CN1062902C - 在宿主细胞中生产脂酰还原酶的方法 - Google Patents

在宿主细胞中生产脂酰还原酶的方法 Download PDF

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Publication number
CN1062902C
CN1062902C CN92102206A CN92102206A CN1062902C CN 1062902 C CN1062902 C CN 1062902C CN 92102206 A CN92102206 A CN 92102206A CN 92102206 A CN92102206 A CN 92102206A CN 1062902 C CN1062902 C CN 1062902C
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China
Prior art keywords
reductase
acyl
reductase enzyme
sequence
enzyme
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Expired - Fee Related
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CN92102206A
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English (en)
Chinese (zh)
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CN1064312A (zh
Inventor
J·G·梅茨
M·R·波拉德
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Monsanto Co
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Calgene LLC
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Priority claimed from US07/767,251 external-priority patent/US5403918A/en
Application filed by Calgene LLC filed Critical Calgene LLC
Publication of CN1064312A publication Critical patent/CN1064312A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01042—Hexadecanal dehydrogenase (acylating) (1.2.1.42), i.e. fatty acyl-CoA reductase

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN92102206A 1991-02-22 1992-02-22 在宿主细胞中生产脂酰还原酶的方法 Expired - Fee Related CN1062902C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US65997591A 1991-02-22 1991-02-22
US659,975 1991-02-22
US767,251 1991-09-27
US07/767,251 US5403918A (en) 1991-02-22 1991-09-27 Fatty acyl reductase
US79625691A 1991-11-20 1991-11-20
US796,256 1991-11-20

Publications (2)

Publication Number Publication Date
CN1064312A CN1064312A (zh) 1992-09-09
CN1062902C true CN1062902C (zh) 2001-03-07

Family

ID=27418024

Family Applications (1)

Application Number Title Priority Date Filing Date
CN92102206A Expired - Fee Related CN1062902C (zh) 1991-02-22 1992-02-22 在宿主细胞中生产脂酰还原酶的方法

Country Status (7)

Country Link
US (1) US5370996A (enExample)
EP (1) EP0529048A4 (enExample)
KR (1) KR100236483B1 (enExample)
CN (1) CN1062902C (enExample)
CA (1) CA2079113A1 (enExample)
TW (1) TW272232B (enExample)
WO (1) WO1992014816A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723747A (en) * 1991-02-22 1998-03-03 Calgene, Inc. Wax esters in transformed plants
US5910630A (en) * 1994-04-06 1999-06-08 Davies; Huw Maelor Plant lysophosphatidic acid acyltransferases
US6492509B1 (en) 1994-06-23 2002-12-10 Calgene Llc Fatty acyl-CoA: fatty alcohol acyltransferases
US7332311B2 (en) 1994-06-23 2008-02-19 Calgene Llc Fatty acyl-CoA: fatty alcohol acyltransferases
GB9414622D0 (en) * 1994-07-20 1994-09-07 Zeneca Ltd Beta-ketoacylacp reductase genes from brassica napus
US5633151A (en) * 1994-11-04 1997-05-27 The United States Of America As Represented By The Secretary Of Agriculture Enzymatic process for the isolation of erucic acid from vegetable oils
TW321649B (enExample) * 1994-11-12 1997-12-01 Zeneca Ltd
US5576197A (en) * 1995-04-07 1996-11-19 Molecular Bio-Products Polymerase chain reaction container and methods of using the same
US6307128B1 (en) * 1997-06-03 2001-10-23 Miami University Fatty acid elongases
EP0986647B1 (en) 1997-06-05 2006-04-19 Calgene LLC FATTY ACYL-CoA: FATTY ALCOHOL ACYLTRANSFERASES
CN1298001A (zh) * 1999-11-24 2001-06-06 上海博容基因开发有限公司 一种新的多肽——人酰基辅酶a还原酶55和编码这种多肽的多核苷酸
AU2002258979A1 (en) * 2001-04-23 2003-01-02 Desert Whale Jojoba Company, Inc. Method of preparing and formulations including hydrolyzed jojoba protein
WO2008100251A1 (en) * 2007-02-13 2008-08-21 Ls9, Inc. Modified microorganism uses therefor
KR20100015763A (ko) * 2007-03-28 2010-02-12 엘에스9, 인코포레이티드 지방산 유도체의 생산 증가
AU2009246083A1 (en) * 2008-05-16 2009-11-19 Ls9, Inc. Methods and compositions for producing hydrocarbons
CN102471781B (zh) 2009-06-30 2015-03-18 科德克希思公司 以脂肪醇形成酰基CoA还原酶(FAR)产生脂肪醇
US7794969B1 (en) 2009-07-09 2010-09-14 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
US7955820B1 (en) 2009-07-09 2011-06-07 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
WO2011019858A1 (en) 2009-08-11 2011-02-17 Synthetic Genomics, Inc. Microbial production of fatty alcohols
US8574878B2 (en) 2010-06-28 2013-11-05 Behnaz Behrouzian Fatty alcohol forming acyl reductases (FARs) and methods of use thereof
WO2012129537A1 (en) 2011-03-23 2012-09-27 Joule Unlimited Technologies, Inc. Photoalkanogens with increased productivity
MX355504B (es) 2011-09-27 2018-04-19 Exxonmobil Res & Eng Co Éster de cera de proteína portadora de acil-acil sintasas.
EP3921328A1 (en) * 2019-02-08 2021-12-15 Lubrizol Advanced Materials, Inc. Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
NZ221259A (en) * 1986-07-31 1990-05-28 Calgene Inc Seed specific transcriptional regulation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
THE BITCHISTRY OF PLANTD VOL.4 1980.1.1 p.e.kolattudy "cutin subein and waxcs' *
THE BITCHISTRY OF PLANTD VOL.4 1980.1.1 p.e.kolattudy "cutin subein and waxcs';THE JOUMAL OF THE AMERICAN OIL CHENIXTIY SOTIETY VOL.52 1975.1.1 d.m.yemanos compotion of jojoba secd dumig development' *
THE JOUMAL OF THE AMERICAN OIL CHENIXTIY SOTIETY VOL.52 1975.1.1 d.m.yemanos compotion of jojoba secd dumig development' *

Also Published As

Publication number Publication date
CN1064312A (zh) 1992-09-09
KR100236483B1 (ko) 2000-01-15
TW272232B (enExample) 1996-03-11
US5370996A (en) 1994-12-06
EP0529048A1 (en) 1993-03-03
CA2079113A1 (en) 1992-08-23
WO1992014816A1 (en) 1992-09-03
EP0529048A4 (en) 1994-08-17

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SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C15 Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993)
OR01 Other related matters
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee