CN106264508B - Body weight, heart rhythm and body temperature monitoring device for mice - Google Patents
Body weight, heart rhythm and body temperature monitoring device for mice Download PDFInfo
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- CN106264508B CN106264508B CN201610672411.4A CN201610672411A CN106264508B CN 106264508 B CN106264508 B CN 106264508B CN 201610672411 A CN201610672411 A CN 201610672411A CN 106264508 B CN106264508 B CN 106264508B
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- connecting seat
- hemispherical cover
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- 241000699670 Mus sp. Species 0.000 title claims abstract description 47
- 230000033764 rhythmic process Effects 0.000 title claims abstract description 18
- 230000036760 body temperature Effects 0.000 title claims abstract description 15
- 238000012806 monitoring device Methods 0.000 title claims description 6
- 230000037396 body weight Effects 0.000 title claims description 5
- 238000002347 injection Methods 0.000 claims abstract description 82
- 239000007924 injection Substances 0.000 claims abstract description 82
- 241000699666 Mus <mouse, genus> Species 0.000 claims abstract description 26
- 238000010253 intravenous injection Methods 0.000 claims abstract description 14
- 238000012544 monitoring process Methods 0.000 claims abstract description 7
- 238000001125 extrusion Methods 0.000 claims description 19
- 238000005452 bending Methods 0.000 claims description 14
- 238000005303 weighing Methods 0.000 claims description 11
- 239000007921 spray Substances 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 238000005192 partition Methods 0.000 claims description 6
- 239000000523 sample Substances 0.000 claims description 6
- 238000002955 isolation Methods 0.000 claims description 5
- 230000009471 action Effects 0.000 claims description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims description 4
- 229920000742 Cotton Polymers 0.000 claims description 3
- 229910000831 Steel Inorganic materials 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims description 3
- 238000012790 confirmation Methods 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 3
- 230000037431 insertion Effects 0.000 claims description 3
- 239000010959 steel Substances 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000003814 drug Substances 0.000 description 11
- 229940079593 drug Drugs 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 4
- 238000001990 intravenous administration Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000009529 body temperature measurement Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 230000003139 buffering effect Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000003255 drug test Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01G—WEIGHING
- G01G19/00—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups
- G01G19/44—Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for weighing persons
Abstract
The invention relates to a device for monitoring the weight, heart rhythm and body temperature of a mice, which comprises a base and a transparent hemispherical cover body; the base comprises a round base body and a connecting seat connected with the side wall of the round base body, one side of the transparent hemispherical cover body is hinged on the round base body, and a hook-shaped opening is formed in the bottom of the other side of the transparent hemispherical cover body; the connecting part of the round seat body and the connecting seat is provided with a first groove, the connecting seat is provided with a second groove, and the first groove is connected with the second groove; the bottom of the connecting seat is internally provided with an injection needle driving component, and the tail part of the second groove is provided with a tail clamping body of the mouse; a limiting component is arranged at the joint of the round seat body and the connecting seat. The invention can place the mice in the round seat for intravenous injection, can monitor the weight, the heart rhythm, the body temperature and other information of the mice, not only can improve the intravenous injection quality, but also has extremely high efficiency.
Description
Technical Field
The invention relates to the technical field of auxiliary equipment for white mouse experiments, in particular to a device for monitoring the weight, the heart rhythm and the body temperature of a white mouse.
Background
In the prior art, a drug test is required to be carried out on mice in the medical technical field, so that the effect of the drug is determined. In a more frequent operation, the mice are observed after intravenous injection of the medicines, the mice are manually grabbed by the traditional injection mode, or the mice are grabbed by complex equipment and then are intravenous injected, and the mice are grabbed and placed in another container for observation after the intravenous injection, so that the mice are removed, and the workload is increased. In addition, the existing complicated device for injecting the mice (i.e. the device not used for manually injecting) is difficult to accurately inject the medicines during injection, and stable injection is difficult to perform, namely, slow injection is required during injection of some medicines, but the existing device cannot realize, so that when some violent medicines are injected, the mice die due to the fact that slow injection cannot be performed. In addition, how to acquire the sign information of the mice before and after injection is a very inequality problem of the mice experiments, the existing mode is to weigh the mice through a weighing device, press the mice through manually wearing gloves, and collect heart rate and body temperature of the mice by using corresponding instruments, so that the collected mode has errors in data and is troublesome to operate.
Disclosure of Invention
The invention aims to provide a device for monitoring the weight, the heart rhythm and the body temperature of a white mouse, which can effectively collect the weight, the heart rhythm and the body temperature data of the white mouse before and after the intravenous injection of the mouse.
The invention is realized in the following way: a white mouse weight, rhythm of heart, body temperature monitoring devices, its characterized in that: comprises a base and a transparent hemispherical cover body; the base comprises a round base body and a connecting seat connected with the side wall of the round base body, one side of the transparent hemispherical cover body is hinged on the round base body, and a hook-shaped opening is formed in the bottom of the other side of the transparent hemispherical cover body; so as to be beneficial to the tail of the mice to extend out of the hooked opening after the transparent hemispherical cover body is covered; four reset posts are arranged on the transparent hemispherical cover body in a penetrating way, and a limiting net is arranged at the end part of the reset post, which is positioned in the transparent hemispherical cover body, so that when the reset post is pressed down, the limiting net covers the mice and limits the actions of the mice; the end part of the reset column, which is positioned outside the transparent hemispherical cover body, is provided with a supporting plate; the arc top of the transparent hemispherical cover body is fixedly connected with a screw rod, the screw rod passes through the center of the supporting plate, and a limit screw is sleeved on the screw rod; the circular base body comprises a hollow chassis and a weighing disc arranged on the hollow chassis, and a weight sensor is arranged between the weighing disc and the hollow chassis; the middle part of the weighing disc is provided with a groove, an elastic gasket is arranged in the groove, and an annular pressure sensor for detecting the heart rhythm of the mice is also arranged in the elastic gasket; an infrared temperature measuring probe for detecting the body surface temperature of the mice is arranged in the middle of the annular pressure sensor; the elastic gasket comprises a gasket and a return spring arranged below the gasket; after the reset spring is compressed, the gasket can be pressed into the groove; the infrared temperature measuring probe is connected with the infrared temperature measuring module through a wire; a rechargeable battery is arranged in the hollow chassis, the rechargeable battery supplies power for a circuit board, an MCU is arranged on the circuit board, and the MCU is connected with the weight sensor, the annular pressure sensor and the infrared temperature measuring module; a first groove is formed in the joint of the circular base body and the connecting base, a second groove is formed in the connecting base, and the first groove is connected with the second groove; a partition plate is transversely arranged in the bottom of the connecting seat, and divides the inner side of the bottom of the connecting seat into an upper cavity and a lower cavity; the isolation plate is provided with a square opening; the bottom of the connecting seat is internally provided with an injection needle driving assembly, and the injection needle driving assembly comprises an asynchronous motor, a screw rod and an extrusion plate; the two ends of the screw rod are fixed in the lower cavity of the connecting seat, the asynchronous motor is arranged in the upper cavity, and a rotating shaft of the asynchronous motor penetrates through the square opening to be connected with one end of the screw rod; the asynchronous motor is connected with the MCU through an asynchronous driving circuit, the extrusion plate is longitudinally and vertically arranged and fixedly arranged on the screw rod, and the extrusion plate can move back and forth on the square opening; a rubber gasket is arranged on the front surface of the extrusion plate; a limiting plate and an injection needle cylinder are arranged in the upper cavity; the injection needle cylinder is positioned between the extrusion plate and the limiting plate, an injection head of the injection needle cylinder penetrates through the through hole, a channel is arranged between the upper cavity and the second groove, an injection needle is arranged on the injection head, and the injection needle comprises an injection buffer part, a bending part and an injection part in sequence; the injection buffer part, the bending part and the injection part are sequentially connected; an included angle formed between the injection buffer part and the bending part is 120-140 degrees; the included angle formed between the bending part and the injection part is 140-160 degrees; the injection part passes through the channel, and the injection part is exposed out of the surface of the first groove; the tail part of the second groove is provided with a tail clamping body of the mouse; and a limiting component is arranged at the joint of the round seat body and the connecting seat.
In an embodiment of the present invention, the limiting component includes two support rods arranged side by side, and the two support rods are located right above the first groove; a limit steel wire is arranged between the support rods.
In an embodiment of the invention, the tail clamping body of the mouse comprises a square frame body, a threaded hole is formed in the square frame body, a limit screw is spirally arranged on the threaded hole, and the square frame body is fixed in the second groove.
In an embodiment of the present invention, the tail clamping body of the mouse comprises a clip, two ends of the tail of the clip are respectively provided with a hinge part, and the hinge parts are fixedly arranged on the side wall of the second groove; the front end of the clip is provided with a rubber ring; the clip is disposed within the second recess.
In one embodiment of the invention, a rubber pad is arranged on the inner side of the hook-shaped opening.
In an embodiment of the present invention, the MCU is connected with a key and a display screen, and the key and the display screen are disposed on a side wall of the connection base, and the key includes an intravenous injection speed increasing key, an intravenous injection speed decreasing key, and a confirmation key.
In an embodiment of the invention, the MCU is connected with a wireless communication module, and the wireless communication module is communicated with a user mobile phone to realize the transmission instruction of the user mobile phone and the feedback of the injection state information of the mouse intravenous intelligent injection device.
In an embodiment of the invention, rails for the tail clamp of the mouse are disposed on two sides of the second groove on the connecting seat.
In one embodiment of the present invention, two drawing boxes are arranged on the circular base, wherein the first drawing box on the left side is used for placing sterilized cotton; the second drawing box on the right is used for placing disinfection alcohol; a rechargeable battery is arranged in the base, the rechargeable battery supplies power to a miniature electric pump through a switch, and the water inlet end of the miniature electric pump is communicated to the second drawing box; the output end of the miniature electric pump is connected to a needle-type spray head through a liquid guide tube; the needle head type spray head is aligned with the second groove, so that when in injection, a user starts the miniature electric pump through the switch to spray alcohol to the tail needle head insertion position of the mice; the liquid guide tube extends out from the side wall of the circular base body and is fixed on a clamping support arranged on the track.
The invention has the advantages that: the device provided by the invention can be used for carrying out intravenous injection on the mice more accurately through the functions of the injection needle driving assembly and the isolation plate, and can be used for carrying out slow injection to improve the survival rate of the mice.
Drawings
FIG. 1 is a schematic view of a first embodiment of the present invention;
fig. 2 is a schematic structural view of a separator according to a first embodiment of the present invention;
FIG. 3 is a schematic diagram of a second embodiment of the present invention;
FIG. 4 is a schematic view of the structure of a third embodiment of the present invention;
fig. 5 is a top view of a third embodiment of the present invention.
Detailed Description
The invention will be further described with reference to the accompanying drawings and examples.
As shown in fig. 1, 2, 3, 4 and 5, a white mouse weight, heart rhythm and body temperature monitoring device according to a first embodiment of the present invention includes a base 1 and a transparent hemispherical cover 2; the base 1 comprises a circular base body 11 and a connecting seat 12 connected with the side wall of the circular base body 11, one side of the transparent hemispherical cover body 2 is hinged on the circular base body 11, and a hook-shaped opening 21 is formed in the bottom of the other side of the transparent hemispherical cover body 2; so as to be beneficial to the tail of the mice 100 to extend out of the hook-shaped opening after the transparent hemispherical cover body 2 is covered; four reset posts 31 are arranged on the transparent hemispherical cover body 2 in a penetrating way, and a limiting net 32 is arranged at the end part of the reset post, which is positioned in the transparent hemispherical cover body, so that when the reset post is pressed down, the limiting net covers the mice and limits the actions of the mice; the end part of the reset column, which is positioned outside the transparent hemispherical cover body, is provided with a supporting plate 33; the arc top of the transparent hemispherical cover body is fixedly connected with a screw rod 34, the screw rod penetrates through the center of the supporting plate, and a limit screw 35 is sleeved on the screw rod. It should be noted that in this embodiment, the reset post 31 is reset by the spring 45. The circular base body comprises a hollow chassis 111 and a weighing disc 112 arranged on the hollow chassis, and a weight sensor 113 is arranged between the weighing disc 111 and the hollow chassis; the weighing disc is provided with a groove 114 in the middle, and an elastic gasket 115 is arranged in the groove and comprises a gasket 1151 and a return spring 1152 arranged below the gasket; after compression of the return spring, the gasket can be pressed into the recess 114; a USB charging interface 121 is disposed on a side wall of the base, and an output end of the USB charging interface charges the rechargeable battery 119 through a charging circuit; an annular pressure sensor 116 for detecting the heart rhythm of the mice is also arranged in the elastic gasket; an infrared temperature measuring probe 117 for detecting the body surface temperature of the mice is arranged in the middle of the annular pressure sensor; the infrared temperature measurement probe is connected with the infrared temperature measurement module through a wire 118; a rechargeable battery 119 is arranged in the hollow chassis, the rechargeable battery supplies power to a circuit board, an MCU is arranged on the circuit board 120, and the MCU is connected with the weight sensor, the annular pressure sensor and the infrared temperature measuring module; a first groove 3 is formed at the joint of the circular seat body 11 and the connecting seat 12, a second groove 4 is formed on the connecting seat 12, and the first groove 3 is connected with the second groove 4; a partition plate 5 is transversely arranged in the bottom of the connecting seat 12, and the partition plate 5 divides the inner side of the bottom of the connecting seat 12 into an upper cavity 51 and a lower cavity 52; the isolation plate 5 is provided with a square opening 53; a needle driving assembly 6 is arranged in the bottom of the connecting seat 12, and the needle driving assembly 6 comprises an asynchronous motor 61, a screw rod 62 and a squeeze plate 63; two ends of the screw rod 62 are fixed in the lower cavity 52 of the connecting seat 12, the asynchronous motor 61 is arranged in the upper cavity 51, and a rotating shaft of the asynchronous motor 61 passes through the square opening 53 to be connected with one end of the screw rod 62; the asynchronous motor is connected with the MCU through an asynchronous driving circuit, the extrusion plate 63 is longitudinally and vertically arranged and fixedly arranged on the screw rod 62, and the extrusion plate 63 can move back and forth on the square opening 53; due to the fact that the partition plate 5 is arranged to fix the screw rod 62 into the lower cavity 52, the extrusion plate 63 can extrude better, the extrusion plate 63 penetrates through the square opening 53 of the partition plate 5 to limit the extrusion plate 63 well, the injection needle cylinder 66 is not deviated in the extrusion process of the extrusion plate 63, the injection can be accurately performed, and the rubber gasket 64 is arranged on the extrusion plate 63 to perform slow injection.
A rubber gasket 64 is arranged on the front surface of the extrusion plate 63; a limiting plate 65 and an injection needle cylinder 66 are arranged in the upper cavity 51; a through hole (not shown) is formed in the limiting plate 65, the injection syringe 66 is located between the extruding plate 63 and the limiting plate 65, an injection head 661 of the injection syringe 66 passes through the through hole, a channel 7 is disposed between the upper cavity 51 and the second groove 4, an injection needle 8 is disposed on the injection head 661, and the injection needle 8 includes an injection buffer portion 81, a bending portion 82, and an injection portion 83 in sequence; the injection buffer part 81, the bending part 82 and the injection part 83 are connected in sequence; the injection part 83 passes through the channel 7, and the injection part 83 exposes out of the surface of the first groove 3; the tail part of the second groove 4 is provided with a tail clamping body 9 of the tail of the mouse; a limiting component 10 is arranged at the joint of the circular base 11 and the connecting base 12. The invention can realize slow injection of medicine, namely medicine liquid is firstly buffered in the injection buffer part 81 during injection and then is sent into the injection part 83 through the bending part 82, the bending part 83 also plays a role in buffering medicine, and the medicine can be injected in the injection part 83. In order to ensure that the medicine can be well injected into the body of a mice when the medicine is injected, an included angle A between the injection buffer part 81 and the bending part 82 is 120-140 degrees; the included angle B between the bending part 82 and the injection part 83 is 140-160 degrees; after a plurality of groups of test data, the included angle A is preferably 130 degrees, and the included angle B is preferably 150 degrees; in this case, the state of the mice after injection is the best.
The limiting assembly 10 comprises two supporting rods 101 which are arranged side by side, and the two supporting rods 101 are just above the first groove 3; a limit steel wire 102 is arranged between the support rods 101. The hook-shaped opening 21 can be hooked on the limit wire 102, so that the transparent hemispherical cover body 2 is fixed. The transparent hemispherical cover body 2 is a transparent hemispherical cover body with transparent color. This facilitates observation of the condition of the mice after injection.
Referring to fig. 1, a rubber pad 36 is disposed inside the hook-shaped opening. The tail clamping body 9 comprises a square frame body 94, a threaded hole (not shown) is formed in the square frame body 94, a limit screw 95 is arranged on the threaded hole in a screwed mode, and the square frame body 94 is fixed in the second groove 4. The tail of the mouse is passed through the square frame 94 and is restrained and fixed by the rotating screw 95.
Referring to fig. 3, the tail clamp 9 includes a clip 91, two ends of the tail of the clip 91 are respectively provided with a hinge portion 92, and the hinge portions 92 are fixedly disposed on the side wall of the second groove 4; the clip 91 is capable of articulating through the articulating portion 92; the front end of the clip 91 is provided with a rubber ring 93; the rubber ring 93 can clamp the tail of the mouse well, and the tail cannot be broken; the clip 91 is disposed in the second recess 4.
In an embodiment of the present invention, the asynchronous motor is connected to an MCU through an asynchronous driving circuit, the MCU is connected to a key and a display screen, the key and the display screen are disposed on a side wall of the connection seat (not shown in the key and the display screen), and the key includes an intravenous injection speed increasing key, an intravenous injection speed reducing key and a confirmation key; the user can set the device through the key, and state information can be obtained through observing the display screen.
In an embodiment of the invention, the MCU is connected with a wireless communication module, and the wireless communication module is communicated with a user mobile phone to realize the transmission instruction of the user mobile phone and the feedback of the injection state information of the mouse intravenous intelligent injection device. The function not only can ensure that a user realizes long-distance detection, but also can modify setting information through a mobile phone of the user at any time, so that real-time monitoring and reminding are realized.
Please refer to fig. 1 and 5; in an embodiment of the present invention, the rails 42 for the tail clamp 9 are disposed on the connecting seat at two sides of the second groove. In one embodiment of the present invention, two drawing boxes are disposed on the circular base, wherein the first drawing box 37 on the left is used for placing sterilized cotton; the second drawer 38 on the right is used for placing sterilizing alcohol; in this embodiment, both the drawer 37 and the second drawer 38 are provided with a hand pull 44; a rechargeable battery is arranged in the first base, the rechargeable battery supplies power to a micro electric pump 39 through a switch, and the water inlet end of the micro electric pump is communicated to the second drawing box; the output end of the micro-electric pump is connected to a needle-type nozzle 41 through a liquid guiding tube 40; the needle type spray head is aligned to the second groove, so that when in injection, a user starts the micro electric pump through a switch (not shown) to spray alcohol to the tail needle insertion position of the mice; the catheter extends from the side wall of the circular housing and is fixed to a clamping bracket 43 provided on the track 42. A USB charging interface 46 is disposed on a side wall of the base, and an output end of the USB charging interface charges the rechargeable battery 47 through a charging circuit.
In an embodiment of the present invention, an opening (not shown) for placing the syringe into the upper cavity is provided on a side wall of the connection base.
In a word, the invention automatically carries out intravenous injection on the mice through the injection needle driving component; the white mouse with the clamping body can be observed in the round seat body with the transparent hemispherical cover body after injection, the operation is simple, and the working efficiency is improved. Intravenous injection is more accurate on the mice under the action of the injection needle driving assembly and the isolation plate, and slow injection can be performed, so that the survival rate of the mice is improved; in addition, the invention skillfully arranges a weighing sensor, a temperature acquisition sensor and a heart rhythm detection sensor on the base; the mouse vital sign data can be monitored before and after injection, so that the efficiency of a mouse experiment can be improved, and the reliability of the experiment data is greatly improved.
The foregoing description is only of the preferred embodiments of the invention, and all changes and modifications that come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Claims (4)
1. A white mouse weight, rhythm of heart, body temperature monitoring devices, its characterized in that: comprises a base and a transparent hemispherical cover body; the base comprises a round base body and a connecting seat connected with the side wall of the round base body, one side of the transparent hemispherical cover body is hinged on the round base body, and a hook-shaped opening is formed in the bottom of the other side of the transparent hemispherical cover body; the tail of the mice stretches out of the hooked opening after the transparent hemispherical cover body is covered; four reset posts penetrate through the transparent hemispherical cover body, and a limiting net is arranged at the end parts of the four reset posts, which are positioned in the transparent hemispherical cover body, and is used for covering the mice when the reset posts are pressed down, so as to limit the actions of the mice; the end parts of the four reset posts, which are positioned outside the transparent hemispherical cover body, are provided with a supporting plate; the arc top of the transparent hemispherical cover body is fixedly connected with a screw rod, the screw rod passes through the center of the supporting plate, and a first limit screw is sleeved on the screw rod; the circular base body comprises a hollow chassis and a weighing disc arranged on the hollow chassis, and a weight sensor is arranged between the weighing disc and the hollow chassis; the middle part of the weighing disc is provided with a groove, an elastic gasket is arranged in the groove, and an annular pressure sensor for detecting the heart rhythm of the mice is arranged in the elastic gasket; an infrared temperature measuring probe for detecting the body surface temperature of the mice is arranged in the middle of the annular pressure sensor; the elastic gasket comprises a gasket and a return spring arranged below the gasket; after the reset spring is compressed, the gasket can be pressed into the groove; the infrared temperature measuring probe is connected with the infrared temperature measuring module through a wire; a first rechargeable battery is arranged in the hollow chassis, the first rechargeable battery supplies power for a circuit board, an MCU is arranged on the circuit board, and the MCU is connected with the weight sensor, the annular pressure sensor and the infrared temperature measuring module; a first groove is formed in the joint of the circular base body and the connecting base, a second groove is formed in the connecting base, and the first groove is connected with the second groove; a partition plate is transversely arranged in the bottom of the connecting seat, and divides the inner side of the bottom of the connecting seat into an upper cavity and a lower cavity; the isolation plate is provided with a square opening; the bottom of the connecting seat is internally provided with an injection needle driving assembly, and the injection needle driving assembly comprises an asynchronous motor, a screw rod and an extrusion plate; the two ends of the screw rod are fixed in the lower cavity of the connecting seat, the asynchronous motor is arranged in the upper cavity, and a rotating shaft of the asynchronous motor penetrates through the square opening to be connected with one end of the screw rod; the asynchronous motor is connected with the MCU through an asynchronous driving circuit, the extrusion plate is longitudinally and vertically arranged and fixedly arranged on the screw rod, and the extrusion plate can move back and forth on the square opening; a rubber gasket is arranged on the front surface of the extrusion plate; a limiting plate and an injection needle cylinder are arranged in the upper cavity; the injection needle cylinder is positioned between the extrusion plate and the limiting plate, an injection head of the injection needle cylinder penetrates through the through hole, a channel is arranged between the upper cavity and the second groove, an injection needle is arranged on the injection head, and the injection needle comprises an injection buffer part, a bending part and an injection part; the injection buffer part, the bending part and the injection part are connected in sequence; an included angle formed between the injection buffer part and the bending part is 120-140 degrees; the included angle formed between the bending part and the injection part is 140-160 degrees; the injection part passes through the channel, and the injection part is exposed out of the surface of the first groove; the tail part of the second groove is provided with a tail clamping body of the mouse; a limiting component is arranged at the joint of the round seat body and the connecting seat; the rails for the tail clamping body of the mouse are arranged on the two sides of the second groove on the connecting seat; two drawing boxes are arranged on the round seat body, wherein the first drawing box on the left side is used for placing disinfection cotton; the second drawing box on the right is used for placing disinfection alcohol; a second rechargeable battery is arranged in the base, the second rechargeable battery supplies power to a micro electric pump through a switch, and the water inlet end of the micro electric pump is communicated to the second drawing box; the output end of the miniature electric pump is connected to a needle-type spray head through a liquid guide tube; the needle head type spray head is aligned to the second groove, so that when in injection, a user starts the miniature electric pump through the switch to spray disinfection alcohol to the tail needle head insertion position of the mice; the liquid guide tube extends out of the side wall of the circular seat body and is fixedly arranged on the clamping bracket on the track; the limiting assembly comprises two supporting rods which are arranged side by side, and the two supporting rods are positioned above the first groove; a limit steel wire is arranged between the two support rods; the MCU is connected with a key and a display screen, the key and the display screen are arranged on the side wall of the connecting seat, and the key comprises an intravenous injection speed increasing key, an intravenous injection speed reducing key and a confirmation key; the MCU is connected with a wireless communication module, and the wireless communication module is communicated with a user mobile phone to realize the transmission instruction of the user mobile phone and the feedback of the injection state information of the white mouse weight, heart rhythm and body temperature monitoring device.
2. The device for monitoring body weight, heart rhythm and body temperature of mice according to claim 1, wherein: the tail clamping body of the mouse comprises a square frame body, a threaded hole is formed in the square frame body, a second limit screw is arranged on the threaded hole in a spiral mode, and the square frame body is fixed in the second groove.
3. The device for monitoring body weight, heart rhythm and body temperature of mice according to claim 1, wherein: the tail clamping body of the mouse comprises a clamp, two ends of the tail of the clamp are respectively provided with a hinge part, and the two hinge parts are fixedly arranged on the side wall of the second groove; the front end of the clip is provided with a rubber ring; the clip is disposed within the second recess.
4. The device for monitoring body weight, heart rhythm and body temperature of mice according to claim 1, wherein: a rubber pad is arranged on the inner side of the hook-shaped opening.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610672411.4A CN106264508B (en) | 2016-08-16 | 2016-08-16 | Body weight, heart rhythm and body temperature monitoring device for mice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610672411.4A CN106264508B (en) | 2016-08-16 | 2016-08-16 | Body weight, heart rhythm and body temperature monitoring device for mice |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106264508A CN106264508A (en) | 2017-01-04 |
| CN106264508B true CN106264508B (en) | 2024-03-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610672411.4A Active CN106264508B (en) | 2016-08-16 | 2016-08-16 | Body weight, heart rhythm and body temperature monitoring device for mice |
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| CN (1) | CN106264508B (en) |
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| CN111912504B (en) * | 2020-07-30 | 2022-05-13 | 温州医科大学附属第一医院 | Mouse weighing device for pharmacology experiments |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1282566A (en) * | 1999-08-02 | 2001-02-07 | 中国药科大学 | Method and equipment for indirectly measuring blood pressure by rat tail pulses |
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| CN205379384U (en) * | 2016-01-19 | 2016-07-13 | 张晓光 | Auxiliary device for caudal vein injection and blood sampling of mice |
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| CN1282566A (en) * | 1999-08-02 | 2001-02-07 | 中国药科大学 | Method and equipment for indirectly measuring blood pressure by rat tail pulses |
| CN202437394U (en) * | 2012-01-19 | 2012-09-19 | 德州学院 | Administration device capable of expanding caudal veins of mouse |
| CN202740008U (en) * | 2012-06-12 | 2013-02-20 | 上海瑞曼信息科技有限公司 | Automatic sampling and dosing system for animals |
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| CN204446167U (en) * | 2015-01-14 | 2015-07-08 | 苏州大学 | Mouse tail vein injection experimental provision |
| CN105342576A (en) * | 2015-11-12 | 2016-02-24 | 赵增友 | Pet telecommunication network solar energy body temperature monitoring acquisition positioning unit |
| CN205379384U (en) * | 2016-01-19 | 2016-07-13 | 张晓光 | Auxiliary device for caudal vein injection and blood sampling of mice |
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| CN106264508A (en) | 2017-01-04 |
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