Broad-spectrum fungicide
The invention belongs to the hygiene field, relate in particular to a kind of broad-spectrum fungicide.
In existing numerous external sterilizing biocide preparation, a lot of effectively bactericide are arranged, fruit is fine, but it is colourless that they all do not possess simultaneously, nothing is smelt, tasteless, do not pollute subject, good stability, the working concentration of its preparation is nontoxic, not chafe and mucous membrane, there are not advantages such as irritated effect, as, all commercially available phenols biocide preparations, pair cell is killed very capable, can be all toxic, and strong peculiar smell arranged, it is also very strong that all chloride biocide preparations, pair cell are killed ability, but have the excitant of the unacceptable poisonous chlorine of people to smell flavor, metronidazole, bactericidal actions such as hibitane are also all good, unfortunately extremely strong bitter taste is all arranged,, very dark color is arranged though sterilizing powers such as P.V iodine are stronger, and pollute subject when using, these drawbacks limit they being extensive use of in people's sphere of life.
The object of the present invention is to provide a kind of broad-spectrum fungicide, it can kill Gram-positive Tong, gram-negative bacteria, multiple virus, brood cell and fungi etc. widely, and have simultaneously colourless, do not have smell, tasteless, do not pollute subject, good stability, its preparation working concentration is nontoxic, do not stimulate characteristics such as human body skin, mucous membrane, the irritated effect of nothing, to overcome the defective of present commercially available biocide preparation.
The present invention adopts following technical scheme:
Broad-spectrum fungicide of the present invention is characterized in, it is by the chlorophenol phenylate
Form with in surfactant, polyalcohol, the unit alcohol 1 to 3 kind mixed preparing in distilled water, surfactant is the non-basic surface activating agent with certain antibacterial action, polyalcohol is the polyalcohol with synergistic effect, it can be polyethylene glycol, it also can be the polyalcohol that contains 2~3 carbon atoms and have 2~3 hydroxyls, unit alcohol is ethanol, content with non-basic surface activating agent of certain antibacterial action is 0.1~2%, content with polyalcohol of synergistic effect is 3~30%, the content of unit alcohol is 15~60%, the chlorophenol phenylate
Content be 0.1ppm to 5%, this broad-spectrum sterilization preparation can be used for killing grampostive bacteria, gram-negative bacteria, brood cell, fungi and multiple virus widely, the preparation of this broad-spectrum sterilization preparation institute working concentration is nontoxic, can be directly used in air-atomizing and imitate poison, the infiltration of body surface, tableware and various body surfaces is sterilized or is embrocated sterilization.
The antibacterial tests result of the present invention in the research process for preparation shows, the mutual synergy of each component is apparent in view in the said preparation, the antibiotic minimal effective concentration (according to the bacterial classification of the Ministry of Public Health to the antibacterial tests appointment) of the former powder of chlorophenol phenylate (commodity are called Wei Jieling--100) is 1PPM (seeing Appendix), the antibiotic minimal effective concentration of broad-spectrum fungicide of the present invention is that 0.5PPM is (with the cubage of chlorophenol phenylate in preparation to identical appointment bacterial classification, see Appendix), some material of proof can suppress the antibacterial ability of chlorophenol phenylate in the experiment, and other materials can be strengthened the antibacterial ability of chlorophenol phenylate, have the non-basic surface activating agent and the polyalcohol with synergistic effect of certain antibacterial action as used in the present invention.
Following mask body narration embodiment:
Embodiment one:
Get 0.1 gram chlorobenzene phenolic ether biocide agent (content 〉=99%), join in the mixed solution of 5 gram propane diols and 38 gram ethanol, add 0.5 gram nonoxinol then, at room temperature stir after molten Jie mixes, add distilled water to 100 again and restrain, can use.
Embodiment two:
Get 0.1 gram chlorophenol phenylate bactericide (content 〉=99%), join in the mixed solution of 5 gram propane diols and 38 gram ethanol, at room temperature stir after molten Jie mixes, add distilled water to 100 again and restrain, can use.
Get above-mentioned preparation respectively, " defend clean clever high effect disinfectants " with trade name and carry out antibacterial tests by Ministry of Public Health's disinfectant for external use test specification, its result is as follows: bacterial classification embodiment one embodiment two
MIC (PPM) MIC (PPM) Escherichia coli (8099) 0.5 0.5 bacillus subtilis black variety bud cells
(ATCC 9372) 2.0 2.0 diplococcuses (29106) 3.0 3.0
HBsAg 250.0 250.0 staphylococcus aureuses (ATCC 6538) 0.1 0.1
(detailed results is seen Appendix)
This preparation is respectively applied for the air-atomizing sterilization, sterilization is cleaned on surface such as furniture, apparatus, the infiltration sterilization of body surface, hand, the shower sterilization, and the spraying of outer suit, clean sterilization after, show through assay, be sterilized object and need only contact 2~5 minutes with this preparation, promptly reach the purpose of sterilizing.
Facts have proved, broad spectrum activity antibiotic preparation of the present invention, its prescription rationally, and creative and novelty, have practicality simultaneously, overcome the problem that existing biocide preparation exists, can widely be used in people's the sphere of life, be a kind of have high safety and biocide preparation efficiently, reach design purpose.