CN106344044A - Partially separable smart capsule - Google Patents
Partially separable smart capsule Download PDFInfo
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- CN106344044A CN106344044A CN201610854129.8A CN201610854129A CN106344044A CN 106344044 A CN106344044 A CN 106344044A CN 201610854129 A CN201610854129 A CN 201610854129A CN 106344044 A CN106344044 A CN 106344044A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4222—Evaluating particular parts, e.g. particular organs
- A61B5/4238—Evaluating particular parts, e.g. particular organs stomach
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4261—Evaluating exocrine secretion production
- A61B5/4283—Evaluating exocrine secretion production gastrointestinal secretions, e.g. bile production
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6871—Stomach
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- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
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- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Physiology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention provides a partially separable smart capsule. The partially separable smart capsule comprises a main chamber, a reaction chamber, a battery chamber and two fixing rings, wherein a power control module, a wireless transmission module, a signal acquisition circuit and two baffles I are arranged in the main chamber; a baffle II, a gastric juice detection sensor and through holes are arranged in the reaction chamber; a miniature battery and a baffle III are arranged in the battery chamber; the gastric juice detection sensor is used for detecting a disease marker in gastric juice and detecting multiple markers simultaneously; the two fixing rings can be made of degradable materials, the miniature battery and the power control module are connected through a contact or a resolvable wire, and the gastric juice detection sensor is wirelessly connected with the signal acquisition circuit; under the condition that the two fixing rings are both made of the degradable materials, the battery chamber and the reaction chamber can be separated after the smart capsule finishes detection in the stomach, the whole capsule is resolved into three parts, the length of the whole capsule is shortened greatly, and the risk that the capsule enters a human body but cannot be discharged can be reduced effectively.
Description
Technical field
The present invention relates to medicinal detection device, specifically a kind of intelligent capsule being partially disengaged, by capsule of eating, examine
Survey disease of stomach.
Background technology
At present, on clinical medicine, the diagnostic method main flow of disease of stomach is gastroscope, but gastroscopy whole operation process is given
Person under inspection brings certain painful even wound, makes people there is certain feared state of mind for gastroscopy, in order to reach no
Wound detection, capsule endoscope is gradually applied to clinic.But because capsule endoscope is passively to move, thus detection position under one's belt
Limited to very much although the active capsule endoscope being much exclusively used in stomach is suggested, but big all in conceptual phase, and be
Gastric carries out shooting to diagnose the illness, and specially gastric juice is not analyzed to diagnose the intelligent capsule of disease of stomach.
Propose a kind of Novel intellectual detection system of gastric fluid occult blood in Chinese patent cn201210134190, this system bag
Include gastric juice to occult blood detection capsule, external portable receiver display device, gastric juice detection capsule of occulting blood mainly includes gastric juice and occults blood inspection
Survey module, imageing sensor, microprocessor, signal wireless transmitter module etc., gastric juice detection module detection gastric juice of occulting blood is occulted blood feelings
Condition simultaneously assumes color change, imageing sensor acquisition testing result images information, is wirelessly sent out by signal after microprocessor processes
Penetrate module and launch and carry out wireless receiving, storage and display to external portable receiver display device, and moved in vain by special algorithm
Identification gastric juice is occulted blood information, health care worker or patient according to the display module in external portable receiver display device or
Alarm module judges that gastric whether there is and occults blood.Using this detection capsule of occulting blood, experimenter carry out gastric juice occult blood examination when noinvasive,
Painless.But this capsule system detection project is single, it is only used for detecting occulting blood in gastric juice, and imageing sensor and Test paper
Between have a certain distance for focusing on, occupy the much room in capsule.
Content of the invention
It is an object of the invention to provide a kind of intelligent capsule being partially disengaged, the disease marker in the middle of detection gastric juice,
Two to three parts can be detached into after the completion of capsule detection, length be greatly reduced, is easy to excrete, reduce capsule detection wind
Danger.
Technical scheme:
The intelligent capsule that can be partially disengaged, including main cabin, reaction cabin, battery flat and two retainer ring, wherein, main cabin Nei Bao
Containing one baffle plate of inclusion, gastric juice inspection in energy supply control module, wireless transmitter module, signal acquisition circuit, two baffle plates, reaction cabin
Survey sensor and through hole, in battery flat, comprise minicell and a baffle plate.
Respectively by main cabin and battery flat, main cabin and reaction cabin couple together described two retainer ring, in nacelle joint are in
Ring-type is surrounded on outside capsule shell, and width is 2～5mm；From material degradable or non-degradable, have four kinds of combination sides
Formula: the retainer ring degradable of battery flat side, the retainer ring degradable of reaction cabin side；The retainer ring of battery flat side can drop
Solution, the retainer ring non-degradable of reaction cabin side；The retainer ring non-degradable of battery flat side, the retainer ring of reaction cabin side can
Degraded；The retainer ring non-degradable of battery flat side, the retainer ring non-degradable of reaction cabin side.
According to four kinds of compound modes of two retainer ring selected materials, the mode that comes off of described battery flat and reaction cabin also has
Four kinds of combinations: battery flat is tear-away, and reaction cabin is tear-away；Battery flat is tear-away, and reaction cabin is not tear-away；Battery flat can not take off
Fall, reaction cabin is tear-away；Battery flat is not tear-away, and reaction cabin is not tear-away.
Degradation material selected by described two retainer ring is selected from one of following material: Lac, polyvinyl alcohol second
Sour phthalic acid ester, acrylic resin, cellulose acetate phthalate, Hydroxypropyl Methylcellulose Phathalate, poly- breast
Acid.
Two baffle plates at described reaction cabin place end are transparent, and two baffle plates at battery flat place end can be transparent
Or opaque.
Described gastric juice detection sensor is Test paper or detecting electrode or a combination of both；Test paper is selected from following
One or more: hemoglobin Test paper, transferrinss Test paper, detecting paper for pylorus spiral bacillus and carcinoembryonic antigen
Test paper；Detecting electrode is selected from following one or more: ph detecting electrode, hemoglobin detecting electrode and temperature detection
Electrode.
The signal that described signal acquisition circuit is gathered is one or more of signals below form: picture signal, numeral
Encoded signal, optical signal, current signal, voltage signal, pressure signal, electromagnetic signal.
Described minicell adopts three pieces of button cells.
Between described minicell and energy supply control module by wire or contact portion.
Wired or wireless connection is adopted, wherein wired connection is between described gastric juice detection sensor and signal acquisition circuit
Wire connects or contact portion；During wireless connection, the signal that signal acquisition circuit is gathered is optical signal or image information or electricity
Magnetic information.
Described wire connects, and conductor material is aluminum, can be decomposed by gastric acid, and length is 5～20mm, a diameter of 0.5～
1.5mm, wire passes through two baffle plates, and is penetrated the surface smear marine glue at place in two baffle plates by wire, prevents gastric juice from entering
Enter nacelle.
Described contact passes through two baffle plates, and is penetrated the surface smear marine glue at place in two baffle plates by contact, prevents
Gastric juice enters nacelle.
Described contact includes upper connecting rod, upper end tactile disk, lower end tactile disk, lower pull bar, pin hole and contact pilotage；The thickness of upper end tactile disk
For 0.5～2mm, the contact area with lower end tactile disk is 2～12mm2, generally circular in shape or oval or rectangle or rhombus or ladder
Shape；The thickness of lower end tactile disk is identical with upper end tactile disk with shape；Pin hole is cylindrical hole, a diameter of 1～2mm, is highly less than upper end
The thickness of tactile disk, number is 1～3；Described contact pilotage is cylinder, and diameter is slightly less than pin hole, highly identical with pin hole or slightly higher
In pin hole, number and position distribution are identical with pin hole.
Four baffle plate diameters in capsule are identical with inside capsule wall, and the excircle glue of baffle plate is fixed on inside capsule wall
Above it is impossible to move.
The work process of the present invention:
The described intelligent capsule being partially disengaged enters gastric by oral administration, and gastric juice enters reaction cabin by through hole, and gastric juice is examined
Survey sensor to contact with gastric juice, the information of detection disease of stomach mark, signal acquisition circuit gathers and processes gastric juice detection and passes
The information that sensor detects, detection information is sent in vitro by wireless transmitter module；After intelligent capsule detection completes, capsule root
The material that adopted according to two retainer ring and be detached into two or three independent nacelle, or do not departed from, then via stomach
The wriggling of intestinal, excretes.
One whole capsule can be resolved into two or three little by the intelligent capsule being partially disengaged provided by the present invention
Nacelle, effectively reduces capsule and enters the risk that human body cannot be discharged；Not by the way of traditional capsule shoots gastrointestinal wall picture,
But disease information is obtained using immunochemistry sensor, and detect multiple marks, increase the reliability of testing result.
Brief description:
Fig. 1 is the intelligent capsule overall architecture schematic diagram that can be partially disengaged；
Fig. 2 is the intelligent capsule structural representation that can be partially disengaged；
Fig. 3 is the wire connection diagram in the main cabin of the intelligent capsule that can be partially disengaged and battery flat；
Fig. 4 is the contact portion schematic diagram in the main cabin of the intelligent capsule that can be partially disengaged and battery flat；
Fig. 5 is the wire connection diagram in the main cabin of the intelligent capsule that can be partially disengaged and reaction cabin；
Fig. 6 is the contact portion schematic diagram in the main cabin of the intelligent capsule that can be partially disengaged and reaction cabin；
Fig. 7 is the concrete structure schematic diagram of contact portion；
The intelligent capsule structural representation that Fig. 8 can be partially disengaged for the embodiment of the present invention；
The intelligent capsule that Fig. 9 can be partially disengaged for the embodiment of the present invention be partially disengaged after design sketch；
Figure 10 is the positive findingses schematic diagram of stigmata analyte detection in embodiment of the present invention gastric juice.
In Fig. 1 to Figure 10:
The main cabin of 1 ━, 2 ━ reaction cabins, 3 ━ battery flats, 4 ━ retainer ring, 4a ━ retainer ring, 5 ━ minicells, 6 ━ power supplys
Control module, 7 ━ wireless transmitter modules, 8 ━ signal acquisition circuits, 9 ━ gastric juice detection sensors, 10 ━ baffle plates, 10a ━ gear
Plate, 10b ━ baffle plate, 10c ━ baffle plate, 11 ━ through holes, 12 ━ hemoglobin Test papers, 13 ━ carcinoembryonic antigen Test papers, 14
━ LED lamp group, 15 ━ cmos sensors, 16 ━ microcontrollers, 17 ━ wires, 18 ━ contacts, 17a ━ wire, 18a ━ contact,
Pull bar under 19 ━ upper connecting rods, 20 ━ upper end tactile disks, 21 ━ lower end tactile disks, 22 ━ pin holes, 23 ━ contact pilotages, 24 ━.
Specific embodiment
As shown in figure 8, a kind of intelligent capsule being partially disengaged, including main cabin 1, reaction cabin 2, battery flat 3, retainer ring 4
With retainer ring 4a, wherein, in main cabin 1, comprise energy supply control module 6, wireless transmitter module 7, microcontroller 16, cmos sensor
15th, LED lamp group 14, baffle plate 10a and baffle plate 10b, in reaction cabin 2, inclusion baffle plate 10c, hemoglobin Test paper 12, cancer embryo resist
Former Test paper 13 and through hole 11, comprise minicell 5 and baffle plate 10 in battery flat 3.
Main cabin 1 and battery flat 3 are connected by retainer ring 4, and main cabin 1 and reaction cabin 2 are connected by retainer ring 4a, retainer ring 4 and 4a
Smear circlewise outside capsule shell in nacelle joint, width is 2～5mm.Retainer ring 4 and 4a select degradable material
Material, specially PVAP.
, all from transparent material, diameter is identical with inside capsule wall for baffle plate 4,4a, 4b, 4c, and excircle glue is fixed on glue
It is impossible to move on capsule inner wall.
Be connected using contact 18 between minicell 5 and energy supply control module 6, contact 18 pass through baffle plate 10 and 10a, two
Baffle plate is scribbled marine glue by the surface at contact 18 place of penetrating.
As shown in fig. 7, contact 18 includes upper connecting rod 19, upper end tactile disk 20, lower end tactile disk 21, lower pull bar 24, pin hole 22 and
Contact pilotage 23；The thickness of upper end tactile disk is 1.2mm, and the contact area with lower end tactile disk is 6mm2, generally circular in shape；Lower end tactile disk
Thickness is identical with upper end tactile disk with shape；Pin hole is cylindrical hole, a diameter of 1.2mm, and highly for 0.9mm, number is 2；Contact pilotage
23 is cylinder, a diameter of 1.1mm, height 1.2mm, and number and position distribution are identical with pin hole 22.
Through hole 11 is set to oval aperture, is easy to gastric juice and flows into capsule, and its major axis is 2～5mm, and short axle is 1～2.5mm,
Number is symmetrical two；Microcontroller 16 adopts control circuit commonly used in the prior art；Minicell 5 adopts three pieces of buttons
Battery；Energy supply control module 6 adopts magnetic control mode, and the lampet number of LED lamp group 14 is 2～4, using SMD light-emitting diodes
Pipe, color adopts white light, and irradiates for astigmatism；Hemoglobin Test paper 12, the test side of carcinoembryonic antigen Test paper 13 are glued
It is attached at two through holes 11, the other end is pasted onto on the inwall of reaction cabin 2.
As shown in Figure 10, be the present embodiment intelligent capsule gastric juice in stigmata analyte detection positive findingses schematic diagram,
Hemoglobin Test paper 12 and carcinoembryonic antigen Test paper 13 are all made using colloidal gold immunity chromatography, and specificity is directed to people
Hemoglobin and carcinoembryonic antigen, and detection sensitivity is high, if there is hemoglobin in gastric juice, hemoglobin Test paper 12 shows
Showing two red lines, if not existing, showing a red line；In the same manner, if there being carcinoembryonic antigen in gastric juice, carcinoembryonic antigen detection examination
Paper 13 shows two red lines, if not existing, shows a red line.
The work process of the present embodiment is as follows: person under inspection takes into the intelligent capsule that can be partially disengaged, capsule enter stomach and
Start working, gastric juice enters reaction cabin 2, the hemoglobin Test paper 12 in reaction cabin 2 and carcinoembryonic antigen inspection by through hole 11
Test paper 13 is contacted with gastric juice, and gastric juice chromatographs and occur along reagent paper chromogenic reaction upwards, and cmos sensor 15 collects two
The color change of reagent paper, then carry out certain process via microcontroller 16, it is sent in vitro by wireless transmitter module 7.Body
Interior intelligent capsule detection completes, and after entering small intestinal, the retainer ring 4 of two degradables and 4a gradually degrade, and eventually disengage from into three
Individual independent nacelle, substantially reduces the length of whole capsule, as shown in figure 9, the intelligence being partially disengaged for the embodiment of the present invention
Capsule be partially disengaged after design sketch.If two red lines in hemoglobin Test paper 12 in testing result, then illustrate
Stomach has bleeding；If two red lines in carcinoembryonic antigen Test paper 13, illustrate that containing a certain amount of cancer embryo in gastric juice resists
Former.
The present invention is not limited to above-mentioned specific embodiment, according to the above, according to the ordinary technical knowledge of this area
And customary means, under the premise of without departing from the present invention above-mentioned basic fundamental thought, the present invention can also make other various ways
Equivalent modifications, replacement or change, all fall among protection scope of the present invention.
Claims (10)
1. a kind of intelligent capsule being partially disengaged it is characterised in that described intelligent capsule include main cabin (1), reaction cabin (2),
Battery flat (3), retainer ring (4) and (4a), wherein, comprise in main cabin (1) energy supply control module (6), wireless transmitter module (7),
Signal acquisition circuit (8), baffle plate (10a) and (10b), include in reaction cabin (2) baffle plate (10c), gastric juice detection sensor (9) with
And through hole (11), comprise minicell (5) and baffle plate (10) in battery flat (3), the material of retainer ring (4) and (4a) is degradable
Material or non-degradable material；After gastric juice detection sensor (9) touches gastric juice, reacted, signal acquisition circuit (8)
Gather and process the information that gastric juice detection sensor (9) detects, be then transferred in vitro via wireless transmitter module (7)；Intelligence
After energy capsule detection completes, all gradually degraded using the retainer ring (4) and (4a) of degradation material, three groups of intelligent capsule
Cabin is become to depart from for three independent tanks.
2. the intelligent capsule being partially disengaged according to claim 1 is it is characterised in that described retainer ring (4) is by main cabin
(1) connect with battery flat (3), main cabin (1) and reaction cabin (2) are connected by retainer ring (4a), and retainer ring (4) and (4a) connect in nacelle
Annularly it is surrounded on the outside of capsule shell, width is 2～5mm at conjunction.
3. the intelligent capsule being partially disengaged according to claim 1 is it is characterised in that described retainer ring (4) and (4a)
Material degradable or non-degradable, compound mode has four kinds；
The first: retainer ring (4) degradable, retainer ring (4a) degradable；
Second: retainer ring (4) degradable, retainer ring (4a) non-degradable；
The third: retainer ring (4) non-degradable, retainer ring (4a) degradable；
4th kind: retainer ring (4) non-degradable, retainer ring (4a) non-degradable.
4. the intelligent capsule being partially disengaged according to claim 3 is it is characterised in that described retainer ring (4) and (4a)
Selected combination of materials has four kinds of modes, corresponding, and the mode that comes off of battery flat (3) and reaction cabin (2) also has four kinds of groups
Conjunction mode:
The first: battery flat (3) is tear-away, and reaction cabin (2) is tear-away；
Second: battery flat (3) is tear-away, reaction cabin (2) is not tear-away；
The third: battery flat (3) is not tear-away, and reaction cabin (2) is tear-away；
4th kind: battery flat (3) is not tear-away, reaction cabin (2) is not tear-away.
5. the intelligent capsule being partially disengaged according to claim 1 is it is characterised in that described retainer ring (4) and (4a)
Selected degradation material is selected from one of following material: Lac, PVAP, acrylic acid tree
Fat, cellulose acetate phthalate, Hydroxypropyl Methylcellulose Phathalate, polylactic acid.
6. the intelligent capsule being partially disengaged according to claim 1 is it is characterised in that described gastric juice detection sensor
(9) it is Test paper or detecting electrode or a combination of both；
Test paper is selected from following one or more: hemoglobin Test paper, transferrinss Test paper, H. pylori
Bacterium Test paper and carcinoembryonic antigen Test paper；
Detecting electrode is selected from following one or more: ph detecting electrode, hemoglobin detecting electrode and temperature detection electrode.
7. the intelligent capsule being partially disengaged according to claim 1 is it is characterised in that described signal acquisition circuit (8)
The signal being gathered be signals below form one or more: picture signal, digitally encoded signal, optical signal, current signal,
Voltage signal, pressure signal, electromagnetic signal.
8. the intelligent capsule being partially disengaged according to claim 1 it is characterised in that described minicell (5) with electricity
Pass through wire (17) between source control module (6) or contact (18) connect；Described gastric juice detection sensor (9) and signals collecting electricity
Signal connected mode between road (8) has two kinds: wireless connection and wired connection；
Wireless connection: signal acquisition circuit (8) collection optical signal or image information or electromagnetic information, connect without conductor；
Wired connection: connected by wire (17a) or contact (18a).
9. the intelligent capsule being partially disengaged according to claim 8 is it is characterised in that described wire (17) and (17a)
Material be aluminum, length be 5～20mm, a diameter of 0.5～1.5mm, wire (17) pass through baffle plate (10) and (10a), two keep off
Plate is scribbled marine glue by the surface at wire (17) place of penetrating；Wire (17a) passes through baffle plate (10b) and (10c), and two baffle plates are led
The surface at line (17a) place of penetrating scribbles marine glue.
10. the intelligent capsule being partially disengaged according to claim 8 is it is characterised in that described contact (18) and (18a)
Structure is identical, including upper connecting rod (19), upper end tactile disk (20), lower end tactile disk (21), lower pull bar (24), pin hole (22) and contact pilotage
(23), contact (18) pass through baffle plate (10) and (10a), and two baffle plates are scribbled marine glue by the surface at contact (18) place of penetrating；Lead
Line (18a) passes through baffle plate (10b) and (10c), and two baffle plates are scribbled marine glue by the surface at contact (18a) place of penetrating；Upper end is touched
The thickness of disk (20) is 0.5～2mm, and the contact area with lower end tactile disk (21) is 2～12mm2, generally circular in shape or oval
Or rectangle or rhombus or trapezoidal；The thickness of described lower end tactile disk (21) is identical with upper end tactile disk (20) with shape；Pin hole (22) is
Cylindrical hole, a diameter of 1～2mm, highly it is less than the thickness of upper end tactile disk (20), number is 1～3；Described contact pilotage (23) is round
Cylinder, diameter is slightly less than pin hole (22), highly identical with pin hole (22) or slightly above pin hole, number and position distribution and pin hole phase
With.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610854129.8A CN106344044A (en) | 2016-09-27 | 2016-09-27 | Partially separable smart capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610854129.8A CN106344044A (en) | 2016-09-27 | 2016-09-27 | Partially separable smart capsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106344044A true CN106344044A (en) | 2017-01-25 |
Family
ID=57858566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610854129.8A Pending CN106344044A (en) | 2016-09-27 | 2016-09-27 | Partially separable smart capsule |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106344044A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240108241A1 (en) * | 2020-05-12 | 2024-04-04 | Massachusetts Institute Of Technology | Gastroretentive articles for alcohol sensing |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005062717A2 (en) * | 2003-12-31 | 2005-07-14 | Given Imaging Ltd. | In-vivo sensing device with detachable part |
| CN102631183A (en) * | 2012-05-03 | 2012-08-15 | 重庆大学 | Novel intellectual detection system of gastric fluid occult blood |
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2016
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| WO2005062717A2 (en) * | 2003-12-31 | 2005-07-14 | Given Imaging Ltd. | In-vivo sensing device with detachable part |
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