CN106093370B - A kind of small white mouse experimental monitoring device - Google Patents

A kind of small white mouse experimental monitoring device Download PDF

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Publication number
CN106093370B
CN106093370B CN201610672160.XA CN201610672160A CN106093370B CN 106093370 B CN106093370 B CN 106093370B CN 201610672160 A CN201610672160 A CN 201610672160A CN 106093370 B CN106093370 B CN 106093370B
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small white
white mouse
groove
monitoring device
cover body
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CN106093370A (en
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卢丽花
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Kanglong Huacheng (Beijing) Biotechnology Co., Ltd.
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卢丽花
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01GWEIGHING
    • G01G19/00Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups
    • G01G19/44Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for weighing persons
    • G01G19/50Weighing apparatus or methods adapted for special purposes not provided for in the preceding groups for weighing persons having additional measuring devices, e.g. for height
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The present invention relates to a kind of small white mouse experimental monitoring device, including a base and a transparent hemispherical cover body;The base includes the connecting seat of a circular pedestal and connection circular seat body sidewall, and the circular pedestal includes hollow chassis and the weighing pan being arranged in hollow chassis, weight sensor is provided between the weighing pan and hollow chassis;The side of the transparent hemispherical cover body, which is hinged, to be arranged on circular pedestal, and another side bottom of the transparent hemispherical cover body is provided with a hook openings;The junction of the circular pedestal and connecting seat offers and the second groove is offered on one first groove, the connecting seat, and first groove is connected with the second groove;The afterbody of second groove is provided with a small white mouse tail cramping body;A limit assembly is provided with the junction of the circular pedestal and connecting seat.Small white mouse can be placed in circular seat body by the present invention, be injected intravenously, and can detect the weight of small white mouse, monitor the rhythm of the heart and body temperature of small white mouse in real time.

Description

A kind of small white mouse experimental monitoring device
Technical field
The present invention relates to field of medical technology, more particularly to a kind of small white mouse experimental monitoring device.
Background technology
It is existing to be required for carrying out drug test to small white mouse in field of medical technology, so that it is determined that the effect of medicine.Than The thing more often operated, by being observed after carrying out intravenous (IV) drug to small white mouse small white mouse, it is necessary in time in observation Record small white mouse heartbeat and the change etc. of body temperature, and also small white mouse is weighed before the injection, record its big It is small;The mode of conventional injection is all to pick up small white mouse manually, or is picked up by complicated equipment, then is injected intravenously, and is noted Pick up to be placed into another container again after penetrating and observed, so move about and add workload.
The content of the invention
It is simple in construction it is an object of the invention to provide a kind of small white mouse experimental monitoring device, and injection is convenient, can obtain The information such as weight, the rhythm of the heart and the body temperature of small white mouse;Small white mouse situation can be directly observed after injection, without small white mouse is moved to Observed in another container.
What the present invention was realized in:A kind of small white mouse experimental monitoring device, it is characterised in that:It is saturating including a base and one Bright hemispherical cover body;The base includes the connecting seat of a circular pedestal and connection circular seat body sidewall, the circular pedestal bag Hollow chassis and the weighing pan being arranged in hollow chassis are included, weight sensing is provided between the weighing pan and hollow chassis Device;Having in a groove, the groove to be provided with to set in an elastomeric pad, the elastomeric pad in the middle part of the weighing pan also has The one annular pressure sensor for detecting the small white mouse rhythm of the heart;One is provided with the middle part of the annular pressure sensor is used to detect The infrared temperature probe of small white mouse shell temperature;The infrared temperature probe is connected through wire with infrared measurement of temperature module;In described A rechargeable battery is provided with empty chassis, described rechargeable battery is powered for a circuit board, and MCU is provided with the circuit board, The MCU is connected with weight sensor, annular pressure sensor and infrared measurement of temperature module;The one of the transparent hemispherical cover body Side, which is hinged, to be arranged on circular pedestal, and another lateral edge portion of the transparent hemispherical cover body is provided with a hook openings, with profit The tail for covering the rear small white mouse in transparent hemispherical cover body is stretched out by the hook openings;The circular pedestal and connecting seat Junction offers and the second groove is offered on one first groove, the connecting seat, and first groove is connected with the second groove Connect;The afterbody of second groove is provided with a small white mouse tail cramping body;Track is provided with the connecting seat, for described Small white mouse tail cramping body is moved forward and backward on that track;It is spacing that one is provided with the junction of the circular pedestal and connecting seat Component;Four reset posts are equipped with described transparent hemispherical cover body, the reset post is located in transparent hemispherical cover body End sets a spacing net, when being pushed to the reset post, and the spacing guard lives small white mouse, limits the action of small white mouse;Institute State end of the reset post outside transparent hemispherical cover body and be provided with a supporting plate;The arc top of the transparent hemispherical cover body is fixed A screw rod is connected with, the screw rod passes through the supporting plate center, and a limited screw is arranged with the screw rod.
In an embodiment of the present invention, described elastomeric pad includes a pad and the reset bullet being arranged under pad Spring;After back-moving spring compression, the pad can be pressed into described groove.
In an embodiment of the present invention, a USB charging inlets, the USB chargings are provided with the side wall of the base The charged circuit of output end of mouth is that the rechargeable battery charges.
In an embodiment of the present invention, the connecting seat be rubber connecting seat, rubber connecting seat can deviously with the circle Shape pedestal is connected.
In an embodiment of the present invention, the small white mouse tail cramping body is included on a square frame, the square frame Offer spiral on a screwed hole, the screwed hole and be provided with a manual screw, the square frame is fixed in the second groove.
In an embodiment of the present invention, the limit assembly includes two support bars being arranged side by side, and two support bars It is located exactly at the top of the first groove;Being set up between the support bar has a spacing steel wire.
In an embodiment of the present invention, the inwall of the hook openings is provided with a resilient rubbber cushion.
In an embodiment of the present invention, the first pull of two drawing boxs, the wherein left side is provided with the circular pedestal Box is used to place aseptic cotton;Second drawing box on the right is used to place ethanol for disinfection.
In an embodiment of the present invention, it is provided with a micro electric pump in described base;One is provided with the circuit board Micro electric pump drive circuit, the micro electric pump drive circuit is connected with the MCU;The MCU is also associated with a switch, described Micro electric pump drive circuit is used to drive the micro electric pump;The water inlet end of described micro electric pump is communicated to second pull In box;The output end of the micro electric pump is connected to a needle-based shower nozzle through a catheter;The needle-based shower nozzle alignment second Groove, during in favor of having an injection, user starts micro electric pump by switching, and alcohol is sprayed onto to the afterbody needle insertion site of small white mouse.
In an embodiment of the present invention, the catheter is stretched out by the side wall of the circular pedestal, and is fixed on and is arranged at In clamp bracket on the track.
The advantage of the invention is that:The present invention by the way that small white mouse is limited on a base, using the function of weighing of base, Heartbeat inspecting and infrared temperature detection, while realizing that small white mouse is injected intravenously, obtain more small white mouse life entities The information levied, and cramping body is decontroled after being injected intravenously to small white mouse, small white mouse can be with transparent hemispherical cover body Circular seat body in observed, improve the conventional efficient to small white mouse and the reliability of data.It is noted that this Invention protection is whole device structure, takes pin injection operation for follow-up, is not belonging to protection category of the present invention.
Brief description of the drawings
Fig. 1 is the structural representation of the embodiment of the present invention;
Fig. 2 is the top view of the embodiment of the present invention.
Embodiment
Below in conjunction with the accompanying drawings and embodiment the present invention will be further described.
As depicted in figs. 1 and 2, a kind of small white mouse experimental monitoring device of first embodiment of the invention, including a base 1 and one Transparent hemispherical cover body 2;The base 1 includes the connecting seat 12 of a circular pedestal 11 and the circular side wall of pedestal 11 of connection, described Circular pedestal includes hollow chassis 111 and the weighing pan 112 being arranged in hollow chassis, the weighing pan 111 and hollow bottom Weight sensor 113 is provided between disk;Have in the middle part of the weighing pan in a groove 114, the groove and be provided with an elasticity Being set in pad 115, the elastomeric pad also has an annular pressure sensor 116 for being used to detect the small white mouse rhythm of the heart;The ring An infrared temperature probe 117 for being used to detect small white mouse shell temperature is provided with the middle part of shape pressure sensor;The infrared survey Temperature probe is connected through wire 118 with infrared measurement of temperature module;A rechargeable battery 119 is provided with the hollow chassis, described fills Battery is that a circuit board is powered, and MCU is provided with the circuit board 120, and the MCU is passed with weight sensor, annular pressure Sensor and the connection of infrared measurement of temperature module;The side of the transparent hemispherical cover body 2, which is hinged, to be arranged on circular pedestal 11, described Another side bottom of transparent hemispherical cover body 2 is provided with a hook openings 21;The connection of the circular pedestal 11 and connecting seat 12 Place offers and the second groove 4 is offered on one first groove 3, the connecting seat 12, first groove 3 and the phase of the second groove 4 Connection;The afterbody of second groove 4 is provided with a small white mouse tail cramping body 5;Track 18 is provided with the connecting seat 12, Moved forward and backward on that track for the small white mouse tail cramping body.Because small white mouse is in different size, its tail length It is different, therefore, the position of cramping body is adjusted by the track, can guarantee that the device is applicable different size of small white mouse;Institute A limit assembly 6 is provided with the junction for stating circular pedestal 11 and connecting seat 12;Worn on described transparent hemispherical cover body 2 There are four reset posts 13, the end that the reset post is located in transparent hemispherical cover body sets a spacing net 14, to described multiple When position post is pushed, the spacing guard lives small white mouse, limits the action of small white mouse;The reset post is located at outside transparent hemispherical cover body End be provided with a supporting plate 15;The arc top of the transparent hemispherical cover body is fixedly connected with a screw rod 16, and the screw rod is worn The supporting plate center is crossed, and a limited screw 17 is arranged with the screw rod;So catch small white mouse and small white mouse is placed in circle In pedestal 11, while the tail of small white mouse 8 is placed in the first groove 3 and the second groove 4, transparent hemispherical cover body 2 is covered Down and hook openings 21 are hooked on limit assembly 6, the tail of small white mouse is clamped by small white mouse tail cramping body 5 Firmly, injection operation is being carried out with injection needle 7, if it is desired to keep small white mouse not tampered in transparent hemi cover body, can be by adjusting Limited screw 17 is saved, small white mouse is fixed using the spacing net, it is worth mentioning at this point that, in the present embodiment, described reset post 13 are resetted by spring 27.
In one embodiment of the invention, the reset that described elastomeric pad includes a pad 1151 and is arranged under pad Spring 1152;After back-moving spring compression, the pad can be pressed into described groove 114.Set on the side wall of the base There are a USB charging inlets 121, the charged circuit of output end of the USB charging inlets charges for the rechargeable battery 119.
In the present invention, the connecting seat 12 be rubber connecting seat, rubber connecting seat can deviously with the circular pedestal 11 are connected.The small white mouse tail cramping body 5 includes offering a screwed hole on a square frame 51, the square frame 51 (It is not shown), spiral is provided with a manual screw 52 on the screwed hole, and the square frame 51 is fixed in the second groove 4. Small white mouse afterbody is fixed carrying out tail by rotary screw 52 through square frame 51.
Continuing with referring to Fig. 2, the limit assembly 6 includes two support bars 61 being arranged side by side, and two support bars 61 It is located exactly at the top of the first groove 3;Being set up between the support bar 61 has a spacing steel wire 62.So hook openings 21 can be hooked On spacing steel wire 62, so that transparent hemispherical cover body 2 be fixed.The transparent hemispherical cover body 2 is that Transparent color is saturating Bright hemispherical cover body.So it is easy to the small white mouse situation after observation injection.
In an embodiment of the present invention, the inwall of the hook openings is provided with a resilient rubbber cushion 28, so transparent After hemispherical cover body 2 is covered, the tail of small white mouse can be effectively protected, it is to avoid small white mouse beats, cause tail epidermis to be damaged.
In an embodiment of the present invention, the first pull of two drawing boxs, the wherein left side is provided with the circular pedestal Box 19 is used to place aseptic cotton;Second drawing box 20 on the right is used to place ethanol for disinfection.The two drawing boxs, which are provided with, to be taken out Handle 25;This kind of structure can greatly facilitate the speed that small white mouse vein is had an injection, and being had an injection due to small white mouse vein is needed to tail The skin in portion is carried out disinfection cleaning, therefore, and the structure overcomes to be held when having an injection, it is necessary to be equipped with small of cotton, alcohol etc. in the past Device, not only space-consuming, and carry trouble, for intravenous injection complex procedures.
In an embodiment of the present invention, it is provided with a battery in described base(Do not illustrate in figure), the battery Through a switch(Do not illustrate in figure)Powered for a micro electric pump 26, the water inlet end of described micro electric pump is communicated to described second and taken out In pulling box 20;The output end of the micro electric pump is connected to a needle-based shower nozzle 23 through a catheter 22;The needle-based shower nozzle The second groove 4 is directed at, during in favor of having an injection, user starts micro electric pump by switching, and alcohol is sprayed onto to the afterbody pin of small white mouse Head insert division.
In an embodiment of the present invention, the catheter is stretched out by the side wall of the circular pedestal, and is fixed on and is arranged at In clamp bracket 24 on the track 18.
As shown in fig.2, in one embodiment of the invention, connecting seat 12 can be connected with the circular pedestal 11 deviously Connect.It may be said that the connecting seat is flexible material, such as rubber.It is that user can be by bending the connecting seat, to protect having an injection The Tail skin for demonstrate,proving small white mouse is tight, and user can be allowed preferably to play pin, improves the success rate of acupuncture treatment.
In a word, base of the invention includes the connecting seat of a circular pedestal and connection circular seat body sidewall, described transparent half The side of spherical cover body, which is hinged, to be arranged on circular pedestal, and the junction of circular pedestal and connecting seat offers one first groove, The second groove is offered on the connecting seat, first groove is connected with the second groove;The tail of small white mouse is placed in Tail is clamped by the progress of small white mouse tail cramping body on one groove and the second groove, small white mouse is injected intravenously;Injection Decontroling cramping body small white mouse afterwards can be observed in the circular seat body with transparent hemispherical cover body, simple to operate, and be carried High operating efficiency, if small white mouse is more active, can be carried out spacing to small white mouse by spacing net, overcome existing needs Two people coordinate the drawbacks of being injected to small white mouse, greatly improve the efficiency and success rate of small white mouse intravenous injection.And By small white mouse it is spacing after, the belly of small white mouse is just attached on pad 1151, and pressure sensor can accurately just measure little Bai The heartbeat of mouse, in addition, weighing sensor obtains the weight information of mouse, infrared body temperature is monitored for monitoring after small white mouse injection Shell temperature, improves the conventional efficient to small white mouse and the reliability of data.
The foregoing is only presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with Modification, should all belong to the covering scope of the present invention.

Claims (10)

1. a kind of small white mouse experimental monitoring device, it is characterised in that:Including a base and a transparent hemispherical cover body;The base Connecting seat including a circular pedestal and connection circular seat body sidewall, during the circular pedestal includes hollow chassis and is arranged on Weighing pan on empty chassis, weight sensor is provided between the weighing pan and hollow chassis;Have in the middle part of the weighing pan Being provided with an elastomeric pad, the elastomeric pad to set in one groove, the groove also has one to be used to detect the small white mouse rhythm of the heart Annular pressure sensor;One is provided with the middle part of the annular pressure sensor is used to detect the infrared of small white mouse shell temperature Temperature probe;The infrared temperature probe is connected through wire with infrared measurement of temperature module;A charging is provided with the hollow chassis Battery, described rechargeable battery is powered for a circuit board, is provided with MCU on the circuit board, the MCU and weight sensor, Annular pressure sensor and the connection of infrared measurement of temperature module;The side of the transparent hemispherical cover body, which is hinged, is arranged on circular pedestal On, another lateral edge portion of the transparent hemispherical cover body is provided with a hook openings, so that transparent hemispherical cover body is covered The tail of the small white mouse is stretched out by the hook openings afterwards;It is recessed that the junction of the circular pedestal and connecting seat offers one first The second groove is offered on groove, the connecting seat, first groove is connected with the second groove;The afterbody of second groove It is provided with a small white mouse tail cramping body;Track is provided with the connecting seat, for the small white mouse tail cramping body at this Moved forward and backward on track;A limit assembly is provided with the junction of the circular pedestal and connecting seat;Described transparent hemi Four reset posts are equipped with shape cover body, the end that the reset post is located in transparent hemispherical cover body sets a spacing net, used When being pushed with the reset post, the spacing guard lives small white mouse, limits the action of small white mouse;The reset post is located at transparent hemi End outside shape cover body is provided with a supporting plate;The arc top of the transparent hemispherical cover body is fixedly connected with a screw rod, the spiral shell Bar passes through the supporting plate center, and a limited screw is arranged with the screw rod.
2. a kind of small white mouse experimental monitoring device according to claim 1, it is characterised in that:Described elastomeric pad includes One pad and the back-moving spring being arranged under pad;After back-moving spring compression, the pad can be pressed into described groove It is interior.
3. a kind of small white mouse experimental monitoring device according to claim 1, it is characterised in that:Set on the side wall of the base A USB charging inlets are equipped with, the charged circuit of output end of the USB charging inlets charges for the rechargeable battery.
4. a kind of small white mouse experimental monitoring device according to claim 1, it is characterised in that:The connecting seat connects for rubber Joint chair, rubber connecting seat can be connected with the circular seat body phase deviously.
5. a kind of small white mouse experimental monitoring device according to claim 1, it is characterised in that:The small white mouse tail clamping Body includes a square frame, and offering spiral on a screwed hole, the screwed hole on the square frame is provided with a manual spiral shell Silk, the square frame is fixed in the second groove.
6. a kind of small white mouse experimental monitoring device according to claim 1, it is characterised in that:The limit assembly includes two The individual support bar being arranged side by side, and two support bars are located exactly at the top of the first groove;Being set up between the support bar has one Spacing steel wire.
7. a kind of small white mouse experimental monitoring device according to claim 1, it is characterised in that:The inwall of the hook openings It is provided with a resilient rubbber cushion.
8. a kind of small white mouse experimental monitoring device according to claim 1, it is characterised in that:Set on the circular pedestal There are two drawing boxs, wherein first drawing box on the left side is used to place aseptic cotton;Second drawing box on the right, which is used to place, to be sterilized Alcohol.
9. a kind of small white mouse experimental monitoring device according to claim 8, it is characterised in that:It is provided with described base One micro electric pump;A micro electric pump drive circuit, the micro electric pump drive circuit and the MCU are provided with the circuit board Connection;The MCU is also associated with a switch, and the micro electric pump drive circuit is used to drive the micro electric pump;Described is micro- The water inlet end of type electric pump is communicated in second drawing box;The output end of the micro electric pump is connected to a pin through a catheter Hair style shower nozzle;The needle-based shower nozzle is directed at the second groove, during in favor of having an injection, and user starts micro electric pump by switching, will Alcohol is sprayed onto the afterbody needle insertion site of small white mouse.
10. a kind of small white mouse experimental monitoring device according to claim 9, it is characterised in that:The catheter is by described The side wall of circular pedestal stretches out, and is fixed in the clamp bracket being arranged on the track.
CN201610672160.XA 2016-08-16 2016-08-16 A kind of small white mouse experimental monitoring device Active CN106093370B (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104013478A (en) * 2014-06-25 2014-09-03 李晓峰 Experimental rat fixing barrel
CN204318966U (en) * 2014-12-05 2015-05-13 黑占财 The special testing fixture of a kind of animal and veterinary
CN204364167U (en) * 2014-12-23 2015-06-03 辽宁中医药大学 A kind of rat fixing device
CN204446167U (en) * 2015-01-14 2015-07-08 苏州大学 Mouse tail vein injection experimental provision
CN204995608U (en) * 2015-10-02 2016-01-27 姜守丹 Inspecting device special for animal husbandry and veterinary
CN105287040A (en) * 2015-12-01 2016-02-03 上海市第一人民医院 Medical experiment animal treating and fixing equipment
CN205181526U (en) * 2015-12-01 2016-04-27 上海市第一人民医院 Fixing device is handled to medical experiment mouse
CN105662636A (en) * 2016-03-10 2016-06-15 苏州大学 Device for animal tail vein injection

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104013478A (en) * 2014-06-25 2014-09-03 李晓峰 Experimental rat fixing barrel
CN204318966U (en) * 2014-12-05 2015-05-13 黑占财 The special testing fixture of a kind of animal and veterinary
CN204364167U (en) * 2014-12-23 2015-06-03 辽宁中医药大学 A kind of rat fixing device
CN204446167U (en) * 2015-01-14 2015-07-08 苏州大学 Mouse tail vein injection experimental provision
CN204995608U (en) * 2015-10-02 2016-01-27 姜守丹 Inspecting device special for animal husbandry and veterinary
CN105287040A (en) * 2015-12-01 2016-02-03 上海市第一人民医院 Medical experiment animal treating and fixing equipment
CN205181526U (en) * 2015-12-01 2016-04-27 上海市第一人民医院 Fixing device is handled to medical experiment mouse
CN105662636A (en) * 2016-03-10 2016-06-15 苏州大学 Device for animal tail vein injection

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