is made With;Chlorogenic acid (C16H18O9, CAS NO:327-97-9);Glycyrrhizic acid dipotassium (C42H60K2O16, CAS NO:68797-35-3) have Antiinflammatory, antiallergic, the effect of moisturizing;Barbaloin (C12H22O9, CAS NO:1415-73-2) there is bactericidal antiphlogistic, promote wound to heal The effect closed;Vitamin E (C29H50O2, CAS NO:14638-18-7);Hesperidin (C28H34O15, CAS NO:520-26-3) have There is anti-inflammation, increase ascorbic content effect.The reasonable science of compatibility of the present invention, each group split-phase interaction, work in coordination with antibacterial Antiinflammatory, the effect of reparation skin.
Compared with prior art, the cleansing milk that the present invention provides not only has cleaning skin, anti-inflammation, moisturizing Effect is moreover it is possible to repair skin, the healing of promotion wound, and the cleansing milk that the present invention provides is safe and non-stimulating, it is wide to be suitable for crowd.
Specific embodiment
Below by specific embodiment, the present invention is described in more detail, and these embodiments are only used for the purpose of illustration, It is not intended to limit protection scope of the present invention.
A kind of cleansing milk of embodiment 1
Described cleansing milk is made up of following components and its percentage by weight:
Cocamido propyl betaine 8%, alkyl polyglucoside 12%, glyceryl monostearate 1%, barbaloin 4%, vitamin E 2%, hesperidin 4%, aloe-emodin 2%, chlorogenic acid 1%, glycyrrhizic acid dipotassium 3%, glycerol 15%, hydroxyethyl cellulose 0.1%th, essence 0.1% and water 47.8%.
Preparation method:
S1, by water and glycerol mix homogeneously, is heated to 55 DEG C, stirring add cocamido propyl betaine, alkyl polyglucoside and Tristerin, stirring, obtain solution A;
Step S1 resulting solution A is cooled to 45 DEG C by S2, and stirring adds barbaloin, Vitamin E, hesperidin, Aloe Radix Et Rhizoma Rhei Element, chlorogenic acid and glycyrrhizic acid dipotassium, stir, obtain solution B;
Hydroxyethyl cellulose is added in step S3 resulting solution B by S3, after stirring, adds essence, stirring, obtains final product.
A kind of cleansing milk of embodiment 2
Described cleansing milk is made up of following components and its percentage by weight:
Cocamido propyl betaine 10%, alkyl polyglucoside 15%, glyceryl monostearate 3%, barbaloin 5%, dimension life Plain E 2.5%, hesperidin 5%, aloe-emodin 4%, chlorogenic acid 3%, glycyrrhizic acid dipotassium 5%, glycerol 20%, hydroxy ethyl fiber Element 0.5%, essence 0.3% and water 26.7%.
Preparation method is similar to Example 1.
A kind of cleansing milk of embodiment 3
Described cleansing milk is made up of following components and its percentage by weight:
Cocamido propyl betaine 12%, alkyl polyglucoside 18%, glyceryl monostearate 5%, barbaloin 6%, dimension life Plain E 3% and hesperidin 6%, aloe-emodin 6%, chlorogenic acid 5%, glycyrrhizic acid dipotassium 7%, glycerol 25%, hydroxy ethyl fiber Element 1%, essence 0.5% and water 5.5%.
Preparation method is similar to Example 1.
A kind of cleansing milk of comparative example 1
Described cleansing milk is made up of following components and its percentage by weight:
Cocamido propyl betaine 10%, alkyl polyglucoside 15%, glyceryl monostearate 3%, barbaloin 4.17%, dimension Raw element E 4.16%, hesperidin 4.17%, aloe-emodin 4%, chlorogenic acid 3%, glycyrrhizic acid dipotassium 5%, glycerol 20%, hydroxyl second Base cellulose 0.5%, essence 0.3% and water 26.7%.
Preparation method is similar to Example 1.
Difference with embodiment 2 is, the weight of barbaloin, Vitamin E and hesperidin is compared 2:1:2 replace with 1:1:1.
A kind of cleansing milk of comparative example 2
Described cleansing milk is made up of following components and its percentage by weight:
Cocamido propyl betaine 10%, alkyl polyglucoside 15%, glyceryl monostearate 3%, barbaloin 5%, dimension life Plain E 2.5%, hesperidin 5%, aloe-emodin 4%, chlorogenic acid 3%, glycyrrhizic acid dipotassium 5%, glycerol 20%, hydroxy ethyl fiber Element 0.5%, essence 0.3% and water 26.7%.
Preparation method is similar to Example 1.
Difference with embodiment 2 is, is not added with chlorogenic acid, increased the content of aloe-emodin.
Test example one, sensory evaluation test
1. test material:Embodiment 1-3 and the cleansing milk of comparative example 1-2 preparation.
2. subjects:150 people, men and women half and half, face have damage or cicatrix, 18-40 year.
3. test method:
Experimenter is randomly divided into 5 groups, every group of 30 people, it is denoted as embodiment 1-3 and comparative example 1-2 group.Each group uses respectively Cleansing milk prepared by embodiment 1-3 and comparative example 1-2, the daily morning and evening is each once, is used for situation marking and evaluates after January. Standards of grading:Using ten point system, 10 points best, and 0 point worst, and fraction more high effect is better.
4. result of the test:Analyses Methods for Sensory Evaluation Results is shown in Table 1.
Table 1 Analyses Methods for Sensory Evaluation Results
Known by table 1, the repairing effect of the cleansing milk of present invention preparation is preferable.And the repairing of cleansing milk of comparative example 1-2 preparation The effect of the cleansing milk that multiple effect is prepared than embodiment 1-3 is poor, and the reasonable science of compatibility of the present invention is described, each group split-phase interaction is assisted With the effect playing reparation.Meanwhile, the cleansing milk of present invention preparation also has cleaning, the effect of moisturizing antiinflammatory.
Test example two, antibacterial tests
1. test material:Embodiment 1-3 and the cleansing milk of comparative example 1-2 preparation.
2. subjects:Staphylococcus aureuses ATCC6538, Candida albicans ATCC10231, bacillus pyocyaneus ATCC15442.
3. content of the test:
Evaluate according to industry standard QB/T2738-2005 daily chemical products antibacterial bacteriostatic effect, carry out antibacterial effect test, real The activity applying the cleansing milk of a 1-3 and the preparation of comparative example 1-2 is 1wt%, is action time 20 minutes, record sterilization Rate.
4. result of the test:Antibacterial effect test result is shown in Table 2.
Table 2 antibacterial effect test result
As shown in Table 2, the cleansing milk of present invention preparation has preferable antibacterial effect.And comparative example 1-2 preparation wash one's face The effect of the cleansing milk that the antibacterial effect of milk is prepared than embodiment 1-3 is poor, illustrate compatibility of the present invention rationally, science, and each component Mutually work in coordination with the effect of antibacterial, simultaneously in the case of anti-inflammation, improve the repair function of skin.

Claims (5)

1. a kind of cleansing milk is it is characterised in that include following components and its percentage by weight:
Surfactant 20-30%, glyceryl monostearate 1-5%, renovation agent 10-15%, aloe-emodin 2-6%, green former Sour 1-5%, glycyrrhizic acid dipotassium 3-7%, glycerol 15-25%, hydroxyethyl cellulose 0.1-1%, essence 0.1-0.5% and water 5.5- 47.8%.
2. cleansing milk as claimed in claim 1 is it is characterised in that be made up of following components and its percentage by weight:Live in surface Property agent 25%, glyceryl monostearate 3%, renovation agent 12.5%, aloe-emodin 4%, chlorogenic acid 3%, glycyrrhizic acid dipotassium 5%th, glycerol 20%, hydroxyethyl cellulose 0.5%, essence 0.3% and water 26.7%.
3. cleansing milk as claimed in claim 1 or 2 is it is characterised in that described surfactant is by cocamidopropyl propyl amide Radix Betae Alkali and alkyl polyglucoside by weight 2:3 compositions.
4. cleansing milk as claimed in claim 1 or 2 is it is characterised in that described renovation agent is by barbaloin, Vitamin E and Pericarpium Citri junoriss Glycoside by weight 2:1:2 compositions.
5. the preparation method of described cleansing milk as arbitrary in claim 1-4 is it is characterised in that comprise the following steps:
S1, by water and glycerol mix homogeneously, is heated to 50-60 DEG C, and stirring adds surfactant and tristerin, stirs, Obtain solution A;
Step S1 resulting solution A is cooled to 40-50 DEG C by S2, and stirring adds renovation agent, aloe-emodin, chlorogenic acid and glycyrrhizic acid Dipotassium, stirs, and obtains solution B;
Hydroxyethyl cellulose is added in step S3 resulting solution B by S3, after stirring, adds essence, stirring, obtains final product.
CN201611211843.1A 2016-12-25 2016-12-25 Facial cleanser and preparation method thereof Pending CN106420383A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201611211843.1A CN106420383A (en) 2016-12-25 2016-12-25 Facial cleanser and preparation method thereof

Publications (1)

Publication Number Publication Date
CN106420383A true CN106420383A (en) 2017-02-22

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108420777A (en) * 2018-06-07 2018-08-21 深圳市安德堂生物科技有限公司 A kind of facial cleanser and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306229A (en) * 2014-09-30 2015-01-28 青岛叁鼎卫生制品有限公司 Aloe moisturizing facial cleanser
CN104887589A (en) * 2015-06-23 2015-09-09 中国热带农业科学院农产品加工研究所 Whitening and moisturizing body cream and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306229A (en) * 2014-09-30 2015-01-28 青岛叁鼎卫生制品有限公司 Aloe moisturizing facial cleanser
CN104887589A (en) * 2015-06-23 2015-09-09 中国热带农业科学院农产品加工研究所 Whitening and moisturizing body cream and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张国山: "《中药及其临床》", 31 December 1991, 中国医药科技出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108420777A (en) * 2018-06-07 2018-08-21 深圳市安德堂生物科技有限公司 A kind of facial cleanser and preparation method thereof

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