CN1063641C - Chinese medicinal preparation for treatment of toothache - Google Patents
Chinese medicinal preparation for treatment of toothache Download PDFInfo
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- CN1063641C CN1063641C CN96100397A CN96100397A CN1063641C CN 1063641 C CN1063641 C CN 1063641C CN 96100397 A CN96100397 A CN 96100397A CN 96100397 A CN96100397 A CN 96100397A CN 1063641 C CN1063641 C CN 1063641C
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Abstract
The present invention relates to a pure Chinese medicinal preparation formed by preparing and processing root of parker raspberry and radix isatidis which are used as main raw material, and auxiliary material. The present invention is used for treating oral diseases such as gastropyretic toothache, gumline gall, tooth space apostasis, periodontitis, throat gall, stomatitis, etc., has an obvious curative effect on all the diseases, has an inhibitory effect on various pathogenic bacteria which invade oral cavities, and has the characteristics of fast effects, good curative effects, small dosage, no medicine flavor of the traditional Chinese medicine, good mouth feel, convenient administration and no toxic and side effects.
Description
The present invention relates to treat the medicine of toothache, being specially with the pure natural medical plant is the Chinese medicine preparation of raw material processing preparation.
Toothache is a kind of commonly encountered diseases that is difficult to cure and frequently-occurring disease, the Western medicine of clinical practice at present has antipyretic analgesic (as somedon, dipyrone, concurrent heating breath pain, aspirin, Alysine (Marion Merrell Dow) etc.) and anaerobe resistant class medicine, peaceful etc. as the peace of having a toothache, periodontal health, periodontal) though can of short duration pain relieving, but can not effect a radical cure, too much take, certain side effect is all arranged.All kinds of antiinflammatory that wet one's whistle of sucking in the Chinese patent medicine have certain curative effect as four seasons throat lozenge, cow-bezoar anti-toxic bolus, Rhizoma Coptidis shangqing pill, Herba Pileae Scriptae Tabellae, Waterelon Frost Lozenges, cydiodine etc. to the bottleneck throat inflammation, but not obvious to the periodontal disease effect.Therefore have not yet to see and be used for the treatment of the sick comparatively ideal medicine of toothache.
Purpose of the present invention, providing a kind of is that raw material is processed into to have conveniently and takes with the pure natural medical plant, therapeutic effect is obvious, and the Chinese medicine preparation of treatment without any side effects toothache.
The medicine of treatment toothache of the present invention, having selected pure natural medical plant Radix Rubi Parkeri and Radix Isatidis for use is the Chinese medicine preparation that primary raw material prescription and adjuvant are processed into, the composition % (g/g) of its primary raw material:
Radix Rubi Parkeri 70～80
The best of Radix Isatidis 20～30 its primary raw materials is formed % (g/g)
Radix Rubi Parkeri 75
Radix Isatidis 25
Described Radix Rubi Parkeri is meant and digs the biennial above Radix Rubi Parkeri root that digs after the annual early spring or the Autumnal Equinox, clean earth, the Yu Yin air dried medical material in ventilation that dries in the air.Its concrete making step is: the Radix Rubi Parkeri of getting cleaned airing, the Radix Isatidis of thinly slicing and thinly slicing, with above-mentioned prescription batching, the clear water that adds 30 minutes (weight) by per 1 minute (weight) mixing spice decocted 1.5 hours, filter time drug extract of winning; Medicinal residues the are added 10 fens clear water of (by former mixing spice weight) repeats to decoct secondary again, and each 30 minutes, filter, abandon medicinal residues; Three drug extracts are merged, and be condensed into former dose 30% (g/g) extractum shape medicine; With powdered sugar thin with the back oven dry that stirs of extractum shape medicine, vibration screening is single-size shape electuary, also available spray drying technology or the spraying freeze drying technology of ventilating is produced, and carries out packing then.Promptly be processed into the graininess electuary that clinically to take.Electuary water content 3-4% (g/g), medicine effective content are 24～25% (g/g).
The method that the drug extract or the extractum shape medicine of above-mentioned prescription are made oral liquid routinely can be processed into oral liquid formulations, its Chinese medicine effective content 3.6%～3.75% (g/mL).
Also the drug extract of above-mentioned prescription can be added adjuvant, make the method for lamellar dosage form, be processed into buccal tablet by the normalizing regulation.Its Chinese medicine effective content is 29～30% (g/g)
The Chinese medicine preparation of the treatment toothache of the electuary of being processed as with above-mentioned medicine material prescription and auxiliary material, oral liquid, buccal tablet is treated all kinds of toothache and oral disease through clinical practice.Electuary: each 15g, every day three times; Oral liquid: each 50mL, every day 4～6 times; Buccal tablet: every 50mg, each 2-4 sheet, be 1～6 day the general course of treatment, all has than obvious treatment effect (subordinate list 1); Especially treat toothache due to stomach-fire, periodontitis, its effective percentage are all more than 98%, and cure rate reaches more than 89%; And can effect a radical cure, no longer recurrence also can be treated oral diseases such as pharyngalgia pharyngitis, oral ulcer, stomatitis simultaneously, and better effects is all arranged.That this Chinese medicine preparation has is rapid-action, good effect, little, the no Chinese medicine flavor of dosage, mouthfeel are good, be convenient to take, characteristics without any side effects, and the general effect of its treatment toothache and oral disease is better than similar medicine.The Chinese medicine electuary curative effect statistics of table 1 treatment toothache of the present invention
| The sick kind | The example number | Cure | Produce effects | Effectively | Invalid | Control Yu and lead (%) | Effective percentage (%) |
| Toothache due to stomach-fire | 338 | 326 | 2 | 1 | 0 | 96.49 | 100 |
| The gingiva periodontitis | 182 | 162 | 14 | 3 | 3 | 89 | 98.35 |
| The teeth groove abscess | 33 | 23 | 5 | 3 | 2 | 69.69 | 93.93 |
| The pharyngalgia pharyngitis | 71 | 65 | 2 | 2 | 0 | 91.54 | 100 |
| The oral ulcer stomatitis | 25 | 20 | 3 | 2 | 6 | 60 | 80 |
| Toothache due to dental caries | 119 | 48 | 30 | 13 | 18 | 40.33 | 84.87 |
| The gingival hemorrhage redness | 11 | 6 | 2 | 1 | 2 | 54.54 | 81.81 |
| The gingiva trigeminal neuralgia | 21 | 8 | 4 | 4 | 5 | 38.09 | 76.19 |
Illustrate: this table statistical content is the result of 1987.6～1994.12.30 clinic trial
* Radix Rubi Parkeri is meant and is distributed in a kind of perennial woody plant that the Southwest China area spreads all over hill within the border, it is characterized in that: the early spring is when germinateing, the time limit take on a red color, the Ye Kuo garden, blade back is covered with tenderly white fine hair, the blade face green, the thick shape greening of petiole, burr is brownish red.The ground multi-branched, the high about 60～100cm of branch does not have flower, has no result, and the foundation thickness does not wait, multifilament, the root bark color is brown.
Example 1
Raw material:
Radix Rubi Parkeri: select for use dig the early spring and dig the also domestic biennial Radix Rubi Parkeri in father-in-law An County, Guizhou Province of airing, thinly slice, take by weighing 750g; Radix Isatidis after drying is thinly sliced, and takes by weighing 250kg.
Radix Rubi Parkeri, the Radix Isatidis of above-mentioned amount are mixed in stainless-steel pan, add the free of contamination clear water of 30kg, decoct after 1.5 hours, filter, keep medicinal liquid; With the medicinal residues after filtering, add 10kg water, decocted 30 minutes for the second time, filter, keep medicinal liquid for the second time, again medicinal residues are added 10kg water, decocted for the third time 30 minutes, and filtered, obtain medicinal liquid for the third time, three mixed drug extracts of medicinal liquid are concentrated, up to the extractum shape medicine that obtains 300g.Add powder castor sugar 450g in extractum, stir and do baking after 4 hours down at 40～45 ℃, vibration screening (3
#Sieve), make the electuary preparation of single-size shape.Water content is 4% (g/g) in the preparation, and the effective content of medicine is 24% (g/g).And pack by every bag 15g.
Example 2
Material medicine prescription batching and operating procedure make the 300g drug extract with example 1, add 3.5kg clear water, 2kg white sugar, boil 10 minutes, carry out fill with every and 50mL, make oral liquid.The medicine effective content is 3.7% (g/mL)
Example 3
Material medicine prescription batching, after operating procedure makes the 300g drug extract with example 1, add the 310g white sugar, 52g starch, stir, place square position (rustless steel) in 50 ℃-55 ℃ oven dry down, about 8 hours, water content 1%, powder is thin, use the tablet machine tabletting, every 50mg medicine effective content 29% (g/g) is made buccal tablet.
Claims (5)
1, a kind of medicine for the treatment of toothache is characterized in that with pure natural medical plant Radix Rubi Parkeri, Radix Isatidis be the Chinese medicine preparation that primary raw material and adjuvant are processed as, and the composition % (g/g) of described primary raw material is:
Radix Rubi Parkeri 70～80
Radix Isatidis 20～30.
2, the medicine of treatment toothache as claimed in claim 1 is characterized in that the composition % (g/g) of described primary raw material is:
Radix Rubi Parkeri 75
Radix Isatidis 25.
3, the medicine of treatment toothache as claimed in claim 1 or 2 is characterized in that described Chinese medicine preparation is an electuary.
4, the medicine of treatment toothache as claimed in claim 1 or 2 is characterized in that described Chinese medicine preparation is an oral liquid.
5, the medicine of treatment toothache as claimed in claim 1 or 2 is characterized in that described Chinese medicine preparation is a buccal tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96100397A CN1063641C (en) | 1996-01-18 | 1996-01-18 | Chinese medicinal preparation for treatment of toothache |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96100397A CN1063641C (en) | 1996-01-18 | 1996-01-18 | Chinese medicinal preparation for treatment of toothache |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1135347A CN1135347A (en) | 1996-11-13 |
| CN1063641C true CN1063641C (en) | 2001-03-28 |
Family
ID=5116590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96100397A Expired - Fee Related CN1063641C (en) | 1996-01-18 | 1996-01-18 | Chinese medicinal preparation for treatment of toothache |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1063641C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1301730C (en) * | 2004-11-06 | 2007-02-28 | 邓元文 | Medicine for treating decayed tooth and toothache |
| CN101327266B (en) * | 2008-07-18 | 2011-09-14 | 南方医科大学 | Oral cavity nursing agent for preventing and treating oral disease induced by Helicobacter pylori infection contamination |
| CN101978995A (en) * | 2010-10-26 | 2011-02-23 | 长治市郊区人民医院 | Medicament for treating toothache |
| CN108378259A (en) * | 2018-05-03 | 2018-08-10 | 荆楚理工学院 | A kind of Wu Pao for clearing heat and removing internal heat treatment ulcer of mouth-tongue life sore reduces internal heat beverage |
-
1996
- 1996-01-18 CN CN96100397A patent/CN1063641C/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| 1989,9(2) 1989.1.1 * |
| 口腔医学1989,9(2) 1989.01.01 曾光明等 口炎宁冲剂治疗急性牙源性炎症的临床研究 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1135347A (en) | 1996-11-13 |
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