CN106362059A - Traditional Chinese medicine preparation for treating hemorrhoids and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating hemorrhoids and preparation method thereof Download PDFInfo
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- CN106362059A CN106362059A CN201610992024.9A CN201610992024A CN106362059A CN 106362059 A CN106362059 A CN 106362059A CN 201610992024 A CN201610992024 A CN 201610992024A CN 106362059 A CN106362059 A CN 106362059A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating hemorrhoids and a preparation method thereof. The traditional Chinese medicine preparation for treating hemorrhoids is prepared from the following raw materials in parts by weight: 120-180 parts of radix salviae miltiorrhizae, 120-180 parts of rhizoma alismatis, 120-180 parts of ganoderma lucidum, 120-180 parts of raspberry, 120-180 parts of cherokee rose, 120-180 parts of Semen Euryales, 120-180 parts of mulberry seed, 120-180 parts of glossy privet fruit, 70-130 parts of Rhodiola rosea, 90-150 parts of wolfberry fruit, 170-230 radix psuedostellariae, 170-230 parts of sophora fruit, 70-130 parts of cortex pseudolaricis, 170-230 parts of stemona, 120-180 parts of angelica, 120-180 parts of cicada ecdysis, 120-180 parts of radix sileris, 120-180 parts of herba schizonepetae, 120-180 parts of radix scutellariae, 0.001-0.002 part of aspartame and 0.001-0.002 part of sodium benzoate. The traditional Chinese medicine preparation has the effects of clearing away heat to stop bleeding, nourishing yin and purging the pathogenic fire, has obvious drug effects, can be taken for a long time, and can be easily accepted by the patients.
Description
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of Chinese medicine preparation treating hemorrhoid and preparation method.
Background technology
Hemorrhoid, being commonly called as hemorrhoid is a kind of common disease positioned at anus area, and any age all can fall ill, but increases with the age
Long, sickness rate is gradually increased, and in China, hemorrhoid are modal anal and intestinal diseases, and in the U.S., the sickness rate of hemorrhoid is about 5%, and the cause of disease is closed
The cause of disease in hemorrhoid mainly has two kinds of theories, is varicose vein theory first it is believed that hemorrhoid are under distal rectal mucosa and anal canal skin
Under venous plexuses congestion, the venous group that formed of expansion and flexing, but well accepted theory is the anus pad of thomson at present
Move down theory it is believed that hemorrhoid script is the normal anatomical structure in anal canal position, i.e. blood vessel pad, is pectinate line and the ring of above 1.5cm
When shape cavernous transformation taeniae telarum, only anus pad tissue occurs exception and is associated with symptom, hemorrhoid could be referred to as, just need to treat, treatment
Purpose is to release symptom, and non-elimination hemorrhoid body, and the risk factor of hemorrhoid is a lot, wherein constipation, long-term alcohol, a large amount of zests of taking food
Food and sitting standing for a long time are main inducing, and classification hemorrhoid are divided into internal hemorrhoid, external hemorrhoid, mixed hemorrhoid by the difference of happening part, in anal canal skin
There is a jagged visible line junction of skin and rectal mucosa anal canal pectinate line, more than pectinate line for internal hemorrhoid,
It is support structures, venous plexuses and arteriovenous anastomosis Zhi Fasheng pathological change or the displacement of anus pad, coating rectal mucosa, included due to interior
About flesh shrinks, and anus pad is divided into left side, forward right side, three pieces of right lateral side with y type ditch, and therefore internal hemorrhoid is common in left side, forward right side and the right side
Rear side；It is external hemorrhoid below pectinate line, coating anal canal mucosa, connective tissue external hemorrhoid, varicose external hemorrhoid, thrombosis can be divided into
Property external hemorrhoid；Have concurrently internal hemorrhoid and external hemorrhoid for mixed hemorrhoid, be that internal hemorrhoid is passed through venous plexuses and merged with corresponding external hemorrhoid, i.e. upper and lower vein
The coincideing of clump, outside mixed hemorrhoid abjection anus, during in plum blossom-shaped, referred to as annular hemorrhoid, if by sphincter incarceration, form strangulated hemorrhoid；
At present, Chinese medicine hemorrhoid research report is increasing, because its Small side effects is accepted by vast hemorrhoid patients, using existing
For scientific equipment and method, inquire into hemorrhoid etiology and pathogenesis, screening verification active drug, develop with strong points, curative effect affirmative, dosage form
Easy Chinese medicine preparation, is key issue currently urgently to be resolved hurrily.
Content of the invention
For solving above-mentioned technical problem, the present invention provides a kind of Chinese medicine preparation treating hemorrhoid, former by following weight portion
Material is made: Radix Rehmanniae 120-180 part, Radix Salviae Miltiorrhizae 120-180 part, Rhizoma Alismatis 120-180 part, Ganoderma 120-180 part, Fructus Rubi 120-
180 parts, Fructus Rosae Laevigatae 120-180 part, Semen Euryaless 120-180 part, Fructus Mori 120-180 part, Fructus Ligustri Lucidi 120-180 part, Radix Rhodiolae 70-
130 parts, Fructus Lycii 90-150 part, Radix Pseudostellariae 170-230 part, Fructus Sophorae 170-230 part, Cortex Pseudolaricis 70-130 part, Radix Stemonae 170-230
Part, Radix Angelicae Dahuricae 120-180 part, Periostracum Cicadae 120-180 part, Radix Saposhnikoviae 120-180 part, Herba Schizonepetae 120-180 part, Radix Scutellariae 120-180 part, A Si
Ba Tian 0.001-0.002 part, sodium benzoate 0.001-0.002 part；
The present invention also provides a kind of preparation method of the Chinese medicine preparation treating hemorrhoid, and its preparation process is:
(1) take raw material Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Ganoderma, Fructus Rubi, Fructus Rosae Laevigatae to put into pulverizer to pulverize, cross 80-100 mesh sieve,
Obtain raw material powder, standby；
(2) take raw material Semen Euryaless, Fructus Mori, Fructus Ligustri Lucidi, Radix Rhodiolae, Fructus Lycii, Radix Pseudostellariae to put into pulverizer to pulverize, cross 50-60 mesh
Sieve, obtains raw material powder, standby；
(3) take the raw material Fructus Sophorae, Cortex Pseudolaricis, the Radix Stemonae, the Radix Angelicae Dahuricae, Periostracum Cicadae, Radix Saposhnikoviae, Herba Schizonepetae, Radix Scutellariae to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
(4) step (1) gained raw material powder and step (2) gained raw material powder and (3) gained raw material powder are added water to cook twice, first
The secondary water adding raw material weight 10-12 times amount, decocts 0.4-1 hour, pours out medicinal liquid, the water that second adds raw material weight 6-8 times amount,
Decoct 0.4-1 hour, merge medicinal liquid twice, filter, filtrate is concentrated into 55-60 DEG C and surveys the clear paste that relative density is 1.08-1.15,
Plus the appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filter, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
(5) raw material aspartame, sodium benzoate is taken to be dissolved into respectively in water, standby；
(6) step (4) gained thick paste is added the pure water of its weight 3-5 times amount, add the aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, cold preservation,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of hemorrhoid.
Preferably in scheme, a kind of Chinese medicine preparation treating hemorrhoid, it is made up of the raw material of following weight portion: Radix Rehmanniae 150
Part, 150 parts of Radix Salviae Miltiorrhizae, 150 parts of Rhizoma Alismatis, 150 parts of Ganoderma, 150 parts of Fructus Rubi, 150 parts of Fructus Rosae Laevigatae, 150 parts of Semen Euryaless, Fructus Mori 150
Part, 150 parts of Fructus Ligustri Lucidi, 100 parts of Radix Rhodiolae, 120 parts of Fructus Lycii, 200 parts of Radix Pseudostellariae, 200 parts of the Fructus Sophorae, 100 parts of Cortex Pseudolaricis, the Radix Stemonae
200 parts, 150 parts of the Radix Angelicae Dahuricae, 150 parts of Periostracum Cicadae, 150 parts of Radix Saposhnikoviae, 150 parts of Herba Schizonepetae, 150 parts of Radix Scutellariae, 0.0015 part of aspartame, benzene first
0.0015 part of sour sodium；
Its preparation process is:
(1) take raw material Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Ganoderma, Fructus Rubi, Fructus Rosae Laevigatae to put into pulverizer to pulverize, cross 100 mesh sieves, obtain
Raw material powder, standby；
(2) take raw material Semen Euryaless, Fructus Mori, Fructus Ligustri Lucidi, Radix Rhodiolae, Fructus Lycii, Radix Pseudostellariae to put into pulverizer to pulverize, cross 60 mesh sieves,
Obtain raw material powder, standby；
(3) take the raw material Fructus Sophorae, Cortex Pseudolaricis, the Radix Stemonae, the Radix Angelicae Dahuricae, Periostracum Cicadae, Radix Saposhnikoviae, Herba Schizonepetae, Radix Scutellariae to put into pulverizer to pulverize, cross 80 mesh
Sieve, obtains raw material powder, standby；
(4) step (1) gained raw material powder and step (2) gained raw material powder and (3) gained raw material powder are added water to cook twice, first
The secondary water adding raw material weight 10 times amount, decocts 0.8 hour, pours out medicinal liquid, and the water that second adds raw material weight 8 times amount decocts 0.8
Hour, merge medicinal liquid twice, filter, filtrate is concentrated into 55 DEG C and surveys the clear paste that relative density is 1.08, the appropriate amount of ethanol plus 95%, 8
DEG C standing 24 when, filter, decompression filtrate recycling ethanol to no alcohol taste, filtrate be concentrated into 60 DEG C survey relative density be 1.25 thick
Cream, standby；
(5) raw material aspartame, sodium benzoate is taken to be dissolved into respectively in water, standby；
(6) step (4) gained thick paste is added the pure water of its weight 3-5 times amount, add in step (3) Cornu Cervi is peptized
Liquid, adds step (5) gained aspartame, sodium benzoate, and 5min is to being completely dissolved, with centrifugal filtration, revolution for stirring
10000r/min, the time be 5s, cold preservation, standing 24 when, then use centrifugal filtration, revolution 16000r/min, the time be 5s, finally seal
It is loaded on sealing in 20ml bottle, with the sterilizing in 15 minutes of boiling water high temperature, cooling, packaging, obtain final product the Chinese medicine preparation for the treatment of hemorrhoid.
Used by the present invention, the pharmacology of raw material of Chinese medicine medicine is as follows:
Radix Rehmanniae: meridian distribution of property and flavor: sweet, bitter, tremble with fear, GUIXIN, liver and kidney channel；Effect: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting；Cure mainly: for heat
Sick vexed, crimson tongue, blood-head tells nosebleed, atropurpureus macula, consumption of YIN caused by febrile disease, polydipsia of quenching one's thirst.Radix Salviae Miltiorrhizae: meridian distribution of property and flavor: bitter, it is slightly cold, GUIXIN, liver
Warp；Indication: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness that clears away heart-fire；For menoxenia, closed dysmenorrhea, note of the ancient Chinese abdominal mass is gathered, and chest and abdomen pierce
Bitterly, hot numbness pain, sore swell and ache curative, dysphoria and insomnia；Hepatosplenomegaly, angina pectoriss.
Rhizoma Alismatis: meridian distribution of property and flavor: sweet, tremble with fear, return kidney, bladder warp；Indication: diuresis, clearing away damp-heat；For dysuria,
Oedema turgor, oliguria of having loose bowels, dizziness due to fluid-retention, puckery pain of heat gonorrhea；Hyperlipidemia.
Ganoderma: meridian distribution of property and flavor: sweet, put down, GUIXIN, lung, liver and kidney channel；Cure mainly asthenia, cough, asthma, insomnia, dyspepsia,
Malignant tumor etc..
Fructus Rubi: meridian distribution of property and flavor: sweet, sour, temperature, return kidney, bladder warp；Indication: kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination；For kidney deficiency
The enuresis, frequent micturition, impotence and premature ejaculation, emission and spermatorrhea.
Fructus Rosae Laevigatae: meridian distribution of property and flavor: sour, sweet, puckery, put down, return kidney, bladder, large intestine channel；Indication: astringent sperm contracting urine, astringing intestine to stop diarrhea stops
Rush down；For emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, protracted dysentery and diarrhea.
Semen Euryaless: meridian distribution of property and flavor: sweet, puckery, put down, returns spleen, kidney channel；Indication: supplementing the kidney to control the nocturnal, tonifying spleen and stopping diarrhea, tonifying spleen and stopping diarrhea；
For emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.
Fructus Mori: nature and flavor: sweet in the mouth, cold in nature, return through: enter the heart, liver and kidney channel；Function: nourishing YIN and supplementing blood, improving eyesight is promoted the production of body fluid, intestine moistening；
Cure mainly: weakness due to chronic disease, hepatic and renal YIN deficiency, soreness of the waist and knees, the dark tinnitus of mesh, articular instability, dry constipation of intestines, body fluid deficiency insufficiency of blood, hectic fever is passed out semen,
Diabetes etc..
Fructus Ligustri Lucidi: meridian distribution of property and flavor: sweet, bitter, cold, return liver and kidney channel；Indication: nourishing the liver and kidney, improving eyesight black hair；For dizzy
Dizzy tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.
Radix Rhodiolae: nature and flavor: cold, sweet, puckery, return lung warp, there is tonifying Qi clearing lung-heat, Fructus Alpiniae Oxyphyllae nourishing heart, hemostasis with astringents, dissipating blood stasis for subsidence of swelling
Effect；Main deficiency of vital energy and physically weak, fear of cold after being ill, shortness of breath and fatigue, cough due to lung-heat, spitting of blood, leucorrhea is suffered from diarrhoea, traumatic injury, burn and scald, nerve
Disease, altitude sickness.
Fructus Lycii: meridian distribution of property and flavor: sweet, put down, return liver and kidney channel；Indication: nourishing the liver and kidney, replenishing vital essence to improve eyesight；For asthenia essence
Lose, soreness of waist and knee joint, vertigo and tinnitus, Heat Diabetes, blood deficiency and yellow complexion, blurred vision.
Radix Pseudostellariae: meridian distribution of property and flavor: sweet, slight bitter, put down, returns spleen, lung meridian；Indication: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung；For
Insufficiency of the spleen body is tired, inappetence, eak after being ill, deficiency of both vital energy and Yin, and spontaneous perspiration is thirsty, dryness of the lung dry cough.
The Fructus Sophorae: meridian distribution of property and flavor: bitter, tremble with fear, Return liver, large intestine channel；Indication: clearing away heat-fire, cooling blood for hemostasis；For intestinal heat just
Blood, hemorrhoid swell bleeding, and liver-heat is had a headache, dizziness conjunctival congestion.
Cortex Pseudolaricis: meridian distribution of property and flavor: pungent, temperature；Poisonous, return lung, spleen channel；Indication: parasite killing, antipruritic；For scabies prurituss.
The Radix Stemonae: meridian distribution of property and flavor: sweet, bitter, tepor, return lung warp；Indication: nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing；For new chronic cough
Cough, pulmonary tuberculosis cough, pertussis；It is used for outward head louse, body louse, enterobiasiss, pudendal pruritus；Sweet Radix Stemonae nourishing the lung to arrest cough；For deficiency of YIN chronic cough.
The Radix Angelicae Dahuricae: meridian distribution of property and flavor: pungent, temperature, return stomach, large intestine, lung meridian；Indication: scattered wind dehumidifying, sensible pain relieving, detumescence row
Pus；For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, sore swell and ache curative.
Periostracum Cicadae: meridian distribution of property and flavor: sweet, tremble with fear, return lung, Liver Channel；Indication: scattered wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic；
For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella itch, cataract, convulsion with spasms, tetanus.
Radix Saposhnikoviae: meridian distribution of property and flavor: acrid, sweet, warm, return bladder, liver, spleen channel；Indication: inducing diaphoresis to dispel wind, wins wet, relieving convulsion；With
In headache due to common cold, rheumatic arthralgia, rubella itch, tetanus.
Herba Schizonepetae: meridian distribution of property and flavor: pungent, tepor, return lung, Liver Channel；Indication: induce sweat scattered wind, rash；For catching a cold, headache,
Measles, rubella, skin infection from the beginning of；Parch to black treating hematochezia, metrorrhagia, puerperal blood faintss.
Radix Scutellariae: meridian distribution of property and flavor: bitter, tremble with fear, return lung, gallbladder, spleen, large intestine, small intestine meridian；Indication: heat clearing and damp drying, pathogenic fire purging solution
Poison, hemostasis, antiabortive；For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, hyperpyrexia excessive thirst, heat in blood
Tell nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
The invention has the advantages that: having functions that clearing away heat to stop bleeding, nourishing yin and purging fire, drug effect is notable, can long-term taking, Huan Zheyi
In acceptance.
Specific embodiment
Describe technical scheme with reference to embodiment and experimental example in detail, but protection domain not limited to this.
Embodiment 1
A kind of Chinese medicine preparation treating hemorrhoid, is made up of the raw material of following weight portion: 180 parts of Radix Rehmanniae, 180 parts of Radix Salviae Miltiorrhizae, Rhizoma Alismatis
180 parts, 180 parts of Ganoderma, 180 parts of Fructus Rubi, 180 parts of Fructus Rosae Laevigatae, 180 parts of Semen Euryaless, 180 parts of Fructus Mori, 180 parts of Fructus Ligustri Lucidi, red
130 parts of Herba hylotelephii erythrosticti, 150 parts of Fructus Lycii, 230 parts of Radix Pseudostellariae, 230 parts of the Fructus Sophorae, 130 parts of Cortex Pseudolaricis, 230 parts of the Radix Stemonae, 180 parts of the Radix Angelicae Dahuricae,
180 parts of Periostracum Cicadae, 180 parts of Radix Saposhnikoviae, 180 parts of Herba Schizonepetae, 180 parts of Radix Scutellariae, 0.002 part of aspartame, 0.002 part of sodium benzoate；
Its preparation process is:
(1) take raw material Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Ganoderma, Fructus Rubi, Fructus Rosae Laevigatae to put into pulverizer to pulverize, cross 80-100 mesh sieve,
Obtain raw material powder, standby；
(2) take raw material Semen Euryaless, Fructus Mori, Fructus Ligustri Lucidi, Radix Rhodiolae, Fructus Lycii, Radix Pseudostellariae to put into pulverizer to pulverize, cross 50-60 mesh
Sieve, obtains raw material powder, standby；
(3) take the raw material Fructus Sophorae, Cortex Pseudolaricis, the Radix Stemonae, the Radix Angelicae Dahuricae, Periostracum Cicadae, Radix Saposhnikoviae, Herba Schizonepetae, Radix Scutellariae to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
(4) step (1) gained raw material powder and step (2) gained raw material powder and (3) gained raw material powder are added water to cook twice, first
The secondary water adding raw material weight 10-12 times amount, decocts 0.4-1 hour, pours out medicinal liquid, the water that second adds raw material weight 6-8 times amount,
Decoct 0.4-1 hour, merge medicinal liquid twice, filter, filtrate is concentrated into 55-60 DEG C and surveys the clear paste that relative density is 1.08-1.15,
Plus the appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filter, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
(5) raw material aspartame, sodium benzoate is taken to be dissolved into respectively in water, standby；
(6) step (4) gained thick paste is added the pure water of its weight 3-5 times amount, add the aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, cold preservation,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of hemorrhoid.
Usage: oral, 2 times a day, each 15ml.
Embodiment 2
A kind of Chinese medicine preparation treating hemorrhoid, is made up of the raw material of following weight portion: 150 parts of Radix Rehmanniae, 150 parts of Radix Salviae Miltiorrhizae, Rhizoma Alismatis
150 parts, 150 parts of Ganoderma, 150 parts of Fructus Rubi, 150 parts of Fructus Rosae Laevigatae, 150 parts of Semen Euryaless, 150 parts of Fructus Mori, 150 parts of Fructus Ligustri Lucidi, red
100 parts of Herba hylotelephii erythrosticti, 120 parts of Fructus Lycii, 200 parts of Radix Pseudostellariae, 200 parts of the Fructus Sophorae, 100 parts of Cortex Pseudolaricis, 200 parts of the Radix Stemonae, 150 parts of the Radix Angelicae Dahuricae,
150 parts of Periostracum Cicadae, 150 parts of Radix Saposhnikoviae, 150 parts of Herba Schizonepetae, 150 parts of Radix Scutellariae, 0.0015 part of aspartame, 0.0015 part of sodium benzoate；
Its preparation process is:
(1) take raw material Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Ganoderma, Fructus Rubi, Fructus Rosae Laevigatae to put into pulverizer to pulverize, cross 80-100 mesh sieve,
Obtain raw material powder, standby；
(2) take raw material Semen Euryaless, Fructus Mori, Fructus Ligustri Lucidi, Radix Rhodiolae, Fructus Lycii, Radix Pseudostellariae to put into pulverizer to pulverize, cross 50-60 mesh
Sieve, obtains raw material powder, standby；
(3) take the raw material Fructus Sophorae, Cortex Pseudolaricis, the Radix Stemonae, the Radix Angelicae Dahuricae, Periostracum Cicadae, Radix Saposhnikoviae, Herba Schizonepetae, Radix Scutellariae to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
(4) step (1) gained raw material powder and step (2) gained raw material powder and (3) gained raw material powder are added water to cook twice, first
The secondary water adding raw material weight 10-12 times amount, decocts 0.4-1 hour, pours out medicinal liquid, the water that second adds raw material weight 6-8 times amount,
Decoct 0.4-1 hour, merge medicinal liquid twice, filter, filtrate is concentrated into 55-60 DEG C and surveys the clear paste that relative density is 1.08-1.15,
Plus the appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filter, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
(5) raw material aspartame, sodium benzoate is taken to be dissolved into respectively in water, standby；
(6) step (4) gained thick paste is added the pure water of its weight 3-5 times amount, add the aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, cold preservation,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of hemorrhoid.
Usage: oral, 2 times a day, each 15ml.
Embodiment 3
A kind of Chinese medicine preparation treating hemorrhoid, is made up of the raw material of following weight portion: 120 parts of Radix Rehmanniae, 120 parts of Radix Salviae Miltiorrhizae, Rhizoma Alismatis
120 parts, 120 parts of Ganoderma, 120 parts of Fructus Rubi, 120 parts of Fructus Rosae Laevigatae, 120 parts of Semen Euryaless, 120 parts of Fructus Mori, 120 parts of Fructus Ligustri Lucidi, red
70 parts of Herba hylotelephii erythrosticti, 90 parts of Fructus Lycii, 170 parts of Radix Pseudostellariae, 170 parts of the Fructus Sophorae, 70 parts of Cortex Pseudolaricis, 170 parts of the Radix Stemonae, 120 parts of the Radix Angelicae Dahuricae, Periostracum Cicadae
120 parts, 120 parts of Radix Saposhnikoviae, 120 parts of Herba Schizonepetae, 120 parts of Radix Scutellariae, 0.001 part of aspartame, 0.001 part of sodium benzoate；
Its preparation process is:
(1) take raw material Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Ganoderma, Fructus Rubi, Fructus Rosae Laevigatae to put into pulverizer to pulverize, cross 80-100 mesh sieve,
Obtain raw material powder, standby；
(2) take raw material Semen Euryaless, Fructus Mori, Fructus Ligustri Lucidi, Radix Rhodiolae, Fructus Lycii, Radix Pseudostellariae to put into pulverizer to pulverize, cross 50-60 mesh
Sieve, obtains raw material powder, standby；
(3) take the raw material Fructus Sophorae, Cortex Pseudolaricis, the Radix Stemonae, the Radix Angelicae Dahuricae, Periostracum Cicadae, Radix Saposhnikoviae, Herba Schizonepetae, Radix Scutellariae to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
(4) step (1) gained raw material powder and step (2) gained raw material powder and (3) gained raw material powder are added water to cook twice, first
The secondary water adding raw material weight 10-12 times amount, decocts 0.4-1 hour, pours out medicinal liquid, the water that second adds raw material weight 6-8 times amount,
Decoct 0.4-1 hour, merge medicinal liquid twice, filter, filtrate is concentrated into 55-60 DEG C and surveys the clear paste that relative density is 1.08-1.15,
Plus the appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filter, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
(5) raw material aspartame, sodium benzoate is taken to be dissolved into respectively in water, standby；
(6) step (4) gained thick paste is added the pure water of its weight 3-5 times amount, add the aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, cold preservation,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of hemorrhoid.
Usage: oral, 2 times a day, each 15ml.
Chinese medicine preparation Ureteral Calculus hemorrhoid patients of the present invention 40, clinical report is as follows:
1st, physical data
Clinical observation hemorrhoid patients 40, wherein man 19, female 21, minimum 19 years old, maximum 75 years old, 47 years old mean age, disease
Journey 7 days -10 years.
2nd, diagnostic criteria
1. have blood in stool and the swollen thing of podex, can have rectal tenesmus, foreign body sensation or pain；
2. can be with merocrine secretion's thing or prurituss；
3. the tooth trace swollen thing of same orientation appearance up and down in anal canal.
3rd, Therapeutic Method
Using Chinese medicine preparation of the present invention treatment, oral Chinese medicine preparation of the present invention, 2 times a day, each 15ml, is within 7 days a course for the treatment of.
4th, efficacy evaluation
Cure: symptom disappears, hemorrhoid disappear；
Take a turn for the better: symptom is improved, hemorrhoid reduce；
Invalid: symptom, sign are all unchanged.
5th, therapeutic outcome
In clinical treatment hemorrhoid patients 40, cure 33 and account for 82.5%, taking a turn for the better 7 accounts for 17.5%, invalid 0, total effective rate is
100%.
6th, model case
Case 1: female, 49 years old, patient main suit stool had thing abjection, bleeding, hemorrhoid 10 years, had thing to project after an action of the bowels it is impossible to voluntarily go back
Receive, voluntarily give ZHICHUANG GAO external curing effect on driving birds is not good, symptom can not be alleviated, to examine, oral one treatment of Chinese medicine preparation of the present invention
Journey, patient symptom substantially mitigates, and two courses for the treatment of of oral traditional Chinese medicine preparation, and symptom is clearly better, and of the present invention Chinese medicine preparation is administered orally again
Two courses for the treatment of, clinical cure.
Case 2: female, 25 years old, is hard and dry, intermittence is had blood in stool, over nearly 25 days, has blood in stool in spurting, color is scarlet, this is administered orally
One course for the treatment of of invention Chinese medicine preparation, patient symptom substantially mitigates, and just adjusts blood to stop, and one course for the treatment of of oral traditional Chinese medicine preparation, and symptom is bright
Aobvious improvement, is administered orally one course for the treatment of of Chinese medicine preparation of the present invention, clinical cure again.
Case 3: man, 33 years old, it is hard and dry over nearly 17 days, the swollen thing pain of anus burst 2 days, because being hard and dry, squat long and exert
Cause after duty defecation；Now feel that the swollen thing of anus edge can not also be received, matter is hard and unbearably painful, oral one treatment of Chinese medicine preparation of the present invention
Journey, symptom is clearly better, and of the present invention Chinese medicine preparation one course for the treatment of, clinical cure are administered orally again.
It should be pointed out that the specific embodiment more representational example that is the present invention is it is clear that the skill of the present invention
Art scheme is not limited to above-described embodiment, can also have many variations；Those of ordinary skill in the art, clearly public with present invention institute
What what written description that open or according to file was undoubted obtained, all it is considered as this patent scope of the claimed.
Claims (6)
1. a kind of Chinese medicine preparation treating hemorrhoid and preparation method it is characterised in that: be made up of the raw material of following weight portion: the Radix Rehmanniae
Yellow 120-180 part, Radix Salviae Miltiorrhizae 120-180 part, Rhizoma Alismatis 120-180 part, Ganoderma 120-180 part, Fructus Rubi 120-180 part, Fructus Rosae Laevigatae
120-180 part, Semen Euryaless 120-180 part, Fructus Mori 120-180 part, Fructus Ligustri Lucidi 120-180 part, Radix Rhodiolae 70-130 part, Fructus Lycii
90-150 part, Radix Pseudostellariae 170-230 part, Fructus Sophorae 170-230 part, Cortex Pseudolaricis 70-130 part, Radix Stemonae 170-230 part, Radix Angelicae Dahuricae 120-
180 parts, Periostracum Cicadae 120-180 part, Radix Saposhnikoviae 120-180 part, Herba Schizonepetae 120-180 part, Radix Scutellariae 120-180 part, aspartame 0.001-
0.002 part, sodium benzoate 0.001-0.002 part.
2. a kind of Chinese medicine preparation treating hemorrhoid according to claim 1 preparation method it is characterised in that: its preparation step
Suddenly it is:
(1) take raw material Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Ganoderma, Fructus Rubi, Fructus Rosae Laevigatae to put into pulverizer to pulverize, cross 80-100 mesh sieve,
Obtain raw material powder, standby；
(2) take raw material Semen Euryaless, Fructus Mori, Fructus Ligustri Lucidi, Radix Rhodiolae, Fructus Lycii, Radix Pseudostellariae to put into pulverizer to pulverize, cross 50-60 mesh
Sieve, obtains raw material powder, standby；
(3) take the raw material Fructus Sophorae, Cortex Pseudolaricis, the Radix Stemonae, the Radix Angelicae Dahuricae, Periostracum Cicadae, Radix Saposhnikoviae, Herba Schizonepetae, Radix Scutellariae to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
(4) step (1) gained raw material powder and step (2) gained raw material powder and (3) gained raw material powder are added water to cook twice, first
The secondary water adding raw material weight 10-12 times amount, decocts 0.4-1 hour, pours out medicinal liquid, the water that second adds raw material weight 6-8 times amount,
Decoct 0.4-1 hour, merge medicinal liquid twice, filter, filtrate is concentrated into 55-60 DEG C and surveys the clear paste that relative density is 1.08-1.15,
Plus the appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filter, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
(5) raw material aspartame, sodium benzoate is taken to be dissolved into respectively in water, standby；
(6) step (4) gained thick paste is added the pure water of its weight 3-5 times amount, add the aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, cold preservation,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of hemorrhoid.
3. a kind of Chinese medicine preparation treating hemorrhoid according to claim 2 preparation method it is characterised in that:
Its preparation process is:
(1) take raw material Radix Rehmanniae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis, Ganoderma, Fructus Rubi, Fructus Rosae Laevigatae to put into pulverizer to pulverize, cross 100 mesh sieves, obtain
Raw material powder, standby；
(2) take raw material Semen Euryaless, Fructus Mori, Fructus Ligustri Lucidi, Radix Rhodiolae, Fructus Lycii, Radix Pseudostellariae to put into pulverizer to pulverize, cross 60 mesh sieves,
Obtain raw material powder, standby；
(3) take the raw material Fructus Sophorae, Cortex Pseudolaricis, the Radix Stemonae, the Radix Angelicae Dahuricae, Periostracum Cicadae, Radix Saposhnikoviae, Herba Schizonepetae, Radix Scutellariae to put into pulverizer to pulverize, cross 80 mesh
Sieve, obtains raw material powder, standby；
(4) step (1) gained raw material powder and step (2) gained raw material powder and (3) gained raw material powder are added water to cook twice, first
The secondary water adding raw material weight 10 times amount, decocts 0.8 hour, pours out medicinal liquid, and the water that second adds raw material weight 8 times amount decocts 0.8
Hour, merge medicinal liquid twice, filter, filtrate is concentrated into 55 DEG C and surveys the clear paste that relative density is 1.08, the appropriate amount of ethanol plus 95%, 8
DEG C standing 24 when, filter, decompression filtrate recycling ethanol to no alcohol taste, filtrate be concentrated into 60 DEG C survey relative density be 1.25 thick
Cream, standby；
(5) raw material aspartame, sodium benzoate is taken to be dissolved into respectively in water, standby；
(6) step (4) gained thick paste is added the pure water of its weight 3-5 times amount, add in step (3) Cornu Cervi is peptized
Liquid, adds step (5) gained aspartame, sodium benzoate, and 5min is to being completely dissolved, with centrifugal filtration, revolution for stirring
10000r/min, the time be 5s, cold preservation, standing 24 when, then use centrifugal filtration, revolution 16000r/min, the time be 5s, finally seal
It is loaded on sealing in 20ml bottle, with the sterilizing in 15 minutes of boiling water high temperature, cooling, packaging, obtain final product the Chinese medicine preparation for the treatment of hemorrhoid.
4. a kind of Chinese medicine preparation treating hemorrhoid according to claim 1 it is characterised in that: by the raw material of following weight portion
Make: 150 parts of Radix Rehmanniae, 150 parts of Radix Salviae Miltiorrhizae, 150 parts of Rhizoma Alismatis, 150 parts of Ganoderma, 150 parts of Fructus Rubi, 150 parts of Fructus Rosae Laevigatae, Semen Euryaless
150 parts, 150 parts of Fructus Mori, 150 parts of Fructus Ligustri Lucidi, 100 parts of Radix Rhodiolae, 120 parts of Fructus Lycii, 200 parts of Radix Pseudostellariae, 200 parts of the Fructus Sophorae,
100 parts of Cortex Pseudolaricis, 200 parts of the Radix Stemonae, 150 parts of the Radix Angelicae Dahuricae, 150 parts of Periostracum Cicadae, 150 parts of Radix Saposhnikoviae, 150 parts of Herba Schizonepetae, 150 parts of Radix Scutellariae, A Si
0.0015 part of Ba Tian, 0.0015 part of sodium benzoate.
5. a kind of Chinese medicine preparation treating hemorrhoid according to claim 1 it is characterised in that: by the raw material of following weight portion
Make: 180 parts of Radix Rehmanniae, 180 parts of Radix Salviae Miltiorrhizae, 180 parts of Rhizoma Alismatis, 180 parts of Ganoderma, 180 parts of Fructus Rubi, 180 parts of Fructus Rosae Laevigatae, Semen Euryaless
180 parts, 180 parts of Fructus Mori, 180 parts of Fructus Ligustri Lucidi, 130 parts of Radix Rhodiolae, 150 parts of Fructus Lycii, 230 parts of Radix Pseudostellariae, 230 parts of the Fructus Sophorae,
130 parts of Cortex Pseudolaricis, 230 parts of the Radix Stemonae, 180 parts of the Radix Angelicae Dahuricae, 180 parts of Periostracum Cicadae, 180 parts of Radix Saposhnikoviae, 180 parts of Herba Schizonepetae, 180 parts of Radix Scutellariae, A Si
0.002 part of Ba Tian, 0.002 part of sodium benzoate.
6. a kind of Chinese medicine preparation treating hemorrhoid according to claim 1 it is characterised in that: by the raw material of following weight portion
Make: 120 parts of Radix Rehmanniae, 120 parts of Radix Salviae Miltiorrhizae, 120 parts of Rhizoma Alismatis, 120 parts of Ganoderma, 120 parts of Fructus Rubi, 120 parts of Fructus Rosae Laevigatae, Semen Euryaless
120 parts, 120 parts of Fructus Mori, 120 parts of Fructus Ligustri Lucidi, 70 parts of Radix Rhodiolae, 90 parts of Fructus Lycii, 170 parts of Radix Pseudostellariae, 170 parts of the Fructus Sophorae, soil
70 parts of rose of Sharon skin, 170 parts of the Radix Stemonae, 120 parts of the Radix Angelicae Dahuricae, 120 parts of Periostracum Cicadae, 120 parts of Radix Saposhnikoviae, 120 parts of Herba Schizonepetae, 120 parts of Radix Scutellariae, aspartame
0.001 part, 0.001 part of sodium benzoate.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1451419A (en) * | 2002-04-19 | 2003-10-29 | 殷继兴 | Chinese medicine composition for treating pile |
| CN101897788A (en) * | 2009-05-27 | 2010-12-01 | 贠钦亮 | Traditional Chinese medicinal pulvis for treating haemorrhoids and fistula |
| CN102370790A (en) * | 2010-08-19 | 2012-03-14 | 贠钦亮 | Chinese herbal powder for treating hemorrhoids and fistula |
-
2016
- 2016-11-11 CN CN201610992024.9A patent/CN106362059A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1451419A (en) * | 2002-04-19 | 2003-10-29 | 殷继兴 | Chinese medicine composition for treating pile |
| CN101897788A (en) * | 2009-05-27 | 2010-12-01 | 贠钦亮 | Traditional Chinese medicinal pulvis for treating haemorrhoids and fistula |
| CN102370790A (en) * | 2010-08-19 | 2012-03-14 | 贠钦亮 | Chinese herbal powder for treating hemorrhoids and fistula |
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Application publication date: 20170201 |