CN111912504B - Mouse weighing device for pharmacology experiments - Google Patents
Mouse weighing device for pharmacology experiments Download PDFInfo
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- CN111912504B CN111912504B CN202010751692.9A CN202010751692A CN111912504B CN 111912504 B CN111912504 B CN 111912504B CN 202010751692 A CN202010751692 A CN 202010751692A CN 111912504 B CN111912504 B CN 111912504B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01G—WEIGHING
- G01G17/00—Apparatus for or methods of weighing material of special form or property
- G01G17/08—Apparatus for or methods of weighing material of special form or property for weighing livestock
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01G—WEIGHING
- G01G23/00—Auxiliary devices for weighing apparatus
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Abstract
The invention provides a white mouse weighing device for pharmacological experiments, and belongs to the technical field of medical equipment. It has solved the inaccurate problem of current mice weighing. The invention comprises an electronic scale and a weighing box, wherein a pressing plate is horizontally arranged in the weighing box, a first row of teeth and a second row of teeth are respectively arranged at the gaps at the two sides of the pressing plate, clamping bars on the first row of teeth and the second row of teeth are sequentially and alternately arranged, a first rotating shaft and a second rotating shaft which are rotatably connected with the weighing box and are parallel to each other are arranged below the pressing plate, the first row of teeth and the second row of teeth can be reversely turned around the corresponding rotating shafts under the action of a reset mechanism so as to form a throwing opening at the upper part, and when the pressing plate moves downwards, the first row of teeth and the second row of teeth can be driven to be oppositely turned and furled around the corresponding rotating shafts through a first connecting rod and a second connecting rod to form a furling channel. According to the invention, through the two groups of tooth arrangement structures, the mice can be tightly raked automatically after being thrown in, the movement of the mice is limited, the weighing stability and accuracy are ensured, and the operation is simple and convenient.
Description
Technical Field
The invention belongs to the technical field of medical equipment, and relates to a white mouse weighing device for pharmacological experiments.
Background
In the experiment using the white mouse, because the white mouse is easy to be raised, has high reproduction rate and higher genetic purity, the metabolic type and the physiological pathology are close to the human being as much as possible, the gene sequence of the white mouse is similar to the human being, and some medical scientific researches and clinical experiments are completed by the white mouse. In the middle of the experiment, the white mouse is best for genetic experiments because the similarity between the whole genome and human is extremely high, the chromosome of the white mouse is very close to that of the human, and in addition, the stability of the genetic genes of the white mouse and the pure white mouse in the same litter have almost the same genetic characteristics, which is very convenient for scientific experiments and eliminates the difference of individual objects.
In the research process of novel medicines, pharmacological experiments can be used for measuring the basic action of medicines, different physicochemical properties of the medicines, the influence of elements such as different dosages on the action of the medicines, and the like, and as the chromosome and the human body of a white mouse are very close to the resistance and the absorption capacity of most medicines to the human body, the white mouse is usually selected for experiments in the prior step of the pharmacological experiments; a common thing to do before and after pharmacological experiments is to weigh the weight of the mice.
However, in the actual use process, since most of mice are living, the mice are inevitably shaken when weighed in a fresh environment, and stable weight data is difficult to obtain.
Disclosure of Invention
The invention aims to solve the problems existing in the conventional mouse weighing, and provides a weighing device which is convenient to weigh and can automatically limit the moving range of a mouse.
The purpose of the invention can be realized by the following technical scheme:
a white mouse weighing device for pharmacology experiments comprises an electronic scale and a weighing box, wherein the weighing box is arranged on the electronic scale, the top of the weighing box is provided with an opening, the side part of the weighing box is provided with an outlet, and the outlet is provided with a cover door, the white mouse weighing device is characterized in that a pressing plate is horizontally arranged in the weighing box and divides an inner cavity of the weighing box into an upper cavity and a lower cavity, gaps are reserved between two side edges of the pressing plate and the inner wall of the weighing box, a first row of teeth and a second row of teeth are respectively arranged at the positions of the gaps at two sides of the pressing plate, the first row of teeth and the second row of teeth comprise fixing rods and a plurality of arc-shaped clamping strips, the plurality of arc-shaped clamping strips are arranged at intervals along the corresponding fixing rods, one ends of the clamping strips are fixedly connected with the corresponding fixing rods, the other ends of the clamping strips extend in a bending manner from the upper side of the pressing plate to the row of teeth at the other side, the clamping strips on the first row of teeth and the second row of teeth are sequentially and alternately arranged, a first rotating shaft and a second rotating shaft which are parallel to the weighing box are arranged below the pressing plate, the first rotating shaft is fixedly provided with a first connecting rod, the first connecting rod is vertically and fixedly connected with the first rotating shaft, one end of the first connecting rod is fixedly connected with a first fixing rod, the other end of the first connecting rod is abutted against the lower end face of the pressing plate, the second rotating shaft is fixedly provided with a second connecting rod, the second connecting rod is vertically and fixedly connected with the second rotating shaft, one end of the second connecting rod is fixedly connected with a second fixing rod, the other end of the second connecting rod is abutted against the lower end face of the pressing plate, the first row of teeth and the second row of teeth can be overturned around the corresponding rotating shafts respectively in a reverse direction to form a putting opening at the upper part under the action of the reset mechanism, when the pressing plate moves downwards, the first row of teeth and the second row of teeth can be driven to overturn around the corresponding rotating shafts respectively through the first connecting rod and the second connecting rod in a reverse direction to form a drawing channel, and one end of the drawing channel is aligned to the outlet.
In the white mouse weighing device for pharmacological experiments, a plurality of guide columns are vertically arranged in the weighing box, the guide columns penetrate through the pressure plate, and the pressure plate can freely reciprocate along the guide columns.
In the white mouse weighing device for pharmacological experiments, the reset mechanism is a plurality of reset springs, the reset springs are sleeved on the guide columns in a one-to-one correspondence manner, the upper ends of the reset springs act on the lower end face of the pressing plate, and the lower ends of the reset springs act on the bottom of the weighing box.
In the white mouse weighing device for pharmacological experiments, the first connecting rod and the second connecting rod respectively comprise a rod sleeve and an adjusting rod, the rod sleeves are hollow and are fixedly connected with the corresponding rotating shafts and the corresponding fixing rods, the adjusting rods are arranged in the corresponding rod sleeves, the outer ends of the adjusting rods extend out of the sleeve rods and abut against the lower end face of the pressing plate, and the adjusting rods can freely move along the rod sleeves to adjust the extension degree.
In the white mouse weighing device for pharmacological experiments, the lower end surface of the pressure plate is provided with a plurality of parallel guide grooves, the extending end of the adjusting rod is rotatably provided with a roller, and the roller is clamped in the corresponding guide groove.
In the white mouse weighing device for pharmacological experiments, a partition plate is further arranged below the pressure plate, two ends of the partition plate are fixedly connected with the weighing box, the resetting mechanism is a balancing weight, and the upper ends of the first connecting rod and the second connecting rod penetrate through the partition plate and abut against the lower end face of the pressure plate.
In the white mouse weighing device for pharmacological experiments, the pressure plate is provided with the hollow part, the dirt drawer is arranged below the pressure plate in the weighing box, and the side wall of the weighing box is provided with the drawing opening capable of drawing the dirt drawer away.
Compared with the prior art, the invention can automatically hug the mice tightly after the mice are put into the device by the two groups of tooth-arranging structures, so as to limit the movement of the mice, ensure the stability and accuracy of weighing and have simple and convenient operation. The folding amplitude can be adjusted according to the mouse body type, and the mouse is flexible and changeable and has wide adaptability. After the mice are weighed, the mice can be discharged by opening the cover door, the row teeth are automatically opened, the next weighing operation of the mice can be immediately carried out, and the efficiency is high.
Drawings
Fig. 1 is a schematic structural view of the present invention.
FIG. 2 is a schematic view of the present invention with the case removed.
FIG. 3 is a schematic view of the first and second rows of teeth in their collapsed condition.
Fig. 4 is a schematic view of the first and second rows of teeth in an open position.
In the figure, 1, a box body; 2. an outlet; 3. pressing a plate; 4. a first row of teeth; 5. a second row of teeth; 6. clamping strips; 7. fixing the rod; 8. a first rotating shaft; 9. a second rotating shaft; 10. a first link; 11. a second link; 12. a guide post; 13. a throwing port; 14. collecting the channel; 15. a rod sleeve; 16. adjusting a rod; 17. a return spring.
Detailed Description
The following are specific embodiments of the present invention and are further described with reference to the drawings, but the present invention is not limited to these embodiments.
As shown in fig. 1, the mouse weighing apparatus for pharmacological experiments includes an electronic scale and a weighing box, the weighing box is placed on the electronic scale (not shown), and the electronic scale may be a general electronic scale or other types of scales.
The weighing box is a box body 1 with an inner cavity inside, the top of the box body 1 is provided with an opening, the side of the box body is provided with an outlet 2, the outlet 2 is provided with a cover door (not shown in the figure), the cover door can be in a sliding door shape and is in sliding connection with the box body 1, the cover door falls under the action of dead weight at ordinary times, the outlet 2 is covered and closed, and the cover door is lifted upwards to open the outlet 2 when needed.
As shown in fig. 2, a pressing plate 3 is horizontally and fixedly arranged in the weighing box, the length of the pressing plate 3 is close to that of the box body 1, the gap between the two ends of the pressing plate and the box body 1 is reduced as much as possible, the width of the pressing plate 3 is about half of that of the box body 1, so that sufficient gaps are formed between the two sides of the pressing plate 3 and the inside of the box body 1, and meanwhile, the pressing plate 3 divides the inner cavity of the weighing box into an upper cavity and a lower cavity.
The clearance department of 3 both sides of clamp plate has set up first row of tooth 4 and second row of tooth 5 respectively, first row of tooth 4 and second row of tooth 5 all include dead lever 7 and many arc holding strip 6, many arc holding strip 6 are along corresponding 7 interval arrangements of dead lever, dead lever 7 is located clamp plate 3 below and is close to corresponding clearance department, the one end of holding strip 6 with correspond dead lever 7 fixed connection, the other end is worn from the clearance department and is come and cross 3 crooked extensions of row's tooth direction of clamp plate to the opposite side, holding strip 6 on first row of tooth 4 and the second row of tooth 5 staggers in proper order.
The lower part of the pressing plate 3 is also provided with a first rotating shaft 8 and a second rotating shaft 9 which are rotatably connected with the weighing box and are parallel to each other, a first connecting rod 10 is fixedly arranged on the first rotating shaft 8, the first connecting rod 10 is vertically and fixedly connected with the first rotating shaft 8, one end of the first connecting rod is fixedly connected with the first fixing rod 7, and the other end of the first connecting rod abuts against the lower end face of the pressing plate 3. A second connecting rod 11 is fixedly arranged on the second rotating shaft 9, the second connecting rod 11 is vertically and fixedly connected with the second rotating shaft 9, one end of the second connecting rod is fixedly connected with the second fixing rod 7, the other end of the second connecting rod is abutted against the lower end face of the pressing plate 3, the first connecting rod 10 and the second connecting rod 11 are provided with a plurality of connecting rods, and the connecting rods are arranged at intervals in parallel and staggered alternately.
A plurality of guide columns 12 are vertically arranged in the weighing box, the guide columns 12 penetrate through the pressure plate 3, and the pressure plate 3 can freely reciprocate along the guide columns 12.
As shown in fig. 4, the first row of teeth 4 and the second row of teeth 5 can be turned over around their corresponding rotating shafts in a back-to-back manner when no foreign object acts on them, and the upper portions of the teeth are opened to form the putting-in opening 13. At this time, the platen 3 is also lifted by the first link 10 and the second link 11.
A mouse to be weighed is put into the pressing plate 3 from the putting-in opening 13, the pressing plate 3 moves downwards under the action of the gravity of the mouse, the first row of teeth 4 and the second row of teeth 5 are folded by rotating around the corresponding rotating shafts through the first connecting rod 10 and the second connecting rod 11, the putting-in opening 13 is closed, the folding channel 14 is formed, the clamping strips 6 are staggered, the mouse is held and can not turn, and the first row of teeth 4 and the second row of teeth 5 are kept in a folded state without leaving the pressing plate 3.
And then, directly reading the data of the electronic scale (zero clearing is carried out before the mouse is put in), namely the weight of the mouse, and reading for several times to obtain an average value, which is relatively more accurate. After weighing is finished, the cover door is opened, and a mouse is drilled out of the cover door by utilizing the drilling characteristic of the mouse because the furling channel 14 is opposite to the cover door. After the mouse leaves the pressing plate 3, the pressing plate 3 is reset and lifted, and the first row of teeth 4 and the second row of teeth 5 are reset and opened again for the next mouse to throw in.
As shown in fig. 3, the reset of the first row of teeth 4 and the second row of teeth 5 can utilize self eccentric dead weight, the gravity center is at the outer side of the corresponding rotating shaft, and after the white mouse leaves the pressing plate 3, the first row of teeth 4 and the second row of teeth 5 turn over outwards and reset under the action of self gravity. Or the return springs 17 are adopted, the return springs 17 are sleeved on the guide columns 12 in a one-to-one correspondence mode, the upper ends of the return springs 17 act on the lower end face of the pressing plate 3, and the lower ends of the return springs act on the bottom of the weighing box. When the mouse falls on the pressing plate 3, the reset spring 17 is compressed, when the mouse leaves the pressing plate 3, the reset spring 17 resets to jack up the pressing plate 3, and the two side edges of the pressing plate 3 can act on the arc-shaped inner edge of the holding strip 6 to jack the first row of teeth 4 and the second row of teeth 5 to the two sides.
In order to prevent the first row of teeth 4 and the second row of teeth 5 from being too small to be drawn in and blocking the white mouse from drilling out, a partition plate can be arranged below the pressure plate 3, the shape of the partition plate is similar to that of the pressure plate 3, two ends of the partition plate are fixedly connected with the weighing box, a gap is formed between the side edge and the weighing box, and when the pressure plate 3 goes down, the partition plate can block the space to limit the drawing stroke of the first row of teeth 4 and the second row of teeth 5, so that the white mouse cannot be drawn in too tightly. In this embodiment, the first row of teeth 4 and the second row of teeth 5 are preferably reset in the form of self-weight, and a counter weight may be provided if necessary. At this time, it is necessary to form a strip-shaped through hole on the partition plate, and the upper ends of the first connecting rod 10 and the second connecting rod 11 pass through the through holes and abut against the lower end surface of the pressure plate 3.
Aiming at the possible great difference of the sizes of mice of different batches, the invention can also adjust the furling amplitude of the first row of teeth 4 and the second row of teeth 5. The adjustment mode is as follows: the first connecting rod 10 and the second connecting rod 11 both comprise rod sleeves 15 and adjusting rods 16, the rod sleeves 15 are hollow and are fixedly connected with corresponding rotating shafts and the fixing rods 7, the adjusting rods 16 are arranged in the corresponding rod sleeves 15, the outer ends of the extending rod sleeves abut against the lower end face of the pressing plate 3, and the adjusting rods 16 can freely move along the rod sleeves 15 to adjust the extending degree. The adjustment lever 16 may be threaded with the lever sleeve 15 or may have a multi-speed bayonet lock disposed therebetween. The farther the distance of the rotary shaft from the abutment point on the pressure plate 3, the greater the turnover amplitude of the row of teeth and the smaller the gathering channel 14.
The lower end surface of the pressing plate 3 is provided with a plurality of parallel guide grooves, the extending end of the adjusting rod 16 is rotatably provided with a roller wheel, and the roller wheel is clamped in the corresponding guide groove.
Weigh the in-process, sometimes can take place the excreted condition of mice, can be hollow out construction with clamp plate 3 and baffle setting, the below that is located clamp plate 3 in the case of weighing sets up the filth drawer, and the case lateral wall of weighing is opened has the extraction opening that can take out this filth drawer and leave. After weighing is finished, the dirt drawer can be drawn out for weighing, and the weight of the dirt drawer is subtracted to obtain the dirt amount. When the body weight of the white mouse is counted, the dirt amount needs to be subtracted to obtain the actual body weight of the white mouse.
It is to be understood that in the claims, specification of the invention, all "including … …" are to be interpreted in an open-ended sense, i.e. in a sense equivalent to "including at least … …", and not in a closed sense, i.e. in a sense not to be interpreted as "including … … only".
The specific embodiments described herein are merely illustrative of the spirit of the invention. Various modifications or additions may be made to the described embodiments or alternatives may be employed by those skilled in the art without departing from the spirit or ambit of the invention as defined in the appended claims.
Claims (5)
1. A white mouse weighing device for pharmacology experiments comprises an electronic scale and a weighing box, wherein the weighing box is arranged on the electronic scale, the top of the weighing box is provided with an opening, the side part of the weighing box is provided with an outlet (2), and the outlet (2) is provided with a cover door, the white mouse weighing device is characterized in that a pressure plate (3) is horizontally arranged in the weighing box, the pressure plate (3) divides an inner cavity of the weighing box into an upper cavity and a lower cavity, gaps are reserved between two side edges of the pressure plate (3) and the inner wall of the weighing box, gaps on two sides of the pressure plate (3) are respectively provided with a first row of teeth (4) and a second row of teeth (5), the first row of teeth (4) and the second row of teeth (5) respectively comprise fixing rods (7) and a plurality of arc-shaped clamping strips (6), the plurality of arc-shaped clamping strips (6) are arranged at intervals along the corresponding fixing rods (7), the fixing rods (7) are positioned below the pressure plate (3) and close to the corresponding gaps, one ends of the clamping strips (6) are fixedly connected with the corresponding fixing rods (7), the other end of the pressing plate (3) is bent and extended towards the tooth arrangement direction of the other side from the upper part of the pressing plate (3), clamping strips (6) on a first row of teeth (4) and a second row of teeth (5) are sequentially and alternately arranged, a first rotating shaft (8) and a second rotating shaft (9) which are rotationally connected with the weighing box and are parallel to each other are arranged below the pressing plate (3), a first connecting rod (10) is fixedly arranged on the first rotating shaft (8), the first connecting rod (10) is vertically and fixedly connected with a first rotating shaft (8) rod, one end of the first connecting rod is fixedly connected with a first fixing rod (7), the other end of the first connecting rod abuts against the lower end face of the pressing plate (3), a second connecting rod (11) is fixedly arranged on the second rotating shaft (9), the second connecting rod (11) is vertically and fixedly connected with a second rotating shaft (9) rod, one end of the second connecting rod (7) is fixedly connected with the other end of the second fixing rod, the other end of the second connecting rod abuts against the pressing plate (3), the first row of teeth (4) and the second row of teeth (5) can be turned back around the corresponding rotating shaft under the action of the resetting mechanism to turn over the upper part, so as to turn over the first row of the teeth (4) and the second row of the second row teeth (5) in order to turn over the upper part The pressing plate (3) can drive the first row of teeth (4) and the second row of teeth (5) to oppositely turn and furl around the corresponding rotating shafts through the first connecting rod (10) and the second connecting rod (11) to form a furling channel (14) when moving downwards, and one end of the furling channel (14) is opposite to the outlet (2);
a plurality of guide columns (12) are also vertically arranged in the weighing box, the guide columns (12) penetrate through the pressure plate (3), and the pressure plate (3) can freely reciprocate along the guide columns (12);
the reset mechanism is provided with a plurality of reset springs (17), the reset springs (17) are sleeved on the guide columns (12) in a one-to-one correspondence mode, the upper ends of the reset springs (17) act on the lower end face of the pressure plate (3), and the lower ends of the reset springs act on the bottom of the weighing box.
2. The white mouse weighing device for the pharmacology experiment as recited in claim 1, wherein each of the first connecting rod (10) and the second connecting rod (11) comprises a rod sleeve (15) and an adjusting rod (16), the rod sleeve (15) is hollow and is fixedly connected with a corresponding rotating shaft and a corresponding fixing rod (7), the adjusting rod (16) is arranged in the corresponding rod sleeve (15), the outer end of the adjusting rod extends out of the sleeve rod and abuts against the lower end face of the pressing plate (3), and the adjusting rod (16) can freely move along the rod sleeve (15) to adjust the extending degree.
3. A mouse weighing apparatus for pharmacological experiments according to claim 2, wherein the lower end surface of the pressing plate (3) is provided with a plurality of parallel guide grooves, and the extending end of the adjusting rod (16) is rotatably provided with a roller which is clamped in the corresponding guide groove.
4. The rat weighing device for the pharmacology experiment as claimed in claim 1, wherein a partition plate is further arranged below the pressure plate (3), two ends of the partition plate are fixedly connected with the weighing box, the resetting mechanism is a balancing weight, and the upper ends of the first connecting rod (10) and the second connecting rod (11) penetrate through the partition plate and abut against the lower end face of the pressure plate (3).
5. The white mouse weighing device for the pharmacology experiment as claimed in claim 4, wherein the pressure plate (3) is hollowed, a dirt drawer is arranged below the pressure plate (3) in the weighing box, and a drawing opening capable of drawing the dirt drawer away is formed in the side wall of the weighing box.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010751692.9A CN111912504B (en) | 2020-07-30 | 2020-07-30 | Mouse weighing device for pharmacology experiments |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010751692.9A CN111912504B (en) | 2020-07-30 | 2020-07-30 | Mouse weighing device for pharmacology experiments |
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| CN111912504A CN111912504A (en) | 2020-11-10 |
| CN111912504B true CN111912504B (en) | 2022-05-13 |
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| JP2007306860A (en) * | 2006-05-19 | 2007-11-29 | Melquest:Kk | Apparatus for automatically measuring amount of feeding |
| JP2010266289A (en) * | 2009-05-13 | 2010-11-25 | Star Engineering Co Ltd | Weight-measuring and recording apparatus for small experimental animal |
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