CN106359604A - Infant formula milk powder for improving health of intestinal tract and preparation method thereof - Google Patents
Infant formula milk powder for improving health of intestinal tract and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
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Abstract
The invention provides infant formula milk powder for improving health of intestinal tracts, which is prepared with raw milk as a main raw material with addition of whey protein powder being rich in MFGM and other materials. By means of the novel whey protein powder being rich in MFGM as the raw material, contents of bio-active substances having special functional components, such as MFGM protein, lactoferrin, phospholipid, gangliosides, sphingomyelin, sialic acid and the like, are increased by regulation of the formula, so that the milk powder can promote colonization of probiotics in intestinal flora of infants and improves the content of immune factors in intestinal tracts and reduces intestinal disease incidence. The formula is suitable for researching on formula milk powder for infants and follow-up infants.
Description
Technical field
The present invention relates to food engineering field, specifically, be related to a kind of infant formula promoting intestinal health and
Its preparation method.
Background technology
Breast milk is the optimal natural food of baby, and in breast milk, abundant nutrient substance provides for the growth promoter of infant
Energy and nutritional need.But for some because itself or extrinsic factor lead to breast milk deficiency or cannot implement breast feeding
Person, baby formula milk powder becomes its infant physical growth initial stage main breast milk supplement or breast milk succedaneum.Therefore, infant is joined
The exploitation of square milk powder, all with breast milk as standard, makes it in battalion by adjusting the Nomenclature Composition and Structure of Complexes of each nutrient on the basis of Lac Bovis seu Bubali
Support and functionally all close to breast milk.Recently as the further investigation discovery to breast milk composition, trace active composition butter oil
Ball film (mfgm) is far above in milk in the content in breast milk, and distinctive bioactive lipid and unique film egg in its component
Contribute to the several functions such as the raising of infant cognitive competence, intestinal growth, immune system maturation in vain so as to become baby formula
The emphasis of milk powder research and development.
Research currently, with respect to mfgm and application focus mostly on greatly Component seperation, identification and by zoopery to its work(
Energy Property Verification aspect, and its applied research in clinic is less.Multiple hypothesis are still suffered from for its nutritive value, lacks true
Real reliable data supporting.My raw-food material company limited of Denmark dominates a clinical trial follow-up investigation of enforcement 499
The healthy babies at name 6-11 monthly age, after its medicated porridge powder supplements the egg albumen powder rich in mfgm, the growth promoter of 6 monthly ages above baby
Index and matched group no significant difference, but infantile diarrhea prevalence significantly reduces；Billeaud et al. adopts non-pessimum to assume examination
Method of testing is evaluated to the safety of the babies ' formula milk powder rich in mfgm and toleration, and result shows that edible two kinds are rich in mfgm
The body weight increase of formula milk baby is poor unlike matched group, and baby is respectively provided with good toleration to both formula milks.
Existing for the lactalbumin powder rich in mfgm in the application in clinic, medicated porridge in the diatery supplement of baby after 6 monthly ages
Middle its clinical efficacy evaluation of egg albumen powder added rich in mfgm is affected larger by many factors such as other foods.And join in baby
Used in square milk powder, safety and the toleration of product has only been investigated in clinical research, for wherein critical function component in baby
The internal concrete effect playing there is no to be studied further.
It is raw material that the present invention passes through from the new lactalbumin powder rich in mfgm, has spy by formula adjustment lifting
The bioactive substance (mfgm albumen, lactoferrin, phospholipid, ganglioside, sphingomyelin, sialic acid) of different functional component
Content, reach promote baby intestinal flora in probiotic bacteria field planting, improve intestinal in immune factor content and reduce intestinal
The purpose of disease incident, this formula is applied to baby and the exploitation of larger infant formula.
Content of the invention
The purpose of the present invention is by from the lactalbumin powder rich in milk fat ball film (mfgm), improving formulated infant milk
The content of total mfgm albumen, lactoferrin, phospholipid, ganglioside, sphingomyelin, sialic acid etc. in powder, reaches promotion baby
The normal field planting of youngster's intestinal microbial population, improves the content of immune factor and the purpose preventing intestinal tract disease generation, this formula in intestinal
It is applied to baby and the exploitation of larger infant formula.
In order to realize the object of the invention, the milk power for infant and young children of present invention design, with raw milk as primary raw material, passes through
Add rich in the lactalbumin powder of mfgm, common lactalbumin powder, fats, Lactose, oligosaccharides, mineral, vitamin and
After some optional nutritional labelings (choline, inositol, taurine, carnitine etc.) carry out dispensing standardization, the infant formula milk that modulates
Powder has the effect promoting baby intestinal health.
The present invention provides a kind of infant formula promoting intestinal health, and described infant formula is to be with raw milk
Primary raw material, is formed by adding the lactalbumin powder being rich in mfgm and other dispensing modulation；Wherein every 100 grams of described babies join
In square milk powder, the content of functional active components is as follows: total mfgm albumen 0.146-0.438g, phosphatidase 0 .175-0.525g, nerve sheath
Phosphatidase 0 .04-0.12g, sialic acid 0.05-0.18g, lactoferrin 0.02-0.06g, immunoglobulin igg0.1-0.3g, curdling
Collection plain 0.025-0.075g, ganglioside 0.005-0.015g, muc1 albumen 0.035-0.105g.(table 1)
Table 1 has the content of functional active components in the babies ' formula milk powder promoting intestinal health
Preferably, in every 100 grams of described infant formulas, the content of functional active components is as follows: total mfgm albumen
0.251g, phosphatidase 0 .301g, sphingomyelin 0.0688g, sialic acid 0.171g, lactoferrin 0.0344g, immunoglobulin
Igg 0.172g, lactadherin 0.043g, ganglioside 0.0086g, muc1 albumen 0.0602g.
Described infant formula can be prepared using wet method processing technology: be rich in adding in pre-sterilized raw milk
The lactalbumin powder of mfgm and other dispensing, are sterilized after homogenizing, and then concentrated, spray drying is obtained described infant formula
Milk powder.
Addition for the lactalbumin powder rich in mfgm in the formula powder of different phase or different body constitution baby exploitation
Need to be adjusted according to practical situation, add the described breast rich in mfgm in raw milk by the scope of solid-liquid ratio 1-3:80kg/l
Albumin powder.
It is rich in the lactalbumin powder of mfgm used in the present invention, can prepare according to following technique: raw milk passes through
Pasteurize (72 DEG C -85 DEG C, 5-15s) removes cheese or casein afterwards, obtains whey；The casein removing in whey is micro-
Residue in grain and fat and milk surum, then through (60 DEG C -75 DEG C, 3-5min) dilute creams removing in milk surum of Overheating Treatment, institute
Obtain milk surum rewinding cold preservation at 4 DEG C -6 DEG C.Make milk surum rewinding temperature rise to 50 DEG C -55 DEG C before filtration, (cut using special filter membrane
Stay molecular weight 1kda-100kda) filtered, the filtrate obtaining after heavy filtration carry out again heat treatment (60 DEG C -75 DEG C, 3-
5min), then it is spray-dried and obtain final product.The lactalbumin powder being obtained using above-mentioned technique compared with general proteins powder, the main distinction
Be wherein functional active components (mfgm albumen, phospholipid, sphingomyelin, sialic acid, lactoferrin, immunoglobulin igg,
Lactadherin, ganglioside and muc1 albumen) content relative improve, and this 9 kinds of functions are lived in common lactalbumin powder
Property is in trace or minor levels.
Main nutrient composition relative mass percentage composition in the lactalbumin powder rich in mfgm being obtained using above-mentioned technique
As follows: lactalbumin 70%-75%, total mfgm albumen 3%-7%, phosphatidase 5 %-9%, sphingomyelin 0.5%-3%, saliva
Sour 1%-3%, lactoferrin 0.5%-2%, immunoglobulin igg 2%-6%, lactadherin 0.5%-2%, ganglioside
Fat 0.1%-0.5%, muc1 albumen 1%-3%.
Other dispensings include alpha-lactoalbumin containing common lactalbumin powder, lipid, fatty acid, Lactose, oligosaccharides, many
Polysaccharide class, mineral, vitamin, choline, peptides, inositol, taurine, phylloxanthin, carnitine etc..
In a specific embodiment of the present invention, add table 2 in described raw milk by solid-liquid ratio 1:46.5kg/l
The described lactalbumin powder rich in mfgm.Other principal ingredients include the Lactose, mixed vegetable oil containing opo Structure grease, general
Logical lactalbumin powder (containing alpha lactalbumin), oligomeric galactose (gos), oligofructose (fos), polyfructosan
(polyfructose), docosahexenoic acid (dha, source split kettle algae), arachidonic acid (ara), taurine, mineral,
Vitamin, nucleotide, l- carnitine tartrate, phosphopeptide caseinate (cpp), phylloxanthin etc., wherein main Macronutrient contains
Amount is shown in Table 3.
Table 2 is from Lac Bovis seu Bubali rich in functional active components relative amount in mfgm lactalbumin powder
Table 3 has main magnanimity nutrient composition content table in the infant formula promoting intestinal health
Contain in every 100 grams of described infant formulas: total mfgm albumen 0.251g, phosphatidase 0 .301g, sphingomyelin
0.0688g, sialic acid 0.171g, lactoferrin 0.0344g, immunoglobulin igg 0.172g, lactadherin 0.043g, nerve
Section glycosides fat 0.0086g, muc1 albumen 0.0602g, alpha-lactoalbumin containing common lactalbumin powder 3.7g, Lactose 46.2g, contains
The mixed vegetable oil 19.3g of opo Structure grease, oligomeric galactose 0.89g, oligofructose 0.1g, polyfructosan 0.07g, 20
Two carbon acid 0.045g, arachidonic acid 0.065g, taurine 0.038g, mineral 1.32g, vitamin 0.079g, nucleoside
Sour 0.025g, l- carnitine tartrate 0.007g, phosphopeptide caseinate 0.045g, phylloxanthin 0.00007g.
The infant formula of the promotion intestinal health of the present invention, can be prepared as follows: adopt wet method processing technology
(Fig. 1), using raw milk as raw milk, only carry out pre-sterilizing after breast, be rich in mfgm to adding in pre-sterilized raw milk
Lactalbumin powder and other dispensing, sterilized after homogenizing, then concentrated, be spray-dried, obtain final product.
Main technologic parameters are: pre-sterilizing (85 DEG C -88 DEG C, 30s)；Homogenizing 15mpa；Sterilization (93 DEG C -95 DEG C, 15s)；Spray
Mist is dried (150 DEG C -160 DEG C of inlet temperature, 85 DEG C -90 DEG C of leaving air temp).
The detection of product nutritive index, physical and chemical index, microbiological indicator and organoleptic indicator is in strict accordance with food safety country
The detection project that standard infant formulation (gb-10765-2010) is specified and the method for inspection are carried out.
In the another embodiment of the present invention, using high throughput sequencing technologies to 16s rdna in infant faeces
Gene carries out sequencing analysis, investigates and adds the shadow that the formula milk of the lactalbumin powder rich in mfgm is constituted to baby intestinal flora
Ring, and combine baby's defecation situation, in intestinal tract disease incidence rate and feces immune factor content, from macroscopic perspective to being rich in
The infant formula of mfgm gives data and supports to the facilitation of intestinal health.
What the present invention provided has the prescription emulsifiable powder promoting baby intestinal health, by adding the lactalbumin rich in mfgm
Powder, improve formula in have specific function effect total mfgm albumen, lactoferrin, igg, lactadherin, muc1/mucin1,
The content of 9 kinds of functional active components such as phospholipid, ganglioside, sphingomyelin and sialic acid so as to as far as possible close to breast milk,
So that the baby intestinal flora eating this formula constitutes and prebiotic bacterial content is close to breast feeding babies；Lift feces simultaneously
The content of middle siga is to strengthen intestinal immunity；In conjunction with the baby intestinal disease eating this formula, a situation arises, result table
Bright, this product has facilitation it is adaptable to the exploitation of baby and larger infant formula to baby intestinal health, particularly suitable
In 1 section of design of babies ' formula milk powder.
Brief description
Fig. 1 has the processing process figure of the infant formula promoting intestinal health for the present invention.
Fig. 2 is that in present pre-ferred embodiments, two kinds of formula milk group babies are tied with breast milk group infant faeces COMPARISON OF CHARACTERS
Really.Wherein, 1 group of milk powder is common infant formula nursing group (ff1), and 2 groups of milk powder is the infant formula adding rich in mfgm
Milk powder group (ff2).
Specific embodiment
Following examples are used for the present invention is described, but are not limited to the scope of the present invention.If not specializing, embodiment
All according to conventional laboratory conditions, such as sambrook equimolecular Cloning: A Laboratory Manual (sambrook j＆russell dw,
Molecular cloning:a laboratory manual, 2001), or the condition according to manufacturer's description suggestion.
It is rich in the relative mass percentage of 9 kinds of functional active components in the lactalbumin powder of mfgm used in following examples
Content is shown in Table 2.
1 section of babies ' formula milk powder of normal control group is purchased from Sanyuan Food Co., Ltd., Beijing, and trade name " like by golden clothes
Intelligence is good for babies ' formula milk powder ".
Embodiment is applied to the babies ' formula milk powder with promotion intestinal health of 0-6 month infant
1st, it is suitable for the design with the formula milk promoting baby intestinal health at 0-6 monthly age
With raw milk as primary raw material, be especially added with the lactalbumin powder rich in mfgm, other principal ingredients include Lactose,
Mixed vegetable oil containing opo Structure grease, common lactalbumin powder (containing alpha lactalbumin), oligomeric galactose (gos), oligomeric
Fructose (fos), polyfructosan (polyfructose), docosahexenoic acid (dha, kettle algae is split in source), arachidonic acid
(ara), taurine, mineral, vitamin, nucleotide, l- carnitine tartrate, phosphopeptide caseinate (cpp), phylloxanthin etc.,
Wherein main Macronutrient content is shown in Table 3.Table 4 show in 9 functional active components in breast milk, in inventive formulation and general
Comparision contents in logical matched group, as shown in Table 4, by adding in the formula being rich in after the lactalbumin powder of mfgm, 9 kinds of functions
Active component content is higher than comparison formula milk group, and it is relatively close to the content of these functional active components in breast milk group.
Table 4 has functional active components content in the infant formula promoting intestinal health
Contain in every 100 grams of described new prescription emulsifiable powders: total mfgm albumen 0.251g, phosphatidase 0 .301g, sphingomyelin
0.0688g, sialic acid 0.171g, lactoferrin 0.0344g, immunoglobulin igg 0.172g, lactadherin 0.043g, nerve
Section glycosides fat 0.0086g, muc1 albumen 0.0602g, alpha-lactoalbumin containing common lactalbumin powder 3.7g, Lactose 46.2g, contains
The mixed vegetable oil 19.3g of opo Structure grease, oligomeric galactose 0.89g, oligofructose 0.1g, polyfructosan 0.07g, 20
Two carbon acid 0.045g, arachidonic acid 0.065g, taurine 0.038g, mineral 1.32g, vitamin 0.079g, nucleoside
Sour 0.025g, l- carnitine tartrate 0.007g, phosphopeptide caseinate 0.045g, phylloxanthin 0.00007g.
Designed new formula infant milk powder adopts wet method processing technology, and Fig. 1 is shown in technological process.Using raw milk as raw material
Breast, carries out pre-sterilizing after breast only, adds, in pre-sterilized raw milk 46.5l, the lactalbumin powder that 1kg is rich in mfgm, and
Add other dispensings, sterilized after homogenizing, then concentrated, spray drying, obtain final product.
Main technologic parameters are: pre-sterilizing (85 DEG C -88 DEG C, 30s)；Homogenizing 15mpa；Sterilization (93 DEG C -95 DEG C, 15s)；Spray
Mist is dried (150 DEG C -160 DEG C of inlet temperature, 85 DEG C -90 DEG C of leaving air temp).
2nd, product nutritional quality and safety detection
There is the infant formula promoting intestinal health according to designing after adding rich in the lactalbumin powder of mfgm
The product that obtains after pilot scale of formula entrust Beijing Haidian Quality Supervision and Examination Institute according to food safety country
After the requirement of standard infant formulation (gb-10765-2010) is checked item by item, product indices are up to state standards,
Product is qualified.
3rd, add the clinical efficacy evaluation to baby intestinal health benefit for the infant formula being rich in mfgm
3.1 intestinal microbial populations constitute the impact with Changing Pattern
Breast feeding group (bf), common infant formula nursing group (ff1) and the interpolation infant formula milk rich in mfgm
It is as shown in table 5 that the baby of powder group (ff2) intestinal microbial population from birth to 6 monthly ages constitutes Changing Pattern.As can be seen from Table 5, exist
In door level, three groups of baby intestinal flora ranking dominant microfloras of first three are bacteroid bacteroidetes, sclerine bacterium
Firmicutes and mycetozoan proteobacteria, and with three kinds of bacterium relative abundance variation tendencies in three groups of the change at monthly age
Unanimously, being bacteroidetes is in the trend gradually rising, and proteobacteria assumes the trend being gradually lowered, but
The relative of three kinds of dominant bacterias of person in three groups of baby intestinals under different time points is compared by cruskal-wallis rank test method
Abundance (table 6), result shows no significant difference (p ＞ 0.05).
The relative abundance of three groups of baby intestinal dominant microfloras in 5 levels of table
With breast milk group as standard, by descending order, ranking is carried out in 85% flora to section's level of relative abundance,
Result is as shown in table 6 first row.To the relative abundance of this 9 kinds of bacterium in two group of formula milk powder group baby intestinal floras respectively with breast milk
Group baby is compared analysis, and obtained p value is listed in table 7.As can be seen from Table 7, baby intestinal flora in formula milk ff1 group
Difference flora and breast milk group baby between assumes unstable Changing Pattern with the growth at monthly age, by just connatae 2 kinds of differences
Different flora, increases as 5 species diversity bacterium, and sports zero difference flora during to 6 monthly age during to 3 monthly age；But formula milk ff2 group
Although in be born 1 monthly age when compare with breast milk group and have 3 species diversity floras, the increase with the monthly age assumes becoming of steady decrease
Gesture, the difference flora to both during 6 monthly age between is only a kind, thus infers the edible formula milk baby intestinal bacterium rich in mfgm
Group is gradually decreased with the difference of breast milk group with relative abundance with the flora composition that increases at monthly age, and flora is constituted with breast milk group gradually
Close.
The cruskal-wallis sum of ranks of three groups of baby intestinal flora relative abundances under different time points in 6 levels of table
Inspection p value
Two kinds of formula milk group baby p values with breast milk group baby intestinal flora comparing difference respectively in table 7 section's level
Note: statistical method is (mann-whitney) u-test method, the wherein use overstriking italic of p ＜ 0.05 indicates.
The detection of immune factor in 3.2 feces
In order to investigate the situation of three groups of baby intestinal local immunity power, analyze the content of siga in feces, result such as table 8
Shown, as can be seen from Table 8, in three groups of baby intestinals, the content of siga all presents and first increases the trend reducing afterwards, but no notable
Difference (p ＞ 0.05), and the content comparing siga in baby intestinal under each monthly age finds that the three groups of babies selecting in the present invention go out
In green tire excrement, the content of siga content in ff2 group is substantially less than breast feeding group and ff1 group, but after the nursing of 15 days,
Content in ff2 group is close with ff1 group, but is less than breast milk group, but reaches in three groups of baby intestinals during 1 monthly age siga content no
Significant difference.This shows that the formula milk adding rich in mfgm contributes to stimulating baby intestinal mucosal secretions immune factor siga,
Thus improving baby intestinal immunity.
Immune factor siga comparision contents (μ g/ml, x ± s) in baby intestinal under table 8 Different Month
Note: same row difference lower case a and b represents there is significant difference in the level of α=0.05 between different groups
3.3 baby's defecation situations and the incidence rate of intestinal tract disease
Defecation character is that the important clinical evaluating baby formula milk powder comfort level refers to one of disease.Specific nutrition in breast milk
The Nomenclature Composition and Structure of Complexes determines the feature of its absorption easy to digest, and numerous studies show breast feeding babies fecal character compared with formula milk
Feeding infant feces are soft.Result of the present invention is as shown in Fig. 2 figure it is seen that from 1-6 monthly age breast feeding babies feces
Character gradates as half form by loose stool, and formula fed infant fecal character be gradually converted into based on half form with
Based on shaping.But compare two group of formula milk powder groups and find that during ff2 group baby 1-3 monthly age, loose stool and half form relative scale are higher than
Ff1 group, to two group of formula fed infant during 6 monthly age all based on shaping feces.This result shows, the baby of ff2 group
Fecal character is more releived by the process that loose stool and half form are gradually converted into shaping compared with ff1 group baby, shows that edible interpolation is rich in
The formula milk of mfgm lactalbumin is to the baby that baby intestinal comfort level is higher than food sanitation standard formula powder.
Intestinal tract disease incidence rate is to investigate an important indicator of baby intestinal health, and the present invention utilizes Chi-square method ratio
Compared with the difference of three groups of baby intestinal disease incidences, as shown in Table 9, two kinds of formula fed infant intestinal tract disease sickness rate
With breast feeding babies under 1-6 monthly age each time point equal no significant differences.After the lactalbumin rich in mfgm is added in this explanation
Formula milk and common standard formula milk breast feeding group baby is all not significantly higher than to the incidence rate of baby intestinal disease
Youngster, is conducive to the healthy development of baby intestinal.
9 three groups of baby intestinal disease incidents of table compare
Addition for the lactalbumin powder rich in mfgm in the formula powder of different phase or different body constitution baby exploitation
Need to be adjusted according to practical situation, add the described breast rich in mfgm in raw milk by the scope of solid-liquid ratio 1-3:80kg/l
Albumin powder, prepared formula milk has functions that similar promotion baby intestinal health.
Although, above the present invention is described in detail with a general description of the specific embodiments,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to the scope of protection of present invention.
Claims (10)
1. a kind of infant formula promoting intestinal health is it is characterised in that described infant formula is to be with raw milk
Primary raw material, is formed by adding the lactalbumin powder being rich in mfgm and other dispensing modulation；
In wherein every 100 grams of described infant formulas, the content of functional active components is as follows: total mfgm albumen 0.146-
0.438g, phosphatidase 0 .175-0.525g, sphingomyelin 0.04-0.12g, sialic acid 0.05-0.18g, lactoferrin 0.02-
0.06g, immunoglobulin igg 0.1-0.3g, lactadherin 0.025-0.075g, ganglioside 0.005-0.015g, muc1
Albumen 0.035-0.105g.
2. infant formula according to claim 1 is it is characterised in that work(in every 100 grams of described infant formulas
The content of energy active component is as follows: total mfgm albumen 0.251g, phosphatidase 0 .301g, sphingomyelin 0.0688g, sialic acid
0.171g, lactoferrin 0.0344g, immunoglobulin igg 0.172g, lactadherin 0.043g, ganglioside 0.0086g,
Muc1 albumen 0.0602g.
3. infant formula according to claim 1 and 2 it is characterised in that prepared described using wet method processing technology
Infant formula: to the lactalbumin powder adding in pre-sterilized raw milk rich in mfgm and other dispensing, after homogenizing
Sterilized, then concentrated, spray drying is obtained described infant formula.
4. the infant formula according to any one of claim 1-3 it is characterised in that press solid-liquid ratio 1-3:80kg/l to
Add the described lactalbumin powder rich in mfgm in described raw milk.
5. the infant formula according to any one of claim 1-4 is it is characterised in that the described milk surum egg rich in mfgm
In white lead, the relative mass percentage composition of functional active components is as follows: total mfgm albumen 3%-7%, phosphatidase 5 %-9%, nerve sheath
Phosphatidase 0 .5%-3%, sialic acid 1%-3%, lactoferrin 0.5%-2%, immunoglobulin igg 2%-6%, lactadherin
0.5%-2%, ganglioside 0.1%-0.5%, muc1 albumen 1%-3%.
6. the infant formula according to any one of claim 1-5 is it is characterised in that other dispensing is included containing alpha-whey
The common lactalbumin powder of albumen, lipid, fatty acid, Lactose, oligosaccharides, polysaccharide, mineral, vitamin, choline, peptide
Class, inositol, taurine, phylloxanthin, carnitine.
7. the infant formula according to any one of claim 1-6 is it is characterised in that every 100 grams of described infant formulas
In milk powder, main magnanimity nutrient composition content is as follows: protein 11.6g, fatty 27g, carbohydrate 56.4,1, and 3- bis- Oleic acid-
2- palmitic acid three fat 4.2g；Wherein, 2 Palmic acids account for the 40% of total palmitic acid content；
The energy of every 100 grams of described infant formulas is 2162kj.
8. the infant formula according to any one of claim 1-7 is it is characterised in that every 100 grams of described infant formulas
Contain in milk powder: total mfgm albumen 0.251g, phosphatidase 0 .301g, sphingomyelin 0.0688g, sialic acid 0.171g, newborn ferrum egg
White 0.0344g, immunoglobulin igg 0.172g, lactadherin 0.043g, ganglioside 0.0086g, muc1 albumen
0.0602g, alpha-lactoalbumin containing common lactalbumin powder 3.7g, Lactose 46.2g, the mixed plant containing opo Structure grease
Oily 19.3g, oligomeric galactose 0.89g, oligofructose 0.1, polyfructosan 0.07g, docosahexenoic acid 0.045g, Semen arachidis hypogaeae four
Olefin(e) acid 0.065g, taurine 0.038g, mineral 1.32g, vitamin 0.079g, nucleotide 0.025g, l- carnitine tartrate
0.007g, phosphopeptide caseinate 0.045g, phylloxanthin 0.00007g.
9. the preparation method of infant formula described in any one of claim 1-8 is it is characterised in that adopt wet processing work
Skill, using raw milk as raw milk, carries out pre-sterilizing after breast only, to the breast adding in pre-sterilized raw milk rich in mfgm
Albumin powder and other dispensing, are sterilized after homogenizing, and then concentrated, spray drying obtains final product.
10. method according to claim 9 is it is characterised in that 85 DEG C -88 DEG C of pre-sterilizing condition, 30s；Processing condition
15mpa；93 DEG C -95 DEG C of sterilization conditions, 15s；Spray drying condition: 150 DEG C -160 DEG C of inlet temperature, 85 DEG C -90 of leaving air temp
℃.
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN112042750A (en) * | 2020-09-09 | 2020-12-08 | 北京三元食品股份有限公司 | Infant formula milk powder rich in milk fat globule membrane protein, phospholipid and oligosaccharide and preparation method thereof |
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| CN106857855A (en) * | 2016-12-19 | 2017-06-20 | 北京三元食品股份有限公司 | A kind of infant formula rich in milk fat ball film and structured lipid OPO and preparation method thereof |
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| EP4164414A4 (en) * | 2020-06-15 | 2024-07-10 | Building Block Nutritionals Llc | Nutritional formula |
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| WO2022052794A1 (en) * | 2020-09-09 | 2022-03-17 | 北京三元食品股份有限公司 | Infant formula milk powder rich in milk fat globule membrane protein, phospholipid and oligosaccharide, and preparation method therefor |
| AU2021340764B2 (en) * | 2020-09-09 | 2022-12-08 | Beijing Sanyuan Foods Co., Ltd. | Infant formula milk powder rich in milk fat globule membrane protein, phospholipid and oligosaccharide, and preparation method therefor |
| WO2022143788A1 (en) * | 2020-12-29 | 2022-07-07 | 丰益(上海)生物技术研发中心有限公司 | Composition for improving digestion of lipid contained in food, and use thereof |
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