CN106334123A - Traditional Chinese medicine decoction for treating ankylosing spondylitis and preparation method thereof - Google Patents

Traditional Chinese medicine decoction for treating ankylosing spondylitis and preparation method thereof Download PDF

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CN106334123A
CN106334123A CN201611001997.8A CN201611001997A CN106334123A CN 106334123 A CN106334123 A CN 106334123A CN 201611001997 A CN201611001997 A CN 201611001997A CN 106334123 A CN106334123 A CN 106334123A
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黄兆龙
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/264Aristolochia (Dutchman's pipe)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
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    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention discloses a traditional Chinese medicine decoction for treating ankylosing spondylitis. The traditional Chinese medicine decoction is prepared from, by weight, 10-20 g of thuja sutchuenensis,10-20 g of pine needles, 5-15 g of tuberculate speranskia herb, 5-15 g of bark of eucommia, 3-7 g of herba asari, 2-6 g of radix notoginseng, 3-7 g of tea tree roots and 3-7 g of lalang grass rhizomes. All the bulk drugs are mixed together and decocted twice by adding 1,500 ML of water in each time of decocting, wherein in first-time decocting, the mixed bulk drugs are soaked for 30 minutes and then decocted to be boiled on strong fire for 30 minutes, the fire is turned off for 20 minutes, and in second-time decocting, the mixed bulk drugs are decocted on slow fire for 20 minutes, and when the 1,500 ML of water is decocted into 500 ML of water, the decoction is obtained. The traditional Chinese medicine decoction has the effects of dispelling wind, eliminating dampness, activating meridians to stop pain, promoting blood circulation to remove blood stasis, dredging meridians, tonifying the liver and the kidney and strengthening bones and muscles, is effectively used for treating the ankylosing spondylitis, can enable original cancerized and stiff muscles of spines to become soft, is rich in raw material, low in cost, safe in medication, free of toxic and side effects and good in using effect and is a creative drug for treating the ankylosing spondylitis.

Description

A kind of treat Chinese medicine decoction of ankylosing spondylitiss and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine, specifically a kind of treat Chinese medicine decoction of ankylosing spondylitiss and preparation method thereof.
Background technology
Ankylosing spondylitises (as) are complete based on a kind of chronic inflammatory disease with middle axis joint and tendon ligament bone attachment point Body disease, with inflammatory lumbago, Enthesitis, periphery arthritis and extra-articular manifestation as feature.Mainly involve sacroiliac joint, ridge Post and extremities joint, show as joint and periarticular tissue, ligament, the calcification of intervertebral disc, and articuli intervertebraleses and extremities joint are slided The hypertrophy of film, finally develops into bony ankylosiss.Adopting nonsteroidal antiinflammatory drug, sulfasalazine, first ammonia butterfly Western medicine at present more Purine, glucocorticoid etc., though having certain curative effect, Long term combined medication to most of patients, may result in Liver and kidney toxicity, sclerotin to dredge The untoward reaction such as pine, bone marrow depression, reproduction suppression.Biological preparation (as antitnf- alpha monoclonal antibodies) makes us bulging though achieving The curative effect of dance, but expensive, and have induction tuberculosis and potential oncogenic risk.Chinese medicine control ankylosing spondylitiss have more Advantage, respond well, but lack the medicine of this respect it is impossible to meet the needs of clinical treatment.Therefore, ankylosing spondylitises are treated Improvement on medicine is the problem of current urgent need to resolve.
Content of the invention
It is an object of the invention to provide a kind of instant effect, effect good treatment ankylosing spondylitiss Chinese medicine decoction and its Preparation method, to solve the problems, such as to propose in above-mentioned background technology.
For achieving the above object, the following technical scheme of present invention offer:
A kind of Chinese medicine decoction treating ankylosing spondylitiss, raw material in parts by weight includes: Cui Bai 10-20g, pine Pin 10-20g, Herba speranskiae tuberculatae 5-15g, Cortex Eucommiae 5-15g, Herba Asari 3-7g, Radix Notoginseng 2-6g, Radix Camelliae sinensiss 3-7g, Rhizoma Imperatae 3-7g.
As the further scheme of the present invention: raw material in parts by weight includes: Cui Bai 12-18g, Folium Pini 12- 18g, Herba speranskiae tuberculatae 8-12g, Cortex Eucommiae 8-12g, Herba Asari 4-6g, Radix Notoginseng 3-5g, Radix Camelliae sinensiss 4-6g, Rhizoma Imperatae 4-6g.
As the further scheme of the present invention: the raw material according to weight portion includes: Cui Bai 15g, Folium Pini 15g, Herba speranskiae tuberculatae 10g, Cortex Eucommiae 10g, Herba Asari 5g, Radix Notoginseng 4g, Radix Camelliae sinensiss 5g, Rhizoma Imperatae 5g.
The preparation method of the Chinese medicine decoction of described treatment ankylosing spondylitiss, concrete steps include:
Cui Bai, Folium Pini, Herba speranskiae tuberculatae, the Cortex Eucommiae, Herba Asari, Radix Notoginseng, Radix Camelliae sinensiss, Rhizoma Imperatae are mixed, adds every time The decocting of 1500ml boils twice;First soak 30 minutes for the first time, intense fire is fried boiling 30 minutes, cease fire 20 minutes, turn slow fire for the second time Decoct 20 minutes, 1500ml decocting in water becomes 500ml, that is, obtain decoction.
Compared with prior art, the invention has the beneficial effects as follows: the present invention has expelling wind and removing dampness, removing obstruction in the collateral to relieve pain;Promoting blood circulationization The stasis of blood, qualcomm meridian;Invigorating the liver and kidney, effect of bone and muscle strengthening, effective for treating ankylosing spondylitises, and the canceration of original spinal column can be made stiff Hard muscle becomes soft, abundant raw material, with low cost, drug safety, has no toxic side effect, using effect is good, is that treatment is tetanic Innovation on property spondylitiss medicine.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of not making creative work, all Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of Chinese medicine decoction treating ankylosing spondylitiss, the raw material according to weight portion includes: Cui Cypress 12g, Folium Pini 16g, Herba speranskiae tuberculatae 8g, Cortex Eucommiae 11g, Herba Asari 6g, Radix Notoginseng 4g, Radix Camelliae sinensiss 4g, Rhizoma Imperatae 5g.
The preparation method of the Chinese medicine decoction of described treatment ankylosing spondylitiss, concrete steps include:
Cui Bai 12g, Folium Pini 16g, Herba speranskiae tuberculatae 8g, Cortex Eucommiae 11g, Herba Asari 6g, Radix Notoginseng 4g, Radix Camelliae sinensiss 4g, Rhizoma Imperatae 5g are mixed It is combined, add the decocting of 1500ml to boil twice every time, first soak 30 minutes for the first time, intense fire is fried boiling 30 minutes, truce 20 Minute, second turn boils by slow fire 20 minutes, 1500ml decocting in water is become 500ml, that is, obtains decoction.
Embodiment 2
In the embodiment of the present invention, a kind of Chinese medicine decoction treating ankylosing spondylitiss, the raw material according to weight portion includes: Cui Bai 15g, Folium Pini 12g, Herba speranskiae tuberculatae 7g, Cortex Eucommiae 8g, Herba Asari 5g, Radix Notoginseng 3g, Radix Camelliae sinensiss 5g, Rhizoma Imperatae 6g.
The preparation method of the Chinese medicine decoction of described treatment ankylosing spondylitiss, concrete steps include:
By Cui Bai 15g, Folium Pini 12g, Herba speranskiae tuberculatae 7g, Cortex Eucommiae 8g, Herba Asari 5g, Radix Notoginseng 3g, Radix Camelliae sinensiss 5g, Rhizoma Imperatae 6g mix Together, add the decocting of 1500ml to boil twice every time, first soak 30 minutes for the first time, intense fire is fried boiling 30 minutes, cease fire 20 points Clock, second turn boils by slow fire 20 minutes, 1500ml decocting in water is become 500ml, that is, obtains decoction.
Embodiment 3
In the embodiment of the present invention, a kind of Chinese medicine decoction treating ankylosing spondylitiss, the raw material according to weight portion includes: Cui Bai 10g, Folium Pini 18g, Herba speranskiae tuberculatae 5g, Cortex Eucommiae 6g, Herba Asari 7g, Radix Notoginseng 5g, Radix Camelliae sinensiss 4g, Rhizoma Imperatae 4g.
The preparation method of the Chinese medicine decoction of described treatment ankylosing spondylitiss, concrete steps include:
By Cui Bai 10g, Folium Pini 18g, Herba speranskiae tuberculatae 5g, Cortex Eucommiae 6g, Herba Asari 7g, Radix Notoginseng 5g, Radix Camelliae sinensiss 4g, Rhizoma Imperatae 4g mix Together, add the decocting of 1500ml to boil twice every time, first soak 30 minutes for the first time, intense fire is fried boiling 30 minutes, cease fire 20 points Clock, second turn boils by slow fire 20 minutes, 1500ml decocting in water is become 500ml, that is, obtains decoction.
In prescription of the present invention, Cui Bai has functions that Os Sus domestica, antiinflammatory, removing toxic substances, antiinflammatory;Folium Pini has double items and adjusts blood pressure Effect, vessel softening, reduce hyperlipidemia, can effective enhancing immunity effect;Herba speranskiae tuberculatae have expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, Dissipating blood stasis for subsidence of swelling, removing toxic substances ophthalmalgia, main air pain of dampness syndrome, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, lumbar strain, paralysis, effect of sore furuncle poison, There is special effect for treating rheumatic arthritis;The Cortex Eucommiae have invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, etc. many effects.Spinal column acid can be controlled Pain, limbs impotence weak, asthenia, hypertension etc.;Herba Asari has functions that antipyretic, diuresis, analgesia, expelling wind and cold, and Radix Notoginseng has promoting blood circulation Hemostasis, defying age, blood sugar lowering, improve body's immunity.It is mainly used in treating:Coronary heart disease, angina pectoriss, headache, dizziness, high blood Pressure, arrhythmia, hyperlipidemia etc..Radix Camelliae sinensiss have heart tonifying diuresis;Promoting blood flow to regulate menstruationHeat-clearing and toxic substances removingEffect, be mainly used inThe heart Disease of ZANG-organsEdemaHepatitisDeng Rhizoma Imperatae has functions that removing heat from blood, hemostasis, heat clearing away, diuresis, is mainly used in pyreticosis polydipsia, lung-heat is breathed heavily Anxious, gastric heat hiccup, edema, jaundice etc., Rhizoma Imperatae is cold in nature, also has antiinflammatoryEffect.Each medicine shares and plays expelling wind and removing dampness altogether above, and dredging collateral stops Bitterly;The promoting blood circulation stasis of blood, qualcomm meridian;Invigorating the liver and kidney, bone and muscle strengthening, above-mentioned raw materials medicine, through dialectical compatibility, can effectively give play to replenishing kidney, strengthening waist Effect, to reach the purpose curing ankylosing spondylitises, good effect, expense is low, has no toxic side effect, and obtains through clinical data Fully prove, relevant case-data is as follows:
1. case-data
Liu Kai, man, existing 39 years old, identification card number: 420606197710093530, no substantially lumbosacral region in inducement the year before Pain, with from morning, front symptom mitigation or disappearance for after activity of very, getting up, due to not affecting studying and living, and does not arouse attention. Exacerbation of symptoms afterwards, and double knee joint occurs swell and ache, night stands up difficulty, morning stiffness substantially, with soreness of the waist and knees, fatigue and asthenia, night Between the symptom such as night sweat.Clinical examination: hla-b27 is positive, esr36mm/h, rf (-).L spine ap & lat piece and bilateral sacroiliac joint P-A Cephalomatrics show: lumbar vertebra is without exception, and bilateral sacroiliac joint gap is unchanged, and sacroiliac joint bone density increases, edge blurry, locally Worm-eaten sample is had to change.It is diagnosed as ankylosing spondylitises (in early days).Upon somebody's introduction, take Chinese medicine decoction of the present invention, after ten days, morning Deadlock, waist and sacrum pain, night stands up difficulty and double knee joint pain symptom and disappears, and only sense right hips are ached, when have night Night sweat.After 40 days, right hips are ached, and Sleeps hyperhidrosis symptom disappears.Take 30 days again and consolidated curative effect, checked erythrocyte sedimentation rate Recover normal, hla-b27 is normal.Then take the circumstances into consideration to adjust and reduce dose and dealt with problems arising from an accident with nursing one's health, follow-up is not recurred so far.
2. case-data
Field literary riddles, man, 46 years old.Identification card number: 420621197012083937, patient is diagnosed as suffering from May, 2002 Ankylosing spondylitiss, visit national many places large hospital and seek medical advice, curative effect is all inconspicuous.On inspection, clinical symptoms are floating and rapid pulse, tongue Red dry, rough and yellow fur, complexion sallow, constipation, head and neck trunk rotates difficulty, and both legs are heavy to ache, and sacroiliac joint swells, and independent ambulation is stranded Difficult.Take Chinese medicine preparation of the present invention after ten days, patient's head and neck trunk motility is obviously improved, and both legs start effectively, can independent rows Walk.Added and subtracted with disease according to its PD afterwards, continue to take medicine of the present invention 60 days, patient's back is upright and left-right rotation just Often, freely, general joint pain disappears for walking.Follow-up and nearest return visit after half a year, patient is physically and mentally healthy.
3. case-data
Gong Lingling, female, 30 years old, identification card number: 411502198602019328.Patient's no substantially inducement appearance before 2 years Waist, hip joint are uncomfortable, deadlock plate sense in back from morning, and pain increases to the cold to the wind, stands up difficulty within nearly 2 months, and during cough, sternal body is acute Bitterly, limited by bending over, not good enough, multi-treatment effect on driving birds is not good of sleeping, clinical examination shows, lumbar lateral curvature, sacrocoxitis, and tongue body is fertile Fat, thin and yellow fur, the test of " 4 " word (+), limited by squatting up.Previously healthy, no family's hereditary history.It is diagnosed as tatanic Spondylitises.Start upon somebody's introduction to take Chinese medicine preparation of the present invention and treated, after 10 days, patient's cough symptom disappears, squatting up, curved Waist mobility increases, sleep improvement;After continuing to take three months, clinical examination, uncomfortable symptom all disappears, and dirty power is put down With.Follow-up is no recurred so far.
4. medical history information
Chen Yanhong, female, 30 years old.Identification card number: 410106198611161521.Patient felt pain in the lumbar region before 2 years, did not exist Meaning, pain increases after two months, goes to bed, the very important person that leaves the bed embraces, and can not stand up at night, hurt like hell, limitation of activity, has almost moved light Raw thought.Through examination in hospital, patient's pelvis substantially projects, and making a definite diagnosis is ankylosing spondylitiss.Start upon somebody's introduction to take this Bright Chinese medicine preparation, after 15 days, pelvis shrinkage phenomenon substantially, continues to take three months, and patient's pelvis recovers normal, lumbago symptom Disappear, activity is freely.Follow-up is no recurred so far.
5. medical history information
Kong Heng, man, 29 years old.Identification card number: 42088119870403****, patient's in September, 2013 is diagnosed as with strong Straightforward spondylitises, visit national many places large hospital and seek medical advice, curative effect is all inconspicuous.On inspection, making a definite diagnosis is ankylosing spondylitiss, solely Vertical difficulty in walking, is lifted when seeking medical advice.Take Chinese medicine preparation of the present invention after 15 days, patient's head and neck trunk is flexible Property is obviously improved, and both legs start effectively, can independent ambulation, continue to take medicine of the present invention 60 days, patient's back is upright and left Turn right dynamic normal, freely, general joint pain disappears for walking.Follow-up is no recurred so far.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of the spirit or essential attributes of the present invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit requires rather than described above limits, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment only wraps Containing an independent technical scheme, only for clarity, those skilled in the art should for this narrating mode of description Using description as an entirety, the technical scheme in each embodiment can also form those skilled in the art through appropriately combined Understandable other embodiment.

Claims (4)

1. a kind of Chinese medicine decoction treating ankylosing spondylitiss is it is characterised in that raw material in parts by weight includes: Cui Bai 10-20g, Folium Pini 10-20g, Herba speranskiae tuberculatae 5-15g, Cortex Eucommiae 5-15g, Herba Asari 3-7g, Radix Notoginseng 2-6g, Radix Camelliae sinensiss 3-7g, Rhizoma Imperatae 3- 7g.
2. the Chinese medicine decoction for the treatment of ankylosing spondylitiss according to claim 1 is it is characterised in that in parts by weight Raw material include: Cui Bai 12-18g, Folium Pini 12-18g, Herba speranskiae tuberculatae 8-12g, Cortex Eucommiae 8-12g, Herba Asari 4-6g, Radix Notoginseng 3-5g, Camellia sinensis Root 4-6g, Rhizoma Imperatae 4-6g.
3. the Chinese medicine decoction for the treatment of ankylosing spondylitiss according to claim 2 is it is characterised in that former according to weight portion Material includes: Cui Bai 15g, Folium Pini 15g, Herba speranskiae tuberculatae 10g, Cortex Eucommiae 10g, Herba Asari 5g, Radix Notoginseng 4g, Radix Camelliae sinensiss 5g, Rhizoma Imperatae 5g.
4. the preparation method of the Chinese medicine decoction according to the arbitrary described treatment ankylosing spondylitiss of claim 1-3, its feature exists In concrete steps include: Cui Bai, Folium Pini, Herba speranskiae tuberculatae, the Cortex Eucommiae, Herba Asari, Radix Notoginseng, Radix Camelliae sinensiss, Rhizoma Imperatae are mixed, often The decocting of secondary addition 1500ml boils twice;First soak 30 minutes for the first time, intense fire is fried boiling 30 minutes, cease fire 20 minutes, second Turn and boil by slow fire 20 minutes, 1500ml decocting in water becomes 500ml, that is, obtain decoction.
CN201611001997.8A 2016-11-15 2016-11-15 Traditional Chinese medicine decoction for treating ankylosing spondylitis and preparation method thereof Pending CN106334123A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1977963A (en) * 2005-11-30 2007-06-13 辽宁中医学院附属医院 External Chinese medicine for treating ankylosing spondylitis
CN103520662A (en) * 2013-08-28 2014-01-22 李新民 Traditional Chinese medicine formula for treating ankylosing spondylitis
CN104069205A (en) * 2014-07-15 2014-10-01 孙朝辉 Traditional Chinese medicine preparation for treating Ankylosing spondylitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1977963A (en) * 2005-11-30 2007-06-13 辽宁中医学院附属医院 External Chinese medicine for treating ankylosing spondylitis
CN103520662A (en) * 2013-08-28 2014-01-22 李新民 Traditional Chinese medicine formula for treating ankylosing spondylitis
CN104069205A (en) * 2014-07-15 2014-10-01 孙朝辉 Traditional Chinese medicine preparation for treating Ankylosing spondylitis

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Application publication date: 20170118