CN106309151A - Protein vitamin pink mask liquid and production method - Google Patents

Protein vitamin pink mask liquid and production method Download PDF

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Publication number
CN106309151A
CN106309151A CN201610688008.0A CN201610688008A CN106309151A CN 106309151 A CN106309151 A CN 106309151A CN 201610688008 A CN201610688008 A CN 201610688008A CN 106309151 A CN106309151 A CN 106309151A
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vitamin
content
albumen
pink
mask liquid
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杨霞
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Shanxi Jinbo Bio Pharmaceutical Co ltd
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Shanxi Jin Bo Biomedics Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212Face masks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/24Phosphorous; Compounds thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives

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Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to protein vitamin pink mask liquid and a production method thereof. The mask liquid comprises active substances and a nutritional component, wherein the active substances are recombinant human collagen and oligopeptide-1 protein; the nutritional component is vitamin B12; the content of the recombinant human collagen is 0.0002-0.001%; the content of the oligopeptide-1 protein is 0.0002-0.001%; the content of the vitamin B12 is 0.0005-0.005%; the active substances and the nutritional component are dissolved in a balanced salt solution. The protein vitamin pink mask liquid contains a variety of nutritional ions, provides a good growing environment for skin cells, can make rough skin white, compact, tender and smooth after long-term use, and has efficacy of rapidly repairing damaged skin, moisturizing the skin, enhancing skin elasticity, compacting the skin, whitening the skin and removing freckles.

Description

The pink facial mask liquid of albumen vitamin and production method
Technical field
The invention belongs to cosmetic technical field, specially the pink facial mask liquid of albumen vitamin and production method thereof.
Background technology
Facial film is the most common a kind of skin care item.Mainly by acting the of short duration time covered at face, outside being temporarily isolating Boundary's environment, makes skin temperature raise, and skin pore is expanded, and accelerates sweat gland secretion and blood circulation, makes in skin oxygen content Rise, accelerate to get rid of oil substances in the metabolic product of skin epidermis and skin.Meanwhile, the moisture in facial film, nutrition become Divide, active component penetrates into epidermis cell, makes skin become soft, and it is flexible that skin is rich in gloss.
Facial film mainly has mud cream type, tear-pull, gel-type, four kinds of l Water Paper type at present.
Summary of the invention
It is an object of the invention to provide albumen vitamin pink mask product formula and production technology thereof.This product with Recombination human source collagen protein and oligopeptide-1 albumen are main active substances, with vitamin B12 as nutritional labeling.
The present invention adopts the following technical scheme that realization:
A kind of pink facial mask liquid of albumen vitamin, including active substance and nutritional labeling, described active substance is recombination human source glue Former albumen and oligopeptide-1 albumen, described nutritional labeling is vitamin B12.
The recombination human source collagen protein of active component, for type III human collagen, sequence is the sequence of long-term screening and optimizing Row, use escherichia expression system, and the sequence in gene has carried out codon optimized expression for escherichia expression system Form, its preparation method as 201210482543.2(recombination human source collagen protein and production method thereof) described in.This is heavy Group people's derived collagen albumen has extraordinary hydrophilic and stability, its aminoacid composition and natural collagen protein aminoacid sequence Appropriate section 100% is identical, is applied to human body and will not produce immunologic rejection and anaphylaxis, can be widely applied to biological medicine And cosmetic industry, the function of native protein can be exercised in human body.
Oligopeptide-1 of active component, i.e. EGF(recombinant human epidermal growth factor).EGF can promote the proliferation and differentiation of cell, Thus replace senile cell and the process of dead cell with regenerative cell.What Traditional makeup rose is outside modification, it is impossible to Fundamentally solve skin problem, and EGF applies the physiological structure being based on human body skin in cosmetics, at molecular water On Ping, cell repaired and adjust, having and quickly repair damaged skin, improving the reparation of skin, nursing;Skin care, increases Strong skin elasticity, calms down eye wrinkle-removing, firm skin;Whitening and speckle dispelling, sun-proof and after-sun;And there is anti-acne, go scar Trace, shortening wound healing time and the effect of minimizing cicatrization, be described as " the beautiful factor " by beauty treatment circle.This oligopeptide-1 preparation side Method is shown in the method that 200810211603.0(prepares dissolvable high activity recombinant human epidermal growth factor) record, repeat no more.
Vitamin B12 is again cobalamine (cobalamin), is the vitamin uniquely containing metallic element, ties for light red needle-like Crystalline substance, soluble in water and ethanol, the most stable under pH value 4.5~5.0 mild acid conditions, strong acid (pH < 2) or alkaline solution decompose, Heat can have to a certain degree to be destroyed, but the high-temperature sterilization of short time loss is little, meets high light or ultraviolet is easily destroyed.In skin protection Cosmetic can be obviously improved skin is tired out, obscure, dry skin;Substantially desalinate the microgroove produced because of the age and wrinkle;Maintenance day Shine, the autumn and winter are dried etc. that the skin caused is red and swollen, decortication, pain;Repair pox cicatrix mark, the cicatrix of mosquito bite, empyrosis and The cicatrix that plastic operation stays.
Facial mask liquid of the present invention is with recombination human source collagen protein and oligopeptide-1 albumen as main active substances, with vitamin B12 For nutritional labeling.
Preferably, with facial mask liquid weight for counting, the content of described recombination human source collagen protein is 0.0002 ~ 0.001%;Institute The content stating oligopeptide-1 albumen is 0.0002 ~ 0.001%;The content of described vitamin B12 is 0.0005 ~ 0.005%.
Preferably, described active substance and nutritional labeling are dissolved in balanced salt solution.Balanced salt solution, i.e. main by inorganic Salt, glucose form, and are the internal salinity of biological maintenance and the liquid of body fluid balance, can maintain cell normal osmosis and replacement, protect Hold pH stable, provide comfortable production metabolism environment for regenerative cell, and necessary nutrient ions is provided.
Described balanced salt solution includes potassium chloride, magnesium sulfate, sodium chloride, sodium dihydrogen phosphate, L-glutaminate and glucose sugar, Wherein, in terms of facial mask liquid weight, the content of potassium chloride is 0.02 ~ 0.05%, and the content of magnesium sulfate is 0.01 ~ 0.05%, sodium chloride Content be 0.5 ~ 0.8%, the content of sodium dihydrogen phosphate is 0.01 ~ 0.03%, and the content of L-glutaminate is 0.05 ~ 0.08%, Portugal The content of grape sugar is 0.2 ~ 0.5%.
Preferably, described balanced salt solution adds glycerol, γ-aminobutyric acid, Sodium Pyruvate and hyaluronate sodium.
Glycerol is achromaticity and clarification thick liquid, and odorless has warm sweet taste.Be widely used in medicine, food, cosmetics, toothpaste, Nicotiana tabacum L. etc..Can be as good solvent, wetting agent etc. in cosmetics.
γ-aminobutyric acid (γ-aminobutyric acid (GABA)) is a kind of active skull cap components, widely distributed In animal and plant body, white plates or acicular crystal;Micro-smelly, there is hygroscopy;It is highly soluble in water, is slightly soluble in hot ethanol, insoluble In cold ethanol, ether and benzene.Being inhibitory neurotransmitter critically important in central nervous system, it participates in multiple metabolic activity, There is the highest physiologically active.Up-to-date research shows, GABA has and prevents skin aging, eliminates body odor, improves lipid metabolism, Prevent the functions such as arteriosclerosis high-efficient fat reducing.
Sodium Pyruvate is modal pyruvate, calls pyruvic sodium, 2-carbonyl propionic acid sodium, white crystalline powder; Soluble in water, atomic it is dissolved in alcohol.Being a class endogenous small-molecule substance, Sodium Pyruvate and acetone acid are all naturally present in human body In, and participate in whole body and respectively organize the metabolism with organ, it is required material in cellular metabolism.
Hyaluronate sodium (Sodium Hyaluronate): for the material extracted from cockscomb, it is possible to pass through Lactococcus Fermentation prepares, and for white or off-white color granule or powder, odorless, has the strongest hygroscopicity, is dissolved in water, insoluble in alcohol, ketone, second The organic solvents such as ether.Its aqueous solution is electronegative, has the highest viscoelasticity, rheological characteristic and osmotic pressure during high concentration.At cosmetics Field uses more, have moisture-keeping function.In the products such as the cream of cosmetics, frost, honey, milk, facial film, shampoo, have solely Special keeps skin, the moisture of hair, makes skin moisturizing smooth, and fine and smooth tender, high resilience, hair is rich in gloss;Have simultaneously Have and prevent chapped skin, wrinkle resistant crease-resistant, aesthetic health care and the effect of recovery skin physiology function.
Preferably, in terms of facial mask liquid weight, the content of described glycerol is 5 ~ 8%, and the content of described γ-aminobutyric acid is 0.0002 ~ 0.001%, the content of described Sodium Pyruvate is 0.01 ~ 0.015%, and the content of described hyaluronate sodium is 0.2 ~ 0.5%.
It addition, facial mask liquid can also be added preservative PE 9010 in right amount.PE 9010 is phenoxyethanol and ethylhexyl The liquid preservative used for cosmetic that glycerol is compounding, Sensiva SC50 have impact on the surface tension on microbial cell film, thus Improve the antiseptic power of phenoxyethanol.Antibacterial, yeast and mycete are had the inhibitory action of wide spectrum equilibrium, is a kind of typical Antibacterial aseptic production, also has certain sterilizing ability simultaneously.PE 9010 is highly stable, not facile hydrolysis.Temperature and pH value are had There is good toleration.Its favorable solubility, even if the most also can be well dispersed in each system.
Containing multiple nutrients ion in the pink facial mask liquid of albumen vitamin of the present invention, provide good life for skin cell Long environment, life-time service can make that rough skin is pale to compact, tender smooth, and have and quickly repair damaged skin, moistens skin Skin, strengthens skin elasticity, firm skin, the effectiveness of whitening and speckle dispelling.
A kind of facial film, including face paper, described face paper infiltrates above-mentioned facial mask liquid.Described face paper is silkworm silk face Film.
L Water Paper type is exactly the face paper infiltrating facial mask liquid of mmic package, and the face paper of this product is a kind of by silkworm silk system Become, therefore belong to l Water Paper profile film.Silk mask, is mainly made up of silk fiber and activity fibroin.Due to fibroin In containing 18 kinds of aminoacid of nutritive value great to human body, and be the splendid porous material of good permeability, water absorption, And non-stimulated to skin, there is " artificial skin " laudatory title.Silk mask has the strongest adsorptivity, can carry attached more facial film elite Liquid, applies face more comfortable, more firmly, does not haves and fall down and facial mask liquid drip phenomenon.Silk mask uses the softst exquisiteness Silkworm silk, can be close to skin texture, therefore the highest at the docile degree of deposited face, and matter is thin, transparent, ventilative, and the wing of nose corners of the mouth can take Note, lock water moisturizing is persistently deeply.And silk mask can accelerate the reparation of skin self, can be closed by the fine and smooth note of silk fiber Impaired skin is allowed to rapidly be reparation.Heavier can promote the secretion of collagen protein, potent brighten, uvioresistant, antiinflammatory and pock Ability.
The pink facial film of albumen vitamin of the present invention is reasonable in design, after only needing face cleaning, takes out facial film and spreads on face, make silkworm silk Face skin is everywhere close to by facial film, waits for percutaneous absorption facial mask liquid quietly, after 15-20min, removes facial film, No clean, is massaged into gently Absorb.
Detailed description of the invention
Below the specific embodiment of the present invention is described in detail.
Embodiment 1
A kind of pink facial mask liquid of albumen vitamin, including component A, B component and component C, surplus is water;With facial mask liquid gross weight it is Meter is the most identical.
Described component A is made up of following components by weight percent:
Potassium chloride 0.04%,
Magnesium sulfate 0.01%,
Sodium chloride 0.64%,
Sodium dihydrogen phosphate 0.0125%,
L-glutaminate 0.0584%,
Glucose 0.45%,
Sodium Pyruvate 0.011%,
γ-aminobutyric acid 0.0005%,
Hyaluronate sodium 0.4%,
Glycerol 6%;
Described B component is made up of following components by weight percent:
Oligopeptide-1 albumen 0.0005%,
Vitamin B12 0.001%,
Collagen protein 0.0005%;
Described component C is made up of following components by weight percent:
PE9010(phenoxyethanol/Sensiva SC50) 0.35%.
The production method of the above-mentioned pink facial mask liquid of albumen vitamin, comprises the steps:
(1), component A is dissolved in pure water, stirs so that it is fully dissolve;
(2), 115 DEG C of sterilizings 30 minutes;
(3), when being down to 40 DEG C, the cobalamin in component C, B component and the activated protein of the membrane filtration by 0.22 μm are added, then Continue to stir;
(4), finally regulation pH value, between 5.5 to 6.0, gets product.Fill, sealing, packaging.
Embodiment 2
A kind of pink facial mask liquid of albumen vitamin, including component A, B component and component C, surplus is water;
Described component A is made up of following components by weight percent:
Potassium chloride 0.02%,
Magnesium sulfate 0.03%,
Sodium chloride 0.6%,
Sodium dihydrogen phosphate 0.01%,
L-glutaminate 0.05%,
Glucose 0.4%,
Sodium Pyruvate 0.012%,
γ-aminobutyric acid 0.0008%,
Hyaluronate sodium 0.2%,
Glycerol 8%;
Described B component is made up of following components by weight percent:
Oligopeptide-1 albumen 0.0008%,
Vitamin B12 0.0005%,
Collagen protein 0.0002%;
Described component C is made up of following components by weight percent:
PE9010(phenoxyethanol/Sensiva SC50) 0.35%.
Preparation method is with embodiment 1.
Embodiment 3
A kind of pink facial mask liquid of albumen vitamin, including component A, B component and component C, surplus is water;
Described component A is made up of following components by weight percent:
Potassium chloride 0.03%,
Magnesium sulfate 0.05%,
Sodium chloride 0.5%,
Sodium dihydrogen phosphate 0.02%,
L-glutaminate 0.07%,
Glucose 0.3%,
Sodium Pyruvate 0.01%,
γ-aminobutyric acid 0.0002%,
Hyaluronate sodium 0.5%,
Glycerol 5%;
Described B component is made up of following components by weight percent:
Oligopeptide-1 albumen 0.0006%,
Vitamin B12 0.005%,
Collagen protein 0.0007%;
Described component C is made up of following components by weight percent:
PE9010(phenoxyethanol/Sensiva SC50) 0.35%.
Preparation method is with embodiment 1.
Embodiment 4
A kind of pink facial mask liquid of albumen vitamin, including component A, B component and component C, surplus is water;
Described component A is made up of following components by weight percent:
Potassium chloride 0.05%,
Magnesium sulfate 0.04%,
Sodium chloride 0.8%,
Sodium dihydrogen phosphate 0.03%,
L-glutaminate 0.06%,
Glucose 0.2%,
Sodium Pyruvate 0.015%,
γ-aminobutyric acid 0.001%,
Hyaluronate sodium 0.3%,
Glycerol 7%;
Described B component is made up of following components by weight percent:
Oligopeptide-1 albumen 0.0002%,
Vitamin B12 0.003%,
Collagen protein 0.001%;
Described component C is made up of following components by weight percent:
PE9010(phenoxyethanol/Sensiva SC50) 0.35%.
Preparation method is with embodiment 1.
Embodiment 5
A kind of pink facial mask liquid of albumen vitamin, including component A, B component and component C, surplus is water;
Described component A is made up of following components by weight percent:
Potassium chloride 0.04%,
Magnesium sulfate 0.02%,
Sodium chloride 0.7%,
Sodium dihydrogen phosphate 0.015%,
L-glutaminate 0.08%,
Glucose 0.5%,
Sodium Pyruvate 0.014%,
γ-aminobutyric acid 0.0006%,
Hyaluronate sodium 0.4%,
Glycerol 6.5%;
Described B component is made up of following components by weight percent:
Oligopeptide-1 albumen 0.001%,
Vitamin B12 0.002%,
Collagen protein 0.0007%;
Described component C is made up of following components by weight percent:
PE9010(phenoxyethanol/Sensiva SC50) 0.35%.
Preparation method is with embodiment 1.
It should be noted last that, above example is only in order to illustrate technical scheme and unrestricted, although ginseng It is described in detail according to the embodiment of the present invention, it will be understood by those within the art that, to technical scheme Modifying or equivalent, without departure from the spirit and scope of technical scheme, it all should contain the present invention's In claims.

Claims (10)

1. the pink facial mask liquid of albumen vitamin, it is characterised in that: include active substance and nutritional labeling, described active substance For recombined human derived collagen albumen and oligopeptide-1 albumen, described nutritional labeling is vitamin B12.
The pink facial mask liquid of albumen vitamin the most according to claim 1, it is characterised in that: described recombination human source collagen protein Content be 0.0002 ~ 0.001%;The content of described oligopeptide-1 albumen is 0.0002 ~ 0.001%;The content of described vitamin B12 It is 0.0005 ~ 0.005%.
The pink facial mask liquid of albumen vitamin the most according to claim 1 and 2, it is characterised in that: described active substance and battalion Form and point be dissolved in balanced salt solution.
The pink facial mask liquid of albumen vitamin the most according to claim 3, it is characterised in that: described balanced salt solution adds Glycerol, γ-aminobutyric acid, Sodium Pyruvate and hyaluronate sodium.
The pink facial mask liquid of albumen vitamin the most according to claim 4, it is characterised in that: the content of described glycerol is 5 ~ 8%, the content of described γ-aminobutyric acid is 0.0002 ~ 0.001%, and the content of described Sodium Pyruvate is 0.01 ~ 0.015%, described The content of hyaluronate sodium is 0.2 ~ 0.5%.
The pink facial mask liquid of albumen vitamin the most according to claim 5, it is characterised in that: described balanced salt solution includes chlorine Change potassium, magnesium sulfate, sodium chloride, sodium dihydrogen phosphate, L-glutaminate and glucose sugar, wherein, the content of potassium chloride is 0.02 ~ 0.05%, the content of magnesium sulfate is 0.01 ~ 0.05%, and the content of sodium chloride is 0.5 ~ 0.8%, the content of sodium dihydrogen phosphate is 0.01 ~ 0.03%, the content of L-glutaminate is 0.05 ~ 0.08%, and the content of glucose is 0.2 ~ 0.5%.
The pink facial mask liquid of albumen vitamin the most according to claim 6, it is characterised in that: include component A, B component and C group Point, surplus is water;
Described component A is made up of following components by weight percent:
Potassium chloride 0.04%,
Magnesium sulfate 0.01%,
Sodium chloride 0.64%,
Sodium dihydrogen phosphate 0.0125%,
L-glutaminate 0.0584%,
Glucose 0.45%,
Sodium Pyruvate 0.011%,
γ-aminobutyric acid 0.0005%,
Hyaluronate sodium 0.4%,
Glycerol 6%;
Described B component is made up of following components by weight percent:
Oligopeptide-1 albumen 0.0005%,
Vitamin B12 0.001%,
Collagen protein 0.0005%;
Described component C is made up of following components by weight percent:
PE9010 0.35%。
8. the production method of the pink facial mask liquid of albumen vitamin described in a claim 7, it is characterised in that: include walking as follows Rapid:
(1), component A is dissolved in pure water, stirs so that it is fully dissolve;
(2), 115 DEG C of sterilizings 30 minutes;
(3), when being down to 40 DEG C, the cobalamin in component C, B component and the activated protein of the membrane filtration by 0.22 μm are added, then Continue to stir;
(4), finally regulation pH value, to 5.5 ~ 6.0, gets product.
9. a facial film, including face paper, it is characterised in that: infiltration facial mask liquid described in claim 1-7 on described face paper.
Facial film the most according to claim 9, it is characterised in that: described face paper is silk mask.
CN201610688008.0A 2016-08-19 2016-08-19 Protein vitamin pink mask liquid and production method Pending CN106309151A (en)

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CN113456522A (en) * 2021-05-19 2021-10-01 太原理工大学 Hand cream with recombinant human collagen as nutrient component and preparation method thereof
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Cited By (6)

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Publication number Priority date Publication date Assignee Title
CN109846779A (en) * 2019-03-06 2019-06-07 上海乐宝日化股份有限公司 A kind of maintenance makeup remover and preparation method thereof containing vitamin B12
CN111053719A (en) * 2020-01-06 2020-04-24 广州品域美妆创新科技有限公司 Soothing and whitening composition containing vitamin B12 and application thereof
CN113456522A (en) * 2021-05-19 2021-10-01 太原理工大学 Hand cream with recombinant human collagen as nutrient component and preparation method thereof
CN114886837A (en) * 2022-04-20 2022-08-12 陕西时光未来生物科技有限公司 Eye essence and preparation method thereof
CN114886837B (en) * 2022-04-20 2024-06-11 山东时光未来生物科技有限公司 Eye essence and preparation method thereof
CN116350536A (en) * 2023-03-20 2023-06-30 上海肌效派生物科技有限公司 Recombinant humanized collagen composition and application thereof

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