CN106265560B - A kind of Sobering-up buccal tablet and preparation method thereof - Google Patents
A kind of Sobering-up buccal tablet and preparation method thereof Download PDFInfo
- Publication number
- CN106265560B CN106265560B CN201610583446.0A CN201610583446A CN106265560B CN 106265560 B CN106265560 B CN 106265560B CN 201610583446 A CN201610583446 A CN 201610583446A CN 106265560 B CN106265560 B CN 106265560B
- Authority
- CN
- China
- Prior art keywords
- parts
- sobering
- buccal tablet
- powder
- raw material
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000006189 buccal tablet Substances 0.000 title claims abstract description 49
- 229940046011 buccal tablet Drugs 0.000 title claims abstract description 47
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 241000196324 Embryophyta Species 0.000 claims abstract description 81
- 150000004676 glycans Chemical class 0.000 claims abstract description 51
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 51
- 239000005017 polysaccharide Substances 0.000 claims abstract description 51
- 239000000284 extract Substances 0.000 claims abstract description 48
- 239000000843 powder Substances 0.000 claims abstract description 46
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 44
- 239000000203 mixture Substances 0.000 claims abstract description 31
- 239000000126 substance Substances 0.000 claims abstract description 31
- 238000000605 extraction Methods 0.000 claims abstract description 30
- 239000002994 raw material Substances 0.000 claims abstract description 30
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 25
- 235000012907 honey Nutrition 0.000 claims abstract description 25
- 239000000741 silica gel Substances 0.000 claims abstract description 25
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 25
- 235000013351 cheese Nutrition 0.000 claims abstract description 24
- 239000000853 adhesive Substances 0.000 claims abstract description 20
- 230000001070 adhesive effect Effects 0.000 claims abstract description 20
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 13
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 13
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 13
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 13
- 241001248610 Ophiocordyceps sinensis Species 0.000 claims abstract description 13
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 13
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 13
- 235000008434 ginseng Nutrition 0.000 claims abstract description 13
- 241000234435 Lilium Species 0.000 claims abstract description 11
- 238000002156 mixing Methods 0.000 claims description 23
- 230000001954 sterilising effect Effects 0.000 claims description 20
- 238000004659 sterilization and disinfection Methods 0.000 claims description 20
- 239000006228 supernatant Substances 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 14
- 241000208340 Araliaceae Species 0.000 claims description 12
- 239000011812 mixed powder Substances 0.000 claims description 12
- 239000013049 sediment Substances 0.000 claims description 12
- 229920002774 Maltodextrin Polymers 0.000 claims description 11
- 239000005913 Maltodextrin Substances 0.000 claims description 11
- 229940035034 maltodextrin Drugs 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000005516 engineering process Methods 0.000 claims description 9
- 238000007796 conventional method Methods 0.000 claims description 8
- 239000012153 distilled water Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 206010013786 Dry skin Diseases 0.000 claims description 6
- 238000007908 dry granulation Methods 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 238000000874 microwave-assisted extraction Methods 0.000 claims description 3
- 238000012545 processing Methods 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 238000004821 distillation Methods 0.000 claims 1
- 210000004185 liver Anatomy 0.000 abstract description 21
- 230000000694 effects Effects 0.000 abstract description 13
- 230000006378 damage Effects 0.000 abstract description 11
- 230000035622 drinking Effects 0.000 abstract description 5
- 230000008520 organization Effects 0.000 abstract description 5
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 description 26
- 241000700159 Rattus Species 0.000 description 18
- 238000003304 gavage Methods 0.000 description 7
- 238000003305 oral gavage Methods 0.000 description 7
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 description 6
- 230000037396 body weight Effects 0.000 description 6
- 235000020097 white wine Nutrition 0.000 description 6
- 230000004048 modification Effects 0.000 description 5
- 238000012986 modification Methods 0.000 description 5
- 230000009467 reduction Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- 238000001556 precipitation Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 239000011149 active material Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 210000002311 liver mitochondria Anatomy 0.000 description 2
- 239000007937 lozenge Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- 208000007848 Alcoholism Diseases 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 206010016825 Flushing Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000010224 hepatic metabolism Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 201000007270 liver cancer Diseases 0.000 description 1
- 210000005229 liver cell Anatomy 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid group Chemical class S(O)(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610583446.0A CN106265560B (en) | 2016-07-17 | 2016-07-17 | A kind of Sobering-up buccal tablet and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610583446.0A CN106265560B (en) | 2016-07-17 | 2016-07-17 | A kind of Sobering-up buccal tablet and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106265560A CN106265560A (en) | 2017-01-04 |
CN106265560B true CN106265560B (en) | 2018-11-09 |
Family
ID=57652178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610583446.0A Active CN106265560B (en) | 2016-07-17 | 2016-07-17 | A kind of Sobering-up buccal tablet and preparation method thereof |
Country Status (1)
Country | Link |
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CN (1) | CN106265560B (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102266367A (en) * | 2011-07-19 | 2011-12-07 | 三峡大学 | Medicinal composition for treating alcoholic liver injury |
CN102715390A (en) * | 2012-05-03 | 2012-10-10 | 湖北炎帝农业科技股份有限公司 | Liver-protecting functional food and preparation method thereof |
CN104739896A (en) * | 2015-03-06 | 2015-07-01 | 吉林省现代中药工程研究中心有限公司 | Composite fungal intercellular polysaccharide composition with liver protecting function and preparation method |
CN105747203A (en) * | 2016-02-22 | 2016-07-13 | 郑州师范学院 | Caulis dendrobii medlar cordyceps polysaccharide compound, and preparation method and application thereof |
-
2016
- 2016-07-17 CN CN201610583446.0A patent/CN106265560B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102266367A (en) * | 2011-07-19 | 2011-12-07 | 三峡大学 | Medicinal composition for treating alcoholic liver injury |
CN102715390A (en) * | 2012-05-03 | 2012-10-10 | 湖北炎帝农业科技股份有限公司 | Liver-protecting functional food and preparation method thereof |
CN104739896A (en) * | 2015-03-06 | 2015-07-01 | 吉林省现代中药工程研究中心有限公司 | Composite fungal intercellular polysaccharide composition with liver protecting function and preparation method |
CN105747203A (en) * | 2016-02-22 | 2016-07-13 | 郑州师范学院 | Caulis dendrobii medlar cordyceps polysaccharide compound, and preparation method and application thereof |
Also Published As
Publication number | Publication date |
---|---|
CN106265560A (en) | 2017-01-04 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20231007 Address after: Room 124, No. 779 Tanghekou Street, Tanghekou Town, Huairou District, Beijing, 101400 Patentee after: Beijing Chuyin Health Technology Co.,Ltd. Address before: 511466 room 817, No. 181, Haibin Road, Nansha District, Guangzhou City, Guangdong Province Patentee before: Guangdong Jiapeng Technology Co.,Ltd. Effective date of registration: 20231007 Address after: 511466 room 817, No. 181, Haibin Road, Nansha District, Guangzhou City, Guangdong Province Patentee after: Guangdong Jiapeng Technology Co.,Ltd. Address before: 453003 east section of Jinsui Avenue, Hongqi District, Xinxiang City, Henan Province Patentee before: XINXIANG MEDICAL University |
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TR01 | Transfer of patent right | ||
DD01 | Delivery of document by public notice |
Addressee: Liu Pengyu Document name: Notice of Qualified Procedures |
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DD01 | Delivery of document by public notice |