CN106266294A - A kind of natural skin ointment and preparation method thereof - Google Patents

A kind of natural skin ointment and preparation method thereof Download PDF

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Publication number
CN106266294A
CN106266294A CN201610851308.6A CN201610851308A CN106266294A CN 106266294 A CN106266294 A CN 106266294A CN 201610851308 A CN201610851308 A CN 201610851308A CN 106266294 A CN106266294 A CN 106266294A
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extracting solution
skin
ointment
natural skin
flos carthami
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陈建国
刘淼
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Urumqi Sunmed Yuan Biotechnology Co Ltd
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Urumqi Sunmed Yuan Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538—Schizonepeta
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention discloses a kind of natural skin ointment, this ointment includes Semen Flos Carthami, favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Semen Vitis viniferae and water.The invention also discloses the preparation method of a kind of natural skin ointment, including: use the method for ultrasonic extraction from extracting proanthocyanidin from grape seeds；The method using low-temperature cold pressing extracts safflower oil from Semen Flos Carthami；By favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae boiling, obtain the first extracting solution；By Olibanum and Myrrha boiling, obtain the second extracting solution；Procyanidin, safflower oil, the first extracting solution and the second extracting solution are mixed, after heated and boiled, keeps micro-boiling, stirring cooling to obtain.The natural skin ointment that the present invention provides has higher antiinflammatory, antibacterial and antioxidative effect, has good therapeutic effect to multiple dermatosis, and can promote skin regeneration.

Description

A kind of natural skin ointment and preparation method thereof
Technical field
The present invention relates to pharmaceutical compounding techniques field, it is more particularly related to a kind of natural skin ointment and The preparation method of its this natural skin ointment.
Background technology
Dermatosis is to occur at skin and the general name of skin accessory organ's disease.Skin is the organ that human body is maximum, skin Sick kind is the most various, and the disease that multiple internal organs occur can also have performance on skin.Cause dermopathic reason a lot, The dermatosis that such as infective agent causes, usually has certain infectiousness such as leprosy, scabies, mycosis, bacterial skin infections etc., Not only affect healthy, and raise fear and social discrimination.
What treating skin disease use was most is medicine for external use.If medicine for external use selects or improper use, the most invalid, even make Aggravation.And existing skin ointments agent mostly is antibiotic ointment, and toxic and side effects inherently wanted by antibiotic, and for mistake The crowd of quick property dermatitis, perhaps causes superinfection after using antibiotic ointment, it is often more important that, antibiotic also has drug resistance, Therefore, for dermatosiss such as allergic dermatitis, psoriasis, acnes, also not the most always pure natural, have no side effect, instant effect and not The easily medicine for external use of recurrence.
Summary of the invention
It is an object of the invention to solve at least the above, and the advantage that at least will be described later is provided.
It is a still further object of the present invention to provide a kind of natural skin ointment, this natural skin ointment is that external is coated with The drug of topical application, has preferable therapeutic effect to multiple dermatosis, has antiinflammatory, antibacterial effect, and this skin ointments agent is by multiple Chinese medicine is made, and without any chemical composition, therefore has safely, has no side effect, instant effect, is difficult to recurrence and to medicine The advantage that will not produce dependence, this ointment applies also for the symptom such as skin burn and skin trauma simultaneously.
It is a still further object of the present invention to provide the preparation method of a kind of natural skin ointment, this preparation method letter Single, and prepared a kind of natural skin ointment with multiple efficacies by plurality of Chinese.
To achieve these goals, the invention provides a kind of natural skin ointment, including following raw material:
Semen Flos Carthami, favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Portugal Grape seed and suitable quantity of water.
Safflower oil can be extracted from Semen Flos Carthami, safflower oil be mainly composed of vitamin E and linoleic acid, vitamin E There is the effect of defying age, make aging, old and feeble cell and tissue get increasingly vigorous, body immunity can be improved simultaneously, eliminate certainly By base.Linoleic acid can be to the protected effect of some skin injurys caused due to X-ray, and linoleic acid has strengthening metabolism, Strengthen the function of cell viability, it is possible to promote wound healing.
Rich in abundant procyanidin in Semen Vitis viniferae, procyanidin has non-oxidizability, eliminates free radical and defying age Effect, and senile dementia can be prevented.
Favus skin, Radix Sophorae Flavescentis have clearing away heat-damp and promoting diuresis, dispeiling pathogenic wind and removing dampness, effect of heat-clearing and toxic substances removing, can treat skin pruritus；Galla Chinensis There is effect of hemostasis removing toxic substances, treat Skin wet and rotten；The antipruritic power of Fructus Xanthii and Fructus Cnidii is strong；Herba Schizonepetae can be dispeled the wind dissipating blood stasis, broken knot Detumescence；Herba portulacae clearing away heat-damp and promoting diuresis, can removing toxic substances and promoting subsidence of swelling；Radix Angelicae Dahuricae energy pain relieving, sensible, the detumescence and apocenosis of dehumidifying, there is anti-inflammatory efficacy；Olibanum Cooperation with Myrrha has invigorating circulation of blood to dissipate blood stasis and reducing swelling and relieving pain.
The present invention is with Semen Flos Carthami, favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae, the Radix Angelicae Dahuricae, breast Perfume, Myrrha and Semen Vitis viniferae are raw material, are prepared for natural skin ointment, and this ointment combines the drug effect of each raw material, has Antiinflammatory, antibacterial effect, be widely used in the multiple dermatosis such as psoriasis, allergic dermatitis, acne, simultaneously to skin burn, The symptoms such as skin trauma also have preferable effect, beneficially the recovery regeneration of skin, have safely, have no side effect, instant effect excellent Point, and due to the middle one-tenth medicine for external use that this ointment is pure natural, control dosage that therefore need not be strict, it is to avoid western patent medicine or Person's antibiotic medicine for external use must cause the phenomenons such as secondary allergy in strict accordance with dosage, and this natural skin ointment also has good simultaneously Good skin regeneration and antioxidative ability, meet people's demand to face's image.
Present invention also offers the preparation method of a kind of natural skin ointment, comprise the following steps:
Step one, use ultrasonic extraction method from described extracting proanthocyanidin from grape seeds: Semen Vitis viniferae is carried out powder Broken, in Semen Vitis viniferae powder, add the water of 6～8 times of its weight, carry out under the power of 60～100W 10～15min ultrasonic Ripple extracts, and obtains filtrate, described filtrate is concentrated into 0.15～0.25g/mL, obtains procyanidin after filtration；
Step 2, the method for employing low-temperature cold pressing extract safflower oil from described Semen Flos Carthami: crush Semen Flos Carthami, And use deionized water that the Semen Flos Carthami after crushing is carried out moistening, the Semen Flos Carthami after moistening is placed in squeezer and squeezes, Obtain crude oil, when the temperature of described crude oil is 5～10 DEG C, described crude oil is filtered, obtains safflower oil, wherein, institute The feeding temperature stating the Semen Flos Carthami after moistening is 30～38 DEG C, and the temperature going out crude oil is 30～38 DEG C；
Step 3, by favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae boiling 8 ～15 hours, and the solution after decocting is filtered, obtain the first extracting solution；
Step 4, by Olibanum and Myrrha boiling 5～10 hours, and the solution after decocting is filtered, obtains Second extracting solution；
Step 5, by described procyanidin, described safflower oil, described first extracting solution and described second extracting solution according to Certain mass percent mixes, and after heated and boiled keeps 30min in 15 minutes under 90 DEG C of slight boiling conditions, performs stirring Cooling down operation obtains natural skin ointment.
In the preparation method of natural skin ointment of the present invention, the method for low-temperature cold pressing is used to carry from Semen Flos Carthami Take safflower oil, and combine filter at low temperature operation, extract and obtained the safflower oil that purity is high；And use the side of ultrasonic extraction Method extracts procyanidin, improves extraction ratio and extraction rate, and also ensure that in the preparation process of natural skin ointment Interpolation without chemical substance；In combination with the proportioning of each component, prepared a kind of multipurpose, many effects natural skin soft Unguentum, preparation process is simple, it is not necessary to too much man power and material, it is possible to batch production, and the cost of raw material is relatively low simultaneously, thus Greatly reduce the production cost of skin ointments agent.
Preferably, in the preparation method of described natural skin ointment, in described step 3, favus skin, Radix Sophorae Flavescentis, five The weight ratio of gall nut, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and the Radix Angelicae Dahuricae is 0.8～1.2:1.5:1～2:1:0.8:1:2: 0.5。
Preferably, in the preparation method of described natural skin ointment, in described step 3, the weight of water is described 7～8 times of favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae gross weight.
Preferably, in the preparation method of described natural skin ointment, in described step 4, Olibanum, Myrrha and water Weight ratio be 1:0.8～1.2:10.Mode Olibanum and Myrrha individually combined can give full play to the drug effect of the two, no The weakening of the two drug effect can be caused, there is effect of invigorating circulation of blood to dissipate blood stasis and reducing swelling and relieving pain.
Preferably, in the preparation method of described natural skin ointment, in described step 5, described procyanidin, The weight ratio of described safflower oil, described first extracting solution and described second extracting solution is 1:1:9:2.
The present invention at least includes following beneficial effect:
1, natural skin ointment of the present invention is made up of plurality of Chinese, combines the drug effect of each Chinese medicine, has Antiinflammatory, antibacterial effect, it is widely used in the dermatosiss such as psoriasis, allergic dermatitis, acne, can promote that wound is more simultaneously Close, it is possible to avoid the protected effect of some skin injurys that X-ray causes, and linoleic acid has strengthening metabolism, strengthens cell The function of vigor, has safely, has no side effect, the advantage of instant effect, and owing to being natural middle one-tenth medicine for external use, therefore need not be tight The control dosage of lattice, it is to avoid western patent medicine or antibiotic medicine for external use must cause secondary allergy etc. existing in strict accordance with dosage As, this natural skin ointment also has good skin regeneration and antioxidative ability simultaneously, meets people to face The demand of image.
2, with plurality of Chinese as raw material in the preparation method of natural skin ointment of the present invention, by adjusting each group The proportioning divided, has prepared the natural skin ointment of a kind of multipurpose, many effects, preparation process letter by simple technique Single, it is not necessary to too much man power and material, it is possible to batch production, the cost of raw material is relatively low simultaneously, thus greatly reduces skin The production cost of ointment.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will be by this Invention research and practice and be understood by the person skilled in the art.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, to make those skilled in the art with reference to description Word can be implemented according to this.
Should be appreciated that used herein such as " have ", " comprising " and " including " term are not precluded from one or many Other element individual or the existence of a combination thereof or interpolation.
The invention provides a kind of natural skin ointment, this natural skin ointment includes Semen Flos Carthami, favus skin, hardship Ginseng, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Semen Vitis viniferae and suitable quantity of water.
Present invention also offers the preparation method of a kind of natural skin ointment, and by following example to institute of the present invention The preparation method stated is described in detail:
<embodiment one>
(1), use the method for ultrasonic extraction from described extracting proanthocyanidin from grape seeds:
Semen Vitis viniferae is pulverized, in Semen Vitis viniferae powder, adds the water of 7 times of its weight, under the power of 80W, carry out 10 ～the ultrasonic extraction of 15min, obtain filtrate after filtration, described filtrate is concentrated into 0.2g/mL, obtains procyanidin；
(2), the method for low-temperature cold pressing is used to extract safflower oil from described Semen Flos Carthami:
Semen Flos Carthami is crushed, and uses deionized water that the Semen Flos Carthami after broken is carried out moistening, wettability be 1～ 5%, the Semen Flos Carthami after moistening is placed in squeezer and squeezes, obtain crude oil, when the temperature of described crude oil is 8 DEG C, right Described crude oil filters, and obtains safflower oil, and wherein, the feeding temperature of the Semen Flos Carthami after described moistening is 36 DEG C, goes out crude oil Temperature be 36 DEG C；
(3) the first extracting solution, is prepared:
By favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae boiling 10 hours, with And the solution after decocting is filtered, obtain the first extracting solution；Favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, cnidium monnieri Son, the weight ratio of Herba portulacae and the Radix Angelicae Dahuricae are 1:1.5:1:1:0.8:1:2:0.5, the weight of water be favus skin, Radix Sophorae Flavescentis, five times 7.5 times of son, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae gross weight.
(4) the second extracting solution, is prepared:
By Olibanum and Myrrha boiling 8 hours, and the solution after decocting is filtered, obtain the second extracting solution； The weight ratio of Olibanum, Myrrha and water is 1:1:10；
(5) natural skin ointment, is prepared:
By described procyanidin, described safflower oil, described first extracting solution and described second extracting solution according to certain Mass percent mixes, and after heated and boiled keeps 30min in 15 minutes under 90 DEG C of slight boiling conditions, performs stirring cooling behaviour Make to obtain natural skin ointment, described procyanidin, described safflower oil, described first extracting solution and described second extracting solution Weight ratio be 1:1:9:2.
<embodiment two>
(1), use the method for ultrasonic extraction from described extracting proanthocyanidin from grape seeds:
Semen Vitis viniferae is pulverized, in Semen Vitis viniferae powder, adds the water of 6 times of its weight, carry out under the power of 60W The ultrasonic extraction of 15min, obtains filtrate, described filtrate is concentrated into 0.25g/mL, obtains procyanidin after filtration；
(2), the method for low-temperature cold pressing is used to extract safflower oil from described Semen Flos Carthami:
Semen Flos Carthami is crushed, and uses deionized water that the Semen Flos Carthami after crushing is carried out moistening, it is ensured that wettability is 1 ～10%, the Semen Flos Carthami after moistening is placed in squeezer and squeezes, obtain crude oil, when the temperature of described crude oil is 10 DEG C Time, described crude oil is filtered, obtains safflower oil, wherein, the feeding temperature of the Semen Flos Carthami after described moistening is 30 DEG C, goes out The temperature of crude oil is 38 DEG C；
(3) the first extracting solution, is prepared:
By favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae boiling 8 hours, with And the solution after decocting is filtered, obtain the first extracting solution；Favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, cnidium monnieri Son, the weight ratio of Herba portulacae and the Radix Angelicae Dahuricae are 0.8:1.5:1:1:0.8:1:2:0.5, the weight of water be favus skin, Radix Sophorae Flavescentis, five times 7 times of son, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae gross weight；
(4) the second extracting solution, is prepared:
By Olibanum and Myrrha boiling 5 hours, and the solution after decocting is filtered, obtain the second extracting solution； The weight ratio of Olibanum, Myrrha and water is 1:0.8:10；
(5) natural skin ointment, is prepared:
By described procyanidin, described safflower oil, described first extracting solution and described second extracting solution according to certain Mass percent mixes, and after heated and boiled keeps 30min in 15 minutes under 90 DEG C of slight boiling conditions, performs stirring cooling behaviour Make to obtain natural skin ointment, described procyanidin, described safflower oil, described first extracting solution and described second extracting solution Weight ratio be 1:1:9:2.
<embodiment three>
(1), use the method for ultrasonic extraction from described extracting proanthocyanidin from grape seeds:
Semen Vitis viniferae is pulverized, in Semen Vitis viniferae powder, adds the water of 8 times of its weight, carry out under the power of 100W The ultrasonic extraction of 10min, obtains filtrate, described filtrate is concentrated into 0.15g/mL, obtains procyanidin after filtration；
(2), the method for low-temperature cold pressing is used to extract safflower oil from described Semen Flos Carthami:
Semen Flos Carthami is crushed, and uses deionized water that the Semen Flos Carthami after broken is carried out moistening, wettability be 3～ 8%, the Semen Flos Carthami after moistening is placed in squeezer and squeezes, obtain crude oil, when the temperature of described crude oil is 5 DEG C, right Described crude oil filters, and obtains safflower oil, and wherein, the feeding temperature of the Semen Flos Carthami after described moistening is 38 DEG C, goes out crude oil Temperature be 30 DEG C；
(3) the first extracting solution, is prepared:
By favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae boiling 15 hours, with And the solution after decocting is filtered, obtain the first extracting solution；Favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, cnidium monnieri Son, the weight ratio of Herba portulacae and the Radix Angelicae Dahuricae are 1.2:1.5:2:1:0.8:1:2:0.5, the weight of water be described favus skin, Radix Sophorae Flavescentis, 8 times of Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae gross weight；
(4) the second extracting solution, is prepared:
By Olibanum and Myrrha boiling 10 hours, and the solution after decocting is filtered, obtain the second extracting solution； The weight ratio of Olibanum, Myrrha and water is 1:1.2:10；
(5) natural skin ointment, is prepared:
By described procyanidin, described safflower oil, described first extracting solution and described second extracting solution according to certain Mass percent mixes, and after heated and boiled keeps 30min in 15 minutes under 90 DEG C of slight boiling conditions, performs stirring cooling behaviour Making to obtain natural skin ointment, the weight ratio of procyanidin, safflower oil, the first extracting solution and the second extracting solution is 1:1: 9:2。
In order to verify the therapeutic effect of the natural skin ointment described in above-described embodiment, by natural skin of the present invention Skin ointment imposes on the affected part suffering from various dermopathic patients respectively, patient's totally 200 example, and using method is: external is coated with and puts on the skin, and one Day 2～3 times, 7 days is a course for the treatment of, and therapeutic effect refers to table one, and other diseases in table one include skin trauma, burn etc..
Observation of curative effect table after table one treatment
Disease Case load Cure number Effectively number of cases Invalid number of cases Cure rate Effective percentage
Psoriasis 25 24 0 1 96% 99.96%
Tinea manus and pedis 32 28 3 1 87.50% 96.88%
Tinea versicolor 30 26 3 1 86.67% 96.67%
Neurodermatitis 29 27 2 0 93.11% 100%
Allergic dermatitis 26 24 2 0 92.31% 100%
De-property dermatitis of overflowing 18 18 0 0 100% 100%
Acne 27 25 1 1 92.60% 96.30%
Other 43 38 3 2 88.37% 95.35%
230 210 14 6 91.30% 97.39%
Typical example:
Case 1: certain man, 21 years old, the longest acne, and spread all over each position of face, and infect, and with pruritus And pain, the recovery from illness in 14 days of the natural skin ointment of the coating present invention, do not recur.
Case 2: certain man, 40 years old, on arm, many places suffered from psoriasis, and 10 years as long as, the natural skin of the coating present invention The recovery from illness in 14 days of skin ointment, does not recurs.
Case 3: certain female, 30 years old, suffers from allergic dermatitis on the face, existing 10 years medical histories, the natural skin of the coating present invention Ointment recovery from illness in 7 days, does not recurs, and after healing, facial skin is the most soft.
Although embodiment of the present invention are disclosed as above, but it is not restricted in description and embodiment listed Using, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily Realizing other amendment, therefore under the general concept limited without departing substantially from claim and equivalency range, the present invention does not limit In specific details with shown here as the embodiment with description.

Claims (6)

1. a natural skin ointment, it is characterised in that include following raw material:
Semen Flos Carthami, favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae, the Radix Angelicae Dahuricae, Olibanum, Myrrha, Semen Vitis viniferae And suitable quantity of water.
2. the preparation method of a natural skin ointment as claimed in claim 1, it is characterised in that comprise the following steps:
Step one, use ultrasonic extraction method from described extracting proanthocyanidin from grape seeds: Semen Vitis viniferae is pulverized, to Semen Vitis viniferae powder adds the water of 6～8 times of its weight, under the power of 60～100W, carries out the ultrasound wave of 10～15min carry Take, obtain filtrate after filtration, described filtrate is concentrated into 0.15～0.25g/mL, obtains procyanidin；
Step 2, the method for employing low-temperature cold pressing extract safflower oil from described Semen Flos Carthami: crush Semen Flos Carthami, and make With water, the Semen Flos Carthami after crushing is carried out moistening, the Semen Flos Carthami after moistening is placed in squeezer and squeezes, obtain crude oil, when When the temperature of described crude oil is 5～10 DEG C, described crude oil is filtered, obtains safflower oil, wherein, red after described moistening The feeding temperature of flower seed is 30～38 DEG C, and the temperature going out crude oil is 30～38 DEG C；
Step 3, by favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae boiling 8～15 Hour, and the solution after decocting is filtered, obtain the first extracting solution；
Step 4, by Olibanum and Myrrha boiling 5～10 hours, and the solution after decocting is filtered, obtains second Extracting solution；
Step 5, by described procyanidin, described safflower oil, described first extracting solution and described second extracting solution according to necessarily Mass percent mix, after heated and boiled 15 minutes keeps 30min under 90 DEG C of slight boiling conditions, perform stirring cooling Operation obtains natural skin ointment.
3. the preparation method of natural skin ointment as claimed in claim 2, it is characterised in that in described step 3, tinea alba The weight ratio of skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and the Radix Angelicae Dahuricae is 0.8～1.2:1.5:1～2: 1:0.8:1:2:0.5。
4. the preparation method of natural skin ointment as claimed in claim 2, it is characterised in that in described step 3, water Weight is 7～8 times of described favus skin, Radix Sophorae Flavescentis, Galla Chinensis, Fructus Xanthii, Herba Schizonepetae, Fructus Cnidii, Herba portulacae and Radix Angelicae Dahuricae gross weight.
5. the preparation method of natural skin ointment as claimed in claim 2, it is characterised in that in described step 4, Olibanum, The weight ratio of Myrrha and water is 1:0.8～1.2:10.
6. the preparation method of natural skin ointment as claimed in claim 2, it is characterised in that in described step 5, described The weight ratio of procyanidin, described safflower oil, described first extracting solution and described second extracting solution is 1:1:9:2.
CN201610851308.6A 2016-09-27 2016-09-27 A kind of natural skin ointment and preparation method thereof Pending CN106266294A (en)

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CN109260378A (en) * 2018-10-10 2019-01-25 曲凤堂 A kind of external medicinal liquid for treating burn and scald
CN109350716A (en) * 2018-09-30 2019-02-19 赵升瑞 Pox-eliminating whitening cream
CN109512944A (en) * 2019-01-21 2019-03-26 重庆市中医院 A kind of pair of yellow detoxification tincture and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109350716A (en) * 2018-09-30 2019-02-19 赵升瑞 Pox-eliminating whitening cream
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CN109512944A (en) * 2019-01-21 2019-03-26 重庆市中医院 A kind of pair of yellow detoxification tincture and preparation method thereof

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Application publication date: 20170104