CN106389704A - 一种治疗甲癣的药油及其制备方法 - Google Patents
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Abstract
本发明涉及一种治疗甲癣的中药药油及其制备方法,它是由下述重量配比原料组成:白头翁100一10份,黄芩100一10份,丁香100一10份,皂荚100一10份,蜈蚣100一10份,藿香100一10份,射干100一10份、桂枝100一10份,乌梅100一10份,甘油4500一350份。制备方法是:将上述药物磨成粗末,入甘油中浸泡后,滤除药渣,留滤液。效果:临床治疗86例,治愈65例,好转21例。
Description
技术领域
本发明涉及一种药油,具体为治疗甲癣的中药药油及其制备方法。
背景技术
甲癣是常见多发皮肤病,由浅部真菌侵犯甲板或甲下所发,初起时在指、趾甲的远端、侧缘,有的在半月形处,发现指、趾甲变色、变形,失去光泽,逐渐蛀空,增厚变脆,呈灰白、褐色,或污秽色,高低不平,残缺不全,呈畸形状态。有的前端蛀空,向后发展,使部分或整个甲板与甲床分离,破坏程度因人而异,各个指、趾甲也不一样。
西药治疗此病,口服斯皮仁诺,外用冰醋酸、复方土槿皮酊、水杨酸酒精。但服药对胃肠、肝、肾可造成损伤。外用药刺激性大,易引起严重指、趾甲周围炎症。达克宁霜、克霉唑乳膏,患者反应用后效果亦不明显。
发明内容
本发明目的:为使患者甲癣较快消退,恢复正常指趾甲色泽,本药是以纯中草药配伍,制成油剂,达到杀灭霉菌,保护指趾甲作用及目的。
本发明是这样实现的:一种治疗甲癣的药油,它是由下述重量配比原料组成:白头翁100一10份,黄芩100一10份,丁香100一10份,皂荚100一10份,蜈蚣100一10份,藿香100一10份,射干100一10份、桂枝100一10份,乌梅100一10份,甘油4500一350份。
本发明所述的一种治疗甲癣的药油最佳配比范围是:白头翁20份,黄芩20份,丁香20份,皂荚20份、蜈蚣20份,藿香20份,射干20份,桂枝20份,乌梅20份,甘油700份。
本发明所述药油制备方法是:将白头翁、黄芩、丁香、皂荚、蜈蚣、藿香、射干、桂枝、乌梅,磨成粗末,入甘油中浸泡10日,然后滤除药渣,所剩滤液即为治疗甲癣的药油,分装塑料瓶中备用。
本发明的用药依据是:白头翁,味苦,性寒,现代研究,含白头翁素、皂甙,对多种真菌有杀灭作用;黄芩,味苦,性寒。含黄芩素,贝加因、黄芩宁,对多种皮肤真菌有抑制作用;丁香,味辛,性温。对多种皮肤真菌有抗菌作用,且疗效显著;皂荚,味辛、咸,性温。含白单甙,对多种皮肤真菌有较好抑制作用;蜈蚣,味辛,性温。对皮肤癣菌有抗菌功效;藿香,味辛,微温。含藿香油、苯甲醛、丁香油酚、桂皮醛等,对多种真菌有抑制作用;射干,味苦,性寒。对致病性真菌有抑制作用;桂枝,味辛、甘,性温。含桂皮油、桂皮醛、桂皮乙酸脂,对皮肤癣菌有抑制作用;乌梅,味酸、涩,性平。含有机酸,具有抗真菌作用。甘油做为基质浸泡上述中药后,药效尽在其中,搽于患处,杀灭真菌,功专力宏。
本发明的有益效果是:临床中结过治疗观察对甲癣效果比较显著,因是纯中药油剂,不仅杀灭真菌,对病变指、趾甲能起到软化作用,并且可促进药油吸收,药效不易挥发,无任何刺激性,且对甲有保护作用。患者均愿接受,与西药外用相比,具一定优越性。应坚持用药,不可间断,致指、趾甲恢复正常。
药油的使用方法:每日6次棉签蘸搽病甲处,直至指、趾甲恢复正常。注:治疗前最好经常先用指甲刀将增后残缺不平的甲削削,然后再搽药油,治疗效果更快更好。
临床治疗观察
临床治疗86例,男49例,女37例,年龄30一71岁。其中手指甲27例,足趾甲59例。所有病例均符合甲癣的诊断标准,真菌镜检阳性。
治疗效果:参照中医病证诊断疗效标准中灰指甲诊断依据。治愈:病甲全部脱落,新生甲色泽正常,真菌镜检阴性。好转:病甲脱落30%以上。未愈:病甲未脱或脱落不足30%,复查真菌阳性。经治疗40天后进行疗效统计,结果86例中,治愈65例,好转21例。
具体实施方式
下面用具体实施例来说明本发明的技术特征
实施例一:白头翁50g,黄芩50g,丁香50g,皂荚50g,蜈蚣50g,藿香50g,射干50g,桂枝50g,乌梅50g,甘油2000ml。
该药油的制备方法是:将白头翁、黄芩、丁香、皂荚、蜈蚣、藿香、射干、桂枝、乌梅,磨成粗末,入甘油中浸泡10日,然后滤除药渣,所剩滤液即为治疗甲癣的药油,分装塑料瓶中备用。
实施例二:白头翁70g,黄芩70g,丁香70g,皂荚70g,蜈蚣70g,藿香70g,射干70g,桂枝70g,乌梅70g,甘油2900ml。
实施例三:白头翁20g,黄芩20g,丁香20g,皂荚20g,蜈蚣20g,藿香20g,射干20g,桂枝20g,乌梅20g,甘油700ml。
该药油的制备方法按上述实施例一制备工艺加工即可。
从实践中对3个实施例方案进行了疗效比较,认为实施例3疗效优于实施例1、实施例2,所以实施例3为最佳实施例,临床治疗效果好。
Claims (3)
1.一种治疗甲癣的药油,其特征是由下述重量配比原料组成:白头翁100一10份,黄芩100一10份,丁香100一10份,皂荚100一10份,蜈蚣100一10份,藿香100一10份,射干100一10份、桂枝100一10份,乌梅100一10份,甘油4500一350份。
2.如权利要求1所述的一种治疗甲癣的药油,其特征是由下述重量配比原料组成:白头翁20份,黄芩20份,丁香20份,皂荚20份、蜈蚣20份,藿香20份,射干20份,桂枝20份,乌梅20份,甘油700份。
3.一种治疗甲癣的药油制备方法,其特征在于包括如下步骤:将白头翁、黄芩、丁香、皂荚、蜈蚣、藿香、射干、桂枝、乌梅,磨成粗末,入甘油中浸泡不小于10日,然后滤除药渣,所剩滤液即为治疗甲癣的药油,分装备用。
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CN107596050A (zh) * | 2017-11-07 | 2018-01-19 | 翁玉斐 | 一种治疗灰指甲的药物 |
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CN105125939A (zh) * | 2015-09-29 | 2015-12-09 | 湖北中医药大学 | 治疗真菌性皮肤病的中药外用制剂及其制备方法和应用 |
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CN105125939A (zh) * | 2015-09-29 | 2015-12-09 | 湖北中医药大学 | 治疗真菌性皮肤病的中药外用制剂及其制备方法和应用 |
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Title |
---|
宋立人等主编: "《现代中药学大辞典(上、下册)》", 31 May 2001, 人民卫生出版社 * |
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