CN106334061A - Pharmaceutical composition for treating traumatic injuries and preparation method thereof - Google Patents

Pharmaceutical composition for treating traumatic injuries and preparation method thereof Download PDF

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Publication number
CN106334061A
CN106334061A CN201610638502.6A CN201610638502A CN106334061A CN 106334061 A CN106334061 A CN 106334061A CN 201610638502 A CN201610638502 A CN 201610638502A CN 106334061 A CN106334061 A CN 106334061A
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parts
radix
rhizoma
borneolum syntheticum
pharmaceutical composition
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蔡志勇
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
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Abstract

The invention discloses a pharmaceutical composition for treating traumatic injuries and a preparation method thereof; the pharmaceutical composition is prepared by adopting anomalous wormwood, rhizoma dioscoreae nipponicae, acanthopanax bark, sapanwood, radix aconiti, radix aconiti agrestis, angiopteris fokiensis hieron, rhizoma drynariae, radix angelicae sinensis, radix angelicae, ligusticum wallichii, radix stephaniae tetrandrae, konjac, frankincense, myrrh, safflower, fructus aurantii immaturus, radix aucklandiae, fruit of sambucus chinensis lindl., cape jasmine, natural copper, white mustard seed, sambucus chinensis, radix fici hirtae, speranskia tuberculata, clam shell, camphor, radix angelicae lateralis preparata, rheum officinale, borneol, radix dipsaci, rhizoma atractylodis, pseudo-ginseng, cassia twig, radix achyranthis bidentatae, pine nodular branch and herba siegesbeckiae to cooperate with 56-degree wine, has the effects of promoting blood circulation and removing blood stasis, expelling wind and dampness, nourishing liver and kidney, and strengthening bones and muscles, and has good curative effect on various traumatic injuries and rheumatism bone pain and other symptoms.

Description

A kind of for treating pharmaceutical composition of traumatic injury and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines is and in particular to a kind of pharmaceutical composition for treating traumatic injury and its preparation side Method.
Background technology
How traumatic injury is caused by external force effect, the skin of coup injury human body, muscle, tendon and vessel, skeleton and internal organs, gently Integumentary musculature swelling and pain due to blood stasis, bleeding or injury of tendon and muscle fracture then can be caused, dislocation；Heavy then damage internal organs, or Massive Bleeding, lead to dusk The serious change such as fan, tic, YANG-depletion.Traumatic injury causes muscle flesh bone damage, then leads to meridians to hinder, and coagulation of QI-blood produces Raw blood stasis, symptom is local swelling, pain, ecchymosis, limb activity are limited etc..
Content of the invention
It is an object of the invention in place of overcoming the deficiencies in the prior art, there is provided a kind of medicine for treating traumatic injury Compositions and preparation method thereof, this pharmaceutical composition energy blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, expelling wind and removing dampness, liver and kidney tonifying, strong muscle Bone, has preferable curative effect to diseases such as various traumatic injury, rheumatic ostalgia, lumbago and backache.
One of the technical solution adopted for the present invention to solve the technical problems is:
A kind of pharmaceutical composition for treating traumatic injury, the crude drug of described pharmaceutical composition according to the mass fraction, Including: 30～34 parts of Herba Artemisiae Anomalae, 18～22 parts of Rhizoma Dioscoreae Nipponicae, 30～34 parts of Cortex Acanthopanciss, 30～34 parts of Lignum Sappan, 4～6 parts of Radix Aconiti, grass 4～6 parts of crow, 4～6 parts of kwan-yin lotus throne Herba pteridii latiusculi, 32～38 parts of Rhizoma Drynariae, 4～6 parts of Radix Angelicae Sinensis, 18～22 parts of the Radix Angelicae Dahuricae, 9～11 parts of Rhizoma Chuanxiong, 9～11 parts of Radix Stephaniae Tetrandrae, 4～6 parts of Rhizoma amorphophalli, 14～16 parts of Olibanum, 14～16 parts of Myrrha, 32～38 parts of Flos Carthami, 32～38 parts of Fructus Aurantii Immaturus, wood Fragrant 28～32 parts, 26～30 parts of capsule compatriot, 28～32 parts of Fructus Gardeniae, 28～32 parts of Pyritum, 30～34 parts of Semen Sinapis Albae, Rhizoma seu Herba Elatostematis stewardii 26～30 parts, 18～22 parts of Radix Fici Simplicissimae, 4～6 parts of Herba speranskiae tuberculatae, 30～34 parts of Concha Meretricis Seu Cyclinae, 26～30 parts of Camphora, Radix Angelicae Sinensis 28～32 Part, 32～38 parts of Radix Et Rhizoma Rhei, 28～32 parts of Borneolum Syntheticum, 28～32 parts of Radix Dipsaci, 26～30 parts of Rhizoma Atractylodis, 32～38 parts of Radix Notoginseng, Ramulus Cinnamomi 32～ 38 parts, 26～30 parts of Radix Achyranthis Bidentatae, 9～11 parts of Lignum Pini Nodi, sign 9～11 parts of grass, and 3500～4500 parts of 50～60% ethanol.
In one embodiment: the crude drug of described pharmaceutical composition is according to the mass fraction, comprising: 32 parts of Herba Artemisiae Anomalae, Rhizoma Dioscoreae Nipponicae 20 parts, 32 parts of Cortex Acanthopanciss, 32 parts of Lignum Sappan, 5 parts of Radix Aconiti, 5 parts of Radix Aconiti Kusnezoffii, 5 parts of kwan-yin lotus throne Herba pteridii latiusculi, 35 parts of Rhizoma Drynariae, 5 parts of Radix Angelicae Sinensis, in vain 20 parts of the root of Dahurian angelica, 10 parts of Rhizoma Chuanxiong, 10 parts of Radix Stephaniae Tetrandrae, 5 parts of Rhizoma amorphophalli, 15 parts of Olibanum, 15 parts of Myrrha, 35 parts of Flos Carthami, 35 parts of Fructus Aurantii Immaturus, the Radix Aucklandiae 30 Part, 28 parts of capsule compatriot, 30 parts of Fructus Gardeniae, 30 parts of Pyritum, 32 parts of Semen Sinapis Albae, 28 parts of Rhizoma seu Herba Elatostematis stewardii, 20 parts of Radix Fici Simplicissimae is deep 5 parts of grass, 32 parts of Concha Meretricis Seu Cyclinae, 28 parts of Camphora, 30 parts of Radix Angelicae Sinensis, 35 parts of Radix Et Rhizoma Rhei, 30 parts of Borneolum Syntheticum, 30 parts of Radix Dipsaci, 28 parts of Rhizoma Atractylodis, Radix Notoginseng 35 Part, 35 parts of Ramulus Cinnamomi, 28 parts of Radix Achyranthis Bidentatae, 10 parts of Lignum Pini Nodi, sign 10 parts of grass, and 4000 parts of 56% ethanol.
In one embodiment: described 50～60% ethanol are 50～60 degree of Chinese liquor.
The two of the technical solution adopted for the present invention to solve the technical problems are:
A kind of preparation method of aforementioned pharmaceutical compositions, removes Borneolum Syntheticum, each crude drug outside Chinese liquor, after pulverizing, adds ice Piece, mix homogeneously, add in described Chinese liquor, soak 3～5 months, obtain final product medicated wine；Smear external.
In one embodiment: remove Borneolum Syntheticum, each crude drug outside ethanol, after pulverizing, add Borneolum Syntheticum, mix homogeneously, add institute State in ethanol and extracted with percolation, obtain final product tincture；Smear external.
In one embodiment: remove Camphora, Borneolum Syntheticum, each crude drug outside ethanol, after pulverizing, mix homogeneously, add described second Extract in alcohol, lixiviating solution concentrates and extractum is obtained, and after extractum is mixed with Camphora, Borneolum Syntheticum, adds to conventional paste substrate, is coated In conventional backing layer, obtain final product unguentum；Stick external.
In one embodiment: remove Camphora, Borneolum Syntheticum, each crude drug outside ethanol, after pulverizing, mix homogeneously, add described second Extract in alcohol, lixiviating solution concentrates and fluid extract is obtained, Camphora, Borneolum Syntheticum are dissolved in adding in fluid extract after a small amount of ethanol and mix, obtains final product Paste；Smear external.
In one embodiment: remove Camphora, Borneolum Syntheticum, each crude drug outside ethanol, after pulverizing, mix homogeneously, add described second Extract in alcohol, lixiviating solution concentrates and extractum is obtained, and after extractum is mixed with Camphora, Borneolum Syntheticum, dries, is ground into fine powder, obtains final product powder；Apply Smear external.
Compared with background technology, it has the advantage that the technical program
Traumatic injury causes muscle flesh bone damage by external force, then leads to meridians to hinder, and coagulation of QI-blood produces blood stasis.Office Portion's blood stasis, thrombosis cause the stagnation of QI again.The stagnation of QI increases blood stasis, and blood stasis increases the stagnation of QI again, and both vicious cycle lead to QI and blood not Logical, stagnation of QI and blood may bring about pain.It is not smooth that the stagnation of QI can cause body fluid to run again, and water is wet cohesion, causes the pathological states such as phlegm retention, leads to patient's condition touching Difficulty heals.In the pharmaceutical composition of the present invention, Herba Artemisiae Anomalae blood-activating analgetic, hemostasis are cured the wound, Lignum Sappan invigorating circulation of blood to dissipate blood stasis and reducing swelling and relieving pain, osteomiosis Mend promoting the circulation of blood arteries and veins, reuniting the fractured tendons and bones, pain relieving of curing the wound, Flos Carthami promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, Pyritum eliminating stasis to stop pain, synthetism are cured the wound, Radix Angelicae Sinensis are lived Blood, Chinese angelica blood supplementing, with using blood circulation promoting and enriching pain relieving, Radix Et Rhizoma Rhei hemostasis is detoxified, blood circulation promoting and blood stasis dispelling, Radix Notoginseng removing stasis to stop bleeding, promoting blood circulation for Radix Angelicae Sinensis, Radix Angelicae Sinensis Analgesic therapy, Radix Achyranthis Bidentatae is apt to descending, promoting blood circulation to restore menstrual flow, and muscle promoting blood circulation is stretched in Olibanum circulation of qi promoting, and Myrrha dissipates blood blood stasis dispelling, and Olibanum, Myrrha mutual reinforcement between are use, a surname Logical the bottom of heart, promoting flow of QI and blood, disperse blood stasis and dredge collateral, above all medicines play blood circulation promoting and blood stasis dispelling, the effect of symplectic bone of curing the wound altogether；Then removed with Rhizoma Dioscoreae Nipponicae wind-dispelling Wet, promoting blood circulation to remove obstruction in the collateral, Cortex Acanthopanciss wind-damp dispelling, the meridian dredging, the bitter fall of the pungent row of Fructus Aurantii Immaturus, dispelling the stagnated QI intestinal stasis relieving, Radix Aucklandiae promoting the circulation of QI to relieve pain, compatriot, synthetism Careless damp eliminating restores menstrual flow and invigorates blood circulation, Fructus Gardeniae clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, reducing swelling and alleviating pain, and Semen Sinapis Albae can be dispelled the expectorant of meridians, and can Sweeling-eliminating medicine powder Knot, removing obstruction in the collateral to relieve pain, Herba speranskiae tuberculatae expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, the pungent scattered hardship of Rhizoma Atractylodis is dry, drying damp and strengthening spleen, and Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, cold expelling stop Bitterly, the sensible pain relieving of the Radix Angelicae Dahuricae, Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Radix Stephaniae Tetrandrae expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, the bitter dry temperature of Lignum Pini Nodi is led to, is stimulated the menstrual flow Pain relieving, especially kind wind-cold damp pathogen between muscles and bones of dispelling, Herba Siegesbeckiae wind-damp dispelling, sharp joint, Rhizoma amorphophalli blood circulation promoting and blood stasis dispelling, removing toxic substances and promoting subsidence of swelling, Radix Aconiti wind-dispelling Dehumidifying, dispersing cold for relieving pain, Radix Aconiti Kusnezoffii expelling wind and removing dampness, antalgic, kwan-yin lotus throne Herba pteridii latiusculi dispelling wind is dispelled silt, and above all taste medicine promoting of the circulation of QI and removing the obstruction in the collaterals are dispelled Wind dehumidifies, cold expelling reducing swelling and alleviating pain；Separately plus Radix Fici Simplicissimae QI invigorating qi-restoratives, promoting QI circulation for relieving depression, strong muscle are active, Radix Dipsaci invigorating the liver and kidney, strong muscle Bone, continuous folding of curing the wound, cooperation Rhizoma Drynariae, Radix Achyranthis Bidentatae, concurrence invigorating the liver and kidney, bone and muscle strengthening, the effect of QI invigorating qi-restoratives；With wine promoting blood circulation, help medicine gesture, Draw all medicines to go directly disease institute, with blood circulation promoting and blood stasis dispelling, dredging the meridian be will, then liver and kidney tonifying, dehumidifying spleen invigorating, adjust that to reach qi-blood-body fluid logical Freely；It is aided with Concha Meretricis Seu Cyclinae removing dampness sore, Camphora dehumidifying parasite killing, warming and odynolysis, Borneolum Syntheticum clearing away heat to alleviate pain, erosion prevention and muscle growing again, promote affected part to heal Close.All medicines enable altogether so that the pharmaceutical composition blood circulation promoting and blood stasis dispelling of the present invention, removing obstruction in the collateral to relieve pain, expelling wind and removing dampness, liver and kidney tonifying, strong Muscle reinforcing and bone strengthening, has preferable curative effect to diseases such as various traumatic injury, rheumatic ostalgia.
Specific embodiment
Illustrate present disclosure below by embodiment:
Embodiment 1
Herba Artemisiae Anomalae 32g, Rhizoma Dioscoreae Nipponicae 20g, Cortex Acanthopanciss 32g, Lignum Sappan 32g, Radix Aconiti 5g, Radix Aconiti Kusnezoffii 5g, kwan-yin lotus throne Herba pteridii latiusculi 5g, osteomiosis Mend 35g, Radix Angelicae Sinensis 5g, Radix Angelicae Dahuricae 20g, Rhizoma Chuanxiong 10g, Radix Stephaniae Tetrandrae 10g, Rhizoma amorphophalli 5g, Olibanum 15g, Myrrha 15g, Flos Carthami 35g, Fructus Aurantii Immaturus 35g, Radix Aucklandiae 30g, capsule compatriot 28g, Fructus Gardeniae 30g, Pyritum 30g, Semen Sinapis Albae 32g, Rhizoma seu Herba Elatostematis stewardii 28g, Radix Fici Simplicissimae 20g are deep Careless 5g, Concha Meretricis Seu Cyclinae 32g, Camphora 28g, Radix Angelicae Sinensis 30g, Radix Et Rhizoma Rhei 35g, Borneolum Syntheticum 30g, Radix Dipsaci 30g, Rhizoma Atractylodis 28g, Radix Notoginseng 35g, Ramulus Cinnamomi 35g, Radix Achyranthis Bidentatae 28g, Lignum Pini Nodi 10g, sign careless 10g.
After taking above-mentioned medical material (in addition to Borneolum Syntheticum) pulverizing, add Borneolum Syntheticum, mix homogeneously, add in 56 degree of Chinese liquor 4000g, soak 3～5 months, obtain final product medicated wine；Smear external.
Embodiment 2
Herba Artemisiae Anomalae 30g, Rhizoma Dioscoreae Nipponicae 18g, Cortex Acanthopanciss 34g, Lignum Sappan 30g, Radix Aconiti 6g, Radix Aconiti Kusnezoffii 6g, kwan-yin lotus throne Herba pteridii latiusculi 4g, osteomiosis Mend 33g, Radix Angelicae Sinensis 6g, Radix Angelicae Dahuricae 22g, Rhizoma Chuanxiong 9g, Radix Stephaniae Tetrandrae 11g, Rhizoma amorphophalli 4g, Olibanum 14g, Myrrha 14g, Flos Carthami 37g, Fructus Aurantii Immaturus 37g, wood Fragrant 32g, capsule compatriot 26g, Fructus Gardeniae 28g, Pyritum 32g, Semen Sinapis Albae 30g, Rhizoma seu Herba Elatostematis stewardii 26g, Radix Fici Simplicissimae 18g, Herba speranskiae tuberculatae 6g, Concha Meretricis Seu Cyclinae 30g, Camphora 30g, Radix Angelicae Sinensis 32g, Radix Et Rhizoma Rhei 32g, Borneolum Syntheticum 28g, Radix Dipsaci 32g, Rhizoma Atractylodis 30g, Radix Notoginseng 37g, Ramulus Cinnamomi 32g, cattle Knee joint 26g, Lignum Pini Nodi 11g, sign careless 9g.
After taking above-mentioned medical material (in addition to Borneolum Syntheticum) pulverizing, add Borneolum Syntheticum, mix homogeneously, add in 50% ethanol 4500g, to ooze Method of filtering is extracted, and obtains final product tincture；Smear external.
Embodiment 3
Herba Artemisiae Anomalae 32g, Rhizoma Dioscoreae Nipponicae 20g, Cortex Acanthopanciss 32g, Lignum Sappan 32g, Radix Aconiti 5g, Radix Aconiti Kusnezoffii 5g, kwan-yin lotus throne Herba pteridii latiusculi 5g, osteomiosis Mend 35g, Radix Angelicae Sinensis 5g, Radix Angelicae Dahuricae 20g, Rhizoma Chuanxiong 10g, Radix Stephaniae Tetrandrae 10g, Rhizoma amorphophalli 5g, Olibanum 15g, Myrrha 15g, Flos Carthami 35g, Fructus Aurantii Immaturus 35g, Radix Aucklandiae 30g, capsule compatriot 28g, Fructus Gardeniae 30g, Pyritum 30g, Semen Sinapis Albae 32g, Rhizoma seu Herba Elatostematis stewardii 28g, Radix Fici Simplicissimae 20g are deep Careless 5g, Concha Meretricis Seu Cyclinae 32g, Camphora 28g, Radix Angelicae Sinensis 30g, Radix Et Rhizoma Rhei 35g, Borneolum Syntheticum 30g, Radix Dipsaci 30g, Rhizoma Atractylodis 28g, Radix Notoginseng 35g, Ramulus Cinnamomi 35g, Radix Achyranthis Bidentatae 28g, Lignum Pini Nodi 10g, sign careless 10g.
After taking above-mentioned medical material (in addition to Camphora, Borneolum Syntheticum) pulverizing, mix homogeneously, add in 56% ethanol 4000g and extract, extraction Liquid concentrates and extractum is obtained, and after extractum is mixed with Camphora, Borneolum Syntheticum, adds to conventional paste substrate, repastes and be distributed in conventional backing layer, Obtain final product unguentum；Stick external.
Described routine paste substrate such as rubber, and for example adhesive Colophonium, sodium alginate, gelatin etc., the poly- second of wetting agent two Alcohol, propylene glycol etc., filler zinc oxide, micropowder silica gel, titanium dioxide etc., softening agent vaseline, lanoline etc., penetration enhancer Azone etc.；Described routine backing layer such as fine cloth, non-woven fabrics, composite film material etc..
Embodiment 4
Herba Artemisiae Anomalae 34g, Rhizoma Dioscoreae Nipponicae 22g, Cortex Acanthopanciss 30g, Lignum Sappan 34g, Radix Aconiti 4g, Radix Aconiti Kusnezoffii 4g, kwan-yin lotus throne Herba pteridii latiusculi 6g, osteomiosis Mend 37g, Radix Angelicae Sinensis 4g, Radix Angelicae Dahuricae 18g, Rhizoma Chuanxiong 11g, Radix Stephaniae Tetrandrae 9g, Rhizoma amorphophalli 6g, Olibanum 16g, Myrrha 16g, Flos Carthami 32g, Fructus Aurantii Immaturus 32g, wood Fragrant 28g, capsule compatriot 30g, Fructus Gardeniae 32g, Pyritum 28g, Semen Sinapis Albae 34g, Rhizoma seu Herba Elatostematis stewardii 30g, Radix Fici Simplicissimae 22g, Herba speranskiae tuberculatae 4g, Concha Meretricis Seu Cyclinae 34g, Camphora 26g, Radix Angelicae Sinensis 28g, Radix Et Rhizoma Rhei 37g, Borneolum Syntheticum 32g, Radix Dipsaci 28g, Rhizoma Atractylodis 26g, Radix Notoginseng 32g, Ramulus Cinnamomi 37g, cattle Knee joint 30g, Lignum Pini Nodi 9g, sign careless 11g.
After taking above-mentioned medical material (in addition to Camphora, Borneolum Syntheticum) pulverizing, mix homogeneously, add in 60% ethanol 3500g and extract, extraction Liquid concentrates and fluid extract is obtained, and Camphora, Borneolum Syntheticum is dissolved in adding in fluid extract after a small amount of ethanol and mixes, obtains final product paste；Smear external.
Embodiment 5
Herba Artemisiae Anomalae 32g, Rhizoma Dioscoreae Nipponicae 20g, Cortex Acanthopanciss 32g, Lignum Sappan 32g, Radix Aconiti 5g, Radix Aconiti Kusnezoffii 5g, kwan-yin lotus throne Herba pteridii latiusculi 5g, osteomiosis Mend 35g, Radix Angelicae Sinensis 5g, Radix Angelicae Dahuricae 20g, Rhizoma Chuanxiong 10g, Radix Stephaniae Tetrandrae 10g, Rhizoma amorphophalli 5g, Olibanum 15g, Myrrha 15g, Flos Carthami 35g, Fructus Aurantii Immaturus 35g, Radix Aucklandiae 30g, capsule compatriot 28g, Fructus Gardeniae 30g, Pyritum 30g, Semen Sinapis Albae 32g, Rhizoma seu Herba Elatostematis stewardii 28g, Radix Fici Simplicissimae 20g are deep Careless 5g, Concha Meretricis Seu Cyclinae 32g, Camphora 28g, Radix Angelicae Sinensis 30g, Radix Et Rhizoma Rhei 35g, Borneolum Syntheticum 30g, Radix Dipsaci 30g, Rhizoma Atractylodis 28g, Radix Notoginseng 35g, Ramulus Cinnamomi 35g, Radix Achyranthis Bidentatae 28g, Lignum Pini Nodi 10g, sign careless 10g.
After taking above-mentioned medical material (in addition to Camphora, Borneolum Syntheticum) pulverizing, mix homogeneously, add in 56% ethanol 4000g and extract, extraction Liquid concentrates and extractum is obtained, and after extractum is mixed with Camphora, Borneolum Syntheticum, dries, is ground into fine powder, obtains final product powder；Smear external.
Experimental example 1
Patient 1, king so-and-so, man, 50 years old, suffer from pain in the lumbar region 5 years, after diagnosing for prolapse of lumbar intervertebral disc, treatment effect is undesirable.Using After the medicated wine of the embodiment of the present invention 1 smears three, symptom substantially mitigates；Adhere to smearing the remaining recovery from illness of the moon.Follow-up is not recurred for 1 year.
Experimental example 2
Patient 2, Lee so-and-so, female, 35 years old, from puerperal fall pain in the lumbar region disease.Unguentum using the embodiment of the present invention 3 pastes, and three Symptom is relieved in the future, and after January, symptom disappears.
Experimental example 3
Patient 3, Zhang, female, 27 years old, and leg imprudence bumps against table angle, and livid purple ecchymosis does not disappear for many days.Real using the present invention The powder applying example 5 is spread on affected part and smears, and after five days, ecchymosis disappears.
Experimental example 4
Patient 4, Cui so-and-so, female, 46 years old, suffer from rheumatic ostalgia for many years, a change of weather is knee pain.The present invention is adopted during outbreak The medicated wine of embodiment 1 is smeared, and aches Ketorolac.After adhering to smearing more than the moon, then have no that rheumatism is shown effect.
Experimental example 5
Patient 5, Chen, man, 19 years old it is not intended in get injured by a fall, knee, ancon are livid purple.Unguentum patch using the embodiment of the present invention 3 Fully recover after covering five.
Experimental example 6
Patient 6, week certain, man, 54 years old, suffer from rheumatic ostalgia for many years.Medicated wine using the embodiment of the present invention 1 is smeared daily, hard Hold symptom mitigation after first quarter moon, fully recover after March, follow-up half a year does not recur.
Experimental example 7
Patient 7, in certain, male, 76 years old, suffer from lumbago and skelalgia more than two decades, and life is rough to take care of oneself.Treatment effect is inconspicuous.Using After the tincture of the embodiment of the present invention 2 smears two months, life can be taken care of oneself substantially, adheres to fully recovering using after March.Follow-up has no for 2 years Recurrence.
Experimental example 8
Patient 8, Zhang, man, 7 years old, get injured by a fall many days, knee livid purple ecchymosis difficulty disappears.Medicine using the embodiment of the present invention 1 Wine is smeared, and after three days, congestive edema disappears substantially.
Experimental example 9
Patient 9, Lee so-and-so, female, 63 years old, suffer from more than ten years of pain in the lumbar region, market bought medicine is taken and external is invalid by oneself.Using this The tincture of inventive embodiments 2 improves after smearing first quarter moon, fully recovers after adhering to smearing March.Follow-up half a year does not recur.
Experimental example 10
Patient 10, Wu, man, and 25 years old, during running, knee was sprained.Smeared after two days using the paste of the embodiment of the present invention 4 Recover.
The above, only present pre-ferred embodiments, therefore can not limit according to this present invention enforcement scope, that is, according to Equivalence changes and modification that the scope of the claims of the present invention and description are made, all should still belong in the range of the present invention covers.

Claims (8)

1. a kind of pharmaceutical composition for treating traumatic injury it is characterised in that: the crude drug of described pharmaceutical composition is by matter Amount number meter, comprising: 30～34 parts of Herba Artemisiae Anomalae, 18～22 parts of Rhizoma Dioscoreae Nipponicae, 30～34 parts of Cortex Acanthopanciss, 30～34 parts of Lignum Sappan, Radix Aconiti 4 ～6 parts, 4～6 parts of Radix Aconiti Kusnezoffii, 4～6 parts of kwan-yin lotus throne Herba pteridii latiusculi, 32～38 parts of Rhizoma Drynariae, 4～6 parts of Radix Angelicae Sinensis, 18～22 parts of the Radix Angelicae Dahuricae, Rhizoma Chuanxiong 9～11 parts, 9～11 parts of Radix Stephaniae Tetrandrae, 4～6 parts of Rhizoma amorphophalli, 14～16 parts of Olibanum, 14～16 parts of Myrrha, 32～38 parts of Flos Carthami, Fructus Aurantii Immaturus 32 ～38 parts, 28～32 parts of the Radix Aucklandiae, 26～30 parts of capsule compatriot, 28～32 parts of Fructus Gardeniae, 28～32 parts of Pyritum, Semen Sinapis Albae 30～34 Part, 26～30 parts of Rhizoma seu Herba Elatostematis stewardii, 18～22 parts of Radix Fici Simplicissimae, 4～6 parts of Herba speranskiae tuberculatae, 30～34 parts of Concha Meretricis Seu Cyclinae, 26～30 parts of Camphora, 28～32 parts of Radix Angelicae Sinensis, 32～38 parts of Radix Et Rhizoma Rhei, 28～32 parts of Borneolum Syntheticum, 28～32 parts of Radix Dipsaci, 26～30 parts of Rhizoma Atractylodis, Radix Notoginseng 32～38 Part, 32～38 parts of Ramulus Cinnamomi, 26～30 parts of Radix Achyranthis Bidentatae, 9～11 parts of Lignum Pini Nodi, sign 9～11 parts of grass, and 50～60% ethanol 3500～ 4500 parts.
2. the pharmaceutical composition for treating traumatic injury according to claim 1 it is characterised in that: described drug regimen The crude drug of thing is according to the mass fraction, comprising: 32 parts of Herba Artemisiae Anomalae, 20 parts of Rhizoma Dioscoreae Nipponicae, 32 parts of Cortex Acanthopanciss, 32 parts of Lignum Sappan, Radix Aconiti 5 Part, 5 parts of Radix Aconiti Kusnezoffii, 5 parts of kwan-yin lotus throne Herba pteridii latiusculi, 35 parts of Rhizoma Drynariae, 5 parts of Radix Angelicae Sinensis, 20 parts of the Radix Angelicae Dahuricae, 10 parts of Rhizoma Chuanxiong, 10 parts of Radix Stephaniae Tetrandrae, Rhizoma amorphophalli 5 Part, 15 parts of Olibanum, 15 parts of Myrrha, 35 parts of Flos Carthami, 35 parts of Fructus Aurantii Immaturus, 30 parts of the Radix Aucklandiae, 28 parts of capsule compatriot, 30 parts of Fructus Gardeniae, Pyritum 30 parts, 32 parts of Semen Sinapis Albae, 28 parts of Rhizoma seu Herba Elatostematis stewardii, 20 parts of Radix Fici Simplicissimae, 5 parts of Herba speranskiae tuberculatae, 32 parts of Concha Meretricis Seu Cyclinae, 28 parts of Camphora, Radix Angelicae Sinensis 30 Part, 35 parts of Radix Et Rhizoma Rhei, 30 parts of Borneolum Syntheticum, 30 parts of Radix Dipsaci, 28 parts of Rhizoma Atractylodis, 35 parts of Radix Notoginseng, 35 parts of Ramulus Cinnamomi, 28 parts of Radix Achyranthis Bidentatae, 10 parts of Lignum Pini Nodi, Sign 10 parts of grass, and 4000 parts of 56% ethanol.
3. the pharmaceutical composition for treating traumatic injury according to claim 1 it is characterised in that: described 50～60% Ethanol is 50～60 degree of Chinese liquor.
4. the pharmaceutical composition described in a kind of claim 3 preparation method it is characterised in that: remove Borneolum Syntheticum, each outside Chinese liquor Crude drug, after pulverizing, adds Borneolum Syntheticum, mix homogeneously, adds in described Chinese liquor, soak 3～5 months, obtain final product medicated wine；Smear outer With.
5. the pharmaceutical composition any one of a kind of claims 1 to 3 preparation method it is characterised in that: remove Borneolum Syntheticum, Each crude drug outside ethanol, after pulverizing, is added Borneolum Syntheticum, mix homogeneously, adds in described ethanol and extracted with percolation, obtain final product tincture Agent；Smear external.
6. the pharmaceutical composition any one of a kind of claims 1 to 3 preparation method it is characterised in that: remove Camphora, Each crude drug outside Borneolum Syntheticum, ethanol, after pulverizing, mix homogeneously, add in described ethanol and extract, lixiviating solution concentrates and extractum is obtained, After extractum is mixed with Camphora, Borneolum Syntheticum, add to conventional paste substrate, repaste and be distributed in conventional backing layer, obtain final product unguentum；Stick outer With.
7. the pharmaceutical composition any one of a kind of claims 1 to 3 preparation method it is characterised in that: remove Camphora, Each crude drug outside Borneolum Syntheticum, ethanol, after pulverizing, mix homogeneously, add in described ethanol and extract, lixiviating solution concentrates and stream leaching is obtained Cream, Camphora, Borneolum Syntheticum is dissolved in adding in fluid extract after a small amount of ethanol and mixes, obtains final product paste；Smear external.
8. the pharmaceutical composition any one of a kind of claims 1 to 3 preparation method it is characterised in that: remove Camphora, Each crude drug outside Borneolum Syntheticum, ethanol, after pulverizing, mix homogeneously, add in described ethanol and extract, lixiviating solution concentrates and extractum is obtained, After extractum is mixed with Camphora, Borneolum Syntheticum, dry, be ground into fine powder, obtain final product powder；Smear external.
CN201610638502.6A 2016-08-05 2016-08-05 Pharmaceutical composition for treating traumatic injuries and preparation method thereof Pending CN106334061A (en)

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CN1240663A (en) * 1999-06-28 2000-01-12 高福安 Plaster for treating trauma, bone fracture and rheumatism and its preparing process
CN102988657A (en) * 2012-11-26 2013-03-27 高彦龙 Plaster for treating fracture and traumatic injury and preparation method of plaster
CN103566313A (en) * 2013-11-27 2014-02-12 陈燕 External-application medicine for treating traumatic injuries
CN103961620A (en) * 2014-05-28 2014-08-06 孟伟 External traditional Chinese medicine for treating limb fractures and preparation method thereof
CN105106447A (en) * 2015-09-29 2015-12-02 镇远县道益堂生物科技有限公司 Osteoproliferation, osteoarticular diseases and traumatic injury treatment plaster

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1240663A (en) * 1999-06-28 2000-01-12 高福安 Plaster for treating trauma, bone fracture and rheumatism and its preparing process
CN102988657A (en) * 2012-11-26 2013-03-27 高彦龙 Plaster for treating fracture and traumatic injury and preparation method of plaster
CN103566313A (en) * 2013-11-27 2014-02-12 陈燕 External-application medicine for treating traumatic injuries
CN103961620A (en) * 2014-05-28 2014-08-06 孟伟 External traditional Chinese medicine for treating limb fractures and preparation method thereof
CN105106447A (en) * 2015-09-29 2015-12-02 镇远县道益堂生物科技有限公司 Osteoproliferation, osteoarticular diseases and traumatic injury treatment plaster

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