CN106389815A

CN106389815A - Traditional Chinese medicine composition for treating child bronchitis and preparation method thereof

Info

Publication number: CN106389815A
Application number: CN201610992131.1A
Authority: CN
Inventors: 黄烜
Original assignee: Dongguan Biological Technology Co Ltd
Current assignee: Dongguan Biological Technology Co Ltd
Priority date: 2016-11-11
Filing date: 2016-11-11
Publication date: 2017-02-15

Abstract

The invention discloses a traditional Chinese medicine composition for treating child bronchitis and a preparation method thereof. The traditional Chinese medicine composition is prepared by, by weight, 15-25 parts of tangerine pith, 25-35 parts of prepared pinellia ternate, 25-35 parts of prepared ephedra, 25-35 parts of fructus schizandrae, 45-55 parts of Lilium brownii, 25-35 parts of semen brassicae, 45-55 parts of flos farfarae, 25-35 parts of fritillaria cirrhosa, 45-55 parts of adenophora tetraphylla, 25-35 parts of platycodon grandiflorum, 25-35 parts of oroxylum indicum, 15-25 parts of radix glycyrrhizae, 10-20 parts of asarum, 45-55 parts of folium eriobotryae, 25-35 parts of rhizoma belamcandae, 60-80 parts of cane sugar and 0.001-0.002 part of potassium sorbate. The traditional Chinese medicine composition has effects of ventilating the lung and arresting cough and reducing phlegm and moistening dryness and is capable of solving the relapse problem, definite in curative effect, convenient to use, safe and nontoxic.

Description

A kind of Chinese medicine composition treating infant bronchitis and preparation method

Technical field

The present invention relates to technical field of traditional Chinese medicines, specifically a kind of Chinese medicine composition treating infant bronchitis and preparation side Method.

Background technology

Infant bronchitis mean that bronchus is inflamed, and the pathology of infantile capillary bronchitis occurs mainly in lung Tiny bronchus, that is, capillary bronchus, so name of disease is " bronchiolitis ", typically by common cold, popular The complication that the viral infections such as flu cause is it is also possible to caused by bacterium infection, be the acute upper breathing of the common one kind of children Road infects, and the cause of disease of bronchiolitis is mainly Respiratory Syncytial Virus(RSV), can account for 80% or more；Other is followed successively by adenovirus, Parainfluenza virus, rhinovirus, influenza virus etc.；Minority case can be caused by mycoplasma pneumoniae, after infection virus, tiny capillary Bronchus is congested, oedema, and mucous secretion increases, and adds that the mucomembranous epithelial cell of necrosis comes off and blocks tube chamber, leads to significantly Pulmonary emphysema and atelectasis；Inflammation can involve alveolar, alveolar wall and interstitial lung usually, therefore it is considered that it be pneumonia one kind special Type；Bronchiolitis is different from general tracheitis or bronchitis, clinical symptoms as pneumonia, but based on breathing heavily and suppressing, by Mostly it is to be caused by virus infection in bronchiolitis, therefore morbidity early stage is typically not required to use antibiotic therapy, such as morbidity later stage bosom Antibiotic therapy can be used, treatment it is also possible to treatment by Chinese herbs, is controlled in prior art based on symptomatic treatment during doubtful secondary bacterial infection The Chinese medicine preparation treating infant bronchitis is taken for patient, though having the effect of mitigation symptoms, curative effect is inconspicuous.

Content of the invention

Not enough for prior art, it is an object of the invention to provide a kind of Chinese medicine composition treating infant bronchitis And preparation method, have functions that to declare lung cough-relieving, resolving sputum to moisturize, also solve Problems Concerning Their Recurrence simultaneously, determined curative effect, easy to use, Safety non-toxic.

For solving above technical problem, the technical scheme is that：

A kind of Chinese medicine composition treating infant bronchitis, is made up of the raw material of following weight portion：Tangerine pith 15-25 part, system half Summer 25-35 part, ephedra 25-35 part, fruit of Chinese magnoliavine 25-35 part, lily 45-55 part, semen brassicae 25-35 part, tussilago 45-55 Part, Bulbus Fritillariae Cirrhosae 25-35 part, adenophora tetraphylla 45-55 part, balloonflower root 25-35 part, Oroxylum indicum 25-35 part, Radix Glycyrrhizae 15-25 part, root of Chinese wild ginger 10- 20 parts, loguat leaf 45-55 part, blackberry lily 25-35 part, sucrose 60-80 part, potassium sorbate 0.001-0.002 part；

Its preparation process is：

（1）Raw material tangerine pith, the tuber of pinellia processed, ephedra, the fruit of Chinese magnoliavine, adenophora tetraphylla, balloonflower root, Oroxylum indicum, Radix Glycyrrhizae, the root of Chinese wild ginger, blackberry lily is taken to pulverize, Grinding particle size 30-50 mesh, the raw material after pulverizing is added the water of the 8-10 times amount of its gross weight, decocts 2-3 time, each 20-50 Minute, merge decoction liquor, filter, filtrate stands 12-18 hour, filter, obtain liquid, standby；

（2）Raw material lily, semen brassicae, tussilago, Bulbus Fritillariae Cirrhosae is taken to pulverize, grinding particle size 80-100 mesh, the raw material after pulverizing is added Enter the water of the 8-10 times amount of its gross weight, decoct 2-3 time, each 20-50 minute, merge decoction liquor, filter, filtrate stands 12- 18 hours, filter, obtain liquid, standby；

（3）Gather after fresh loguat leaf is cleaned and 1-2 hour is dried in 55-70 DEG C of drying box, take out, be cooled to room temperature, enter Pot frying, fries to micro- Jiao, has fragrance, be cooled to room temperature, puts into pulverizer, grinding particle size 30-50 mesh, the raw material after pulverizing is added Enter the water of the 8-10 times amount of its weight, decoct 2-3 time, each 20-50 minute, merge decoction liquor, filter, filtrate stands 12-18 Hour, filter, obtain liquid, standby；

（4）By step（1）Middle gained liquid and step（2）Gained liquid, step（3）Middle gained liquid mixing, stirring 15-30 divides Clock, so as to be sufficiently mixed, carries out reduced pressure concentration to liquid, and thickening temperature is 60-65 DEG C, and steam pressure is 0.025- 0.035Mpa, vacuum is 0.065-0.085Mpa, controls relative density of medicine liquid in 1.25-1.35, forms concentration of liquid medicine liquid, standby With；

（5）By step（4）Middle gained concentration of liquid medicine liquid adds the purified water of the 3-6 times amount of weight, adds sucrose and sorbic acid Potassium, is heated to seething with excitement, and micro-boiling rises insulation 10-20 minute, stirs 10-20 minute simultaneously, using centrifugal filtration, is cooled to room temperature, Filling with clear glass bottle, irradiate the sterilizing of 20-40 minute, packaging under uviol lamp, obtain final product the Chinese medicine for the treatment of infant bronchitis Composition.

Preferably, a kind of described Chinese medicine composition treating infant bronchitis, is made up of the raw material of following weight portion： 20 parts of tangerine pith, 30 parts of the tuber of pinellia processed, 30 parts of ephedra, 30 parts of the fruit of Chinese magnoliavine, 50 parts of lily, 30 parts of semen brassicae, 50 parts of tussilago, tendril-leaved fritillary bulb Female 30 parts, 50 parts of adenophora tetraphylla, 30 parts of balloonflower root, 30 parts of Oroxylum indicum, 20 parts of Radix Glycyrrhizae, 15 parts of the root of Chinese wild ginger, 50 parts of loguat leaf, 30 parts of blackberry lily, 70 parts of sucrose, 0.0015 part of potassium sorbate；

Its preparation process is：

（1）Raw material tangerine pith, the tuber of pinellia processed, ephedra, the fruit of Chinese magnoliavine, adenophora tetraphylla, balloonflower root, Oroxylum indicum, Radix Glycyrrhizae, the root of Chinese wild ginger, blackberry lily is taken to pulverize, Grinding particle size 50 mesh, the raw material after pulverizing is added the water of 8 times amount of its gross weight, decocts 2 times, 45 minutes every time, merges and decoct Boil liquid, filters, and filtrate stands 12 hours, filters, obtains liquid, standby；

（2）Raw material lily, semen brassicae, tussilago, Bulbus Fritillariae Cirrhosae is taken to pulverize, grinding particle size 80 mesh, the raw material after pulverizing is added it The water of 8 times amount of gross weight, decocts 2 times, 45 minutes every time, merges decoction liquor, filter, filtrate stands 12 hours, filter, obtain medicine Liquid, standby；

（3）Gather after fresh loguat leaf is cleaned and be dried 1 hour in 55 DEG C of drying box, take out, be cooled to room temperature, enter pot and fry System, fries to micro- Jiao, has fragrance, be cooled to room temperature, puts into pulverizer, grinding particle size 30 mesh, the raw material after pulverizing is added it heavy The water of 8 times amount of amount, decocts 2 times, 35 minutes every time, merges decoction liquor, filter, filtrate stands 12 hours, filter, obtain liquid, Standby；

（4）By step（1）Middle gained liquid and step（2）Gained liquid, step（3）Middle gained liquid mixing, stirs 15 minutes, So that it is sufficiently mixed, reduced pressure concentration is carried out to liquid, thickening temperature is 65 DEG C, steam pressure is 0.025Mpa, vacuum is 0.065Mpa, controls relative density of medicine liquid 1.25, forms concentration of liquid medicine liquid, standby；

（5）By step（4）Middle gained concentration of liquid medicine liquid adds the purified water of 4 times amount of weight, adds sucrose and potassium sorbate, It is heated to seething with excitement, micro-boiling rises insulation 20 minutes, stir 20 minutes simultaneously, using centrifugal filtration, be cooled to room temperature, use cleaned glass Bottle is filling, irradiates sterilizing in 25 minutes, packaging, obtain final product the Chinese medicine composition for the treatment of infant bronchitis under uviol lamp.

Each raw material pharmacological action：

Tangerine pith：Bitter, sweet, mild-natured, returns spleen, lung channel；Effect dredging collateral, preventing phlegm from forming and stopping coughing；Cure mainly for coughing with a lot of sputum, chest side of body is had a pain.

The tuber of pinellia processed：Meridian distribution of property and flavor：Pungent, warm, returns spleen, stomach, lung channel；Indication：Eliminating dampness and eliminating phlegm；For abundant expectoration cough and asthma, phlegm Drink feel dizzy and heart palpitations, anemophlegmatic vertigo, phlegm and headache.

Ephedra：Meridian distribution of property and flavor：Pungent, slight bitter, temperature, return lung, bladder warp；Indication：Sweating dissipates cold, freeings lung and relieving asthma, profit Water is subsided a swelling；For anemofrigid cold, uncomfortable in chest breath with cough, geomantic omen edema；Bronchial astehma；Herba ephedrae moistens the lung and relieve the cough；It is used for table disease Solution, asthma and cough.

The fruit of Chinese magnoliavine：Meridian distribution of property and flavor：Sour, sweet, temperature, return lung, the heart, kidney channel；Indication：Restrain astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney tonifying Calming heart；Breathe heavily for void of coughing long, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, injury thirst, feeble pulse of losing heart, interior heat Quench one's thirst, palpitation and insomnia.

Lily：Meridian distribution of property and flavor：Sweet, tremble with fear, the thoughts of returning home, lung channel；Indication：Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing；Long for the deficiency of Yin Cough, blood-stained sputum, dysphoria palpitates with fear, insomnia and dreamful sleep, absent-minded.

Semen brassicae：Nature and flavor：Odorless, taste is pungent, peppery, return through：The warp of enter liver, spleen, lung, stomach, the heart and collaterals of the uterus；Function：Warm lung is slitted Phlegm profit gas, dissipating bind is removed obstruction in channels to relieve pain；Cure mainly：Reduces phlegm by drink, mass dissipating and swelling eliminating；Main cough and phlegm, fullness in the chest and hypochondriac pain, extremity numbness, joint Swell and ache, multiple abscess with damp phlegm, cloudy subcutaneous ulcer pyogenic infections；Control acute mastitis, breast cancer, mammary gland pain, tuberculosis, phlegm and retained fluid cough and asthma, fullness in chest and hypochondrium pain, gastric disorder causing nausea is vomitted Tell, aphasia from apoplexy, limbs numbness pain is numb, tinea pedis, cloudy subcutaneous ulcer, pyogenic infections, treating swelling and pain by traumatic injury.

Tussilago：Meridian distribution of property and flavor：Pungent, slight bitter, temperature, return lung warp；Indication：Moistening lung to lower qi is relieving cough and reducing sputum；For newly long Cough, dyspnea and cough with excessive sputum, labor is coughed hemoptysis.

Bulbus Fritillariae Cirrhosae：Meridian distribution of property and flavor：Bitter, sweet, it is slightly cold, return lung, the heart channel of Hang-Shaoyin；Indication：Clearing heat and moistening lung, preventing phlegm from forming and stopping coughing；For Lung-heat type cough, the few phlegm of dry cough, deficiency of Yin labor is coughed, and coughs up sputum streaked with blood.

Adenophora tetraphylla：Nature and flavor, sweet, slight bitter, cold nature, return through, return lung, stomach；Indication：Replenishing the vital essence and removing heat, moistening lung Phlegm, reinforcing stomach reg fluid, main yin chronic cough, consumptive disease is coughed phlegm blood, and cough caused by dryness phlegm is few, abnormal heat larynx numbness, injury thirst.

Balloonflower root：Meridian distribution of property and flavor：Bitter, pungent, put down, return lung warp；Indication：A surname's lung, profit pharynx, eliminating the phlegm, apocenosis；For phlegm of coughing Many, uncomfortable in chest not smooth, pharyngalgia, sound is mute, lung carbuncle pyemesis, and sore purulence becomes not burst.

Oroxylum indicum：Meridian distribution of property and flavor：Bitter, sweet, cool, return lung, liver, stomach；Indication：Removing heat from the lung and relieving sorethroat, soothing liver and harmonizing stomach；For Cough with lung heat, larynx numbness, sound is mute, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.

Radix Glycyrrhizae：Mild-natured, sweet, the thoughts of returning home, spleen, lung, stomach；Effect：Help；Indication：Invigorate the spleen and benefit qi, clearing heat and detoxicating, Expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription；For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs Contraction urgency pain, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.

The root of Chinese wild ginger：Meridian distribution of property and flavor：Pungent, temperature, the thoughts of returning home, lung, kidney channel；Indication：Expelling wind and clearing away cold, sensible pain relieving, Wenfei of drink； For anemofrigid cold, have a headache, toothache, nasosinusitis of having a stuffy nose, arthralgia due to wind-dampness, phlegm and retained fluid is breathed with cough.

Loguat leaf：Meridian distribution of property and flavor：Hardship, is slightly cold, and attaches to the lung and stomach meridians；Indication：Removing heat from the lung to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI；For lung heat Cough, the circulation of vital energy in the wrong direction breathes heavily urgency, and stomach energy is vomitted inverse, dysphoria and thirsty.

Blackberry lily：Meridian distribution of property and flavor：Hardship, trembles with fear, return lung warp；Indication：Clearing heat and detoxicating, dissolving phlegm, profit pharynx；Strongly fragrant for heat toxin convulsive seizure due to phlegm-fire Knot, abscess of throat, accumulation and obstruction of sputum, cough and asthma.

Beneficial effects of the present invention：Have functions that to declare lung cough-relieving, resolving sputum to moisturize, also solve Problems Concerning Their Recurrence, curative effect simultaneously Definitely, easy to use, safe nontoxic.

Specific embodiment

With reference to embodiment, the invention will be further described.

Embodiment 1

A kind of Chinese medicine composition treating infant bronchitis, is made up of the raw material of following weight portion：25 parts of tangerine pith, the tuber of pinellia processed 35 Part, 35 parts of ephedra, 35 parts of the fruit of Chinese magnoliavine, 55 parts of lily, 35 parts of semen brassicae, 55 parts of tussilago, 35 parts of Bulbus Fritillariae Cirrhosae, adenophora tetraphylla 55 Part, 35 parts of balloonflower root, 35 parts of Oroxylum indicum, 25 parts of Radix Glycyrrhizae, 20 parts of the root of Chinese wild ginger, 55 parts of loguat leaf, 35 parts of blackberry lily, 80 parts of sucrose, sorbic acid 0.002 part of potassium；

Its preparation process is：

Usage：Oral, 3 times a day, each 5ml.

Embodiment 2

A kind of Chinese medicine composition treating infant bronchitis, is made up of the raw material of following weight portion：20 parts of tangerine pith, the tuber of pinellia processed 30 Part, 30 parts of ephedra, 30 parts of the fruit of Chinese magnoliavine, 50 parts of lily, 30 parts of semen brassicae, 50 parts of tussilago, 30 parts of Bulbus Fritillariae Cirrhosae, adenophora tetraphylla 50 Part, 30 parts of balloonflower root, 30 parts of Oroxylum indicum, 20 parts of Radix Glycyrrhizae, 15 parts of the root of Chinese wild ginger, 50 parts of loguat leaf, 30 parts of blackberry lily, 70 parts of sucrose, sorbic acid 0.0015 part of potassium；

Its preparation process is：

Usage：Oral, 3 times a day, each 5ml.

Embodiment 3

A kind of Chinese medicine composition treating infant bronchitis, is made up of the raw material of following weight portion：15 parts of tangerine pith, the tuber of pinellia processed 25 Part, 25 parts of ephedra, 25 parts of the fruit of Chinese magnoliavine, 45 parts of lily, 25 parts of semen brassicae, 45 parts of tussilago, 25 parts of Bulbus Fritillariae Cirrhosae, adenophora tetraphylla 45 Part, 25 parts of balloonflower root, 25 parts of Oroxylum indicum, 15 parts of Radix Glycyrrhizae, 10 parts of the root of Chinese wild ginger, 45 parts of loguat leaf, 25 parts of blackberry lily, 60 parts of sucrose, sorbic acid 0.001 part of potassium；

Its preparation process is：

Usage：Oral, 3 times a day, each 5ml.

Traditional Chinese medicine composition for treating of the present invention observes infant bronchitis patient 50, and clinical report is as follows：

1st, physical data

Clinical observation infant bronchitis patient 50, the wherein male sex 30, women 20,8 months to 6 years old age.

2nd, diagnostic criteria

1. cough due to wind-heat evil's type：Expectoration is not well, yellow and sticky sputum, thirsty pharyngalgia, turbid nasal discharge, fever and headache, has sweat, the micro- Huang of tongue fur, Superficial and rapid pulse；

2. hot phlegm stops up pulmonary type：Coughing with a lot of sputum, sticky difficulty brings up, flushing of generating heat, and hot eyes lip is red, haves the fidgets, and urine is yellow few, stool It is dried, yellow tongue fur, slippery and rapid pulse.

3rd, treatment method

Using traditional Chinese medicine composition for treating of the present invention, take traditional Chinese medicine oral liquid of the present invention, 3 times a day, each 5ml, 4 days is a treatment Journey.

4th, curative effect determinate standard

Cure：Symptom disappears；

Take a turn for the better：Clinical symptom relief；

Invalid：Clinical symptoms are no improved or are increased.

5th, treatment results

In clinical treatment infant bronchitis patient 50, cure 40 and account for 80%, taking a turn for the better 10 accounts for 20%, invalid 0, always effectively Rate is 100%.

6th, model case

Case 1：Man, 3.5 years old, infant tracheitis, cough phlegm is yellow, be difficult expectoration, thirsty, heating, sweating, arteries and veins number, yellow tongue fur matter are red, Take one course for the treatment of of Chinese medicine preparation of the present invention, patient symptom is clearly better, take one course for the treatment of of Chinese medicine preparation of the present invention again, clinical Cure.

Case 2：Female, 2.5 years old, infant tracheitis, cough, last one month, coughing with a lot of sputum, sticky difficulty brings up, and generate heat face Red, hot eyes lip is red, haves the fidgets, and urine is yellow few, is hard and dry, yellow tongue fur, slippery and rapid pulse, takes one treatment of Chinese medicine preparation of the present invention Journey, patient symptom is clearly better, and takes one course for the treatment of of Chinese medicine preparation of the present invention, clinical cure again.

Case 3：Female, 2 years old, infant tracheitis, cough, last two months, coughing with a lot of sputum, sticky difficulty brings up, flushing of generating heat, Hot eyes lip is red, haves the fidgets, and urine is yellow few, is hard and dry, yellow tongue fur, and slippery and rapid pulse takes one course for the treatment of of Chinese medicine preparation of the present invention, disease People's symptom is clearly better, and takes one course for the treatment of of Chinese medicine preparation of the present invention, clinical cure again.

Above the present invention is described in detail, the explanation of embodiment be only intended to help understand the method for the present invention and Its core concept, its object is to allow the personage being familiar with this art will appreciate that present disclosure and to implement according to this, and Can not be limited the scope of the invention with this；All equivalence changes made according to spirit of the invention or modification, all should contain Cover within protection scope of the present invention.

Claims

1. a kind of Chinese medicine composition treating infant bronchitis it is characterised in that：It is made up of the raw material of following weight portion：Tangerine pith 15-25 part, tuber of pinellia 25-35 part processed, ephedra 25-35 part, fruit of Chinese magnoliavine 25-35 part, lily 45-55 part, semen brassicae 25-35 part, Tussilago 45-55 part, Bulbus Fritillariae Cirrhosae 25-35 part, adenophora tetraphylla 45-55 part, balloonflower root 25-35 part, Oroxylum indicum 25-35 part, Radix Glycyrrhizae 15-25 Part, root of Chinese wild ginger 10-20 part, loguat leaf 45-55 part, blackberry lily 25-35 part, sucrose 60-80 part, potassium sorbate 0.001-0.002 part.

2. the preparation method of a kind of Chinese medicine composition treating infant bronchitis according to claim 1, its feature exists In：Its preparation process is：

3. the preparation method of a kind of Chinese medicine composition treating infant bronchitis according to claim 2, its feature exists In：Its preparation process is：

4. a kind of Chinese medicine composition treating infant bronchitis according to claim 1 it is characterised in that：By following heavy The raw material of amount part is made：20 parts of tangerine pith, 30 parts of the tuber of pinellia processed, 30 parts of ephedra, 30 parts of the fruit of Chinese magnoliavine, 50 parts of lily, 30 parts of semen brassicae, 50 parts of tussilago, 30 parts of Bulbus Fritillariae Cirrhosae, 50 parts of adenophora tetraphylla, 30 parts of balloonflower root, 30 parts of Oroxylum indicum, 20 parts of Radix Glycyrrhizae, 15 parts of the root of Chinese wild ginger, loguat leaf 50 parts, 30 parts of blackberry lily, 70 parts of sucrose, 0.0015 part of potassium sorbate.

5. a kind of Chinese medicine composition treating infant bronchitis according to claim 1 it is characterised in that：By following heavy The raw material of amount part is made：25 parts of tangerine pith, 35 parts of the tuber of pinellia processed, 35 parts of ephedra, 35 parts of the fruit of Chinese magnoliavine, 55 parts of lily, 35 parts of semen brassicae, 55 parts of tussilago, 35 parts of Bulbus Fritillariae Cirrhosae, 55 parts of adenophora tetraphylla, 35 parts of balloonflower root, 35 parts of Oroxylum indicum, 25 parts of Radix Glycyrrhizae, 20 parts of the root of Chinese wild ginger, loguat leaf 55 parts, 35 parts of blackberry lily, 80 parts of sucrose, 0.002 part of potassium sorbate.

6. a kind of Chinese medicine composition treating infant bronchitis according to claim 1 it is characterised in that：By following heavy The raw material of amount part is made：15 parts of tangerine pith, 25 parts of the tuber of pinellia processed, 25 parts of ephedra, 25 parts of the fruit of Chinese magnoliavine, 45 parts of lily, 25 parts of semen brassicae, 45 parts of tussilago, 25 parts of Bulbus Fritillariae Cirrhosae, 45 parts of adenophora tetraphylla, 25 parts of balloonflower root, 25 parts of Oroxylum indicum, 15 parts of Radix Glycyrrhizae, 10 parts of the root of Chinese wild ginger, loguat leaf 45 parts, 25 parts of blackberry lily, 60 parts of sucrose, 0.001 part of potassium sorbate.