CN106361254A - Separable capsule - Google Patents

Separable capsule Download PDF

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Publication number
CN106361254A
CN106361254A CN201610854105.2A CN201610854105A CN106361254A CN 106361254 A CN106361254 A CN 106361254A CN 201610854105 A CN201610854105 A CN 201610854105A CN 106361254 A CN106361254 A CN 106361254A
Authority
CN
China
Prior art keywords
cabin
main cabin
capsule
signal
separate type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610854105.2A
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Chinese (zh)
Other versions
CN106361254B (en
Inventor
乔盼盼
刘洪英
皮喜田
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Chongqing University
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Chongqing University
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Priority to CN201610854105.2A priority Critical patent/CN106361254B/en
Publication of CN106361254A publication Critical patent/CN106361254A/en
Application granted granted Critical
Publication of CN106361254B publication Critical patent/CN106361254B/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041Capsule endoscopes for imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661Endoscope light sources
    • A61B1/0684Endoscope light sources using light emitting diodes [LED]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4261Evaluating exocrine secretion production
    • A61B5/4283Evaluating exocrine secretion production gastrointestinal secretions, e.g. bile production

Abstract

The invention provides a separable capsule for detecting a disease marker in gastric fluid and acquiring a real image of the stomach. The separable capsule comprises a main cabin, an auxiliary cabin I and an auxiliary cabin II, wherein the main cabin comprises a wireless emission module, a micro battery, a power control module and a signal acquisition and control circuit; the auxiliary cabin I comprises an image acquisition image or a gastric fluid detection sensor; the auxiliary cabin II comprises an image acquisition circuit or a gastric fluid detection sensor; each image acquisition circuit comprises an LED lamp group, a CMOS sensor and a micro controller; the auxiliary cabin I and the auxiliary cabin II are connected and fixed with the main cabin through degradable fixing rings; after the degradable fixing rings are degraded, the auxiliary cabin I and the auxiliary cabin II are separated from the main cabin. The separable capsule provided by the invention can take a picture of a gastrointestinal wall and can also detect various disease markers; after the detection is completed, the two auxiliary cabins of the capsule are separated from the main cabin, so that the total size of the capsule is decreased, and the risk that the capsule cannot be discharged after entering a human body is effectively reduced.

Description

A kind of separate type capsule
Technical field
The present invention relates to medicinal detection device, specifically a kind of detachable capsule, by capsule of eating, detect gastrointestinal tract Disease.
Background technology
On clinical medicine, the diagnosis of gastropathy mostly from the beginning of the detection of gastric juice, at present, extract gastric juice major way by In gastroscope, optical microscope is carried out taking liquid to operate from oral cavity insertion stomach, patient suffering is big, although using cooperatively anesthetics, But still misery is unbearably, and gastroscope also can only extract gastric juice, and other checked operations are to carry out in vitro.
Propose a kind of gastric juice detector in patent cn02268048, with lead, Test paper is bundled into reagent paper group, examination Spitball is wrapped in solubility big envelope, and the end of lead is placed in outside solubility big envelope.Although patient is easy to use, on the one hand cure Raw workload is big, when another aspect person under inspection takes reagent paper group, when staying the fine rule of outside and pulling out capsule, can produce evil The discomfort such as the heart, vomiting, and unhygienic convenience.
A kind of Novel intellectual detection system of gastric fluid occult blood is proposed, this gastric juice is occulted blood capsule in patent cn201210134190 The main gastric juice that includes is occulted blood detection module, imageing sensor, microprocessor, signal wireless transmitter module etc., and gastric juice is occulted blood detection Module detection gastric juice is occulted blood situation assume color change, and imageing sensor acquisition testing result images information, through microprocessor Launched to external by signal wireless transmitter module after process.Using this capsule of occulting blood, experimenter carry out gastric juice occult blood examination when no Wound, painless.But due to detecting the restriction of end spaces, the detection mark of this capsule system only only have stomach occult blood one kind it is impossible to Detection has a certain distance for focusing between multiple markers, and imageing sensor and Test paper simultaneously, occupies capsule Interior much room.
Content of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of detachable capsule, the disease in the middle of detection gastric juice Sick mark, and obtain the true picture of stomach simultaneously, accuracy simple to operate, easy to use, disease detection is high;Capsule cabin After body separates, overall volume diminishes, and is easy to excrete, and substantially reduces the risk of capsule detection.
Technical scheme:
Detachable capsule, including main cabin, secondary cabin one and secondary cabin two, main cabin includes wireless transmitter module, minicell, electricity Source control module, signals collecting control circuit;Image acquisition circuit or gastric juice detection sensor is comprised, in secondary cabin two in secondary cabin one Comprise image acquisition circuit or gastric juice detection sensor, described image Acquisition Circuit includes LED lamp group, cmos sensor and micro-control Device processed;It is connected by degradable retainer ring between secondary cabin one and secondary cabin two and main cabin, after the degraded of degradable retainer ring, secondary Cabin one separates from main cabin with secondary cabin two and comes off.
Two transparent watertight baffle plates are had to be individually fixed in secondary cabin one and main cabin between main cabin and secondary cabin one;Main cabin and secondary cabin Two transparent watertight baffle plates are had to be individually fixed in main cabin and secondary cabin two between two.
The shell of described image Acquisition Circuit place nacelle is transparent;The nacelle that gastric juice detection sensor is located has logical Hole, enables gastric juice to enter;Minicell adopts three pieces of button cells;The lampet number of LED lamp group 14 is 2~4, using patch Flat type LED, color adopts white light.
Described degradable retainer ring is annularly surrounded on outside capsule with secondary cabin one, main cabin and the joint in secondary cabin two in main cabin The outside of shell, width is 2~5mm, and material is degradation material, is chosen in particular from one of following material: Lac, polyvinyl alcohol Acetate phthalate ester, acrylic resin, cellulose acetate phthalate, Hydroxypropyl Methylcellulose Phathalate, poly- Lactic acid.
Pass through wire between described image Acquisition Circuit and main cabin or energy and signal are transmitted in contact.
Wired or wireless connection, wherein wired company is adopted between described gastric juice detection sensor and signals collecting control circuit It is connected in wire to connect or contact portion;During wireless connection, the signal that signals collecting control circuit is gathered is optical signal or image Information or electromagnetic information.
Described wire connects, and conductor material is aluminum, can be decomposed by gastric acid, and length is 5~20mm, a diameter of 0.5~ 1.5mm, wire penetrates two baffle plates, and scribbles marine glue on the surface penetrating baffle plate;Described contact also through two baffle plates, and And in two baffle plates, the surface smear marine glue at place is penetrated by contact.
Contact includes upper connecting rod, upper end tactile disk, lower end tactile disk, lower pull bar, pin hole and contact pilotage;The thickness of upper end tactile disk is 0.5~2mm, the contact area with lower end tactile disk is 2~12mm2, generally circular in shape or oval or rectangle or rhombus or trapezoidal; The thickness of lower end tactile disk is identical with upper end tactile disk with shape;Pin hole is cylindrical hole, a diameter of 1~2mm, is highly less than upper end tactile disk Thickness, number be 1~3;Described contact pilotage is cylinder, and diameter is slightly less than pin hole, highly identical with pin hole or slightly above pin Hole, number and position distribution are identical with pin hole.
Gastric juice detection sensor is Test paper or reagent or electrode or more combination in any;Test paper is selected from following One or more: hemoglobin Test paper, transferrinss Test paper, detecting paper for pylorus spiral bacillus and carcinoembryonic antigen Test paper;Detecting electrode is selected from following one or more: ph detecting electrode, hemoglobin detecting electrode and temperature detection Electrode.
The signal that signals collecting control circuit is gathered is one or more of signals below form: picture signal, numeral Encoded signal, optical signal, current signal, voltage signal, pressure signal, electromagnetic signal.
The work process of the present invention:
Described detachable capsule enters gastric by oral administration, and gastric juice enters secondary cabin, gastric juice detection sensor and stomach by through hole Liquid contacts, the information of detection disease of stomach mark, and signals collecting control circuit gathers and processes the detection of gastric juice detection sensor The information arriving, is then transferred to by wireless transmitter module in vitro;Meanwhile, image acquisition circuit shoots the image within stomach, figure As information sends wireless transmitter module to by wire or contact, it is transferred in vitro by wireless transmitter module.Capsule enters small intestinal Afterwards, degradable retainer ring starts gradually to degrade, and secondary cabin one is separated with main cabin with secondary cabin two, forms three independent nacelle, in glue During capsule is detached, image acquisition circuit still can gather the picture in a part of small intestinal, provides the inspection information of small intestinal, directly It is fully disconnected to contact, stop shooting
Detachable capsule provided by the present invention, after detection completes, two secondary cabins of capsule are separated with main cabin, make glue Capsule cumulative volume diminishes, and effectively reduces capsule and enters the risk that human body cannot be discharged;Detachable capsule provided by the present invention is not The picture of gastrointestinal wall only can be shot, can also non-invasively detect the disease marker in gastric juice, and multiple marks can be detected simultaneously Will thing, accuracy simple to operate, easy to use, disease detection is high.
Brief description:
Fig. 1 is the structural representation of separate type capsule of the present invention;
Fig. 2 is the separate type capsule structure schematic diagram of the embodiment of the present invention one;
Fig. 3 is the separate type capsule structure schematic diagram of the embodiment of the present invention two;
Fig. 4 is contact structure schematic diagram;
Fig. 5 is the sun of hemoglobin Test paper and carcinoembryonic antigen Test paper in the embodiment of the present invention one and embodiment two Property result schematic diagram.
In Fig. 1 to Fig. 5:
The main cabin of 1 ━, 2 ━ pair cabins one, 3 ━ pair cabins two, 4 ━ wireless transmitter modules, 5 ━ minicells, 6 ━ power supply moulds Block, 7 ━ baffle plates, 7a ━ baffle plate, 7b ━ baffle plate, 7c ━ baffle plate, 7d ━ baffle plate, 8 ━ signals collecting control circuits, 9 ━ gastric juice inspections Survey sensor, 10 ━ microcontrollers, 10a ━ microcontroller, 11 ━ through holes, 12 ━ hemoglobin Test papers, 13 ━ cancer embryos resist Former Test paper, 14 ━ LED lamp groups, 14a ━ LED lamp group, 15 ━ cmos sensors, 15a ━ cmos sensor, 16 ━ degradables Retainer ring, 17 ━ absorbent cottons, 18 ━ ph detection probes, 19 ━ ph detection sensors, 20 ━ signals collecting control circuits, 21 ━ lead Line, 22 ━ contacts, 23 ━ upper connecting rods, pull bar, 25 ━ upper end tactile disks, 26 ━ lower end tactile disks, 27 ━ pin holes, 28 ━ touch under 24 ━ Pin, 29 ━ image acquisition circuit.
Specific embodiment
Embodiment one
As shown in Fig. 2 a kind of detachable capsule, including main cabin 1, secondary cabin 1 and secondary cabin 23, main cabin 1 includes wireless sending out Penetrate module 4, minicell 5, energy supply control module 6, signals collecting control circuit 8, signals collecting control circuit 8 includes LED lamp Group 14a, cmos sensor 15a, microcontroller 10a;It is image acquisition circuit 29 in secondary cabin 1, including LED lamp group 14, cmos Sensor 15, microcontroller 10;Hemoglobin Test paper 12 and carcinoembryonic antigen Test paper 13, through hole is comprised in secondary cabin 23 11 are provided with two, and the test side of hemoglobin Test paper 12 and carcinoembryonic antigen Test paper 13 is pasted onto at two through holes 11, The other end is pasted onto on the inwall in secondary cabin 23.It is connected by degradable retainer ring 16 between secondary cabin 1 and secondary cabin 23 and main cabin 1 Fixing, after degradable retainer ring 16 degraded, secondary cabin 1 and secondary cabin 23 separate from main cabin 1 and come off.
There are two transparent watertight baffle plate 7c between main cabin 1 and secondary cabin 1,7 be individually fixed in secondary cabin 1 and main cabin 1;Main Two transparent watertight baffle plate 7a, 7b are had to be individually fixed in main cabin 1 and secondary cabin 23 between cabin 1 and secondary cabin 23.
The shell in secondary cabin 1 is transparent;Minicell adopts three pieces of button cells;The lampet of LED lamp group 14 and 14a Number is 2~4, and using paster type light emitting type, color adopts white light.
Degradable retainer ring 16 is annularly surrounded on capsule in main cabin 1 with secondary cabin 1, main cabin 1 and the joint in secondary cabin 23 The outside of shell, width is 2~5mm, material selection PVAP.
Between image acquisition circuit 29 and main cabin 1, energy and signal are transmitted by contact 22, Fig. 4 gives the concrete of contact Structure, contact 22 includes upper connecting rod 23, upper end tactile disk 25, lower end tactile disk 26, lower pull bar 24, pin hole 27 and contact pilotage 28;Upper end is touched The thickness of disk 25 is 1.2mm, and the contact area with lower end tactile disk 26 is 6mm2, generally circular in shape;The thickness of lower end tactile disk 26 and Shape is identical with upper end tactile disk;Pin hole 27 is cylindrical hole, a diameter of 1.1mm, is highly less than the thickness of upper end tactile disk 25, and number is 2;Described contact pilotage 28 is cylinder, and diameter is slightly less than pin hole 27, highly identical with pin hole or slightly above pin hole, number and position Distribution is identical with pin hole.
As shown in figure 5, being the capsule hemoglobin of the present embodiment one and the positive findingses schematic diagram of carcinoembryonic antigen detection, blood Lactoferrin Test paper 12 and carcinoembryonic antigen Test paper 13 are all made using colloidal gold immunity chromatography, and specificity is directed to human blood Lactoferrin and carcinoembryonic antigen, and detection sensitivity is high, if there is hemoglobin in gastric juice, hemoglobin Test paper 12 shows Article two, red line, if not existing, shows a red line;In the same manner, if there being carcinoembryonic antigen in gastric juice, carcinoembryonic antigen Test paper 13 two red lines of display, if not existing, show a red line.
The work process of the present embodiment one is as follows: described detachable capsule enters gastric by oral administration, and gastric juice is by through hole 11 Enter secondary cabin 23, hemoglobin Test paper 12 is contacted with gastric juice with carcinoembryonic antigen Test paper 13, and gastric juice is along reagent paper upwards Chromatograph and occur chromogenic reaction, cmos sensor 15a collects the color change of two reagent paper, then enters via microcontroller 10a The certain process of row, is finally sent to by wireless transmitter module 4 in vitro;Meanwhile, image acquisition circuit 29 shoots the figure within stomach Picture, image information sends wireless transmitter module 4 to by contact 22, is sent in vitro by wireless transmitter module 4.Capsule enters little After intestinal, degradable retainer ring 16 starts gradually to degrade, and secondary cabin 1 and secondary cabin 23 are separated with main cabin 1, form three independent cabins Body, during capsule is detached, image acquisition circuit 29 still can shoot the picture in a part of small intestinal, provides the inspection of small intestinal Look into information, until contact 22 is fully disconnected, stop shooting.
Embodiment two
As shown in figure 3, a kind of detachable capsule, including main cabin 1, secondary cabin 1 and secondary cabin 23, the present embodiment two and reality Apply example one to compare, the structure in secondary cabin 23 is just the same with implementation method, in main cabin 1, increased signals collecting control circuit 20;Secondary The structure in cabin 1 and implementation method have difference;Pass through degradable retainer ring 16 between secondary cabin 1 and secondary cabin 23 and main cabin 1 It is connected, after degradable retainer ring 16 degraded, secondary cabin 1 and secondary cabin 23 separate from main cabin 1 and come off.
The secondary cabin 1 of the present embodiment two includes absorbent cotton 17, ph detection probe 18, ph detection sensor 19 and baffle plate 7d, Baffle plate 7d is transparent or opaque, and ph detection sensor 19 selects antimony electrode, and ph detection probe 18 penetrates baffle plate 7d, injects In absorbent cotton 17, baffle plate 7d is scribbled marine glue by ph detection probe 18 place of penetrating;Secondary cabin 1 is provided with through hole 2~4, is easy to stomach Liquid enters secondary cabin 1.
There are two transparent watertight baffle plate 7c between main cabin 1 and secondary cabin 1,7 be individually fixed in secondary cabin one and main cabin;Main cabin Two transparent watertight baffle plate 7a, 7b are had to be individually fixed in main cabin 1 and secondary cabin 23 between 1 and secondary cabin 23.
Degradable retainer ring 16 is annularly surrounded on capsule in main cabin 1 with secondary cabin 1, main cabin 1 and the joint in secondary cabin 23 The outside of shell, width is 2~5mm, material selection PVAP.
Between ph detection sensor 19 and main cabin 1, energy and signal, the concrete structure of contact and reality are transmitted by contact 22 Existing method is identical with embodiment one.
The work process of the present embodiment two is as follows: person under inspection takes into detachable capsule with warm water, capsule enter stomach and Start working, secondary cabin 1 one end, gastric juice is entered by through hole 11, soaks absorbent cotton 17, and ph detection probe 18 contact gastric juice is concurrent Biochemical reaction, produces potential, changes into voltage signal via ph detection sensor 19, pass to signal through contact 22 and adopt Collection control circuit 20, then be sent in vitro via wireless transmitter module 4;Secondary cabin 23 one end, gastric juice is entered by through hole 11, connects Contact hemoglobin Test paper 12 and the test side of carcinoembryonic antigen Test paper 13, gastric juice chromatographs upwards along reagent paper and occurs Chromogenic reaction, cmos sensor 15a collects the color change of two reagent paper, carries out certain process by microcontroller 10a, then It is sent in vitro by wireless transmitter module 4.
The present invention is not limited to above-mentioned specific embodiment, according to the above, according to the ordinary technical knowledge of this area And customary means, under the premise of without departing from the present invention above-mentioned basic fundamental thought, the present invention can also make other various ways Equivalent modifications, replacement or change, all fall among protection scope of the present invention.

Claims (10)

1. a kind of separate type capsule is it is characterised in that described capsule includes main cabin (1), secondary cabin one (2) and pair cabin two (3), its In, main cabin (1) includes wireless transmitter module (4), minicell (5), energy supply control module (6), signals collecting control circuit (8), comprise image acquisition circuit (29) or gastric juice detection sensor (9) in secondary cabin one (2), comprise image in secondary cabin two (3) and adopt Collector (29) or gastric juice detection sensor (9), described image Acquisition Circuit (29) includes LED lamp group (14), cmos sensor And microcontroller (10) (15);It is connected by degradable retainer ring (16) between secondary cabin one (2) and secondary cabin two (3) and main cabin (1) Fixing, after degradable retainer ring (16) degraded, secondary cabin one (2) and secondary cabin two (3) come off from main cabin (1).
2. separate type capsule according to claim 1 is it is characterised in that described degradable retainer ring (16) is in main cabin (1) Annularly it is surrounded on the outside of capsule shell with the joint in secondary cabin one (2), main cabin (1) and secondary cabin two (3), width is 2~ 5mm, material is degradation material, is chosen in particular from one of following material: Lac, PVAP, third Olefin(e) acid resin, cellulose acetate phthalate, Hydroxypropyl Methylcellulose Phathalate, polylactic acid.
3. separate type capsule according to claim 1 is it is characterised in that have two between described main cabin (1) and secondary cabin one (2) Individual transparent watertight baffle plate (7c) and (7), baffle plate (7c) is fixed in secondary cabin one (2), and baffle plate (7) is fixed in main cabin (1);Main cabin (1) there are two transparent watertight baffle plates (7a) and (7b) and secondary cabin two (3) between, baffle plate (7a) is fixed in main cabin (1), baffle plate (7b) it is fixed in secondary cabin two (3).
4. separate type capsule according to claim 1 is it is characterised in that described image Acquisition Circuit (29) and main cabin (1) Between transmit energy and signal by wire (21) or contact (22).
5. separate type capsule according to claim 1 is it is characterised in that described gastric juice detection sensor (9) is adopted with signal Signal connected mode between collection control circuit (8) has two kinds: wireless connection and wired connection;
Wireless connection: signals collecting control circuit (8) collection optical signal or image information or electromagnetic information, connect without conductor;
Wired connection: connected by wire (21) or contact (22).
6. it is characterised in that described wire (21) material is aluminum, length is the separate type capsule according to claim 4 and 5 5~20mm, a diameter of 0.5~1.5mm, wire (19) penetrates two baffle plates, and scribbles marine glue on the surface penetrating baffle plate.
7. the separate type capsule according to claim 4 and 5 it is characterised in that described contact (22) include upper connecting rod (23), Upper end tactile disk (25), lower end tactile disk (26), lower pull bar (24), pin hole (27) and contact pilotage (28), contact (20) penetrate two baffle plates, And scribble marine glue on the surface penetrating baffle plate.
8. separate type capsule according to claim 1 is it is characterised in that described image Acquisition Circuit (29) place nacelle Shell is transparent.
9. separate type capsule according to claim 1 is it is characterised in that described gastric juice detection sensor (9) is detection examination Paper or reagent or electrode or more combination in any;
Test paper is selected from following one or more: hemoglobin Test paper, transferrinss Test paper, H. pylori Bacterium Test paper and carcinoembryonic antigen Test paper;
Detecting electrode is selected from following one or more: ph detecting electrode, hemoglobin detecting electrode and temperature detection electrode.
10. separate type capsule according to claim 1 is it is characterised in that described signals collecting control circuit (8) is gathered Signal be signals below form one or more: picture signal, digitally encoded signal, optical signal, current signal, voltage letter Number, pressure signal, electromagnetic signal.
CN201610854105.2A 2016-09-27 2016-09-27 A kind of separate type capsule Active CN106361254B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107212846A (en) * 2017-08-07 2017-09-29 杨露 A kind of gastric acid detecting device of gastroscope connection
CN108720794A (en) * 2018-06-08 2018-11-02 苏州市奇捷生物科技有限公司 A kind of electric actuation safety solution body capsule gastroscope
CN110916600A (en) * 2019-12-02 2020-03-27 郑州大学第一附属医院 Capsule endoscope capable of being automatically separated and combined
CN115251807A (en) * 2022-09-26 2022-11-01 徐州医科大学 Capsule endoscope system

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CN2550764Y (en) * 2002-07-03 2003-05-14 刘万水 Gastric juice detector
US20070282164A1 (en) * 2003-12-31 2007-12-06 Mordechai Frisch In-Vivo Sensing Device With Detachable Part
US7647090B1 (en) * 2003-12-30 2010-01-12 Given Imaging, Ltd. In-vivo sensing device and method for producing same
CN101721194A (en) * 2008-10-14 2010-06-09 鸿富锦精密工业(深圳)有限公司 Capsule endoscope and method for manufacturing lenses thereof
CN102631183A (en) * 2012-05-03 2012-08-15 重庆大学 Novel intellectual detection system of gastric fluid occult blood

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2550764Y (en) * 2002-07-03 2003-05-14 刘万水 Gastric juice detector
US7647090B1 (en) * 2003-12-30 2010-01-12 Given Imaging, Ltd. In-vivo sensing device and method for producing same
US20070282164A1 (en) * 2003-12-31 2007-12-06 Mordechai Frisch In-Vivo Sensing Device With Detachable Part
CN101721194A (en) * 2008-10-14 2010-06-09 鸿富锦精密工业(深圳)有限公司 Capsule endoscope and method for manufacturing lenses thereof
CN102631183A (en) * 2012-05-03 2012-08-15 重庆大学 Novel intellectual detection system of gastric fluid occult blood

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107212846A (en) * 2017-08-07 2017-09-29 杨露 A kind of gastric acid detecting device of gastroscope connection
CN108720794A (en) * 2018-06-08 2018-11-02 苏州市奇捷生物科技有限公司 A kind of electric actuation safety solution body capsule gastroscope
CN108720794B (en) * 2018-06-08 2023-09-08 苏州市启献智能科技有限公司 Electrically-actuated safety disintegration capsule gastroscope
CN110916600A (en) * 2019-12-02 2020-03-27 郑州大学第一附属医院 Capsule endoscope capable of being automatically separated and combined
CN115251807A (en) * 2022-09-26 2022-11-01 徐州医科大学 Capsule endoscope system

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