CN106269143A - A kind of Chinese crude drug preprocess method - Google Patents
A kind of Chinese crude drug preprocess method Download PDFInfo
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- CN106269143A CN106269143A CN201610781149.7A CN201610781149A CN106269143A CN 106269143 A CN106269143 A CN 106269143A CN 201610781149 A CN201610781149 A CN 201610781149A CN 106269143 A CN106269143 A CN 106269143A
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- crude drug
- chinese crude
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C19/00—Other disintegrating devices or methods
- B02C19/18—Use of auxiliary physical effects, e.g. ultrasonics, irradiation, for disintegrating
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- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of Chinese crude drug preprocess method, after comprising the steps: that Chinese crude drug is cleared up remove impurity by (1), use and soak or spray pattern raising water content, seal after dewatering and carry out sam；(2) adjust the Chinese crude drug after moisture and load in steam explosion device, seal, use electrical heating or direct open firing, boost to moment release after preset pressure, and pressurize certain time, complete steam explosion collection material.The steam explosion preconditioning technique that the present invention uses is an of short duration high temperature preprocessing process of the biological characteristics design according to Chinese crude drug; be conducive to the reservation of active ingredient; the original physiologically active of Chinese crude drug can be kept to greatest extent; its contained various natural function compositions are made to obtain the protection of maximum in preprocessing process; Chinese crude drug fiber and cell wall can be destroyed simultaneously; be conducive to goal object dissolution, follow-up extraction is had positive role.
Description
Technical field
The present invention relates to a kind of Preparation process method of Chinese crude drug, specifically, relate to a kind of Chinese crude drug preprocess method.
Background technology
Chinese crude drug processing and utilization field is most important is exactly effectively extracting and utilizing, merit functional components all kinds of in medical material
Effective component content is to weigh medicine, health food or the important evidence of Related product quality often.Chinese crude drug extracts and answers at present
The most delayed with technology especially preconditioning technique, it is only limitted to the technology such as immersion, coarse pulverization, functional component extraction ratio is promoted
Contribute limited.Major part medical material all contains substantial amounts of fibre structure and the composition such as pectin, protein, and this makes to concoct at Chinese crude drug
During, effective ingredient is difficult to dissolution, and general crushing technology degree of grinding is less, also cannot destroy cell wall.And it is the most normal
The breaking method Chang Yinwei crushing process of rule produces heat and makes the active ingredient volatilization in medical material or loss, cause Chinese crude drug product
Matter declines, thus is unfavorable for the extraction processing technique of its follow-up active ingredient.Above-mentioned factor slow down me to a certain extent
The process of state's Chinese crude drug modernization.Present need exist for a kind of preferable effective Chinese crude drug preconditioning technique and solve this difficult problem.
Steam explosion (also known as air blasting) its principle of technology mainly has the material of certain moisture to dash forward by high temperature, high pressure in moment
So dropping to room temperature, normal pressure, the moisture within raw material vaporizes suddenly, and gas expands suddenly, occurs spray quick-fried, produces demolition effect.Vapour
Quick-fried pretreatment can make material tissue be spongy, and volume increases, and some structure organizations such as fibre bundle etc. is destroyed, and inclusions is sudden and violent
Dew, the beneficially dissolution of goal object.Steam explosion technology is currently mainly applied at pulping and papermaking industry, waste paper recovery, lignocellulose raw material
The aspects such as the pretreatment of bioconversion, and do not relate in Chinese crude drug extracts.
Summary of the invention
It is an object of the invention to cause, for current Chinese crude drug preconditioning technique deficiency, the problem that functional component extraction ratio is low,
Disclose the Chinese crude drug preprocess method of a kind of steam explosion, in the case of ensureing that Chinese crude drug active component is constant, utilize steam explosion to bring
Expansion, spray quick-fried phenomenon and make the fibre structure of Chinese crude drug, cell wall etc. destroyed, strengthen the contact surface area of material, in improving
Tolerant dissolution rate, in order to subsequent extracted, improves functional component extraction ratio.
To achieve these goals, the present invention adopts the following technical scheme that
A kind of Chinese crude drug preprocess method, comprises the steps:
(1), after Chinese crude drug being cleared up remove impurity, use and soak or spray pattern improves water content, seal after dewatering and carry out sam and make it
Internal moisture equalizes；
(2) adjust the Chinese crude drug after moisture and load in steam explosion device, seal, use electrical heating or direct open firing, boost to
Moment release after preset pressure, and pressurize certain time, completes steam explosion collection material.
In above-mentioned Chinese crude drug preprocess method, the moisture after described adjustment moisture is 50-250%.
In above-mentioned Chinese crude drug preprocess method, described electrical heating or directly open firing maintain the temperature at 150-250
℃。
In above-mentioned Chinese crude drug preprocess method, described pressure is 0.4-1.2MPa.
In above-mentioned Chinese crude drug preprocess method, described Chinese crude drug is Poria, Lentinus Edodes, Herba Dendrobii, the Radix Astragali or Tremella.
Compared with prior art, there is advantages that the steam explosion preconditioning technique that the present invention uses is root
The of short duration high temperature preprocessing process designed according to the biological characteristics of Chinese crude drug, beneficially the reservation of active ingredient, permissible
Keep the original physiologically active of Chinese crude drug to greatest extent so that it is contained various natural function compositions are in preprocessing process
Obtaining maximum protection, can destroy Chinese crude drug fiber and cell wall simultaneously, beneficially goal object dissolution, to follow-up extraction tool
There is positive role.Additionally, steam explosion technology is lower relative to conventional size reduction technology energy consumption, technical merit is ripe, and technique is simple, operation
Convenient, seriality is good, treating capacity is big, easily realizes industrialization, to the production technology level of Chinese crude drug product and the modernization of Chinese medicine
Process has huge impetus.
Accompanying drawing explanation
Fig. 1 is that steam explosion affects figure to pachyman extraction ratio；
Fig. 2 is that steam explosion affects figure to lentinan extraction ratio.
Detailed description of the invention
In order to be more clearly understood that the technology contents of the present invention, describe in detail especially exemplified by following example, but the present invention
Embodiment be not limited to this.
Embodiment 1: the steam explosion pretreatment impact on pachyman extraction ratio
(1) taking 2 groups of each 500g of Poria sample, add distilled water, being dipped to its water content is 100%, in 4L test steam-explosion jar
With 170 DEG C, 1 MPa pressurize 30s and 60s respectively, steam explosion process terminates rear collection material.Decoction and alcohol sedimentation technique is used to extract Poria many
Sugar also measures polysaccharide extract rate.
(2) take same batch Poria sample 500g, directly use decoction and alcohol sedimentation technique extract pachyman and measure Polyose extraction
Rate.
(3) polyoses content in 3 kinds of extracting solution is compared, result such as Fig. 1:
Steam explosion 30s and two groups of sample polysaccharide extract rates of steam explosion 60s are carried by without the 0.964% of steam explosion matched group respectively as seen from Figure 1
Rise to 6.332% and 9.795%, exceed 5.56 times and 9.16 times.Test absolutely proves that steam explosion pretreatment can significantly improve Poria
Polysaccharide extract rate.
Embodiment 2: the steam explosion pretreatment impact on lentinan extraction ratio
(1) taking 2 groups of each 500g of Lentinus Edodes sample, add distilled water, being dipped to its water content is 150%, in 5L test steam-explosion jar
With 170 DEG C, 1 MPa pressurize 30s and 60s respectively, steam explosion process terminates rear collection material.Decoction and alcohol sedimentation technique is used to extract polysaccharide also
Measure polysaccharide extract rate.
(2) take same batch Lentinus Edodes sample 500g, directly use decoction and alcohol sedimentation technique extract lentinan and measure Polyose extraction
Rate.
(3) polyoses content in 3 kinds of extracting solution is compared, result such as Fig. 2:
Steam explosion 30s and two groups of sample polysaccharide extract rates of steam explosion 60s are carried by without the 2.863% of steam explosion matched group respectively as seen from Figure 2
Rising to 5.978% and 10.377%, exceed 1.08 times and 2.62 times, test absolutely proves that employing steam explosion processes can significantly improve perfume (or spice)
Mushroom polysaccharide extract rate.
Embodiment 3: steam explosion pretreatment Herba Dendrobii
Taking Herba Dendrobii dry product, add distilled water, being dipped to its water content is 50%, with 200 DEG C, 0.8 MPa guarantor in steam-explosion jar
Pressure 60s, steam explosion process terminates rear collection material.
Embodiment 4: steam explosion pretreatment Tremella
Taking Tremella dry product, add distilled water, being dipped to its water content is 80%, with 150 DEG C, 1.2 MPa pressurizes in steam-explosion jar
120s, steam explosion process terminates rear collection material.
Embodiment 5: the steam explosion pretreatment Radix Astragali
Taking Radix Astragali sample, add distilled water, being dipped to its water content is 120%, with 220 DEG C, 1.0 MPa pressurizes in steam-explosion jar
40s, steam explosion process terminates rear collection material.
Claims (5)
1. a Chinese crude drug preprocess method, it is characterised in that comprise the steps:
(1), after Chinese crude drug being cleared up remove impurity, use and soak or spray pattern raising water content, seal after dewatering and carry out sam；
(2) adjust the Chinese crude drug after moisture and load in steam explosion device, seal, use electrical heating or direct open firing, boost to
Moment release after preset pressure, and pressurize certain time, completes steam explosion collection material.
2. the method for claim 1, it is characterised in that the moisture after described adjustment moisture is 50-250%.
3. the method for claim 1, it is characterised in that described electrical heating or directly open firing maintain the temperature at 150-
250℃。
4. the method for claim 1, it is characterised in that described pressure is 0.4-1.2MPa.
5. the method for claim 1, it is characterised in that described Chinese crude drug be Poria, Lentinus Edodes, Herba Dendrobii, the Radix Astragali or
Tremella.
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Cited By (6)
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|---|---|---|---|---|
| CN108341892A (en) * | 2018-05-09 | 2018-07-31 | 四川岚晟生物科技有限公司 | A kind of preparation method of Inonotue obliquus |
| CN108752490A (en) * | 2018-05-09 | 2018-11-06 | 四川岚晟生物科技有限公司 | A kind of preparation method of lentinan |
| CN110540604A (en) * | 2019-10-12 | 2019-12-06 | 西藏天虹科技股份有限责任公司 | Method for extracting conic gymnadenia rhizome polysaccharide |
| CN111743816A (en) * | 2019-03-29 | 2020-10-09 | 北京东方淼森生物科技有限公司 | Skin care product additive with anti-haze effect and industrial preparation method thereof |
| CN112058447A (en) * | 2020-07-24 | 2020-12-11 | 湘潭大学 | Sepiolite ore temperature and pressure transient crushing method |
| CN116808089A (en) * | 2023-06-29 | 2023-09-29 | 齐鲁工业大学(山东省科学院) | American ginseng processing method based on steam explosion process |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108341892A (en) * | 2018-05-09 | 2018-07-31 | 四川岚晟生物科技有限公司 | A kind of preparation method of Inonotue obliquus |
| CN108752490A (en) * | 2018-05-09 | 2018-11-06 | 四川岚晟生物科技有限公司 | A kind of preparation method of lentinan |
| CN111743816A (en) * | 2019-03-29 | 2020-10-09 | 北京东方淼森生物科技有限公司 | Skin care product additive with anti-haze effect and industrial preparation method thereof |
| CN110540604A (en) * | 2019-10-12 | 2019-12-06 | 西藏天虹科技股份有限责任公司 | Method for extracting conic gymnadenia rhizome polysaccharide |
| CN112058447A (en) * | 2020-07-24 | 2020-12-11 | 湘潭大学 | Sepiolite ore temperature and pressure transient crushing method |
| CN116808089A (en) * | 2023-06-29 | 2023-09-29 | 齐鲁工业大学(山东省科学院) | American ginseng processing method based on steam explosion process |
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Application publication date: 20170104 |