CN106353221A - Blood stagnation state detection equipment and blood stagnation state detection method - Google Patents

Blood stagnation state detection equipment and blood stagnation state detection method Download PDF

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Publication number
CN106353221A
CN106353221A CN201610737062.XA CN201610737062A CN106353221A CN 106353221 A CN106353221 A CN 106353221A CN 201610737062 A CN201610737062 A CN 201610737062A CN 106353221 A CN106353221 A CN 106353221A
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CN
China
Prior art keywords
rotating shaft
nand gate
inductance coil
blood
rotating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610737062.XA
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Chinese (zh)
Inventor
李玉峰
蒋皆恢
时浩
王旭智
王瑞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anhui National Science Biotechnology Co., Ltd.
Original Assignee
李玉峰
王旭智
王瑞
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 李玉峰, 王旭智, 王瑞 filed Critical 李玉峰
Priority to CN201610737062.XA priority Critical patent/CN106353221A/en
Publication of CN106353221A publication Critical patent/CN106353221A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/14Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane

Abstract

The invention discloses blood stagnation state detection equipment. A system comprises a detection unit and a rotary unit below the detection unit. Blood viscosity is detected through a differential frequency detection method. The blood stagnation state detection equipment has advantages that the system is simple, stable and reliable; due to measurement of basic oscillation frequency, calibration is facilitated; by adoption of a totally digital circuit, requirements on a power source are low; the equipment is low in manufacturing cost and stable in performance.

Description

Blood stagnation condition detecting device and method
Technical field
The present invention relates to blood testing equipment field.
Background technology
The viscous situation of blood clotting in Blood coagulation test, can be indicated by the deflection of angle, the precision of angle detection is straight Connect the accuracy affecting Blood coagulation parameters.Moreover, the detection in other fields minute angle also has a wide range of applications.Angle The detection method of degree is varied, such as just can reach higher accuracy of detection by laser detection, but laser detection cost is relatively Height, receives limitation in some costs are than more sensitive product.
Content of the invention
The technical problem to be solved be realize a kind of low cost, stable performance, be easy to calibrate blood blood clotting Viscosity detecting system.
To achieve these goals, the technical solution used in the present invention is: a kind of blood stagnation condition detecting device, system Rotary unit including detector unit and below detector unit;
Described detector unit is provided with horizontal fixed inductance coil t1 and inductance coil t2, the top of two inductance coils or under Side is vacantly provided with fan-shaped metallic plate, and the circle centre position of described sector metallic plate is fixed in the rotating shaft being vertically arranged, described rotating shaft bottom End is fixed with contact head, and described rotating shaft is fixed on upper support seat by bearing, is provided with torsion spring between described rotating shaft and bearing, when Rotating shaft do not stress state when, described sector metallic plate identical with the overlapping area of inductance coil t1 and inductance coil t2 respectively, institute State two inductance coils to be connected with oscillating circuit, by logical block energy supply, described logical block includes gathering described oscillating circuit The enumerator of oscillating circuit frequency, the square-wave generator exporting square wave to oscillating circuit and the Control on Communication list communicating with mcu Unit;
Described rotary unit is fixed on elevating mechanism, and the rotating seat top center of described rotary unit is provided with and rotates Seat, rotating shaft coaxial blood vessel, the taper type of described rotating seat inner hollow or the structure of cylinder, described rotating seat peripheral hardware Dynamic gear, described power gear is engaged with the driving gear on power motor output shaft, described rotating seat inner hollow area Domain is provided with heated beam, is provided with heater strip and temperature sensor, described heating column top and blood vessel contacts in described heated beam.
The one of input of NAND gate g1 of described oscillating circuit connects the outfan of square-wave generator, square-wave generator Outfan connect with two inputs of NAND gate g3 simultaneously, another input of described NAND gate g1 connects through electric capacity c1 Ground, described NAND gate g1 outfan connects inductance coil t1 one end, and the described inductance coil t1 other end connects electric capacity c1, described with The outfan of not gate g3 connects the one of input of NAND gate g2, and another input of described NAND gate g2 connects through electric capacity c2 Ground, described be connected inductance coil t2 one end with NAND gate g2 outfan, described inductance coil t2 other end connection electric capacity c2, described Counter input connects the outfan of NAND gate g4, and an input of described NAND gate g4 connects NAND gate g1 through resistance r1 Outfan, another input of described NAND gate g4 connects NAND gate g2 outfan through resistance r2.
Described rotating seat top center is provided with the putting hole placing blood vessel, and described putting hole medial wall is provided with keyway, Described blood vessel lateral wall is provided with the slotting tool with keyway cooperation, is provided with draw-in groove above the slotting tool of described blood vessel lateral wall, Described rotating seat is provided with the alligator clamp clamping described draw-in groove.
Described blood vessel are transparent glass vessels, and described blood vessel are provided with graduated scale.
Described inductance coil t1 and inductance coil t2 is circular ring structure, and the area of two inductance coils is identical, adjacent not to be weighed The folded identical height and position being fixed on upper support seat, described inductance coil t1 and inductance coil t2 circle center line connecting are not stressed with rotating shaft Fan-shaped metallic plate axis during state is vertical.
Described rotating shaft is externally provided with least one support set, and described support set is fixed on upper support seat by connecting rod.
Described bearing is fixed on the cylindrical of upper support seat and installs intracavity, and described installation cavity bottom is provided with extends for rotating shaft Lower through-hole, described installation cavity top is provided with the upper through hole extending for calibration of axes, and described calibration of axes is coaxial with bearing and affixed, Described calibration of axes is provided with external gear, and described mcu output drive signal is to calibrating motor, the tune on described calibration motor output shaft Whole gear is engaged with external gear.
Described rotating seat is provided with rotation speed detection unit, described rotation speed detection unit output speed signal to mcu, described temperature To mcu, described mcu drives heater strip power supply unit to sensor output temperature signal, and the signal output part of described mcu connects display Device and alarm device.
Method of testing based on described blood stagnation condition detecting device it is characterised in that:
1) system start-up self-inspection;
2) drive elevating mechanism work, contact head is stretched in blood vessel;
3) rotating seat rotation, heating wire works;
4) mcu exports blood viscosity according to rotating shaft deflection angle;
5) rotating seat rotation and heater strip are closed;
6) drive elevating mechanism work, contact head is detached blood vessel.
Described step 1) in, rotating seat rotation and square-wave generator work;
If rotation speed detection unit detection rotating seat rotating speed is too fast or excessively slow, motivation of adjustment motor speed slows down or accelerates, Until rotating seat rotating speed is normal;
If it is non-zero-degree that mcu detects rotating shaft deflection angle, drive correcting motor adjustment rotating shaft relative position, until turning Axle deflection angle is zero degree;
If rotating seat rotating speed and rotating shaft deflection angle are zero degree, execute next step.
It is an advantage of the current invention that simple system and reliable and stable, due to fundamental oscillation frequency can be measured, convenient calibrate, pure Digital circuit, relatively low to power requirement, and device fabrication low cost, stable performance.
Brief description
Below content of width accompanying drawing expression every in description of the invention and the labelling of in figure are briefly described:
Fig. 1 is blood stagnation condition detecting device structure principle chart;
Fig. 2 is blood stagnation condition detecting device detection principle diagram;
Fig. 3 is blood stagnation condition detecting device block diagram;
The labelling of above-mentioned in figure is: 1, rotating shaft;2nd, contact head;3rd, heater strip;4th, rotating seat;5th, blood vessel;6th, rise Descending mechanism.
Specific embodiment
Blood stagnation condition detecting device includes detector unit and is located at the rotation list below detector unit as shown in Figure 1 Unit.
Detector unit is provided with horizontal fixed inductance coil t1 and inductance coil t2, and inductance coil t1 and inductance coil t2 is circle Ring structure, the area of two inductance coils is identical, adjacent and not overlapping, inductance coil t1 and inductance coil t2 circle center line connecting with turn Axle 1 do not stress state when fan-shaped metallic plate axis vertical.Rotating shaft 1 bottom is fixed with contact head 2, and contact head 2 is cylinder Structure, the bottom surface (end face) of contact head 2 is used for and contacting blood to be detected,
Vacantly it is provided with fan-shaped metallic plate, such as aluminium sheet, o is the axle of fan-shaped metallic plate above or below two inductance coils Point, fan-shaped metallic plate can rotate around o point, so that metallic plate covers one increase of area of two coils, another then reduces. O point position is vertically fixed rotating shaft 1, and fan-shaped metallic plate is fixed in rotating shaft 1, and fan-shaped metallic plate can rotate with rotating shaft 1, thus real Now rotate around o point.
Detector unit is fixed on upper support seat, detector unit is fixed on upper support seat and can improve stablizing of system Property, the rotation that rotary unit can be more reliable and more stable, it is to avoid equipment rocks, rotating shaft 1 is externally provided with least one support set, support set It is fixed on upper support seat by connecting rod.Rocking of rotating shaft 1 can be reduced by supporting table, improve the accuracy of detection.Inductance Coil t1 is fixed on the identical height and position of upper support seat with inductance coil t2.It is provided with torsion spring, torsion spring can between rotating shaft 1 and bearing To ensure that fan-shaped metallic plate can be placed in the middle when not stressing, when rotating shaft 1 does not stress state, fan-shaped metallic plate respectively with inductance coil T1 is identical with the overlapping area of inductance coil t2.
Rotating shaft 1 is fixed on upper support seat by bearing, and bearing is fixed on the cylindrical of upper support seat and installs intracavity, installs Chamber bottom is provided with the lower through-hole extending for rotating shaft 1, and installation cavity top is provided with the upper through hole extending for calibration of axes, calibration of axes with Bearing is coaxial and affixed, and calibration of axes is provided with external gear, and mcu output drive signal, to calibrating motor, is calibrated on motor output shaft Adjustment gear engage with external gear, by calibrate motor can adjust before guarantee detection fan-shaped metallic plate respectively with inductance coil T1 identical with the overlapping area of inductance coil t2 it is ensured that detection accuracy.
Rotary unit is fixed on 6 on elevating mechanism, and rotary unit is fixed on guarantees the work of detector unit on upper support seat Make stability, detector unit will not be subject to the disturbing of lifting unit 6 in detection, detection that can be more reliable and more stable, it is to avoid Rotating shaft 1 is rocked.
The rotating seat top center of rotary unit rotary unit is provided with the blood vessel coaxial with rotating seat, rotating shaft, rotation The seat taper type of inner hollow or the structure of cylinder, rotating seat is externally provided with power gear, and power gear is exported with power motor Driving gear engagement on axle, rotating seat interior hollow region is provided with heated beam, is provided with heater strip and temperature sensing in heated beam Device, heating column top and blood vessel contacts.
Temperature sensor output temperature signal drives heater strip 3 power supply unit, such closed loop control, energy to mcu, mcu Keep heated beam to be in temperature constant state by mcu, maintain required temperature during detection.For improving the heats of contact, Heated beam bottom surface, by spring supporting, is heated column top and is provided with the boss extending into placement in the hole, heater strip 3 and temperature sensor are solid It is scheduled in this boss, by spring effect, ensure that being fully contacted of boss and blood vessel 5, by from blood vessel 5 bottom Portion heat, ensure that blood to be detected generally in temperature constant state it is ensured that detection temperature control effect.
For convenience of blood clean vessel 5, rotating seat 4 top center is provided with the putting hole placing blood vessel 5, places in the hole Side wall is provided with keyway, and blood vessel 5 lateral wall is provided with the slotting tool with keyway cooperation, sets above the slotting tool of blood vessel 5 lateral wall There is draw-in groove, rotating seat 4 is provided with the spring clamping described draw-in groove it is ensured that the fixing reliability of blood vessel 5.Blood vessel 5 are Transparent glass vessels, blood vessel 5 are provided with graduated scale, and the convenient blood flow volume to be detected injecting in blood vessel 5 of weighing is No enough.
Rotating seat 4 is provided with rotation speed detection unit, and rotation speed detection unit output speed signal, to mcu, can pass through closed loop control, Regulation and control and control rotating seat 4 rotating speed it is ensured that detection stability.The signal output part of mcu connects display and alarm device, Display and alarm device, can give detection prompting data and show.
Two inductance coils are connected with oscillating circuit, and as shown in Figure 2,3, oscillating circuit is by logical block energy supply, logic list Unit is included the enumerator of collection oscillating circuit frequency, exports the square-wave generator of square wave to oscillating circuit and communicated with mcu Communication control unit.
Inductance coil t1 reverse gate circuit g1 and electric capacity c1 constitutes lc agitator, an inductance coil t2 reverse gate circuit g2 Constitute another agitator with electric capacity c2, the placement of two oscillator coil t1t2 as shown in Fig. 2 specifically, oscillating circuit with The one of input of not gate g1 connects the outfan of square-wave generator, the outfan of square-wave generator simultaneously with NAND gate g3 Two inputs connect, and another input of NAND gate g1 is grounded through electric capacity c1, and NAND gate g1 outfan connects inductance coil T1 one end, the inductance coil t1 other end connects electric capacity c1, and the outfan of NAND gate g3 connects the one of input of NAND gate g2, Another input of NAND gate g2 is grounded through electric capacity c2, is connected inductance coil t2 one end, inductor wire with NAND gate g2 outfan The circle t2 other end connects electric capacity c2, and counter input connects the outfan of NAND gate g4, an input warp of NAND gate g4 Resistance r1 connects NAND gate g1 outfan, and another input of NAND gate g4 connects NAND gate g2 outfan through resistance r2.
During vibration, magnetic field about is changing coil t, when the magnetic field of change runs into metallic conductor, Electric current will be produced in metallic conductor, and this electric current returns and can offset magnetic field produced by oscillator coil.From energy Angle is seen, coil is lost on fan-shaped metallic plate in the energy storage part in oscillatory process, if setting the energy of loss as de, this The energy storage carrying out coil t is e, and after covering fan-shaped metallic plate, its energy storage is e-de.Due to the reduction of energy, complete once to vibrate The required time is also reducing, so that the frequency of lc vibration increases.Namely al metallic plate rotate during, by In the change of Relative Oscillation coil area coverage, one increase d φ 1 of frequency of oscillation will be made, another one reduces d φ 2.It is poor It is worth for d φ 1+d φ 2.The size around o point deflection angle for the fan-shaped metallic plate, d φ=f (d can be calculated according to the value of d φ 1+d φ 2 φ1+dφ2).
Because inductance coil t1t2 is reciprocity, the impact to frequency of oscillation of the ripple of temperature and supply voltage is equal, Be common mode information, and after difference the value of d φ 1+d φ 2 then, common mode part will be eliminated.Read by way of difference Frequency values more precisely more stable than single-frequency detection.But, fundamental frequency is differentiated, and it can produce to the size of df Certain impact, in actual applications in addition it is also necessary to read fundamental frequency, is calibrated to function f by fundamental frequency, so reads The numerical value taking can be more reliable and more stable.
Inductance coil t1 in Fig. 2 and t2 is two coils being placed in parallel, and mutual distance is close, the magnetic that two coils produce Influence each other, thus affecting the normal work of two agitators, experiment shows, no matter using which type of oscillating circuit, due to The influencing each other so that two agitators cannot normal work simultaneously of two coils.The introducing of fch signal is exactly to be to avoid two coils same When vibration, at a time, only allow one group of coil in vibration, thus eliminating influencing each other of two coils.As institute in Fig. 1 Show, fch is the square wave of input, when fch is for high level, g2 is locked, and t2 stops oscillation, now only t1 normal work;And When fch is for low level, g1 is locked, and t1 stops oscillation, now only t2 normal work.
Fig. 3 is logical block and the calibration being made up of mcu and arithmetic element.Logical block produces square wave fch, the frequency of fch Rate is far below the frequency of oscillation of coil.When fch is in high level, the umber of pulse of the vibration of counter records t1, i.e. t1 counter value, When fch is for low level, the oscillating impulse number of counter records t2, i.e. t2 count value;It is gone out by logic unit operation poor simultaneously Value, i.e. the numerical value of t2-t1.So that above-mentioned 3 numerical value are read by communication control unit in mcu, by calibrating computing, calculate fan The deflection angle of shape metallic plate.
Method of testing based on above-mentioned blood stagnation condition detecting device is specific as follows:
1) system start-up self-inspection;
2) drive elevating mechanism work 6 to make, contact head 2 is stretched in blood vessel 5;
3) rotating seat 4 rotates, heater strip 3 works;
4) mcu exports blood viscosity according to rotating shaft 1 deflection angle;
5) rotating seat 4 rotation and heater strip 3 are closed;
6) drive elevating mechanism work 6 to work, contact head 2 is detached blood vessel 5.
Step 1) in, self-inspection control method is as follows: rotating seat 4 rotation and square-wave generator work;
If rotation speed detection unit detection rotating seat 4 rotating speed is too fast or excessively slow (being compared according to setting value), motivation of adjustment electricity Machine spin down or quickening, until rotating seat 4 rotating speed is normal;
If it is non-zero-degree that mcu detects rotating shaft 1 deflection angle, drive correcting motor adjustment rotating shaft 1 relative position, until Rotating shaft 1 deflection angle is zero degree;
If rotating seat 4 rotating speed and rotating shaft 1 deflection angle are zero degree, execute next step.
If by self-inspection time rating, rotating seat 4 rotating speed still cannot be adjusted to setting speed, or still cannot adjust and turn Axle 1 deflection angle is zero degree, then system is closed and reported to the police.
Ensure that stability and the accuracy of each detection by the self-inspection of step 1.
Above in conjunction with accompanying drawing, the present invention is exemplarily described it is clear that the present invention implements is not subject to aforesaid way Restriction, as long as employing the improvement of various unsubstantialities that method of the present invention design and technical scheme are carried out, or without changing Enter and the design of the present invention and technical scheme are directly applied to other occasions, all within protection scope of the present invention.

Claims (10)

1. blood stagnation condition detecting device it is characterised in that: system include detector unit and be located at detector unit below rotation Turn unit;
Described detector unit is provided with horizontal fixed inductance coil t1 and inductance coil t2, outstanding above or below two inductance coils Sky is provided with fan-shaped metallic plate, and the circle centre position of described sector metallic plate is fixed in the rotating shaft being vertically arranged, and described rotating shaft bottom is solid Surely there is contact head, described rotating shaft is fixed on upper support seat by bearing, be provided with torsion spring between described rotating shaft and bearing, work as rotating shaft During the state that do not stress, described sector metallic plate is identical with the overlapping area of inductance coil t1 and inductance coil t2 respectively, and described two Individual inductance coil is connected with oscillating circuit, and by logical block energy supply, described logical block includes collection vibration to described oscillating circuit The enumerator of channel frequency, the square-wave generator exporting square wave to oscillating circuit and the communication control unit communicating with mcu;
Described rotary unit is fixed on elevating mechanism, and the rotating seat top center that described rotary unit is provided with is provided with and rotates Seat, rotating shaft coaxial blood vessel, the taper type of described rotating seat inner hollow or the structure of cylinder, described rotating seat peripheral hardware Dynamic gear, described power gear is engaged with the driving gear on power motor output shaft, described rotating seat inner hollow area Domain is provided with heated beam, is provided with heater strip and temperature sensor, described heating column top and blood vessel contacts in described heated beam.
2. blood stagnation condition detecting device according to claim 1 it is characterised in that: the NAND gate of described oscillating circuit The one of input of g1 connects the outfan of square-wave generator, outfan two with NAND gate g3 simultaneously of square-wave generator Input connects, and another input of described NAND gate g1 is grounded through electric capacity c1, and described NAND gate g1 outfan connects inductance Coil t1 one end, the described inductance coil t1 other end connects electric capacity c1, the outfan of described NAND gate g3 connect NAND gate g2 its In an input, another input of described NAND gate g2 is grounded through electric capacity c2, described is connected with NAND gate g2 outfan Inductance coil t2 one end, the described inductance coil t2 other end connects electric capacity c2, and described counter input connects NAND gate g4 Outfan, an input of described NAND gate g4 connects NAND gate g1 outfan through resistance r1, described NAND gate g4 another Individual input connects NAND gate g2 outfan through resistance r2.
3. blood stagnation condition detecting device according to claim 1 and 2 it is characterised in that: in described rotating seat top The heart is provided with the putting hole placing blood vessel, and described putting hole medial wall is provided with keyway, described blood vessel lateral wall be provided with The slotting tool of keyway cooperation, is provided with draw-in groove above the slotting tool of described blood vessel lateral wall, and it is described that described rotating seat is provided with clamping The alligator clamp of draw-in groove.
4. blood stagnation condition detecting device according to claim 3 it is characterised in that: described blood vessel be transparent glass Glass vessel, described blood vessel are provided with graduated scale.
5. the blood stagnation condition detecting device according to claim 1,2 or 4 it is characterised in that: described inductance coil t1 It is circular ring structure with inductance coil t2, the area of two inductance coils is identical, adjacent not overlapping to be fixed on the identical of upper support seat Height and position, described inductance coil t1 and inductance coil t2 circle center line connecting and rotating shaft do not stress state when fan-shaped metallic plate axis Line is vertical.
6. blood stagnation condition detecting device according to claim 5 it is characterised in that: described rotating shaft is externally provided with least one Individual support set, described support set is fixed on upper support seat by connecting rod.
7. the blood stagnation condition detecting device according to claim 1 or 6 it is characterised in that: described bearing is fixed on The cylindrical of support base installs intracavity, and described installation cavity bottom is provided with the lower through-hole extending for rotating shaft, described installation cavity top It is provided with the upper through hole extending for calibration of axes, described calibration of axes is coaxial with bearing and affixed, and described calibration of axes is provided with external gear, Described mcu output drive signal is engaged to calibrating motor, the adjustment gear on described calibration motor output shaft with external gear.
8. blood stagnation condition detecting device according to claim 7 it is characterised in that: described rotating seat be provided with rotating speed inspection Survey unit, to mcu, described temperature sensor output temperature signal is to mcu, described for described rotation speed detection unit output speed signal Mcu drives heater strip power supply unit, and the signal output part of described mcu connects display and alarm device.
9. the method for testing based on blood stagnation condition detecting device described in claim 1-8 it is characterised in that:
1) system start-up self-inspection;
2) drive elevating mechanism work, contact head is stretched in blood vessel;
3) rotating seat rotation, heating wire works;
4) mcu exports blood viscosity according to rotating shaft deflection angle;
5) rotating seat rotation and heater strip are closed;
6) drive elevating mechanism work, contact head is detached blood vessel.
10. method of testing according to claim 9 it is characterised in that:
Described step 1) in, rotating seat rotation and square-wave generator work;
If rotation speed detection unit detection rotating seat rotating speed is too fast or excessively slow, motivation of adjustment motor speed slows down or accelerates, until Rotating seat rotating speed is normal;
If it is non-zero-degree that mcu detects rotating shaft deflection angle, drive correcting motor adjustment rotating shaft relative position, until rotating shaft is inclined Gyration is zero degree;
If rotating seat rotating speed and rotating shaft deflection angle are zero degree, execute next step.
CN201610737062.XA 2016-08-26 2016-08-26 Blood stagnation state detection equipment and blood stagnation state detection method Pending CN106353221A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610737062.XA CN106353221A (en) 2016-08-26 2016-08-26 Blood stagnation state detection equipment and blood stagnation state detection method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610737062.XA CN106353221A (en) 2016-08-26 2016-08-26 Blood stagnation state detection equipment and blood stagnation state detection method

Publications (1)

Publication Number Publication Date
CN106353221A true CN106353221A (en) 2017-01-25

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