CN106390278A - Ultrasonic therapeutic apparatus - Google Patents
Ultrasonic therapeutic apparatus Download PDFInfo
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- CN106390278A CN106390278A CN201610905289.0A CN201610905289A CN106390278A CN 106390278 A CN106390278 A CN 106390278A CN 201610905289 A CN201610905289 A CN 201610905289A CN 106390278 A CN106390278 A CN 106390278A
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- 230000001225 therapeutic effect Effects 0.000 title abstract description 13
- 239000003814 drug Substances 0.000 claims abstract description 85
- 238000002560 therapeutic procedure Methods 0.000 claims abstract description 44
- 239000000758 substrate Substances 0.000 claims abstract description 27
- 238000002347 injection Methods 0.000 claims description 26
- 239000007924 injection Substances 0.000 claims description 26
- 238000005086 pumping Methods 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 16
- 230000007246 mechanism Effects 0.000 claims description 16
- 230000008595 infiltration Effects 0.000 claims description 14
- 238000001764 infiltration Methods 0.000 claims description 14
- 239000008280 blood Substances 0.000 claims description 10
- 210000004369 blood Anatomy 0.000 claims description 10
- 238000013268 sustained release Methods 0.000 claims description 10
- 239000012730 sustained-release form Substances 0.000 claims description 10
- 238000002604 ultrasonography Methods 0.000 claims description 9
- 238000009434 installation Methods 0.000 claims description 8
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 5
- 230000005484 gravity Effects 0.000 claims description 5
- 229910052760 oxygen Inorganic materials 0.000 claims description 5
- 239000001301 oxygen Substances 0.000 claims description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 4
- 239000008103 glucose Substances 0.000 claims description 4
- 239000007779 soft material Substances 0.000 claims description 4
- 238000000151 deposition Methods 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 18
- 230000005284 excitation Effects 0.000 abstract description 7
- 238000010521 absorption reaction Methods 0.000 abstract description 3
- 238000010438 heat treatment Methods 0.000 abstract description 2
- 230000026683 transduction Effects 0.000 abstract 2
- 238000010361 transduction Methods 0.000 abstract 2
- 230000003833 cell viability Effects 0.000 abstract 1
- 230000008859 change Effects 0.000 description 14
- 229940079593 drug Drugs 0.000 description 9
- 230000002463 transducing effect Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 238000012377 drug delivery Methods 0.000 description 4
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- 238000001514 detection method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
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- 230000002459 sustained effect Effects 0.000 description 3
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- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3368—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0034—Skin treatment
Abstract
The invention relates to the field of medical apparatus and instruments, in particular to an ultrasonic therapeutic apparatus. The ultrasonic therapeutic apparatus comprises an ultrasonic therapeutic patch, a therapy host computer, an attaching unit and at least one ultrasonic transduction unit, wherein the ultrasonic therapeutic patch is attached on skin surface and used for permeating medicine into the skin surface by utilizing ultrasonic wave; the therapy host computer is connected with the therapy patch and used for outputting an excitation signal to control the ultrasonic therapeutic patch, the ultrasonic therapeutic patch comprises a patch substrate, at least one medicine lumen is arranged on the patch substrate; the attaching unit is distributed at the periphery of the bottom of the patch substrate and used for being attached on the skin surface; and at least one ultrasonic transduction unit is arranged on the patch substrate and is used for transmitting ultrasonic wave to the skin surface under the condition that a first excitation signal is received and producing heat to increase temperature by heating under the condition that a second excitation signal is received. The ultrasonic therapeutic apparatus provided by the invention has the advantages that pharmaceutical molecule activity and cell viability are improved, then medicine permeation absorption efficiency is improved, and therapy and restoration are sped up.
Description
Technical field
The present invention relates to medical instruments field is and in particular to a kind of sonicator.
Background technology
Ultrasonic technology has obtained the generally accreditation of medical circle in unique curative effect of medical aspect, and increasingly by clinical weight
Depending on and adopt.Through research, ultrasonic activation can cause the motion of matter in histocyte, so that cell liquid is flowed, change cell membrane
Permeability, stimulate cell pellicle disperse process, promote cell metabolism, promote area for treatment microcirculation, improve
Histotrophic nutrition, change protein synthesis, raising regenerative function etc..When in ultrasonic wave communication process in tissue, its energy
Constantly it is absorbed by tissue and becomes heat, improve enzyme and cytoactive in appropriate scope, this thermogenetic effect can increase blood
Circulation, accelerates metabolism, improves local organization nutrition, strengthens enzyme activity, improves treatment and the effect recovered.The penetration power of ultrasonic wave
By force, internal 10 15cm can be deep into easily, also have certain therapeutic action to internal tissue.Medical expert utilizes both at home and abroad
Ultrasonic technology is long-pending in terms for the treatment of limbs soft tissue injury, limbs chronic ache rehabilitation, limb motion rehabilitation to be achieved very
Good curative effect, and ultrasonic therapy is extended to department of traditional Chinese medicine, orthopaedics, surgery, internal medicine, paediatrics, oncology, andrology, gynemetrics etc.,
Clinic is extensively applied, and achieves satisfied therapeutic effect.
At present, existing sonicator mainly carries out short term contact formula treatment by ultrasonic therapeutic probe, or passes through glue
Similar device of popping one's head in is affixed on the treatment that affected part carries out short-term by patch, bandage etc..Existing sonicator is more concerned with how drawing
Play histiocytic change to promote drug absorption, and the low effect that also can affect Medicated Permeation absorption of the active degree of drug molecule
Rate is so that treatment speed is slow, recovery effects are inconspicuous.
Content of the invention
The technical problem to be solved in the present invention is that sonicator of the prior art divides due to not accounting for medicine
The active degree of son makes that the efficiency that Medicated Permeation absorbs is low, treatment speed is slow, recovery effects are inconspicuous, thus providing a kind of super
Sound therapeutic equipment.
A kind of one side of the embodiment of the present invention, there is provided sonicator, including:Ultrasonic therapy paster, is attached to skin
Skin surface, for entering described skin surface using ultrasonic wave by Medicated Permeation;Treatment main frame, with described ultrasonic therapy paster even
Connect, for output drive signal to control described ultrasonic therapy paster, wherein, described ultrasonic therapy paster includes:Paster substrate,
At least one medicine tube chamber is set thereon;Attach unit, be distributed in the bottom surrounding of described paster substrate, be used for being attached to skin
Surface;At least one ultrasonic wave transducer unit, is arranged in described paster substrate, in the situation receiving the first pumping signal
Lower to described skin surface launch ultrasonic wave;Produce heat energy to carry out at heat temperature raising in the case of receiving the second pumping signal
Reason.
Alternatively, described treatment main frame includes:Ultrasound-driven device, is connected with described ultrasonic wave transducer unit, for producing
Raw described pumping signal.
Alternatively, described treatment main frame includes:Sustained release chemicals-injection mechanism, is connected with described ultrasonic therapy paster by conduit,
For to injection of medicine in described medicine tube chamber.
Alternatively, described sustained release chemicals-injection mechanism includes:Medicament reservoir, is used for depositing medicine;Injection actuating unit, for
Described medicament reservoir applies pressure and will wherein extrude medicine.
Alternatively, described sustained release chemicals-injection mechanism also includes:Clamping device, for clamping described medicament reservoir.
Alternatively, described treatment main frame includes:Electric supply installation, wherein, described electric supply installation includes:Battery and discharge and recharge electricity
Road.
Alternatively, described ultrasonic therapy paster also includes at least one of:Temperature sensor, blood oxygen transducer, blood sugar
Sensor, acidity-basicity sensor, gravity sensor, EGC sensor, humidity sensor.
Alternatively, described attaching unit is removably disposed in the bottom surrounding of described paster substrate.
Alternatively, it is provided with liquid infiltration unit in described medicine tube chamber, for infiltrating the liquid medicine of injection, wherein,
Described liquid infiltration unit is removably disposed in described medicine tube chamber.
Alternatively, described paster substrate is the substrate made using soft material.
In the present embodiment, by treatment host computer control ultrasonic wave transducer unit, both be can be used for using ultrasonic wave transducer unit
Transmitting ultrasonic wave is to change histiocytic activity it is also possible to produce heat energy with affected part to be treated to skin, paster and medicine etc.
Heated, improve activity and the cytoactive of drug molecule, and then lift the efficiency that Medicated Permeation absorbs, accelerate treatment speed
And recovery effects.
In order to ensure that being sustained chemicals-injection mechanism repeats utilization, save resources, medicament reservoir may be selected disposable syringe,
And removably configuration is installed, thus being convenient for changing.Fix medicament reservoir by gripping apparatus grips, when need change medicine
During container, unclamp clamping device, take out medicament reservoir and carry out changing.
The ultrasonic therapy paster of the present embodiment can be pasted and fixed on patient region to be treated for a long time, is not just affecting patient
Under the purpose of often action life, reach the long-time effect treated and recover.And this paster can be by changing sticking area
Viscose glue is repeatedly used, and reduces and changes the treatment cost using.
Brief description
In order to be illustrated more clearly that the specific embodiment of the invention or technical scheme of the prior art, below will be to concrete
In embodiment or description of the prior art the accompanying drawing of required use be briefly described it should be apparent that, below describe in
Accompanying drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not paying creative work
Put, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the schematic diagram of a specific example of sonicator in the embodiment of the present invention;
Fig. 2 is the schematic diagram of the specific example of ultrasonic therapy paster shown in Fig. 1;
Fig. 3 is the schematic diagram of another specific example of sonicator of the embodiment of the present invention.
Specific embodiment
Below in conjunction with accompanying drawing, technical scheme is clearly and completely described with the enforcement it is clear that described
Example is a part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill
The every other embodiment that personnel are obtained under the premise of not making creative work, broadly falls into the scope of protection of the invention.
In describing the invention, it should be noted that term " " center ", " on ", D score, "left", "right", " vertical ",
The orientation of instruction such as " level ", " interior ", " outward " or position relationship are based on orientation shown in the drawings or position relationship, merely to
Be easy to describe the present invention and simplify description, rather than instruction or the hint device of indication or element must have specific orientation,
With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.Additionally, term " first ", " second ",
" the 3rd " is only used for describing purpose, and it is not intended that indicating or hint relative importance.
In describing the invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or is integrally connected;Can
To be to be mechanically connected or electrical connection;Can be to be joined directly together it is also possible to be indirectly connected to by intermediary, acceptable
It is the connection of two element internals, can be wireless connection or wired connection.For those of ordinary skill in the art
For, above-mentioned term concrete meaning in the present invention can be understood with concrete condition.
As long as additionally, the non-structure each other of involved technical characteristic in invention described below different embodiments
Become conflict just can be combined with each other.
The present embodiment provides a kind of sonicator, as shown in figure 1, this sonicator includes:Ultrasonic therapy paster 10
With treatment main frame 20.
Ultrasonic therapy paster 10 is attached to skin surface, for Medicated Permeation being entered skin surface using ultrasonic wave;Treatment
Main frame 20 is connected with ultrasonic therapy paster 10, for output drive signal to control ultrasonic therapy paster 10, this pumping signal bag
Include the first pumping signal and the second pumping signal, as shown in Fig. 2 ultrasonic therapy paster 10 includes:Paster substrate 101, sets thereon
Put at least one medicine tube chamber 1011, can be with injection of medicine in this medicine tube chamber 101, different pharmaceutical tube chamber 101 can inject not
Same medicine;Attach unit 102, be distributed in the bottom surrounding of paster substrate 101, be used for being attached to skin surface;At least one
Ultrasonic wave transducer unit 103, is arranged in paster substrate 101, for receive the first pumping signal in the case of to skin table
Surface launching ultrasonic wave;Produce heat energy to carry out heat temperature raising process in the case of receiving the second pumping signal.Wherein, heating rises
The region of temperature includes skin affected part to be treated, paster and medicine etc..
In the present embodiment, by treatment host computer control ultrasonic wave transducer unit, both be can be used for using ultrasonic wave transducer unit
Transmitting ultrasonic wave is to change histiocytic activity it is also possible to produce heat energy with affected part to be treated to skin, paster and medicine etc.
Heated, improve activity and the cytoactive of drug molecule, and then lift the efficiency that Medicated Permeation absorbs, accelerate treatment speed
And recovery effects.
It should be noted that the ultrasonic therapy paster 10 shown in Fig. 1 and Fig. 2 is only a kind of example of the embodiment of the present invention,
Ultrasonic therapy paster described in the embodiment of the present invention be not limited to square or circular, oval etc. shown in figure, ultrasonic
Ripple transducing unit is also not necessarily limited to spacing side by side set-up mode shown in figure with the position relationship of medicine tube chamber, can also be such as ring
Shape interval setting.
Alternatively, above-mentioned pumping signal can be continuous wave, short pulse or continuously involve applied in short pulse intervals excitation signal, its
In, the frequency of the first pumping signal is located near resonance point, launches ultrasonic wave with excitation ultrasound ripple transducing unit;Second excitation letter
Number frequency domain off-resonance point, with excitation ultrasound ripple transducing unit heat production, medicine is heated.
Specifically, the ultrasonic therapy paster of the embodiment of the present invention can adjust the mode of operation of ultrasonic wave transducer unit, tool
Body shows as ultrasonic wave transducer cell operation and is divided into resonant operational state and disresonance working condition, under resonant operational state,
This ultrasonic wave transducer unit launches ultrasonic wave;Under disresonance working condition, this ultrasonic wave transducer cell mesh energy directly turns
Be changed to heat energy dissipation, realize the warming function of this paster, in the scope of safety improve temperature can accelerate area for treatment treatment and
The effect recovered.
As a kind of optional embodiment of above-described embodiment, the ultrasonic therapy paster described in the present embodiment also includes following
At least one:Temperature sensor, blood oxygen transducer, blood glucose sensor, acidity-basicity sensor, gravity sensor, EGC sensor,
Humidity sensor, these sensors all can be arranged in paster substrate, and wherein, temperature sensor is used for detecting that ultrasonic therapy is pasted
The temperature of piece.Specifically, temperature sensor is arranged on the inside of paster substrate, and the temperature of detection ultrasonic therapy paster can be used for
Carry out temperature controlled feedback regulation, thus realizing the precise control of temperature.On the other hand, this temperature sensor can be also used for
The temperature change of detection tissue, in order to make corresponding adjustment according to human body temperature;Blood oxygen transducer is used for detecting human body
Blood oxygen concentration;Blood glucose sensor is used for detecting human blood glucose concentration;Acidity-basicity sensor is used for detecting medicine or skin surface
Acid-base value;Gravity sensor is used for detecting Gravity changer;EGC sensor is used for detecting electrocardiosignal;Humidity sensor is used for
Detection medicine or the humidity of skin surface.
As shown in Fig. 2 when ultrasonic wave transducer unit 103 be multiple when, multiple ultrasonic wave transducer units 103 be divided into one group or
Multigroup, wherein, the ultrasonic wave transducer unit 103 of different groups excites simultaneously or timesharing excites.Multiple ultrasonic waves shown in Fig. 2
Can unit 103 composition row, constitute one group of ultrasonic wave transducer unit 103, ultrasonic wave transducer unit 103 is with net distribution in patch
The bottom of piece substrate, is connected with treatment main frame each via cable conductor.
As shown in figure 1, the ultrasonic therapy paster 10 of the present embodiment also includes:Connecting interface 104, by connecting line 30 with control
Treat main frame 20 to connect.Wherein, this connecting interface 104 includes:Electric signal interface, is connected with ultrasonic wave transducer unit;Drug catheter
Interface, is connected (in figure is all not shown) with medicine tube chamber.Wherein, electric signal interface is also connected with above-mentioned middle sensor, and connection connects
Mouth 104 be will be implanted in medicine tube chamber 1011 by medicine-pouring pipe 1012, infiltrates unit infiltration by liquid.Treatment main frame can lead to
Cross connecting line to be connected with connecting interface, realize infusion of medicine and control signal and the transmission of temperature information, wherein, connecting line bag
Containing signal-transmitting cable and drug delivery catheter.In order to prevent connecting interface 104 from coming off, this interface can be passed through buckle solid
It is scheduled in paster substrate.
The ultrasonic therapy paster of the embodiment of the present invention is affixed on affected part for a long time and is treated, difficult in order to reduce dressing administration,
Drug delivery structure is devised on this paster, that is, passes through connecting interface to injection of medicine in ultrasonic therapy paster, do not needing to carry out
In the case of taking off, re-pasting, realize being directly administered by being administered result, this medicine is with present using external application or embrocate fluid-like state
Based on medicine, or even realize needleless administered intramuscular mode.
It should be noted that the connecting interface position of the embodiment of the present invention is not limited to the back side centre bit of ultrasonic therapy paster
Put, can be in side or off-center position;Wherein connecting interface quantity is not limited to 1, can be according to ultrasonic wave transducer unit
The quantity of array group or medicine tube chamber quantity are adjusted, and Fig. 1 is only a kind of example of the present invention, does not make improper limit
Fixed.
As a kind of optional embodiment, as shown in figure 3, treatment main frame 20 includes:Ultrasound-driven device 201, and ultrasonic
Ripple transducing unit 103 connects (not shown), for producing pumping signal.This pumping signal includes above-mentioned first pumping signal
With the second pumping signal.Ultrasound-driven device 201 is by the electric signal connecting line and the electric signal that are arranged in above-mentioned connecting line 30
Interface connects, to realize the connection with ultrasonic wave transducer unit 103.
Ultrasound-driven device 201 produces pumping signal (that is to say drive signal) and is used for driving surpassing on ultrasonic therapy paster
Sound wave transducing unit 103, this pumping signal can be short pulse or continuous impulse.Alternatively, the treatment main frame 20 of the present embodiment
Also include:Control indication mechanism 202, above-mentioned pulse frequency, repetition rate, amplitude can be carried out by controlling indication mechanism 202
Adjust.Ultrasound-driven device 201 can produce at least 1 road signal simultaneously, drives at least 1 road ultrasonic wave transducer unit or ultrasonic waves
Can unit group (for example, string or referred to as one group of ultrasound emission unit being connected in parallel being connected to by wire).Above-mentioned control shows
Show that mechanism 202 can be used for controlling and show the functional and working condition of this sonicator, this control mode comprise but not
It is limited to the mode of button, knob, touch-screen, indicator lamp.Further, indication mechanism 202 is controlled can to include wireless telecommunications mould
Block, in order to carry out transmission of wireless signals, specifically, can realize signal transmission and job control by bluetooth, WIFI pattern
Function.
As a kind of optional embodiment, the treatment main frame 20 of the present embodiment can also include:Sustained release chemicals-injection mechanism 203,
It is connected with ultrasonic therapy paster 10 by conduit, for injection of medicine in medicine tube chamber 1011.Sustained release chemicals-injection mechanism 203 medicine
Output interface is connected with the drug delivery conduit in connecting line 30, and this conduit is by drug delivery to ultrasonic therapy paster 10.Medicine
Transmitting catheter is not limited to 1 tube chamber, can have multiple tube chambers, for connecting multiple medicament reservoirs, is sustained different types of medicine
Thing.
As further preferred embodiment, above-mentioned sustained release chemicals-injection mechanism 203 includes:Medicament reservoir, is used for depositing medicine
Thing;Injection actuating unit, will wherein extrude medicine for applying pressure to medicament reservoir.Said medicine container can be injection
Device, but it is not limited to syringe.
In order to ensure that being sustained chemicals-injection mechanism repeats utilization, save resources, medicament reservoir may be selected disposable syringe,
And removably configuration is installed, thus being convenient for changing.Specifically, sustained release chemicals-injection mechanism also includes:Clamping device, for clamping medicine
Thing container.Fix medicament reservoir by gripping apparatus grips, when needing to change medicament reservoir, unclamp clamping device, take out
Medicament reservoir carries out changing.
Further, injection dynamic structure can at least include a motor and mechanical transmission structure, mechanical transmission structure
For the power of motor is applied to medicament reservoir.
As a kind of optional embodiment, in order to ensure the portability of sonicator, the treatment main frame 20 of the present embodiment
Including:Electric supply installation 204, wherein, electric supply installation 204 includes:Battery and charge-discharge circuit.Battery can be lithium battery.This confession
Electric installation is used for powering to whole sonicator, and this makes sonicator not limited by power supply, and portability is preferable.
As a kind of preferred embodiment, the paster substrate of the present embodiment is the substrate made using soft material.Soft
Material can be rubber or the material with same performance so that ultrasonic therapy paster can occur with the fold of skin surface
Corresponding deformation and be unlikely to come off, thus ensureing that ultrasonic therapy paster can be attached to human skin for a long time, realize
Long-time treatment, and then lift therapeutic effect.
Alternatively, the thickness of the ultrasonic therapy paster of the embodiment of the present invention is 1~5mm, with respect to existing ultrasonic therapy
Probe, its thickness substantially reduces, thus guaranteeing to be unlikely to come off with the bending change of skin.
As a kind of optional embodiment, paster substrate is provided with region of leaving a blank, this region can carry out other operations,
Such as needle-free drug injection etc..
As one kind preferred embodiment, attach the bottom surrounding that unit is removably disposed in paster substrate.Make patch
Coupon unit has dismountable feature so that this attaching unit can be changed, so that the ultrasonic therapy of the application
Paster is reused, and increases operation rate.Further, in order to ensure that attaching unit is preferably attached to skin surface, can adopt
The sticking tablet made with the material with preferable biocompatibility is as attaching unit.
The ultrasonic therapy paster of the present embodiment can be pasted and fixed on patient region to be treated for a long time, is not just affecting patient
Under the purpose of often action life, reach the long-time effect treated and recover.And this paster can be by changing sticking area
Viscose glue is repeatedly used, and reduces and changes the treatment cost using.
As a kind of preferred embodiment, it is provided with liquid infiltration unit in medicine tube chamber, for the liquid of infiltration injection
Medicine.It is injected into the infiltration of medicine intraluminal liquid medicine on liquid infiltration unit, change liquid infiltration unit and skin surface
Contact, so that the medicine on liquid infiltration unit is to Cutaneous permeation.
It is further preferred that liquid infiltration unit is removably disposed in medicine tube chamber, thus ensure that ultrasonic therapy
The reuse of paster, when changing medicine or reusing, changes liquid infiltration unit in medicine tube chamber.
As a kind of preferred embodiment, medicine tube chamber is multiple, and multiple medicine tube chambers can be used for injecting identical medicine
Thing is it is also possible to inject different medicines.
Obviously, above-described embodiment is only intended to clearly illustrate example, and the not restriction to embodiment.Right
For those of ordinary skill in the art, can also make on the basis of the above description other multi-forms change or
Change.There is no need to be exhaustive to all of embodiment.And the obvious change thus extended out or
Change among still in the protection domain of the application.
Claims (10)
1. a kind of sonicator is it is characterised in that include:
Ultrasonic therapy paster, is attached to skin surface, for Medicated Permeation being entered described skin surface using ultrasonic wave;
Treatment main frame, is connected with described ultrasonic therapy paster, for output drive signal to control described ultrasonic therapy paster,
Wherein, described ultrasonic therapy paster includes:
Paster substrate, arranges at least one medicine tube chamber thereon;
Attach unit, be distributed in the bottom surrounding of described paster substrate, be used for being attached to skin surface;
At least one ultrasonic wave transducer unit, is arranged in described paster substrate, in the situation receiving the first pumping signal
Lower to described skin surface launch ultrasonic wave;Produce heat energy to carry out at heat temperature raising in the case of receiving the second pumping signal
Reason.
2. sonicator according to claim 1 is it is characterised in that described treatment main frame includes:
Ultrasound-driven device, is connected with described ultrasonic wave transducer unit, for producing described pumping signal.
3. sonicator according to claim 1 and 2 is it is characterised in that described treatment main frame includes:
Sustained release chemicals-injection mechanism, is connected with described ultrasonic therapy paster by conduit, for injection of medicine in described medicine tube chamber.
4. sonicator according to claim 3 is it is characterised in that described sustained release chemicals-injection mechanism includes:
Medicament reservoir, is used for depositing medicine;
Injection actuating unit, will wherein extrude medicine for applying pressure to described medicament reservoir.
5. sonicator according to claim 4 is it is characterised in that described sustained release chemicals-injection mechanism also includes:
Clamping device, for clamping described medicament reservoir.
6. sonicator according to claim 1 and 2 is it is characterised in that described treatment main frame includes:Electric supply installation,
Wherein, described electric supply installation includes:Battery and charge-discharge circuit.
7. sonicator according to claim 1 it is characterised in that described ultrasonic therapy paster also include following at least
One of:
Temperature sensor, blood oxygen transducer, blood glucose sensor, acidity-basicity sensor, gravity sensor, EGC sensor, humidity
Sensor.
8. sonicator according to claim 1 it is characterised in that described attaching unit be removably disposed in described
The bottom surrounding of paster substrate.
9. sonicator according to claim 1 is it is characterised in that be provided with liquid infiltration list in described medicine tube chamber
Unit, for the liquid medicine of infiltration injection, wherein, described liquid infiltration unit is removably disposed in described medicine tube chamber.
10. sonicator according to claim 1 is it is characterised in that described paster substrate is using soft material system
The substrate becoming.
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CN112057415A (en) * | 2019-06-10 | 2020-12-11 | 海得摩尔医药科技有限公司 | Gel preparation for transdermal administration and use thereof |
WO2020249013A1 (en) * | 2019-06-10 | 2020-12-17 | 海得摩尔医药科技有限公司 | Transdermal administration method, preparation, and device |
CN115999037A (en) * | 2023-02-17 | 2023-04-25 | 西安交通大学医学院第一附属医院 | Ultrasonic drug delivery system |
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