CN106344019A - Detection capsule with changeable volume - Google Patents
Detection capsule with changeable volume Download PDFInfo
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- CN106344019A CN106344019A CN201610854228.6A CN201610854228A CN106344019A CN 106344019 A CN106344019 A CN 106344019A CN 201610854228 A CN201610854228 A CN 201610854228A CN 106344019 A CN106344019 A CN 106344019A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00131—Accessories for endoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/041—Capsule endoscopes for imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0661—Endoscope light sources
- A61B1/0684—Endoscope light sources using light emitting diodes [LED]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/273—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
- A61B1/2736—Gastroscopes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4222—Evaluating particular parts, e.g. particular organs
- A61B5/4238—Evaluating particular parts, e.g. particular organs stomach
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4261—Evaluating exocrine secretion production
- A61B5/4283—Evaluating exocrine secretion production gastrointestinal secretions, e.g. bile production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6871—Stomach
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Physiology (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention provides a detection capsule with changeable volume. The detection capsule is used for detecting a disease marker in gastric juice. The detection capsule with the changeable volume comprises a main bin and a reaction bin, wherein the main bin comprises a main bin casing, a wireless transmission module, a minicell, a power control module, a signal acquisition circuit and a baffle; the reaction bin has two structures, namely, a first structure and a second structure, the volume of the reaction bin with the first structure changes from small to big and then changes from big to small, and the volume of the reaction bin with the second structure changes from big to small; the first structure of the reaction bin comprises a reaction bin casing, a gastric juice detection sensor, a through hole and a gas forming agent; the second structure of the reaction bin comprises a reaction bin casing, a gastric juice detection sensor, a through hole and an elastic envelope. The detection capsule with the changeable volume has the advantages that the volume of the capsule can become small after detection is completed, the risk caused by the fact that the capsule enters the human body and cannot be discharged is effectively reduced, and various markers can be detected simultaneously.
Description
Technical field
The present invention relates to medicinal detection device, the detection capsule of specifically a kind of variable volume, by capsule of eating, detect
Disease marker in gastric juice.
Background technology
On clinical medicine, the diagnosis of gastropathy mostly from the beginning of the detection of gastric juice, at present, extract gastric juice major way by
In gastroscope, optical microscope is carried out taking liquid to operate from oral cavity insertion stomach, patient suffering is big, although using cooperatively anesthetics,
But still misery is unbearably, and gastroscope also can only extract gastric juice, and other checked operations are to carry out in vitro.
Propose a kind of gastric juice detector in patent cn02268048, with lead, Test paper is bundled into reagent paper group, examination
Spitball is wrapped in solubility big envelope, and the end of lead is placed in outside solubility big envelope.Although patient is easy to use, on the one hand cure
Raw workload is big, when another aspect person under inspection takes reagent paper group, when staying the fine rule of outside and pulling out capsule, can produce evil
The discomfort such as the heart, vomiting, and unhygienic convenience.
A kind of Novel intellectual detection system of gastric fluid occult blood is proposed, this gastric juice is occulted blood detection in patent cn201210134190
Capsule mainly includes gastric juice and occults blood detection module, imageing sensor, microprocessor, signal wireless transmitter module etc., and gastric juice is occulted blood
Detection module detection gastric juice is occulted blood situation assume color change, and imageing sensor acquisition testing result images information, through micro- place
Reason device is launched to external by signal wireless transmitter module after processing.Using this detection capsule of occulting blood, experimenter carries out gastric juice and occults blood
Noinvasive during examination, painless.But due to detecting the restriction of end spaces, the detection mark of this capsule system only only has stomach to occult blood one
Plant it is impossible to detect multiple markers simultaneously.
Content of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of detection capsule of variable volume, can be non-invasively
Disease marker in detection gastric juice, and multiple disease markers, simple to operate, easy to use, disease detection can be detected simultaneously
Accuracy high；After capsule volume diminishes, it is easy to excrete, substantially reduce the risk of capsule detection.
Technical scheme:
The detection capsule of variable volume, including main cabin and reaction cabin, main cabin includes main shell out of my cabin, wireless transmitter module, micro-
Type battery, energy supply control module, signal acquisition circuit and baffle plate；Reaction cabin include reaction cabin shell, gastric juice detection sensor and
Through hole.
Reaction cabin has two kinds of structures, the first structure and second structure, and the reaction cabin volume of the first structure is by little change
Diminish again greatly, the reaction cabin volume of second structure is from large to small；The first structure of described reaction cabin include reaction cabin shell,
Gastric juice detection sensor, through hole and gas-forming agent；The second structure of described reaction cabin includes reaction cabin shell, gastric juice detection sensing
Device, through hole and elastic peplos.
Reaction cabin shell in the first structure of reaction cabin has shape memory function, and material is selected from following material
Kind: inflatable silicon cave, gel, silica gel, high molecular polymer；Reaction cabin enclosure has gas-forming agent, runs into gastric juice and reacts
So that reaction cabin shell expands rapidly, the volume after expansion is 5～20ml to rapid gas generating, is shaped as in following shape
One kind: spheroid, cylinder, cone, spheroid, pyramid, parallelepiped, cube；Gas in question response cabin is complete
After through hole loss is gone out, the reaction cabin shell with shape memory function tightens the shape diminishing into beginning again in portion.
Gas-forming agent form in reaction cabin is graininess, specially the mixture of citric acid and sodium bicarbonate 1:1 in proportion,
Usage amount is 200mg～1000mg, and uniform dispenser is near multiple through holes；It is covered with sugar-coat film, sugar-coat film is very soft, very inside through hole
Thin, water breakthrough easily dissolves；The number of through hole is 2～5, and the area of each through hole is 0.3～1.0mm2, total face of all through holes
After the long-pending expansion with reaction cabin shell, area ratio is 1:500～1:5000.
Reaction cabin shell degradable in reaction cabin second structure, material is selected from one of following material: Lac, poly-
Vinyl alcohol acetate phthalate ester, acrylic resin, cellulose acetate phthalate, phthalic acid hydroxypropyl methyl fiber
Element, polylactic acid；The inwall of reaction cabin shell all bonds flexible peplos, and the top edge of elastic peplos is bonded in main shell out of my cabin
Edge outside；Elastic peplos have elasticity, are in extended state when being bonded to reaction cabin outer casing inner wall, question response shell out of my cabin
After degradable, elastic film shrinks immediately, and the material that it is selected is specially one of following material: inflatable silicon cave, solidifying
Glue, silica gel, high molecular polymer.
Described baffle plate selects transparent material, and the excircle glue of baffle plate is fixed in inside capsule wall it is impossible to move；Described
Minicell adopts three pieces of button cells.
Described gastric juice detection sensor is Test paper or reagent or electrode or more combination in any；Test paper be selected from
Under one or more: hemoglobin Test paper, transferrinss Test paper, detecting paper for pylorus spiral bacillus and cancer embryo
Detection of antigen reagent paper；Detecting electrode is selected from following one or more: ph detecting electrode, hemoglobin detecting electrode and temperature
Detecting electrode.
The signal that described signal acquisition circuit is gathered is one or more of signals below form: picture signal, numeral
Encoded signal, optical signal, current signal, voltage signal, pressure signal, electromagnetic signal.
The work process of the present invention:
Reaction cabin adopts the work process of the detection capsule of the first structure: the detection capsule of described variable volume is by oral administration
Enter gastric, gastric juice dissolves sugar-coat film, enters reaction cabin by through hole, reaction cabin shell is in deflated state when starting, inside
Gastric juice detection sensor also tightens or is gathered in wherein, and gastric juice contacts a large amount of gases of generation that react with gas-forming agent, suddenly increases
Many gas makes reaction cabin shell expand, and internal gastric juice detection sensor is also unfolded or scattered, and detects the mark in gastric juice
Thing information, signal acquisition circuit gathers the detection information of gastric juice detection sensor, is then transferred to body by wireless transmitter module
Outward.Carrying out with marker detection in gastric juice and the gradually spilling of gas, the shell of expansion is retracted to original shape again,
Before retraction original state, marker detection has completed.
Reaction cabin adopts the work process of the detection capsule of second structure: the detection capsule of described variable volume is by oral administration
Enter gastric, gastric juice enters reaction cabin by through hole, and gastric juice detection sensor is contacted with gastric juice, the letter of detection disease of stomach mark
Breath, signal acquisition circuit gathers and processes the information that gastric juice detection sensor detects, and detection information is sent out by wireless transmitter module
Deliver to external；After capsule detection completes, enter small intestinal, reaction cabin shell is gradually degraded, and elastic peplos also gradually taper up and diminish.
The detection capsule of variable volume provided by the present invention, after detection completes, capsule volume can diminish, and effectively reduces
Capsule enters the risk that human body cannot be discharged；Reaction cabin adopts the detection capsule of the first structure at the beginning, and reaction cabin is just located
In deflated state, decrease the sense of discomfort that person under inspection swallows；The detection capsule of variable volume provided by the present invention can be with noinvasive
Disease marker in ground detection gastric juice, and multiple markers can be detected simultaneously, simple to operate, easy to use, disease detection
Accuracy is high.
Brief description:
Fig. 1 is the detection capsule structure schematic diagram of the variable volume of the present invention；
Fig. 2 is detection the first structural representation of capsule reaction cabin of variable volume；
Fig. 3 is the detection capsule reaction cabin second structural representation of variable volume；
Fig. 4 is the detection capsule structure schematic diagram of the embodiment of the present invention one；
Fig. 5 is the detection capsule structure schematic diagram of the embodiment of the present invention two；
Fig. 6 is the positive findingses schematic diagram of the embodiment of the present invention one and embodiment two gastric juice detection sensor.
In Fig. 1 to Fig. 6:
The main cabin of 1 ━, 2 ━ reaction cabins, 3 ━ masters shell, 4 ━ reaction cabin shells, 4a ━ reaction cabin shell, 4b ━ reaction cabin out of my cabin
Shell, 5 ━ wireless transmitter modules, 6 ━ minicells, 7 ━ energy supply control modules, 8 ━ signal acquisition circuits, 9 ━ gastric juice detections
Sensor, 10 ━ baffle plates, 11 ━ through holes, 12 ━ hemoglobin Test papers, 13 ━ carcinoembryonic antigen Test papers, 14 ━ elasticity bags
Film, 15 ━ microcontrollers, 16 ━ LED lamp groups, 17 ━ cmos sensors, 18 ━ gas-forming agents.
Specific embodiment
Embodiment one
As shown in figure 4, a kind of detection capsule of variable volume, including main cabin 1 and reaction cabin 2, main cabin 1 includes main shell out of my cabin
3rd, wireless transmitter module 5, minicell 6, energy supply control module 7, microcontroller 15, cmos sensor 17, LED lamp group 16 and gear
Plate 10；Reaction cabin 2 includes reaction cabin shell 4a, hemoglobin Test paper 12, carcinoembryonic antigen Test paper 13, through hole 11 and makes
Gas agent 18.
Reaction cabin shell 4a has shape memory function, and material is inflatable silicon cave；Reaction cabin enclosure has gas-forming agent
18, run into gastric juice and react quick release gas so that reaction cabin shell 4a expands rapidly, the volume after expansion be 5～
20ml, is shaped as spheroid；Gas in question response cabin 2 all, after through hole 11 loss is gone out, has shape memory work(
The reaction cabin shell 4a of energy tightens the shape diminishing into beginning again.
The detection capsule through hole 11 of the present embodiment one has three, hemoglobin Test paper 12 and carcinoembryonic antigen Test paper
13 test side is pasted onto at two through holes 11, and the other end is placed naturally, and the area of each through hole is 0.3～1.0mm2, own
After the gross area of through hole 11 is expanded with reaction cabin shell 4a, area ratio is 1:500～1:5000.Gas-forming agent in reaction cabin 2
18 forms are powdery or granule, specially the mixture of citric acid and sodium bicarbonate 1:1 in proportion, usage amount be 200mg～
1000mg, uniform dispenser is near three through holes；It is covered with sugar-coat film, sugar-coat film is very soft, very thin, water breakthrough is easily molten inside through hole 11
Solution.
Baffle plate 10 selects transparent material, and the excircle glue of baffle plate 10 is fixed in inside capsule wall it is impossible to move；Miniature
Battery 6 adopts three pieces of button cells；The lampet number of LED lamp group 16 is 2～4, and using paster type light emitting type, color is adopted
With white light, and irradiate for astigmatism.
As shown in fig. 6, the positive findingses signal detecting capsule hemoglobin and carcinoembryonic antigen detection for the present embodiment one
Figure, hemoglobin Test paper 12 and carcinoembryonic antigen Test paper 13 are all made using colloidal gold immunity chromatography, specificity pin
To human hemoglobin and carcinoembryonic antigen, and detection sensitivity is high, if there is hemoglobin in gastric juice, hemoglobin Test paper
12 two red lines of display, if not existing, show a red line；In the same manner, if there being carcinoembryonic antigen in gastric juice, carcinoembryonic antigen is examined
Test paper 13 shows two red lines, if not existing, shows a red line.
The work process of the present embodiment one is as follows: person under inspection takes the detection capsule into variable volume with warm water, and capsule enters
Stomach and starting working, gastric juice dissolves sugar-coat film, enters reaction cabin 2 by through hole 11, reaction cabin shell 4a is in deflation when starting
State, internal hemoglobin Test paper 12 and carcinoembryonic antigen Test paper 13 also tighten in wherein, gastric juice and gas-forming agent 18
Contact reacts and produces a large amount of gases, and the gas suddenly increasing makes reaction cabin shell 4a expand, and internal hemoglobin detects
Reagent paper 12 is also unfolded with carcinoembryonic antigen Test paper 13 and is come, and gastric juice chromatographs and occur along reagent paper chromogenic reaction, cmos upwards
Sensor 17 collects the color change of two reagent paper, then carries out certain process via microcontroller 15, finally by wirelessly sending out
Penetrate module 5 to be sent in vitro.With the gradually spilling of carrying out and the gas of marker detection in gastric juice, and reaction cabin shell 4a
Shape memory effect, the shell of expansion is retracted to original shape again, and gastric juice detection before retraction original state has completed.Inspection
Survey if two red lines in hemoglobin Test paper 12 in result, then explanation stomach has bleeding；If carcinoembryonic antigen detects
Two red lines in reagent paper 13, then contain a certain amount of carcinoembryonic antigen in explanation gastric juice.
Embodiment two
As shown in figure 5, a kind of detection capsule of variable volume, including main cabin 1 and reaction cabin 2, the present embodiment two and enforcement
Example one is compared, and the structure in main cabin 1 is just the same with implementation method, and the structure of reaction cabin 2 and implementation method have difference.
The reaction cabin 2 of the present embodiment two includes reaction cabin shell 4b, hemoglobin Test paper 12, carcinoembryonic antigen detection examination
Paper 13, through hole 11 and elastic peplos 14.
Reaction cabin shell 4b degradable, material is PVAP；The inwall of reaction cabin shell 4b glues
Close flexible peplos 14, the top edge of elastic peplos 14 is bonded in outside the main edge of shell 3 out of my cabin；Elastic peplos 14 have bullet
Property, is in extended state when being bonded to reaction cabin shell 4b inwall, question response is after shell 4b is degradable out of my cabin, elastic film 14
Shrink immediately, its material is inflatable silicon cave.
The detection capsule through hole 11 of embodiment two has two, hemoglobin Test paper 12, carcinoembryonic antigen Test paper 13
Test side be pasted onto at two through holes 11, the other end is placed naturally.
As shown in fig. 6, the positive findingses signal detecting capsule hemoglobin and carcinoembryonic antigen detection for the present embodiment two
Figure, hemoglobin Test paper 12 and carcinoembryonic antigen Test paper 13 are all made using colloidal gold immunity chromatography, specificity pin
To human hemoglobin and carcinoembryonic antigen, and detection sensitivity is high, if there is hemoglobin in gastric juice, hemoglobin Test paper
12 two red lines of display, if not existing, show a red line；In the same manner, if there being carcinoembryonic antigen in gastric juice, carcinoembryonic antigen is examined
Test paper 13 shows two red lines, if not existing, shows a red line.
The work process of the present embodiment two is as follows: person under inspection takes the detection capsule into variable volume with warm water, and capsule enters
Stomach and starting working, gastric juice enters reaction cabin 2, the hemoglobin Test paper 12 in reaction cabin 2 and cancer embryo via through hole 11
Detection of antigen reagent paper 13 is contacted with gastric juice, and gastric juice chromatographs and occur along reagent paper chromogenic reaction upwards, and cmos sensor 17 gathers
To the color change of two reagent paper, then carry out certain process via microcontroller 15, be finally sent to by wireless transmitter module 5
In vitro.After capsule detection completes, enter small intestinal, reaction cabin shell 4b gradually degrades, and elastic peplos 14 also gradually taper up and diminish,
Excrete.If two red lines in hemoglobin Test paper 12 in testing result, then explanation stomach has bleeding；If cancer
Two red lines in embryonal antigen Test paper 13, then contain a certain amount of carcinoembryonic antigen in explanation gastric juice.
The present invention is not limited to above-mentioned specific embodiment, according to the above, according to the ordinary technical knowledge of this area
And customary means, under the premise of without departing from the present invention above-mentioned basic fundamental thought, the present invention can also make other various ways
Equivalent modifications, replacement or change, all fall among protection scope of the present invention.
Claims (10)
1. a kind of detection capsule of variable volume is it is characterised in that described detection capsule includes main cabin (1) and reaction cabin (2), its
In, main cabin (1) includes master, and shell (3), wireless transmitter module (5), minicell (6), energy supply control module (7), signal are adopted out of my cabin
Collector (8) and baffle plate (10), reaction cabin (2) includes reaction cabin shell (4), gastric juice detection sensor (9) and through hole (11), institute
State reaction cabin (2) variable volume, and have two kinds of structures, the first structure and second structure, the reaction cabin (2) of the first structure
Volume is changed from small to big and is diminished, and reaction cabin (2) volume of second structure is from large to small；The first knot of described reaction cabin (2)
Structure includes reaction cabin shell (4a), gastric juice detection sensor (9), through hole (11) and gas-forming agent (18)；The of described reaction cabin (2)
Two kinds of structures include reaction cabin shell (4b), gastric juice detection sensor (9), through hole (11) and elastic peplos (14).
2. the detection capsule of variable volume according to claim 1 is it is characterised in that described reaction cabin shell (4a) has
Shape memory function, material is selected from one of following material: inflatable silicon cave, gel, silica gel, high molecular polymer；Expand
Volume afterwards is 5～20ml, is shaped as one of following shape: spheroid, cylinder, cone, ball after expansion
Body, pyramid, parallelepiped, cube.
3. the detection capsule of variable volume according to claim 1 is it is characterised in that described reaction cabin shell (4b) can drop
Solution, material is selected from one of following material: Lac, PVAP, acrylic resin, phthalic acid
Cellulose acetate, Hydroxypropyl Methylcellulose Phathalate, polylactic acid.
4. variable volume according to claim 1 detection capsule it is characterised in that described reaction cabin shell (4b) interior
Wall all bonds flexible peplos (14), and the top edge of elastic peplos (14) is bonded in outside the main edge of shell (3) out of my cabin, elasticity
Peplos (14) select elastomeric material, one of specially following material: inflatable silicon cave, gel, silica gel, high molecular polymerization
Thing.
5. the detection capsule of variable volume according to claim 1 is it is characterised in that described baffle plate (10) is transparent.
6. variable volume according to claim 1 detection capsule it is characterised in that described reaction cabin (2) the first knot
It is covered with sugar-coat film inside through hole (11) in structure.
7. variable volume according to claim 1 detection capsule it is characterised in that described reaction cabin (2) the first knot
The number of the through hole (11) in structure is 2～5, and the area of each through hole is 0.3～1.0mm2, the gross area of all through holes with anti-
After answering shell (4a) expansion out of my cabin, area ratio is 1:500～1:5000.
8. the detection capsule of variable volume according to claim 1 is it is characterised in that the form of described gas-forming agent (18) is
The mixture of powdery or granule, specially citric acid and sodium bicarbonate 1:1 in proportion, usage amount is 200mg～1000mg, uniformly
Dispenser is near multiple through holes.
9. the detection capsule of variable volume according to claim 1 is it is characterised in that described gastric juice detection sensor (9)
For Test paper or reagent or electrode or more combination in any；
Test paper is selected from following one or more: hemoglobin Test paper, transferrinss Test paper, H. pylori
Bacterium Test paper and carcinoembryonic antigen Test paper；
Detecting electrode is selected from following one or more: ph detecting electrode, hemoglobin detecting electrode and temperature detection electrode.
10. the detection capsule of variable volume according to claim 1 is it is characterised in that described signal acquisition circuit (8) institute
The signal of collection is one or more of signals below form: picture signal, digitally encoded signal, optical signal, current signal, electricity
Pressure signal, pressure signal, electromagnetic signal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610854228.6A CN106344019A (en) | 2016-09-27 | 2016-09-27 | Detection capsule with changeable volume |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610854228.6A CN106344019A (en) | 2016-09-27 | 2016-09-27 | Detection capsule with changeable volume |
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| CN106344019A true CN106344019A (en) | 2017-01-25 |
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| CN201610854228.6A Pending CN106344019A (en) | 2016-09-27 | 2016-09-27 | Detection capsule with changeable volume |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108553076A (en) * | 2018-05-11 | 2018-09-21 | 苏州市奇捷生物科技有限公司 | A kind of electric actuation capsule gastroscope and its control method |
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| CN101721194A (en) * | 2008-10-14 | 2010-06-09 | 鸿富锦精密工业（深圳）有限公司 | Capsule endoscope and method for manufacturing lenses thereof |
| CN102631183A (en) * | 2012-05-03 | 2012-08-15 | 重庆大学 | Novel intellectual detection system of gastric fluid occult blood |
| CN105813536A (en) * | 2013-10-22 | 2016-07-27 | 吕甘雨 | System and method for capsule device with multiple phases of density |
| CN206365892U (en) * | 2016-09-27 | 2017-08-01 | 重庆大学 | A kind of gastric juice detects capsule |
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