CN106266159A - A kind of for preoperative disinfectant solution - Google Patents

A kind of for preoperative disinfectant solution Download PDF

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Publication number
CN106266159A
CN106266159A CN201510331446.7A CN201510331446A CN106266159A CN 106266159 A CN106266159 A CN 106266159A CN 201510331446 A CN201510331446 A CN 201510331446A CN 106266159 A CN106266159 A CN 106266159A
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parts
preoperative
disinfectant solution
radix
herba
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CN201510331446.7A
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杨风英
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Abstract

The open one of the present invention, for preoperative disinfectant solution, is become by following raw material medicaments in part by weight array: Cortex Cinnamomi 5-10 part, Radix Scutellariae 3-7 part, Herba Asari 10-20 part, Radix Glycyrrhizae 5-15 part, Radix Angelicae Sinensis 5-15 part, Fructus Cnidii 1-2 part, Herba Houttuyniae 10-15 part, Folium sophorae 10-15 part, Semen Cassiae 5-10 part, Fructus Quisqualis 5-10 part, Cortex Magnoliae Officinalis 5-10 part, redistilled water 70-100 part.The drug matching of the present invention is reasonable, has worked in coordination with antimicrobial antiphlogistic, sterilizing effect;Each crude drug is cheap and easy to get, and the product made is useful to human body, can be the most commonly used.

Description

A kind of for preoperative disinfectant solution
Technical field
The present invention relates to surgery operating technology field, specifically a kind of for preoperative disinfectant solution.
Background technology
The sterilization of the preoperative hands of surgery is the important measures of prevention of postoperative infection, washes one's hands removing on hand by disinfectant solution All bacterium of staying temporarily, reduce permanent bacterium and reach the requirement of nearly aseptic condition to minimum level, maintain longer pressing down Bacterium effect, prevents antibacterial to be transferred to patient's operative site from staff's hands, is that prevention exogenous infection is the simplest Single most efficient method.
At present, the bubble hand sanitizing fluid types of medicines that each hospital operating room uses is more, and without unified standard.Hospital Usual disinfectant solution has 75% ethanol, geramine, chlohexidine and other disinfectant preparation of Ministry of Public Health registration approval. But there is the defect that effect is not ideal enough or price is higher in existing disinfectant solution, and Medical antiseptic solution is as often The necessary article used, it is necessary to research has the product that Disinfection Effect high-efficient and lasting, price are relatively low.
Along with the research of Chinese herbal medicine is deeply changed by modern medicine, the range of application of Chinese herbal medicine gradually expands, such as Patent of invention CN 102579302 B discloses a kind of handwashing liquid for pre-operation sterilization, and it is by following weight The material of proportioning is made: CitrusaurantiumL.Var.amara Engl. 5-10 part, Cortex Phellodendri 5-15 part, Herba Scutellariae Barbatae 1-5 part, Radix Bupleuri 3-8 part, Fructus Cnidii 0.1-0.5 part, Herba Ecliptae 3-10 part, Pericarpium Citri Reticulatae 5-10 part, Cortex Cinnamomi 3-8 part, Herba Thesii 5-10 Part, Herba Asari 10-20 part and water 50-100 part;The open one of patent of invention CN 103520455 A is used for The handwashing liquid of pre-operation sterilization, it is made up by weight of following bulk drugs: Eriocheir sinensis 7 10 parts, tiger tail 15 parts of orchid, Chloranthus japonicusSieb. 15 parts, Aralia decaisneana Hance 20 parts, Herba Monochoriae Korsakowii 10 parts, Flos Woodfordiae Fruticosae 10 parts, Herba malachii aquatici 5 Part, Herba Epilobii Angustifoii 15 parts, HERBA VERONICAE DILATATAE 15 parts, Herba indigoferae bungeanae 10 parts, Herba Tricyrtis Pilosae 15 parts and asparagus 10 parts. Though above-mentioned formula has disinfective action, but fractions has certain impact to human body, and renal function is had by such as Herba Asari Adverse effect, and Cortex Cinnamomi is the property medicine of a warm nature, should not commonly use, Herba malachii aquatici is cold in nature for another example, especially to weakness of the spleen and stomach person Unhelpful, unfavorable to the doctor often performed the operation.
Summary of the invention
The technical problem to be solved is the defect for prior art, it is provided that a kind of for surgery hands Preoperative disinfectant solution.
To achieve these goals, the present invention is achieved by the following technical solutions:
A kind of for preoperative disinfectant solution, following raw material medicaments in part by weight array become: Cortex Cinnamomi 5-10 Part, Radix Scutellariae 3-7 part, Herba Asari 10-20 part, Radix Glycyrrhizae 5-15 part, Radix Angelicae Sinensis 5-15 part, Fructus Cnidii 1-2 part, Herba Houttuyniae 10-15 part, Folium sophorae 10-15 part, Semen Cassiae 5-10 part, Fructus Quisqualis 5-10 part, Cortex Magnoliae Officinalis 5-10 Part, redistilled water 70-100 part.
Preferably, described one is used for preoperative disinfectant solution by following raw material medicaments in part by weight array Become: Cortex Cinnamomi 8 parts, Radix Scutellariae 4 parts, Herba Asari 15 parts, 10 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 10 parts, Fructus Cnidii 1.5 parts, Herba Houttuyniae 12 parts, Folium sophorae 12 parts, Semen Cassiae 7 parts, Fructus Quisqualis 8 parts, Cortex Magnoliae Officinalis 8 parts, redistilled water 85 Part.
Described a kind of preparation method for preoperative disinfectant solution is: by Cortex Cinnamomi, Radix Scutellariae, Herba Asari, Radix Glycyrrhizae, Radix Angelicae Sinensis, Fructus Cnidii, Herba Houttuyniae, Folium sophorae, Semen Cassiae, Fructus Quisqualis, Cortex Magnoliae Officinalis carry out ultra micro respectively Pulverize, obtain each crude drug fine powder, after mixing each crude drug fine powder by weight, be equipped with the close of redistilled water Close in container, under the water-bath of 90-100 DEG C, heat 2-3h, filter, collect filtrate, concentrate the filtrate to former The 3/5 of liquid, sterilizing is placed in watering can and get final product.
The granularity of described crude drug fine powder is 10-15um.
Preferably, described a kind of in the preparation method of preoperative disinfectant solution, at 90-100 DEG C Supersound process, supersonic frequency 40KHz, power 180W is carried out while water-bath.
Effect of each crude drug in the present invention: Herba Asari, anti inflammatory immunity, improves metabolism, antibacterial, antipyretic Analgesia, expelling wind and cold;Cortex Cinnamomi, antibiotic and sterilizing, complement sun, warming the spleen and stomach, promoting blood circulation;Radix Scutellariae, antibacterial, Hemostasis, heat clearing and damp drying, eliminating fire and detoxication;Radix Glycyrrhizae, detoxify, regulate body's immunity, arrhythmia, Coordinating the actions of various ingredients in a prescription;Radix Angelicae Sinensis, anti-inflammatory and antalgic, antibacterial, blood circulation promoting and enriching, protection kidney;Fructus Cnidii, antibacterial, anti- Arrhythmia, warming the kidney to invigorate YANG, dispelling wind for relieving itching;Herba Houttuyniae, antibacterial, antiviral, raising immunity of organisms, Heat-clearing and toxic substances removing, subside a swelling, dehumidify;Folium sophorae, improving eyesight, controls vexed vexed unrest;Semen Cassiae, antibacterial blood pressure lowering, makes Gentleman, clearing away heat to improve acuity of vision;Antibacterial, heat clearing away;Circulation of qi promoting removing dampness, warming middle-JIAO to relieve pain, lowering the adverse QI to relieve asthma, antibacterial, alleviation Striped muscle is tetanic.
Beneficial effects of the present invention: drug matching is reasonable, has worked in coordination with antimicrobial antiphlogistic, sterilizing effect;Respectively Crude drug is cheap and easy to get, and the product made is useful to human body, can be the most commonly used.
Detailed description of the invention
The present invention is expanded on further in conjunction with the embodiments, does not constitute and the scope of the present invention is limited.
Embodiment 1
A kind of for preoperative disinfectant solution, following raw material medicaments in part by weight array become: Cortex Cinnamomi 5 parts, Radix Scutellariae 3 parts, Herba Asari 10 parts, 5 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 5 parts, Fructus Cnidii 1 part, Herba Houttuyniae 10 parts, Chinese scholartree Leaves 10 parts, Semen Cassiae 5 parts, Fructus Quisqualis 5 parts, Cortex Magnoliae Officinalis 5 parts, redistilled water 70 parts.
Described a kind of preparation method for preoperative disinfectant solution is: by Cortex Cinnamomi, Radix Scutellariae, Herba Asari, Radix Glycyrrhizae, Radix Angelicae Sinensis, Fructus Cnidii, Herba Houttuyniae, Folium sophorae, Semen Cassiae, Fructus Quisqualis, Cortex Magnoliae Officinalis carry out ultra micro respectively Pulverize, obtain each crude drug fine powder, after mixing each crude drug fine powder by weight, be equipped with the close of redistilled water Close in container, under the water-bath of 90 DEG C, heat 2h, filter, collect filtrate, concentrate the filtrate to the 3/5 of stock solution, Sterilizing is placed in watering can and get final product.
Embodiment 2
A kind of for preoperative disinfectant solution, following raw material medicaments in part by weight array become: Cortex Cinnamomi 10 parts, Radix Scutellariae 7 parts, Herba Asari 20 parts, 15 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 15 parts, Fructus Cnidii 2 parts, Herba Houttuyniae 15 parts, Folium sophorae 15 parts, Semen Cassiae 10 parts, Fructus Quisqualis 10 parts, Cortex Magnoliae Officinalis 10 parts, redistilled water 100 parts.
Described a kind of preparation method for preoperative disinfectant solution is: by Cortex Cinnamomi, Radix Scutellariae, Herba Asari, Radix Glycyrrhizae, Radix Angelicae Sinensis, Fructus Cnidii, Herba Houttuyniae, Folium sophorae, Semen Cassiae, Fructus Quisqualis, Cortex Magnoliae Officinalis carry out ultra micro respectively Pulverize, obtain each crude drug fine powder, after mixing each crude drug fine powder by weight, be equipped with the close of redistilled water Close in container, under the water-bath of 100 DEG C, heat 3h, filter, collect filtrate, concentrate the filtrate to stock solution 3/5, sterilizing is placed in watering can and get final product.
Embodiment 3
A kind of for preoperative disinfectant solution, following raw material medicaments in part by weight array become: Cortex Cinnamomi 5-10 Part, Radix Scutellariae 6 parts, Herba Asari 15 parts, 10 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 12 parts, Fructus Cnidii 1.5 parts, Herba Houttuyniae 12 Part, Folium sophorae 12 parts, Semen Cassiae 7 parts, Fructus Quisqualis 6 parts, Cortex Magnoliae Officinalis 7 parts, redistilled water 100 parts.
Described a kind of preparation method for preoperative disinfectant solution is: by Cortex Cinnamomi, Radix Scutellariae, Herba Asari, Radix Glycyrrhizae, Radix Angelicae Sinensis, Fructus Cnidii, Herba Houttuyniae, Folium sophorae, Semen Cassiae, Fructus Quisqualis, Cortex Magnoliae Officinalis carry out ultra micro respectively Pulverize, obtain each crude drug fine powder, after mixing each crude drug fine powder by weight, be equipped with the close of redistilled water Close in container, under the water-bath of 100 DEG C, heat 3h, filter, collect filtrate, concentrate the filtrate to stock solution 3/5, sterilizing is placed in watering can and get final product.
Experimental example
Bacteriostatic test
After deliberation, the pathogenic bacteria that hand most frequently contacts is will he in staphylococcus aureus (ATCC6538) and Song Salmonella (ATCC25931), therefore if able to carry out disinfection for both pathogenic bacterias, then can be preferably in operation Period plays a protective role.
Filter paper enzyme classical in this area is used to carry out bacteriostatic test, wherein:
1. material
1.1 for examination strain
Staphylococcus aureus (ATCC6538) is purchased from Chuan Xiang bio tech ltd, Shanghai, will Hayes in Song Bacterium (ATCC25931) is purchased from Ai Yan bio tech ltd, Shanghai.
1.2 culture fluid
Nutrient agar and nutrient broth, purchased from Shanghai Yan Yu commerce and trade company limited.
1.3 test method
Staphylococcus aureus (ATCC6538) and Shigella sonnei (ATCC25931) are inoculated in agar In flat board nutritional solution plane, uniformly gather during inoculation.Tweezer aseptic circular filter paper sheet, sprays in embodiment 1 The handwashing liquid of preparation, to complete wetting, is attached in the agar plate nutritional solution plane of inoculated bacteria.By agar Flat board is placed in the incubator of 37 DEG C, incubation 24 hours.Measure the diameter of antibacterial ring.Measure and be averaged for 3 times Value.
1.4 result
The average diameter of the antibacterial ring of staphylococcus aureus is 12.26mm, Shigella sonnei ring antibacterial The average diameter of ring is 8.38mm.
Test result indicate that the handwashing liquid of the present invention has obvious Disinfection Effect.

Claims (5)

1. one kind is used for preoperative disinfectant solution, it is characterised in that: by following raw material medicaments in part by weight number Composition: Cortex Cinnamomi 5-10 part, Radix Scutellariae 3-7 part, Herba Asari 10-20 part, Radix Glycyrrhizae 5-15 part, Radix Angelicae Sinensis 5-15 part, Fructus Cnidii 1-2 part, Herba Houttuyniae 10-15 part, Folium sophorae 10-15 part, Semen Cassiae 5-10 part, Fructus Quisqualis 5-10 Part, Cortex Magnoliae Officinalis 5-10 part, redistilled water 70-100 part.
One the most according to claim 1 is used for preoperative disinfectant solution, it is characterised in that: by Following raw material medicaments in part by weight array become: Cortex Cinnamomi 8 parts, Radix Scutellariae 4 parts, Herba Asari 15 parts, 10 parts of Radix Glycyrrhizae, Radix Angelicae Sinensis 10 parts, Fructus Cnidii 1.5 parts, Herba Houttuyniae 12 parts, Folium sophorae 12 parts, Semen Cassiae 7 parts, Fructus Quisqualis 8 parts, Cortex Magnoliae Officinalis 8 parts, redistilled water 85 parts.
A kind of preparation method for preoperative disinfectant solution the most according to claim 1, it is special Levy and be: by Cortex Cinnamomi, Radix Scutellariae, Herba Asari, Radix Glycyrrhizae, Radix Angelicae Sinensis, Fructus Cnidii, Herba Houttuyniae, Folium sophorae, Semen Cassiae Son, Fructus Quisqualis, Cortex Magnoliae Officinalis carry out micronizing respectively, obtain each crude drug fine powder, mix each former by weight It is equipped with in the hermetic container of redistilled water after material medicine fine powder, under the water-bath of 90-100 DEG C, heats 2-3h, mistake Filter, collects filtrate, concentrates the filtrate to the 3/5 of stock solution, and sterilizing is placed in watering can and get final product.
A kind of preparation method for preoperative disinfectant solution the most according to claim 1, it is special Levy and be: the granularity of described crude drug fine powder is 10-15um.
A kind of preparation method for preoperative disinfectant solution the most according to claim 1, it is special Levy and be: while 90-100 DEG C of water-bath, carry out supersound process, supersonic frequency 40KHz, power 180W.
CN201510331446.7A 2015-06-12 2015-06-12 A kind of for preoperative disinfectant solution Pending CN106266159A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109316634A (en) * 2018-10-23 2019-02-12 江苏耐雀生物工程技术有限公司 A kind of natural bacteriostatic midwifery gel and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109316634A (en) * 2018-10-23 2019-02-12 江苏耐雀生物工程技术有限公司 A kind of natural bacteriostatic midwifery gel and preparation method thereof

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Application publication date: 20170104