CN106310042A - Medicine stone prepared from traditional Chinese medicine dregs and preparation method thereof - Google Patents

Medicine stone prepared from traditional Chinese medicine dregs and preparation method thereof Download PDF

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Publication number
CN106310042A
CN106310042A CN201610848719.XA CN201610848719A CN106310042A CN 106310042 A CN106310042 A CN 106310042A CN 201610848719 A CN201610848719 A CN 201610848719A CN 106310042 A CN106310042 A CN 106310042A
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chinese medicine
yaoshi
medicine dreg
prepared
preparation
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陈华丰
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Guangzhou Shishi Weng Biotechnology Co Ltd
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Guangzhou Shishi Weng Biotechnology Co Ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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Abstract

The invention relates to medicine stone prepared by traditional Chinese medicine dregs and a preparation method thereof. The traditional Chinese medicine stone is prepared from the following raw materials in percentage by weight: 8 to 11 parts of traditional Chinese medicine dregs, 0.001 to 0.01 part of saccharomyces cerevisiae, 0.0003 to 0.0015 part of safflowers, 0.0003 to 0.0015 part of rhizoma cyperi, 0.01 to 0.1 part of Chinese yam, 0 to 0.02 part of preservatives. The preparation method of the medicine stone comprises the following steps that the traditional Chinese medicine dregs are sterilized, fermented, dried and smashed; then, other raw materials are uniformly stirred; next, press molding formation and drying are performed; the medicine stone is obtained. Diseases treated by the medicine stone are identical to the diseases treated by corresponding medicine materials. After the traditional Chinese medicine dregs are prepared into the medicine stone by the method, the environment problem caused by direct discharging of traditional Chinese medicine dregs is solved; in addition, the active ingredients in the traditional Chinese medicine dregs are used and improved to the greatest degree; the rest medicine effect is excited; when the medicine stone is used for treating corresponding diseases, the effect is obvious.

Description

YAOSHI prepared with Chinese medicine dreg and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, particularly relate to YAOSHI prepared by a kind of Chinese medicine dreg and preparation method thereof.
Background technology
Chinese medicine dreg occurs mainly with Chinese patent medicine, Chinese crude drug, crude drug etc., the main Chinese patent medicine that is derived from, and accounts for Chinese medicine The 70% of medicinal residues sum.Owing to Chinese medicine dreg is generally wet stock, easily addle, especially even more serious in summer, therefore, Chinese medicine Medicinal residues are also one of polluter the most serious in Chinese medicine enterprise.Due to Chinese medicinal material and produce numerous in variety, the medicinal residues of generation are also Varied, these factors are all given to process further and are brought difficulty, so most enterprises is all directly to arrange as refuse Put, bring more serious pollution to surrounding enviroment.Along with the increasing of Environmental management is with " country's pharmaceutical industry is strong Discharge standard processed " will put into effect, Chinese medicine dreg directly discharges and will be governed, how to carry out Chinese medicine dreg process and again profit With, it is pendulum problem in face of each Chinese medicine enterprise and researcher.
Rich in there being the compositions such as Organic substance and trace element such as fiber, polysaccharide, albumen inside Chinese medicine dreg, and, Chinese medicine Material is after extracting its main component, and remaining medicinal residues still contain a large amount of active component.After measured, pharmacopeia side HUOXIANG ZHENGQI SHUI Medicinal residues have the various trace elements such as crude fibre 24%, crude fat 1%, crude protein 2%, crude polysaccharides 8%, and calcium, phosphorus, ferrum; Containing total polysaccharides 18% in the Fructus Lycii pharmacy medicinal residues of Jilin, galacturonic acid 7%, ten several aminoacid and trace element;With 60% Ethanol Radix Ginseng is extracted after, measure its medicinal residues being dried, find every 100g still contains Radix Ginseng total saponins 196mg, ten Several amino acids, the trace element of the most multiple needed by human body;Liposoluble in Radix Salviae Miltiorrhizae decoction dregs is extracted by percolation and circumfluence method Property composition time, measure tanshinone IIA content be up to 3.216mg/g;Use the Radix Astragali flavone in the ethanol extraction Radix Astragali and Saponin, Then utilizing gained medicinal residues water extraction astragalus polysaccharides, astragalus polysaccharides yield is 12.93%, high purity 93.27%;Yellow Asia and Africa Deng by the main constituent Radix Astragali first of astragaloside in the Milkvetch Root of the same producer of high effective liquid chromatography for measuring and astragalus root dregs The content of glycosides, contrast finds, in astragalus root dregs, the extracted amount of astragaloside is the 72.08% of Milkvetch Root, yellow in Radix Scutellariae medicinal residues The content of a kind of reed mentioned in ancient books glycosides is the 70.3% of radix scutellariae medicinal materials total content;Flavones content in Herba Epimedii medicinal residues is flavones content in former medicine 39.64% (in former medicine flavones content 122.89 μ g/mL, in medicinal residues, flavones content reaches 34.00 μ g/mL).
From the point of view of data above, Chinese medicine dreg using value is higher, and for many years, some enterprises carried out Chinese medicine dreg again The trial utilized, also achieves some effects.In early days, China's Chinese crude drug intensive manufacture, Chinese medicine dreg recycle aspect master Poultry to be concentrated on, cattle breeding field, after feeding chicken, pig, fish, or compost such as Chinese medicine dreg as feedstuff or feed additive For planting vegetable etc..In recent years, the following aspects is expanded in Chinese medicine dreg reutilization technology direction to: extract other more effective Composition, for culturing edible fungus, as feedstuff or feed additive, make organic fertilizer etc..Extract other effective ingredient again to deposit In following deficiency: extractive technique difficulty is big the most again, extraction is the highest, high cost;2. the Chinese medicine slag source extracted needs list One, the medicinal residues of single Chinese medicine kind just can extract, and the produced Chinese medicine of the current substantial amounts of pharmaceutical factory of traditional Chinese medicine mostly is compound, generation Medicinal residues mostly also are the compound prescription medicinal residues for the treatment of different syndromes, it is impossible to utilize extractive technique again;3. after extracting, its Chinese medicine slag is still Existing, and extraction method will not make Chinese medicine slag decrement, every composition of remaining medicinal residues reduces further, make follow-up disposal be more difficult to into OK.For culturing edible fungus and make organic fertilizer and have the disadvantage that in Chinese medicine slag, remaining effective ingredient is still the highest , such as flavone, tanshinone IIA, astragaloside etc., for culturing edible fungus or prepare fertilizer, it is only that these are the most effective Composition has also served as organic nutrient substance etc. and has been processed, although be recycling, but surcharge is low, belongs to resource profit Low extreme direction.A residual huge sum of money in part Chinese medicine slag is had the disadvantage that as the feedstuff such as domestic animal, poultry or feed additive Belonging to composition, it is impossible to enter food chain, some Chinese medicine slag can bring food safety hidden danger for feed additive.Visible above profit again Technology all also exist that recycling scope is little, conceptual phase is primary, the deficiency such as the added value of recycling is low.
Aforementioned data shows, still suffers from a large amount of active component in Chinese medicine dreg, can continue to use as raw material of Chinese medicine, The surplus value highest part of Chinese medicine dreg should be residual effective ingredient, should from play residue drug effect from the point of view of Chinese medicines The recycling of slag, can reach high added value, the target of the high-end utilization of resources.
Summary of the invention
Based on this, the invention provides YAOSHI prepared by a kind of Chinese medicine dreg, this YAOSHI can utilize to greatest extent Effective ingredient in medicinal residues, inspires residue drug effect, can be used for treating corresponding disease, and the disease of its treatment is treated with corresponding medical material Disease identical.
Concrete technical scheme is as follows:
YAOSHI prepared by a kind of Chinese medicine dreg, is prepared from by the raw material of following percentage by weight:
Wherein in some embodiments, YAOSHI prepared by described Chinese medicine dreg is prepared by the raw material of following percentage by weight Form:
Wherein in some embodiments, described Chinese medicine dreg is Chinese medicine dreg or the Chinese medicine of the solid gold plaque of Bulbus Lilii of SHIDUQING PIAN Medicinal residues.
Wherein in some embodiments, described Flos Carthami be particle diameter be the saffron powder of 100nm-120nm, described Rhizoma Cyperi is grain Footpath is the Nutgrass Galingale Rhizome of 100nm-120nm, described Rhizoma Dioscoreae be particle diameter be the Rhizoma Dioscoreae powder of 100nm-120nm.
Wherein in some embodiments, described preservative is at least one in poly-D-lysine and tea polyphenols.
Present invention also offers a kind of method that Chinese medicine dreg prepares YAOSHI, the YAOSHI prepared by the method is permissible Utilize the effective ingredient in medicinal residues to greatest extent, inspire residue drug effect, can be used for treating corresponding disease, the disease of its treatment Treat with corresponding medical material disease identical.
Concrete technical scheme is as follows:
A kind of Chinese medicine dreg prepares the method for YAOSHI, comprises the following steps:
Sterilizing: Chinese medicine dreg is carried out high-temperature heat sterilization;
Fermentation: add saccharomyces cerevisiae, mix homogeneously in Chinese medicine dreg after sterilization, ferment, after obtaining fermentation Material;
Dry: dry the material after fermentation;
Pulverize: pulverize the material after drying, obtain powders A;
Dispensing: add Flos Carthami and Rhizoma Cyperi in powders A, stir, add Rhizoma Dioscoreae, purified water and preservative, stirring Uniformly, mixture B is obtained;
Pressing mold molding: according to the model designed, mixture B is carried out pressing mold, dries, obtains described Chinese medicine dreg The YAOSHI of preparation.
Wherein in some embodiments, the temperature of described sterilizing is 110 DEG C-130 DEG C, and sterilization time is 30min-60min.
Wherein in some embodiments, the temperature of described fermentation is 18-25 DEG C, and fermentation time is 25-35 days.
Wherein in some embodiments, the water content keeping fermentation materials in sweat is 55-65%.
In base in some embodiments, the described material dried after fermenting is the material after fermenting in vacuum dryer Dry to water content below 5%, dry temperature and be 70-95 DEG C.
Wherein in some embodiments, after pressing mold molding, the temperature of drying is 100-120 DEG C, and dry to YAOSHI is aqueous Amount is below 5%.
YAOSHI prepared with Chinese medicine dreg of the present invention and preparation method thereof has the following advantages and beneficial effect:
The present inventor, by long-term substantial amounts of experimentation, finds to carry out sending out to Chinese medicine dreg with saccharomyces cerevisiae After ferment, then be equipped with particular kind of Chinese crude drug, can prepare the YAOSHI treating corresponding disease, the disease of this YAOSHI treatment with What corresponding medical material was treated disease is identical, the YAOSHI such as prepared with the Chinese medicine dreg of SHIDUQING PIAN, its medicable disease Sick identical with the disease of SHIDUQING PIAN treatment.
After Chinese medicine dreg being prepared as YAOSHI by the method for the present invention, not only solve Chinese medicine dreg and directly discharge and bring Environmental problem, and make use of the remaining effective ingredient of Chinese medicine dreg to greatest extent.After Chinese medicine dreg is prepared as YAOSHI, In YAOSHI, the content of active component is far above the content of active component in medicinal residues, utilizes to greatest extent and improves Chinese medicine dreg In effective ingredient, inspire residue drug effect, be used for treating corresponding disease, effect highly significant.Achieve and Chinese medicine dreg is entered Row high added value, the target of the high-end utilization of resources.
The raw material (Flos Carthami, Rhizoma Cyperi and Rhizoma Dioscoreae powder) used by YAOSHI of the preparation present invention is nanoscale raw material, makes Chinese medicine Intracellular original some active component that can not be released of material is released due to breaking cellular wall, thus its biological activity is big Big increase, makes effective ingredient be more easy to absorb, can improve the bioavailability of medicine.
Detailed description of the invention
Below in conjunction with specific embodiment, YAOSHI prepared with Chinese medicine dreg of the present invention and preparation method thereof is entered one Step detailed description.
Embodiment 1
YAOSHI prepared by a kind of Chinese medicine dreg of the present embodiment, is prepared from the following materials:
Raw material Weight (Kg)
Chinese medicine dreg 10
Saccharomyces cerevisiae 0.005
Flos Carthami 0.001
Rhizoma Cyperi 0.001
Rhizoma Dioscoreae powder 0.05
Polylysine 0.005
Tea polyphenols 0.005
Wherein, Chinese medicine dreg is the Chinese medicine dreg of SHIDUQING PIAN, and SHIDUQING PIAN is by the raw material of Chinese medicine system of following weight portion For forming: Radix Rehmanniae 20 parts, Radix Angelicae Sinensis 20 parts, Radix Salviae Miltiorrhizae 15 parts, Periostracum Cicadae 9 parts, Radix Scutellariae 18 parts, Cortex Dictamni 20 parts, Rhizoma Smilacis Glabrae 20 parts, Radix Glycyrrhizae 9 parts.
The YAOSHI prepared with Chinese medicine dreg of the present embodiment can removing dampness removing toxic substances, dispelling wind for relieving itching, belong to blood for skin pruritus Void is wet accumulates skin card person, and its effect is identical with the effect of SHIDUQING PIAN.
The YAOSHI prepared with Chinese medicine dreg of the present embodiment, its preparation method is as follows:
Sterilizing: weigh the Chinese medicine dreg 10Kg of formula ratio, 121 DEG C of moist heat sterilization 30min;
Fermentation: spray saccharomyces cerevisiae 0.005Kg in Chinese medicine dreg after sterilization, keeps temperature 22 after mix homogeneously DEG C, heap fermentation 30 days, turning in every 4 days is once;Sweat keeps good ventilation, notes adding water when material gradually dehydration The moisture keeping fermentation materials is 55%-65%;
Dry: the material after fermentation is put in vacuum dryer, keeps temperature 75 DEG C, be dried 10 hours, moisture content control System is below 5%;
Pulverize: the material after drying carries out vacuum and smashes to 100 mesh sizes, obtains powders A;
Dispensing: adding particle diameter in powders A is the saffron powder 0.001Kg of 100nm and particle diameter is the Nutgrass Galingale Rhizome of 100nm Put into after 0.001Kg in de-airing mixer, stir;Add Rhizoma Dioscoreae powder 0.05Kg, purified water that particle diameter is 100nm 1.2Kg, poly-D-lysine 0.005Kg and tea polyphenols 0.005Kg, stir, and obtains mixture B;
Pressing mold molding: mixture B is carried out pressing mold according to the model designed and profile;Compressing YAOSHI is put Entering in dehydrator, design temperature is 110 DEG C, is dried 1.5h, and moisture control, below 5%, to obtain final product.
Embodiment 2
YAOSHI prepared by a kind of Chinese medicine dreg of the present embodiment, is prepared from the following materials:
Raw material Weight (Kg)
Chinese medicine dreg 10
Saccharomyces cerevisiae 0.005
Flos Carthami 0.001
Rhizoma Cyperi 0.001
Rhizoma Dioscoreae powder 0.05
Polylysine 0.005
Tea polyphenols 0.005
Wherein, Chinese medicine dreg is the Chinese medicine dreg of the solid gold plaque of Bulbus Lilii, and the solid gold plaque of Bulbus Lilii is that the Chinese medicine by following weight portion is former Material is prepared from: the Radix Paeoniae Alba 10 parts, Bulbus Lilii 15 parts, Bulbus Fritillariae Cirrhosae 15 parts, Radix Angelicae Sinensis 30 parts, Radix Rehmanniae 20 parts, 10 parts of Radix Glycyrrhizae, Radix Platycodonis 8 parts, wheat Winter 15 parts, Radix Rehmanniae Preparata 30 parts, Radix Scrophulariae 8 parts.
The YAOSHI prepared with Chinese medicine dreg of the present embodiment can nourishing YIN and moistening the lung, preventing phlegm from forming and stopping coughing, for YIN-deficiency of the lung and kidney, dry cough is few Expectorant, dry pharynx laryngalgia, effect of its effect gold plaque solid with Bulbus Lilii is identical.
The YAOSHI prepared with Chinese medicine dreg of the present embodiment, its preparation method is with embodiment 1.
Embodiment 3
Experiment 1: according to the YAOSHI in Chinese Pharmacopoeia version general rule 0512 high effective liquid chromatography for measuring embodiment 1 in 2015 and The active components of plants of SHIDUQING PIAN medicinal residues, measurement result is as shown in table 1.
Table 1
Main plant effective ingredient Medicinal residues YAOSHI
Baicalin 0.002% 0.042%
Ketone 0.001% 0.006%
Tanshinone 0.065% 0.363%
Catalpol 0.024% 0.625%
Ferulic acid 0.001% 0.023%
Glycyrrhizic acid 0.062% 0.852%
Rhizoma Smilacis Glabrae glycosides 0.002% 0.085%
Experiment 2: according to the YAOSHI in Chinese Pharmacopoeia version general rule 0512 high effective liquid chromatography for measuring embodiment 1 in 2015 and The active components of plants of the solid gold plaque medicinal residues of Bulbus Lilii, measurement result is as shown in table 2.
Table 2
Main plant effective ingredient Medicinal residues YAOSHI
Peoniflorin 0.002% 0.023%
Rhinanthin 0.062% 0.125%
Ophiopogonin 0.011% 0.086%
Catalpol 0.051% 0.851%
Ferulic acid 0.002% 0.026%
Glycyrrhizic acid 0.013% 0.856%
Platycodin 0.002% 0.062%
Fritimine 0.001% 0.023%
Result shows: after Chinese medicine dreg being prepared as YAOSHI by the preparation method of the present invention, and in YAOSHI, vegetable active becomes The content divided, far above the content in medicinal residues, the effective ingredient utilizing to greatest extent and improving in Chinese medicine dreg, inspires Residue drug effect.
The treatment effectiveness evaluation of embodiment 4 YAOSHI
Experiment 1: the treatment effectiveness evaluation of the YAOSHI of embodiment 1
Collecting the clinic case of 300 examples (male 168 examples, female 132 example, the range of age: 35 years old-65 years old) skin pruritus, it faces Bed symptom is skin pruritus, wet, the skin eczema of blood deficiency etc..The YAOSHI using embodiment 1 preparation is treated, treatment time For 1-5 course for the treatment of.
The using method of YAOSHI: YAOSHI wet towel is wrapped up, is placed in microwave oven, middle high fire heating 5 minutes, take out After, directly spread on affected part.Once a day, each 10-15 minute, 5 courses for the treatment of.
Therapeutic outcome is evaluated: recovery from illness, clinical symptom disappearance;Effective: clinical symptom relief;Invalid: clinical symptoms is without substantially Change.Its therapeutic effect statistics is shown in Table 3.
Interpretation of result: from table 3 result, the YAOSHI prepared with the Chinese medicine dreg of SHIDUQING PIAN of embodiment 1 can be controlled Treat the disease identical with SHIDUQING PIAN, and therapeutic effect is notable.
Experiment 2: the treatment effectiveness evaluation of the YAOSHI of embodiment 2
Collecting 300 examples (male 167 examples, female 133 example, the range of age: 35 years old-65 years old) clinic case, its clinical symptoms is lung Deficiency of the kidney yin, dry cough few expectorant, dry pharynx laryngalgia etc..The YAOSHI using embodiment 2 preparation is treated, and treatment time is the 1-5 course for the treatment of.
The using method of YAOSHI: YAOSHI wet towel is wrapped up, is placed in microwave oven, middle high fire heating 5 minutes, take out After, directly spread at back double shen shu, double fei shu.Once a day, each 10-15 minute, 5 courses for the treatment of.
Therapeutic outcome is evaluated: recovery from illness, clinical symptom disappearance;Effective: clinical symptom relief;Invalid: clinical symptoms is without substantially Change.Its therapeutic effect statistics is shown in Table 3.
Interpretation of result: from table 3 result, YAOSHI prepared by the Chinese medicine dreg with the solid gold plaque of Bulbus Lilii of embodiment 2 can Treat the disease that gold plaque solid with Bulbus Lilii is identical, and therapeutic effect is notable.
Table 3
Concrete clinical case
1, patient Zhang, man, 55 years old, waist, skin of back eczema, pruritus, red and swollen, there are more than 3 years through Western medicine antiallergic class Drug therapy is invalid.Later with the treatment of the YAOSHI of the embodiment of the present invention 1, every day in affected part external application once, each 10-15 minute, Five courses for the treatment of, after two courses for the treatment of, patient's recovery from illness, pays a return visit and does not sends out so far for 2 years.
2, patient Lee, female, 43 years old, shoulder, skin of chest pruritus were red and swollen, remaining invalid through integrative therapy one year.After The YAOSHI using the embodiment of the present invention 1 is treated, external application every day affected part once, each 10-15 minute, five courses for the treatment of, a course for the treatment of Rear patient fully recovers, and pays a return visit and does not sends out so far.
3, patient Wang, man, 62 years old, there is asthma history, the few expectorant of dry cough, throat pain, to cough night and increase the weight of, YIN-deficiency of the lung and kidney has 8 years Remaining.Invalid through integrative therapy, later with the YAOSHI treatment of this product embodiment 2, it is externally applied at back double shen shu, double fei shu, often It once, each 10-15 minute, five courses for the treatment of, after four courses for the treatment of patient recovery from illness, pay a return visit and do not send out so far for 2 years.
4, grandson patient, man, 48 years old, dry cough was had sore throat, and dry pharynx is breathed hard unable, and lumbago, YIN-deficiency of the lung and kidney has more than 3 years, through west Doctor fails to respond to any medical treatment.Later with the YAOSHI treatment of the embodiment of the present invention 2, it is externally applied at back double shen shu, double fei shu, once a day, 10-15 minute every time, 5 courses for the treatment of, patient's recovery from illness after two courses for the treatment of, pay a return visit and do not send out so far.
Each technical characteristic of embodiment described above can combine arbitrarily, for making description succinct, not to above-mentioned reality The all possible combination of each technical characteristic executed in example is all described, but, as long as the combination of these technical characteristics is not deposited In contradiction, all it is considered to be the scope that this specification is recorded.
Embodiment described above only have expressed the several embodiments of the present invention, and it describes more concrete and detailed, but also Can not therefore be construed as limiting the scope of the patent.It should be pointed out that, come for those of ordinary skill in the art Saying, without departing from the inventive concept of the premise, it is also possible to make some deformation and improvement, these broadly fall into the protection of the present invention Scope.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Claims (10)

1. the YAOSHI prepared with Chinese medicine dreg, it is characterised in that be prepared from by the raw material of following percentage by weight:
YAOSHI prepared by Chinese medicine dreg the most according to claim 1, it is characterised in that former by following percentage by weight Material is prepared from:
YAOSHI prepared by Chinese medicine dreg the most according to claim 1 and 2, it is characterised in that described Chinese medicine dreg is wet The Chinese medicine dreg of the clear sheet of poison or the Chinese medicine dreg of the solid gold plaque of Bulbus Lilii.
YAOSHI prepared by Chinese medicine dreg the most according to claim 1 and 2, it is characterised in that described Flos Carthami is that particle diameter is The saffron powder of 100nm-120nm, described Rhizoma Cyperi be particle diameter be the Nutgrass Galingale Rhizome of 100nm-120nm, described Rhizoma Dioscoreae is that particle diameter is The Rhizoma Dioscoreae powder of 100nm-120nm.
5. a preparation method for the YAOSHI prepared with Chinese medicine dreg described in any one of claim 1-4, comprises the following steps:
Sterilizing: Chinese medicine dreg is carried out high-temperature heat sterilization;
Fermentation: add saccharomyces cerevisiae, mix homogeneously in Chinese medicine dreg after sterilization, ferment, obtain the material after fermentation;
Dry: dry the material after fermentation;
Pulverize: pulverize the material after drying, obtain powders A;
Dispensing: add Flos Carthami and Rhizoma Cyperi in powders A, stir, add Rhizoma Dioscoreae, purified water and preservative, stir, Obtain mixture B;
Pressing mold molding: according to the model designed, mixture B is carried out pressing mold, dries, obtains described Chinese medicine dreg and prepare YAOSHI.
Preparation method the most according to claim 5, it is characterised in that the temperature of described sterilizing is 110 DEG C-130 DEG C, sterilizing Time be 30min-60min.
Preparation method the most according to claim 5, it is characterised in that the temperature of described fermentation is 18-25 DEG C, fermentation time Between be 25-35 days.
Preparation method the most according to claim 5, it is characterised in that the water content keeping fermentation materials in sweat is 55-65%.
Preparation method the most according to claim 5, it is characterised in that the material after described drying fermentation is at vacuum drying Drying materials after fermenting in machine is to water content below 5%, and the temperature of drying is 70-95 DEG C.
Preparation method the most according to claim 5, it is characterised in that after pressing mold molding, the temperature of drying is 100-120 DEG C, the water content of drying to YAOSHI is below 5%.
CN201610848719.XA 2016-09-23 2016-09-23 Medicine stone prepared from traditional Chinese medicine dregs and preparation method thereof Pending CN106310042A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109453279A (en) * 2018-12-26 2019-03-12 深圳德道生物科技有限公司 A kind of Chinese medicine composition and external application of Chinese medicine ointment of conditioning myopia
CN111134321A (en) * 2020-01-16 2020-05-12 张盛南 A method for processing radix Ginseng

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* Cited by examiner, † Cited by third party
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陆欣媛等: "《中药发酵研究概况》", 《黑龙江医药》 *
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109453279A (en) * 2018-12-26 2019-03-12 深圳德道生物科技有限公司 A kind of Chinese medicine composition and external application of Chinese medicine ointment of conditioning myopia
CN111134321A (en) * 2020-01-16 2020-05-12 张盛南 A method for processing radix Ginseng

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Application publication date: 20170111