CN106266106A - The Chinese medicine preparation for the treatment of atrophic gastritis - Google Patents
The Chinese medicine preparation for the treatment of atrophic gastritis Download PDFInfo
- Publication number
- CN106266106A CN106266106A CN201610804176.1A CN201610804176A CN106266106A CN 106266106 A CN106266106 A CN 106266106A CN 201610804176 A CN201610804176 A CN 201610804176A CN 106266106 A CN106266106 A CN 106266106A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- fructus
- chinese medicine
- medicine preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 208000016644 chronic atrophic gastritis Diseases 0.000 title claims abstract description 16
- 208000004300 Atrophic Gastritis Diseases 0.000 title claims abstract description 15
- 208000036495 Gastritis atrophic Diseases 0.000 title claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 16
- 241000628997 Flos Species 0.000 claims abstract description 10
- 241000218176 Corydalis Species 0.000 claims abstract description 9
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 9
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 9
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000007788 liquid Substances 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 238000009835 boiling Methods 0.000 claims description 8
- 230000033228 biological regulation Effects 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 claims description 4
- 239000012535 impurity Substances 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- 238000002386 leaching Methods 0.000 claims 1
- 210000000952 spleen Anatomy 0.000 abstract description 36
- 230000000694 effects Effects 0.000 abstract description 22
- 238000010792 warming Methods 0.000 abstract description 13
- 238000005728 strengthening Methods 0.000 abstract description 6
- 230000000202 analgesic effect Effects 0.000 abstract description 5
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 5
- 206010003549 asthenia Diseases 0.000 abstract description 4
- 230000036039 immunity Effects 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 abstract description 2
- 230000005764 inhibitory process Effects 0.000 abstract description 2
- 230000002787 reinforcement Effects 0.000 abstract description 2
- 210000002784 stomach Anatomy 0.000 description 17
- 208000002193 Pain Diseases 0.000 description 14
- 206010062717 Increased upper airway secretion Diseases 0.000 description 12
- 208000026435 phlegm Diseases 0.000 description 12
- 206010011224 Cough Diseases 0.000 description 10
- 206010047700 Vomiting Diseases 0.000 description 10
- 210000004072 lung Anatomy 0.000 description 9
- 201000006549 dyspepsia Diseases 0.000 description 8
- 235000013305 food Nutrition 0.000 description 8
- 230000006870 function Effects 0.000 description 8
- 206010012735 Diarrhoea Diseases 0.000 description 7
- 239000000796 flavoring agent Substances 0.000 description 7
- 235000019634 flavors Nutrition 0.000 description 7
- 230000001737 promoting effect Effects 0.000 description 7
- 230000008673 vomiting Effects 0.000 description 7
- 230000036528 appetite Effects 0.000 description 6
- 235000019789 appetite Nutrition 0.000 description 6
- 210000000481 breast Anatomy 0.000 description 6
- 235000009508 confectionery Nutrition 0.000 description 6
- 229930182470 glycoside Natural products 0.000 description 6
- 150000002338 glycosides Chemical class 0.000 description 6
- 210000001015 abdomen Anatomy 0.000 description 5
- 208000019790 abdominal distention Diseases 0.000 description 5
- 108010019077 beta-Amylase Proteins 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 230000029087 digestion Effects 0.000 description 5
- 210000002216 heart Anatomy 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 206010000077 Abdominal mass Diseases 0.000 description 4
- 206010000087 Abdominal pain upper Diseases 0.000 description 4
- FBMORZZOJSDNRQ-GLQYFDAESA-N Atractylenolide III Chemical compound C=C([C@@H]1C2)CCC[C@]1(C)C[C@@]1(O)C2=C(C)C(=O)O1 FBMORZZOJSDNRQ-GLQYFDAESA-N 0.000 description 4
- 108090000637 alpha-Amylases Proteins 0.000 description 4
- 210000000038 chest Anatomy 0.000 description 4
- 230000004087 circulation Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 208000001848 dysentery Diseases 0.000 description 4
- 239000003172 expectorant agent Substances 0.000 description 4
- 230000003419 expectorant effect Effects 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 3
- 229920000945 Amylopectin Polymers 0.000 description 3
- 229920000856 Amylose Polymers 0.000 description 3
- 208000000059 Dyspnea Diseases 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- 206010019233 Headaches Diseases 0.000 description 3
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 3
- 206010033557 Palpitations Diseases 0.000 description 3
- 206010036790 Productive cough Diseases 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- 208000006673 asthma Diseases 0.000 description 3
- 206010061428 decreased appetite Diseases 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 description 3
- 229960004949 glycyrrhizic acid Drugs 0.000 description 3
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 description 3
- 235000019410 glycyrrhizin Nutrition 0.000 description 3
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- SYTGUXGLBXTALU-UHFFFAOYSA-N 2h-1,4-oxazine-3-carboxylic acid Chemical compound OC(=O)C1=NC=COC1 SYTGUXGLBXTALU-UHFFFAOYSA-N 0.000 description 2
- KSDSYIXRWHRPMN-UHFFFAOYSA-N 4'-O-beta-D-Galactopyranoside-6''-p-Coumaroylprunin-4',5,7-Trihydroxyflavanone Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(C2OC3=CC(O)=CC(O)=C3C(=O)C2)C=C1 KSDSYIXRWHRPMN-UHFFFAOYSA-N 0.000 description 2
- NESFDGDRYVANBC-UHFFFAOYSA-N 6-(hydroxymethyl)pyridin-3-ol Chemical compound OCC1=CC=C(O)C=N1 NESFDGDRYVANBC-UHFFFAOYSA-N 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 2
- 241000756943 Codonopsis Species 0.000 description 2
- FBMORZZOJSDNRQ-UHFFFAOYSA-N Demethoxy,B,HCl-Adriamycin Natural products C1C2C(=C)CCCC2(C)CC2(O)C1=C(C)C(=O)O2 FBMORZZOJSDNRQ-UHFFFAOYSA-N 0.000 description 2
- 229920001353 Dextrin Polymers 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- 206010016807 Fluid retention Diseases 0.000 description 2
- 239000004378 Glycyrrhizin Substances 0.000 description 2
- 206010019909 Hernia Diseases 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- DEMKZLAVQYISIA-ONJCETCRSA-N Liquiritin Natural products O([C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)c1ccc([C@@H]2Oc3c(C(=O)C2)ccc(O)c3)cc1 DEMKZLAVQYISIA-ONJCETCRSA-N 0.000 description 2
- DEMKZLAVQYISIA-UHFFFAOYSA-N Liquirtin Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(C2OC3=CC(O)=CC=C3C(=O)C2)C=C1 DEMKZLAVQYISIA-UHFFFAOYSA-N 0.000 description 2
- 206010054949 Metaplasia Diseases 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- OBIOZWXPDBWYHB-UHFFFAOYSA-N Nobiletin Natural products C1=CC(OC)=CC=C1C1=C(OC)C(=O)C2=C(OC)C(OC)=C(OC)C(OC)=C2O1 OBIOZWXPDBWYHB-UHFFFAOYSA-N 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 206010067171 Regurgitation Diseases 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 230000001166 anti-perspirative effect Effects 0.000 description 2
- 239000003213 antiperspirant Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 208000013219 diaphoresis Diseases 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 210000004907 gland Anatomy 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- GBRZTUJCDFSIHM-KRWDZBQOSA-N licoricidin Chemical compound C1([C@@H]2COC=3C=C(O)C(CC=C(C)C)=C(C=3C2)OC)=CC=C(O)C(CC=C(C)C)=C1O GBRZTUJCDFSIHM-KRWDZBQOSA-N 0.000 description 2
- DEMKZLAVQYISIA-ZRWXNEIDSA-N liquiritin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C([C@H]2OC3=CC(O)=CC=C3C(=O)C2)C=C1 DEMKZLAVQYISIA-ZRWXNEIDSA-N 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 230000015689 metaplastic ossification Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- MRIAQLRQZPPODS-UHFFFAOYSA-N nobiletin Chemical compound C1=C(OC)C(OC)=CC=C1C1=CC(=O)C2=C(OC)C(OC)=C(OC)C(OC)=C2O1 MRIAQLRQZPPODS-UHFFFAOYSA-N 0.000 description 2
- YQUVCSBJEUQKSH-UHFFFAOYSA-N protochatechuic acid Natural products OC(=O)C1=CC=C(O)C(O)=C1 YQUVCSBJEUQKSH-UHFFFAOYSA-N 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- GSZUGBAEBARHAW-UHFFFAOYSA-N sophoraflavone B Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(C=2OC3=CC(O)=CC=C3C(=O)C=2)C=C1 GSZUGBAEBARHAW-UHFFFAOYSA-N 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- KCDXJAYRVLXPFO-UHFFFAOYSA-N syringaldehyde Chemical compound COC1=CC(C=O)=CC(OC)=C1O KCDXJAYRVLXPFO-UHFFFAOYSA-N 0.000 description 2
- QJVXKWHHAMZTBY-GCPOEHJPSA-N syringin Chemical compound COC1=CC(\C=C\CO)=CC(OC)=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 QJVXKWHHAMZTBY-GCPOEHJPSA-N 0.000 description 2
- QJVXKWHHAMZTBY-KSXIZUIISA-N syringin Natural products COc1cc(C=CCO)cc(OC)c1O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O QJVXKWHHAMZTBY-KSXIZUIISA-N 0.000 description 2
- -1 triterpenoid compound Chemical class 0.000 description 2
- WKOLLVMJNQIZCI-UHFFFAOYSA-N vanillic acid Chemical compound COC1=CC(C(O)=O)=CC=C1O WKOLLVMJNQIZCI-UHFFFAOYSA-N 0.000 description 2
- TUUBOHWZSQXCSW-UHFFFAOYSA-N vanillic acid Natural products COC1=CC(O)=CC(C(O)=O)=C1 TUUBOHWZSQXCSW-UHFFFAOYSA-N 0.000 description 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
- 239000001100 (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Substances 0.000 description 1
- JVAZJLFFSJARQM-RMPHRYRLSA-N (2r,3r,4s,5s,6r)-2-hexoxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound CCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O JVAZJLFFSJARQM-RMPHRYRLSA-N 0.000 description 1
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 description 1
- SMNDYUVBFMFKNZ-UHFFFAOYSA-N 2-furoic acid Chemical compound OC(=O)C1=CC=CO1 SMNDYUVBFMFKNZ-UHFFFAOYSA-N 0.000 description 1
- ABKPQICIFGNRAA-YCRPTBBLSA-N 5-[(e)-3-[3,5-dimethoxy-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-enoxy]-3-methyl-5-oxo-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoic acid Chemical compound C=1C(OC)=C(O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C(OC)=CC=1\C=C\COC(=O)CC(C)(CC(O)=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O ABKPQICIFGNRAA-YCRPTBBLSA-N 0.000 description 1
- DLHXRDUXNVEIEY-UHFFFAOYSA-N 7-Methylcoumarin Chemical compound C1=CC(=O)OC2=CC(C)=CC=C21 DLHXRDUXNVEIEY-UHFFFAOYSA-N 0.000 description 1
- CJIJXIFQYOPWTF-UHFFFAOYSA-N 7-hydroxycoumarin Natural products O1C(=O)C=CC2=CC(O)=CC=C21 CJIJXIFQYOPWTF-UHFFFAOYSA-N 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- OQYBLUDOOFOBPO-UHFFFAOYSA-N Asterolide Natural products C1C2C(=C)CCCC2(C)CC2C1=C(C)C(=O)O2 OQYBLUDOOFOBPO-UHFFFAOYSA-N 0.000 description 1
- OQYBLUDOOFOBPO-KCQAQPDRSA-N Atractylenolide II Chemical compound C=C([C@@H]1C2)CCC[C@]1(C)C[C@H]1C2=C(C)C(=O)O1 OQYBLUDOOFOBPO-KCQAQPDRSA-N 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- SFKSOXSKEWXFFN-YKORFWMPSA-N C(C)C(O)[C@@]1(O)[C@@H](O)[C@H](O)[C@H](O1)CO.C(C)C(O)[C@@]1(O)[C@@H](O)[C@H](O)[C@H](O1)CO Chemical compound C(C)C(O)[C@@]1(O)[C@@H](O)[C@H](O)[C@H](O1)CO.C(C)C(O)[C@@]1(O)[C@@H](O)[C@H](O)[C@H](O1)CO SFKSOXSKEWXFFN-YKORFWMPSA-N 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- KVSNMTUIMXZPLU-UHFFFAOYSA-N D:A-friedo-oleanane Natural products CC12CCC3(C)C4CC(C)(C)CCC4(C)CCC3(C)C2CCC2(C)C1CCCC2C KVSNMTUIMXZPLU-UHFFFAOYSA-N 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- JUUHNUPNMCGYDT-UHFFFAOYSA-N Friedelin Natural products CC1CC2C(C)(CCC3(C)C4CC(C)(C)CCC4(C)CCC23C)C5CCC(=O)C(C)C15 JUUHNUPNMCGYDT-UHFFFAOYSA-N 0.000 description 1
- 208000012895 Gastric disease Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- PVKQULHHWVQXLE-UHFFFAOYSA-N Glycyrol Natural products C12=CC=C(O)C=C2OC2=C1C(=O)OC1=C2C(O)=C(CC=C(C)C)C(OC)=C1 PVKQULHHWVQXLE-UHFFFAOYSA-N 0.000 description 1
- MPDGHEJMBKOTSU-UHFFFAOYSA-N Glycyrrhetinsaeure Natural products C12C(=O)C=C3C4CC(C)(C(O)=O)CCC4(C)CCC3(C)C1(C)CCC1C2(C)CCC(O)C1(C)C MPDGHEJMBKOTSU-UHFFFAOYSA-N 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- QUQPHWDTPGMPEX-UHFFFAOYSA-N Hesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(COC4C(C(O)C(O)C(C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-UHFFFAOYSA-N 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- GFJNBLOMWYSKSS-UHFFFAOYSA-N Isoglycyrol Natural products COc1c2CCC(C)(C)Oc2cc3OC(=O)c4c(oc5c(O)cccc45)c13 GFJNBLOMWYSKSS-UHFFFAOYSA-N 0.000 description 1
- YNWXJFQOCHMPCK-UHFFFAOYSA-N Isoliquiritin Natural products OC1C(O)C(O)C(CO)OC1OC(C=C1)=CC=C1C=CC(=O)C1=CC=C(O)C=C1O YNWXJFQOCHMPCK-UHFFFAOYSA-N 0.000 description 1
- 241000497005 Ixophorus unisetus Species 0.000 description 1
- VTAJIXDZFCRWBR-UHFFFAOYSA-N Licoricesaponin B2 Natural products C1C(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2)C(O)=O)C)(C)CC2)(C)C2C(C)(C)CC1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O VTAJIXDZFCRWBR-UHFFFAOYSA-N 0.000 description 1
- MVAUGMLUJKTORM-UHFFFAOYSA-N Licoricidin Natural products COc1cc2OCC(Cc2cc1CC=C(C)C)c3ccc(O)c(CC=C(C)C)c3O MVAUGMLUJKTORM-UHFFFAOYSA-N 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 241001529936 Murinae Species 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- XQWFHGOIUZFQPJ-USTPAGJBSA-N Neoisoliquiritigenin Natural products O=C(/C=C/c1ccc(O)cc1)c1c(O)cc(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O2)cc1 XQWFHGOIUZFQPJ-USTPAGJBSA-N 0.000 description 1
- XQWFHGOIUZFQPJ-LXGDFETPSA-N Neoisoliquiritin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C=C1O)=CC=C1C(=O)\C=C\C1=CC=C(O)C=C1 XQWFHGOIUZFQPJ-LXGDFETPSA-N 0.000 description 1
- XQWFHGOIUZFQPJ-UHFFFAOYSA-N Neoisoliquiritin Natural products OC1C(O)C(O)C(CO)OC1OC(C=C1O)=CC=C1C(=O)C=CC1=CC=C(O)C=C1 XQWFHGOIUZFQPJ-UHFFFAOYSA-N 0.000 description 1
- JVAZJLFFSJARQM-UHFFFAOYSA-N O-n-hexyl beta-D-glucopyranoside Natural products CCCCCCOC1OC(CO)C(O)C(O)C1O JVAZJLFFSJARQM-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 208000006268 Sarcoma 180 Diseases 0.000 description 1
- YSKVBPGQYRAUQO-UZSYLJJSSA-N Schottenol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@H](C)CC[C@@H](CC)C(C)C)CC[C@H]33)C)C3=CC[C@H]21 YSKVBPGQYRAUQO-UZSYLJJSSA-N 0.000 description 1
- YSKVBPGQYRAUQO-UHFFFAOYSA-N Schottenol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CCC21 YSKVBPGQYRAUQO-UHFFFAOYSA-N 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 241000219315 Spinacia Species 0.000 description 1
- 235000009337 Spinacia oleracea Nutrition 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000893966 Trichophyton verrucosum Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 235000009392 Vitis Nutrition 0.000 description 1
- 241000219095 Vitis Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 102000004139 alpha-Amylases Human genes 0.000 description 1
- JZVFJDZBLUFKCA-FXIAWGAOSA-N alpha-Spinasterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)CC[C@H]33)C)C3=CC[C@H]21 JZVFJDZBLUFKCA-FXIAWGAOSA-N 0.000 description 1
- 229940024171 alpha-amylase Drugs 0.000 description 1
- JZVFJDZBLUFKCA-UTQQLQBSSA-N alpha-spinasterol Natural products CC[C@H](C=C[C@H](C)[C@H]1CC[C@H]2C3=CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C JZVFJDZBLUFKCA-UTQQLQBSSA-N 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000000507 anthelmentic effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- OQYBLUDOOFOBPO-YDHLFZDLSA-N atractylenolide II Natural products CC1=C2C[C@H]3C(=C)CCC[C@@]3(C)C[C@@H]2OC1=O OQYBLUDOOFOBPO-YDHLFZDLSA-N 0.000 description 1
- OAXKIRPCKWQWOQ-UHFFFAOYSA-N atractylenolide III Natural products CC1=C2CC3C(CCCC3=C)CC2(O)OC1=O OAXKIRPCKWQWOQ-UHFFFAOYSA-N 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- QUQPHWDTPGMPEX-UTWYECKDSA-N aurantiamarin Natural products COc1ccc(cc1O)[C@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1 QUQPHWDTPGMPEX-UTWYECKDSA-N 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 230000003177 cardiotonic effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- APSNPMVGBGZYAJ-GLOOOPAXSA-N clematine Natural products COc1cc(ccc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 APSNPMVGBGZYAJ-GLOOOPAXSA-N 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- MDZKJHQSJHYOHJ-UHFFFAOYSA-N crataegolic acid Natural products C1C(O)C(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MDZKJHQSJHYOHJ-UHFFFAOYSA-N 0.000 description 1
- YSKVBPGQYRAUQO-UBCZCFGNSA-N delta7 Stigmastenol Natural products O[C@@H]1C[C@@H]2[C@@](C)([C@@H]3C([C@H]4[C@@](C)([C@@H]([C@@H](CC[C@H](C(C)C)CC)C)CC4)CC3)=CC2)CC1 YSKVBPGQYRAUQO-UBCZCFGNSA-N 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 229960003720 enoxolone Drugs 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- OFMXGFHWLZPCFL-SVRPQWSVSA-N friedelin Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3CCC(=O)[C@@H]1C OFMXGFHWLZPCFL-SVRPQWSVSA-N 0.000 description 1
- MFVJCHSUSSRHRH-UHFFFAOYSA-N friedeline Natural products CC1(C)CCC2(C)CCC3C4(C)CCC5C(C)(C)C(=O)CCC5(C)C4CCC3(C)C2C1 MFVJCHSUSSRHRH-UHFFFAOYSA-N 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 210000004211 gastric acid Anatomy 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- LWESBHWAOZORCQ-UHFFFAOYSA-N glycyrol Chemical compound C12=CC=C(O)C=C2OC2=C1C(=O)OC1=C2C(OC)=C(CC=C(C)C)C(O)=C1 LWESBHWAOZORCQ-UHFFFAOYSA-N 0.000 description 1
- 239000001685 glycyrrhizic acid Substances 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 208000024798 heartburn Diseases 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 229940025878 hesperidin Drugs 0.000 description 1
- VUYDGVRIQRPHFX-UHFFFAOYSA-N hesperidin Natural products COc1cc(ccc1O)C2CC(=O)c3c(O)cc(OC4OC(COC5OC(O)C(O)C(O)C5O)C(O)C(O)C4O)cc3O2 VUYDGVRIQRPHFX-UHFFFAOYSA-N 0.000 description 1
- QUQPHWDTPGMPEX-QJBIFVCTSA-N hesperidin Chemical compound C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]4[C@@H]([C@H](O)[C@@H](O)[C@H](C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-QJBIFVCTSA-N 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- CFWLRXJPRRCJTI-UHFFFAOYSA-N iso-glycyrol Chemical compound C12=CC=C(O)C=C2OC2=C1C(=O)OC1=C2C(OC)=C(CCC(C)(C)O2)C2=C1 CFWLRXJPRRCJTI-UHFFFAOYSA-N 0.000 description 1
- YNWXJFQOCHMPCK-LXGDFETPSA-N isoliquiritin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C=C1)=CC=C1\C=C\C(=O)C1=CC=C(O)C=C1O YNWXJFQOCHMPCK-LXGDFETPSA-N 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- GBRZTUJCDFSIHM-UHFFFAOYSA-N licorisoflavan B Natural products C1C=2C(OC)=C(CC=C(C)C)C(O)=CC=2OCC1C1=CC=C(O)C(CC=C(C)C)=C1O GBRZTUJCDFSIHM-UHFFFAOYSA-N 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- MDZKJHQSJHYOHJ-LLICELPBSA-N maslinic acid Chemical compound C1[C@@H](O)[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MDZKJHQSJHYOHJ-LLICELPBSA-N 0.000 description 1
- 239000010271 massa medicata fermentata Substances 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- JVAZJLFFSJARQM-YBXAARCKSA-N n-Hexyl-beta-D-glucopyranoside Natural products CCCCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O JVAZJLFFSJARQM-YBXAARCKSA-N 0.000 description 1
- 229940105623 neo-synephrine Drugs 0.000 description 1
- ARGKVCXINMKCAZ-UHFFFAOYSA-N neohesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(CO)O3)OC3C(C(O)C(O)C(C)O3)O)=CC(O)=C2C(=O)C1 ARGKVCXINMKCAZ-UHFFFAOYSA-N 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 description 1
- 229950007908 piconol Drugs 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 239000010243 sho-seiryu-to Substances 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 230000002048 spasmolytic effect Effects 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- WNIFXKPDILJURQ-UHFFFAOYSA-N stearyl glycyrrhizinate Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C)CCC(C(=O)OCCCCCCCCCCCCCCCCCC)(C)CC5C4=CC(=O)C3C21C WNIFXKPDILJURQ-UHFFFAOYSA-N 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 208000018556 stomach disease Diseases 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- COBXDAOIDYGHGK-UHFFFAOYSA-N syringaldehyde Natural products COC1=CC=C(C=O)C(OC)=C1O COBXDAOIDYGHGK-UHFFFAOYSA-N 0.000 description 1
- YIBXWXOYFGZLRU-UHFFFAOYSA-N syringic aldehyde Natural products CC12CCC(C3(CCC(=O)C(C)(C)C3CC=3)C)C=3C1(C)CCC2C1COC(C)(C)C(O)C(O)C1 YIBXWXOYFGZLRU-UHFFFAOYSA-N 0.000 description 1
- ABKPQICIFGNRAA-MLUXTLINSA-N tangshenoside I Natural products COc1cc(C=CCOC(=O)C[C@](C)(CC(=O)O)O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)cc(OC)c1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O ABKPQICIFGNRAA-MLUXTLINSA-N 0.000 description 1
- GGGUGZHBAOMSFJ-GADYQYKKSA-N taraxerol Chemical compound CC([C@@H]1CC2)(C)[C@@H](O)CC[C@]1(C)[C@@H]1[C@]2(C)C2=CC[C@@]3(C)CCC(C)(C)C[C@H]3[C@]2(C)CC1 GGGUGZHBAOMSFJ-GADYQYKKSA-N 0.000 description 1
- HYTFUKZLSYXRDX-UHFFFAOYSA-N taraxerol Natural products CC1CCCC2C3(C)CCC4(C)C5CC(C)(C)CCC5(C)C=CC4(C)C3C(O)CC12C HYTFUKZLSYXRDX-UHFFFAOYSA-N 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- ORHBXUUXSCNDEV-UHFFFAOYSA-N umbelliferone Chemical compound C1=CC(=O)OC2=CC(O)=CC=C21 ORHBXUUXSCNDEV-UHFFFAOYSA-N 0.000 description 1
- HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
- 210000001113 umbilicus Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine preparation treating atrophic gastritis, the raw medicinal material of employing respectively: Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20 parts, Flos Inulae 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts.Imitate complementation with the raw medicinal material property of medicine selected by top, evaded the choosing of the mutual inhibition of compatibility, mutual restraint between two drugs, the mutual-detoxication between medicine, make medicine mutual reinforcement between, make effect notable mutually, there is raising immunity.Treatment can reach the purpose of warming middle-JIAO and strengthening the spleen, dispersing the stagnated live-QI to relieve the stagnation of QI, anti-inflammatory analgetic.For oral administration to atrophic gastritis, insufficiency of the spleen, asthenia there is definite curative effect.
Description
Technical field
The present invention relates to a kind of field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation treating atrophic gastritis, there is warming middle-JIAO
Spleen invigorating, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of anti-inflammatory analgetic, for atrophic gastritis, insufficiency of the spleen, asthenia effect is obvious.
Background technology
Atrophic gastritis is also referred to as chronic atrophic gastritis, and with gastric epithelial and body of gland atrophy, number reduces, and gastric mucosa becomes
Thin, mucosa basic unit thickens, or companion's gland metaplasia and intestinal gland metaplasia, or has the chronic digestible system disease that atypical hyperplasia is characterized
Sick.Often show as epigastrium dull pain, distension, belch, inappetence, or become thin, anemia etc., without specificity.Atrophic gastritis
Clinical manifestation not only lacks specificity, and with lesion degree not quite identical.Following clinical manifestation often occurs: gastral cavilty portion is swollen
Full；Gastral cavilty portion pain；Heartburn and indigestion symptom；Stool abnormity and weakness symptom；Anemia.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation treating atrophic gastritis, there is warming middle-JIAO and strengthening the spleen, soothing the liver solution
Strongly fragrant, effect of anti-inflammatory analgetic, for atrophic gastritis, insufficiency of the spleen, asthenia effect is obvious.
The technical solution used in the present invention is:
The Chinese medicine preparation of described treatment atrophic gastritis, the raw medicinal material of employing respectively: Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts,
Radix Glycyrrhizae Preparata 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20
Part, Flos Inulae 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts.
Its preparation method is for following steps: step one), weighting raw materials material Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10
Part, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20 parts, Flos Inulae
Spend 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts, go the removal of impurity, eluriate rapidly with cold boiled water water, drip
Anhydrate liquid, dries；
Step 2), step one) obtained raw medicinal material is respectively prepared decoction pieces, puts in suitable decocting device, add clear water and fit
Amount, soaks suitable time, is heated to boiling, keeps slight boiling condition certain time (about 0.5～1 hour), separates fried liquid；
Step 3), step 2) obtained the medicinal residues after filtering and added water appropriate decoction, after regulation decoction 2～3 times,
Merge fried liquid, filter or settlement separate fried liquid；
Step 4), step 3) obtained Chinese medicine preparation packs, it is thus achieved that commodity Chinese medicine preparation.
In the raw medicinal material that the present invention chooses, its effect and pharmacological action respectively:
Radix Codonopsis: there is invigorating the spleen and replenishing QI, effect of strengthening spleen and tonifying lung.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency
Cough, interior-heat is quenched one's thirst.Meridian distribution of property and flavor: property is put down, sweet in the mouth, micro-acid.Return spleen, lung meridian.Chemical composition: Radix Codonopsis contains triterpenoid compound
Freidelin (friedelin), alnulin acetas, bessisterol and glycoside thereof, Δ 7-stigmastenol and Fructus Vitis viniferae thereof
Glucoside, spinach sterone (spinesterone).Another (atractylenolide III) Han atractylenoide Ⅲ, atractyloide II
(atractylenolide II), syringic aldehyde (syringaldehyde), Syringin (syringin), vanillic acid (vanillic
Acid), 5-hydroxyl-2-piconol (5-hydroxy-2-pyridinemethanol), α-furyl carboxylic acid (α-
Furancarboxylic acid), n-hexyl-glycoside (n-hexyl-β-D-glucopyranoside), ethyl-α-D-
Fructofuranoside (ethyl-α-D-fructofuranoside), and nicotinic acid, 4 kinds of heteropolysaccharide and monosaccharide etc..Still containing tangshenoside
I, codonolactone and codopiloic acid.
Poria: property slightly sweet flavor is put down, and enters the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Energy
Enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.Dysuria, edema distension, expectorant can be controlled
Drink cough with dyspnea, vomiting, malignant histocytosis, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.
Pericarpium Citri Reticulatae: Pericarpium Citri Reticulatae contains hesperidin about 8.4%, Nobiletin (nobiletin) about 0.15%. separately contain Neosynephrine (to hydroxyl
Forint) 0.28%-2.54%.[nature and flavor] are bitter, pungent, temperature.[return through] returns lung, spleen channel.
[attending effectiveness]: regulating qi-flowing for strengthening spleen, in tune, dampness, reduce phlegm.Cure mainly distension and fullness in the abdomen or pain, the digestion of stagnation of QI in spleen and stomach
Bad.Abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool.Phlegm-damp stops up the cough and asthma of lung.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough
Cough abundant expectoration.
The Rhizoma Pinelliae: the pungent scattered warm-dryness syndrome of these product is poisonous, main enter taste double enter lung, water of manageing it is wet, lowering the adverse flow of QI, and kind taste damp-phlegm of dispelling.
Water is wet to be gone, spleen is strong and sputum from disappearing, inverse gas drops then harmonization of the stomach and feeling of fullness vomiting from only, therefore is drying dampness to eliminate phlegm, and stopping nausea and vomiting by lowering the adverse flow of QI, disappear painful abdominal mass
The good medicine of eliminating stagnation.Both cure mainly the abundant expectoration cough with asthma QI rising in reverse order of spleen damp-phlegm heap soil or fertilizer over and around the roots, such as ERCHEN TANG, XIAOQINGLONG TANG, control again the dizziness of criminal on damp-phlegm
The diseases such as palpitation and insomnia, such as banxia baizhu tianma decoction, also can control wind-phlegm and tell inverse, headache limb fiber crops, hemiplegia, facial hemiparalysis, such as jade
Kettle ball.
Fructus Amomi: nature and flavor: acrid in the mouth, warm in nature.Gui Jing: return spleen channel, stomach warp, kidney channel.Function: removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy
Antiabortive.Cure mainly: for turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is the most hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Cortex Magnoliae Officinalis: nature and flavor: bitter；Pungent；Warm in nature.Gui Jing: spleen channel；Stomach warp；Large intestine channel.Function: circulation of qi promoting removing food stagnancy；Dampness is except full；Fall
Against relievining asthma.Cure mainly: stagnation of QI due to dyspepsia；Abdominal distention constipation；Retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea；Expectorant stops up QI rising in reverse order；Fullness in the chest is breathed with cough.
The Radix Linderae: effect: 1, the excitation of volatile oil: time for oral administration, have excited corticocerebral effect, and have promotion
Breathe, excited cardiac muscle, accelerate blood circulation, raising blood pressure and the effect of diaphoresis.Local topical makes local vascular dilation, blood circulation add
Speed, relaxes muscle spasm pain.2, bacteriostasis: to staphylococcus aureus, α-hemolytic streptococcus, Bacillus typhi,
Bacillus proteus, bacillus pyocyaneus, escherichia coli all have inhibitory action.3, on gastral impact: have the report Radix Linderae to gastrointestinal smooth
Flesh has dual function, additionally, the Radix Linderae can increase the secretion of Digestive system.4, anastalsis: experiment in vitro proves, Radix Linderae dry powder can be bright
The aobvious plasma in rabbit recalcification time that shortens, promotion blood clotting and good anastalsis.5, other effect: feed big with the Radix Linderae for a long time
Mus, can make body weight increase, and murine sarcoma-180 is had inhibitory action.Its Borneolum Syntheticum can diaphoresis, excitement, spasmolytic, anthelmintic etc..
Flos Caryophylli: have warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Warming middle-JIAO to send down the adverse QI；The function of warming the kidney to activate YANG.Cure mainly: control singultus, vomiting, regurgitation,
Dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm.
Rhizoma Zingiberis: [nature and flavor, return through] acrid in the mouth, property heat.Return spleen, stomach, the heart, lung meridian.[effect] warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dry
Wet expectorant, warming the lung to resolve fluid-retention.[curing mainly] coldness and pain in the epigastrium；Vomiting；Having loose bowels, YANG-depletion is fainted inverse；Cold fluid-retention is breathed with cough；Arthralgia due to cold-dampnes.
Fructus Crataegi: slightly warm in nature, sour in the mouth is sweet, enters spleen, stomach, Liver Channel, has promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, the function of convergence dysentery relieving.Right
Meat amasss phlegm retention, feeling of fullness acid regurgitation, dysentery hemorrhoidal hamorrhage, lumbago hernia, after-pains in puerperal, lochiorrhea, the food stagnation of children's's breast etc., all has treatment
Effect.Fructus Crataegi energy prevention and cure of cardiovascular disease, has expansion blood vessel, heart tonifying, increase coronary flow, improves in heart vigor, excitement
Pivot nervous system, reduce blood pressure and cholesterol, vessel softening and diuresis and sedation；Prevent and treat arteriosclerosis, anti-aging, anticancer
Effect.Crataegolic acid also has cardiotonic, also benefits senile heart disease.Appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis,
Reduce phlegm circulation of qi promoting.For meat stagnant long-pending, lump in the abdomen, abdominal distention feeling of fullness, stasis blocking stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc..
Massa Medicata Fermentata: nature and flavor: sweet, acrid, warm.Gui Jing: return spleen, stomach warp.Effect: invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation.Cure mainly: be used for drinking
Food is stagnated, dyspepsia, distension and fullness in the abdomen, inappetence, vomiting dysentery.
Fructus Hordei Germinatus: circulation of qi promoting helps digestion, spleen benefiting and stimulating the appetite, moves back breast relieving distension.Not disappearing for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, breast antiperspirant is strongly fragrant
Long-pending, distending pain of the breast, women weans, Fructus Hordei Germinatus invigorating the spleen and regulating the stomach lactogenesis.For insufficiency of the spleen lack of appetite, breast antiperspirant smoulders.Fructus Hordei Germinatus (parched) circulation of qi promoting helps digestion
Galactopoiesis.Not disappearing for food stagnation, women weans.Fructus Hordei Germinatus (parched to brown) relieving dyspepsia.Do not disappear for food stagnation, abdominal distention.Main warming the middle warmer and descending qi, opens
Stomach spleen invigorating, expedites the emergence of lower tire, changes dyspepsia, and de-swelling is full, and emesis is inverse, broken note of the ancient Chinese, expectorant painful abdominal mass.Digestion-aid effect: this product contains α and beta amylase.
And starch is the mixture of amylose and amylopectin.The glucose molecule of composition amylose is connected with α-Isosorbide-5-Nitrae glycoside key, and in straight chain
Arrangement.Amylopectin is by several short straight chain polyglucose cross arrangements.Branched amylopectin molecules also has in addition to α-Isosorbide-5-Nitrae glycoside key
α-1,6 glycoside keys.α and beta amylase hydrolyzable α-Isosorbide-5-Nitrae glycoside key, to α-1,6 glycoside keys are without effect.Beta amylase can be by complete for amylose water
Solution becomes maltose, and alpha amylase is then allowed to resolve into short straight key polyglucose (i.e. dextrin), and the latter can hydrolyze for beta amylase again
Become maltose.Therefore starch is decomposed into maltose and dextrin under the effect of α and beta amylase.Fructus Hordei Germinatus decoct is to gastric acid and stomach
The secretion of protease seemingly has slight facilitation.
Radix Glycyrrhizae: property is put down, sweet in the mouth.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion poison
Property, strong.Chemical composition: Radix Glycyrrhizae contains multiple chemical composition, main component has glycyrrhizic acid, liquiritin etc..Separate from Radix Glycyrrhizae
The compound gone out has glycyrrhizin, enoxolone, liquiritin, isoliquiritin, neoliquriitin, neoisoliquiritin, glycyrrhizin, different sweet
The tens of kinds of compounds such as grass element and licoricidin (+)-Licoricidin., glycyrol, isoglycyrol, 7-methylcoumarin essence, umbelliferone.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.[function with cure mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.For pacifying
Nerve, the headache of positive wind syndrome of head, lump in the abdomen stomachache, breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia.
With selected by top the raw medicinal material property of medicine imitate complementation, evaded the mutual inhibition of compatibility between medicine, mutual restraint between two drugs, the mutual-detoxication it
Choosing, makes medicine mutual reinforcement between, makes effect notable mutually, have raising immunity.Treatment can reach warming middle-JIAO and strengthening the spleen, soothing the liver solution
Strongly fragrant, the purpose of anti-inflammatory analgetic.For oral administration to atrophic gastritis, insufficiency of the spleen, asthenia there is definite curative effect.Effect of Chinese medicine preparation of the present invention
Confirmed in the middle of clinical practice, clinical test of pesticide effectiveness material and model case:
1. an XX, man, 43 years old.Stomach dull pain, time light time weight more than 5 years, once took multiple Chinese medicine and western medicine, do not healed always, nearly 1
Within individual month, increase the weight of.Just examining: stomachache is indistinct, dryness of the mouth and throat is not drunk, and appetite decrescence, is made swollen after food, eats pungent product pain the most very, head
Dizzy weak, two dryness and uneasy feeling of the eye, blurring of vision, dysphoria with feverish sensation in the chest palms and soles, shallow complexion, red and uncoated tongue, thready and rapid pulse.Gastropathy with the passing of time, hindered by stomach-Yin,
Losing in moistening foster, the stagnation of QI is had a pain.Control with warming middle-JIAO and strengthening the spleen, dispersing the stagnated live-QI to relieve the stagnation of QI, anti-inflammatory analgetic method.After clothes we 10 doses, stomachache stops, all diseases
Know and subtract, only dry stool, feverish sensation in the palms and soles.After continuing to take we 25 doses, transference cure, recover.
Method and effective dose: Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15
Part, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20 parts, Flos Inulae 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, celestial being
Crane grass 15 parts, Radix Notoginseng 15 parts.
Its preparation method is for following steps: step one), weighting raw materials material Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10
Part, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20 parts, Flos Inulae
Spend 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts, go the removal of impurity, eluriate rapidly with cold boiled water water, drip
Anhydrate liquid, dries；
Step 2), step one) obtained raw medicinal material is respectively prepared decoction pieces, puts in suitable decocting device, add clear water and fit
Amount, soaks suitable time, is heated to boiling, keeps slight boiling condition certain time (about 0.5～1 hour), separates fried liquid；
Step 3), step 2) obtained the medicinal residues after filtering and added water appropriate decoction, after regulation decoction 2～3 times,
Merge fried liquid, filter or settlement separate fried liquid；
Step 4), step 3) obtained Chinese medicine preparation packs, it is thus achieved that commodity Chinese medicine preparation.
Decoction oral is main, every day 1 dose, is decocted in water for oral dose, and sooner or later respectively takes 1 time, each 100ml decoction being taken warmly.
Detailed description of the invention
The Chinese medicine preparation of described treatment atrophic gastritis, the raw medicinal material of employing respectively: Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts,
Radix Glycyrrhizae Preparata 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20
Part, Flos Inulae 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts.
Its preparation method is for following steps: step one), weighting raw materials material Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10
Part, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20 parts, Flos Inulae
Spend 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts, go the removal of impurity, eluriate rapidly with cold boiled water water, drip
Anhydrate liquid, dries；
Step 2), step one) obtained raw medicinal material is respectively prepared decoction pieces, puts in suitable decocting device, add clear water and fit
Amount, soaks suitable time, is heated to boiling, keeps slight boiling condition certain time (about 0.5～1 hour), separates fried liquid；
Step 3), step 2) obtained the medicinal residues after filtering and added water appropriate decoction, after regulation decoction 2～3 times,
Merge fried liquid, filter or settlement separate fried liquid；
Step 4), step 3) obtained Chinese medicine preparation packs, it is thus achieved that commodity Chinese medicine preparation.
Claims (2)
1. the Chinese medicine preparation of a described treatment atrophic gastritis, it is characterised in that the raw medicinal material of employing respectively: Radix Bupleuri 15
Part, the Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Platycodonis 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis
15 parts of rope, Pericarpium Citri Reticulatae 20 parts, Flos Inulae 15 parts, Fructus Mume 10 parts, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts.
The Chinese medicine preparation for the treatment of atrophic gastritis the most according to claim 1, it is characterised in that: its preparation method, preparation
Method is for following steps: step one), weighting raw materials material Radix Bupleuri 15 parts, the Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Fructus Citri tangerinae
Obstruct 15 parts, Radix Cynanchi Paniculati 15 parts, Fructus Forsythiae 15 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae 20 parts, Flos Inulae 15 parts, Fructus Mume 10
Part, Fructus Trichosanthis 15 parts, Herba Agrimoniae 15 parts, Radix Notoginseng 15 parts, go the removal of impurity, eluriate rapidly with cold boiled water water, drain water liquid, dry；
Step 2), step one) obtained raw medicinal material is respectively prepared decoction pieces, puts in suitable decocting device, it is appropriate to add clear water, leaching
Bubble suitable time, is heated to boiling, keeps slight boiling condition certain time (about 0.5～1 hour), separates fried liquid；
Step 3), step 2) obtained the medicinal residues after filtering and added water appropriate decoction, after decocting 2～3 times by regulation, merging
Fried liquid, filters or settlement separate fried liquid；
Step 4), step 3) obtained Chinese medicine preparation packs, it is thus achieved that commodity Chinese medicine preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610804176.1A CN106266106A (en) | 2016-08-26 | 2016-08-26 | The Chinese medicine preparation for the treatment of atrophic gastritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610804176.1A CN106266106A (en) | 2016-08-26 | 2016-08-26 | The Chinese medicine preparation for the treatment of atrophic gastritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106266106A true CN106266106A (en) | 2017-01-04 |
Family
ID=57710967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610804176.1A Pending CN106266106A (en) | 2016-08-26 | 2016-08-26 | The Chinese medicine preparation for the treatment of atrophic gastritis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106266106A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106581239A (en) * | 2017-01-22 | 2017-04-26 | 吴冬梅 | Traditional Chinese medicine preparation for treatment of atrophic gastritis |
| CN106619937A (en) * | 2017-01-22 | 2017-05-10 | 侯春华 | Anti-inflammatory soup with functions of harmonizing stomach and relieving pain |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412308A (en) * | 2015-12-21 | 2016-03-23 | 荥阳市藤本保健品有限公司 | Traditional Chinese medicinal preparation for treating atrophic gastritis |
-
2016
- 2016-08-26 CN CN201610804176.1A patent/CN106266106A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412308A (en) * | 2015-12-21 | 2016-03-23 | 荥阳市藤本保健品有限公司 | Traditional Chinese medicinal preparation for treating atrophic gastritis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106581239A (en) * | 2017-01-22 | 2017-04-26 | 吴冬梅 | Traditional Chinese medicine preparation for treatment of atrophic gastritis |
| CN106619937A (en) * | 2017-01-22 | 2017-05-10 | 侯春华 | Anti-inflammatory soup with functions of harmonizing stomach and relieving pain |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102068707B (en) | Traditional Chinese medicine contrast medium adjuvant used for B ultrasonic and preparation method thereof | |
| CN101537156A (en) | Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease | |
| CN105412308A (en) | Traditional Chinese medicinal preparation for treating atrophic gastritis | |
| CN104971215A (en) | Traditional Chinese medicine composition for treating spleen-deficiency gastrasthenia type chronic gastritis and preparation method thereof | |
| CN105412307A (en) | Stomach-harmonizing pain-relieving inflammation-diminishing soup | |
| CN105106885A (en) | Decoction capable of calming adverse-rising energy, relieving pain and nourishing stomach | |
| CN106266106A (en) | The Chinese medicine preparation for the treatment of atrophic gastritis | |
| CN104288745A (en) | Traditional Chinese medicine for treating CG (Chronic Gastritis) | |
| CN103479947B (en) | The preparation method of control constipation medicine | |
| CN104547313B (en) | It is a kind of to treat lung cancer, breast cancer, the medicine of lymph cancer and preparation method | |
| CN105816753A (en) | Preparation for eliminating phlegm and relieving cough | |
| CN102895392B (en) | Chinese medicine for treating duodenal ulcer | |
| CN105749172A (en) | Medicament for treating gastric calculus and preparation thereof | |
| CN104436098A (en) | Traditional Chinese medicine preparation for treating multiple intestinal polyps | |
| CN104383403A (en) | Traditional Chinese medicinal composition for treating chronic gastritis | |
| CN103479948B (en) | The anti-medicine treated constipation | |
| CN107854662A (en) | A kind of Chinese medicine preparation for treating cirrhotic ascites and preparation method thereof | |
| CN106581239A (en) | Traditional Chinese medicine preparation for treatment of atrophic gastritis | |
| CN102335314B (en) | Chinese medicinal composition for treating stomach diseases | |
| CN106729570A (en) | Clearing damp removes hot anti-inflammatory soup | |
| CN106266914A (en) | The kidney warming stopping nausea and vomiting by lowering the adverse flow of QI soup | |
| CN104383488A (en) | Traditional Chinese medicine preparation for treating chronic gastritis | |
| CN105363013A (en) | Soup capable of dispelling dampness, removing heat and diminishing inflammation | |
| CN105853882A (en) | Medicine for treating stomach illness and preparation method | |
| CN106310184A (en) | Damp-clearing heat-removing anti-inflammatory soup |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170104 |