CN106418528A - Health food for functional uterine bleeding patients and preparation method of health food - Google Patents
Health food for functional uterine bleeding patients and preparation method of health food Download PDFInfo
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Abstract
The invention relates to health food for functional uterine bleeding patients and a preparation method of the health food, and belongs to the technical field of functional foods. The health food comprises food materials and traditional Chinese medicinal materials, the food materials comprise millet, potatoes, sweet potatoes, lotus root starch and black sesame, and the traditional Chinese medicinal materials comprise Chinese yam, cattail pollen, red-rooted salvia roots, Himalayan teasel roots, wormwoodlike motherwort herb, cuttle bones, Chinese angelica roots, prepared rehmannia roots, nutgrass galingale rhizome, Chinese waxgourd seeds, barbary wolfberry fruits, palmleaf raspberry fruits, safflower flowers, Mongolian milkvetch roots, ass-hide gelatin and ural licorice roots. The health food has simultaneously supplying advantages of medicine and food, no toxic and side effects of medicines and health care and adjuvant therapy effects of both principal and secondary aspects of diseases, can regulate and nourish from roots of the diseases and is suitable for taking for a long time. The health food is low in cost and process difficulty, good in effect, suitable for people of all ages, popularization and application and easily transformed into mass production.
Description
Technical field
The present invention relates to edible health food of a kind of confession functional uterine bleeding and preparation method thereof, belongs to function
Property food technology field.
Background technology
Medicated diet rise in the traditional diet of China and the dietary therapy of Chinese medicine culture, medicated diet be in Chinese medicine, cookery and threpsology
Under theoretical direction, medicated food formula is strictly pressed, will be compatible with some foods with medical value for Chinese medicine, using China's uniqueness
The ticbit with certain color, shape that diet culinary art and modern scientific method are made.It is Chinese biography
The product that the medical knowledge of system is combined with cooking experience.Its " residence is cured in food ", both using medicine as food, and food is assigned to
Medicinal, food power borrowed by medicine, and food helps medicine prestige, and the two complements each other, and brings out the best in each other;Both there is higher nutritive value, and preventable disease had been controlled
Disease, health body-building, life lengthening.
Dysfunctional uterine hemorrhage, the menstruation for causing mainly due to nervous system and hormonal system functional disorder is not just
Often.Clinical manifestation is irregular metrorrhagia, the confusion of the menstrual cycle, and prolonged bleeding time is many through blood volume, or even bleeds profusely
Or it is dripping more than.
The dysfunctional uterine hemorrhage traditional Chinese medical science is also referred to as metrorrhagia, when referring to that menses are non-cruelly under more than or dripping the former claims metrorrhagia not to the utmost,
Under the latter's steelyard slepsydra.The etiology and pathogenesis of metrorrhagia are mainly void(Kidney deficiency, insufficiency of the spleen)Heat, the stasis of blood are evil to damage punching times, it is impossible to restrict menses, so that
Absurd row when menses are non-.As metrorrhagia is lost blood gas consumption, with the passing of time the course of disease, causes QI and blood, deficiency in both YIN and YANG.And metrorrhagia is with the passing of time, blood circulating out of vessels
For blood stasis.Therefore the normal reciprocal causation of the generation of primary disease, QI and blood being ill simultaneously, how dirty involvement, deficiency syndrome mingling with excess syndrome.
The traditional Chinese medical science is divided into five types dysfunctional uterine bleeding.
(1)Excess-heat:Cycle disorder, many or dripping unnet through blood volume, the dark red matter of color is adjusted, flushing thirsty, constipation with dry stool, red tongue tongue
Yellow or yellow greasy, full and rapid pulse.Control suitable clearing away heat and cooling blood, blood-arresting catamenia-regulating.
(2)Deficiency-heat:The confusion of the menstrual cycle, amount is many or few, and dripping unnet, the scarlet matter of color is thick, vexed hectic fever, Shou Zuxin
Heat, red urine stool dry, the few hardship of red tongue, thready and rapid pulse.Control suitable nourishing YIN and clearing away heat, cooling blood for hemostasis, regulating menstruation.
(3)Deficiency of kidney-QI:The confusion of the menstrual cycle, amount is many or dripping more than, and color talks matter clearly, aversion to cold and cold limbs, dim complexion, waist-leg
Aching and limp, pale tongue white and thin fur, deep-thready pulse.Control suitable the kidney invigorating Gu Chong, blood-arresting catamenia-regulating.
(4)Insufficiency of the spleen:The confusion of the menstrual cycle, metrorrhagia or dripping, color is light, and matter is dilute, with the lazy speech of shortness of breath, spiritlessness and weakness, complexion
Fructus Persicae is white, or puffiness of the face and limbs, and two lower limbs are aching and limp, or carefully lacks loose stool, pale tongue white and thin fur, weak pulse.Control suitable nourishing qi to stop, nourishing blood for regulating menstruation.
(5)Blood stasis:The confusion of the menstrual cycle, menses at present when stop, or dripping net, color purple black have block, little abdominal distention or pain, body of the tongue
Purple dark or petechiae, white and thin fur, hesitant pulse or string.Control suitable activating blood circulation to dissipate blood stasis, blood-arresting catamenia-regulating.
Content of the invention
The technical problem to be solved in the present invention is a kind of a kind of edible health care food of confession functional uterine bleeding of invention
Product, make the food have the effect of preferable health-care effect and auxiliary treatment.For solving the technical problem, the technical side of inventor
Case is, according to traditional Chinese medicine theory and nutritional knowledge *, meticulous compatibility medical material and food materials, makes the two possess the special patients
While required abundant nutrition, possesses the effect of good health care and auxiliary treatment.Inventor through test repeatedly and practice,
A kind of health-care effect significant functional food has finally been invented, and the formula of the food is expressed as with weight portion:
Semen setariae 20-80 part, Rhizoma Solani tuber osi 7-30 part, Radix Ipomoeae 7-30 part, Amylum Nelumbinis Rhizomatis 1-15 part, Semen Sesami Nigrum 1-9 part, Chinese medicine extract 2-15
Part;
Chinese medicine extract:Rhizoma Dioscoreae 9-30 part, Pollen Typhae 8-28 part, Radix Salviae Miltiorrhizae 6-19 part, Radix Dipsaci 4-13 part, Herba Leonuri 6-19 part, sea Piao
Octopus ocellatus Gray 7-25 part, Radix Angelicae Sinensis 8-28 part, Radix Rehmanniae Preparata 4-16 part, Rhizoma Cyperi 5-17 part, Semen Benincasae 8-27 part, Fructus Lycii 6-18 part, Fructus Rubi 4-
12 parts, Flos Carthami 4-13 part, Radix Astragali 5-16 part, Colla Corii Asini 6-20 part, Radix Glycyrrhizae 5-13 part.
The formulation ratio with excellent health-care effect in practice process preferably out is expressed as with weight portion:
40 parts of Semen setariae, 15 parts of Rhizoma Solani tuber osi, 13 parts of Radix Ipomoeae, 7 parts of Amylum Nelumbinis Rhizomatis, 4 parts of Semen Sesami Nigrum, 8 parts of Chinese medicine extract;
Chinese medicine extract:19 parts of Rhizoma Dioscoreae, 18 parts of Pollen Typhae, 12 parts of Radix Salviae Miltiorrhizae, 8 parts of Radix Dipsaci, 13 parts of Herba Leonuri, 15 parts of Endoconcha Sepiae, Radix Angelicae Sinensis
15 parts, 9 parts of Radix Rehmanniae Preparata, 11 parts of Rhizoma Cyperi, 18 parts of Semen Benincasae, 11 parts of Fructus Lycii, 7 parts of Fructus Rubi, 8 parts of Flos Carthami, 10 parts of the Radix Astragali, Colla Corii Asini 12
Part, 9 parts of Radix Glycyrrhizae.
The present invention discloses a kind of preparation method of the health food of confession functional type metrorrhagia edible for patients, including following step
Suddenly:
(1)Chinese medicine extract in formula used by Chinese crude drug is accurately weighed;
(2)By the Colla Corii Asini distilled water molten of 5-12 times of weight, standby;
(3)By Rhizoma Dioscoreae, Pollen Typhae, Radix Salviae Miltiorrhizae, Radix Dipsaci, Herba Leonuri, Endoconcha Sepiae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Cyperi, Semen Benincasae, Fructus Lycii, cover basin
Son, Flos Carthami, the Radix Astragali, Radix Glycyrrhizae, add the distilled water of initial 7-17 times of weight of medical material, soak 4-24 hour, and it is little that backflow decocts 1-6
When, to filter, the distilled water of 4-11 times of weight of initial weight is added, backflow decocts 1-5 hour, filters and retain filtering residue, merges
Filtrate, the concentrated solution for being concentrated into 60 DEG C of relative densities for 1.10-1.14 is standby;
(4)By step(3)Filtering residue add 5-12 times of weight concentration 55-85% ethanol, reflux, extract, 2 times, each 1-6 hour,
Filter, merging filtrate, vacuum distillation removes ethanol, and it is standby for the concentrated solution of 1.10-1.14 to be concentrated into 60 DEG C of relative densities;
(5)By the Colla Corii Asini of molten and step(3)With(4)The concentrated solution of gained merges, mix homogeneously, continues to be concentrated into 60 DEG C relatively
Density is the concentrated liquid of tradition Chinese medicine of 1.18-1.23, and as Chinese medicine extract, standby;
(6)Semen setariae, Rhizoma Solani tuber osi, Radix Ipomoeae, Amylum Nelumbinis Rhizomatis, Semen Sesami Nigrum, Chinese medicine extract are accurately weighed;
(7)Rhizoma Solani tuber osi, Radix Ipomoeae are cleaned, peeling, stripping and slicing, plus 1-5 times of decocting in water 10-60 minute, smash to pieces, homogenizing, mistake 40-80
Mesh sieve, obtains mixed soil, standby;
(8)Semen Sesami Nigrum is crushed and is mixed homogeneously with Semen setariae, plus 5-18 times of water, 15-60 minute is boiled, by step(6)Chinese medicine
Extract and step(7)Mixed soil add mix, be subsequently adding Amylum Nelumbinis Rhizomatis, heat while stirring, continue after mixing to boil 2-20
Minute, cooling is raw material health product;
(9)Raw material health product can be added appropriate adjuvant, such as sucrose, Mel, sweetener, Sal, essence, vegetable, pigment
Deng adjuvant, using modern general processing and packing technique, health food is made.
Further, the health food can be made to be convenient for carrying to open and fill instant pop can, plastics packed liquid
Medicated porridge.Can also will be homogeneous further for raw material health product, or be spray-dried, or lyophilization, make the packed nutrition for easily brewing
Powder.
The nutritional labeling of health food raw materials of the present invention and special efficacy:
Semen setariae:Semen setariae is also known as Semen setariae, and Gu claims foxtail millet, cries fine strain of millet again, be one of ancient Chinese " grain rice ", and the master that northerner likes
Want one of grain.Semen setariae contains protein, higher than rice.1.7 grams of fat, 76.1 grams of carbohydrate, all it is not less than paddy and wheat.One
As the carotene that do not contain in grain, Semen setariae reaches 0.12 milligram per 100 grams of contents, vitamin B1Content occupy all grains
First of.Semen setariae is because being rich in vitamin B1、B12Deng giving birth to skin ulcer have functions that dyspepsia and bicker is prevented;Semen setariae has to be prevented instead
Stomach, effect of vomiting;Semen setariae also has the function of nourishing YIN and benefiting blood, is taken good care of can the body constitution of puerpera's deficiency and coldness, help them
Regain one's strength;Semen setariae has mitigation wrinkle, mottle, pigmented effect.
Rhizoma Solani tuber osi:Ingredient in general fresh potato:Starch 9-20%, protein 1.5-2.3%, fatty 0.1-
1.1%, crude fibre 0.6-0.8%.Contained nutritional labeling in 100g Rhizoma Solani tuber osi:318 kilojoule of energy, calcium 5-8mg, phosphorus 15-40mg,
Ferrum 0.4mg-0.8mg, potassium 200-340mg, iodine 0.8-1.2, carotene 12-30mg, thiamine 0.03-0.08mg, riboflavin
0.01-0.04mg, nicotinic acid 0.4-1.1mg.The traditional Chinese medical science think Rhizoma Solani tuber osi " flat property and sweet taste is nontoxic, can invigorating the spleen and regulating the stomach, QI invigorating adjust in,
Relieving spasm to stop pain, tonneau is defecated.Weakness of the spleen and stomach, dyspepsia, the intestines and stomach discord, gastral cavity abdomen are had a pain, the not smooth patient outcome that defecates shows
Write ".Modern study is proved, Rhizoma Solani tuber osi has specially good effect to reconciling dyspepsia, is good medicine and the high-quality guarantor of gastropathy and cardiac
Strong product.Rhizoma Solani tuber osi is being rich in nutrition, is one of food of defying age.
Radix Ipomoeae:Radix Ipomoeae rich in proteins, starch, pectin, cellulose, aminoacid, vitamin and several mineral materials, have " long
The reputation of longevity food ".Sugar content reaches 15%-20%.There is the effects such as anticancer, cardioprotection, prevention emphysema, diabetes, fat-reducing.Bright
For Li Shizhen (1518-1593 A.D.)《Compendium of Materia Medica》Note has " Rhizoma Dioscoreae esculentae qi-restoratives, spleen benefiting and stimulating the appetite, kidney tonifying the moon ", and says the longevity of marine people's food.The traditional Chinese medical science is regarded
Radix Ipomoeae is good medicine.
Amylum Nelumbinis Rhizomatis:Amylum Nelumbinis Rhizomatis contain calcium, ferrum, phosphorus and multivitamin in addition to starch-containing, glucose, protein, also.The traditional Chinese medical science thinks
Rhizoma Nelumbinis energy tonifying five ZANG-organses, and taste, Buqi Yangxue.Raw Rhizoma Nelumbinis nature and flavor are sweet cool, and after being processed into Amylum Nelumbinis Rhizomatis, its property is both easy to disappear also by cool alternating temperature
Change, have the effect of replenishing body fluid and clearing away heat pathogen, nourishing the stomach YIN nourishing, invigorating the spleen and benefiting QI, nourishing blood and hemoslasis again.Amylum Nelumbinis Rhizomatis are also the work for helping for sleep well
Tool, Amylum Nelumbinis Rhizomatis have the effects such as heat clearing away, blood-nourishing, relieving restlessness, can control blood deficiency insomnia.A little bowl is brewed before sleeping, and there have after having drunk to be very good
Sleep of calming the nerves effect.
Semen Sesami Nigrum:Semen Sesami Nigrum is the black seeds of Pedaliaceae Semen Sesami, containing substantial amounts of fat and protein, also containing sugar
The nutritional labelings such as class, VitAVitE, lecithin, calcium, ferrum, chromium.There are stomach invigorating, liver protection, the work of promotion red blood cell growth
With while internal melanin can be increased, being conducive to natural on-off cycles of hair growth.Semen Sesami Nigrum medicine-food two-purpose, with " the five internal organs, benefit are grown in invigorating the liver and kidney
Essence and blood, intestine moistening is dry " etc. health-care effect, be considered to nourish holy product.On the one hand it is because containing high quality protein and abundant mineral
Matter, is on the other hand because containing abundant unsaturated fatty acid, the sesamin of vitamin E and preciousness and melanin.
Rhizoma Dioscoreae:This product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Sweet in the mouth, mild-natured;Returns spleen, lung, kidney channel;Spleen reinforcing nourishing the stomach,
Engender liquid and benefic lung, the kidney invigorating arresting seminal emission.
Pollen Typhae:This product is the dry pollen of the turbid Herba Typhae of Typhaceae vegetation water, typha orientalises or congener.Sweet in the mouth, mild-natured;
Return liver, pericardium channel;Hemostasis, blood stasis dispelling, treating stranguria.
Radix Salviae Miltiorrhizae:This product dries root and rhizome for labiate Radix Salviae Miltiorrhizae.Bitter in the mouth, cold nature;GUIXIN, Liver Channel;Blood stasis dispelling stops
Bitterly, promoting blood circulation to restore menstrual flow, relieving restlessness that clears away heart-fire.
Radix Dipsaci:This product is the dry root of Dipsacaceae plant Radix Dipsaci.Bitter in the mouth, pungent, slightly warm in nature;Return liver and kidney channel;Tonifying liver
Kidney, bone and muscle strengthening, continuous injured, only metrorrhagia.
Herba Leonuri:This product is the fresh or dry aerial parts of labiate Herba Leonuri.Bitter in the mouth, pungent, cold nature;Return
Liver, pericardium channel;Promoting blood flow to regulate menstruation, inducing diuresis to remove edema.
Endoconcha Sepiae:This product be Sepiidae animal sepiella maindroni de Rochebrune or golden cuttlefish dry inner shell.Salty in the mouth, puckery, warm in nature;Returns spleen,
Kidney channel;Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.
Radix Angelicae Sinensis:This product is the dry root of umbelliferae angelica.Sweet in the mouth, pungent, warm in nature;Return liver, the heart, spleen channel;Replenishing and activating blood,
Menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Radix Rehmanniae Preparata:This product is the Preparation process product of Radix Rehmanniae.Sweet in the mouth, slightly warm in nature;Return liver and kidney channel;Nourishing YIN and supplementing blood, beneficial essence is filled out
Marrow.
Rhizoma Cyperi:This product is the dry rhizome of sedge dried tuber.Acrid in the mouth, slight bitter, micro-sweet, mild-natured;Return liver, spleen, three Jiao
Warp;Promoting QI circulation for relieving depression, menstruction regulating and pain relieving.
Semen Benincasae:That is the dry mature seed of Fructus Benincasae.Sweet in the mouth;Cold nature;Return lung;Large intestine channel;Removing heat from the lung and dissipating phlegm;Eliminating carbuncle is arranged
Pus;Dampness removing.
Fructus Lycii:This product is the dry mature fruit of plant of Solanaceae lycium barbarum.Sweet in the mouth, mild-natured;Return liver and kidney channel;Nourishing
Liver and kidney, replenishing vital essence to improve eyesight.
Fructus Rubi:This product is the dry fruit of rose family rubus plant rubus chingii Hu.Sweet in the mouth, acid, warm in nature;Return
Kidney, bladder warp;Kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination.
Flos Carthami:Another name red blue flower, thorn safflower, Compositae, Flos Carthami platymiscium.Acrid in the mouth, warm in nature;Enter the heart, Liver Channel;Promoting blood circulation to restore menstrual flow,
Blood stasis removing pain relieving.
The Radix Astragali:This product is the dry root of leguminous plant Radix Astagali or Radix Astragali.Sweet in the mouth, warm in nature;Return lung, spleen channel;Mend
Superficies-consolidating, diuretic and maintain drug, evacuation of pus, expelling pus and promoting granulation.
Colla Corii Asini:This product is the skin of equine speciess donkey through decocting, concentrating the solid gum that makes.Sweet in the mouth, mild-natured;Return lung, liver, kidney
Warp;Enrich blood YIN nourishing, moisturize, hemostasis.
Radix Glycyrrhizae:This product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Sweet in the mouth, mild-natured;GUIXIN, lung,
Spleen, stomach;Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The formulation analysis of health food of the present invention:
Anovulatory dysfunctional uterine hemorrhage is common gynecological disease, and the traditional Chinese medical science thinks that the etiology and pathogenesis of metrorrhagia are mainly void(Kidney deficiency, insufficiency of the spleen)Heat, the stasis of blood
Evil damage punching is appointed, it is impossible to restrict menses, so that absurd row when menses are non-.Chinese medical discrimination can be divided into:Heat in blood bleeding, cold womb bleeding, blood
Empty bleeding, blood stasis bleeding, deficiency of vital energy bleeding.Control suitable clearing away heat and cooling blood, blood-arresting catamenia-regulating, nourishing YIN and clearing away heat, the kidney invigorating Gu Chong, nourishing blood for regulating menstruation, work
Blood blood stasis dispelling.
Pollen Typhae, Endoconcha Sepiae in inventive formulation has anastaltic effect;Radix Salviae Miltiorrhizae, Radix Dipsaci, Radix Angelicae Sinensis, Herba Leonuri have
Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, The strong bone of kidney tonifying, effect of promoting blood flow to regulate menstruation;Rhizoma Dioscoreae, Radix Rehmanniae Preparata, Rhizoma Cyperi, the Radix Astragali have nourishing YIN and supplementing blood, benefit
The effects such as essence is filled out marrow, the kidney invigorating and is rushed admittedly;Semen Benincasae, Fructus Lycii, Fructus Rubi, Flos Carthami, Colla Corii Asini have nourishing YIN and clearing away heat, YIN nourishing of enriching blood, go
The effects such as stasis of blood pain relieving, kidney tonifying dampness removing, Radix Glycyrrhizae can make all medicine negative and positive together, the exterior and the interior mutual assistance with coordinating the actions of various ingredients in a prescription.Additionally, the present invention
Semen setariae, Rhizoma Solani tuber osi, Radix Ipomoeae, Amylum Nelumbinis Rhizomatis, Semen Sesami Nigrum in formula is necessary in fat, albumen, saccharide etc. necessary to offer human body
Outside nutrient substance, also have nourishing YIN and benefiting blood, invigorating the spleen and regulating the stomach, qi-restoratives kidney tonifying, nourishing blood and hemoslasis, nourishing the liver and kidney the effects such as.These food
Raw material and the collocation of Chinese crude drug science, complement each other in effect, bring out the best in each other, so as to reach good health care and auxiliary treatment
Effect.
Compared with prior art, health food of the present invention has medicine food with the advantage that mends, suitable long-term consumption, no medicine
Toxic and side effects, can start with from the root of disease carries out conditioning nourishing, and the health care and auxiliary so as to have giving consideration to both the incidental and fundamental to disease is controlled
Therapeutic effect;Additionally, health food low cost of the present invention, effect are good, technology difficulty is little, suit the taste of both old and young, be easy to conversion large-scale production,
Suitable popularization and application.
Specific embodiment
Embodiment 1
With grope in the arbitrary value in the range of Ricipe for health care food of the present invention and practice process optimal processing parameter production packed
Nutritive powder.
(1)Each taste Chinese crude drug in formula is accurately weighed:Rhizoma Dioscoreae 900g, Pollen Typhae 2800g, Radix Salviae Miltiorrhizae 1700g, Radix Dipsaci 500g,
Herba Leonuri 1800g, Endoconcha Sepiae 800g, Radix Angelicae Sinensis 2700g, Radix Rehmanniae Preparata 500g, Rhizoma Cyperi 600g, Semen Benincasae 2600g, Fructus Lycii 1800g, cover
Basin 400g, Flos Carthami 1300g, Radix Astragali 1100g, Colla Corii Asini 1500g, Radix Glycyrrhizae 600g;
(2)By the Colla Corii Asini distilled water molten of 9 times of weight, standby;
(3)By Rhizoma Dioscoreae, Pollen Typhae, Radix Salviae Miltiorrhizae, Radix Dipsaci, Herba Leonuri, Endoconcha Sepiae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Cyperi, Semen Benincasae, Fructus Lycii, cover basin
Son, Flos Carthami, the Radix Astragali, Radix Glycyrrhizae, add the distilled water of initial 12 times of weight of medical material, soak 8 hours, and backflow is decocted 3 hours, filter,
Add the distilled water of 7 times of weight of initial weight, backflow is decocted 2 hours, filter and retain filtering residue, merging filtrate, it is concentrated into 60
DEG C relative density is standby for the concentrated solution of 1.10-1.14;
(4)By step(3)Filtering residue add 7 times of weight concentration 55-85% ethanol, reflux, extract, 2 times, 2 hours every time, filter,
Merging filtrate, vacuum distillation removes ethanol, and it is standby for the concentrated solution of 1.10-1.14 to be concentrated into 60 DEG C of relative densities;
(5)By the Colla Corii Asini of molten and step(3)With(4)The concentrated solution of gained merges, mix homogeneously, continues to be concentrated into 60 DEG C relatively
Density is the concentrated liquid of tradition Chinese medicine of 1.18-1.23, and as Chinese medicine extract, standby;
(6)Semen setariae 2000g, Rhizoma Solani tuber osi 3000g, Radix Ipomoeae 700g, Amylum Nelumbinis Rhizomatis 1500g, Semen Sesami Nigrum 100g, Chinese medicine extract are accurately weighed
1500g;
(7)Rhizoma Solani tuber osi, Radix Ipomoeae are cleaned, peeling, stripping and slicing, plus 3 times of decocting in water system 30 minutes, smash to pieces, homogenizing, cross 50 mesh sieves, obtain
Mixed soil, standby;
(8)Semen Sesami Nigrum is crushed and is mixed homogeneously with Semen setariae, plus 12 times of water, boil 20 minutes, by step(6)Chinese medicine extract
And step(7)Mixed soil add mix, be subsequently adding Amylum Nelumbinis Rhizomatis, heat while stirring, continue after mixing to boil 5 minutes, cooling
As raw material health product;
(9)Raw material health product are added appropriate adjuvant, homogeneous further, it is spray-dried, makes packed nutritive powder, 50g/
Bag, it is 4.08g/ bag that Chinese crude drug content converts into crude drug.
Embodiment 2
Packed nutrition is produced with the optimal processing parameter groped in the optimum ratio of Ricipe for health care food of the present invention and practice process
Powder.
(1)Each taste Chinese crude drug in formula is accurately weighed:Rhizoma Dioscoreae 1900g, Pollen Typhae 1800g, Radix Salviae Miltiorrhizae 1200g, Radix Dipsaci 800g,
Herba Leonuri 1300g, Endoconcha Sepiae 1500g, Radix Angelicae Sinensis 1500g, Radix Rehmanniae Preparata 900g, Rhizoma Cyperi 1100g, Semen Benincasae 1800g, Fructus Lycii 1100g,
Fructus Rubi 700g, Flos Carthami 800g, Radix Astragali 1000g, Colla Corii Asini 1200g, Radix Glycyrrhizae 900g;
(2)By the Colla Corii Asini distilled water molten of 9 times of weight, standby;
(3)By Rhizoma Dioscoreae, Pollen Typhae, Radix Salviae Miltiorrhizae, Radix Dipsaci, Herba Leonuri, Endoconcha Sepiae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Cyperi, Semen Benincasae, Fructus Lycii, cover basin
Son, Flos Carthami, the Radix Astragali, Radix Glycyrrhizae, add the distilled water of initial 12 times of weight of medical material, soak 8 hours, and backflow is decocted 3 hours, filter,
Add the distilled water of 7 times of weight of initial weight, backflow is decocted 2 hours, filter and retain filtering residue, merging filtrate, it is concentrated into 60
DEG C relative density is standby for the concentrated solution of 1.10-1.14;
(4)By step(3)Filtering residue add 7 times of weight concentration 55-85% ethanol, reflux, extract, 2 times, 2 hours every time, filter,
Merging filtrate, vacuum distillation removes ethanol, and it is standby for the concentrated solution of 1.10-1.14 to be concentrated into 60 DEG C of relative densities;
(5)By the Colla Corii Asini of molten and step(3)With(4)The concentrated solution of gained merges, mix homogeneously, continues to be concentrated into 60 DEG C relatively
Density is the concentrated liquid of tradition Chinese medicine of 1.18-1.23, and as Chinese medicine extract, standby;
(6)Semen setariae 4000g, Rhizoma Solani tuber osi 1500g, Radix Ipomoeae 1300g, Amylum Nelumbinis Rhizomatis 700g, Semen Sesami Nigrum 400g, Chinese medicine extract are accurately weighed
800g;
(7)Rhizoma Solani tuber osi, Radix Ipomoeae are cleaned, peeling, stripping and slicing, plus 3 times of decocting in water system 30 minutes, smash to pieces, homogenizing, cross 50 mesh sieves, obtain
Mixed soil, standby;
(8)Semen Sesami Nigrum is crushed and is mixed homogeneously with Semen setariae, plus 12 times of water, boil 20 minutes, by step(6)Chinese medicine extract
And step(7)Mixed soil add mix, be subsequently adding Amylum Nelumbinis Rhizomatis, heat while stirring, continue after mixing to boil 5 minutes, cooling
As raw material health product;
(9)Raw material health product are added appropriate adjuvant, homogeneous further, it is spray-dried, makes packed nutritive powder, 50g/
Bag, it is 4.08g/ bag that Chinese crude drug content converts into crude drug.
Embodiment 3
Sample is provided in order to test to follow-up clinical, with the optimum ratio of Ricipe for health care food of the present invention(Remove food materials with pure shallow lake
Powder replaces)Packed nutritive powder is produced with the optimal processing parameter that gropes in practice process, this nutritive powder is containing only the effective of Chinese crude drug
Composition.
(1)Each taste Chinese crude drug in formula is accurately weighed:Rhizoma Dioscoreae 1900g, Pollen Typhae 1800g, Radix Salviae Miltiorrhizae 1200g, Radix Dipsaci 800g,
Herba Leonuri 1300g, Endoconcha Sepiae 1500g, Radix Angelicae Sinensis 1500g, Radix Rehmanniae Preparata 900g, Rhizoma Cyperi 1100g, Semen Benincasae 1800g, Fructus Lycii 1100g,
Fructus Rubi 700g, Flos Carthami 800g, Radix Astragali 1000g, Colla Corii Asini 1200g, Radix Glycyrrhizae 900g;
(2)By the Colla Corii Asini distilled water molten of 9 times of weight, standby;
(3)By Rhizoma Dioscoreae, Pollen Typhae, Radix Salviae Miltiorrhizae, Radix Dipsaci, Herba Leonuri, Endoconcha Sepiae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Cyperi, Semen Benincasae, Fructus Lycii, cover basin
Son, Flos Carthami, the Radix Astragali, Radix Glycyrrhizae, add the distilled water of initial 12 times of weight of medical material, soak 8 hours, and backflow is decocted 3 hours, filter,
Add the distilled water of 7 times of weight of initial weight, backflow is decocted 2 hours, filter and retain filtering residue, merging filtrate, it is concentrated into 60
DEG C relative density is standby for the concentrated solution of 1.10-1.14;
(4)By step(3)Filtering residue add 7 times of weight concentration 55-85% ethanol, reflux, extract, 2 times, 2 hours every time, filter,
Merging filtrate, vacuum distillation removes ethanol, and it is standby for the concentrated solution of 1.10-1.14 to be concentrated into 60 DEG C of relative densities;
(5)By the Colla Corii Asini of molten and step(3)With(4)The concentrated solution of gained merges, mix homogeneously, continues to be concentrated into 60 DEG C relatively
Density is the concentrated liquid of tradition Chinese medicine of 1.18-1.23, and as Chinese medicine extract, standby;
(6)Pure starch is added water magma is brewed into, by step(5)Chinese medicine extract be proportionally added into mix, then proceed to endure
System 5 minutes, cooling is raw material health product;
(7)Raw material health product are added appropriate adjuvant, homogeneous further, it is spray-dried, makes packed nutritive powder, 50g/
Bag, it is 4.08g/ bag that Chinese crude drug content converts into crude drug.
Embodiment 4
Sample is provided in order to test to follow-up clinical, with the optimum ratio of Ricipe for health care food of the present invention(Remove Chinese crude drug with pure
Gelatinized corn starch replaces Chinese medicine extract)Packed nutritive powder is produced with the optimal processing parameter that gropes in practice process, this nutritive powder is only
Active ingredient containing food materials.
(1)Pure starch is added water magma is brewed into, continue concentrated solution of 60 DEG C of relative densities for 1.18-1.23 is concentrated into,
As Chinese medicine extract substitute, standby;
(2)Semen setariae 4000g, Rhizoma Solani tuber osi 1500g, Radix Ipomoeae 1300g, Amylum Nelumbinis Rhizomatis 700g, Semen Sesami Nigrum 400g, Chinese medicine extract are accurately weighed
Substitute 800g;
(3)Rhizoma Solani tuber osi, Radix Ipomoeae are cleaned, peeling, stripping and slicing, plus 3 times of decocting in water system 30 minutes, smash to pieces, homogenizing, cross 50 mesh sieves, obtain
Mixed soil, standby;
(4)Semen Sesami Nigrum is crushed and is mixed homogeneously with Semen setariae, plus 12 times of water, boil 20 minutes, by step(1)Chinese medicine extract
Substitute and step(3)Mixed soil add mix, be subsequently adding Amylum Nelumbinis Rhizomatis, heat while stirring, continue after mixing to boil 5 points
Clock, cooling is raw material health product;
(5)Raw material health product are added appropriate adjuvant, homogeneous further, it is spray-dried, makes packed nutritive powder, 50g/
Bag.
Embodiment 5
In order to verify the safety of health food of the present invention further, the nutritive powder produced with embodiment 1-4 by inventor is carried out
Toxicity test.
(1)Test material
Experimental animal:SPF level KM mice, body weight 21 ± 4g, SD rat, 222 ± 9g of body weight, equal male and female half and half, by University Of Suzhou
Experimental Animal Center is provided.
Test specimen:The nutritive powder produced by embodiment of the present invention 1-4, specification is the equivalent life of 50g/ bag, Chinese crude drug content
Medicine is 4.08g/ bag.
(2)Acute toxicity test
Mice gives nutritive powder 152g/kg of the present invention by gavage maximum, three times a day, is spaced 4h.Continuous Observation 14d after administration,
All test mice skins, hair color are normal, the normal and secretions without exception in nose, eye, oral cavity, no vomit phenomenon, body weight increase, work
Just normally, there is not unfavorable condition and death to dynamic, diet drinking-water and two in animal.Put to death within 15th day and dissect animal, perusal
Main organs are no abnormal.Rat gives nutritive powder of the present invention by maximum gavage value, 136g/kg, three times a day, continuous after medicine
Observation 14d, all tested rat skins, hair color are normal, the normal and secretions without exception in nose, eye, oral cavity, no vomit phenomenon, body
Growth, activity, diet drinking-water and two are just normal again, and unfavorable condition and death does not occur in animal.Put to death within 15th day and animal dissected,
Perusal main organs are no abnormal.This product mice, one day of rat it is adult to food total amount(Daily 6 bags)13.4
Times, point out health food safety of the present invention very high.
(3)Long term toxicity test
From SD rat 100, male and female half and half, 5 groups are randomly divided into:Blank control group and embodiment of the present invention 1-4 group, to this
Bright nutritive powder, using maximum given low, 3 times a day, continuous to food 6 months, with nutritive powder as staple food, and stops to food 1
The moon makees restorative observation.During test, the outward appearance of observation animal, general behavior, body weight, the change of diet amount of drinking water, are carried out to each group
Hemanalysiss, blood biochemical analysis and organ coefficient, blank control group and high dose group carry out histopathology index checking.
Result of the test shows:Blank control group and nutritive powder each group animal general state of the present invention are good, appearance sign, OK
For activity, glandular secretion, breathing, two just, body weight increase, administration reaction and all changes without exception of drinking water diet amount.Divide in blood
In terms of analysis, indivedual indexs are had to compare with matched group variant, blood biochemical analysis indexes no abnormality seen changes.To food 3 months, stop
It is no substantially poor that food was respectively compared with blank control group to food group organ coefficient after 1 month.To food 3 months, give food 6 months, stop eating 1
After month, the color and luster of each group animal main organs, quality are normal, visually have no and change significantly.Pathological examination, blank
Group has no the Pathologic changes related with food to nutritive powder group main organs tissue.As a result show nutritive powder of the present invention continuous 6
Rat oral gavage was had no significant effect to food in individual month, no clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no and prolongs
Property toxic reaction, points out the dose safety of nutritive powder clinical practice of the present invention very high late.
Embodiment 6
The clinical trial of health food of the present invention
The patient of this clinical trial is all from certain maternity & child care center of city, is that the institute was accepted for medical treatment from June, 2014 in May, 2016
Functional uterine bleeding, therefrom collect 344 patients and voluntarily participate in this clinical trial, these subjects ages
22-54 year, 35.4 years old mean age.Age-based for all experimenters, the course of disease, coincident with severity degree of condition etc. are divided into 4 groups, point
Bian Hao not be blank group, 1 group of control, control 2 groups and test group, per organizing 86 people.
1st, test sample
Blank sample:For the special pure starch of clinical trial, outer package is consistent with nutritive powder of the present invention.
Reference substance 1:The nutritive powder that the embodiment of the present invention 3 is produced, containing only Chinese medicinal ingredients, specification is that 50g/ bag, Chinese crude drug contains
It is 4.08g/ bag that amount converts into crude drug.
Reference substance 2:The nutritive powder that the embodiment of the present invention 4 is produced, containing only food materials composition, specification is 50g/ bag.
Test specimen:The nutritive powder that the embodiment of the present invention 2 is produced with optimum ratio, specification is 50g/ bag, Chinese crude drug content
Equivalent crude drug is 4.08g/ bag.
2nd, test method
All patients all on the basis of the treatment meanss for actively coordinating hospital, edible nutritive powder of the present invention.The edible sky of blank group
White sample, compares 1 group and eats reference substance 1, compares 2 groups and eats reference substance 2, and test group eats test specimen, each group all daily 3
Secondary, use with canteen, continuous using two months, in process of the test, carefully record compares the sign change of each group patient, final statistics
Therapeutic outcome.Carry out paying a return visit record recurrent cases to curing patient after six months.
3rd, result of the test judgment criteria
Because the present invention is health food, which is have functions that health care and auxiliary treatment, and therefore, evaluation effect is simply in statistics
On the basis of hospital is to the normal therapeutic result statistics of dysfunctional uterine hemorrhage, see whether help is had or not to normal therapeutic.Mainly
Passed judgment on from the two angles of statistical analysiss of the change of patient sign body-sensing and cure rate.
4th, result of the test
(1)Sign body-sensing changes:Test group patient complexion be significantly better than remaining each group, test group patient have rosy cheeks glossy,
No sweating due to debility, take off the body void phenomenons such as power, lumbago, knee joint be soft, whether no matter cure blank group patient all have different degrees of body void by disease
Phenomenon, remaining two groups are slightly more excellent than blank group, but not as good as test group.
(2)Result of the test statistical analysiss
After test all terminates, result of the test is carried out statistical analysiss as shown in table 1.
1 result of the test statistical analysis table of table
5th, conclusion (of pressure testing)
As can be seen from the test results, health product of the present invention intuitively can show from surface characteristics, with significantly conditioning
And health-care effect.Can be seen that compared with blank group from result of the test statistical analysis table, the cure rate of test group improves 19.7
Percentage point, total effective rate improves 15.1 percentage points, and relapse rate reduces 21.6 percentage points.And this health care and
Adjuvant treatment effect is illustrated health food of the present invention, is not several food materials significantly better than the superposition of two matched group test effects
Simply it is superimposed with several medical materials, but gropes repeatedly research and development, meticulous compatibility through scientific research and form, makes the effect of Chinese crude drug and food materials
Fruit there occurs cooperative effect, thus generate unexpected health-care effect, and therefore, the creativeness of the present invention is should be not ignored
's.
Claims (4)
1. the edible health food of a kind of confession functional uterine bleeding, it is characterised in that the formula of the health food with
Weight portion is calculated as:Semen setariae 20-80 part, Rhizoma Solani tuber osi 7-30 part, Radix Ipomoeae 7-30 part, Amylum Nelumbinis Rhizomatis 1-15 part, Semen Sesami Nigrum 1-9 part, Chinese medicine are carried
Take thing 2-15 part;
Chinese medicine extract:Rhizoma Dioscoreae 9-30 part, Pollen Typhae 8-28 part, Radix Salviae Miltiorrhizae 6-19 part, Radix Dipsaci 4-13 part, Herba Leonuri 6-19 part, sea Piao
Octopus ocellatus Gray 7-25 part, Radix Angelicae Sinensis 8-28 part, Radix Rehmanniae Preparata 4-16 part, Rhizoma Cyperi 5-17 part, Semen Benincasae 8-27 part, Fructus Lycii 6-18 part, Fructus Rubi 4-
12 parts, Flos Carthami 4-13 part, Radix Astragali 5-16 part, Colla Corii Asini 6-20 part, Radix Glycyrrhizae 5-13 part.
2. the health food that confession functional uterine bleeding as claimed in claim 1 eats, it is characterised in that the health care
The formula of food is in parts by weight:40 parts of Semen setariae, 15 parts of Rhizoma Solani tuber osi, 13 parts of Radix Ipomoeae, 7 parts of Amylum Nelumbinis Rhizomatis, 4 parts of Semen Sesami Nigrum, Chinese medicine are carried
Take 8 parts of thing;
Chinese medicine extract:19 parts of Rhizoma Dioscoreae, 18 parts of Pollen Typhae, 12 parts of Radix Salviae Miltiorrhizae, 8 parts of Radix Dipsaci, 13 parts of Herba Leonuri, 15 parts of Endoconcha Sepiae, Radix Angelicae Sinensis
15 parts, 9 parts of Radix Rehmanniae Preparata, 11 parts of Rhizoma Cyperi, 18 parts of Semen Benincasae, 11 parts of Fructus Lycii, 7 parts of Fructus Rubi, 8 parts of Flos Carthami, 10 parts of the Radix Astragali, Colla Corii Asini 12
Part, 9 parts of Radix Glycyrrhizae.
3. the health food that confession functional uterine bleeding as claimed in claim 1 or 2 eats, it is characterised in that described
The preparation method of health food is following steps:
(1)Chinese medicine extract in formula used by Chinese crude drug is accurately weighed;
(2)By the Colla Corii Asini distilled water molten of 5-12 times of weight, standby;
(3)By Rhizoma Dioscoreae, Pollen Typhae, Radix Salviae Miltiorrhizae, Radix Dipsaci, Herba Leonuri, Endoconcha Sepiae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Rhizoma Cyperi, Semen Benincasae, Fructus Lycii, cover basin
Son, Flos Carthami, the Radix Astragali, Radix Glycyrrhizae, add the distilled water of initial 7-17 times of weight of medical material, soak 4-24 hour, and it is little that backflow decocts 1-6
When, to filter, the distilled water of 4-11 times of weight of initial weight is added, backflow decocts 1-5 hour, filters and retain filtering residue, merges
Filtrate, the concentrated solution for being concentrated into 60 DEG C of relative densities for 1.10-1.14 is standby;
(4)By step(3)Filtering residue add 5-12 times of weight concentration 55-85% ethanol, reflux, extract, 2 times, each 1-6 hour,
Filter, merging filtrate, vacuum distillation removes ethanol, and it is standby for the concentrated solution of 1.10-1.14 to be concentrated into 60 DEG C of relative densities;
(5)By the Colla Corii Asini of molten and step(3)With(4)The concentrated solution of gained merges, mix homogeneously, continues to be concentrated into 60 DEG C relatively
Density is the concentrated liquid of tradition Chinese medicine of 1.18-1.23, and as Chinese medicine extract, standby;
(6)Semen setariae, Rhizoma Solani tuber osi, Radix Ipomoeae, Amylum Nelumbinis Rhizomatis, Semen Sesami Nigrum, Chinese medicine extract are accurately weighed;
(7)Rhizoma Solani tuber osi, Radix Ipomoeae are cleaned, peeling, stripping and slicing, plus 1-5 times of decocting in water 10-60 minute, smash to pieces, homogenizing, mistake 40-80
Mesh sieve, obtains mixed soil, standby;
(8)Semen Sesami Nigrum is crushed and is mixed homogeneously with Semen setariae, plus 5-18 times of water, 15-60 minute is boiled, by step(6)Chinese medicine
Extract and step(7)Mixed soil add mix, be subsequently adding Amylum Nelumbinis Rhizomatis, heat while stirring, continue after mixing to boil 2-20
Minute, cooling is raw material health product;
(9)Raw material health product can be added appropriate adjuvant, such as sucrose, Mel, sweetener, Sal, essence, vegetable, pigment
Deng adjuvant, using modern general processing and packing technique, health food is made.
4. the health food that confession functional uterine bleeding as claimed in claim 1 or 2 eats, it is characterised in that:Described
Health food can make liquid medicated porridge or nutritive powder.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201611226221.6A CN106418528A (en) | 2016-12-27 | 2016-12-27 | Health food for functional uterine bleeding patients and preparation method of health food |
Applications Claiming Priority (1)
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CN101116490A (en) * | 2007-08-30 | 2008-02-06 | 付东升 | Lotus root full-powder and method for preparing the same |
CN101757248A (en) * | 2009-11-27 | 2010-06-30 | 赵德润 | Compound donkey-hide gelatin cake for woman |
CN103330809A (en) * | 2013-07-23 | 2013-10-02 | 黄淑娟 | Traditional Chinese medicine composition for curing functional uterine bleeding |
CN103734710A (en) * | 2013-11-26 | 2014-04-23 | 威海纽麦斯保健品有限责任公司 | Functional food able to supplement qi and blood and preparation method thereof |
CN104740467A (en) * | 2015-04-20 | 2015-07-01 | 王雪雁 | Traditional Chinese medicine preparation for treating functional uterine bleeding and production process of traditional Chinese medicine preparation |
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CN1241423A (en) * | 1998-06-26 | 2000-01-19 | 樊祖仁 | Preparation of medicine for functional metrorrhagia |
CN1480173A (en) * | 2002-12-06 | 2004-03-10 | 长沙市泰宝制药有限公司 | Chinese herbal medicine for treating gynecology disease and its preparing method |
CN101116490A (en) * | 2007-08-30 | 2008-02-06 | 付东升 | Lotus root full-powder and method for preparing the same |
CN101757248A (en) * | 2009-11-27 | 2010-06-30 | 赵德润 | Compound donkey-hide gelatin cake for woman |
CN103330809A (en) * | 2013-07-23 | 2013-10-02 | 黄淑娟 | Traditional Chinese medicine composition for curing functional uterine bleeding |
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