CN106413689A - 制备药物组合物的方法和装置 - Google Patents

制备药物组合物的方法和装置 Download PDF

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Publication number
CN106413689A
CN106413689A CN201580030280.3A CN201580030280A CN106413689A CN 106413689 A CN106413689 A CN 106413689A CN 201580030280 A CN201580030280 A CN 201580030280A CN 106413689 A CN106413689 A CN 106413689A
Authority
CN
China
Prior art keywords
weight
extrusion
pharmaceutical composition
implant
extruder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580030280.3A
Other languages
English (en)
Chinese (zh)
Inventor
穆拉德·鲁曼
马尔科·斯皮茨
土肥元
土肥元一
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asino Supply Co
Original Assignee
Asino Supply Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asino Supply Co filed Critical Asino Supply Co
Publication of CN106413689A publication Critical patent/CN106413689A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
CN201580030280.3A 2014-04-30 2015-04-24 制备药物组合物的方法和装置 Pending CN106413689A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE102014006325.9 2014-04-30
DE102014006325 2014-04-30
EP14001993 2014-06-10
EP14001993.6 2014-06-10
PCT/EP2015/058947 WO2015165821A1 (fr) 2014-04-30 2015-04-24 Procédé et dispositif pour la fabrication d'une composition pharmaceutique

Publications (1)

Publication Number Publication Date
CN106413689A true CN106413689A (zh) 2017-02-15

Family

ID=53005570

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580030280.3A Pending CN106413689A (zh) 2014-04-30 2015-04-24 制备药物组合物的方法和装置

Country Status (3)

Country Link
EP (1) EP3137061A1 (fr)
CN (1) CN106413689A (fr)
WO (1) WO2015165821A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4156913A (en) * 1976-09-24 1979-05-29 The Goodyear Tire & Rubber Company Method and apparatus for controlling the thickness of extruded stock
CN1200032A (zh) * 1996-09-04 1998-11-25 R·德根格希 制备含有生物活性肽的植入物的方法
WO2002013793A2 (fr) * 2000-08-16 2002-02-21 Rexall Sundown, Inc. Procede de fabrication de comprimes et compositions de comprimes produites conformement audit procede
CN1938040A (zh) * 2003-03-05 2007-03-28 Pr药品有限公司 缩宫素控释制剂及其应用方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4156913A (en) * 1976-09-24 1979-05-29 The Goodyear Tire & Rubber Company Method and apparatus for controlling the thickness of extruded stock
CN1200032A (zh) * 1996-09-04 1998-11-25 R·德根格希 制备含有生物活性肽的植入物的方法
WO2002013793A2 (fr) * 2000-08-16 2002-02-21 Rexall Sundown, Inc. Procede de fabrication de comprimes et compositions de comprimes produites conformement audit procede
CN1938040A (zh) * 2003-03-05 2007-03-28 Pr药品有限公司 缩宫素控释制剂及其应用方法

Also Published As

Publication number Publication date
WO2015165821A1 (fr) 2015-11-05
EP3137061A1 (fr) 2017-03-08

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Legal Events

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C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information
CB02 Change of applicant information

Address after: Basel

Applicant after: Green leaf supply company

Address before: Swiss aesch

Applicant before: Asino supply company

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20170215