CN106361254B - A kind of separate type capsule - Google Patents

A kind of separate type capsule Download PDF

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Publication number
CN106361254B
CN106361254B CN201610854105.2A CN201610854105A CN106361254B CN 106361254 B CN106361254 B CN 106361254B CN 201610854105 A CN201610854105 A CN 201610854105A CN 106361254 B CN106361254 B CN 106361254B
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cabin
baffle plate
signal
secondary cabin
main cabin
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CN106361254A (en
Inventor
乔盼盼
刘洪英
皮喜田
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Chongqing University
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Chongqing University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041Capsule endoscopes for imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661Endoscope light sources
    • A61B1/0684Endoscope light sources using light emitting diodes [LED]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4261Evaluating exocrine secretion production
    • A61B5/4283Evaluating exocrine secretion production gastrointestinal secretions, e.g. bile production

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Physiology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides a kind of detachable capsule, detect the disease marker in gastric juice, and the true picture of stomach is obtained simultaneously, the detachable capsule of the present invention includes main cabin, secondary cabin one and secondary cabin two, and main cabin includes wireless transmitter module, minicell, energy supply control module, signal acquisition control circuit;Image acquisition circuit or gastric juice detection sensor are included in secondary cabin one, includes image acquisition circuit or gastric juice detection sensor in secondary cabin two, described image Acquisition Circuit includes LED light group, cmos sensor and microcontroller;It is connected between secondary cabin one and secondary cabin two and main cabin by degradable retainer ring, after degradable retainer ring degraded, secondary cabin one and secondary cabin two come off from main cabin.Detachable capsule provided by the present invention, the picture of gastrointestinal wall can be not only shot, a variety of disease markers can also be detected simultaneously;After detection is completed, two secondary cabins of capsule separate with main cabin, capsule cumulative volume is diminished, and effectively reduce capsule and enter the risk that human body can not discharge.

Description

A kind of separate type capsule
Technical field
The present invention relates to medicinal detection device, specifically a kind of detachable capsule, by capsule of eating, intestines and stomach are detected Disease.
Background technology
On clinical medicine, the diagnosis of stomach trouble is mostly since the detection of gastric juice, at present, extract the major way of gastric juice by In gastroscope, light microscope being inserted in stomach from oral cavity and carries out taking liquid to operate, patient suffering is big, although being used cooperatively arcotic, But still pain is unbearably, and gastroscope can only also extract gastric juice, and other checked operations are to carry out in vitro.
A kind of gastric juice detector is proposed in patent CN02268048, Test paper is bundled into test paper group with lead, is tried Spitball is wrapped in soluble big envelope, and the end of lead is placed in outside soluble big envelope.Although patient is easy to use, on the one hand cure Raw workload is big, when another aspect person under inspection takes test paper group, when staying in the fine rule of outside and pulling out capsule, can produce evil The discomfort such as the heart, vomiting, and unhygienic convenience.
A kind of Novel intellectual detection system of gastric fluid occult blood is proposed in patent CN201210134190, the gastric juice is occulted blood capsule Main to be occulted blood detection module, imaging sensor, microprocessor, signal wireless transmitter module etc. including gastric juice, gastric juice is occulted blood detection Module detection gastric juice, which is occulted blood, situation and is presented color change, imaging sensor acquisition testing result images information, through microprocessor Launched after processing by signal wireless transmitter module to external.Using the capsule of occulting blood, subject carry out gastric juice occult blood examination when without Create, be painless.But due to detecting the limitation of end spaces, the detection mark of the capsule system only only has stomach to occult blood one kind, it is impossible to Multiple markers are detected simultaneously, and have a certain distance to be used for focusing between imaging sensor and Test paper, occupy capsule Interior much room.
The content of the invention
For overcome the deficiencies in the prior art, the invention provides a kind of detachable capsule, detects the disease among gastric juice Sick mark, and the true picture of stomach is obtained simultaneously, accuracy simple to operate, easy to use, disease detection is high;Capsule cabin After body separation, overall volume diminishes, and is easy to excrete, and substantially reduces the risk of capsule detection.
Technical scheme:
Detachable capsule, including main cabin, secondary cabin one and secondary cabin two, main cabin include wireless transmitter module, minicell, electricity Source control module, signal acquisition control circuit;Image acquisition circuit or gastric juice detection sensor are included in secondary cabin one, in secondary cabin two Comprising image acquisition circuit or gastric juice detection sensor, described image Acquisition Circuit includes LED light group, cmos sensor and micro-control Device processed;It is connected between secondary cabin one and secondary cabin two and main cabin by degradable retainer ring, it is secondary after degradable retainer ring degraded Separation comes off from main cabin for cabin one and secondary cabin two.
There are two transparent watertight baffle plates to be individually fixed in secondary cabin one and main cabin between main cabin and secondary cabin one;Main cabin and secondary cabin There are two transparent watertight baffle plates to be individually fixed in main cabin and secondary cabin two between two.
The shell of nacelle is transparent where described image Acquisition Circuit;Nacelle where gastric juice detection sensor has logical Hole, gastric juice is set to enter;Minicell uses three pieces of button cells;The lampet number of LED light group 14 is 2~4, using patch Flat type LED, color use white light.
The degradable retainer ring is annularly surrounded on outside capsule in main cabin and secondary cabin one, the joint in main cabin and secondary cabin two The outside of shell, width are 2~5mm, and material is degradation material, the one kind being chosen in particular from following material:Shellac, polyvinyl alcohol It is acetate phthalate ester, acrylic resin, cellulose acetate phthalate, Hydroxypropyl Methylcellulose Phathalate, poly- Lactic acid.
Energy and signal are transmitted by wire or contact between described image Acquisition Circuit and main cabin.
Wired or wireless connection is used between the gastric juice detection sensor and signal acquisition control circuit, wherein wired company It is connected in wire connection or contact portion;During wireless connection, the signal that signal acquisition control circuit is gathered is optical signal or image Information or electromagnetic information.
Wire connection, conductor material is aluminium, can be decomposed by hydrochloric acid in gastric juice, and length is 5~20mm, a diameter of 0.5~ 1.5mm, wire penetrates two baffle plates, and scribbles marine glue on the surface for penetrating baffle plate;The contact also through two baffle plates, and And the surface smear marine glue at place is penetrated by contact in two baffle plates.
Contact includes upper connecting rod, upper end tactile disk, lower end tactile disk, lower pull bar, pin hole and contact pilotage;The thickness of upper end tactile disk is 0.5~2mm, the contact area with lower end tactile disk are 2~12mm2, it is shaped as circular or ellipse or rectangle or rhombus or trapezoidal; The thickness and shape of lower end tactile disk are identical with upper end tactile disk;Pin hole is cylindrical hole, a diameter of 1~2mm, highly less than upper end tactile disk Thickness, number be 1~3;The contact pilotage is cylinder, and diameter is slightly less than pin hole, highly identical with pin hole or slightly above pin Hole, number and position distribution are identical with pin hole.
Gastric juice detection sensor is that Test paper or reagent or electrode or more are combined;Test paper is selected from following It is one or more of:Hemoglobin Test paper, transferrins Test paper, detecting paper for pylorus spiral bacillus and carcinomebryonic antigen Test paper;Detecting electrode is selected from following one or more:PH detecting electrodes, hemoglobin detecting electrode and temperature detection Electrode.
The signal that signal acquisition control circuit is gathered is the one or more of signals below form:Picture signal, numeral Encoded signal, optical signal, current signal, voltage signal, pressure signal, electromagnetic signal.
The course of work of the present invention:
The detachable capsule enters in stomach by oral administration, and gastric juice enters secondary cabin, gastric juice detection sensor and stomach by through hole Liquid contacts, and detects the information of disease of stomach mark, and signal acquisition control circuit gathers and handles the detection of gastric juice detection sensor The information arrived, then it is transferred in vitro by wireless transmitter module;Meanwhile the image inside image acquisition circuit shooting stomach, figure As information by wire or contact sends wireless transmitter module to, it is transferred in vitro by wireless transmitter module.Capsule enters small intestine Afterwards, degradable retainer ring starts gradually to degrade, and secondary cabin one and secondary cabin two separate with main cabin, three independent nacelles is formed, in glue During capsule separates, image acquisition circuit can still gather the picture in a part of small intestine, there is provided the inspection information of small intestine, directly It is fully disconnected to contact, stops shooting
Detachable capsule provided by the present invention, after detection is completed, two secondary cabins of capsule separate with main cabin, make glue Capsule cumulative volume diminishes, and effectively reduces capsule and enters the risk that human body can not discharge;Detachable capsule provided by the present invention is not The picture of gastrointestinal wall can be only shot, can also non-invasively detect the disease marker in gastric juice, and a variety of marks can be detected simultaneously Will thing, accuracy simple to operate, easy to use, disease detection are high.
Brief description of the drawings:
Fig. 1 is the structural representation of separate type capsule of the present invention;
Fig. 2 is the separate type capsule structure schematic diagram of the embodiment of the present invention one;
Fig. 3 is the separate type capsule structure schematic diagram of the embodiment of the present invention two;
Fig. 4 is contact structure schematic diagram;
Fig. 5 is the sun of hemoglobin Test paper and carcinomebryonic antigen Test paper in the embodiment of the present invention one and embodiment two Property result schematic diagram.
Fig. 1 is into Fig. 5:
The main cabins of 1 ━, 2 ━ pairs cabins one, 3 ━ pairs cabins two, 4 ━ wireless transmitter modules, 5 ━ minicells, 6 ━ power supply moulds Block, 7 ━ baffle plates, 7a ━ baffle plates, 7b ━ baffle plates, 7c ━ baffle plates, 7d ━ baffle plates, 8 ━ signal acquisitions control circuits, the inspection of 9 ━ gastric juice Sensor, 10 ━ microcontrollers, 10a ━ microcontrollers, 11 ━ through holes, 12 ━ hemoglobins Test papers, 13 ━ cancer embryos are surveyed to resist Former Test paper, 14 ━ LED light groups, 14a ━ LED light groups, 15 ━ cmos sensors, 15a ━ cmos sensors, 16 ━ are degradable Retainer ring, 17 ━ absorbent wools, 18 ━ pH detection probes, 19 ━ pH detection sensors, 20 ━ signal acquisitions control circuits, 21 ━ are led Pull bar, 25 ━ upper ends tactile disks, 26 ━ lower ends tactile disks, 27 ━ pin holes, 28 ━ are touched under line, 22 ━ contacts, 23 ━ upper connecting rods, 24 ━ Pin, 29 ━ image acquisition circuits.
Embodiment
Embodiment one
As shown in Fig. 2 a kind of detachable capsule, including main cabin 1, secondary cabin 1 and secondary cabin 23, main cabin 1 include wireless hair Module 4, minicell 5, energy supply control module 6, signal acquisition control circuit 8 are penetrated, signal acquisition control circuit 8 includes LED Group 14a, cmos sensor 15a, microcontroller 10a;It is image acquisition circuit 29 in secondary cabin 1, including LED light group 14, CMOS Sensor 15, microcontroller 10;Hemoglobin Test paper 12 and carcinomebryonic antigen Test paper 13, through hole are included in secondary cabin 23 11 are provided with two, and the test side of hemoglobin Test paper 12 and carcinomebryonic antigen Test paper 13 is pasted onto at two through holes 11, The other end is pasted onto on the inwall in secondary cabin 23.Connected between secondary cabin 1 and secondary cabin 23 and main cabin 1 by degradable retainer ring 16 Fixed, after degradable retainer ring 16 is degraded, separation comes off from main cabin 1 for secondary cabin 1 and secondary cabin 23.
There are two transparent watertight baffle plate 7c, 7 to be individually fixed in secondary cabin 1 and main cabin 1 between main cabin 1 and secondary cabin 1;It is main There are two transparent watertight baffle plates 7a, 7b to be individually fixed in main cabin 1 and secondary cabin 23 between cabin 1 and secondary cabin 23.
The shell in secondary cabin 1 is transparent;Minicell uses three pieces of button cells;LED light group 14 and 14a lampet Number is 2~4, and using paster type light emitting type, color uses white light.
Degradable retainer ring 16 is annularly surrounded on capsule in main cabin 1 and secondary cabin 1, the joint in main cabin 1 and secondary cabin 23 The outside of shell, width are 2~5mm, material selection PVAP.
Energy is transmitted by contact 22 between image acquisition circuit 29 and main cabin 1 and signal, Fig. 4 give the specific of contact Structure, contact 22 include upper connecting rod 23, upper end tactile disk 25, lower end tactile disk 26, lower pull bar 24, pin hole 27 and contact pilotage 28;Touch upper end The thickness of disk 25 is 1.2mm, and the contact area with lower end tactile disk 26 is 6mm2, it is shaped as circle;The thickness of lower end tactile disk 26 and Shape is identical with upper end tactile disk;Pin hole 27 is cylindrical hole, a diameter of 1.1mm, and the highly thickness less than upper end tactile disk 25, number is 2;The contact pilotage 28 is cylinder, and diameter is slightly less than pin hole 27, highly identical with pin hole or slightly above pin hole, number and position Distribution is identical with pin hole.
As shown in figure 5, the positive findings schematic diagram of capsule hemoglobin and the carcinomebryonic antigen detection for the present embodiment one, blood Lactoferrin Test paper 12 is made with carcinomebryonic antigen Test paper 13 using colloidal gold immunity chromatography, and specificity is directed to people's blood Lactoferrin and carcinomebryonic antigen, and detection sensitivity is high, if hemoglobin in gastric juice be present, hemoglobin Test paper 12 is shown Two red lines, if being not present, show a red line;Similarly, if there being carcinomebryonic antigen in gastric juice, carcinomebryonic antigen Test paper 13 two red lines of display, if being not present, show a red line.
The course of work of the present embodiment one is as follows:The detachable capsule enters in stomach by oral administration, and gastric juice is by through hole 11 Into secondary cabin 23, hemoglobin Test paper 12 contacts with carcinomebryonic antigen Test paper 13 with gastric juice, and gastric juice is upward along test paper Chromatograph and chromogenic reaction occurs, cmos sensor 15a collects the color change of two test paper, then enters via microcontroller 10a The certain processing of row, is finally sent in vitro by wireless transmitter module 4;Meanwhile image acquisition circuit 29 shoots the figure inside stomach Picture, image information send wireless transmitter module 4 to by contact 22, are sent in vitro by wireless transmitter module 4.Capsule enters small After intestines, degradable retainer ring 16 starts gradually to degrade, and secondary cabin 1 and secondary cabin 23 separate with main cabin 1, forms three independent cabins Body, during capsule separates, image acquisition circuit 29 can still shoot the picture in a part of small intestine, there is provided the inspection of small intestine Information is looked into, until contact 22 is fully disconnected, stops shooting.
Embodiment two
As shown in figure 3, a kind of detachable capsule, including main cabin 1, secondary cabin 1 and secondary cabin 23, the present embodiment two with it is real Apply example one to compare, the structure and implementation method in secondary cabin 23 are just the same, and signal acquisition control circuit 20 is added in main cabin 1;It is secondary The structure in cabin 1 has difference with implementation method;Pass through degradable retainer ring 16 between secondary cabin 1 and secondary cabin 23 and main cabin 1 It is connected, after degradable retainer ring 16 is degraded, separation comes off from main cabin 1 for secondary cabin 1 and secondary cabin 23.
The secondary cabin 1 of the present embodiment two includes absorbent wool 17, pH detection probes 18, pH detection sensors 19 and baffle plate 7d, Baffle plate 7d is transparent or opaque, and pH detection sensors 19 select antimony electrode, and pH detection probes 18 penetrate baffle plate 7d, is injected In absorbent wool 17, baffle plate 7d scribbles marine glue by the place of penetrating of pH detection probes 18;Secondary cabin 1 is provided with through hole 2~4, is easy to stomach Liquid enters secondary cabin 1.
There are two transparent watertight baffle plate 7c, 7 to be individually fixed in secondary cabin one and main cabin between main cabin 1 and secondary cabin 1;Main cabin There are two transparent watertight baffle plates 7a, 7b to be individually fixed in main cabin 1 and secondary cabin 23 between 1 and secondary cabin 23.
Degradable retainer ring 16 is annularly surrounded on capsule in main cabin 1 and secondary cabin 1, the joint in main cabin 1 and secondary cabin 23 The outside of shell, width are 2~5mm, material selection PVAP.
Energy and signal, the concrete structure and reality of contact are transmitted by contact 22 between pH detection sensors 19 and main cabin 1 Existing method is identical with embodiment one.
The course of work of the present embodiment two is as follows:Person under inspection is taken into detachable capsule with warm water, capsule enter stomach and Start working, secondary one end of cabin 1, gastric juice is entered by through hole 11, soaks absorbent wool 17, it is concurrent that pH detection probes 18 contact gastric juice Biochemical reaction, potential is produced, changes into voltage signal via pH detection sensors 19, passing to signal by contact 22 adopts Collect control circuit 20, then be sent in vitro via wireless transmitter module 4;Secondary one end of cabin 23, gastric juice are entered by through hole 11, connect The test side of hemoglobin Test paper 12 and carcinomebryonic antigen Test paper 13 is contacted, gastric juice is chromatographed and occurred upwards along test paper Chromogenic reaction, cmos sensor 15a collect the color change of two test paper, and certain processing is carried out by microcontroller 10a, then It is sent in vitro by wireless transmitter module 4.
The present invention is not limited to above-mentioned embodiment, according to the above, according to the ordinary technical knowledge of this area And customary means, under the premise of the above-mentioned basic fundamental thought of the present invention is not departed from, the present invention can also make other diversified forms Equivalent modifications, replacement or change, all fall among protection scope of the present invention.

Claims (9)

  1. A kind of 1. separate type capsule, it is characterised in that the capsule includes main cabin (1), secondary cabin one (2) and secondary cabin two (3), its In, main cabin (1) includes wireless transmitter module (4), minicell (5), energy supply control module (6), signal acquisition control circuit (8) image acquisition circuit (29), is included in secondary cabin one (2), gastric juice detection sensor (9), described image are included in secondary cabin two (3) Acquisition Circuit (29) includes LED light group (14), cmos sensor (15) and microcontroller (10);Secondary cabin one (2) and secondary cabin two (3) It is connected between main cabin (1) by degradable retainer ring (16), after degradable retainer ring (16) degraded, secondary cabin one (2) Come off with secondary cabin two (3) from main cabin (1);
    There are two transparent watertight baffle plates, baffle plate four (7c) and baffle plate one (7), baffle plate four between the main cabin (1) and secondary cabin one (2) (7c) is fixed in secondary cabin one (2), and baffle plate one (7) is fixed in main cabin (1);There are two between main cabin (1) and secondary cabin two (3) thoroughly Bright water bar, baffle plate two (7a) and baffle plate three (7b), baffle plate two (7a) are fixed in main cabin (1), and baffle plate three (7b) is fixed on In secondary cabin two (3).
  2. 2. separate type capsule according to claim 1, it is characterised in that the degradable retainer ring (16) is in main cabin (1) Annularly it is surrounded on the outside of capsule shell with the joint of secondary cabin one (2), main cabin (1) and secondary cabin two (3), width is 2~ 5mm, material are degradation material, the one kind being chosen in particular from following material:Shellac, PVAP, third Olefin(e) acid resin, cellulose acetate phthalate, Hydroxypropyl Methylcellulose Phathalate, PLA.
  3. 3. separate type capsule according to claim 1, it is characterised in that described image Acquisition Circuit (29) and main cabin (1) Between pass through wire (21) or contact (22) and transmit energy and signal.
  4. 4. separate type capsule according to claim 1, it is characterised in that the gastric juice detection sensor (9) is adopted with signal Signal connected mode between collection control circuit (8) has two kinds:Wireless connection and wired connection;
    Wireless connection:Signal acquisition control circuit (8) gathers optical signal or image information or electromagnetic information, is connected without conductor;
    Wired connection:Connected by wire (21) or contact (22).
  5. 5. the separate type capsule according to claim 3 or 4, it is characterised in that wire (21) material is aluminium, and length is 5~20mm, a diameter of 0.5~1.5mm, wire (21) penetrate two baffle plates of the baffle plate one (7a) and baffle plate four (7c), and The surface for penetrating the baffle plate one (7a) and baffle plate four (7c) scribbles marine glue.
  6. 6. the separate type capsule according to claim 3 or 4, it is characterised in that the contact (22) include upper connecting rod (23), Upper end tactile disk (25), lower end tactile disk (26), lower pull bar (24), pin hole (27) and contact pilotage (28), contact (22) penetrate the baffle plate Two baffle plates of two (7a) and baffle plate three (7b), and scribble waterproof on the surface for penetrating the baffle plate two (7a) and baffle plate three (7b) Glue.
  7. 7. separate type capsule according to claim 1, it is characterised in that nacelle where described image Acquisition Circuit (29) Shell is transparent.
  8. 8. separate type capsule according to claim 1, it is characterised in that the gastric juice detection sensor (9) is tried for detection Paper or reagent or electrode or more any combination;
    Test paper is selected from following one or more:Hemoglobin Test paper, transferrins Test paper, H. pylori Bacterium Test paper and carcinomebryonic antigen Test paper;
    Detecting electrode is selected from following one or more:PH detecting electrodes, hemoglobin detecting electrode and temperature detection electrode.
  9. 9. separate type capsule according to claim 1, it is characterised in that the signal acquisition control circuit (8) is gathered Signal be signals below form one or more:Picture signal, digitally encoded signal, optical signal, current signal, voltage letter Number, pressure signal, electromagnetic signal.
CN201610854105.2A 2016-09-27 2016-09-27 A kind of separate type capsule Active CN106361254B (en)

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107212846A (en) * 2017-08-07 2017-09-29 杨露 A kind of gastric acid detecting device of gastroscope connection
CN108720794B (en) * 2018-06-08 2023-09-08 苏州市启献智能科技有限公司 Electrically-actuated safety disintegration capsule gastroscope
CN118787385A (en) * 2019-11-29 2024-10-18 重庆大学 Gastric juice sampling capsule
CN110916600B (en) * 2019-12-02 2021-12-14 郑州大学第一附属医院 Capsule endoscope capable of being automatically separated and combined
CN115251807B (en) * 2022-09-26 2022-12-06 徐州医科大学 Capsule endoscope system

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Publication number Priority date Publication date Assignee Title
CN2550764Y (en) * 2002-07-03 2003-05-14 刘万水 Gastric juice detector
US7647090B1 (en) * 2003-12-30 2010-01-12 Given Imaging, Ltd. In-vivo sensing device and method for producing same
WO2005062717A2 (en) * 2003-12-31 2005-07-14 Given Imaging Ltd. In-vivo sensing device with detachable part
CN101721194B (en) * 2008-10-14 2011-11-09 鸿富锦精密工业(深圳)有限公司 Capsule endoscope and method for manufacturing lenses thereof
CN102631183A (en) * 2012-05-03 2012-08-15 重庆大学 Novel intellectual detection system of gastric fluid occult blood

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